id author title date pages extension mime words sentences flesch summary cache txt cord-291704-z6e7pmk8 Chen, Bin Development and characterization of a new cell line derived from European eel Anguilla anguilla kidney 2018-11-14 .txt text/plain 4358 226 58 title: Development and characterization of a new cell line derived from European eel Anguilla anguilla kidney A new cell line derived from the kidney of European eel, Anguilla anguilla, has been established and characterized. As an amino acid-rich nutrient medium forming a CO 2 -free system, L-15 has been used for successful application on fish cell lines and made CO 2 incubators unnecessary, which in turn significantly improved the stability and convenience of cell culture (Leibovitz, 1963 (Leibovitz, , 1977 . In this study, the expression of CYP450 showed a significantly long-term upregulation after poly (I: C) induction, indicating the potential of EK cell line for toxicological and pharmacological analysis of aquatic pollutants. To define the responses of this cell line to immune stimulations, the changes of the expression of interferon regulatory factor-7 (irf7, GenBank accession no. ./cache/cord-291704-z6e7pmk8.txt ./txt/cord-291704-z6e7pmk8.txt