id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322395-xeq4yix4	Nurtay, Anel	Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis	2019-01-09		.txt	text/plain	9404	488	54	We investigate the dynamics of a wild-type viral strain which generates mutant strains differing in phenotypic properties for infectivity, virulence and mutation rates. We study, by means of a mathematical model and bifurcation analysis, conditions under which the wild-type and mutant viruses, which compete for the same host cells, can coexist. Consequently, the bifurcation diagram in figure 3b shows that for mutant-type infection rates given by a m , 0.86, the coexistence state v 3 is stable whereas the virus-free state v 1 is unstable. As predicted from linear stability analysis, the Hopf bifurcation curve associated with the wt-free state v 2 does not depend on the infection rate of the wt virus a w and thus appears as a straight line given by a m ¼ 1.55.	./cache/cord-322395-xeq4yix4.txt	./txt/cord-322395-xeq4yix4.txt