id author title date pages extension mime words sentences flesch summary cache txt cord-314567-purplsjn Fernández-Ponce, Cecilia Ultrastructural Localization and Molecular Associations of HCV Capsid Protein in Jurkat T Cells 2018-01-04 .txt text/plain 7978 382 41 HCV-core associated proteins are implicated in RNA processing and RNA virus infection as well as in functions previously shown to be altered in Hepatitis C virus core expressing CD4 + T cells, such as cell cycle delay, decreased proliferation, and induction of a regulatory phenotype. HCV-core associated proteins are implicated in RNA processing and RNA virus infection as well as in functions previously shown to be altered in Hepatitis C virus core expressing CD4 + T cells, such as cell cycle delay, decreased proliferation, and induction of a regulatory phenotype. As studies using the whole virus do not allow for the elucidation of the specific molecular mechanisms in which each protein is implicated, in this work, we focused on a single viral protein, showing that in CD4 + T cells, HCV core protein mostly localizes in the nucleus and specifically in the nucleolus where it is greatly enriched. ./cache/cord-314567-purplsjn.txt ./txt/cord-314567-purplsjn.txt