id author title date pages extension mime words sentences flesch summary cache txt cord-289096-wuegn0jg Wang, Liang Bat-Origin Coronaviruses Expand Their Host Range to Pigs 2018-04-18 .txt text/plain 1209 69 57 Gao 1,3,4, * Infections with bat-origin coronaviruses have caused severe illness in humans by 'host jump'. The host range expansion of coronaviruses (CoVs) from wildlife to humans via genetic recombination and/or mutations on the receptor-binding domain in the spike (S) gene is well established and results in several diseases with high fatality rates, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) [ [4] . Thus, pigs are regarded as mixing vessels for IAVs. However, pigs were not known to be susceptible to bat-origin coronaviruses until recently, when two independent groups reported the detection of novel swine enteric alphacoronaviruses (SeACoVs) distinct from known swine coronaviruses (with one group successfully isolating live virus). The isolation of SeACoV from ill piglets expands our knowledge of the host range of bat-origin coronaviruses, and potentially poses a threat to public health. ./cache/cord-289096-wuegn0jg.txt ./txt/cord-289096-wuegn0jg.txt