id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281259-1wptx49j	Kim, Danbi	Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report	2019-02-15		.txt	text/plain	2308	139	48	title: Pneumocystis jirovecii pneumonia as an initial manifestation of hyper-IgM syndrome in an infant: A case report Human immunodeficiency virus infection, malignancy, solid organ or hematopoietic cell transplantation, and primary immune deficiency compose the risk factors for Pneumocystis pneumonia (PCP) in children, and PCP can be an initial clinical manifestation of primary immune deficiency. [9] [10] [11] [12] Especially, 43% of infants diagnosed with X-linked HIGM syndrome before 1 year of age initially presented with PCP. However, pediatricians should consider that PCP can be an initial clinical presentation of PID, [4] [5] [6] and therefore, PCP should be suspected in infants with severe interstitial pneumonia accompanying normal breathing sounds when common viral and bacterial pathogens are not identified, even though the infants may show no evidence of immune deficiency. In conclusion, we report an infant who presented with severe interstitial pneumonia and was diagnosed with PCP as the initial manifestation of underlying HIGM syndrome. Pneumocystis jiroveci pneumonia revealing de novo mutation causing X-linked hyper-IgM syndrome in an infant male.	./cache/cord-281259-1wptx49j.txt	./txt/cord-281259-1wptx49j.txt