id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-290861-5bxvenue	Ashwell, M.	Characterization of gene expression in naturally occurring feline degenerative joint disease-associated pain	2018-11-19		.txt	text/plain	4901	225	51	Expression of an investigator-selected set of pain signaling genes (including ASIC3, ATF3, COX2, CX3CL1, NAV1.7, NAV1.8, NAV1.9, NGF, NK1R, TNFα, TRKA) in lumbar spinal cord dorsal horn and lumbar dorsal root ganglia tissues from clinically healthy cats and cats with DJD were studied using quantitative RT-PCR (qPCR). After the most stable reference genes were identified, a selection of genes previously associated with nociception in rodent models, and of interest to the authors, were examined using qPCR in the same samples to allow us to start characterizing the neurobiological signature of pain associated with DJD in cats. After a set of stable reference genes were identified for each tissue type, 13 genes associated with pain in rodents were selected (based on current knowledge of genes involved in pain states (Foulkes and Wood, 2008) and their expression levels compared in the DRG from DJD-affected and healthy samples.	./cache/cord-290861-5bxvenue.txt	./txt/cord-290861-5bxvenue.txt