id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-286843-8qh1pblc	Quah, Jessica	Impact of microbial Aetiology on mortality in severe community-acquired pneumonia	2018-09-04		.txt	text/plain	4060	215	38	Univariate and multivariate logistic regression showed that serum procalcitonin, APACHE II severity score and mixed viral-bacterial infection were associated with increased risk of hospital mortality. Postulated prohibitive factors against the routine performance of viral diagnostics tests in patients with severe CAP may include a lack of clear clinical guidelines, perceived low cost-effectiveness and the paucity of effective anti-viral therapies for respiratory viruses other than influenza. Our primary hypothesis was that respiratory viruses were important causative pathogens in severe CAP and was associated with increased mortality when present with bacterial pathogens in mixed viral-bacterial co-infections. performed a prospective observational study on physician practices in the use of respiratory virus diagnostics demonstrating that despite clinical guideline recommendations on testing of respiratory viruses during influenza season, less than half of patients admitted to the intensive care unit with pneumonia were tested for viral pathogens [14] .	./cache/cord-286843-8qh1pblc.txt	./txt/cord-286843-8qh1pblc.txt