id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-297265-pwq5gir9	Chiu, Charles	Cutting-Edge Infectious Disease Diagnostics with CRISPR	2018-06-13		.txt	text/plain	1911	95	47	Three recent Science articles (Chen et al., 2018; Gootenberg et al., 2018; Myhrvold et al., 2018) describe the use of CRISPR-Cas technology to develop point-of-care diagnostics that directly detect viruses from clinical samples. Three recent Science articles (Chen et al., 2018; Gootenberg et al., 2018; Myhrvold et al., 2018) describe the use of CRISPR-Cas technology to develop point-of-care diagnostics that directly detect viruses from clinical samples. In three papers published in Science (Chen et al., 2018; Gootenberg et al., 2018; Myhrvold et al., 2018) , two groups report the use of CRISPR-Cas-based technology for the development of molecular diagnostic assays, with a focus on infectious diseases. After collection of clinical samples in a point-of-care setting, such as the patient bedside, medical office, hospital ward, or in the field, the CAS12a-or CAS13-based assay can be performed directly from the sample in under 2 hr, without the need for a separate DNA or RNA extraction step.	./cache/cord-297265-pwq5gir9.txt	./txt/cord-297265-pwq5gir9.txt