id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269259-rpvl4vmu	Waltl, Inken	Microglia have a protective role in viral encephalitis-induced seizure development and hippocampal damage	2018-09-11		.txt	text/plain	11309	635	51	Significant brain invasion of CD8 + cytotoxic T lymphocytes (CD8 + T effector cells), which are thought to play a significant role in viral clearance in the TMEV model in mice (Libbey and Fujinami, 2011; DePaula-Silva et al., 2017) , was observed both in infected controls and infected mice treated with PLX5622, without significant inter-group difference (Fig. 4B ). The brain invasion of Foxp3 + regulatory T cells (Tregs) was increased in both infected controls and PLX5622-treated infected mice to a similar extent without significant inter-group difference (Fig. 4D) . The present data show that these consequences of microglia depletion are virus specific, because we did not observe a decrease but a significant increase in infiltration of Foxp3 + Tregs in hippocampus and spinal cord and only a relatively small reduction in brain invasion of CD4 + T cells in TMEV-infected, PLX5622-treated mice compared to infected controls, although the invasion of CD4 + CD44 + T cells was markedly reduced by microglia depletion.	./cache/cord-269259-rpvl4vmu.txt	./txt/cord-269259-rpvl4vmu.txt