id author title date pages extension mime words sentences flesch summary cache txt cord-286607-5i406twr Esposito, Susanna The Gut Microbiota-Host Partnership as a Potential Driver of Kawasaki Syndrome 2019-04-05 .txt text/plain 6223 250 30 Kawasaki syndrome (KS) is a necrotizing vasculitis of smalland medium-sized vessels mostly affecting children under 5 years of age; a host of clinical and epidemiological data supports the notion that KS might result from an infectious disease. All studies available to date have confirmed that an imbalance in the gut microbiota might indirectly interfere with the normal function of innate and adaptive immunity, and that variable microbiota interactions with environmental factors, mainly infectious agents, might selectively drive the development of KS in genetically susceptible children. The microbiota, a microbial community of trillions of microorganisms and at least 1,000 different bacterial species, some eukaryotic fungi and viruses, and which covers every surface of the human body, plays a contributory role in many infections, immune-mediated disorders, rheumatologic diseases, and disorders of the nervous system. ./cache/cord-286607-5i406twr.txt ./txt/cord-286607-5i406twr.txt