id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-272143-6ej3eibd	Benavides‐Nieto, Marta	The role of respiratory viruses in children with humoral immunodeficiency on immunoglobulin replacement therapy	2018-12-21		.txt	text/plain	1875	133	40	We have evaluated these infections in children with humoral immunodeficiencies who required immunoglobulin replacement therapy, considering their relationship with symptoms, lung function, bacterial co‐infection, and outcomes. CONCLUSIONS: In our experience, viral respiratory tract infections can cause significant respiratory symptoms and impaired lung function, in children with HID, despite immunoglobulin replacement therapy. Children with severe T-cell immunodeficiencies present impaired clearance of respiratory viruses, and pulmonary complications of viral infections are leading causes of morbidity and mortality in this group of patients. 1 However, the role of respiratory viruses in children with other types of primary immunodeficiency (PID), mainly those with humoral immunodeficiencies (HID) or diseases of immune dysregulation, has hardly been studied. 2, 7 We report, to the best of our knowledge, the first study that analyses respiratory viruses in pediatric patients with predominantly antibody deficiency who required IRT, considering their relationship with clinical symptoms and pulmonary function, bacterial co-infection, treatment and outcomes.	./cache/cord-272143-6ej3eibd.txt	./txt/cord-272143-6ej3eibd.txt