id sid tid token lemma pos cord-012719-5qa0e4xt 1 1 key key JJ cord-012719-5qa0e4xt 1 2 : : : cord-012719-5qa0e4xt 1 3 cord-012719 cord-012719 NNP cord-012719-5qa0e4xt 1 4 - - HYPH cord-012719-5qa0e4xt 1 5 5qa0e4xt 5qa0e4xt CD cord-012719-5qa0e4xt 1 6 authors author NNS cord-012719-5qa0e4xt 1 7 : : : cord-012719-5qa0e4xt 1 8 Lim Lim NNP cord-012719-5qa0e4xt 1 9 , , , cord-012719-5qa0e4xt 1 10 Su Su NNP cord-012719-5qa0e4xt 1 11 - - HYPH cord-012719-5qa0e4xt 1 12 Ho Ho NNP cord-012719-5qa0e4xt 1 13 ; ; : cord-012719-5qa0e4xt 1 14 Gu Gu NNP cord-012719-5qa0e4xt 1 15 , , , cord-012719-5qa0e4xt 1 16 Won Won NNP cord-012719-5qa0e4xt 1 17 Mo Mo NNP cord-012719-5qa0e4xt 1 18 ; ; : cord-012719-5qa0e4xt 1 19 Cha Cha NNP cord-012719-5qa0e4xt 1 20 , , , cord-012719-5qa0e4xt 1 21 Soon soon RB cord-012719-5qa0e4xt 1 22 Cheol Cheol NNP cord-012719-5qa0e4xt 1 23 title title NN cord-012719-5qa0e4xt 1 24 : : : cord-012719-5qa0e4xt 1 25 Comparison comparison NN cord-012719-5qa0e4xt 1 26 of of IN cord-012719-5qa0e4xt 1 27 the the DT cord-012719-5qa0e4xt 1 28 retinal retinal JJ cord-012719-5qa0e4xt 1 29 nerve nerve NN cord-012719-5qa0e4xt 1 30 fiber fiber NN cord-012719-5qa0e4xt 1 31 layer layer NN cord-012719-5qa0e4xt 1 32 and and CC cord-012719-5qa0e4xt 1 33 ganglion ganglion NN cord-012719-5qa0e4xt 1 34 cell cell NN cord-012719-5qa0e4xt 1 35 complex complex JJ cord-012719-5qa0e4xt 1 36 thickness thickness NN cord-012719-5qa0e4xt 1 37 in in IN cord-012719-5qa0e4xt 1 38 Korean korean JJ cord-012719-5qa0e4xt 1 39 patients patient NNS cord-012719-5qa0e4xt 1 40 with with IN cord-012719-5qa0e4xt 1 41 unilateral unilateral JJ cord-012719-5qa0e4xt 1 42 exfoliation exfoliation NN cord-012719-5qa0e4xt 1 43 syndrome syndrome NN cord-012719-5qa0e4xt 1 44 and and CC cord-012719-5qa0e4xt 1 45 healthy healthy JJ cord-012719-5qa0e4xt 1 46 subjects subject NNS cord-012719-5qa0e4xt 1 47 date date NN cord-012719-5qa0e4xt 1 48 : : : cord-012719-5qa0e4xt 1 49 2019 2019 CD cord-012719-5qa0e4xt 1 50 - - HYPH cord-012719-5qa0e4xt 1 51 11 11 CD cord-012719-5qa0e4xt 1 52 - - SYM cord-012719-5qa0e4xt 1 53 12 12 CD cord-012719-5qa0e4xt 1 54 journal journal NN cord-012719-5qa0e4xt 1 55 : : : cord-012719-5qa0e4xt 1 56 Eye Eye NNP cord-012719-5qa0e4xt 1 57 ( ( -LRB- cord-012719-5qa0e4xt 1 58 Lond Lond NNP cord-012719-5qa0e4xt 1 59 ) ) -RRB- cord-012719-5qa0e4xt 1 60 DOI DOI NNP cord-012719-5qa0e4xt 1 61 : : : cord-012719-5qa0e4xt 2 1 10.1038 10.1038 CD cord-012719-5qa0e4xt 2 2 / / SYM cord-012719-5qa0e4xt 2 3 s41433 s41433 JJ cord-012719-5qa0e4xt 2 4 - - HYPH cord-012719-5qa0e4xt 2 5 019 019 CD cord-012719-5qa0e4xt 2 6 - - HYPH cord-012719-5qa0e4xt 2 7 0642 0642 CD cord-012719-5qa0e4xt 2 8 - - SYM cord-012719-5qa0e4xt 2 9 5 5 CD cord-012719-5qa0e4xt 2 10 sha sha NNP cord-012719-5qa0e4xt 2 11 : : : cord-012719-5qa0e4xt 3 1 a0016f3ba4f84b0820b745360d5b1e9622ed2406 a0016f3ba4f84b0820b745360d5b1e9622ed2406 NNP cord-012719-5qa0e4xt 3 2 doc_id doc_id CD cord-012719-5qa0e4xt 3 3 : : : cord-012719-5qa0e4xt 3 4 12719 12719 CD cord-012719-5qa0e4xt 3 5 cord_uid cord_uid NNS cord-012719-5qa0e4xt 3 6 : : : cord-012719-5qa0e4xt 3 7 5qa0e4xt 5qa0e4xt CD cord-012719-5qa0e4xt 3 8 PURPOSE purpose NN cord-012719-5qa0e4xt 3 9 : : : cord-012719-5qa0e4xt 4 1 To to TO cord-012719-5qa0e4xt 4 2 compare compare VB cord-012719-5qa0e4xt 4 3 retinal retinal JJ cord-012719-5qa0e4xt 4 4 nerve nerve NN cord-012719-5qa0e4xt 4 5 fiber fiber NN cord-012719-5qa0e4xt 4 6 layer layer NN cord-012719-5qa0e4xt 4 7 ( ( -LRB- cord-012719-5qa0e4xt 4 8 RNFL RNFL NNP cord-012719-5qa0e4xt 4 9 ) ) -RRB- cord-012719-5qa0e4xt 4 10 and and CC cord-012719-5qa0e4xt 4 11 ganglion ganglion NN cord-012719-5qa0e4xt 4 12 cell cell NN cord-012719-5qa0e4xt 4 13 complex complex NN cord-012719-5qa0e4xt 4 14 ( ( -LRB- cord-012719-5qa0e4xt 4 15 GCC gcc NN cord-012719-5qa0e4xt 4 16 ) ) -RRB- cord-012719-5qa0e4xt 4 17 thickness thickness NN cord-012719-5qa0e4xt 4 18 in in IN cord-012719-5qa0e4xt 4 19 patients patient NNS cord-012719-5qa0e4xt 4 20 with with IN cord-012719-5qa0e4xt 4 21 unilateral unilateral JJ cord-012719-5qa0e4xt 4 22 exfoliation exfoliation NN cord-012719-5qa0e4xt 4 23 syndrome syndrome NN cord-012719-5qa0e4xt 4 24 ( ( -LRB- cord-012719-5qa0e4xt 4 25 XFS XFS NNP cord-012719-5qa0e4xt 4 26 ) ) -RRB- cord-012719-5qa0e4xt 4 27 and and CC cord-012719-5qa0e4xt 4 28 age age NN cord-012719-5qa0e4xt 4 29 - - HYPH cord-012719-5qa0e4xt 4 30 matched match VBN cord-012719-5qa0e4xt 4 31 controls control NNS cord-012719-5qa0e4xt 4 32 using use VBG cord-012719-5qa0e4xt 4 33 spectral spectral JJ cord-012719-5qa0e4xt 4 34 domain domain NN cord-012719-5qa0e4xt 4 35 - - HYPH cord-012719-5qa0e4xt 4 36 optical optical JJ cord-012719-5qa0e4xt 4 37 coherence coherence NN cord-012719-5qa0e4xt 4 38 tomography tomography NN cord-012719-5qa0e4xt 4 39 ( ( -LRB- cord-012719-5qa0e4xt 4 40 SD SD NNP cord-012719-5qa0e4xt 4 41 - - HYPH cord-012719-5qa0e4xt 4 42 OCT OCT NNP cord-012719-5qa0e4xt 4 43 ) ) -RRB- cord-012719-5qa0e4xt 4 44 . . . cord-012719-5qa0e4xt 5 1 MATERIALS materials NN cord-012719-5qa0e4xt 5 2 AND and CC cord-012719-5qa0e4xt 5 3 METHODS method NNS cord-012719-5qa0e4xt 5 4 : : : cord-012719-5qa0e4xt 6 1 This this DT cord-012719-5qa0e4xt 6 2 prospective prospective JJ cord-012719-5qa0e4xt 6 3 case case NN cord-012719-5qa0e4xt 6 4 – – : cord-012719-5qa0e4xt 6 5 control control NN cord-012719-5qa0e4xt 6 6 study study NN cord-012719-5qa0e4xt 6 7 included include VBD cord-012719-5qa0e4xt 6 8 54 54 CD cord-012719-5qa0e4xt 6 9 eyes eye NNS cord-012719-5qa0e4xt 6 10 ( ( -LRB- cord-012719-5qa0e4xt 6 11 the the DT cord-012719-5qa0e4xt 6 12 XFS xfs NN cord-012719-5qa0e4xt 6 13 - - HYPH cord-012719-5qa0e4xt 6 14 affected affect VBN cord-012719-5qa0e4xt 6 15 and and CC cord-012719-5qa0e4xt 6 16 the the DT cord-012719-5qa0e4xt 6 17 fellow fellow JJ cord-012719-5qa0e4xt 6 18 eyes eye NNS cord-012719-5qa0e4xt 6 19 ) ) -RRB- cord-012719-5qa0e4xt 6 20 of of IN cord-012719-5qa0e4xt 6 21 27 27 CD cord-012719-5qa0e4xt 6 22 unilateral unilateral JJ cord-012719-5qa0e4xt 6 23 XFS xfs NN cord-012719-5qa0e4xt 6 24 patients patient NNS cord-012719-5qa0e4xt 6 25 and and CC cord-012719-5qa0e4xt 6 26 27 27 CD cord-012719-5qa0e4xt 6 27 eyes eye NNS cord-012719-5qa0e4xt 6 28 of of IN cord-012719-5qa0e4xt 6 29 27 27 CD cord-012719-5qa0e4xt 6 30 age age NN cord-012719-5qa0e4xt 6 31 - - HYPH cord-012719-5qa0e4xt 6 32 matched match VBN cord-012719-5qa0e4xt 6 33 control control NN cord-012719-5qa0e4xt 6 34 subjects subject NNS cord-012719-5qa0e4xt 6 35 . . . cord-012719-5qa0e4xt 7 1 The the DT cord-012719-5qa0e4xt 7 2 RNFL RNFL NNP cord-012719-5qa0e4xt 7 3 and and CC cord-012719-5qa0e4xt 7 4 GCC GCC NNP cord-012719-5qa0e4xt 7 5 thicknesses thickness NNS cord-012719-5qa0e4xt 7 6 were be VBD cord-012719-5qa0e4xt 7 7 measured measure VBN cord-012719-5qa0e4xt 7 8 using use VBG cord-012719-5qa0e4xt 7 9 SD SD NNP cord-012719-5qa0e4xt 7 10 - - HYPH cord-012719-5qa0e4xt 7 11 OCT OCT NNP cord-012719-5qa0e4xt 7 12 ( ( -LRB- cord-012719-5qa0e4xt 7 13 RT RT NNP cord-012719-5qa0e4xt 7 14 - - HYPH cord-012719-5qa0e4xt 7 15 Vue Vue NNP cord-012719-5qa0e4xt 7 16 100 100 CD cord-012719-5qa0e4xt 7 17 , , , cord-012719-5qa0e4xt 7 18 Optovue Optovue NNP cord-012719-5qa0e4xt 7 19 , , , cord-012719-5qa0e4xt 7 20 Fremont Fremont NNP cord-012719-5qa0e4xt 7 21 , , , cord-012719-5qa0e4xt 7 22 CA CA NNP cord-012719-5qa0e4xt 7 23 ) ) -RRB- cord-012719-5qa0e4xt 7 24 after after IN cord-012719-5qa0e4xt 7 25 pupillary pupillary JJ cord-012719-5qa0e4xt 7 26 dilation dilation NN cord-012719-5qa0e4xt 7 27 . . . cord-012719-5qa0e4xt 8 1 RNFL RNFL NNP cord-012719-5qa0e4xt 8 2 and and CC cord-012719-5qa0e4xt 8 3 GCC GCC NNP cord-012719-5qa0e4xt 8 4 thicknesses thickness NNS cord-012719-5qa0e4xt 8 5 were be VBD cord-012719-5qa0e4xt 8 6 compared compare VBN cord-012719-5qa0e4xt 8 7 between between IN cord-012719-5qa0e4xt 8 8 case case NN cord-012719-5qa0e4xt 8 9 and and CC cord-012719-5qa0e4xt 8 10 control control NN cord-012719-5qa0e4xt 8 11 groups group NNS cord-012719-5qa0e4xt 8 12 . . . cord-012719-5qa0e4xt 9 1 RESULTS result NNS cord-012719-5qa0e4xt 9 2 : : : cord-012719-5qa0e4xt 10 1 The the DT cord-012719-5qa0e4xt 10 2 mean mean JJ cord-012719-5qa0e4xt 10 3 age age NN cord-012719-5qa0e4xt 10 4 of of IN cord-012719-5qa0e4xt 10 5 XFS xfs JJ cord-012719-5qa0e4xt 10 6 patients patient NNS cord-012719-5qa0e4xt 10 7 was be VBD cord-012719-5qa0e4xt 10 8 73.3 73.3 CD cord-012719-5qa0e4xt 10 9 years year NNS cord-012719-5qa0e4xt 10 10 and and CC cord-012719-5qa0e4xt 10 11 that that DT cord-012719-5qa0e4xt 10 12 of of IN cord-012719-5qa0e4xt 10 13 age age NN cord-012719-5qa0e4xt 10 14 - - HYPH cord-012719-5qa0e4xt 10 15 matched match VBN cord-012719-5qa0e4xt 10 16 controls control NNS cord-012719-5qa0e4xt 10 17 was be VBD cord-012719-5qa0e4xt 10 18 74.3 74.3 CD cord-012719-5qa0e4xt 10 19 years year NNS cord-012719-5qa0e4xt 10 20 . . . cord-012719-5qa0e4xt 11 1 Both both DT cord-012719-5qa0e4xt 11 2 groups group NNS cord-012719-5qa0e4xt 11 3 demonstrated demonstrate VBD cord-012719-5qa0e4xt 11 4 a a DT cord-012719-5qa0e4xt 11 5 male male JJ cord-012719-5qa0e4xt 11 6 preponderance preponderance NN cord-012719-5qa0e4xt 11 7 . . . cord-012719-5qa0e4xt 12 1 Superior Superior NNP cord-012719-5qa0e4xt 12 2 RNFL RNFL NNP cord-012719-5qa0e4xt 12 3 thickness thickness NN cord-012719-5qa0e4xt 12 4 of of IN cord-012719-5qa0e4xt 12 5 XFS xfs NN cord-012719-5qa0e4xt 12 6 - - HYPH cord-012719-5qa0e4xt 12 7 affected affect VBN cord-012719-5qa0e4xt 12 8 eyes eye NNS cord-012719-5qa0e4xt 12 9 were be VBD cord-012719-5qa0e4xt 12 10 significantly significantly RB cord-012719-5qa0e4xt 12 11 thinner thin JJR cord-012719-5qa0e4xt 12 12 than than IN cord-012719-5qa0e4xt 12 13 those those DT cord-012719-5qa0e4xt 12 14 of of IN cord-012719-5qa0e4xt 12 15 the the DT cord-012719-5qa0e4xt 12 16 healthy healthy JJ cord-012719-5qa0e4xt 12 17 age age NN cord-012719-5qa0e4xt 12 18 - - HYPH cord-012719-5qa0e4xt 12 19 matched match VBN cord-012719-5qa0e4xt 12 20 controls control NNS cord-012719-5qa0e4xt 12 21 ( ( -LRB- cord-012719-5qa0e4xt 12 22 P p NN cord-012719-5qa0e4xt 12 23 = = SYM cord-012719-5qa0e4xt 12 24 0.002 0.002 CD cord-012719-5qa0e4xt 12 25 by by IN cord-012719-5qa0e4xt 12 26 ANOVA ANOVA NNP cord-012719-5qa0e4xt 12 27 ) ) -RRB- cord-012719-5qa0e4xt 12 28 . . . cord-012719-5qa0e4xt 13 1 There there EX cord-012719-5qa0e4xt 13 2 were be VBD cord-012719-5qa0e4xt 13 3 no no DT cord-012719-5qa0e4xt 13 4 statistically statistically RB cord-012719-5qa0e4xt 13 5 significant significant JJ cord-012719-5qa0e4xt 13 6 differences difference NNS cord-012719-5qa0e4xt 13 7 in in IN cord-012719-5qa0e4xt 13 8 the the DT cord-012719-5qa0e4xt 13 9 RNFL RNFL NNP cord-012719-5qa0e4xt 13 10 thickness thickness NN cord-012719-5qa0e4xt 13 11 between between IN cord-012719-5qa0e4xt 13 12 both both DT cord-012719-5qa0e4xt 13 13 eyes eye NNS cord-012719-5qa0e4xt 13 14 of of IN cord-012719-5qa0e4xt 13 15 unilateral unilateral JJ cord-012719-5qa0e4xt 13 16 XFS xfs NN cord-012719-5qa0e4xt 13 17 patients patient NNS cord-012719-5qa0e4xt 13 18 . . . cord-012719-5qa0e4xt 14 1 Moreover moreover RB cord-012719-5qa0e4xt 14 2 , , , cord-012719-5qa0e4xt 14 3 superior superior JJ cord-012719-5qa0e4xt 14 4 GCC gcc NN cord-012719-5qa0e4xt 14 5 thickness thickness NN cord-012719-5qa0e4xt 14 6 of of IN cord-012719-5qa0e4xt 14 7 both both DT cord-012719-5qa0e4xt 14 8 eyes eye NNS cord-012719-5qa0e4xt 14 9 in in IN cord-012719-5qa0e4xt 14 10 unilateral unilateral JJ cord-012719-5qa0e4xt 14 11 XFS xfs NN cord-012719-5qa0e4xt 14 12 patients patient NNS cord-012719-5qa0e4xt 14 13 were be VBD cord-012719-5qa0e4xt 14 14 thinner thin JJR cord-012719-5qa0e4xt 14 15 than than IN cord-012719-5qa0e4xt 14 16 those those DT cord-012719-5qa0e4xt 14 17 in in IN cord-012719-5qa0e4xt 14 18 controls control NNS cord-012719-5qa0e4xt 14 19 ( ( -LRB- cord-012719-5qa0e4xt 14 20 P p NN cord-012719-5qa0e4xt 14 21 = = SYM cord-012719-5qa0e4xt 14 22 0.002 0.002 CD cord-012719-5qa0e4xt 14 23 by by IN cord-012719-5qa0e4xt 14 24 ANOVA ANOVA NNP cord-012719-5qa0e4xt 14 25 ) ) -RRB- cord-012719-5qa0e4xt 14 26 . . . cord-012719-5qa0e4xt 15 1 CONCLUSIONS conclusion NNS cord-012719-5qa0e4xt 15 2 : : : cord-012719-5qa0e4xt 16 1 Thinner thin JJR cord-012719-5qa0e4xt 16 2 RNFL RNFL NNP cord-012719-5qa0e4xt 16 3 and and CC cord-012719-5qa0e4xt 16 4 GCC GCC NNP cord-012719-5qa0e4xt 16 5 thicknesses thickness NNS cord-012719-5qa0e4xt 16 6 were be VBD cord-012719-5qa0e4xt 16 7 observed observe VBN cord-012719-5qa0e4xt 16 8 in in IN cord-012719-5qa0e4xt 16 9 unilateral unilateral JJ cord-012719-5qa0e4xt 16 10 XFS xfs NN cord-012719-5qa0e4xt 16 11 patients patient NNS cord-012719-5qa0e4xt 16 12 without without IN cord-012719-5qa0e4xt 16 13 visual visual JJ cord-012719-5qa0e4xt 16 14 field field NN cord-012719-5qa0e4xt 16 15 defects defect NNS cord-012719-5qa0e4xt 16 16 . . . cord-012719-5qa0e4xt 17 1 These these DT cord-012719-5qa0e4xt 17 2 findings finding NNS cord-012719-5qa0e4xt 17 3 imply imply VBP cord-012719-5qa0e4xt 17 4 that that IN cord-012719-5qa0e4xt 17 5 XFS XFS NNP cord-012719-5qa0e4xt 17 6 itself -PRON- PRP cord-012719-5qa0e4xt 17 7 might may MD cord-012719-5qa0e4xt 17 8 be be VB cord-012719-5qa0e4xt 17 9 a a DT cord-012719-5qa0e4xt 17 10 risk risk NN cord-012719-5qa0e4xt 17 11 factor factor NN cord-012719-5qa0e4xt 17 12 for for IN cord-012719-5qa0e4xt 17 13 development development NN cord-012719-5qa0e4xt 17 14 of of IN cord-012719-5qa0e4xt 17 15 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 17 16 optic optic JJ cord-012719-5qa0e4xt 17 17 disc disc NN cord-012719-5qa0e4xt 17 18 and and CC cord-012719-5qa0e4xt 17 19 RNFL RNFL NNP cord-012719-5qa0e4xt 17 20 damage damage NN cord-012719-5qa0e4xt 17 21 . . . cord-012719-5qa0e4xt 18 1 Exfoliative exfoliative JJ cord-012719-5qa0e4xt 18 2 glaucoma glaucoma NN cord-012719-5qa0e4xt 18 3 ( ( -LRB- cord-012719-5qa0e4xt 18 4 XFG XFG NNP cord-012719-5qa0e4xt 18 5 ) ) -RRB- cord-012719-5qa0e4xt 18 6 is be VBZ cord-012719-5qa0e4xt 18 7 a a DT cord-012719-5qa0e4xt 18 8 common common JJ cord-012719-5qa0e4xt 18 9 sight sight NN cord-012719-5qa0e4xt 18 10 - - HYPH cord-012719-5qa0e4xt 18 11 threatening threaten VBG cord-012719-5qa0e4xt 18 12 form form NN cord-012719-5qa0e4xt 18 13 of of IN cord-012719-5qa0e4xt 18 14 glaucoma glaucoma NN cord-012719-5qa0e4xt 18 15 which which WDT cord-012719-5qa0e4xt 18 16 develops develop VBZ cord-012719-5qa0e4xt 18 17 as as IN cord-012719-5qa0e4xt 18 18 a a DT cord-012719-5qa0e4xt 18 19 result result NN cord-012719-5qa0e4xt 18 20 of of IN cord-012719-5qa0e4xt 18 21 exfoliation exfoliation NN cord-012719-5qa0e4xt 18 22 syndrome syndrome NN cord-012719-5qa0e4xt 18 23 ( ( -LRB- cord-012719-5qa0e4xt 18 24 XFS XFS NNP cord-012719-5qa0e4xt 18 25 ) ) -RRB- cord-012719-5qa0e4xt 18 26 [ [ -LRB- cord-012719-5qa0e4xt 18 27 1 1 CD cord-012719-5qa0e4xt 18 28 ] ] -RRB- cord-012719-5qa0e4xt 18 29 [ [ -LRB- cord-012719-5qa0e4xt 18 30 2 2 CD cord-012719-5qa0e4xt 18 31 ] ] -RRB- cord-012719-5qa0e4xt 18 32 [ [ -LRB- cord-012719-5qa0e4xt 18 33 3 3 CD cord-012719-5qa0e4xt 18 34 ] ] -RRB- cord-012719-5qa0e4xt 18 35 [ [ -LRB- cord-012719-5qa0e4xt 18 36 4 4 CD cord-012719-5qa0e4xt 18 37 ] ] -RRB- cord-012719-5qa0e4xt 18 38 [ [ -LRB- cord-012719-5qa0e4xt 18 39 5 5 CD cord-012719-5qa0e4xt 18 40 ] ] -RRB- cord-012719-5qa0e4xt 18 41 . . . cord-012719-5qa0e4xt 19 1 Blockage blockage NN cord-012719-5qa0e4xt 19 2 of of IN cord-012719-5qa0e4xt 19 3 the the DT cord-012719-5qa0e4xt 19 4 trabecular trabecular JJ cord-012719-5qa0e4xt 19 5 meshwork meshwork NN cord-012719-5qa0e4xt 19 6 by by IN cord-012719-5qa0e4xt 19 7 exogenous exogenous JJ cord-012719-5qa0e4xt 19 8 or or CC cord-012719-5qa0e4xt 19 9 endogenous endogenous JJ cord-012719-5qa0e4xt 19 10 exfoliative exfoliative JJ cord-012719-5qa0e4xt 19 11 materials material NNS cord-012719-5qa0e4xt 19 12 ( ( -LRB- cord-012719-5qa0e4xt 19 13 XFM XFM NNP cord-012719-5qa0e4xt 19 14 ) ) -RRB- cord-012719-5qa0e4xt 19 15 , , , cord-012719-5qa0e4xt 19 16 dysfunction dysfunction NN cord-012719-5qa0e4xt 19 17 of of IN cord-012719-5qa0e4xt 19 18 the the DT cord-012719-5qa0e4xt 19 19 trabecular trabecular JJ cord-012719-5qa0e4xt 19 20 meshwork meshwork NN cord-012719-5qa0e4xt 19 21 , , , cord-012719-5qa0e4xt 19 22 and and CC cord-012719-5qa0e4xt 19 23 concomitant concomitant JJ cord-012719-5qa0e4xt 19 24 primary primary JJ cord-012719-5qa0e4xt 19 25 open open JJ cord-012719-5qa0e4xt 19 26 - - HYPH cord-012719-5qa0e4xt 19 27 angle angle NN cord-012719-5qa0e4xt 19 28 glaucoma glaucoma NN cord-012719-5qa0e4xt 19 29 ( ( -LRB- cord-012719-5qa0e4xt 19 30 POAG POAG NNP cord-012719-5qa0e4xt 19 31 ) ) -RRB- cord-012719-5qa0e4xt 19 32 could could MD cord-012719-5qa0e4xt 19 33 cause cause VB cord-012719-5qa0e4xt 19 34 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 19 35 damage damage NN cord-012719-5qa0e4xt 19 36 [ [ -LRB- cord-012719-5qa0e4xt 19 37 1 1 CD cord-012719-5qa0e4xt 19 38 , , , cord-012719-5qa0e4xt 19 39 2 2 CD cord-012719-5qa0e4xt 19 40 ] ] -RRB- cord-012719-5qa0e4xt 19 41 . . . cord-012719-5qa0e4xt 20 1 XFG XFG NNP cord-012719-5qa0e4xt 20 2 is be VBZ cord-012719-5qa0e4xt 20 3 associated associate VBN cord-012719-5qa0e4xt 20 4 with with IN cord-012719-5qa0e4xt 20 5 a a DT cord-012719-5qa0e4xt 20 6 greater great JJR cord-012719-5qa0e4xt 20 7 mean mean VB cord-012719-5qa0e4xt 20 8 intraocular intraocular JJ cord-012719-5qa0e4xt 20 9 pressure pressure NN cord-012719-5qa0e4xt 20 10 ( ( -LRB- cord-012719-5qa0e4xt 20 11 IOP IOP NNP cord-012719-5qa0e4xt 20 12 ) ) -RRB- cord-012719-5qa0e4xt 20 13 and and CC cord-012719-5qa0e4xt 20 14 more more RBR cord-012719-5qa0e4xt 20 15 advanced advanced JJ cord-012719-5qa0e4xt 20 16 visual visual JJ cord-012719-5qa0e4xt 20 17 field field NN cord-012719-5qa0e4xt 20 18 defects defect NNS cord-012719-5qa0e4xt 20 19 at at IN cord-012719-5qa0e4xt 20 20 diagnosis diagnosis NN cord-012719-5qa0e4xt 20 21 than than IN cord-012719-5qa0e4xt 20 22 POAG POAG NNP cord-012719-5qa0e4xt 20 23 . . . cord-012719-5qa0e4xt 21 1 Consequently consequently RB cord-012719-5qa0e4xt 21 2 , , , cord-012719-5qa0e4xt 21 3 XFS XFS NNP cord-012719-5qa0e4xt 21 4 itself -PRON- PRP cord-012719-5qa0e4xt 21 5 is be VBZ cord-012719-5qa0e4xt 21 6 thought think VBN cord-012719-5qa0e4xt 21 7 to to TO cord-012719-5qa0e4xt 21 8 be be VB cord-012719-5qa0e4xt 21 9 associated associate VBN cord-012719-5qa0e4xt 21 10 with with IN cord-012719-5qa0e4xt 21 11 glaucoma glaucoma NN cord-012719-5qa0e4xt 21 12 . . . cord-012719-5qa0e4xt 22 1 XFS XFS NNP cord-012719-5qa0e4xt 22 2 is be VBZ cord-012719-5qa0e4xt 22 3 also also RB cord-012719-5qa0e4xt 22 4 associated associate VBN cord-012719-5qa0e4xt 22 5 with with IN cord-012719-5qa0e4xt 22 6 numerous numerous JJ cord-012719-5qa0e4xt 22 7 systemic systemic JJ cord-012719-5qa0e4xt 22 8 diseases disease NNS cord-012719-5qa0e4xt 22 9 , , , cord-012719-5qa0e4xt 22 10 including include VBG cord-012719-5qa0e4xt 22 11 cardiovascular cardiovascular JJ cord-012719-5qa0e4xt 22 12 disease disease NN cord-012719-5qa0e4xt 22 13 , , , cord-012719-5qa0e4xt 22 14 cerebrovascular cerebrovascular JJ cord-012719-5qa0e4xt 22 15 disease disease NN cord-012719-5qa0e4xt 22 16 , , , cord-012719-5qa0e4xt 22 17 sensorineural sensorineural JJ cord-012719-5qa0e4xt 22 18 hearing hearing NN cord-012719-5qa0e4xt 22 19 loss loss NN cord-012719-5qa0e4xt 22 20 , , , cord-012719-5qa0e4xt 22 21 and and CC cord-012719-5qa0e4xt 22 22 Alzheimer Alzheimer NNP cord-012719-5qa0e4xt 22 23 's 's POS cord-012719-5qa0e4xt 22 24 dementia dementia NN cord-012719-5qa0e4xt 22 25 [ [ -LRB- cord-012719-5qa0e4xt 22 26 3 3 CD cord-012719-5qa0e4xt 22 27 ] ] -RRB- cord-012719-5qa0e4xt 22 28 [ [ -LRB- cord-012719-5qa0e4xt 22 29 4 4 CD cord-012719-5qa0e4xt 22 30 ] ] -RRB- cord-012719-5qa0e4xt 22 31 [ [ -LRB- cord-012719-5qa0e4xt 22 32 5 5 CD cord-012719-5qa0e4xt 22 33 ] ] -RRB- cord-012719-5qa0e4xt 22 34 . . . cord-012719-5qa0e4xt 23 1 In in IN cord-012719-5qa0e4xt 23 2 particular particular JJ cord-012719-5qa0e4xt 23 3 , , , cord-012719-5qa0e4xt 23 4 XFS XFS NNP cord-012719-5qa0e4xt 23 5 seems seem VBZ cord-012719-5qa0e4xt 23 6 to to TO cord-012719-5qa0e4xt 23 7 widely widely RB cord-012719-5qa0e4xt 23 8 affect affect VB cord-012719-5qa0e4xt 23 9 various various JJ cord-012719-5qa0e4xt 23 10 ocular ocular JJ cord-012719-5qa0e4xt 23 11 vasculatures vasculature NNS cord-012719-5qa0e4xt 23 12 , , , cord-012719-5qa0e4xt 23 13 including include VBG cord-012719-5qa0e4xt 23 14 the the DT cord-012719-5qa0e4xt 23 15 ophthalmic ophthalmic JJ cord-012719-5qa0e4xt 23 16 artery artery NN cord-012719-5qa0e4xt 23 17 , , , cord-012719-5qa0e4xt 23 18 ciliary ciliary NN cord-012719-5qa0e4xt 23 19 circulation circulation NN cord-012719-5qa0e4xt 23 20 , , , cord-012719-5qa0e4xt 23 21 iris iris NN cord-012719-5qa0e4xt 23 22 vessels vessel NNS cord-012719-5qa0e4xt 23 23 , , , cord-012719-5qa0e4xt 23 24 and and CC cord-012719-5qa0e4xt 23 25 central central JJ cord-012719-5qa0e4xt 23 26 retinal retinal JJ cord-012719-5qa0e4xt 23 27 vessels vessel NNS cord-012719-5qa0e4xt 23 28 [ [ -LRB- cord-012719-5qa0e4xt 23 29 6 6 CD cord-012719-5qa0e4xt 23 30 , , , cord-012719-5qa0e4xt 23 31 7 7 CD cord-012719-5qa0e4xt 23 32 ] ] -RRB- cord-012719-5qa0e4xt 23 33 . . . cord-012719-5qa0e4xt 24 1 Previous previous JJ cord-012719-5qa0e4xt 24 2 studies study NNS cord-012719-5qa0e4xt 24 3 using use VBG cord-012719-5qa0e4xt 24 4 color color NN cord-012719-5qa0e4xt 24 5 Doppler Doppler NNP cord-012719-5qa0e4xt 24 6 imaging imaging NN cord-012719-5qa0e4xt 24 7 have have VBP cord-012719-5qa0e4xt 24 8 reported report VBN cord-012719-5qa0e4xt 24 9 reduced reduce VBN cord-012719-5qa0e4xt 24 10 blood blood NN cord-012719-5qa0e4xt 24 11 - - HYPH cord-012719-5qa0e4xt 24 12 flow flow NN cord-012719-5qa0e4xt 24 13 velocities velocity NNS cord-012719-5qa0e4xt 24 14 and and CC cord-012719-5qa0e4xt 24 15 increased increase VBN cord-012719-5qa0e4xt 24 16 resistivity resistivity NN cord-012719-5qa0e4xt 24 17 in in IN cord-012719-5qa0e4xt 24 18 the the DT cord-012719-5qa0e4xt 24 19 ophthalmic ophthalmic JJ cord-012719-5qa0e4xt 24 20 artery artery NN cord-012719-5qa0e4xt 24 21 , , , cord-012719-5qa0e4xt 24 22 central central JJ cord-012719-5qa0e4xt 24 23 retinal retinal JJ cord-012719-5qa0e4xt 24 24 artery artery NN cord-012719-5qa0e4xt 24 25 , , , cord-012719-5qa0e4xt 24 26 and and CC cord-012719-5qa0e4xt 24 27 short short JJ cord-012719-5qa0e4xt 24 28 posterior posterior JJ cord-012719-5qa0e4xt 24 29 ciliary ciliary NN cord-012719-5qa0e4xt 24 30 artery artery NN cord-012719-5qa0e4xt 24 31 in in IN cord-012719-5qa0e4xt 24 32 XFS XFS NNP cord-012719-5qa0e4xt 24 33 [ [ -LRB- cord-012719-5qa0e4xt 24 34 8 8 CD cord-012719-5qa0e4xt 24 35 , , , cord-012719-5qa0e4xt 24 36 9 9 CD cord-012719-5qa0e4xt 24 37 ] ] -RRB- cord-012719-5qa0e4xt 24 38 . . . cord-012719-5qa0e4xt 25 1 Besides besides IN cord-012719-5qa0e4xt 25 2 ocular ocular JJ cord-012719-5qa0e4xt 25 3 vasculature vasculature NN cord-012719-5qa0e4xt 25 4 , , , cord-012719-5qa0e4xt 25 5 some some DT cord-012719-5qa0e4xt 25 6 studies study NNS cord-012719-5qa0e4xt 25 7 have have VBP cord-012719-5qa0e4xt 25 8 reported report VBN cord-012719-5qa0e4xt 25 9 reduced reduce VBN cord-012719-5qa0e4xt 25 10 retrobulbar retrobulbar NN cord-012719-5qa0e4xt 25 11 blood blood NN cord-012719-5qa0e4xt 25 12 flow flow NN cord-012719-5qa0e4xt 25 13 and and CC cord-012719-5qa0e4xt 25 14 ipsilateral ipsilateral JJ cord-012719-5qa0e4xt 25 15 carotid carotid JJ cord-012719-5qa0e4xt 25 16 blood blood NN cord-012719-5qa0e4xt 25 17 flow flow NN cord-012719-5qa0e4xt 25 18 in in IN cord-012719-5qa0e4xt 25 19 the the DT cord-012719-5qa0e4xt 25 20 XFSaffected xfsaffected JJ cord-012719-5qa0e4xt 25 21 eye eye NN cord-012719-5qa0e4xt 25 22 [ [ -LRB- cord-012719-5qa0e4xt 25 23 10 10 CD cord-012719-5qa0e4xt 25 24 , , , cord-012719-5qa0e4xt 25 25 11 11 CD cord-012719-5qa0e4xt 25 26 ] ] -RRB- cord-012719-5qa0e4xt 25 27 . . . cord-012719-5qa0e4xt 26 1 These these DT cord-012719-5qa0e4xt 26 2 hemodynamic hemodynamic JJ cord-012719-5qa0e4xt 26 3 changes change NNS cord-012719-5qa0e4xt 26 4 may may MD cord-012719-5qa0e4xt 26 5 result result VB cord-012719-5qa0e4xt 26 6 in in IN cord-012719-5qa0e4xt 26 7 retinal retinal JJ cord-012719-5qa0e4xt 26 8 nerve nerve NN cord-012719-5qa0e4xt 26 9 fiber fiber NN cord-012719-5qa0e4xt 26 10 thinning thinning NN cord-012719-5qa0e4xt 26 11 and and CC cord-012719-5qa0e4xt 26 12 ganglion ganglion NN cord-012719-5qa0e4xt 26 13 cell cell NN cord-012719-5qa0e4xt 26 14 layer layer NN cord-012719-5qa0e4xt 26 15 changes change NNS cord-012719-5qa0e4xt 26 16 , , , cord-012719-5qa0e4xt 26 17 even even RB cord-012719-5qa0e4xt 26 18 in in IN cord-012719-5qa0e4xt 26 19 eyes eye NNS cord-012719-5qa0e4xt 26 20 without without IN cord-012719-5qa0e4xt 26 21 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 26 22 damage damage NN cord-012719-5qa0e4xt 26 23 [ [ -LRB- cord-012719-5qa0e4xt 26 24 12 12 CD cord-012719-5qa0e4xt 26 25 ] ] -RRB- cord-012719-5qa0e4xt 26 26 . . . cord-012719-5qa0e4xt 27 1 Assessment assessment NN cord-012719-5qa0e4xt 27 2 of of IN cord-012719-5qa0e4xt 27 3 the the DT cord-012719-5qa0e4xt 27 4 macula macula NN cord-012719-5qa0e4xt 27 5 allows allow VBZ cord-012719-5qa0e4xt 27 6 investigation investigation NN cord-012719-5qa0e4xt 27 7 of of IN cord-012719-5qa0e4xt 27 8 the the DT cord-012719-5qa0e4xt 27 9 clinical clinical JJ cord-012719-5qa0e4xt 27 10 impact impact NN cord-012719-5qa0e4xt 27 11 of of IN cord-012719-5qa0e4xt 27 12 the the DT cord-012719-5qa0e4xt 27 13 diagnosis diagnosis NN cord-012719-5qa0e4xt 27 14 of of IN cord-012719-5qa0e4xt 27 15 early early JJ cord-012719-5qa0e4xt 27 16 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 27 17 change change NN cord-012719-5qa0e4xt 27 18 [ [ -LRB- cord-012719-5qa0e4xt 27 19 13 13 CD cord-012719-5qa0e4xt 27 20 ] ] -RRB- cord-012719-5qa0e4xt 27 21 . . . cord-012719-5qa0e4xt 28 1 About about RB cord-012719-5qa0e4xt 28 2 50 50 CD cord-012719-5qa0e4xt 28 3 % % NN cord-012719-5qa0e4xt 28 4 of of IN cord-012719-5qa0e4xt 28 5 retinal retinal JJ cord-012719-5qa0e4xt 28 6 ganglion ganglion NN cord-012719-5qa0e4xt 28 7 cells cell NNS cord-012719-5qa0e4xt 28 8 are be VBP cord-012719-5qa0e4xt 28 9 located locate VBN cord-012719-5qa0e4xt 28 10 in in IN cord-012719-5qa0e4xt 28 11 the the DT cord-012719-5qa0e4xt 28 12 macula macula NN cord-012719-5qa0e4xt 28 13 [ [ -LRB- cord-012719-5qa0e4xt 28 14 14 14 CD cord-012719-5qa0e4xt 28 15 ] ] -RRB- cord-012719-5qa0e4xt 28 16 . . . cord-012719-5qa0e4xt 29 1 In in IN cord-012719-5qa0e4xt 29 2 this this DT cord-012719-5qa0e4xt 29 3 context context NN cord-012719-5qa0e4xt 29 4 , , , cord-012719-5qa0e4xt 29 5 evaluation evaluation NN cord-012719-5qa0e4xt 29 6 of of IN cord-012719-5qa0e4xt 29 7 both both CC cord-012719-5qa0e4xt 29 8 the the DT cord-012719-5qa0e4xt 29 9 ganglion ganglion NN cord-012719-5qa0e4xt 29 10 cell cell NN cord-012719-5qa0e4xt 29 11 complex complex NN cord-012719-5qa0e4xt 29 12 ( ( -LRB- cord-012719-5qa0e4xt 29 13 GCC GCC NNP cord-012719-5qa0e4xt 29 14 , , , cord-012719-5qa0e4xt 29 15 a a DT cord-012719-5qa0e4xt 29 16 combination combination NN cord-012719-5qa0e4xt 29 17 of of IN cord-012719-5qa0e4xt 29 18 the the DT cord-012719-5qa0e4xt 29 19 nerve nerve NN cord-012719-5qa0e4xt 29 20 fiber fiber NN cord-012719-5qa0e4xt 29 21 layer layer NN cord-012719-5qa0e4xt 29 22 , , , cord-012719-5qa0e4xt 29 23 ganglion ganglion NN cord-012719-5qa0e4xt 29 24 cell cell NN cord-012719-5qa0e4xt 29 25 layer layer NN cord-012719-5qa0e4xt 29 26 , , , cord-012719-5qa0e4xt 29 27 and and CC cord-012719-5qa0e4xt 29 28 inner inner JJ cord-012719-5qa0e4xt 29 29 plexiform plexiform NNS cord-012719-5qa0e4xt 29 30 layer layer NN cord-012719-5qa0e4xt 29 31 ) ) -RRB- cord-012719-5qa0e4xt 29 32 and and CC cord-012719-5qa0e4xt 29 33 circumpapillary circumpapillary NNP cord-012719-5qa0e4xt 29 34 retinal retinal JJ cord-012719-5qa0e4xt 29 35 nerve nerve NN cord-012719-5qa0e4xt 29 36 fiber fiber NN cord-012719-5qa0e4xt 29 37 layer layer NN cord-012719-5qa0e4xt 29 38 ( ( -LRB- cord-012719-5qa0e4xt 29 39 cpRNFL cprnfl NN cord-012719-5qa0e4xt 29 40 ) ) -RRB- cord-012719-5qa0e4xt 29 41 is be VBZ cord-012719-5qa0e4xt 29 42 important important JJ cord-012719-5qa0e4xt 29 43 because because IN cord-012719-5qa0e4xt 29 44 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 29 45 retinal retinal JJ cord-012719-5qa0e4xt 29 46 atrophy atrophy NN cord-012719-5qa0e4xt 29 47 mostly mostly RB cord-012719-5qa0e4xt 29 48 affects affect VBZ cord-012719-5qa0e4xt 29 49 the the DT cord-012719-5qa0e4xt 29 50 RNFL RNFL NNP cord-012719-5qa0e4xt 29 51 and and CC cord-012719-5qa0e4xt 29 52 GCC GCC NNP cord-012719-5qa0e4xt 29 53 . . . cord-012719-5qa0e4xt 30 1 However however RB cord-012719-5qa0e4xt 30 2 , , , cord-012719-5qa0e4xt 30 3 few few JJ cord-012719-5qa0e4xt 30 4 studies study NNS cord-012719-5qa0e4xt 30 5 have have VBP cord-012719-5qa0e4xt 30 6 compared compare VBN cord-012719-5qa0e4xt 30 7 the the DT cord-012719-5qa0e4xt 30 8 RNFL RNFL NNP cord-012719-5qa0e4xt 30 9 and and CC cord-012719-5qa0e4xt 30 10 GCC GCC NNP cord-012719-5qa0e4xt 30 11 thicknesses thickness NNS cord-012719-5qa0e4xt 30 12 in in IN cord-012719-5qa0e4xt 30 13 XFS xfs JJ cord-012719-5qa0e4xt 30 14 patients patient NNS cord-012719-5qa0e4xt 30 15 without without IN cord-012719-5qa0e4xt 30 16 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 30 17 damage damage NN cord-012719-5qa0e4xt 30 18 and and CC cord-012719-5qa0e4xt 30 19 healthy healthy JJ cord-012719-5qa0e4xt 30 20 controls control NNS cord-012719-5qa0e4xt 30 21 [ [ -LRB- cord-012719-5qa0e4xt 30 22 12 12 CD cord-012719-5qa0e4xt 30 23 , , , cord-012719-5qa0e4xt 30 24 15 15 CD cord-012719-5qa0e4xt 30 25 ] ] -RRB- cord-012719-5qa0e4xt 30 26 , , , cord-012719-5qa0e4xt 30 27 and and CC cord-012719-5qa0e4xt 30 28 no no DT cord-012719-5qa0e4xt 30 29 studies study NNS cord-012719-5qa0e4xt 30 30 in in IN cord-012719-5qa0e4xt 30 31 an an DT cord-012719-5qa0e4xt 30 32 Asian asian JJ cord-012719-5qa0e4xt 30 33 population population NN cord-012719-5qa0e4xt 30 34 have have VBP cord-012719-5qa0e4xt 30 35 been be VBN cord-012719-5qa0e4xt 30 36 reported report VBN cord-012719-5qa0e4xt 30 37 to to IN cord-012719-5qa0e4xt 30 38 date date NN cord-012719-5qa0e4xt 30 39 . . . cord-012719-5qa0e4xt 31 1 Thus thus RB cord-012719-5qa0e4xt 31 2 , , , cord-012719-5qa0e4xt 31 3 the the DT cord-012719-5qa0e4xt 31 4 purpose purpose NN cord-012719-5qa0e4xt 31 5 of of IN cord-012719-5qa0e4xt 31 6 this this DT cord-012719-5qa0e4xt 31 7 study study NN cord-012719-5qa0e4xt 31 8 was be VBD cord-012719-5qa0e4xt 31 9 to to TO cord-012719-5qa0e4xt 31 10 evaluate evaluate VB cord-012719-5qa0e4xt 31 11 automated automate VBN cord-012719-5qa0e4xt 31 12 measurements measurement NNS cord-012719-5qa0e4xt 31 13 of of IN cord-012719-5qa0e4xt 31 14 cpRNFL cpRNFL NNS cord-012719-5qa0e4xt 31 15 and and CC cord-012719-5qa0e4xt 31 16 GCC GCC NNP cord-012719-5qa0e4xt 31 17 thickness thickness NN cord-012719-5qa0e4xt 31 18 , , , cord-012719-5qa0e4xt 31 19 using use VBG cord-012719-5qa0e4xt 31 20 the the DT cord-012719-5qa0e4xt 31 21 RT RT NNP cord-012719-5qa0e4xt 31 22 - - HYPH cord-012719-5qa0e4xt 31 23 Vue Vue NNP cord-012719-5qa0e4xt 31 24 100 100 CD cord-012719-5qa0e4xt 31 25 ( ( -LRB- cord-012719-5qa0e4xt 31 26 Optovue Optovue NNP cord-012719-5qa0e4xt 31 27 , , , cord-012719-5qa0e4xt 31 28 Fremont Fremont NNP cord-012719-5qa0e4xt 31 29 , , , cord-012719-5qa0e4xt 31 30 CA CA NNP cord-012719-5qa0e4xt 31 31 ) ) -RRB- cord-012719-5qa0e4xt 31 32 SD SD NNP cord-012719-5qa0e4xt 31 33 - - HYPH cord-012719-5qa0e4xt 31 34 OCT OCT NNP cord-012719-5qa0e4xt 31 35 system system NN cord-012719-5qa0e4xt 31 36 , , , cord-012719-5qa0e4xt 31 37 in in IN cord-012719-5qa0e4xt 31 38 patients patient NNS cord-012719-5qa0e4xt 31 39 with with IN cord-012719-5qa0e4xt 31 40 unilateral unilateral JJ cord-012719-5qa0e4xt 31 41 XFS xfs NN cord-012719-5qa0e4xt 31 42 without without IN cord-012719-5qa0e4xt 31 43 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 31 44 damage damage NN cord-012719-5qa0e4xt 31 45 . . . cord-012719-5qa0e4xt 32 1 This this DT cord-012719-5qa0e4xt 32 2 prospective prospective JJ cord-012719-5qa0e4xt 32 3 cross cross JJ cord-012719-5qa0e4xt 32 4 - - JJ cord-012719-5qa0e4xt 32 5 sectional sectional JJ cord-012719-5qa0e4xt 32 6 study study NN cord-012719-5qa0e4xt 32 7 was be VBD cord-012719-5qa0e4xt 32 8 approved approve VBN cord-012719-5qa0e4xt 32 9 by by IN cord-012719-5qa0e4xt 32 10 the the DT cord-012719-5qa0e4xt 32 11 institutional institutional NNP cord-012719-5qa0e4xt 32 12 review review NNP cord-012719-5qa0e4xt 32 13 board board NN cord-012719-5qa0e4xt 32 14 of of IN cord-012719-5qa0e4xt 32 15 Daegu Daegu NNP cord-012719-5qa0e4xt 32 16 Veterans Veterans NNPS cord-012719-5qa0e4xt 32 17 Health Health NNP cord-012719-5qa0e4xt 32 18 Service Service NNP cord-012719-5qa0e4xt 32 19 Medical Medical NNP cord-012719-5qa0e4xt 32 20 Center Center NNP cord-012719-5qa0e4xt 32 21 . . . cord-012719-5qa0e4xt 33 1 All all DT cord-012719-5qa0e4xt 33 2 participants participant NNS cord-012719-5qa0e4xt 33 3 gave give VBD cord-012719-5qa0e4xt 33 4 informed informed JJ cord-012719-5qa0e4xt 33 5 consent consent NN cord-012719-5qa0e4xt 33 6 to to TO cord-012719-5qa0e4xt 33 7 participate participate VB cord-012719-5qa0e4xt 33 8 . . . cord-012719-5qa0e4xt 34 1 This this DT cord-012719-5qa0e4xt 34 2 study study NN cord-012719-5qa0e4xt 34 3 was be VBD cord-012719-5qa0e4xt 34 4 performed perform VBN cord-012719-5qa0e4xt 34 5 in in IN cord-012719-5qa0e4xt 34 6 accordance accordance NN cord-012719-5qa0e4xt 34 7 with with IN cord-012719-5qa0e4xt 34 8 the the DT cord-012719-5qa0e4xt 34 9 tenets tenet NNS cord-012719-5qa0e4xt 34 10 of of IN cord-012719-5qa0e4xt 34 11 the the DT cord-012719-5qa0e4xt 34 12 Declaration Declaration NNP cord-012719-5qa0e4xt 34 13 of of IN cord-012719-5qa0e4xt 34 14 Helsinki Helsinki NNP cord-012719-5qa0e4xt 34 15 . . . cord-012719-5qa0e4xt 35 1 The the DT cord-012719-5qa0e4xt 35 2 subjects subject NNS cord-012719-5qa0e4xt 35 3 were be VBD cord-012719-5qa0e4xt 35 4 enrolled enrol VBN cord-012719-5qa0e4xt 35 5 and and CC cord-012719-5qa0e4xt 35 6 investigated investigate VBN cord-012719-5qa0e4xt 35 7 between between IN cord-012719-5qa0e4xt 35 8 January January NNP cord-012719-5qa0e4xt 35 9 2015 2015 CD cord-012719-5qa0e4xt 35 10 and and CC cord-012719-5qa0e4xt 35 11 December December NNP cord-012719-5qa0e4xt 35 12 2015 2015 CD cord-012719-5qa0e4xt 35 13 at at IN cord-012719-5qa0e4xt 35 14 Daegu Daegu NNP cord-012719-5qa0e4xt 35 15 Veterans Veterans NNPS cord-012719-5qa0e4xt 35 16 Health Health NNP cord-012719-5qa0e4xt 35 17 Service Service NNP cord-012719-5qa0e4xt 35 18 Medical Medical NNP cord-012719-5qa0e4xt 35 19 Center Center NNP cord-012719-5qa0e4xt 35 20 in in IN cord-012719-5qa0e4xt 35 21 South South NNP cord-012719-5qa0e4xt 35 22 Korea Korea NNP cord-012719-5qa0e4xt 35 23 . . . cord-012719-5qa0e4xt 36 1 A a DT cord-012719-5qa0e4xt 36 2 total total NN cord-012719-5qa0e4xt 36 3 of of IN cord-012719-5qa0e4xt 36 4 54 54 CD cord-012719-5qa0e4xt 36 5 eyes eye NNS cord-012719-5qa0e4xt 36 6 of of IN cord-012719-5qa0e4xt 36 7 27 27 CD cord-012719-5qa0e4xt 36 8 unilateral unilateral JJ cord-012719-5qa0e4xt 36 9 XFS xfs NN cord-012719-5qa0e4xt 36 10 patients patient NNS cord-012719-5qa0e4xt 36 11 ( ( -LRB- cord-012719-5qa0e4xt 36 12 the the DT cord-012719-5qa0e4xt 36 13 affected affected JJ cord-012719-5qa0e4xt 36 14 and and CC cord-012719-5qa0e4xt 36 15 the the DT cord-012719-5qa0e4xt 36 16 fellow fellow JJ cord-012719-5qa0e4xt 36 17 eyes eye NNS cord-012719-5qa0e4xt 36 18 ) ) -RRB- cord-012719-5qa0e4xt 36 19 and and CC cord-012719-5qa0e4xt 36 20 27 27 CD cord-012719-5qa0e4xt 36 21 eyes eye NNS cord-012719-5qa0e4xt 36 22 of of IN cord-012719-5qa0e4xt 36 23 27 27 CD cord-012719-5qa0e4xt 36 24 age age NN cord-012719-5qa0e4xt 36 25 - - HYPH cord-012719-5qa0e4xt 36 26 matched match VBN cord-012719-5qa0e4xt 36 27 control control NN cord-012719-5qa0e4xt 36 28 subjects subject NNS cord-012719-5qa0e4xt 36 29 ( ( -LRB- cord-012719-5qa0e4xt 36 30 the the DT cord-012719-5qa0e4xt 36 31 right right JJ cord-012719-5qa0e4xt 36 32 eye eye NN cord-012719-5qa0e4xt 36 33 ) ) -RRB- cord-012719-5qa0e4xt 36 34 were be VBD cord-012719-5qa0e4xt 36 35 included include VBN cord-012719-5qa0e4xt 36 36 in in IN cord-012719-5qa0e4xt 36 37 the the DT cord-012719-5qa0e4xt 36 38 study study NN cord-012719-5qa0e4xt 36 39 . . . cord-012719-5qa0e4xt 37 1 Unilateral unilateral JJ cord-012719-5qa0e4xt 37 2 XFS XFS NNP cord-012719-5qa0e4xt 37 3 was be VBD cord-012719-5qa0e4xt 37 4 defined define VBN cord-012719-5qa0e4xt 37 5 as as IN cord-012719-5qa0e4xt 37 6 having have VBG cord-012719-5qa0e4xt 37 7 one one CD cord-012719-5qa0e4xt 37 8 eye eye NN cord-012719-5qa0e4xt 37 9 with with IN cord-012719-5qa0e4xt 37 10 XFS XFS NNP cord-012719-5qa0e4xt 37 11 , , , cord-012719-5qa0e4xt 37 12 diagnosed diagnose VBN cord-012719-5qa0e4xt 37 13 using use VBG cord-012719-5qa0e4xt 37 14 slit slit JJ cord-012719-5qa0e4xt 37 15 - - HYPH cord-012719-5qa0e4xt 37 16 lamp lamp NN cord-012719-5qa0e4xt 37 17 biomicroscopy biomicroscopy NN cord-012719-5qa0e4xt 37 18 , , , cord-012719-5qa0e4xt 37 19 tonometry tonometry NNP cord-012719-5qa0e4xt 37 20 , , , cord-012719-5qa0e4xt 37 21 and and CC cord-012719-5qa0e4xt 37 22 dilated dilated JJ cord-012719-5qa0e4xt 37 23 fundus fundus JJ cord-012719-5qa0e4xt 37 24 examination examination NN cord-012719-5qa0e4xt 37 25 , , , cord-012719-5qa0e4xt 37 26 and and CC cord-012719-5qa0e4xt 37 27 a a DT cord-012719-5qa0e4xt 37 28 fellow fellow JJ cord-012719-5qa0e4xt 37 29 eye eye NN cord-012719-5qa0e4xt 37 30 without without IN cord-012719-5qa0e4xt 37 31 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 37 32 damage damage NN cord-012719-5qa0e4xt 37 33 or or CC cord-012719-5qa0e4xt 37 34 retinal retinal JJ cord-012719-5qa0e4xt 37 35 diseases disease NNS cord-012719-5qa0e4xt 37 36 . . . cord-012719-5qa0e4xt 38 1 XFS XFS NNP cord-012719-5qa0e4xt 38 2 was be VBD cord-012719-5qa0e4xt 38 3 defined define VBN cord-012719-5qa0e4xt 38 4 as as IN cord-012719-5qa0e4xt 38 5 follows follow VBZ cord-012719-5qa0e4xt 38 6 [ [ -LRB- cord-012719-5qa0e4xt 38 7 2 2 CD cord-012719-5qa0e4xt 38 8 ] ] -RRB- cord-012719-5qa0e4xt 38 9 : : : cord-012719-5qa0e4xt 38 10 ( ( -LRB- cord-012719-5qa0e4xt 38 11 1 1 LS cord-012719-5qa0e4xt 38 12 ) ) -RRB- cord-012719-5qa0e4xt 38 13 presence presence NN cord-012719-5qa0e4xt 38 14 of of IN cord-012719-5qa0e4xt 38 15 characteristic characteristic JJ cord-012719-5qa0e4xt 38 16 fibrillar fibrillar JJ cord-012719-5qa0e4xt 38 17 exfoliation exfoliation NN cord-012719-5qa0e4xt 38 18 materials material NNS cord-012719-5qa0e4xt 38 19 at at IN cord-012719-5qa0e4xt 38 20 the the DT cord-012719-5qa0e4xt 38 21 pupillary pupillary JJ cord-012719-5qa0e4xt 38 22 border border NN cord-012719-5qa0e4xt 38 23 or or CC cord-012719-5qa0e4xt 38 24 on on IN cord-012719-5qa0e4xt 38 25 the the DT cord-012719-5qa0e4xt 38 26 anterior anterior JJ cord-012719-5qa0e4xt 38 27 capsule capsule NN cord-012719-5qa0e4xt 38 28 after after IN cord-012719-5qa0e4xt 38 29 pupillary pupillary JJ cord-012719-5qa0e4xt 38 30 dilation dilation NN cord-012719-5qa0e4xt 38 31 , , , cord-012719-5qa0e4xt 38 32 ( ( -LRB- cord-012719-5qa0e4xt 38 33 2 2 LS cord-012719-5qa0e4xt 38 34 ) ) -RRB- cord-012719-5qa0e4xt 38 35 IOP IOP NNP cord-012719-5qa0e4xt 38 36 < < XX cord-012719-5qa0e4xt 38 37 21 21 CD cord-012719-5qa0e4xt 38 38 mmHg mmHg NNS cord-012719-5qa0e4xt 38 39 , , , cord-012719-5qa0e4xt 38 40 without without IN cord-012719-5qa0e4xt 38 41 antiglaucoma antiglaucoma NNP cord-012719-5qa0e4xt 38 42 treatment treatment NN cord-012719-5qa0e4xt 38 43 , , , cord-012719-5qa0e4xt 38 44 ( ( -LRB- cord-012719-5qa0e4xt 38 45 3 3 LS cord-012719-5qa0e4xt 38 46 ) ) -RRB- cord-012719-5qa0e4xt 38 47 no no DT cord-012719-5qa0e4xt 38 48 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 38 49 optic optic JJ cord-012719-5qa0e4xt 38 50 nerve nerve NN cord-012719-5qa0e4xt 38 51 head head NN cord-012719-5qa0e4xt 38 52 ( ( -LRB- cord-012719-5qa0e4xt 38 53 ONH ONH NNP cord-012719-5qa0e4xt 38 54 ) ) -RRB- cord-012719-5qa0e4xt 38 55 changes change NNS cord-012719-5qa0e4xt 38 56 confirmed confirm VBN cord-012719-5qa0e4xt 38 57 by by IN cord-012719-5qa0e4xt 38 58 dilated dilated JJ cord-012719-5qa0e4xt 38 59 fundus fundus NN cord-012719-5qa0e4xt 38 60 exam exam NN cord-012719-5qa0e4xt 38 61 and and CC cord-012719-5qa0e4xt 38 62 SD SD NNP cord-012719-5qa0e4xt 38 63 - - HYPH cord-012719-5qa0e4xt 38 64 OCT OCT NNP cord-012719-5qa0e4xt 38 65 , , , cord-012719-5qa0e4xt 38 66 ( ( -LRB- cord-012719-5qa0e4xt 38 67 4 4 LS cord-012719-5qa0e4xt 38 68 ) ) -RRB- cord-012719-5qa0e4xt 38 69 open open JJ cord-012719-5qa0e4xt 38 70 - - HYPH cord-012719-5qa0e4xt 38 71 angle angle NN cord-012719-5qa0e4xt 38 72 status status NN cord-012719-5qa0e4xt 38 73 on on IN cord-012719-5qa0e4xt 38 74 gonioscopic gonioscopic JJ cord-012719-5qa0e4xt 38 75 examination examination NN cord-012719-5qa0e4xt 38 76 , , , cord-012719-5qa0e4xt 38 77 without without IN cord-012719-5qa0e4xt 38 78 visual visual JJ cord-012719-5qa0e4xt 38 79 field field NN cord-012719-5qa0e4xt 38 80 defects defect NNS cord-012719-5qa0e4xt 38 81 confirmed confirm VBN cord-012719-5qa0e4xt 38 82 by by IN cord-012719-5qa0e4xt 38 83 automated automate VBN cord-012719-5qa0e4xt 38 84 perimetry perimetry NN cord-012719-5qa0e4xt 38 85 in in IN cord-012719-5qa0e4xt 38 86 all all DT cord-012719-5qa0e4xt 38 87 XFS xfs JJ cord-012719-5qa0e4xt 38 88 patients patient NNS cord-012719-5qa0e4xt 38 89 . . . cord-012719-5qa0e4xt 39 1 The the DT cord-012719-5qa0e4xt 39 2 control control NN cord-012719-5qa0e4xt 39 3 group group NN cord-012719-5qa0e4xt 39 4 was be VBD cord-012719-5qa0e4xt 39 5 defined define VBN cord-012719-5qa0e4xt 39 6 as as IN cord-012719-5qa0e4xt 39 7 those those DT cord-012719-5qa0e4xt 39 8 without without IN cord-012719-5qa0e4xt 39 9 a a DT cord-012719-5qa0e4xt 39 10 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 39 11 ONH ONH NNP cord-012719-5qa0e4xt 39 12 or or CC cord-012719-5qa0e4xt 39 13 RNFL RNFL NNP cord-012719-5qa0e4xt 39 14 defect defect NN cord-012719-5qa0e4xt 39 15 , , , cord-012719-5qa0e4xt 39 16 visual visual JJ cord-012719-5qa0e4xt 39 17 field field NN cord-012719-5qa0e4xt 39 18 defect defect NN cord-012719-5qa0e4xt 39 19 , , , cord-012719-5qa0e4xt 39 20 or or CC cord-012719-5qa0e4xt 39 21 other other JJ cord-012719-5qa0e4xt 39 22 retinal retinal JJ cord-012719-5qa0e4xt 39 23 diseases disease NNS cord-012719-5qa0e4xt 39 24 in in IN cord-012719-5qa0e4xt 39 25 either either DT cord-012719-5qa0e4xt 39 26 eye eye NN cord-012719-5qa0e4xt 39 27 . . . cord-012719-5qa0e4xt 40 1 The the DT cord-012719-5qa0e4xt 40 2 exclusion exclusion NN cord-012719-5qa0e4xt 40 3 criteria criterion NNS cord-012719-5qa0e4xt 40 4 were be VBD cord-012719-5qa0e4xt 40 5 as as IN cord-012719-5qa0e4xt 40 6 follows follow VBZ cord-012719-5qa0e4xt 40 7 : : : cord-012719-5qa0e4xt 41 1 ( ( -LRB- cord-012719-5qa0e4xt 41 2 1 1 LS cord-012719-5qa0e4xt 41 3 ) ) -RRB- cord-012719-5qa0e4xt 41 4 patients patient NNS cord-012719-5qa0e4xt 41 5 older old JJR cord-012719-5qa0e4xt 41 6 than than IN cord-012719-5qa0e4xt 41 7 80 80 CD cord-012719-5qa0e4xt 41 8 years year NNS cord-012719-5qa0e4xt 41 9 or or CC cord-012719-5qa0e4xt 41 10 younger young JJR cord-012719-5qa0e4xt 41 11 than than IN cord-012719-5qa0e4xt 41 12 40 40 CD cord-012719-5qa0e4xt 41 13 years year NNS cord-012719-5qa0e4xt 41 14 ; ; , cord-012719-5qa0e4xt 41 15 ( ( -LRB- cord-012719-5qa0e4xt 41 16 2 2 LS cord-012719-5qa0e4xt 41 17 ) ) -RRB- cord-012719-5qa0e4xt 41 18 eyes eye NNS cord-012719-5qa0e4xt 41 19 with with IN cord-012719-5qa0e4xt 41 20 a a DT cord-012719-5qa0e4xt 41 21 refractive refractive JJ cord-012719-5qa0e4xt 41 22 error error NN cord-012719-5qa0e4xt 41 23 of of IN cord-012719-5qa0e4xt 41 24 less less JJR cord-012719-5qa0e4xt 41 25 than than IN cord-012719-5qa0e4xt 41 26 −6 −6 NNP cord-012719-5qa0e4xt 41 27 diopters diopter NNS cord-012719-5qa0e4xt 41 28 or or CC cord-012719-5qa0e4xt 41 29 more more JJR cord-012719-5qa0e4xt 41 30 than than IN cord-012719-5qa0e4xt 41 31 +4 +4 JJ cord-012719-5qa0e4xt 41 32 diopters diopter NNS cord-012719-5qa0e4xt 41 33 ; ; , cord-012719-5qa0e4xt 41 34 ( ( -LRB- cord-012719-5qa0e4xt 41 35 3 3 LS cord-012719-5qa0e4xt 41 36 ) ) -RRB- cord-012719-5qa0e4xt 41 37 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 41 38 changes change NNS cord-012719-5qa0e4xt 41 39 including include VBG cord-012719-5qa0e4xt 41 40 glaucomatous glaucomatous NNP cord-012719-5qa0e4xt 41 41 ONH ONH NNP cord-012719-5qa0e4xt 41 42 changes change NNS cord-012719-5qa0e4xt 41 43 and and CC cord-012719-5qa0e4xt 41 44 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 41 45 visual visual JJ cord-012719-5qa0e4xt 41 46 field field NN cord-012719-5qa0e4xt 41 47 defects defect NNS cord-012719-5qa0e4xt 41 48 ; ; , cord-012719-5qa0e4xt 41 49 ( ( -LRB- cord-012719-5qa0e4xt 41 50 4 4 LS cord-012719-5qa0e4xt 41 51 ) ) -RRB- cord-012719-5qa0e4xt 41 52 a a DT cord-012719-5qa0e4xt 41 53 history history NN cord-012719-5qa0e4xt 41 54 of of IN cord-012719-5qa0e4xt 41 55 antiglaucoma antiglaucoma NNP cord-012719-5qa0e4xt 41 56 treatment treatment NN cord-012719-5qa0e4xt 41 57 , , , cord-012719-5qa0e4xt 41 58 including include VBG cord-012719-5qa0e4xt 41 59 medication medication NN cord-012719-5qa0e4xt 41 60 and and CC cord-012719-5qa0e4xt 41 61 laser laser NN cord-012719-5qa0e4xt 41 62 treatment treatment NN cord-012719-5qa0e4xt 41 63 ; ; : cord-012719-5qa0e4xt 41 64 ( ( -LRB- cord-012719-5qa0e4xt 41 65 5 5 LS cord-012719-5qa0e4xt 41 66 ) ) -RRB- cord-012719-5qa0e4xt 41 67 media medium NNS cord-012719-5qa0e4xt 41 68 opacity opacity NN cord-012719-5qa0e4xt 41 69 that that WDT cord-012719-5qa0e4xt 41 70 reduced reduce VBD cord-012719-5qa0e4xt 41 71 the the DT cord-012719-5qa0e4xt 41 72 image image NN cord-012719-5qa0e4xt 41 73 quality quality NN cord-012719-5qa0e4xt 41 74 ( ( -LRB- cord-012719-5qa0e4xt 41 75 as as IN cord-012719-5qa0e4xt 41 76 described describe VBN cord-012719-5qa0e4xt 41 77 in in IN cord-012719-5qa0e4xt 41 78 the the DT cord-012719-5qa0e4xt 41 79 following follow VBG cord-012719-5qa0e4xt 41 80 section section NN cord-012719-5qa0e4xt 41 81 ) ) -RRB- cord-012719-5qa0e4xt 41 82 ; ; : cord-012719-5qa0e4xt 41 83 ( ( -LRB- cord-012719-5qa0e4xt 41 84 6 6 LS cord-012719-5qa0e4xt 41 85 ) ) -RRB- cord-012719-5qa0e4xt 41 86 previous previous JJ cord-012719-5qa0e4xt 41 87 ocular ocular JJ cord-012719-5qa0e4xt 41 88 surgery surgery NN cord-012719-5qa0e4xt 41 89 or or CC cord-012719-5qa0e4xt 41 90 ocular ocular JJ cord-012719-5qa0e4xt 41 91 trauma trauma NN cord-012719-5qa0e4xt 41 92 ; ; : cord-012719-5qa0e4xt 41 93 ( ( -LRB- cord-012719-5qa0e4xt 41 94 7 7 LS cord-012719-5qa0e4xt 41 95 ) ) -RRB- cord-012719-5qa0e4xt 41 96 the the DT cord-012719-5qa0e4xt 41 97 presence presence NN cord-012719-5qa0e4xt 41 98 of of IN cord-012719-5qa0e4xt 41 99 neurological neurological JJ cord-012719-5qa0e4xt 41 100 diseases disease NNS cord-012719-5qa0e4xt 41 101 that that WDT cord-012719-5qa0e4xt 41 102 might may MD cord-012719-5qa0e4xt 41 103 affect affect VB cord-012719-5qa0e4xt 41 104 the the DT cord-012719-5qa0e4xt 41 105 RNFL RNFL NNP cord-012719-5qa0e4xt 41 106 thickness thickness NN cord-012719-5qa0e4xt 41 107 , , , cord-012719-5qa0e4xt 41 108 such such JJ cord-012719-5qa0e4xt 41 109 as as IN cord-012719-5qa0e4xt 41 110 Alzheimer Alzheimer NNP cord-012719-5qa0e4xt 41 111 's 's POS cord-012719-5qa0e4xt 41 112 disease disease NN cord-012719-5qa0e4xt 41 113 , , , cord-012719-5qa0e4xt 41 114 vascular vascular JJ cord-012719-5qa0e4xt 41 115 dementia dementia NN cord-012719-5qa0e4xt 41 116 , , , cord-012719-5qa0e4xt 41 117 or or CC cord-012719-5qa0e4xt 41 118 Parkinsonism parkinsonism NN cord-012719-5qa0e4xt 41 119 . . . cord-012719-5qa0e4xt 42 1 All all DT cord-012719-5qa0e4xt 42 2 subjects subject NNS cord-012719-5qa0e4xt 42 3 underwent undergo VBD cord-012719-5qa0e4xt 42 4 complete complete JJ cord-012719-5qa0e4xt 42 5 ophthalmic ophthalmic JJ cord-012719-5qa0e4xt 42 6 examinations examination NNS cord-012719-5qa0e4xt 42 7 , , , cord-012719-5qa0e4xt 42 8 including include VBG cord-012719-5qa0e4xt 42 9 a a DT cord-012719-5qa0e4xt 42 10 best well RBS cord-012719-5qa0e4xt 42 11 - - HYPH cord-012719-5qa0e4xt 42 12 corrected correct VBN cord-012719-5qa0e4xt 42 13 visual visual JJ cord-012719-5qa0e4xt 42 14 acuity acuity NN cord-012719-5qa0e4xt 42 15 measurement measurement NN cord-012719-5qa0e4xt 42 16 , , , cord-012719-5qa0e4xt 42 17 Goldmann Goldmann NNP cord-012719-5qa0e4xt 42 18 applanation applanation NN cord-012719-5qa0e4xt 42 19 tonometry tonometry NNP cord-012719-5qa0e4xt 42 20 , , , cord-012719-5qa0e4xt 42 21 slit slit JJ cord-012719-5qa0e4xt 42 22 - - HYPH cord-012719-5qa0e4xt 42 23 lamp lamp NN cord-012719-5qa0e4xt 42 24 biomicroscopy biomicroscopy NN cord-012719-5qa0e4xt 42 25 , , , cord-012719-5qa0e4xt 42 26 and and CC cord-012719-5qa0e4xt 42 27 gonioscopy gonioscopy NNP cord-012719-5qa0e4xt 42 28 using use VBG cord-012719-5qa0e4xt 42 29 Goldmann Goldmann NNP cord-012719-5qa0e4xt 42 30 three three CD cord-012719-5qa0e4xt 42 31 - - HYPH cord-012719-5qa0e4xt 42 32 mirror mirror NN cord-012719-5qa0e4xt 42 33 lens lens NN cord-012719-5qa0e4xt 42 34 , , , cord-012719-5qa0e4xt 42 35 a a DT cord-012719-5qa0e4xt 42 36 dilated dilated JJ cord-012719-5qa0e4xt 42 37 fundus fundus NN cord-012719-5qa0e4xt 42 38 examination examination NN cord-012719-5qa0e4xt 42 39 , , , cord-012719-5qa0e4xt 42 40 and and CC cord-012719-5qa0e4xt 42 41 RNFL RNFL NNP cord-012719-5qa0e4xt 42 42 and and CC cord-012719-5qa0e4xt 42 43 GCC GCC NNP cord-012719-5qa0e4xt 42 44 thickness thickness NN cord-012719-5qa0e4xt 42 45 measurements measurement NNS cord-012719-5qa0e4xt 42 46 using use VBG cord-012719-5qa0e4xt 42 47 SD SD NNP cord-012719-5qa0e4xt 42 48 - - HYPH cord-012719-5qa0e4xt 42 49 OCT OCT NNP cord-012719-5qa0e4xt 42 50 . . . cord-012719-5qa0e4xt 43 1 The the DT cord-012719-5qa0e4xt 43 2 margins margin NNS cord-012719-5qa0e4xt 43 3 of of IN cord-012719-5qa0e4xt 43 4 the the DT cord-012719-5qa0e4xt 43 5 optic optic JJ cord-012719-5qa0e4xt 43 6 cup cup NN cord-012719-5qa0e4xt 43 7 were be VBD cord-012719-5qa0e4xt 43 8 defined define VBN cord-012719-5qa0e4xt 43 9 as as IN cord-012719-5qa0e4xt 43 10 the the DT cord-012719-5qa0e4xt 43 11 point point NN cord-012719-5qa0e4xt 43 12 of of IN cord-012719-5qa0e4xt 43 13 maximal maximal JJ cord-012719-5qa0e4xt 43 14 inflection inflection NN cord-012719-5qa0e4xt 43 15 of of IN cord-012719-5qa0e4xt 43 16 vessels vessel NNS cord-012719-5qa0e4xt 43 17 crossing cross VBG cord-012719-5qa0e4xt 43 18 the the DT cord-012719-5qa0e4xt 43 19 neuroretinal neuroretinal JJ cord-012719-5qa0e4xt 43 20 rim rim NN cord-012719-5qa0e4xt 43 21 . . . cord-012719-5qa0e4xt 44 1 The the DT cord-012719-5qa0e4xt 44 2 vertical vertical JJ cord-012719-5qa0e4xt 44 3 cup cup NN cord-012719-5qa0e4xt 44 4 diameter diameter NN cord-012719-5qa0e4xt 44 5 was be VBD cord-012719-5qa0e4xt 44 6 measured measure VBN cord-012719-5qa0e4xt 44 7 as as IN cord-012719-5qa0e4xt 44 8 the the DT cord-012719-5qa0e4xt 44 9 vertical vertical JJ cord-012719-5qa0e4xt 44 10 distance distance NN cord-012719-5qa0e4xt 44 11 between between IN cord-012719-5qa0e4xt 44 12 the the DT cord-012719-5qa0e4xt 44 13 points point NNS cord-012719-5qa0e4xt 44 14 of of IN cord-012719-5qa0e4xt 44 15 maximum maximum JJ cord-012719-5qa0e4xt 44 16 centrifugal centrifugal JJ cord-012719-5qa0e4xt 44 17 extension extension NN cord-012719-5qa0e4xt 44 18 of of IN cord-012719-5qa0e4xt 44 19 the the DT cord-012719-5qa0e4xt 44 20 cup cup NN cord-012719-5qa0e4xt 44 21 between between IN cord-012719-5qa0e4xt 44 22 11 11 CD cord-012719-5qa0e4xt 44 23 and and CC cord-012719-5qa0e4xt 44 24 1 1 CD cord-012719-5qa0e4xt 44 25 o'clock o'clock NN cord-012719-5qa0e4xt 44 26 and and CC cord-012719-5qa0e4xt 44 27 5 5 CD cord-012719-5qa0e4xt 44 28 and and CC cord-012719-5qa0e4xt 44 29 7 7 CD cord-012719-5qa0e4xt 44 30 o'clock o'clock NN cord-012719-5qa0e4xt 44 31 . . . cord-012719-5qa0e4xt 45 1 Disc disc NN cord-012719-5qa0e4xt 45 2 hemorrhage hemorrhage NN cord-012719-5qa0e4xt 45 3 , , , cord-012719-5qa0e4xt 45 4 notching notching NN cord-012719-5qa0e4xt 45 5 of of IN cord-012719-5qa0e4xt 45 6 the the DT cord-012719-5qa0e4xt 45 7 neuroretinal neuroretinal JJ cord-012719-5qa0e4xt 45 8 rim rim NNP cord-012719-5qa0e4xt 45 9 , , , cord-012719-5qa0e4xt 45 10 and and CC cord-012719-5qa0e4xt 45 11 thinning thinning NN cord-012719-5qa0e4xt 45 12 of of IN cord-012719-5qa0e4xt 45 13 the the DT cord-012719-5qa0e4xt 45 14 RNFL RNFL NNP cord-012719-5qa0e4xt 45 15 were be VBD cord-012719-5qa0e4xt 45 16 also also RB cord-012719-5qa0e4xt 45 17 documented document VBN cord-012719-5qa0e4xt 45 18 . . . cord-012719-5qa0e4xt 46 1 A a DT cord-012719-5qa0e4xt 46 2 dilated dilated JJ cord-012719-5qa0e4xt 46 3 fundus fundus NN cord-012719-5qa0e4xt 46 4 examination examination NN cord-012719-5qa0e4xt 46 5 was be VBD cord-012719-5qa0e4xt 46 6 performed perform VBN cord-012719-5qa0e4xt 46 7 by by IN cord-012719-5qa0e4xt 46 8 a a DT cord-012719-5qa0e4xt 46 9 single single JJ cord-012719-5qa0e4xt 46 10 glaucoma glaucoma NN cord-012719-5qa0e4xt 46 11 specialist specialist NN cord-012719-5qa0e4xt 46 12 ( ( -LRB- cord-012719-5qa0e4xt 46 13 S.H.L s.h.l NN cord-012719-5qa0e4xt 46 14 ) ) -RRB- cord-012719-5qa0e4xt 46 15 . . . cord-012719-5qa0e4xt 47 1 When when WRB cord-012719-5qa0e4xt 47 2 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 47 3 changes change NNS cord-012719-5qa0e4xt 47 4 were be VBD cord-012719-5qa0e4xt 47 5 suspected suspect VBN cord-012719-5qa0e4xt 47 6 on on IN cord-012719-5qa0e4xt 47 7 fundus fundus NN cord-012719-5qa0e4xt 47 8 examination examination NN cord-012719-5qa0e4xt 47 9 in in IN cord-012719-5qa0e4xt 47 10 control control NN cord-012719-5qa0e4xt 47 11 group group NN cord-012719-5qa0e4xt 47 12 , , , cord-012719-5qa0e4xt 47 13 automated automate VBN cord-012719-5qa0e4xt 47 14 perimetry perimetry NN cord-012719-5qa0e4xt 47 15 was be VBD cord-012719-5qa0e4xt 47 16 performed perform VBN cord-012719-5qa0e4xt 47 17 using use VBG cord-012719-5qa0e4xt 47 18 a a DT cord-012719-5qa0e4xt 47 19 Humphrey Humphrey NNP cord-012719-5qa0e4xt 47 20 Visual Visual NNP cord-012719-5qa0e4xt 47 21 Field Field NNP cord-012719-5qa0e4xt 47 22 Analyzer Analyzer NNP cord-012719-5qa0e4xt 47 23 740i 740i NNP cord-012719-5qa0e4xt 47 24 ( ( -LRB- cord-012719-5qa0e4xt 47 25 Carl Carl NNP cord-012719-5qa0e4xt 47 26 Zeiss Zeiss NNP cord-012719-5qa0e4xt 47 27 Meditec Meditec NNP cord-012719-5qa0e4xt 47 28 Inc Inc NNP cord-012719-5qa0e4xt 47 29 , , , cord-012719-5qa0e4xt 47 30 Dublin Dublin NNP cord-012719-5qa0e4xt 47 31 , , , cord-012719-5qa0e4xt 47 32 CA CA NNP cord-012719-5qa0e4xt 47 33 ) ) -RRB- cord-012719-5qa0e4xt 47 34 and and CC cord-012719-5qa0e4xt 47 35 the the DT cord-012719-5qa0e4xt 47 36 24 24 CD cord-012719-5qa0e4xt 47 37 - - SYM cord-012719-5qa0e4xt 47 38 2 2 CD cord-012719-5qa0e4xt 47 39 Swedish Swedish NNP cord-012719-5qa0e4xt 47 40 Interactive Interactive NNP cord-012719-5qa0e4xt 47 41 Threshold Threshold NNP cord-012719-5qa0e4xt 47 42 Algorithm Algorithm NNP cord-012719-5qa0e4xt 47 43 . . . cord-012719-5qa0e4xt 48 1 Visual visual JJ cord-012719-5qa0e4xt 48 2 field field NN cord-012719-5qa0e4xt 48 3 defects defect NNS cord-012719-5qa0e4xt 48 4 were be VBD cord-012719-5qa0e4xt 48 5 defined define VBN cord-012719-5qa0e4xt 48 6 as as IN cord-012719-5qa0e4xt 48 7 follows follow VBZ cord-012719-5qa0e4xt 48 8 [ [ -LRB- cord-012719-5qa0e4xt 48 9 16 16 CD cord-012719-5qa0e4xt 48 10 ] ] -RRB- cord-012719-5qa0e4xt 49 1 : : : cord-012719-5qa0e4xt 49 2 ( ( -LRB- cord-012719-5qa0e4xt 49 3 1 1 LS cord-012719-5qa0e4xt 49 4 ) ) -RRB- cord-012719-5qa0e4xt 49 5 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 49 6 visual visual JJ cord-012719-5qa0e4xt 49 7 field field NN cord-012719-5qa0e4xt 49 8 defects defect NNS cord-012719-5qa0e4xt 49 9 corresponding correspond VBG cord-012719-5qa0e4xt 49 10 to to IN cord-012719-5qa0e4xt 49 11 ONH ONH NNP cord-012719-5qa0e4xt 49 12 or or CC cord-012719-5qa0e4xt 49 13 RNFL RNFL NNP cord-012719-5qa0e4xt 49 14 changes change NNS cord-012719-5qa0e4xt 49 15 ; ; , cord-012719-5qa0e4xt 49 16 ( ( -LRB- cord-012719-5qa0e4xt 49 17 2 2 LS cord-012719-5qa0e4xt 49 18 ) ) -RRB- cord-012719-5qa0e4xt 49 19 glaucoma glaucoma NN cord-012719-5qa0e4xt 49 20 hemifield hemifield NNP cord-012719-5qa0e4xt 49 21 test test NN cord-012719-5qa0e4xt 49 22 results result NNS cord-012719-5qa0e4xt 49 23 outside outside RB cord-012719-5qa0e4xt 49 24 of of IN cord-012719-5qa0e4xt 49 25 the the DT cord-012719-5qa0e4xt 49 26 normal normal JJ cord-012719-5qa0e4xt 49 27 limits limit NNS cord-012719-5qa0e4xt 49 28 ; ; : cord-012719-5qa0e4xt 49 29 and and CC cord-012719-5qa0e4xt 49 30 ( ( -LRB- cord-012719-5qa0e4xt 49 31 3 3 LS cord-012719-5qa0e4xt 49 32 ) ) -RRB- cord-012719-5qa0e4xt 49 33 a a DT cord-012719-5qa0e4xt 49 34 cluster cluster NN cord-012719-5qa0e4xt 49 35 of of IN cord-012719-5qa0e4xt 49 36 three three CD cord-012719-5qa0e4xt 49 37 or or CC cord-012719-5qa0e4xt 49 38 more more JJR cord-012719-5qa0e4xt 49 39 nonedge nonedge JJ cord-012719-5qa0e4xt 49 40 , , , cord-012719-5qa0e4xt 49 41 contiguous contiguous JJ cord-012719-5qa0e4xt 49 42 points point NNS cord-012719-5qa0e4xt 49 43 , , , cord-012719-5qa0e4xt 49 44 not not RB cord-012719-5qa0e4xt 49 45 crossing cross VBG cord-012719-5qa0e4xt 49 46 the the DT cord-012719-5qa0e4xt 49 47 horizontal horizontal JJ cord-012719-5qa0e4xt 49 48 meridian meridian NN cord-012719-5qa0e4xt 49 49 , , , cord-012719-5qa0e4xt 49 50 with with IN cord-012719-5qa0e4xt 49 51 P p NN cord-012719-5qa0e4xt 49 52 values value NNS cord-012719-5qa0e4xt 49 53 < < XX cord-012719-5qa0e4xt 49 54 0.05 0.05 CD cord-012719-5qa0e4xt 49 55 as as IN cord-012719-5qa0e4xt 49 56 compared compare VBN cord-012719-5qa0e4xt 49 57 with with IN cord-012719-5qa0e4xt 49 58 the the DT cord-012719-5qa0e4xt 49 59 age age NN cord-012719-5qa0e4xt 49 60 - - HYPH cord-012719-5qa0e4xt 49 61 matched match VBN cord-012719-5qa0e4xt 49 62 normal normal JJ cord-012719-5qa0e4xt 49 63 on on IN cord-012719-5qa0e4xt 49 64 the the DT cord-012719-5qa0e4xt 49 65 pattern pattern NN cord-012719-5qa0e4xt 49 66 deviation deviation NN cord-012719-5qa0e4xt 49 67 plot plot NN cord-012719-5qa0e4xt 49 68 , , , cord-012719-5qa0e4xt 49 69 one one CD cord-012719-5qa0e4xt 49 70 of of IN cord-012719-5qa0e4xt 49 71 which which WDT cord-012719-5qa0e4xt 49 72 must must MD cord-012719-5qa0e4xt 49 73 have have VB cord-012719-5qa0e4xt 49 74 a a DT cord-012719-5qa0e4xt 49 75 P p NN cord-012719-5qa0e4xt 49 76 value value NN cord-012719-5qa0e4xt 49 77 < < XX cord-012719-5qa0e4xt 49 78 0.01 0.01 CD cord-012719-5qa0e4xt 49 79 . . . cord-012719-5qa0e4xt 50 1 The the DT cord-012719-5qa0e4xt 50 2 RNFL RNFL NNP cord-012719-5qa0e4xt 50 3 and and CC cord-012719-5qa0e4xt 50 4 GCC GCC NNP cord-012719-5qa0e4xt 50 5 thicknesses thickness NNS cord-012719-5qa0e4xt 50 6 were be VBD cord-012719-5qa0e4xt 50 7 measured measure VBN cord-012719-5qa0e4xt 50 8 using use VBG cord-012719-5qa0e4xt 50 9 a a DT cord-012719-5qa0e4xt 50 10 SD SD NNP cord-012719-5qa0e4xt 50 11 - - HYPH cord-012719-5qa0e4xt 50 12 OCT OCT NNP cord-012719-5qa0e4xt 50 13 device device NN cord-012719-5qa0e4xt 50 14 ( ( -LRB- cord-012719-5qa0e4xt 50 15 RT RT NNP cord-012719-5qa0e4xt 50 16 - - HYPH cord-012719-5qa0e4xt 50 17 Vue Vue NNP cord-012719-5qa0e4xt 50 18 100 100 CD cord-012719-5qa0e4xt 50 19 , , , cord-012719-5qa0e4xt 50 20 RT RT NNP cord-012719-5qa0e4xt 50 21 Vue Vue NNP cord-012719-5qa0e4xt 50 22 , , , cord-012719-5qa0e4xt 50 23 Fremont Fremont NNP cord-012719-5qa0e4xt 50 24 , , , cord-012719-5qa0e4xt 50 25 CA CA NNP cord-012719-5qa0e4xt 50 26 ) ) -RRB- cord-012719-5qa0e4xt 50 27 after after IN cord-012719-5qa0e4xt 50 28 pupillary pupillary JJ cord-012719-5qa0e4xt 50 29 dilation dilation NN cord-012719-5qa0e4xt 50 30 . . . cord-012719-5qa0e4xt 51 1 An an DT cord-012719-5qa0e4xt 51 2 internal internal JJ cord-012719-5qa0e4xt 51 3 nasal nasal NN cord-012719-5qa0e4xt 51 4 fixation fixation NN cord-012719-5qa0e4xt 51 5 light light NN cord-012719-5qa0e4xt 51 6 was be VBD cord-012719-5qa0e4xt 51 7 used use VBN cord-012719-5qa0e4xt 51 8 to to TO cord-012719-5qa0e4xt 51 9 center center VB cord-012719-5qa0e4xt 51 10 the the DT cord-012719-5qa0e4xt 51 11 ONH ONH NNP cord-012719-5qa0e4xt 51 12 in in IN cord-012719-5qa0e4xt 51 13 the the DT cord-012719-5qa0e4xt 51 14 rectangle rectangle NN cord-012719-5qa0e4xt 51 15 image image NN cord-012719-5qa0e4xt 51 16 mode mode NN cord-012719-5qa0e4xt 51 17 , , , cord-012719-5qa0e4xt 51 18 and and CC cord-012719-5qa0e4xt 51 19 cpRNFL cprnfl NN cord-012719-5qa0e4xt 51 20 thickness thickness NN cord-012719-5qa0e4xt 51 21 was be VBD cord-012719-5qa0e4xt 51 22 measured measure VBN cord-012719-5qa0e4xt 51 23 . . . cord-012719-5qa0e4xt 52 1 To to TO cord-012719-5qa0e4xt 52 2 improve improve VB cord-012719-5qa0e4xt 52 3 the the DT cord-012719-5qa0e4xt 52 4 scan scan JJ cord-012719-5qa0e4xt 52 5 quality quality NN cord-012719-5qa0e4xt 52 6 , , , cord-012719-5qa0e4xt 52 7 scans scan NNS cord-012719-5qa0e4xt 52 8 with with IN cord-012719-5qa0e4xt 52 9 signal signal NN cord-012719-5qa0e4xt 52 10 strength strength NN cord-012719-5qa0e4xt 52 11 intensity intensity NN cord-012719-5qa0e4xt 53 1 < < XX cord-012719-5qa0e4xt 53 2 40 40 CD cord-012719-5qa0e4xt 53 3 were be VBD cord-012719-5qa0e4xt 53 4 excluded exclude VBN cord-012719-5qa0e4xt 53 5 from from IN cord-012719-5qa0e4xt 53 6 the the DT cord-012719-5qa0e4xt 53 7 analyses analysis NNS cord-012719-5qa0e4xt 53 8 . . . cord-012719-5qa0e4xt 54 1 Average average JJ cord-012719-5qa0e4xt 54 2 RNFL RNFL NNP cord-012719-5qa0e4xt 54 3 thickness thickness NN cord-012719-5qa0e4xt 54 4 and and CC cord-012719-5qa0e4xt 54 5 RNFL RNFL NNP cord-012719-5qa0e4xt 54 6 thickness thickness NN cord-012719-5qa0e4xt 54 7 in in IN cord-012719-5qa0e4xt 54 8 eight eight CD cord-012719-5qa0e4xt 54 9 peripapillary peripapillary JJ cord-012719-5qa0e4xt 54 10 sectors sector NNS cord-012719-5qa0e4xt 54 11 ( ( -LRB- cord-012719-5qa0e4xt 54 12 superior superior JJ cord-012719-5qa0e4xt 54 13 nasal nasal NN cord-012719-5qa0e4xt 54 14 , , , cord-012719-5qa0e4xt 54 15 superior superior JJ cord-012719-5qa0e4xt 54 16 temporal temporal JJ cord-012719-5qa0e4xt 54 17 , , , cord-012719-5qa0e4xt 54 18 temporal temporal JJ cord-012719-5qa0e4xt 54 19 upper upper JJ cord-012719-5qa0e4xt 54 20 , , , cord-012719-5qa0e4xt 54 21 temporal temporal JJ cord-012719-5qa0e4xt 54 22 lower lower RBR cord-012719-5qa0e4xt 54 23 , , , cord-012719-5qa0e4xt 54 24 inferior inferior JJ cord-012719-5qa0e4xt 54 25 temporal temporal JJ cord-012719-5qa0e4xt 54 26 , , , cord-012719-5qa0e4xt 54 27 inferior inferior JJ cord-012719-5qa0e4xt 54 28 nasal nasal NN cord-012719-5qa0e4xt 54 29 , , , cord-012719-5qa0e4xt 54 30 nasal nasal JJ cord-012719-5qa0e4xt 54 31 upper upper JJ cord-012719-5qa0e4xt 54 32 , , , cord-012719-5qa0e4xt 54 33 and and CC cord-012719-5qa0e4xt 54 34 nasal nasal JJ cord-012719-5qa0e4xt 54 35 lower low JJR cord-012719-5qa0e4xt 54 36 sector sector NN cord-012719-5qa0e4xt 54 37 ) ) -RRB- cord-012719-5qa0e4xt 54 38 were be VBD cord-012719-5qa0e4xt 54 39 calculated calculate VBN cord-012719-5qa0e4xt 54 40 automatically automatically RB cord-012719-5qa0e4xt 54 41 . . . cord-012719-5qa0e4xt 55 1 Thereafter thereafter RB cord-012719-5qa0e4xt 55 2 , , , cord-012719-5qa0e4xt 55 3 we -PRON- PRP cord-012719-5qa0e4xt 55 4 grouped group VBD cord-012719-5qa0e4xt 55 5 eight eight CD cord-012719-5qa0e4xt 55 6 peripapillary peripapillary JJ cord-012719-5qa0e4xt 55 7 sectors sector NNS cord-012719-5qa0e4xt 55 8 into into IN cord-012719-5qa0e4xt 55 9 four four CD cord-012719-5qa0e4xt 55 10 sectors sector NNS cord-012719-5qa0e4xt 55 11 . . . cord-012719-5qa0e4xt 56 1 Superior Superior NNP cord-012719-5qa0e4xt 56 2 RNFL RNFL NNP cord-012719-5qa0e4xt 56 3 thickness thickness NN cord-012719-5qa0e4xt 56 4 indicates indicate VBZ cord-012719-5qa0e4xt 56 5 the the DT cord-012719-5qa0e4xt 56 6 average average NN cord-012719-5qa0e4xt 56 7 of of IN cord-012719-5qa0e4xt 56 8 the the DT cord-012719-5qa0e4xt 56 9 superior superior JJ cord-012719-5qa0e4xt 56 10 nasal nasal NN cord-012719-5qa0e4xt 56 11 and and CC cord-012719-5qa0e4xt 56 12 superior superior JJ cord-012719-5qa0e4xt 56 13 temporal temporal JJ cord-012719-5qa0e4xt 56 14 sectors sector NNS cord-012719-5qa0e4xt 56 15 . . . cord-012719-5qa0e4xt 57 1 Temporal temporal JJ cord-012719-5qa0e4xt 57 2 RNFL RNFL NNP cord-012719-5qa0e4xt 57 3 thickness thickness NN cord-012719-5qa0e4xt 57 4 indicates indicate VBZ cord-012719-5qa0e4xt 57 5 the the DT cord-012719-5qa0e4xt 57 6 average average NN cord-012719-5qa0e4xt 57 7 of of IN cord-012719-5qa0e4xt 57 8 the the DT cord-012719-5qa0e4xt 57 9 temporal temporal JJ cord-012719-5qa0e4xt 57 10 upper upper JJ cord-012719-5qa0e4xt 57 11 and and CC cord-012719-5qa0e4xt 57 12 temporal temporal JJ cord-012719-5qa0e4xt 57 13 lower low JJR cord-012719-5qa0e4xt 57 14 sectors sector NNS cord-012719-5qa0e4xt 57 15 . . . cord-012719-5qa0e4xt 58 1 Inferior inferior JJ cord-012719-5qa0e4xt 58 2 RNFL RNFL NNP cord-012719-5qa0e4xt 58 3 thickness thickness NN cord-012719-5qa0e4xt 58 4 indicates indicate VBZ cord-012719-5qa0e4xt 58 5 the the DT cord-012719-5qa0e4xt 58 6 average average NN cord-012719-5qa0e4xt 58 7 of of IN cord-012719-5qa0e4xt 58 8 the the DT cord-012719-5qa0e4xt 58 9 inferior inferior JJ cord-012719-5qa0e4xt 58 10 temporal temporal JJ cord-012719-5qa0e4xt 58 11 and and CC cord-012719-5qa0e4xt 58 12 inferior inferior JJ cord-012719-5qa0e4xt 58 13 nasal nasal NN cord-012719-5qa0e4xt 58 14 sectors sector NNS cord-012719-5qa0e4xt 58 15 . . . cord-012719-5qa0e4xt 59 1 Nasal nasal NN cord-012719-5qa0e4xt 59 2 RNFL RNFL NNP cord-012719-5qa0e4xt 59 3 thickness thickness NN cord-012719-5qa0e4xt 59 4 indicates indicate VBZ cord-012719-5qa0e4xt 59 5 the the DT cord-012719-5qa0e4xt 59 6 average average NN cord-012719-5qa0e4xt 59 7 of of IN cord-012719-5qa0e4xt 59 8 the the DT cord-012719-5qa0e4xt 59 9 nasal nasal NN cord-012719-5qa0e4xt 59 10 upper upper JJ cord-012719-5qa0e4xt 59 11 and and CC cord-012719-5qa0e4xt 59 12 nasal nasal JJ cord-012719-5qa0e4xt 59 13 lower low JJR cord-012719-5qa0e4xt 59 14 sectors sector NNS cord-012719-5qa0e4xt 59 15 . . . cord-012719-5qa0e4xt 60 1 GCC gcc NN cord-012719-5qa0e4xt 60 2 thickness thickness NN cord-012719-5qa0e4xt 60 3 was be VBD cord-012719-5qa0e4xt 60 4 also also RB cord-012719-5qa0e4xt 60 5 measured measure VBN cord-012719-5qa0e4xt 60 6 in in IN cord-012719-5qa0e4xt 60 7 two two CD cord-012719-5qa0e4xt 60 8 areas area NNS cord-012719-5qa0e4xt 60 9 ( ( -LRB- cord-012719-5qa0e4xt 60 10 superior superior JJ cord-012719-5qa0e4xt 60 11 and and CC cord-012719-5qa0e4xt 60 12 inferior inferior JJ cord-012719-5qa0e4xt 60 13 sector sector NN cord-012719-5qa0e4xt 60 14 ) ) -RRB- cord-012719-5qa0e4xt 60 15 . . . cord-012719-5qa0e4xt 61 1 All all DT cord-012719-5qa0e4xt 61 2 OCT OCT NNP cord-012719-5qa0e4xt 61 3 images image NNS cord-012719-5qa0e4xt 61 4 were be VBD cord-012719-5qa0e4xt 61 5 evaluated evaluate VBN cord-012719-5qa0e4xt 61 6 by by IN cord-012719-5qa0e4xt 61 7 the the DT cord-012719-5qa0e4xt 61 8 same same JJ cord-012719-5qa0e4xt 61 9 observer observer NN cord-012719-5qa0e4xt 61 10 ( ( -LRB- cord-012719-5qa0e4xt 61 11 S.H.L s.h.l NN cord-012719-5qa0e4xt 61 12 ) ) -RRB- cord-012719-5qa0e4xt 61 13 . . . cord-012719-5qa0e4xt 62 1 Statistical statistical JJ cord-012719-5qa0e4xt 62 2 analyses analysis NNS cord-012719-5qa0e4xt 62 3 were be VBD cord-012719-5qa0e4xt 62 4 performed perform VBN cord-012719-5qa0e4xt 62 5 using use VBG cord-012719-5qa0e4xt 62 6 SPSS SPSS NNP cord-012719-5qa0e4xt 62 7 for for IN cord-012719-5qa0e4xt 62 8 Windows Windows NNP cord-012719-5qa0e4xt 62 9 software software NN cord-012719-5qa0e4xt 62 10 version version NN cord-012719-5qa0e4xt 62 11 18.0 18.0 CD cord-012719-5qa0e4xt 63 1 ( ( -LRB- cord-012719-5qa0e4xt 63 2 SPSS SPSS NNP cord-012719-5qa0e4xt 63 3 Inc Inc NNP cord-012719-5qa0e4xt 63 4 , , , cord-012719-5qa0e4xt 63 5 Chicago Chicago NNP cord-012719-5qa0e4xt 63 6 , , , cord-012719-5qa0e4xt 63 7 IL IL NNP cord-012719-5qa0e4xt 63 8 ) ) -RRB- cord-012719-5qa0e4xt 63 9 . . . cord-012719-5qa0e4xt 64 1 Independent independent JJ cord-012719-5qa0e4xt 64 2 t t NN cord-012719-5qa0e4xt 64 3 - - HYPH cord-012719-5qa0e4xt 64 4 tests test NNS cord-012719-5qa0e4xt 64 5 and and CC cord-012719-5qa0e4xt 64 6 chi chi JJ cord-012719-5qa0e4xt 64 7 - - JJ cord-012719-5qa0e4xt 64 8 square square JJ cord-012719-5qa0e4xt 64 9 tests test NNS cord-012719-5qa0e4xt 64 10 were be VBD cord-012719-5qa0e4xt 64 11 used use VBN cord-012719-5qa0e4xt 64 12 to to TO cord-012719-5qa0e4xt 64 13 compare compare VB cord-012719-5qa0e4xt 64 14 baseline baseline JJ cord-012719-5qa0e4xt 64 15 characteristics characteristic NNS cord-012719-5qa0e4xt 64 16 of of IN cord-012719-5qa0e4xt 64 17 unilateral unilateral JJ cord-012719-5qa0e4xt 64 18 XFS xfs NN cord-012719-5qa0e4xt 64 19 patients patient NNS cord-012719-5qa0e4xt 64 20 and and CC cord-012719-5qa0e4xt 64 21 controls control NNS cord-012719-5qa0e4xt 64 22 . . . cord-012719-5qa0e4xt 65 1 One one CD cord-012719-5qa0e4xt 65 2 - - HYPH cord-012719-5qa0e4xt 65 3 way way NN cord-012719-5qa0e4xt 65 4 analysis analysis NN cord-012719-5qa0e4xt 65 5 of of IN cord-012719-5qa0e4xt 65 6 variance variance NN cord-012719-5qa0e4xt 65 7 ( ( -LRB- cord-012719-5qa0e4xt 65 8 ANOVA ANOVA NNP cord-012719-5qa0e4xt 65 9 ) ) -RRB- cord-012719-5qa0e4xt 65 10 was be VBD cord-012719-5qa0e4xt 65 11 used use VBN cord-012719-5qa0e4xt 65 12 to to TO cord-012719-5qa0e4xt 65 13 compare compare VB cord-012719-5qa0e4xt 65 14 RNFL RNFL NNP cord-012719-5qa0e4xt 65 15 and and CC cord-012719-5qa0e4xt 65 16 GCC GCC NNP cord-012719-5qa0e4xt 65 17 thickness thickness NN cord-012719-5qa0e4xt 65 18 among among IN cord-012719-5qa0e4xt 65 19 three three CD cord-012719-5qa0e4xt 65 20 groups group NNS cord-012719-5qa0e4xt 65 21 ( ( -LRB- cord-012719-5qa0e4xt 65 22 XFS xfs VB cord-012719-5qa0e4xt 65 23 - - HYPH cord-012719-5qa0e4xt 65 24 affected affected JJ cord-012719-5qa0e4xt 65 25 eye eye NN cord-012719-5qa0e4xt 65 26 , , , cord-012719-5qa0e4xt 65 27 fellow fellow JJ cord-012719-5qa0e4xt 65 28 eye eye NN cord-012719-5qa0e4xt 65 29 , , , cord-012719-5qa0e4xt 65 30 and and CC cord-012719-5qa0e4xt 65 31 control control NN cord-012719-5qa0e4xt 65 32 group group NN cord-012719-5qa0e4xt 65 33 ) ) -RRB- cord-012719-5qa0e4xt 65 34 . . . cord-012719-5qa0e4xt 66 1 In in IN cord-012719-5qa0e4xt 66 2 posthoc posthoc NNP cord-012719-5qa0e4xt 66 3 analysis analysis NN cord-012719-5qa0e4xt 66 4 , , , cord-012719-5qa0e4xt 66 5 Tukey Tukey NNP cord-012719-5qa0e4xt 66 6 's 's POS cord-012719-5qa0e4xt 66 7 test test NN cord-012719-5qa0e4xt 66 8 was be VBD cord-012719-5qa0e4xt 66 9 used use VBN cord-012719-5qa0e4xt 66 10 to to TO cord-012719-5qa0e4xt 66 11 compare compare VB cord-012719-5qa0e4xt 66 12 two two CD cord-012719-5qa0e4xt 66 13 groups group NNS cord-012719-5qa0e4xt 66 14 . . . cord-012719-5qa0e4xt 67 1 After after IN cord-012719-5qa0e4xt 67 2 Bonferroni Bonferroni NNP cord-012719-5qa0e4xt 67 3 's 's POS cord-012719-5qa0e4xt 67 4 correction correction NN cord-012719-5qa0e4xt 67 5 of of IN cord-012719-5qa0e4xt 67 6 multigroup multigroup NNP cord-012719-5qa0e4xt 67 7 comparisons comparison NNS cord-012719-5qa0e4xt 67 8 , , , cord-012719-5qa0e4xt 67 9 a a DT cord-012719-5qa0e4xt 67 10 P p NN cord-012719-5qa0e4xt 67 11 value value NN cord-012719-5qa0e4xt 67 12 of of IN cord-012719-5qa0e4xt 67 13 0.0167 0.0167 CD cord-012719-5qa0e4xt 67 14 was be VBD cord-012719-5qa0e4xt 67 15 considered consider VBN cord-012719-5qa0e4xt 67 16 statistically statistically RB cord-012719-5qa0e4xt 67 17 significant significant JJ cord-012719-5qa0e4xt 67 18 , , , cord-012719-5qa0e4xt 67 19 at at IN cord-012719-5qa0e4xt 67 20 a a DT cord-012719-5qa0e4xt 67 21 significance significance NN cord-012719-5qa0e4xt 67 22 level level NN cord-012719-5qa0e4xt 67 23 of of IN cord-012719-5qa0e4xt 67 24 0.05 0.05 CD cord-012719-5qa0e4xt 67 25 . . . cord-012719-5qa0e4xt 68 1 Table table NN cord-012719-5qa0e4xt 68 2 1 1 CD cord-012719-5qa0e4xt 68 3 compares compare VBZ cord-012719-5qa0e4xt 68 4 the the DT cord-012719-5qa0e4xt 68 5 baseline baseline JJ cord-012719-5qa0e4xt 68 6 characteristics characteristic NNS cord-012719-5qa0e4xt 68 7 of of IN cord-012719-5qa0e4xt 68 8 the the DT cord-012719-5qa0e4xt 68 9 XFS xfs NN cord-012719-5qa0e4xt 68 10 and and CC cord-012719-5qa0e4xt 68 11 control control NN cord-012719-5qa0e4xt 68 12 groups group NNS cord-012719-5qa0e4xt 68 13 . . . cord-012719-5qa0e4xt 69 1 The the DT cord-012719-5qa0e4xt 69 2 mean mean JJ cord-012719-5qa0e4xt 69 3 age age NN cord-012719-5qa0e4xt 69 4 was be VBD cord-012719-5qa0e4xt 69 5 73.3 73.3 CD cord-012719-5qa0e4xt 69 6 ± ± CD cord-012719-5qa0e4xt 69 7 6.3 6.3 CD cord-012719-5qa0e4xt 69 8 for for IN cord-012719-5qa0e4xt 69 9 XFS xfs JJ cord-012719-5qa0e4xt 69 10 patients patient NNS cord-012719-5qa0e4xt 69 11 and and CC cord-012719-5qa0e4xt 69 12 74.3 74.3 CD cord-012719-5qa0e4xt 69 13 ± ± CD cord-012719-5qa0e4xt 69 14 7.2 7.2 CD cord-012719-5qa0e4xt 69 15 for for IN cord-012719-5qa0e4xt 69 16 healthy healthy JJ cord-012719-5qa0e4xt 69 17 controls control NNS cord-012719-5qa0e4xt 69 18 ( ( -LRB- cord-012719-5qa0e4xt 69 19 P p NN cord-012719-5qa0e4xt 69 20 = = SYM cord-012719-5qa0e4xt 69 21 0.536 0.536 CD cord-012719-5qa0e4xt 69 22 ) ) -RRB- cord-012719-5qa0e4xt 69 23 . . . cord-012719-5qa0e4xt 70 1 There there EX cord-012719-5qa0e4xt 70 2 was be VBD cord-012719-5qa0e4xt 70 3 no no DT cord-012719-5qa0e4xt 70 4 difference difference NN cord-012719-5qa0e4xt 70 5 in in IN cord-012719-5qa0e4xt 70 6 the the DT cord-012719-5qa0e4xt 70 7 numbers number NNS cord-012719-5qa0e4xt 70 8 of of IN cord-012719-5qa0e4xt 70 9 males male NNS cord-012719-5qa0e4xt 70 10 and and CC cord-012719-5qa0e4xt 70 11 females female NNS cord-012719-5qa0e4xt 70 12 comprising comprise VBG cord-012719-5qa0e4xt 70 13 either either CC cord-012719-5qa0e4xt 70 14 group group NN cord-012719-5qa0e4xt 70 15 ( ( -LRB- cord-012719-5qa0e4xt 70 16 P p NN cord-012719-5qa0e4xt 70 17 = = SYM cord-012719-5qa0e4xt 70 18 0.551 0.551 CD cord-012719-5qa0e4xt 70 19 ) ) -RRB- cord-012719-5qa0e4xt 70 20 . . . cord-012719-5qa0e4xt 71 1 The the DT cord-012719-5qa0e4xt 71 2 mean mean JJ cord-012719-5qa0e4xt 71 3 IOP IOP NNP cord-012719-5qa0e4xt 71 4 of of IN cord-012719-5qa0e4xt 71 5 XFS xfs NN cord-012719-5qa0e4xt 71 6 - - HYPH cord-012719-5qa0e4xt 71 7 affected affect VBN cord-012719-5qa0e4xt 71 8 eyes eye NNS cord-012719-5qa0e4xt 71 9 ( ( -LRB- cord-012719-5qa0e4xt 71 10 17.2 17.2 CD cord-012719-5qa0e4xt 71 11 ± ± CD cord-012719-5qa0e4xt 71 12 2.8 2.8 CD cord-012719-5qa0e4xt 71 13 mmHg mmHg NNS cord-012719-5qa0e4xt 71 14 ) ) -RRB- cord-012719-5qa0e4xt 71 15 was be VBD cord-012719-5qa0e4xt 71 16 higher high JJR cord-012719-5qa0e4xt 71 17 than than IN cord-012719-5qa0e4xt 71 18 that that DT cord-012719-5qa0e4xt 71 19 of of IN cord-012719-5qa0e4xt 71 20 fellow fellow JJ cord-012719-5qa0e4xt 71 21 eyes eye NNS cord-012719-5qa0e4xt 71 22 ( ( -LRB- cord-012719-5qa0e4xt 71 23 16.8 16.8 CD cord-012719-5qa0e4xt 71 24 ± ± CD cord-012719-5qa0e4xt 71 25 2.2 2.2 CD cord-012719-5qa0e4xt 71 26 mmHg mmHg NNS cord-012719-5qa0e4xt 71 27 ) ) -RRB- cord-012719-5qa0e4xt 71 28 and and CC cord-012719-5qa0e4xt 71 29 healthy healthy JJ cord-012719-5qa0e4xt 71 30 controls control NNS cord-012719-5qa0e4xt 71 31 ( ( -LRB- cord-012719-5qa0e4xt 71 32 14.5 14.5 CD cord-012719-5qa0e4xt 71 33 ± ± NNP cord-012719-5qa0e4xt 71 34 2.3 2.3 CD cord-012719-5qa0e4xt 71 35 mmHg mmHg NNS cord-012719-5qa0e4xt 71 36 ) ) -RRB- cord-012719-5qa0e4xt 72 1 ( ( -LRB- cord-012719-5qa0e4xt 72 2 P p NN cord-012719-5qa0e4xt 72 3 = = SYM cord-012719-5qa0e4xt 72 4 0.004 0.004 CD cord-012719-5qa0e4xt 72 5 ) ) -RRB- cord-012719-5qa0e4xt 72 6 . . . cord-012719-5qa0e4xt 73 1 A a DT cord-012719-5qa0e4xt 73 2 total total NN cord-012719-5qa0e4xt 73 3 of of IN cord-012719-5qa0e4xt 73 4 28 28 CD cord-012719-5qa0e4xt 73 5 pseudophakic pseudophakic NN cord-012719-5qa0e4xt 73 6 eyes eye NNS cord-012719-5qa0e4xt 73 7 ( ( -LRB- cord-012719-5qa0e4xt 73 8 8 8 CD cord-012719-5qa0e4xt 73 9 XFS xfs NN cord-012719-5qa0e4xt 73 10 - - HYPH cord-012719-5qa0e4xt 73 11 affected affect VBN cord-012719-5qa0e4xt 73 12 eyes eye NNS cord-012719-5qa0e4xt 73 13 , , , cord-012719-5qa0e4xt 73 14 11 11 CD cord-012719-5qa0e4xt 73 15 fellow fellow JJ cord-012719-5qa0e4xt 73 16 eyes eye NNS cord-012719-5qa0e4xt 73 17 and and CC cord-012719-5qa0e4xt 73 18 9 9 CD cord-012719-5qa0e4xt 73 19 controls control NNS cord-012719-5qa0e4xt 73 20 ) ) -RRB- cord-012719-5qa0e4xt 73 21 were be VBD cord-012719-5qa0e4xt 73 22 included include VBN cord-012719-5qa0e4xt 73 23 , , , cord-012719-5qa0e4xt 73 24 but but CC cord-012719-5qa0e4xt 73 25 , , , cord-012719-5qa0e4xt 73 26 there there EX cord-012719-5qa0e4xt 73 27 was be VBD cord-012719-5qa0e4xt 73 28 no no DT cord-012719-5qa0e4xt 73 29 significant significant JJ cord-012719-5qa0e4xt 73 30 difference difference NN cord-012719-5qa0e4xt 73 31 between between IN cord-012719-5qa0e4xt 73 32 groups group NNS cord-012719-5qa0e4xt 73 33 in in IN cord-012719-5qa0e4xt 73 34 terms term NNS cord-012719-5qa0e4xt 73 35 of of IN cord-012719-5qa0e4xt 73 36 lens lens NN cord-012719-5qa0e4xt 73 37 status status NN cord-012719-5qa0e4xt 73 38 ( ( -LRB- cord-012719-5qa0e4xt 73 39 P p NN cord-012719-5qa0e4xt 73 40 = = SYM cord-012719-5qa0e4xt 73 41 0.772 0.772 CD cord-012719-5qa0e4xt 73 42 ) ) -RRB- cord-012719-5qa0e4xt 73 43 or or CC cord-012719-5qa0e4xt 73 44 cup cup NN cord-012719-5qa0e4xt 73 45 to to TO cord-012719-5qa0e4xt 73 46 disc disc NN cord-012719-5qa0e4xt 73 47 ratio ratio NN cord-012719-5qa0e4xt 74 1 ( ( -LRB- cord-012719-5qa0e4xt 74 2 P p NN cord-012719-5qa0e4xt 74 3 = = SYM cord-012719-5qa0e4xt 74 4 0.759 0.759 CD cord-012719-5qa0e4xt 74 5 ) ) -RRB- cord-012719-5qa0e4xt 74 6 , , . cord-012719-5qa0e4xt 75 1 and and CC cord-012719-5qa0e4xt 75 2 there there EX cord-012719-5qa0e4xt 75 3 were be VBD cord-012719-5qa0e4xt 75 4 no no DT cord-012719-5qa0e4xt 75 5 patients patient NNS cord-012719-5qa0e4xt 75 6 with with IN cord-012719-5qa0e4xt 75 7 abnormal abnormal JJ cord-012719-5qa0e4xt 75 8 myopic myopic JJ cord-012719-5qa0e4xt 75 9 optic optic JJ cord-012719-5qa0e4xt 75 10 disc disc NN cord-012719-5qa0e4xt 75 11 features feature NNS cord-012719-5qa0e4xt 75 12 such such JJ cord-012719-5qa0e4xt 75 13 as as IN cord-012719-5qa0e4xt 75 14 severe severe JJ cord-012719-5qa0e4xt 75 15 disc disc NN cord-012719-5qa0e4xt 75 16 tilt tilt NN cord-012719-5qa0e4xt 75 17 and and CC cord-012719-5qa0e4xt 75 18 peripapillary peripapillary JJ cord-012719-5qa0e4xt 75 19 atrophy atrophy NN cord-012719-5qa0e4xt 75 20 in in IN cord-012719-5qa0e4xt 75 21 any any DT cord-012719-5qa0e4xt 75 22 groups group NNS cord-012719-5qa0e4xt 75 23 . . . cord-012719-5qa0e4xt 76 1 RNFL rnfl NN cord-012719-5qa0e4xt 76 2 parameters parameter NNS cord-012719-5qa0e4xt 76 3 are be VBP cord-012719-5qa0e4xt 76 4 summarized summarize VBN cord-012719-5qa0e4xt 76 5 in in IN cord-012719-5qa0e4xt 76 6 Table Table NNP cord-012719-5qa0e4xt 76 7 2 2 CD cord-012719-5qa0e4xt 76 8 . . . cord-012719-5qa0e4xt 77 1 Although although IN cord-012719-5qa0e4xt 77 2 there there EX cord-012719-5qa0e4xt 77 3 was be VBD cord-012719-5qa0e4xt 77 4 borderline borderline JJ cord-012719-5qa0e4xt 77 5 statistical statistical JJ cord-012719-5qa0e4xt 77 6 significance significance NN cord-012719-5qa0e4xt 77 7 ( ( -LRB- cord-012719-5qa0e4xt 77 8 P p NN cord-012719-5qa0e4xt 77 9 = = SYM cord-012719-5qa0e4xt 77 10 0.057 0.057 CD cord-012719-5qa0e4xt 77 11 by by IN cord-012719-5qa0e4xt 77 12 one one CD cord-012719-5qa0e4xt 77 13 - - HYPH cord-012719-5qa0e4xt 77 14 way way NN cord-012719-5qa0e4xt 77 15 ANOVA ANOVA NNP cord-012719-5qa0e4xt 77 16 ) ) -RRB- cord-012719-5qa0e4xt 77 17 , , , cord-012719-5qa0e4xt 77 18 post post VB cord-012719-5qa0e4xt 77 19 - - JJ cord-012719-5qa0e4xt 77 20 hoc hoc JJ cord-012719-5qa0e4xt 77 21 analysis analysis NN cord-012719-5qa0e4xt 77 22 revealed reveal VBD cord-012719-5qa0e4xt 77 23 average average JJ cord-012719-5qa0e4xt 77 24 RNFL RNFL NNP cord-012719-5qa0e4xt 77 25 thickness thickness NN cord-012719-5qa0e4xt 77 26 of of IN cord-012719-5qa0e4xt 77 27 XFS xfs NN cord-012719-5qa0e4xt 77 28 - - HYPH cord-012719-5qa0e4xt 77 29 affected affect VBN cord-012719-5qa0e4xt 77 30 eyes eye NNS cord-012719-5qa0e4xt 77 31 was be VBD cord-012719-5qa0e4xt 77 32 slightly slightly RB cord-012719-5qa0e4xt 77 33 thinner thin JJR cord-012719-5qa0e4xt 77 34 than than IN cord-012719-5qa0e4xt 77 35 that that DT cord-012719-5qa0e4xt 77 36 of of IN cord-012719-5qa0e4xt 77 37 controls control NNS cord-012719-5qa0e4xt 77 38 ( ( -LRB- cord-012719-5qa0e4xt 77 39 P p NN cord-012719-5qa0e4xt 77 40 = = SYM cord-012719-5qa0e4xt 77 41 0.014 0.014 CD cord-012719-5qa0e4xt 77 42 ) ) -RRB- cord-012719-5qa0e4xt 77 43 . . . cord-012719-5qa0e4xt 78 1 In in IN cord-012719-5qa0e4xt 78 2 particular particular JJ cord-012719-5qa0e4xt 78 3 , , , cord-012719-5qa0e4xt 78 4 the the DT cord-012719-5qa0e4xt 78 5 superior superior JJ cord-012719-5qa0e4xt 78 6 quadrant quadrant JJ cord-012719-5qa0e4xt 78 7 RNFL RNFL NNP cord-012719-5qa0e4xt 78 8 thickness thickness NN cord-012719-5qa0e4xt 78 9 of of IN cord-012719-5qa0e4xt 78 10 XFS xfs NN cord-012719-5qa0e4xt 78 11 - - HYPH cord-012719-5qa0e4xt 78 12 affected affect VBN cord-012719-5qa0e4xt 78 13 eyes eye NNS cord-012719-5qa0e4xt 78 14 ( ( -LRB- cord-012719-5qa0e4xt 78 15 108.5 108.5 CD cord-012719-5qa0e4xt 78 16 ± ± CD cord-012719-5qa0e4xt 78 17 13.5 13.5 CD cord-012719-5qa0e4xt 78 18 μm μm NNS cord-012719-5qa0e4xt 78 19 ) ) -RRB- cord-012719-5qa0e4xt 78 20 was be VBD cord-012719-5qa0e4xt 78 21 thinner thin JJR cord-012719-5qa0e4xt 78 22 than than IN cord-012719-5qa0e4xt 78 23 that that DT cord-012719-5qa0e4xt 78 24 of of IN cord-012719-5qa0e4xt 78 25 controls control NNS cord-012719-5qa0e4xt 78 26 ( ( -LRB- cord-012719-5qa0e4xt 78 27 114.3 114.3 CD cord-012719-5qa0e4xt 78 28 ± ± CD cord-012719-5qa0e4xt 78 29 12.2 12.2 CD cord-012719-5qa0e4xt 78 30 μm μm NNS cord-012719-5qa0e4xt 78 31 ) ) -RRB- cord-012719-5qa0e4xt 78 32 ( ( -LRB- cord-012719-5qa0e4xt 78 33 P p NN cord-012719-5qa0e4xt 78 34 = = SYM cord-012719-5qa0e4xt 78 35 0.002 0.002 CD cord-012719-5qa0e4xt 78 36 by by IN cord-012719-5qa0e4xt 78 37 ANOVA ANOVA NNP cord-012719-5qa0e4xt 78 38 ; ; : cord-012719-5qa0e4xt 78 39 P p NN cord-012719-5qa0e4xt 78 40 = = SYM cord-012719-5qa0e4xt 78 41 0.001 0.001 CD cord-012719-5qa0e4xt 78 42 by by IN cord-012719-5qa0e4xt 78 43 Tukey Tukey NNP cord-012719-5qa0e4xt 78 44 's 's POS cord-012719-5qa0e4xt 78 45 post post JJ cord-012719-5qa0e4xt 78 46 - - JJ cord-012719-5qa0e4xt 78 47 hoc hoc JJ cord-012719-5qa0e4xt 78 48 test test NN cord-012719-5qa0e4xt 78 49 ) ) -RRB- cord-012719-5qa0e4xt 78 50 . . . cord-012719-5qa0e4xt 79 1 GCC gcc NN cord-012719-5qa0e4xt 79 2 parameters parameter NNS cord-012719-5qa0e4xt 79 3 are be VBP cord-012719-5qa0e4xt 79 4 summarized summarize VBN cord-012719-5qa0e4xt 79 5 in in IN cord-012719-5qa0e4xt 79 6 Table Table NNP cord-012719-5qa0e4xt 79 7 3 3 CD cord-012719-5qa0e4xt 79 8 . . . cord-012719-5qa0e4xt 80 1 There there EX cord-012719-5qa0e4xt 80 2 was be VBD cord-012719-5qa0e4xt 80 3 a a DT cord-012719-5qa0e4xt 80 4 significant significant JJ cord-012719-5qa0e4xt 80 5 difference difference NN cord-012719-5qa0e4xt 80 6 in in IN cord-012719-5qa0e4xt 80 7 the the DT cord-012719-5qa0e4xt 80 8 average average JJ cord-012719-5qa0e4xt 80 9 and and CC cord-012719-5qa0e4xt 80 10 superior superior JJ cord-012719-5qa0e4xt 80 11 GCC gcc NN cord-012719-5qa0e4xt 80 12 parameters parameter NNS cord-012719-5qa0e4xt 80 13 between between IN cord-012719-5qa0e4xt 80 14 groups group NNS cord-012719-5qa0e4xt 80 15 by by IN cord-012719-5qa0e4xt 80 16 one one CD cord-012719-5qa0e4xt 80 17 - - HYPH cord-012719-5qa0e4xt 80 18 way way NN cord-012719-5qa0e4xt 80 19 ANOVA ANOVA NNP cord-012719-5qa0e4xt 80 20 ( ( -LRB- cord-012719-5qa0e4xt 80 21 P p NN cord-012719-5qa0e4xt 80 22 = = SYM cord-012719-5qa0e4xt 80 23 0.032 0.032 CD cord-012719-5qa0e4xt 80 24 , , , cord-012719-5qa0e4xt 80 25 P p NN cord-012719-5qa0e4xt 80 26 = = SYM cord-012719-5qa0e4xt 80 27 0.002 0.002 CD cord-012719-5qa0e4xt 80 28 , , , cord-012719-5qa0e4xt 80 29 respectively respectively RB cord-012719-5qa0e4xt 80 30 ) ) -RRB- cord-012719-5qa0e4xt 80 31 . . . cord-012719-5qa0e4xt 81 1 In in IN cord-012719-5qa0e4xt 81 2 particular particular JJ cord-012719-5qa0e4xt 81 3 , , , cord-012719-5qa0e4xt 81 4 the the DT cord-012719-5qa0e4xt 81 5 superior superior JJ cord-012719-5qa0e4xt 81 6 GCC GCC NNP cord-012719-5qa0e4xt 81 7 thickness thickness NN cord-012719-5qa0e4xt 81 8 decreased decrease VBD cord-012719-5qa0e4xt 81 9 in in IN cord-012719-5qa0e4xt 81 10 both both DT cord-012719-5qa0e4xt 81 11 XFS xfs NN cord-012719-5qa0e4xt 81 12 - - HYPH cord-012719-5qa0e4xt 81 13 affected affect VBN cord-012719-5qa0e4xt 81 14 eyes eye NNS cord-012719-5qa0e4xt 81 15 and and CC cord-012719-5qa0e4xt 81 16 fellow fellow JJ cord-012719-5qa0e4xt 81 17 eyes eye NNS cord-012719-5qa0e4xt 81 18 ( ( -LRB- cord-012719-5qa0e4xt 81 19 86.1 86.1 CD cord-012719-5qa0e4xt 81 20 ± ± CD cord-012719-5qa0e4xt 81 21 6.5 6.5 CD cord-012719-5qa0e4xt 81 22 μm μm NNS cord-012719-5qa0e4xt 81 23 , , , cord-012719-5qa0e4xt 81 24 87.8 87.8 CD cord-012719-5qa0e4xt 81 25 ± ± NNP cord-012719-5qa0e4xt 81 26 6.3 6.3 CD cord-012719-5qa0e4xt 81 27 μm μm NNS cord-012719-5qa0e4xt 81 28 , , , cord-012719-5qa0e4xt 81 29 respectively respectively RB cord-012719-5qa0e4xt 81 30 ) ) -RRB- cord-012719-5qa0e4xt 81 31 as as IN cord-012719-5qa0e4xt 81 32 compared compare VBN cord-012719-5qa0e4xt 81 33 with with IN cord-012719-5qa0e4xt 81 34 healthy healthy JJ cord-012719-5qa0e4xt 81 35 controls control NNS cord-012719-5qa0e4xt 81 36 ( ( -LRB- cord-012719-5qa0e4xt 81 37 94.6 94.6 CD cord-012719-5qa0e4xt 81 38 ± ± CD cord-012719-5qa0e4xt 81 39 5.7 5.7 CD cord-012719-5qa0e4xt 81 40 μm μm NNS cord-012719-5qa0e4xt 81 41 ) ) -RRB- cord-012719-5qa0e4xt 82 1 ( ( -LRB- cord-012719-5qa0e4xt 82 2 P p NN cord-012719-5qa0e4xt 82 3 = = SYM cord-012719-5qa0e4xt 82 4 0.001 0.001 CD cord-012719-5qa0e4xt 82 5 , , , cord-012719-5qa0e4xt 82 6 P p NN cord-012719-5qa0e4xt 82 7 = = SYM cord-012719-5qa0e4xt 82 8 0.004 0.004 CD cord-012719-5qa0e4xt 82 9 , , , cord-012719-5qa0e4xt 82 10 respectively respectively RB cord-012719-5qa0e4xt 82 11 , , , cord-012719-5qa0e4xt 82 12 by by IN cord-012719-5qa0e4xt 82 13 Tukey Tukey NNP cord-012719-5qa0e4xt 82 14 's 's POS cord-012719-5qa0e4xt 82 15 test test NN cord-012719-5qa0e4xt 82 16 ) ) -RRB- cord-012719-5qa0e4xt 82 17 . . . cord-012719-5qa0e4xt 83 1 However however RB cord-012719-5qa0e4xt 83 2 , , , cord-012719-5qa0e4xt 83 3 the the DT cord-012719-5qa0e4xt 83 4 inferior inferior JJ cord-012719-5qa0e4xt 83 5 quadrant quadrant NN cord-012719-5qa0e4xt 83 6 GCC GCC NNP cord-012719-5qa0e4xt 83 7 thickness thickness NN cord-012719-5qa0e4xt 83 8 did do VBD cord-012719-5qa0e4xt 83 9 not not RB cord-012719-5qa0e4xt 83 10 show show VB cord-012719-5qa0e4xt 83 11 a a DT cord-012719-5qa0e4xt 83 12 statistically statistically RB cord-012719-5qa0e4xt 83 13 significant significant JJ cord-012719-5qa0e4xt 83 14 difference difference NN cord-012719-5qa0e4xt 83 15 between between IN cord-012719-5qa0e4xt 83 16 three three CD cord-012719-5qa0e4xt 83 17 groups group NNS cord-012719-5qa0e4xt 83 18 ( ( -LRB- cord-012719-5qa0e4xt 83 19 P p NN cord-012719-5qa0e4xt 83 20 = = SYM cord-012719-5qa0e4xt 83 21 0.125 0.125 CD cord-012719-5qa0e4xt 83 22 ) ) -RRB- cord-012719-5qa0e4xt 83 23 . . . cord-012719-5qa0e4xt 84 1 RNFL RNFL NNP cord-012719-5qa0e4xt 84 2 and and CC cord-012719-5qa0e4xt 84 3 GCC GCC NNP cord-012719-5qa0e4xt 84 4 thickness thickness NN cord-012719-5qa0e4xt 84 5 measurements measurement NNS cord-012719-5qa0e4xt 84 6 provide provide VBP cord-012719-5qa0e4xt 84 7 clinically clinically RB cord-012719-5qa0e4xt 84 8 important important JJ cord-012719-5qa0e4xt 84 9 information information NN cord-012719-5qa0e4xt 84 10 about about IN cord-012719-5qa0e4xt 84 11 early early JJ cord-012719-5qa0e4xt 84 12 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 84 13 changes change NNS cord-012719-5qa0e4xt 84 14 [ [ -LRB- cord-012719-5qa0e4xt 84 15 17 17 CD cord-012719-5qa0e4xt 84 16 ] ] -RRB- cord-012719-5qa0e4xt 84 17 . . . cord-012719-5qa0e4xt 85 1 However however RB cord-012719-5qa0e4xt 85 2 , , , cord-012719-5qa0e4xt 85 3 few few JJ cord-012719-5qa0e4xt 85 4 studies study NNS cord-012719-5qa0e4xt 85 5 have have VBP cord-012719-5qa0e4xt 85 6 compared compare VBN cord-012719-5qa0e4xt 85 7 the the DT cord-012719-5qa0e4xt 85 8 RNFL RNFL NNP cord-012719-5qa0e4xt 85 9 and and CC cord-012719-5qa0e4xt 85 10 GCC GCC NNP cord-012719-5qa0e4xt 85 11 thicknesses thickness NNS cord-012719-5qa0e4xt 85 12 between between IN cord-012719-5qa0e4xt 85 13 patients patient NNS cord-012719-5qa0e4xt 85 14 with with IN cord-012719-5qa0e4xt 85 15 XFS XFS NNP cord-012719-5qa0e4xt 85 16 without without IN cord-012719-5qa0e4xt 85 17 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 85 18 damage damage NN cord-012719-5qa0e4xt 85 19 and and CC cord-012719-5qa0e4xt 85 20 healthy healthy JJ cord-012719-5qa0e4xt 85 21 controls control NNS cord-012719-5qa0e4xt 85 22 [ [ -LRB- cord-012719-5qa0e4xt 85 23 12 12 CD cord-012719-5qa0e4xt 85 24 , , , cord-012719-5qa0e4xt 85 25 15 15 CD cord-012719-5qa0e4xt 85 26 ] ] -RRB- cord-012719-5qa0e4xt 85 27 . . . cord-012719-5qa0e4xt 86 1 In in IN cord-012719-5qa0e4xt 86 2 the the DT cord-012719-5qa0e4xt 86 3 present present JJ cord-012719-5qa0e4xt 86 4 study study NN cord-012719-5qa0e4xt 86 5 , , , cord-012719-5qa0e4xt 86 6 patients patient NNS cord-012719-5qa0e4xt 86 7 with with IN cord-012719-5qa0e4xt 86 8 unilateral unilateral JJ cord-012719-5qa0e4xt 86 9 XFS xfs NN cord-012719-5qa0e4xt 86 10 without without IN cord-012719-5qa0e4xt 86 11 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 86 12 optic optic JJ cord-012719-5qa0e4xt 86 13 nerve nerve NN cord-012719-5qa0e4xt 86 14 changes change NNS cord-012719-5qa0e4xt 86 15 or or CC cord-012719-5qa0e4xt 86 16 visual visual JJ cord-012719-5qa0e4xt 86 17 field field NN cord-012719-5qa0e4xt 86 18 defects defect NNS cord-012719-5qa0e4xt 86 19 showed show VBD cord-012719-5qa0e4xt 86 20 thinner thin JJR cord-012719-5qa0e4xt 86 21 RNFL RNFL NNP cord-012719-5qa0e4xt 86 22 and and CC cord-012719-5qa0e4xt 86 23 GCC GCC NNP cord-012719-5qa0e4xt 86 24 thicknesses thickness NNS cord-012719-5qa0e4xt 86 25 than than IN cord-012719-5qa0e4xt 86 26 those those DT cord-012719-5qa0e4xt 86 27 of of IN cord-012719-5qa0e4xt 86 28 control control NN cord-012719-5qa0e4xt 86 29 individuals individual NNS cord-012719-5qa0e4xt 86 30 . . . cord-012719-5qa0e4xt 87 1 Our -PRON- PRP$ cord-012719-5qa0e4xt 87 2 results result NNS cord-012719-5qa0e4xt 87 3 were be VBD cord-012719-5qa0e4xt 87 4 similar similar JJ cord-012719-5qa0e4xt 87 5 to to IN cord-012719-5qa0e4xt 87 6 those those DT cord-012719-5qa0e4xt 87 7 of of IN cord-012719-5qa0e4xt 87 8 previous previous JJ cord-012719-5qa0e4xt 87 9 individual individual JJ cord-012719-5qa0e4xt 87 10 studies study NNS cord-012719-5qa0e4xt 87 11 and and CC cord-012719-5qa0e4xt 87 12 meta meta NNP cord-012719-5qa0e4xt 87 13 - - HYPH cord-012719-5qa0e4xt 87 14 analysis analysis NN cord-012719-5qa0e4xt 87 15 [ [ -LRB- cord-012719-5qa0e4xt 87 16 12 12 CD cord-012719-5qa0e4xt 87 17 , , , cord-012719-5qa0e4xt 87 18 15 15 CD cord-012719-5qa0e4xt 87 19 , , , cord-012719-5qa0e4xt 87 20 18 18 CD cord-012719-5qa0e4xt 87 21 ] ] -RRB- cord-012719-5qa0e4xt 87 22 . . . cord-012719-5qa0e4xt 88 1 Our -PRON- PRP$ cord-012719-5qa0e4xt 88 2 study study NN cord-012719-5qa0e4xt 88 3 demonstrated demonstrate VBD cord-012719-5qa0e4xt 88 4 reduced reduce VBN cord-012719-5qa0e4xt 88 5 RNFL RNFL NNP cord-012719-5qa0e4xt 88 6 and and CC cord-012719-5qa0e4xt 88 7 GCC GCC NNP cord-012719-5qa0e4xt 88 8 thicknesses thickness NNS cord-012719-5qa0e4xt 88 9 in in IN cord-012719-5qa0e4xt 88 10 superior superior JJ cord-012719-5qa0e4xt 88 11 quadrants quadrant NNS cord-012719-5qa0e4xt 88 12 . . . cord-012719-5qa0e4xt 89 1 Similarly similarly RB cord-012719-5qa0e4xt 89 2 , , , cord-012719-5qa0e4xt 89 3 Aydin Aydin NNP cord-012719-5qa0e4xt 89 4 et et NNP cord-012719-5qa0e4xt 89 5 al al NNP cord-012719-5qa0e4xt 89 6 . . . cord-012719-5qa0e4xt 90 1 [ [ -LRB- cord-012719-5qa0e4xt 90 2 12 12 CD cord-012719-5qa0e4xt 90 3 ] ] -RRB- cord-012719-5qa0e4xt 90 4 found find VBD cord-012719-5qa0e4xt 90 5 that that IN cord-012719-5qa0e4xt 90 6 RNFL RNFL NNP cord-012719-5qa0e4xt 90 7 thickness thickness NN cord-012719-5qa0e4xt 90 8 in in IN cord-012719-5qa0e4xt 90 9 the the DT cord-012719-5qa0e4xt 90 10 superior superior JJ cord-012719-5qa0e4xt 90 11 quadrant quadrant NN cord-012719-5qa0e4xt 90 12 was be VBD cord-012719-5qa0e4xt 90 13 thinner thin JJR cord-012719-5qa0e4xt 90 14 in in IN cord-012719-5qa0e4xt 90 15 XFS xfs JJ cord-012719-5qa0e4xt 90 16 patients patient NNS cord-012719-5qa0e4xt 90 17 than than IN cord-012719-5qa0e4xt 90 18 in in IN cord-012719-5qa0e4xt 90 19 healthy healthy JJ cord-012719-5qa0e4xt 90 20 subjects subject NNS cord-012719-5qa0e4xt 90 21 using use VBG cord-012719-5qa0e4xt 90 22 Cirrus Cirrus NNP cord-012719-5qa0e4xt 90 23 HD HD NNP cord-012719-5qa0e4xt 90 24 OCT-4000 OCT-4000 NNP cord-012719-5qa0e4xt 90 25 . . . cord-012719-5qa0e4xt 91 1 They -PRON- PRP cord-012719-5qa0e4xt 91 2 reported report VBD cord-012719-5qa0e4xt 91 3 the the DT cord-012719-5qa0e4xt 91 4 GCC GCC NNP cord-012719-5qa0e4xt 91 5 thickness thickness NN cord-012719-5qa0e4xt 91 6 was be VBD cord-012719-5qa0e4xt 91 7 thinner thin JJR cord-012719-5qa0e4xt 91 8 in in IN cord-012719-5qa0e4xt 91 9 XFS xfs JJ cord-012719-5qa0e4xt 91 10 patients patient NNS cord-012719-5qa0e4xt 91 11 than than IN cord-012719-5qa0e4xt 91 12 in in IN cord-012719-5qa0e4xt 91 13 healthy healthy JJ cord-012719-5qa0e4xt 91 14 subjects subject NNS cord-012719-5qa0e4xt 91 15 , , , cord-012719-5qa0e4xt 91 16 except except IN cord-012719-5qa0e4xt 91 17 in in IN cord-012719-5qa0e4xt 91 18 the the DT cord-012719-5qa0e4xt 91 19 inferior inferior JJ cord-012719-5qa0e4xt 91 20 and and CC cord-012719-5qa0e4xt 91 21 inferonasal inferonasal NNP cord-012719-5qa0e4xt 91 22 quadrants quadrant NNS cord-012719-5qa0e4xt 91 23 . . . cord-012719-5qa0e4xt 92 1 In in IN cord-012719-5qa0e4xt 92 2 addition addition NN cord-012719-5qa0e4xt 92 3 , , , cord-012719-5qa0e4xt 92 4 Eltutar Eltutar NNP cord-012719-5qa0e4xt 92 5 et et NNP cord-012719-5qa0e4xt 92 6 al al NNP cord-012719-5qa0e4xt 92 7 . . . cord-012719-5qa0e4xt 93 1 [ [ -LRB- cord-012719-5qa0e4xt 93 2 15 15 CD cord-012719-5qa0e4xt 93 3 ] ] -RRB- cord-012719-5qa0e4xt 93 4 reported report VBD cord-012719-5qa0e4xt 93 5 that that IN cord-012719-5qa0e4xt 93 6 in in IN cord-012719-5qa0e4xt 93 7 eyes eye NNS cord-012719-5qa0e4xt 93 8 of of IN cord-012719-5qa0e4xt 93 9 XFS XFS NNP cord-012719-5qa0e4xt 93 10 , , , cord-012719-5qa0e4xt 93 11 the the DT cord-012719-5qa0e4xt 93 12 superior superior JJ cord-012719-5qa0e4xt 93 13 and and CC cord-012719-5qa0e4xt 93 14 total total JJ cord-012719-5qa0e4xt 93 15 macular macular JJ cord-012719-5qa0e4xt 93 16 NFL NFL NNP cord-012719-5qa0e4xt 93 17 ( ( -LRB- cord-012719-5qa0e4xt 93 18 nerve nerve NN cord-012719-5qa0e4xt 93 19 fiber fiber NN cord-012719-5qa0e4xt 93 20 layer layer NN cord-012719-5qa0e4xt 93 21 ) ) -RRB- cord-012719-5qa0e4xt 93 22 thickness thickness NN cord-012719-5qa0e4xt 93 23 ; ; : cord-012719-5qa0e4xt 93 24 superior superior JJ cord-012719-5qa0e4xt 93 25 and and CC cord-012719-5qa0e4xt 93 26 total total JJ cord-012719-5qa0e4xt 93 27 GCL GCL NNP cord-012719-5qa0e4xt 93 28 + + CC cord-012719-5qa0e4xt 93 29 IPL IPL NNP cord-012719-5qa0e4xt 93 30 ( ( -LRB- cord-012719-5qa0e4xt 93 31 ganglion ganglion NN cord-012719-5qa0e4xt 93 32 cell cell NN cord-012719-5qa0e4xt 93 33 layer layer NN cord-012719-5qa0e4xt 93 34 + + CC cord-012719-5qa0e4xt 93 35 inner inner JJ cord-012719-5qa0e4xt 93 36 plexiform plexiform NNS cord-012719-5qa0e4xt 93 37 layer layer NN cord-012719-5qa0e4xt 93 38 ) ) -RRB- cord-012719-5qa0e4xt 93 39 thickness thickness NN cord-012719-5qa0e4xt 93 40 were be VBD cord-012719-5qa0e4xt 93 41 significantly significantly RB cord-012719-5qa0e4xt 93 42 thinner thin JJR cord-012719-5qa0e4xt 93 43 than than IN cord-012719-5qa0e4xt 93 44 those those DT cord-012719-5qa0e4xt 93 45 of of IN cord-012719-5qa0e4xt 93 46 control control NN cord-012719-5qa0e4xt 93 47 subject subject NN cord-012719-5qa0e4xt 93 48 . . . cord-012719-5qa0e4xt 94 1 However however RB cord-012719-5qa0e4xt 94 2 , , , cord-012719-5qa0e4xt 94 3 controversies controversy NNS cord-012719-5qa0e4xt 94 4 regarding regard VBG cord-012719-5qa0e4xt 94 5 location location NN cord-012719-5qa0e4xt 94 6 of of IN cord-012719-5qa0e4xt 94 7 thinning thin VBG cord-012719-5qa0e4xt 94 8 still still RB cord-012719-5qa0e4xt 94 9 abound abound VBP cord-012719-5qa0e4xt 94 10 . . . cord-012719-5qa0e4xt 95 1 Previous previous JJ cord-012719-5qa0e4xt 95 2 meta meta JJ cord-012719-5qa0e4xt 95 3 - - HYPH cord-012719-5qa0e4xt 95 4 analysis analysis NN cord-012719-5qa0e4xt 95 5 showed show VBD cord-012719-5qa0e4xt 95 6 that that IN cord-012719-5qa0e4xt 95 7 RNFL RNFL NNP cord-012719-5qa0e4xt 95 8 thickness thickness NN cord-012719-5qa0e4xt 95 9 was be VBD cord-012719-5qa0e4xt 95 10 significantly significantly RB cord-012719-5qa0e4xt 95 11 lower low JJR cord-012719-5qa0e4xt 95 12 in in IN cord-012719-5qa0e4xt 95 13 all all DT cord-012719-5qa0e4xt 95 14 quadrants quadrant NNS cord-012719-5qa0e4xt 95 15 in in IN cord-012719-5qa0e4xt 95 16 XFS xfs JJ cord-012719-5qa0e4xt 95 17 patients patient NNS cord-012719-5qa0e4xt 95 18 compared compare VBN cord-012719-5qa0e4xt 95 19 with with IN cord-012719-5qa0e4xt 95 20 control control NN cord-012719-5qa0e4xt 95 21 group group NN cord-012719-5qa0e4xt 95 22 [ [ -LRB- cord-012719-5qa0e4xt 95 23 18 18 CD cord-012719-5qa0e4xt 95 24 ] ] -RRB- cord-012719-5qa0e4xt 95 25 . . . cord-012719-5qa0e4xt 96 1 In in IN cord-012719-5qa0e4xt 96 2 their -PRON- PRP$ cord-012719-5qa0e4xt 96 3 study study NN cord-012719-5qa0e4xt 96 4 , , , cord-012719-5qa0e4xt 96 5 the the DT cord-012719-5qa0e4xt 96 6 weighted weighted JJ cord-012719-5qa0e4xt 96 7 mean mean JJ cord-012719-5qa0e4xt 96 8 difference difference NN cord-012719-5qa0e4xt 96 9 was be VBD cord-012719-5qa0e4xt 96 10 −10.68 −10.68 : cord-012719-5qa0e4xt 96 11 in in IN cord-012719-5qa0e4xt 96 12 superior superior JJ cord-012719-5qa0e4xt 96 13 , , , cord-012719-5qa0e4xt 97 1 −8.20 −8.20 NNP cord-012719-5qa0e4xt 97 2 in in IN cord-012719-5qa0e4xt 97 3 inferior inferior JJ cord-012719-5qa0e4xt 97 4 , , , cord-012719-5qa0e4xt 97 5 −6.39 −6.39 NNP cord-012719-5qa0e4xt 97 6 in in IN cord-012719-5qa0e4xt 97 7 temporal temporal JJ cord-012719-5qa0e4xt 97 8 , , , cord-012719-5qa0e4xt 97 9 and and CC cord-012719-5qa0e4xt 97 10 −3.05 −3.05 NNP cord-012719-5qa0e4xt 97 11 in in IN cord-012719-5qa0e4xt 97 12 nasal nasal NN cord-012719-5qa0e4xt 97 13 quadrants quadrant NNS cord-012719-5qa0e4xt 97 14 [ [ -LRB- cord-012719-5qa0e4xt 97 15 18 18 CD cord-012719-5qa0e4xt 97 16 ] ] -RRB- cord-012719-5qa0e4xt 97 17 . . . cord-012719-5qa0e4xt 98 1 Subgroup Subgroup NNP cord-012719-5qa0e4xt 98 2 analysis analysis NN cord-012719-5qa0e4xt 98 3 demonstrated demonstrate VBD cord-012719-5qa0e4xt 98 4 no no DT cord-012719-5qa0e4xt 98 5 significant significant JJ cord-012719-5qa0e4xt 98 6 differences difference NNS cord-012719-5qa0e4xt 98 7 in in IN cord-012719-5qa0e4xt 98 8 the the DT cord-012719-5qa0e4xt 98 9 nasal nasal NN cord-012719-5qa0e4xt 98 10 quadrant quadrant NN cord-012719-5qa0e4xt 98 11 regardless regardless RB cord-012719-5qa0e4xt 98 12 of of IN cord-012719-5qa0e4xt 98 13 OCT OCT NNP cord-012719-5qa0e4xt 98 14 type type NN cord-012719-5qa0e4xt 98 15 in in IN cord-012719-5qa0e4xt 98 16 their -PRON- PRP$ cord-012719-5qa0e4xt 98 17 study study NN cord-012719-5qa0e4xt 98 18 [ [ -LRB- cord-012719-5qa0e4xt 98 19 18 18 CD cord-012719-5qa0e4xt 98 20 ] ] -RRB- cord-012719-5qa0e4xt 98 21 . . . cord-012719-5qa0e4xt 99 1 Moreover moreover RB cord-012719-5qa0e4xt 99 2 , , , cord-012719-5qa0e4xt 99 3 publication publication NN cord-012719-5qa0e4xt 99 4 bias bias NN cord-012719-5qa0e4xt 99 5 was be VBD cord-012719-5qa0e4xt 99 6 found find VBN cord-012719-5qa0e4xt 99 7 in in IN cord-012719-5qa0e4xt 99 8 average average JJ cord-012719-5qa0e4xt 99 9 RNFL RNFL NNP cord-012719-5qa0e4xt 99 10 thickness thickness NN cord-012719-5qa0e4xt 99 11 and and CC cord-012719-5qa0e4xt 99 12 inferior inferior JJ cord-012719-5qa0e4xt 99 13 RNFL RNFL NNP cord-012719-5qa0e4xt 99 14 thickness thickness NN cord-012719-5qa0e4xt 99 15 [ [ -LRB- cord-012719-5qa0e4xt 99 16 18 18 CD cord-012719-5qa0e4xt 99 17 ] ] -RRB- cord-012719-5qa0e4xt 99 18 . . . cord-012719-5qa0e4xt 100 1 Thus thus RB cord-012719-5qa0e4xt 100 2 , , , cord-012719-5qa0e4xt 100 3 their -PRON- PRP$ cord-012719-5qa0e4xt 100 4 results result NNS cord-012719-5qa0e4xt 100 5 seem seem VBP cord-012719-5qa0e4xt 100 6 similar similar JJ cord-012719-5qa0e4xt 100 7 to to IN cord-012719-5qa0e4xt 100 8 our -PRON- PRP$ cord-012719-5qa0e4xt 100 9 own own JJ cord-012719-5qa0e4xt 100 10 . . . cord-012719-5qa0e4xt 101 1 These these DT cord-012719-5qa0e4xt 101 2 variations variation NNS cord-012719-5qa0e4xt 101 3 in in IN cord-012719-5qa0e4xt 101 4 measurements measurement NNS cord-012719-5qa0e4xt 101 5 may may MD cord-012719-5qa0e4xt 101 6 be be VB cord-012719-5qa0e4xt 101 7 attributable attributable JJ cord-012719-5qa0e4xt 101 8 to to IN cord-012719-5qa0e4xt 101 9 the the DT cord-012719-5qa0e4xt 101 10 small small JJ cord-012719-5qa0e4xt 101 11 sample sample NN cord-012719-5qa0e4xt 101 12 size size NN cord-012719-5qa0e4xt 101 13 , , , cord-012719-5qa0e4xt 101 14 different different JJ cord-012719-5qa0e4xt 101 15 ethnicities ethnicity NNS cord-012719-5qa0e4xt 101 16 , , , cord-012719-5qa0e4xt 101 17 and and CC cord-012719-5qa0e4xt 101 18 possible possible JJ cord-012719-5qa0e4xt 101 19 systemic systemic JJ cord-012719-5qa0e4xt 101 20 diseases disease NNS cord-012719-5qa0e4xt 101 21 of of IN cord-012719-5qa0e4xt 101 22 the the DT cord-012719-5qa0e4xt 101 23 study study NN cord-012719-5qa0e4xt 101 24 participants participant NNS cord-012719-5qa0e4xt 101 25 , , , cord-012719-5qa0e4xt 101 26 and and CC cord-012719-5qa0e4xt 101 27 this this DT cord-012719-5qa0e4xt 101 28 was be VBD cord-012719-5qa0e4xt 101 29 the the DT cord-012719-5qa0e4xt 101 30 first first JJ cord-012719-5qa0e4xt 101 31 study study NN cord-012719-5qa0e4xt 101 32 comparing compare VBG cord-012719-5qa0e4xt 101 33 the the DT cord-012719-5qa0e4xt 101 34 RNFL RNFL NNP cord-012719-5qa0e4xt 101 35 thickness thickness NN cord-012719-5qa0e4xt 101 36 using use VBG cord-012719-5qa0e4xt 101 37 Optovue Optovue NNP cord-012719-5qa0e4xt 101 38 SD SD NNP cord-012719-5qa0e4xt 101 39 - - HYPH cord-012719-5qa0e4xt 101 40 OCT OCT NNP cord-012719-5qa0e4xt 102 1 The the DT cord-012719-5qa0e4xt 102 2 reasons reason NNS cord-012719-5qa0e4xt 102 3 for for IN cord-012719-5qa0e4xt 102 4 superior superior JJ cord-012719-5qa0e4xt 102 5 thinning thinning NN cord-012719-5qa0e4xt 102 6 of of IN cord-012719-5qa0e4xt 102 7 RNFL RNFL NNP cord-012719-5qa0e4xt 102 8 thickness thickness NN cord-012719-5qa0e4xt 102 9 may may MD cord-012719-5qa0e4xt 102 10 be be VB cord-012719-5qa0e4xt 102 11 attributable attributable JJ cord-012719-5qa0e4xt 102 12 to to IN cord-012719-5qa0e4xt 102 13 vascular vascular JJ cord-012719-5qa0e4xt 102 14 factors factor NNS cord-012719-5qa0e4xt 102 15 besides besides IN cord-012719-5qa0e4xt 102 16 IOP IOP NNP cord-012719-5qa0e4xt 102 17 . . . cord-012719-5qa0e4xt 103 1 Recent recent JJ cord-012719-5qa0e4xt 103 2 OCTA OCTA NNP cord-012719-5qa0e4xt 103 3 studies study NNS cord-012719-5qa0e4xt 103 4 have have VBP cord-012719-5qa0e4xt 103 5 shown show VBN cord-012719-5qa0e4xt 103 6 that that IN cord-012719-5qa0e4xt 103 7 superficial superficial JJ cord-012719-5qa0e4xt 103 8 capillary capillary JJ cord-012719-5qa0e4xt 103 9 density density NN cord-012719-5qa0e4xt 103 10 is be VBZ cord-012719-5qa0e4xt 103 11 significantly significantly RB cord-012719-5qa0e4xt 103 12 lower low JJR cord-012719-5qa0e4xt 103 13 in in IN cord-012719-5qa0e4xt 103 14 the the DT cord-012719-5qa0e4xt 103 15 superior superior JJ cord-012719-5qa0e4xt 103 16 quadrant quadrant NN cord-012719-5qa0e4xt 103 17 , , , cord-012719-5qa0e4xt 103 18 but but CC cord-012719-5qa0e4xt 103 19 not not RB cord-012719-5qa0e4xt 103 20 in in IN cord-012719-5qa0e4xt 103 21 the the DT cord-012719-5qa0e4xt 103 22 inferior inferior JJ cord-012719-5qa0e4xt 103 23 quadrant quadrant NN cord-012719-5qa0e4xt 103 24 [ [ -LRB- cord-012719-5qa0e4xt 103 25 19 19 CD cord-012719-5qa0e4xt 103 26 ] ] -RRB- cord-012719-5qa0e4xt 103 27 . . . cord-012719-5qa0e4xt 104 1 These these DT cord-012719-5qa0e4xt 104 2 vascular vascular JJ cord-012719-5qa0e4xt 104 3 differences difference NNS cord-012719-5qa0e4xt 104 4 were be VBD cord-012719-5qa0e4xt 104 5 supported support VBN cord-012719-5qa0e4xt 104 6 by by IN cord-012719-5qa0e4xt 104 7 some some DT cord-012719-5qa0e4xt 104 8 studies study NNS cord-012719-5qa0e4xt 104 9 that that WDT cord-012719-5qa0e4xt 104 10 report report VBP cord-012719-5qa0e4xt 104 11 reduced reduce VBD cord-012719-5qa0e4xt 104 12 RNFL RNFL NNP cord-012719-5qa0e4xt 104 13 thickness thickness NN cord-012719-5qa0e4xt 104 14 in in IN cord-012719-5qa0e4xt 104 15 XFS xfs JJ cord-012719-5qa0e4xt 104 16 patients patient NNS cord-012719-5qa0e4xt 104 17 with with IN cord-012719-5qa0e4xt 104 18 normal normal JJ cord-012719-5qa0e4xt 104 19 IOP IOP NNP cord-012719-5qa0e4xt 104 20 [ [ -LRB- cord-012719-5qa0e4xt 104 21 20 20 CD cord-012719-5qa0e4xt 104 22 , , , cord-012719-5qa0e4xt 104 23 21 21 CD cord-012719-5qa0e4xt 104 24 ] ] -RRB- cord-012719-5qa0e4xt 104 25 . . . cord-012719-5qa0e4xt 105 1 It -PRON- PRP cord-012719-5qa0e4xt 105 2 has have VBZ cord-012719-5qa0e4xt 105 3 , , , cord-012719-5qa0e4xt 105 4 therefore therefore RB cord-012719-5qa0e4xt 105 5 , , , cord-012719-5qa0e4xt 105 6 been be VBN cord-012719-5qa0e4xt 105 7 suggested suggest VBN cord-012719-5qa0e4xt 105 8 that that IN cord-012719-5qa0e4xt 105 9 RNFL RNFL NNP cord-012719-5qa0e4xt 105 10 changes change NNS cord-012719-5qa0e4xt 105 11 in in IN cord-012719-5qa0e4xt 105 12 XFS xfs JJ cord-012719-5qa0e4xt 105 13 patients patient NNS cord-012719-5qa0e4xt 105 14 are be VBP cord-012719-5qa0e4xt 105 15 not not RB cord-012719-5qa0e4xt 105 16 only only RB cord-012719-5qa0e4xt 105 17 caused cause VBN cord-012719-5qa0e4xt 105 18 by by IN cord-012719-5qa0e4xt 105 19 high high JJ cord-012719-5qa0e4xt 105 20 IOP IOP NNP cord-012719-5qa0e4xt 105 21 but but CC cord-012719-5qa0e4xt 105 22 also also RB cord-012719-5qa0e4xt 105 23 by by IN cord-012719-5qa0e4xt 105 24 other other JJ cord-012719-5qa0e4xt 105 25 factors factor NNS cord-012719-5qa0e4xt 105 26 , , , cord-012719-5qa0e4xt 105 27 such such JJ cord-012719-5qa0e4xt 105 28 as as IN cord-012719-5qa0e4xt 105 29 insufficient insufficient JJ cord-012719-5qa0e4xt 105 30 blood blood NN cord-012719-5qa0e4xt 105 31 flow flow NN cord-012719-5qa0e4xt 105 32 to to IN cord-012719-5qa0e4xt 105 33 the the DT cord-012719-5qa0e4xt 105 34 ONH ONH NNP cord-012719-5qa0e4xt 105 35 and and CC cord-012719-5qa0e4xt 105 36 peripapillary peripapillary JJ cord-012719-5qa0e4xt 105 37 retina retina NN cord-012719-5qa0e4xt 105 38 [ [ -LRB- cord-012719-5qa0e4xt 105 39 22 22 CD cord-012719-5qa0e4xt 105 40 , , , cord-012719-5qa0e4xt 105 41 23 23 CD cord-012719-5qa0e4xt 105 42 ] ] -RRB- cord-012719-5qa0e4xt 105 43 . . . cord-012719-5qa0e4xt 106 1 In in IN cord-012719-5qa0e4xt 106 2 particular particular JJ cord-012719-5qa0e4xt 106 3 , , , cord-012719-5qa0e4xt 106 4 XFS XFS NNP cord-012719-5qa0e4xt 106 5 is be VBZ cord-012719-5qa0e4xt 106 6 greatly greatly RB cord-012719-5qa0e4xt 106 7 affected affect VBN cord-012719-5qa0e4xt 106 8 by by IN cord-012719-5qa0e4xt 106 9 genetic genetic JJ cord-012719-5qa0e4xt 106 10 and and CC cord-012719-5qa0e4xt 106 11 environmental environmental JJ cord-012719-5qa0e4xt 106 12 factors factor NNS cord-012719-5qa0e4xt 106 13 . . . cord-012719-5qa0e4xt 107 1 Many many JJ cord-012719-5qa0e4xt 107 2 epidemiological epidemiological JJ cord-012719-5qa0e4xt 107 3 studies study NNS cord-012719-5qa0e4xt 107 4 have have VBP cord-012719-5qa0e4xt 107 5 found find VBN cord-012719-5qa0e4xt 107 6 significant significant JJ cord-012719-5qa0e4xt 107 7 variability variability NN cord-012719-5qa0e4xt 107 8 in in IN cord-012719-5qa0e4xt 107 9 the the DT cord-012719-5qa0e4xt 107 10 prevalence prevalence NN cord-012719-5qa0e4xt 107 11 of of IN cord-012719-5qa0e4xt 107 12 XFS xfs NN cord-012719-5qa0e4xt 107 13 among among IN cord-012719-5qa0e4xt 107 14 different different JJ cord-012719-5qa0e4xt 107 15 ethnic ethnic JJ cord-012719-5qa0e4xt 107 16 groups group NNS cord-012719-5qa0e4xt 107 17 ( ( -LRB- cord-012719-5qa0e4xt 107 18 0.4 0.4 CD cord-012719-5qa0e4xt 107 19 - - SYM cord-012719-5qa0e4xt 107 20 18.1 18.1 CD cord-012719-5qa0e4xt 107 21 % % NN cord-012719-5qa0e4xt 107 22 ) ) -RRB- cord-012719-5qa0e4xt 107 23 [ [ -LRB- cord-012719-5qa0e4xt 107 24 24 24 CD cord-012719-5qa0e4xt 107 25 ] ] -RRB- cord-012719-5qa0e4xt 107 26 [ [ -LRB- cord-012719-5qa0e4xt 107 27 25 25 CD cord-012719-5qa0e4xt 107 28 ] ] -RRB- cord-012719-5qa0e4xt 107 29 [ [ -LRB- cord-012719-5qa0e4xt 107 30 26 26 CD cord-012719-5qa0e4xt 107 31 ] ] -RRB- cord-012719-5qa0e4xt 107 32 [ [ -LRB- cord-012719-5qa0e4xt 107 33 27 27 CD cord-012719-5qa0e4xt 107 34 ] ] -RRB- cord-012719-5qa0e4xt 107 35 . . . cord-012719-5qa0e4xt 108 1 Similarly similarly RB cord-012719-5qa0e4xt 108 2 , , , cord-012719-5qa0e4xt 108 3 the the DT cord-012719-5qa0e4xt 108 4 risk risk NN cord-012719-5qa0e4xt 108 5 allele allele NN cord-012719-5qa0e4xt 108 6 of of IN cord-012719-5qa0e4xt 108 7 LOXL1 LOXL1 NNP cord-012719-5qa0e4xt 108 8 rs1048661 rs1048661 NNP cord-012719-5qa0e4xt 108 9 is be VBZ cord-012719-5qa0e4xt 108 10 reversed reverse VBN cord-012719-5qa0e4xt 108 11 in in IN cord-012719-5qa0e4xt 108 12 the the DT cord-012719-5qa0e4xt 108 13 Asian asian JJ cord-012719-5qa0e4xt 108 14 ( ( -LRB- cord-012719-5qa0e4xt 108 15 Japanese Japanese NNPS cord-012719-5qa0e4xt 108 16 , , , cord-012719-5qa0e4xt 108 17 Chinese chinese JJ cord-012719-5qa0e4xt 108 18 , , , cord-012719-5qa0e4xt 108 19 and and CC cord-012719-5qa0e4xt 108 20 Korean korean JJ cord-012719-5qa0e4xt 108 21 ) ) -RRB- cord-012719-5qa0e4xt 108 22 population population NN cord-012719-5qa0e4xt 108 23 , , , cord-012719-5qa0e4xt 108 24 and and CC cord-012719-5qa0e4xt 108 25 rs1048661 rs1048661 NNP cord-012719-5qa0e4xt 108 26 is be VBZ cord-012719-5qa0e4xt 108 27 not not RB cord-012719-5qa0e4xt 108 28 associated associate VBN cord-012719-5qa0e4xt 108 29 with with IN cord-012719-5qa0e4xt 108 30 XFG XFG NNP cord-012719-5qa0e4xt 108 31 risk risk NN cord-012719-5qa0e4xt 108 32 in in IN cord-012719-5qa0e4xt 108 33 Greek Greek NNP cord-012719-5qa0e4xt 108 34 , , , cord-012719-5qa0e4xt 108 35 Indian indian JJ cord-012719-5qa0e4xt 108 36 , , , cord-012719-5qa0e4xt 108 37 Mexican Mexican NNP cord-012719-5qa0e4xt 108 38 , , , cord-012719-5qa0e4xt 108 39 and and CC cord-012719-5qa0e4xt 108 40 Polish polish JJ cord-012719-5qa0e4xt 108 41 populations population NNS cord-012719-5qa0e4xt 108 42 [ [ -LRB- cord-012719-5qa0e4xt 108 43 28 28 CD cord-012719-5qa0e4xt 108 44 ] ] -RRB- cord-012719-5qa0e4xt 108 45 . . . cord-012719-5qa0e4xt 109 1 Given give VBN cord-012719-5qa0e4xt 109 2 the the DT cord-012719-5qa0e4xt 109 3 conflicting conflict VBG cord-012719-5qa0e4xt 109 4 genetic genetic JJ cord-012719-5qa0e4xt 109 5 association association NN cord-012719-5qa0e4xt 109 6 results result NNS cord-012719-5qa0e4xt 109 7 and and CC cord-012719-5qa0e4xt 109 8 the the DT cord-012719-5qa0e4xt 109 9 variable variable JJ cord-012719-5qa0e4xt 109 10 prevalence prevalence NN cord-012719-5qa0e4xt 109 11 , , , cord-012719-5qa0e4xt 109 12 genetic genetic JJ cord-012719-5qa0e4xt 109 13 , , , cord-012719-5qa0e4xt 109 14 environmental environmental JJ cord-012719-5qa0e4xt 109 15 , , , cord-012719-5qa0e4xt 109 16 and and CC cord-012719-5qa0e4xt 109 17 racial racial JJ cord-012719-5qa0e4xt 109 18 differences difference NNS cord-012719-5qa0e4xt 109 19 should should MD cord-012719-5qa0e4xt 109 20 be be VB cord-012719-5qa0e4xt 109 21 kept keep VBN cord-012719-5qa0e4xt 109 22 in in IN cord-012719-5qa0e4xt 109 23 mind mind NN cord-012719-5qa0e4xt 109 24 . . . cord-012719-5qa0e4xt 110 1 To to IN cord-012719-5qa0e4xt 110 2 the the DT cord-012719-5qa0e4xt 110 3 best good JJS cord-012719-5qa0e4xt 110 4 of of IN cord-012719-5qa0e4xt 110 5 our -PRON- PRP$ cord-012719-5qa0e4xt 110 6 knowledge knowledge NN cord-012719-5qa0e4xt 110 7 , , , cord-012719-5qa0e4xt 110 8 the the DT cord-012719-5qa0e4xt 110 9 RNFL RNFL NNP cord-012719-5qa0e4xt 110 10 and and CC cord-012719-5qa0e4xt 110 11 GCC GCC NNP cord-012719-5qa0e4xt 110 12 thicknesses thickness NNS cord-012719-5qa0e4xt 110 13 have have VBP cord-012719-5qa0e4xt 110 14 not not RB cord-012719-5qa0e4xt 110 15 yet yet RB cord-012719-5qa0e4xt 110 16 been be VBN cord-012719-5qa0e4xt 110 17 compared compare VBN cord-012719-5qa0e4xt 110 18 between between IN cord-012719-5qa0e4xt 110 19 XFS xfs JJ cord-012719-5qa0e4xt 110 20 patients patient NNS cord-012719-5qa0e4xt 110 21 and and CC cord-012719-5qa0e4xt 110 22 controls control NNS cord-012719-5qa0e4xt 110 23 in in IN cord-012719-5qa0e4xt 110 24 an an DT cord-012719-5qa0e4xt 110 25 Asian asian JJ cord-012719-5qa0e4xt 110 26 population population NN cord-012719-5qa0e4xt 110 27 . . . cord-012719-5qa0e4xt 111 1 Our -PRON- PRP$ cord-012719-5qa0e4xt 111 2 results result NNS cord-012719-5qa0e4xt 111 3 raise raise VBP cord-012719-5qa0e4xt 111 4 the the DT cord-012719-5qa0e4xt 111 5 question question NN cord-012719-5qa0e4xt 111 6 about about IN cord-012719-5qa0e4xt 111 7 the the DT cord-012719-5qa0e4xt 111 8 reason reason NN cord-012719-5qa0e4xt 111 9 for for IN cord-012719-5qa0e4xt 111 10 thin thin JJ cord-012719-5qa0e4xt 111 11 RNFL RNFL NNP cord-012719-5qa0e4xt 111 12 and and CC cord-012719-5qa0e4xt 111 13 GCC GCC NNP cord-012719-5qa0e4xt 111 14 thickness thickness NN cord-012719-5qa0e4xt 111 15 in in IN cord-012719-5qa0e4xt 111 16 XFS xfs JJ cord-012719-5qa0e4xt 111 17 patients patient NNS cord-012719-5qa0e4xt 111 18 and and CC cord-012719-5qa0e4xt 111 19 the the DT cord-012719-5qa0e4xt 111 20 clinical clinical JJ cord-012719-5qa0e4xt 111 21 relevance relevance NN cord-012719-5qa0e4xt 111 22 of of IN cord-012719-5qa0e4xt 111 23 these these DT cord-012719-5qa0e4xt 111 24 changes change NNS cord-012719-5qa0e4xt 111 25 . . . cord-012719-5qa0e4xt 112 1 First first RB cord-012719-5qa0e4xt 112 2 of of IN cord-012719-5qa0e4xt 112 3 all all DT cord-012719-5qa0e4xt 112 4 , , , cord-012719-5qa0e4xt 112 5 the the DT cord-012719-5qa0e4xt 112 6 mean mean JJ cord-012719-5qa0e4xt 112 7 IOP IOP NNP cord-012719-5qa0e4xt 112 8 in in IN cord-012719-5qa0e4xt 112 9 XFS xfs NN cord-012719-5qa0e4xt 112 10 - - HYPH cord-012719-5qa0e4xt 112 11 affected affected JJ cord-012719-5qa0e4xt 112 12 and and CC cord-012719-5qa0e4xt 112 13 fellow fellow JJ cord-012719-5qa0e4xt 112 14 eyes eye NNS cord-012719-5qa0e4xt 112 15 appears appear VBZ cord-012719-5qa0e4xt 112 16 to to TO cord-012719-5qa0e4xt 112 17 be be VB cord-012719-5qa0e4xt 112 18 higher high JJR cord-012719-5qa0e4xt 112 19 than than IN cord-012719-5qa0e4xt 112 20 reported report VBN cord-012719-5qa0e4xt 112 21 by by IN cord-012719-5qa0e4xt 112 22 the the DT cord-012719-5qa0e4xt 112 23 Korean Korean NNP cord-012719-5qa0e4xt 112 24 National National NNP cord-012719-5qa0e4xt 112 25 Health Health NNP cord-012719-5qa0e4xt 112 26 and and CC cord-012719-5qa0e4xt 112 27 Nutrition Nutrition NNP cord-012719-5qa0e4xt 112 28 Survey Survey NNP cord-012719-5qa0e4xt 112 29 ( ( -LRB- cord-012719-5qa0e4xt 112 30 KNHANES KNHANES NNP cord-012719-5qa0e4xt 112 31 ) ) -RRB- cord-012719-5qa0e4xt 113 1 [ [ -LRB- cord-012719-5qa0e4xt 113 2 29 29 CD cord-012719-5qa0e4xt 113 3 ] ] -RRB- cord-012719-5qa0e4xt 113 4 ; ; : cord-012719-5qa0e4xt 113 5 it -PRON- PRP cord-012719-5qa0e4xt 113 6 was be VBD cord-012719-5qa0e4xt 113 7 13.7 13.7 CD cord-012719-5qa0e4xt 113 8 ± ± CD cord-012719-5qa0e4xt 113 9 2.8 2.8 CD cord-012719-5qa0e4xt 113 10 mmHg mmHg NNS cord-012719-5qa0e4xt 113 11 in in IN cord-012719-5qa0e4xt 113 12 those those DT cord-012719-5qa0e4xt 113 13 more more JJR cord-012719-5qa0e4xt 113 14 than than IN cord-012719-5qa0e4xt 113 15 70 70 CD cord-012719-5qa0e4xt 113 16 years year NNS cord-012719-5qa0e4xt 113 17 of of IN cord-012719-5qa0e4xt 113 18 age age NN cord-012719-5qa0e4xt 113 19 . . . cord-012719-5qa0e4xt 114 1 Therefore therefore RB cord-012719-5qa0e4xt 114 2 , , , cord-012719-5qa0e4xt 114 3 mean mean VB cord-012719-5qa0e4xt 114 4 IOP IOP NNP cord-012719-5qa0e4xt 114 5 of of IN cord-012719-5qa0e4xt 114 6 XFSaffected XFSaffected NNP cord-012719-5qa0e4xt 114 7 and and CC cord-012719-5qa0e4xt 114 8 fellow fellow JJ cord-012719-5qa0e4xt 114 9 eyes eye NNS cord-012719-5qa0e4xt 114 10 were be VBD cord-012719-5qa0e4xt 114 11 higher high JJR cord-012719-5qa0e4xt 114 12 than than IN cord-012719-5qa0e4xt 114 13 what what WP cord-012719-5qa0e4xt 114 14 was be VBD cord-012719-5qa0e4xt 114 15 seen see VBN cord-012719-5qa0e4xt 114 16 in in IN cord-012719-5qa0e4xt 114 17 that that DT cord-012719-5qa0e4xt 114 18 population population NN cord-012719-5qa0e4xt 114 19 ; ; : cord-012719-5qa0e4xt 114 20 this this DT cord-012719-5qa0e4xt 114 21 could could MD cord-012719-5qa0e4xt 114 22 be be VB cord-012719-5qa0e4xt 114 23 a a DT cord-012719-5qa0e4xt 114 24 reason reason NN cord-012719-5qa0e4xt 114 25 for for IN cord-012719-5qa0e4xt 114 26 the the DT cord-012719-5qa0e4xt 114 27 RNFL RNFL NNP cord-012719-5qa0e4xt 114 28 loss loss NN cord-012719-5qa0e4xt 114 29 . . . cord-012719-5qa0e4xt 115 1 Besides besides IN cord-012719-5qa0e4xt 115 2 the the DT cord-012719-5qa0e4xt 115 3 impact impact NN cord-012719-5qa0e4xt 115 4 of of IN cord-012719-5qa0e4xt 115 5 IOP IOP NNP cord-012719-5qa0e4xt 115 6 , , , cord-012719-5qa0e4xt 115 7 we -PRON- PRP cord-012719-5qa0e4xt 115 8 postulate postulate VBP cord-012719-5qa0e4xt 115 9 that that IN cord-012719-5qa0e4xt 115 10 the the DT cord-012719-5qa0e4xt 115 11 reasons reason NNS cord-012719-5qa0e4xt 115 12 for for IN cord-012719-5qa0e4xt 115 13 the the DT cord-012719-5qa0e4xt 115 14 thin thin JJ cord-012719-5qa0e4xt 115 15 RNFL RNFL NNP cord-012719-5qa0e4xt 115 16 and and CC cord-012719-5qa0e4xt 115 17 GCC GCC NNP cord-012719-5qa0e4xt 115 18 thickness thickness NN cord-012719-5qa0e4xt 115 19 in in IN cord-012719-5qa0e4xt 115 20 the the DT cord-012719-5qa0e4xt 115 21 present present JJ cord-012719-5qa0e4xt 115 22 study study NN cord-012719-5qa0e4xt 115 23 are be VBP cord-012719-5qa0e4xt 115 24 related relate VBN cord-012719-5qa0e4xt 115 25 to to IN cord-012719-5qa0e4xt 115 26 ( ( -LRB- cord-012719-5qa0e4xt 115 27 1 1 CD cord-012719-5qa0e4xt 115 28 ) ) -RRB- cord-012719-5qa0e4xt 115 29 systemic systemic JJ cord-012719-5qa0e4xt 115 30 , , , cord-012719-5qa0e4xt 115 31 or or CC cord-012719-5qa0e4xt 115 32 ( ( -LRB- cord-012719-5qa0e4xt 115 33 2 2 LS cord-012719-5qa0e4xt 115 34 ) ) -RRB- cord-012719-5qa0e4xt 115 35 local local JJ cord-012719-5qa0e4xt 115 36 vascular vascular JJ cord-012719-5qa0e4xt 115 37 factors factor NNS cord-012719-5qa0e4xt 115 38 , , , cord-012719-5qa0e4xt 115 39 and and CC cord-012719-5qa0e4xt 115 40 Data datum NNS cord-012719-5qa0e4xt 115 41 are be VBP cord-012719-5qa0e4xt 115 42 presented present VBN cord-012719-5qa0e4xt 115 43 as as IN cord-012719-5qa0e4xt 115 44 mean mean JJ cord-012719-5qa0e4xt 115 45 ± ± NNP cord-012719-5qa0e4xt 115 46 SD SD NNP cord-012719-5qa0e4xt 115 47 ( ( -LRB- cord-012719-5qa0e4xt 115 48 range range NN cord-012719-5qa0e4xt 115 49 ) ) -RRB- cord-012719-5qa0e4xt 115 50 ; ; : cord-012719-5qa0e4xt 115 51 P p NN cord-012719-5qa0e4xt 115 52 value value NN cord-012719-5qa0e4xt 115 53 was be VBD cord-012719-5qa0e4xt 115 54 calculated calculate VBN cord-012719-5qa0e4xt 115 55 by by IN cord-012719-5qa0e4xt 115 56 one one CD cord-012719-5qa0e4xt 115 57 - - HYPH cord-012719-5qa0e4xt 115 58 way way NN cord-012719-5qa0e4xt 115 59 ANOVA ANOVA NNP cord-012719-5qa0e4xt 115 60 ANOVA ANOVA NNP cord-012719-5qa0e4xt 115 61 analysis analysis NN cord-012719-5qa0e4xt 115 62 of of IN cord-012719-5qa0e4xt 115 63 variance variance NN cord-012719-5qa0e4xt 115 64 , , , cord-012719-5qa0e4xt 115 65 RNFL RNFL NNP cord-012719-5qa0e4xt 115 66 retinal retinal JJ cord-012719-5qa0e4xt 115 67 nerve nerve NN cord-012719-5qa0e4xt 115 68 fiber fiber NN cord-012719-5qa0e4xt 115 69 layer layer NN cord-012719-5qa0e4xt 115 70 , , , cord-012719-5qa0e4xt 116 1 XFS XFS NNP cord-012719-5qa0e4xt 116 2 exfoliation exfoliation NN cord-012719-5qa0e4xt 116 3 syndrome syndrome NN cord-012719-5qa0e4xt 116 4 a a NN cord-012719-5qa0e4xt 117 1 Although although IN cord-012719-5qa0e4xt 117 2 the the DT cord-012719-5qa0e4xt 117 3 p p NN cord-012719-5qa0e4xt 117 4 value value NN cord-012719-5qa0e4xt 117 5 by by IN cord-012719-5qa0e4xt 117 6 ANOVA ANOVA NNP cord-012719-5qa0e4xt 117 7 demonstrated demonstrate VBD cord-012719-5qa0e4xt 117 8 statistical statistical JJ cord-012719-5qa0e4xt 117 9 borderline borderline JJ cord-012719-5qa0e4xt 117 10 significance significance NN cord-012719-5qa0e4xt 117 11 , , , cord-012719-5qa0e4xt 117 12 post post JJ cord-012719-5qa0e4xt 117 13 - - JJ cord-012719-5qa0e4xt 117 14 hoc hoc JJ cord-012719-5qa0e4xt 117 15 analysis analysis NN cord-012719-5qa0e4xt 117 16 was be VBD cord-012719-5qa0e4xt 117 17 performed perform VBN cord-012719-5qa0e4xt 117 18 using use VBG cord-012719-5qa0e4xt 117 19 Tukey Tukey NNP cord-012719-5qa0e4xt 117 20 's 's POS cord-012719-5qa0e4xt 117 21 test test NN cord-012719-5qa0e4xt 117 22 . . . cord-012719-5qa0e4xt 118 1 The the DT cord-012719-5qa0e4xt 118 2 P p NN cord-012719-5qa0e4xt 118 3 value value NN cord-012719-5qa0e4xt 118 4 for for IN cord-012719-5qa0e4xt 118 5 comparison comparison NN cord-012719-5qa0e4xt 118 6 of of IN cord-012719-5qa0e4xt 118 7 XFS xfs NN cord-012719-5qa0e4xt 118 8 - - HYPH cord-012719-5qa0e4xt 118 9 affected affect VBN cord-012719-5qa0e4xt 118 10 eyes eye NNS cord-012719-5qa0e4xt 118 11 and and CC cord-012719-5qa0e4xt 118 12 fellow fellow JJ cord-012719-5qa0e4xt 118 13 eyes eye NNS cord-012719-5qa0e4xt 119 1 ( ( -LRB- cord-012719-5qa0e4xt 119 2 P1 P1 NNP cord-012719-5qa0e4xt 119 3 ) ) -RRB- cord-012719-5qa0e4xt 119 4 was be VBD cord-012719-5qa0e4xt 119 5 0.739 0.739 CD cord-012719-5qa0e4xt 119 6 ; ; : cord-012719-5qa0e4xt 119 7 the the DT cord-012719-5qa0e4xt 119 8 P p NN cord-012719-5qa0e4xt 119 9 value value NN cord-012719-5qa0e4xt 119 10 for for IN cord-012719-5qa0e4xt 119 11 comparison comparison NN cord-012719-5qa0e4xt 119 12 of of IN cord-012719-5qa0e4xt 119 13 XFS xfs NN cord-012719-5qa0e4xt 119 14 - - HYPH cord-012719-5qa0e4xt 119 15 affected affect VBN cord-012719-5qa0e4xt 119 16 eyes eye NNS cord-012719-5qa0e4xt 119 17 and and CC cord-012719-5qa0e4xt 119 18 control control NN cord-012719-5qa0e4xt 119 19 ( ( -LRB- cord-012719-5qa0e4xt 119 20 P2 p2 NN cord-012719-5qa0e4xt 119 21 ) ) -RRB- cord-012719-5qa0e4xt 119 22 eyes eye NNS cord-012719-5qa0e4xt 119 23 was be VBD cord-012719-5qa0e4xt 119 24 0.014 0.014 CD cord-012719-5qa0e4xt 119 25 ; ; : cord-012719-5qa0e4xt 119 26 and and CC cord-012719-5qa0e4xt 119 27 the the DT cord-012719-5qa0e4xt 119 28 P p NN cord-012719-5qa0e4xt 119 29 value value NN cord-012719-5qa0e4xt 119 30 for for IN cord-012719-5qa0e4xt 119 31 comparison comparison NN cord-012719-5qa0e4xt 119 32 of of IN cord-012719-5qa0e4xt 119 33 fellow fellow JJ cord-012719-5qa0e4xt 119 34 eyes eye NNS cord-012719-5qa0e4xt 119 35 and and CC cord-012719-5qa0e4xt 119 36 control control NN cord-012719-5qa0e4xt 119 37 eyes eye NNS cord-012719-5qa0e4xt 120 1 ( ( -LRB- cord-012719-5qa0e4xt 120 2 P3 P3 NNP cord-012719-5qa0e4xt 120 3 ) ) -RRB- cord-012719-5qa0e4xt 120 4 was be VBD cord-012719-5qa0e4xt 120 5 0.151 0.151 CD cord-012719-5qa0e4xt 120 6 b b LS cord-012719-5qa0e4xt 120 7 Post Post NNP cord-012719-5qa0e4xt 120 8 - - JJ cord-012719-5qa0e4xt 120 9 hoc hoc JJ cord-012719-5qa0e4xt 120 10 analysis analysis NN cord-012719-5qa0e4xt 120 11 was be VBD cord-012719-5qa0e4xt 120 12 performed perform VBN cord-012719-5qa0e4xt 120 13 using use VBG cord-012719-5qa0e4xt 120 14 Tukey Tukey NNP cord-012719-5qa0e4xt 120 15 's 's POS cord-012719-5qa0e4xt 120 16 method method NN cord-012719-5qa0e4xt 120 17 : : : cord-012719-5qa0e4xt 120 18 P1 p1 NN cord-012719-5qa0e4xt 120 19 = = SYM cord-012719-5qa0e4xt 120 20 0.607 0.607 NFP cord-012719-5qa0e4xt 120 21 ; ; : cord-012719-5qa0e4xt 120 22 P2 p2 NN cord-012719-5qa0e4xt 120 23 = = SYM cord-012719-5qa0e4xt 120 24 0.001 0.001 CD cord-012719-5qa0e4xt 120 25 , , , cord-012719-5qa0e4xt 120 26 and and CC cord-012719-5qa0e4xt 120 27 P3 p3 NN cord-012719-5qa0e4xt 120 28 = = SYM cord-012719-5qa0e4xt 120 29 0.033 0.033 CD cord-012719-5qa0e4xt 120 30 [ [ -LRB- cord-012719-5qa0e4xt 120 31 9 9 CD cord-012719-5qa0e4xt 120 32 , , , cord-012719-5qa0e4xt 120 33 11 11 CD cord-012719-5qa0e4xt 120 34 ] ] -RRB- cord-012719-5qa0e4xt 120 35 . . . cord-012719-5qa0e4xt 121 1 These these DT cord-012719-5qa0e4xt 121 2 retinal retinal JJ cord-012719-5qa0e4xt 121 3 ischemia ischemia NN cord-012719-5qa0e4xt 121 4 can can MD cord-012719-5qa0e4xt 121 5 lead lead VB cord-012719-5qa0e4xt 121 6 to to IN cord-012719-5qa0e4xt 121 7 ganglion ganglion NN cord-012719-5qa0e4xt 121 8 cell cell NN cord-012719-5qa0e4xt 121 9 death death NN cord-012719-5qa0e4xt 121 10 and and CC cord-012719-5qa0e4xt 121 11 ONH ONH NNP cord-012719-5qa0e4xt 121 12 atrophy atrophy NN cord-012719-5qa0e4xt 121 13 [ [ -LRB- cord-012719-5qa0e4xt 121 14 30 30 CD cord-012719-5qa0e4xt 121 15 ] ] -RRB- cord-012719-5qa0e4xt 121 16 , , , cord-012719-5qa0e4xt 121 17 and and CC cord-012719-5qa0e4xt 121 18 it -PRON- PRP cord-012719-5qa0e4xt 121 19 has have VBZ cord-012719-5qa0e4xt 121 20 been be VBN cord-012719-5qa0e4xt 121 21 suggested suggest VBN cord-012719-5qa0e4xt 121 22 that that IN cord-012719-5qa0e4xt 121 23 diminished diminish VBD cord-012719-5qa0e4xt 121 24 ocular ocular JJ cord-012719-5qa0e4xt 121 25 blood blood NN cord-012719-5qa0e4xt 121 26 flow flow NN cord-012719-5qa0e4xt 121 27 contributes contribute VBZ cord-012719-5qa0e4xt 121 28 to to IN cord-012719-5qa0e4xt 121 29 the the DT cord-012719-5qa0e4xt 121 30 development development NN cord-012719-5qa0e4xt 121 31 of of IN cord-012719-5qa0e4xt 121 32 RNFL RNFL NNP cord-012719-5qa0e4xt 121 33 damage damage NN cord-012719-5qa0e4xt 121 34 in in IN cord-012719-5qa0e4xt 121 35 XFS xfs JJ cord-012719-5qa0e4xt 121 36 patients patient NNS cord-012719-5qa0e4xt 121 37 . . . cord-012719-5qa0e4xt 122 1 Second second JJ cord-012719-5qa0e4xt 122 2 , , , cord-012719-5qa0e4xt 122 3 local local JJ cord-012719-5qa0e4xt 122 4 vascular vascular JJ cord-012719-5qa0e4xt 122 5 factors factor NNS cord-012719-5qa0e4xt 122 6 should should MD cord-012719-5qa0e4xt 122 7 also also RB cord-012719-5qa0e4xt 122 8 be be VB cord-012719-5qa0e4xt 122 9 considered consider VBN cord-012719-5qa0e4xt 122 10 . . . cord-012719-5qa0e4xt 123 1 XFM XFM NNP cord-012719-5qa0e4xt 123 2 accumulation accumulation NN cord-012719-5qa0e4xt 123 3 in in IN cord-012719-5qa0e4xt 123 4 short short JJ cord-012719-5qa0e4xt 123 5 posterior posterior JJ cord-012719-5qa0e4xt 123 6 ciliary ciliary NN cord-012719-5qa0e4xt 123 7 arteries artery NNS cord-012719-5qa0e4xt 123 8 , , , cord-012719-5qa0e4xt 123 9 central central JJ cord-012719-5qa0e4xt 123 10 retinal retinal JJ cord-012719-5qa0e4xt 123 11 vessels vessel NNS cord-012719-5qa0e4xt 123 12 , , , cord-012719-5qa0e4xt 123 13 the the DT cord-012719-5qa0e4xt 123 14 optic optic JJ cord-012719-5qa0e4xt 123 15 nerve nerve NN cord-012719-5qa0e4xt 123 16 sheath sheath NN cord-012719-5qa0e4xt 123 17 , , , cord-012719-5qa0e4xt 123 18 and and CC cord-012719-5qa0e4xt 123 19 vortex vortex NN cord-012719-5qa0e4xt 123 20 veins vein NNS cord-012719-5qa0e4xt 123 21 could could MD cord-012719-5qa0e4xt 123 22 cause cause VB cord-012719-5qa0e4xt 123 23 vascular vascular JJ cord-012719-5qa0e4xt 123 24 alterations alteration NNS cord-012719-5qa0e4xt 123 25 , , , cord-012719-5qa0e4xt 123 26 ischemic ischemic JJ cord-012719-5qa0e4xt 123 27 changes change NNS cord-012719-5qa0e4xt 123 28 and and CC cord-012719-5qa0e4xt 123 29 subsequent subsequent JJ cord-012719-5qa0e4xt 123 30 RNFL RNFL NNP cord-012719-5qa0e4xt 123 31 and and CC cord-012719-5qa0e4xt 123 32 GCC gcc NN cord-012719-5qa0e4xt 123 33 thinning thin VBG cord-012719-5qa0e4xt 123 34 [ [ -LRB- cord-012719-5qa0e4xt 123 35 21 21 CD cord-012719-5qa0e4xt 123 36 ] ] -RRB- cord-012719-5qa0e4xt 123 37 . . . cord-012719-5qa0e4xt 124 1 Ocakoglu Ocakoglu NNP cord-012719-5qa0e4xt 124 2 et et NNP cord-012719-5qa0e4xt 124 3 al al NNP cord-012719-5qa0e4xt 124 4 . . . cord-012719-5qa0e4xt 125 1 [ [ -LRB- cord-012719-5qa0e4xt 125 2 31 31 CD cord-012719-5qa0e4xt 125 3 ] ] -RRB- cord-012719-5qa0e4xt 125 4 reported report VBD cord-012719-5qa0e4xt 125 5 that that IN cord-012719-5qa0e4xt 125 6 microvascular microvascular JJ cord-012719-5qa0e4xt 125 7 blood blood NN cord-012719-5qa0e4xt 125 8 flow flow NN cord-012719-5qa0e4xt 125 9 in in IN cord-012719-5qa0e4xt 125 10 the the DT cord-012719-5qa0e4xt 125 11 optic optic JJ cord-012719-5qa0e4xt 125 12 nerve nerve NN cord-012719-5qa0e4xt 125 13 and and CC cord-012719-5qa0e4xt 125 14 peripapillary peripapillary JJ cord-012719-5qa0e4xt 125 15 retina retina NN cord-012719-5qa0e4xt 125 16 was be VBD cord-012719-5qa0e4xt 125 17 decreased decrease VBN cord-012719-5qa0e4xt 125 18 , , , cord-012719-5qa0e4xt 125 19 based base VBN cord-012719-5qa0e4xt 125 20 on on IN cord-012719-5qa0e4xt 125 21 Heidelberg Heidelberg NNP cord-012719-5qa0e4xt 125 22 retinal retinal JJ cord-012719-5qa0e4xt 125 23 flowmeter flowmeter NN cord-012719-5qa0e4xt 125 24 measurements measurement NNS cord-012719-5qa0e4xt 125 25 . . . cord-012719-5qa0e4xt 126 1 Their -PRON- PRP$ cord-012719-5qa0e4xt 126 2 study study NN cord-012719-5qa0e4xt 126 3 supported support VBD cord-012719-5qa0e4xt 126 4 our -PRON- PRP$ cord-012719-5qa0e4xt 126 5 hypothesis hypothesis NN cord-012719-5qa0e4xt 126 6 . . . cord-012719-5qa0e4xt 127 1 Besides besides IN cord-012719-5qa0e4xt 127 2 compromised compromised JJ cord-012719-5qa0e4xt 127 3 vasculature vasculature NN cord-012719-5qa0e4xt 127 4 , , , cord-012719-5qa0e4xt 127 5 the the DT cord-012719-5qa0e4xt 127 6 effect effect NN cord-012719-5qa0e4xt 127 7 of of IN cord-012719-5qa0e4xt 127 8 mechanical mechanical JJ cord-012719-5qa0e4xt 127 9 changes change NNS cord-012719-5qa0e4xt 127 10 of of IN cord-012719-5qa0e4xt 127 11 the the DT cord-012719-5qa0e4xt 127 12 ONH ONH NNP cord-012719-5qa0e4xt 127 13 should should MD cord-012719-5qa0e4xt 127 14 be be VB cord-012719-5qa0e4xt 127 15 considered consider VBN cord-012719-5qa0e4xt 127 16 . . . cord-012719-5qa0e4xt 128 1 A a DT cord-012719-5qa0e4xt 128 2 thin thin JJ cord-012719-5qa0e4xt 128 3 lamina lamina JJ cord-012719-5qa0e4xt 128 4 cribrosa cribrosa NN cord-012719-5qa0e4xt 128 5 of of IN cord-012719-5qa0e4xt 128 6 XFS XFS NNP cord-012719-5qa0e4xt 128 7 was be VBD cord-012719-5qa0e4xt 128 8 reported report VBN cord-012719-5qa0e4xt 128 9 by by IN cord-012719-5qa0e4xt 128 10 some some DT cord-012719-5qa0e4xt 128 11 studies study NNS cord-012719-5qa0e4xt 128 12 [ [ -LRB- cord-012719-5qa0e4xt 128 13 32 32 CD cord-012719-5qa0e4xt 128 14 , , , cord-012719-5qa0e4xt 128 15 33 33 CD cord-012719-5qa0e4xt 128 16 ] ] -RRB- cord-012719-5qa0e4xt 128 17 . . . cord-012719-5qa0e4xt 129 1 The the DT cord-012719-5qa0e4xt 129 2 decreased decreased JJ cord-012719-5qa0e4xt 129 3 stiffness stiffness NN cord-012719-5qa0e4xt 129 4 of of IN cord-012719-5qa0e4xt 129 5 the the DT cord-012719-5qa0e4xt 129 6 lamina lamina NNP cord-012719-5qa0e4xt 129 7 cribrosa cribrosa NNP cord-012719-5qa0e4xt 129 8 and and CC cord-012719-5qa0e4xt 129 9 peripapillary peripapillary JJ cord-012719-5qa0e4xt 129 10 scleral scleral JJ cord-012719-5qa0e4xt 129 11 tissues tissue NNS cord-012719-5qa0e4xt 129 12 caused cause VBN cord-012719-5qa0e4xt 129 13 by by IN cord-012719-5qa0e4xt 129 14 XFS XFS NNP cord-012719-5qa0e4xt 129 15 may may MD cord-012719-5qa0e4xt 129 16 reflect reflect VB cord-012719-5qa0e4xt 129 17 an an DT cord-012719-5qa0e4xt 129 18 inherent inherent JJ cord-012719-5qa0e4xt 129 19 tissue tissue NN cord-012719-5qa0e4xt 129 20 weakness weakness NN cord-012719-5qa0e4xt 129 21 , , , cord-012719-5qa0e4xt 129 22 especially especially RB cord-012719-5qa0e4xt 129 23 in in IN cord-012719-5qa0e4xt 129 24 older old JJR cord-012719-5qa0e4xt 129 25 patients patient NNS cord-012719-5qa0e4xt 129 26 [ [ -LRB- cord-012719-5qa0e4xt 129 27 34 34 CD cord-012719-5qa0e4xt 129 28 ] ] -RRB- cord-012719-5qa0e4xt 129 29 . . . cord-012719-5qa0e4xt 130 1 This this DT cord-012719-5qa0e4xt 130 2 may may MD cord-012719-5qa0e4xt 130 3 in in IN cord-012719-5qa0e4xt 130 4 turn turn NN cord-012719-5qa0e4xt 130 5 render render VB cord-012719-5qa0e4xt 130 6 these these DT cord-012719-5qa0e4xt 130 7 eyes eye NNS cord-012719-5qa0e4xt 130 8 more more RBR cord-012719-5qa0e4xt 130 9 vulnerable vulnerable JJ cord-012719-5qa0e4xt 130 10 to to IN cord-012719-5qa0e4xt 130 11 IOP IOP NNP cord-012719-5qa0e4xt 130 12 fluctuations fluctuation NNS cord-012719-5qa0e4xt 130 13 and and CC cord-012719-5qa0e4xt 130 14 optic optic JJ cord-012719-5qa0e4xt 130 15 nerve nerve NN cord-012719-5qa0e4xt 130 16 damage damage NN cord-012719-5qa0e4xt 130 17 . . . cord-012719-5qa0e4xt 131 1 In in IN cord-012719-5qa0e4xt 131 2 addition addition NN cord-012719-5qa0e4xt 131 3 , , , cord-012719-5qa0e4xt 131 4 Jonas Jonas NNP cord-012719-5qa0e4xt 131 5 [ [ -LRB- cord-012719-5qa0e4xt 131 6 35 35 CD cord-012719-5qa0e4xt 131 7 ] ] -RRB- cord-012719-5qa0e4xt 131 8 reported report VBD cord-012719-5qa0e4xt 131 9 that that IN cord-012719-5qa0e4xt 131 10 the the DT cord-012719-5qa0e4xt 131 11 obstruction obstruction NN cord-012719-5qa0e4xt 131 12 of of IN cord-012719-5qa0e4xt 131 13 the the DT cord-012719-5qa0e4xt 131 14 venous venous JJ cord-012719-5qa0e4xt 131 15 outflow outflow NN cord-012719-5qa0e4xt 131 16 system system NN cord-012719-5qa0e4xt 131 17 could could MD cord-012719-5qa0e4xt 131 18 be be VB cord-012719-5qa0e4xt 131 19 caused cause VBN cord-012719-5qa0e4xt 131 20 by by IN cord-012719-5qa0e4xt 131 21 mechanical mechanical JJ cord-012719-5qa0e4xt 131 22 distortion distortion NN cord-012719-5qa0e4xt 131 23 of of IN cord-012719-5qa0e4xt 131 24 the the DT cord-012719-5qa0e4xt 131 25 lamina lamina NNP cord-012719-5qa0e4xt 131 26 cribrosa cribrosa NNP cord-012719-5qa0e4xt 131 27 . . . cord-012719-5qa0e4xt 132 1 Structural structural JJ cord-012719-5qa0e4xt 132 2 alterations alteration NNS cord-012719-5qa0e4xt 132 3 of of IN cord-012719-5qa0e4xt 132 4 the the DT cord-012719-5qa0e4xt 132 5 lamina lamina NNP cord-012719-5qa0e4xt 132 6 cribrosa cribrosa NNP cord-012719-5qa0e4xt 132 7 may may MD cord-012719-5qa0e4xt 132 8 also also RB cord-012719-5qa0e4xt 132 9 influence influence VB cord-012719-5qa0e4xt 132 10 hemodynamic hemodynamic JJ cord-012719-5qa0e4xt 132 11 changes change NNS cord-012719-5qa0e4xt 132 12 , , , cord-012719-5qa0e4xt 132 13 such such JJ cord-012719-5qa0e4xt 132 14 as as IN cord-012719-5qa0e4xt 132 15 increased increase VBN cord-012719-5qa0e4xt 132 16 venous venous JJ cord-012719-5qa0e4xt 132 17 outflow outflow NN cord-012719-5qa0e4xt 132 18 resistance resistance NN cord-012719-5qa0e4xt 132 19 or or CC cord-012719-5qa0e4xt 132 20 turbulence turbulence NN cord-012719-5qa0e4xt 132 21 . . . cord-012719-5qa0e4xt 133 1 In in IN cord-012719-5qa0e4xt 133 2 this this DT cord-012719-5qa0e4xt 133 3 study study NN cord-012719-5qa0e4xt 133 4 , , , cord-012719-5qa0e4xt 133 5 thin thin JJ cord-012719-5qa0e4xt 133 6 RNFL RNFL NNP cord-012719-5qa0e4xt 133 7 and and CC cord-012719-5qa0e4xt 133 8 GCC GCC NNP cord-012719-5qa0e4xt 133 9 thicknesses thickness NNS cord-012719-5qa0e4xt 133 10 were be VBD cord-012719-5qa0e4xt 133 11 also also RB cord-012719-5qa0e4xt 133 12 observed observe VBN cord-012719-5qa0e4xt 133 13 in in IN cord-012719-5qa0e4xt 133 14 the the DT cord-012719-5qa0e4xt 133 15 fellow fellow JJ cord-012719-5qa0e4xt 133 16 eyes eye NNS cord-012719-5qa0e4xt 133 17 of of IN cord-012719-5qa0e4xt 133 18 patients patient NNS cord-012719-5qa0e4xt 133 19 with with IN cord-012719-5qa0e4xt 133 20 unilateral unilateral JJ cord-012719-5qa0e4xt 133 21 XFS xfs NN cord-012719-5qa0e4xt 133 22 , , , cord-012719-5qa0e4xt 133 23 as as IN cord-012719-5qa0e4xt 133 24 compared compare VBN cord-012719-5qa0e4xt 133 25 with with IN cord-012719-5qa0e4xt 133 26 that that DT cord-012719-5qa0e4xt 133 27 of of IN cord-012719-5qa0e4xt 133 28 healthy healthy JJ cord-012719-5qa0e4xt 133 29 control control NN cord-012719-5qa0e4xt 133 30 subjects subject NNS cord-012719-5qa0e4xt 133 31 . . . cord-012719-5qa0e4xt 134 1 These these DT cord-012719-5qa0e4xt 134 2 findings finding NNS cord-012719-5qa0e4xt 134 3 suggest suggest VBP cord-012719-5qa0e4xt 134 4 that that IN cord-012719-5qa0e4xt 134 5 both both DT cord-012719-5qa0e4xt 134 6 eyes eye NNS cord-012719-5qa0e4xt 134 7 of of IN cord-012719-5qa0e4xt 134 8 patients patient NNS cord-012719-5qa0e4xt 134 9 with with IN cord-012719-5qa0e4xt 134 10 unilateral unilateral JJ cord-012719-5qa0e4xt 134 11 XFS xfs NN cord-012719-5qa0e4xt 134 12 could could MD cord-012719-5qa0e4xt 134 13 have have VB cord-012719-5qa0e4xt 134 14 structural structural JJ cord-012719-5qa0e4xt 134 15 changes change NNS cord-012719-5qa0e4xt 134 16 or or CC cord-012719-5qa0e4xt 134 17 vulnerability vulnerability NN cord-012719-5qa0e4xt 134 18 to to IN cord-012719-5qa0e4xt 134 19 the the DT cord-012719-5qa0e4xt 134 20 development development NN cord-012719-5qa0e4xt 134 21 of of IN cord-012719-5qa0e4xt 134 22 glaucoma glaucoma NN cord-012719-5qa0e4xt 134 23 , , , cord-012719-5qa0e4xt 134 24 considering consider VBG cord-012719-5qa0e4xt 134 25 that that IN cord-012719-5qa0e4xt 134 26 the the DT cord-012719-5qa0e4xt 134 27 RNFL RNFL NNP cord-012719-5qa0e4xt 134 28 and and CC cord-012719-5qa0e4xt 134 29 GCC GCC NNP cord-012719-5qa0e4xt 134 30 thicknesses thickness NNS cord-012719-5qa0e4xt 134 31 were be VBD cord-012719-5qa0e4xt 134 32 found find VBN cord-012719-5qa0e4xt 134 33 to to TO cord-012719-5qa0e4xt 134 34 be be VB cord-012719-5qa0e4xt 134 35 thinner thin JJR cord-012719-5qa0e4xt 134 36 in in IN cord-012719-5qa0e4xt 134 37 glaucoma glaucoma NN cord-012719-5qa0e4xt 134 38 patients patient NNS cord-012719-5qa0e4xt 134 39 than than IN cord-012719-5qa0e4xt 134 40 in in IN cord-012719-5qa0e4xt 134 41 healthy healthy JJ cord-012719-5qa0e4xt 134 42 control control NN cord-012719-5qa0e4xt 134 43 subjects subject NNS cord-012719-5qa0e4xt 134 44 in in IN cord-012719-5qa0e4xt 134 45 previous previous JJ cord-012719-5qa0e4xt 134 46 studies study NNS cord-012719-5qa0e4xt 134 47 [ [ -LRB- cord-012719-5qa0e4xt 134 48 12 12 CD cord-012719-5qa0e4xt 134 49 , , , cord-012719-5qa0e4xt 134 50 15 15 CD cord-012719-5qa0e4xt 134 51 ] ] -RRB- cord-012719-5qa0e4xt 134 52 . . . cord-012719-5qa0e4xt 135 1 In in IN cord-012719-5qa0e4xt 135 2 particular particular JJ cord-012719-5qa0e4xt 135 3 , , , cord-012719-5qa0e4xt 135 4 XFS XFS NNP cord-012719-5qa0e4xt 135 5 is be VBZ cord-012719-5qa0e4xt 135 6 considered consider VBN cord-012719-5qa0e4xt 135 7 an an DT cord-012719-5qa0e4xt 135 8 asymmetric asymmetric JJ cord-012719-5qa0e4xt 135 9 bilateral bilateral JJ cord-012719-5qa0e4xt 135 10 disease disease NN cord-012719-5qa0e4xt 135 11 . . . cord-012719-5qa0e4xt 136 1 XFS xfs VB cord-012719-5qa0e4xt 136 2 often often RB cord-012719-5qa0e4xt 136 3 occurs occur VBZ cord-012719-5qa0e4xt 136 4 unilaterally unilaterally RB cord-012719-5qa0e4xt 136 5 , , , cord-012719-5qa0e4xt 136 6 but but CC cord-012719-5qa0e4xt 136 7 within within IN cord-012719-5qa0e4xt 136 8 5 5 CD cord-012719-5qa0e4xt 136 9 years year NNS cord-012719-5qa0e4xt 136 10 , , , cord-012719-5qa0e4xt 136 11 14 14 CD cord-012719-5qa0e4xt 136 12 - - SYM cord-012719-5qa0e4xt 136 13 41 41 CD cord-012719-5qa0e4xt 136 14 % % NN cord-012719-5qa0e4xt 136 15 of of IN cord-012719-5qa0e4xt 136 16 cases case NNS cord-012719-5qa0e4xt 136 17 may may MD cord-012719-5qa0e4xt 136 18 convert convert VB cord-012719-5qa0e4xt 136 19 to to IN cord-012719-5qa0e4xt 136 20 the the DT cord-012719-5qa0e4xt 136 21 bilateral bilateral JJ cord-012719-5qa0e4xt 136 22 form form NN cord-012719-5qa0e4xt 136 23 [ [ -LRB- cord-012719-5qa0e4xt 136 24 36 36 CD cord-012719-5qa0e4xt 136 25 , , , cord-012719-5qa0e4xt 136 26 37 37 CD cord-012719-5qa0e4xt 136 27 ] ] -RRB- cord-012719-5qa0e4xt 136 28 . . . cord-012719-5qa0e4xt 137 1 Iris Iris NNP cord-012719-5qa0e4xt 137 2 vasculopathies vasculopathie NNS cord-012719-5qa0e4xt 137 3 are be VBP cord-012719-5qa0e4xt 137 4 also also RB cord-012719-5qa0e4xt 137 5 detected detect VBN cord-012719-5qa0e4xt 137 6 in in IN cord-012719-5qa0e4xt 137 7 both both DT cord-012719-5qa0e4xt 137 8 eyes eye NNS cord-012719-5qa0e4xt 137 9 of of IN cord-012719-5qa0e4xt 137 10 patients patient NNS cord-012719-5qa0e4xt 137 11 with with IN cord-012719-5qa0e4xt 137 12 unilateral unilateral JJ cord-012719-5qa0e4xt 137 13 XFS xfs NN cord-012719-5qa0e4xt 137 14 [ [ -LRB- cord-012719-5qa0e4xt 137 15 38 38 CD cord-012719-5qa0e4xt 137 16 ] ] -RRB- cord-012719-5qa0e4xt 137 17 . . . cord-012719-5qa0e4xt 138 1 In in IN cord-012719-5qa0e4xt 138 2 this this DT cord-012719-5qa0e4xt 138 3 context context NN cord-012719-5qa0e4xt 138 4 , , , cord-012719-5qa0e4xt 138 5 our -PRON- PRP$ cord-012719-5qa0e4xt 138 6 study study NN cord-012719-5qa0e4xt 138 7 shows show VBZ cord-012719-5qa0e4xt 138 8 thin thin JJ cord-012719-5qa0e4xt 138 9 RNFL RNFL NNP cord-012719-5qa0e4xt 138 10 and and CC cord-012719-5qa0e4xt 138 11 GCC GCC NNP cord-012719-5qa0e4xt 138 12 thicknesses thickness NNS cord-012719-5qa0e4xt 138 13 in in IN cord-012719-5qa0e4xt 138 14 both both DT cord-012719-5qa0e4xt 138 15 eyes eye NNS cord-012719-5qa0e4xt 138 16 of of IN cord-012719-5qa0e4xt 138 17 patients patient NNS cord-012719-5qa0e4xt 138 18 with with IN cord-012719-5qa0e4xt 138 19 unilateral unilateral JJ cord-012719-5qa0e4xt 138 20 XFS xfs NN cord-012719-5qa0e4xt 138 21 . . . cord-012719-5qa0e4xt 139 1 Our -PRON- PRP$ cord-012719-5qa0e4xt 139 2 study study NN cord-012719-5qa0e4xt 139 3 had have VBD cord-012719-5qa0e4xt 139 4 some some DT cord-012719-5qa0e4xt 139 5 limitations limitation NNS cord-012719-5qa0e4xt 139 6 . . . cord-012719-5qa0e4xt 140 1 First first RB cord-012719-5qa0e4xt 140 2 , , , cord-012719-5qa0e4xt 140 3 the the DT cord-012719-5qa0e4xt 140 4 sample sample NN cord-012719-5qa0e4xt 140 5 sizes size NNS cord-012719-5qa0e4xt 140 6 were be VBD cord-012719-5qa0e4xt 140 7 relatively relatively RB cord-012719-5qa0e4xt 140 8 small small JJ cord-012719-5qa0e4xt 140 9 ; ; : cord-012719-5qa0e4xt 140 10 this this DT cord-012719-5qa0e4xt 140 11 was be VBD cord-012719-5qa0e4xt 140 12 especially especially RB cord-012719-5qa0e4xt 140 13 apparent apparent JJ cord-012719-5qa0e4xt 140 14 in in IN cord-012719-5qa0e4xt 140 15 our -PRON- PRP$ cord-012719-5qa0e4xt 140 16 subgroup subgroup NN cord-012719-5qa0e4xt 140 17 analysis analysis NN cord-012719-5qa0e4xt 140 18 . . . cord-012719-5qa0e4xt 141 1 Second second RB cord-012719-5qa0e4xt 141 2 , , , cord-012719-5qa0e4xt 141 3 blood blood NN cord-012719-5qa0e4xt 141 4 pressure pressure NN cord-012719-5qa0e4xt 141 5 and and CC cord-012719-5qa0e4xt 141 6 diurnal diurnal JJ cord-012719-5qa0e4xt 141 7 IOP IOP NNP cord-012719-5qa0e4xt 141 8 fluctuations fluctuation NNS cord-012719-5qa0e4xt 141 9 were be VBD cord-012719-5qa0e4xt 141 10 not not RB cord-012719-5qa0e4xt 141 11 considered consider VBN cord-012719-5qa0e4xt 141 12 in in IN cord-012719-5qa0e4xt 141 13 this this DT cord-012719-5qa0e4xt 141 14 study study NN cord-012719-5qa0e4xt 141 15 . . . cord-012719-5qa0e4xt 142 1 However however RB cord-012719-5qa0e4xt 142 2 , , , cord-012719-5qa0e4xt 142 3 all all DT cord-012719-5qa0e4xt 142 4 patients patient NNS cord-012719-5qa0e4xt 142 5 were be VBD cord-012719-5qa0e4xt 142 6 enrolled enrol VBN cord-012719-5qa0e4xt 142 7 at at IN cord-012719-5qa0e4xt 142 8 a a DT cord-012719-5qa0e4xt 142 9 similar similar JJ cord-012719-5qa0e4xt 142 10 time time NN cord-012719-5qa0e4xt 142 11 of of IN cord-012719-5qa0e4xt 142 12 the the DT cord-012719-5qa0e4xt 142 13 morning morning NN cord-012719-5qa0e4xt 142 14 , , , cord-012719-5qa0e4xt 142 15 minimizing minimize VBG cord-012719-5qa0e4xt 142 16 the the DT cord-012719-5qa0e4xt 142 17 effect effect NN cord-012719-5qa0e4xt 142 18 of of IN cord-012719-5qa0e4xt 142 19 diurnal diurnal JJ cord-012719-5qa0e4xt 142 20 variation variation NN cord-012719-5qa0e4xt 142 21 . . . cord-012719-5qa0e4xt 143 1 Third third RB cord-012719-5qa0e4xt 143 2 , , , cord-012719-5qa0e4xt 143 3 a a DT cord-012719-5qa0e4xt 143 4 total total NN cord-012719-5qa0e4xt 143 5 of of IN cord-012719-5qa0e4xt 143 6 28 28 CD cord-012719-5qa0e4xt 143 7 pseudophakic pseudophakic NN cord-012719-5qa0e4xt 143 8 eyes eye NNS cord-012719-5qa0e4xt 143 9 were be VBD cord-012719-5qa0e4xt 143 10 included include VBN cord-012719-5qa0e4xt 143 11 because because IN cord-012719-5qa0e4xt 143 12 elderly elderly JJ cord-012719-5qa0e4xt 143 13 patients patient NNS cord-012719-5qa0e4xt 143 14 were be VBD cord-012719-5qa0e4xt 143 15 enrolled enrol VBN cord-012719-5qa0e4xt 143 16 in in IN cord-012719-5qa0e4xt 143 17 our -PRON- PRP$ cord-012719-5qa0e4xt 143 18 study study NN cord-012719-5qa0e4xt 143 19 . . . cord-012719-5qa0e4xt 144 1 IOP IOP NNP cord-012719-5qa0e4xt 144 2 could could MD cord-012719-5qa0e4xt 144 3 be be VB cord-012719-5qa0e4xt 144 4 influenced influence VBN cord-012719-5qa0e4xt 144 5 by by IN cord-012719-5qa0e4xt 144 6 pseudophakia pseudophakia NN cord-012719-5qa0e4xt 144 7 , , , cord-012719-5qa0e4xt 144 8 but but CC cord-012719-5qa0e4xt 144 9 there there EX cord-012719-5qa0e4xt 144 10 was be VBD cord-012719-5qa0e4xt 144 11 no no DT cord-012719-5qa0e4xt 144 12 significant significant JJ cord-012719-5qa0e4xt 144 13 difference difference NN cord-012719-5qa0e4xt 144 14 between between IN cord-012719-5qa0e4xt 144 15 groups group NNS cord-012719-5qa0e4xt 144 16 in in IN cord-012719-5qa0e4xt 144 17 terms term NNS cord-012719-5qa0e4xt 144 18 of of IN cord-012719-5qa0e4xt 144 19 lens lens NN cord-012719-5qa0e4xt 144 20 status status NN cord-012719-5qa0e4xt 144 21 . . . cord-012719-5qa0e4xt 145 1 Fourth fourth RB cord-012719-5qa0e4xt 145 2 , , , cord-012719-5qa0e4xt 145 3 we -PRON- PRP cord-012719-5qa0e4xt 145 4 could could MD cord-012719-5qa0e4xt 145 5 not not RB cord-012719-5qa0e4xt 145 6 exclude exclude VB cord-012719-5qa0e4xt 145 7 the the DT cord-012719-5qa0e4xt 145 8 effect effect NN cord-012719-5qa0e4xt 145 9 of of IN cord-012719-5qa0e4xt 145 10 IOP IOP NNP cord-012719-5qa0e4xt 145 11 on on IN cord-012719-5qa0e4xt 145 12 RNFL RNFL NNP cord-012719-5qa0e4xt 145 13 and and CC cord-012719-5qa0e4xt 145 14 GCC GCC NNP cord-012719-5qa0e4xt 145 15 thickness thickness NN cord-012719-5qa0e4xt 145 16 . . . cord-012719-5qa0e4xt 146 1 The the DT cord-012719-5qa0e4xt 146 2 mean mean JJ cord-012719-5qa0e4xt 146 3 IOP IOP NNP cord-012719-5qa0e4xt 146 4 of of IN cord-012719-5qa0e4xt 146 5 XFS XFS NNP cord-012719-5qa0e4xt 146 6 patients patient NNS cord-012719-5qa0e4xt 146 7 was be VBD cord-012719-5qa0e4xt 146 8 slightly slightly RB cord-012719-5qa0e4xt 146 9 higher high JJR cord-012719-5qa0e4xt 146 10 than than IN cord-012719-5qa0e4xt 146 11 that that DT cord-012719-5qa0e4xt 146 12 of of IN cord-012719-5qa0e4xt 146 13 controls control NNS cord-012719-5qa0e4xt 146 14 . . . cord-012719-5qa0e4xt 147 1 However however RB cord-012719-5qa0e4xt 147 2 , , , cord-012719-5qa0e4xt 147 3 the the DT cord-012719-5qa0e4xt 147 4 mean mean JJ cord-012719-5qa0e4xt 147 5 IOP IOP NNP cord-012719-5qa0e4xt 147 6 and and CC cord-012719-5qa0e4xt 147 7 IOP IOP NNP cord-012719-5qa0e4xt 147 8 fluctuation fluctuation NN cord-012719-5qa0e4xt 147 9 of of IN cord-012719-5qa0e4xt 147 10 the the DT cord-012719-5qa0e4xt 147 11 XFS xfs NN cord-012719-5qa0e4xt 147 12 patients patient NNS cord-012719-5qa0e4xt 147 13 were be VBD cord-012719-5qa0e4xt 147 14 higher high JJR cord-012719-5qa0e4xt 147 15 than than IN cord-012719-5qa0e4xt 147 16 controls control NNS cord-012719-5qa0e4xt 147 17 levels level NNS cord-012719-5qa0e4xt 147 18 in in IN cord-012719-5qa0e4xt 147 19 other other JJ cord-012719-5qa0e4xt 147 20 studies study NNS cord-012719-5qa0e4xt 147 21 [ [ -LRB- cord-012719-5qa0e4xt 147 22 39 39 CD cord-012719-5qa0e4xt 147 23 , , , cord-012719-5qa0e4xt 147 24 40 40 CD cord-012719-5qa0e4xt 147 25 ] ] -RRB- cord-012719-5qa0e4xt 147 26 . . . cord-012719-5qa0e4xt 148 1 These these DT cord-012719-5qa0e4xt 148 2 results result NNS cord-012719-5qa0e4xt 148 3 are be VBP cord-012719-5qa0e4xt 148 4 compatible compatible JJ cord-012719-5qa0e4xt 148 5 with with IN cord-012719-5qa0e4xt 148 6 those those DT cord-012719-5qa0e4xt 148 7 of of IN cord-012719-5qa0e4xt 148 8 other other JJ cord-012719-5qa0e4xt 148 9 studies study NNS cord-012719-5qa0e4xt 148 10 [ [ -LRB- cord-012719-5qa0e4xt 148 11 12 12 CD cord-012719-5qa0e4xt 148 12 ] ] -RRB- cord-012719-5qa0e4xt 148 13 . . . cord-012719-5qa0e4xt 149 1 In in IN cord-012719-5qa0e4xt 149 2 addition addition NN cord-012719-5qa0e4xt 149 3 , , , cord-012719-5qa0e4xt 149 4 the the DT cord-012719-5qa0e4xt 149 5 difference difference NN cord-012719-5qa0e4xt 149 6 in in IN cord-012719-5qa0e4xt 149 7 IOP IOP NNP cord-012719-5qa0e4xt 149 8 was be VBD cord-012719-5qa0e4xt 149 9 only only RB cord-012719-5qa0e4xt 149 10 about about RB cord-012719-5qa0e4xt 149 11 2.7 2.7 CD cord-012719-5qa0e4xt 149 12 mmHg mmHg NNS cord-012719-5qa0e4xt 149 13 in in IN cord-012719-5qa0e4xt 149 14 our -PRON- PRP$ cord-012719-5qa0e4xt 149 15 study study NN cord-012719-5qa0e4xt 149 16 ; ; : cord-012719-5qa0e4xt 149 17 thus thus RB cord-012719-5qa0e4xt 149 18 , , , cord-012719-5qa0e4xt 149 19 IOP IOP NNP cord-012719-5qa0e4xt 149 20 might may MD cord-012719-5qa0e4xt 149 21 not not RB cord-012719-5qa0e4xt 149 22 affect affect VB cord-012719-5qa0e4xt 149 23 the the DT cord-012719-5qa0e4xt 149 24 thickness thickness NN cord-012719-5qa0e4xt 149 25 of of IN cord-012719-5qa0e4xt 149 26 GCC GCC NNP cord-012719-5qa0e4xt 149 27 and and CC cord-012719-5qa0e4xt 149 28 RNFL RNFL NNP cord-012719-5qa0e4xt 149 29 markedly markedly RB cord-012719-5qa0e4xt 149 30 . . . cord-012719-5qa0e4xt 150 1 In in IN cord-012719-5qa0e4xt 150 2 conclusion conclusion NN cord-012719-5qa0e4xt 150 3 , , , cord-012719-5qa0e4xt 150 4 RNFL RNFL NNP cord-012719-5qa0e4xt 150 5 and and CC cord-012719-5qa0e4xt 150 6 GCC GCC NNP cord-012719-5qa0e4xt 150 7 thicknesses thickness NNS cord-012719-5qa0e4xt 150 8 were be VBD cord-012719-5qa0e4xt 150 9 significantly significantly RB cord-012719-5qa0e4xt 150 10 thinner thin JJR cord-012719-5qa0e4xt 150 11 in in IN cord-012719-5qa0e4xt 150 12 Asian asian JJ cord-012719-5qa0e4xt 150 13 patients patient NNS cord-012719-5qa0e4xt 150 14 with with IN cord-012719-5qa0e4xt 150 15 XFS XFS NNP cord-012719-5qa0e4xt 150 16 without without IN cord-012719-5qa0e4xt 150 17 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 150 18 damage damage NN cord-012719-5qa0e4xt 150 19 compared compare VBN cord-012719-5qa0e4xt 150 20 with with IN cord-012719-5qa0e4xt 150 21 healthy healthy JJ cord-012719-5qa0e4xt 150 22 controls control NNS cord-012719-5qa0e4xt 150 23 . . . cord-012719-5qa0e4xt 151 1 Systemic systemic JJ cord-012719-5qa0e4xt 151 2 or or CC cord-012719-5qa0e4xt 151 3 local local JJ cord-012719-5qa0e4xt 151 4 vascular vascular JJ cord-012719-5qa0e4xt 151 5 changes change NNS cord-012719-5qa0e4xt 151 6 and and CC cord-012719-5qa0e4xt 151 7 mechanical mechanical JJ cord-012719-5qa0e4xt 151 8 alterations alteration NNS cord-012719-5qa0e4xt 151 9 could could MD cord-012719-5qa0e4xt 151 10 play play VB cord-012719-5qa0e4xt 151 11 a a DT cord-012719-5qa0e4xt 151 12 role role NN cord-012719-5qa0e4xt 151 13 . . . cord-012719-5qa0e4xt 152 1 Thus thus RB cord-012719-5qa0e4xt 152 2 , , , cord-012719-5qa0e4xt 152 3 physicians physician NNS cord-012719-5qa0e4xt 152 4 should should MD cord-012719-5qa0e4xt 152 5 consider consider VB cord-012719-5qa0e4xt 152 6 that that DT cord-012719-5qa0e4xt 152 7 diagnosis diagnosis NN cord-012719-5qa0e4xt 152 8 of of IN cord-012719-5qa0e4xt 152 9 XFS XFS NNP cord-012719-5qa0e4xt 152 10 itself -PRON- PRP cord-012719-5qa0e4xt 152 11 might may MD cord-012719-5qa0e4xt 152 12 predict predict VB cord-012719-5qa0e4xt 152 13 a a DT cord-012719-5qa0e4xt 152 14 thin thin JJ cord-012719-5qa0e4xt 152 15 retinal retinal JJ cord-012719-5qa0e4xt 152 16 change change NN cord-012719-5qa0e4xt 152 17 and and CC cord-012719-5qa0e4xt 152 18 may may MD cord-012719-5qa0e4xt 152 19 be be VB cord-012719-5qa0e4xt 152 20 a a DT cord-012719-5qa0e4xt 152 21 risk risk NN cord-012719-5qa0e4xt 152 22 factor factor NN cord-012719-5qa0e4xt 152 23 for for IN cord-012719-5qa0e4xt 152 24 development development NN cord-012719-5qa0e4xt 152 25 of of IN cord-012719-5qa0e4xt 152 26 a a DT cord-012719-5qa0e4xt 152 27 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 152 28 optic optic JJ cord-012719-5qa0e4xt 152 29 disc disc NN cord-012719-5qa0e4xt 152 30 and and CC cord-012719-5qa0e4xt 152 31 RNFL RNFL NNP cord-012719-5qa0e4xt 152 32 damage damage NN cord-012719-5qa0e4xt 152 33 . . . cord-012719-5qa0e4xt 153 1 What what WP cord-012719-5qa0e4xt 153 2 was be VBD cord-012719-5qa0e4xt 153 3 known know VBN cord-012719-5qa0e4xt 153 4 before before IN cord-012719-5qa0e4xt 153 5 _SP cord-012719-5qa0e4xt 154 1 Why why WRB cord-012719-5qa0e4xt 154 2 is be VBZ cord-012719-5qa0e4xt 154 3 glaucoma glaucoma NN cord-012719-5qa0e4xt 154 4 associated associate VBN cord-012719-5qa0e4xt 154 5 with with IN cord-012719-5qa0e4xt 154 6 exfoliation exfoliation NN cord-012719-5qa0e4xt 154 7 syndrome syndrome NN cord-012719-5qa0e4xt 154 8 ? ? . cord-012719-5qa0e4xt 155 1 Exfoliation exfoliation NN cord-012719-5qa0e4xt 155 2 syndrome syndrome NN cord-012719-5qa0e4xt 156 1 A a DT cord-012719-5qa0e4xt 156 2 possible possible JJ cord-012719-5qa0e4xt 156 3 link link NN cord-012719-5qa0e4xt 156 4 between between IN cord-012719-5qa0e4xt 156 5 the the DT cord-012719-5qa0e4xt 156 6 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 156 7 syndrome syndrome NN cord-012719-5qa0e4xt 156 8 and and CC cord-012719-5qa0e4xt 156 9 coronary coronary JJ cord-012719-5qa0e4xt 156 10 artery artery NN cord-012719-5qa0e4xt 156 11 disease disease NN cord-012719-5qa0e4xt 156 12 Exfoliation Exfoliation NNP cord-012719-5qa0e4xt 156 13 syndrome syndrome NN cord-012719-5qa0e4xt 156 14 and and CC cord-012719-5qa0e4xt 156 15 systemic systemic JJ cord-012719-5qa0e4xt 156 16 cardiovascular cardiovascular JJ cord-012719-5qa0e4xt 156 17 diseases disease NNS cord-012719-5qa0e4xt 156 18 Ocular ocular JJ cord-012719-5qa0e4xt 156 19 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 156 20 syndrome syndrome NN cord-012719-5qa0e4xt 156 21 and and CC cord-012719-5qa0e4xt 156 22 vascular vascular JJ cord-012719-5qa0e4xt 156 23 disease disease NN cord-012719-5qa0e4xt 156 24 : : : cord-012719-5qa0e4xt 156 25 a a DT cord-012719-5qa0e4xt 156 26 systematic systematic JJ cord-012719-5qa0e4xt 156 27 review review NN cord-012719-5qa0e4xt 156 28 and and CC cord-012719-5qa0e4xt 156 29 metaanalysis metaanalysis NN cord-012719-5qa0e4xt 156 30 Early early JJ cord-012719-5qa0e4xt 156 31 changes change NNS cord-012719-5qa0e4xt 156 32 in in IN cord-012719-5qa0e4xt 156 33 iris iris JJ cord-012719-5qa0e4xt 156 34 blood blood NN cord-012719-5qa0e4xt 156 35 vessels vessel NNS cord-012719-5qa0e4xt 156 36 in in IN cord-012719-5qa0e4xt 156 37 exfoliation exfoliation NN cord-012719-5qa0e4xt 156 38 syndrome syndrome NN cord-012719-5qa0e4xt 156 39 Retinal retinal JJ cord-012719-5qa0e4xt 156 40 vascular vascular JJ cord-012719-5qa0e4xt 156 41 occlusions occlusion NNS cord-012719-5qa0e4xt 156 42 occur occur VBP cord-012719-5qa0e4xt 156 43 more more RBR cord-012719-5qa0e4xt 156 44 frequently frequently RB cord-012719-5qa0e4xt 156 45 in in IN cord-012719-5qa0e4xt 156 46 the the DT cord-012719-5qa0e4xt 156 47 more more RBR cord-012719-5qa0e4xt 156 48 affected affected JJ cord-012719-5qa0e4xt 156 49 eye eye NN cord-012719-5qa0e4xt 156 50 in in IN cord-012719-5qa0e4xt 156 51 exfoliation exfoliation NN cord-012719-5qa0e4xt 156 52 syndrome syndrome NN cord-012719-5qa0e4xt 156 53 Color color NN cord-012719-5qa0e4xt 156 54 Doppler Doppler NNP cord-012719-5qa0e4xt 156 55 imaging imaging NN cord-012719-5qa0e4xt 156 56 of of IN cord-012719-5qa0e4xt 156 57 the the DT cord-012719-5qa0e4xt 156 58 ophthalmic ophthalmic JJ cord-012719-5qa0e4xt 156 59 artery artery NN cord-012719-5qa0e4xt 156 60 blood blood NN cord-012719-5qa0e4xt 156 61 flow flow NN cord-012719-5qa0e4xt 156 62 spectra spectrum NNS cord-012719-5qa0e4xt 156 63 of of IN cord-012719-5qa0e4xt 156 64 patients patient NNS cord-012719-5qa0e4xt 156 65 who who WP cord-012719-5qa0e4xt 156 66 have have VBP cord-012719-5qa0e4xt 156 67 had have VBN cord-012719-5qa0e4xt 156 68 a a DT cord-012719-5qa0e4xt 156 69 transient transient JJ cord-012719-5qa0e4xt 156 70 ischemic ischemic JJ cord-012719-5qa0e4xt 156 71 attack attack NN cord-012719-5qa0e4xt 156 72 : : : cord-012719-5qa0e4xt 156 73 correlations correlation NNS cord-012719-5qa0e4xt 156 74 with with IN cord-012719-5qa0e4xt 156 75 generalized generalized JJ cord-012719-5qa0e4xt 156 76 iris iris NNP cord-012719-5qa0e4xt 156 77 transluminance transluminance NN cord-012719-5qa0e4xt 156 78 and and CC cord-012719-5qa0e4xt 156 79 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 156 80 syndrome syndrome NN cord-012719-5qa0e4xt 156 81 Ocular ocular JJ cord-012719-5qa0e4xt 156 82 hemodynamics hemodynamic NNS cord-012719-5qa0e4xt 156 83 in in IN cord-012719-5qa0e4xt 156 84 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 156 85 syndrome syndrome NN cord-012719-5qa0e4xt 156 86 and and CC cord-012719-5qa0e4xt 157 1 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 157 2 glaucoma glaucoma NNP cord-012719-5qa0e4xt 157 3 Monolateral Monolateral NNP cord-012719-5qa0e4xt 157 4 pseudoexfoliatio pseudoexfoliatio NNP cord-012719-5qa0e4xt 157 5 capsulae capsulae NNP cord-012719-5qa0e4xt 157 6 : : : cord-012719-5qa0e4xt 158 1 a a DT cord-012719-5qa0e4xt 158 2 study study NN cord-012719-5qa0e4xt 158 3 of of IN cord-012719-5qa0e4xt 158 4 choroidal choroidal JJ cord-012719-5qa0e4xt 158 5 blood blood NN cord-012719-5qa0e4xt 158 6 flow flow NN cord-012719-5qa0e4xt 158 7 Homocysteine Homocysteine NNP cord-012719-5qa0e4xt 158 8 and and CC cord-012719-5qa0e4xt 158 9 nitric nitric NN cord-012719-5qa0e4xt 158 10 oxide oxide NN cord-012719-5qa0e4xt 158 11 levels level NNS cord-012719-5qa0e4xt 158 12 in in IN cord-012719-5qa0e4xt 158 13 plasma plasma NN cord-012719-5qa0e4xt 158 14 of of IN cord-012719-5qa0e4xt 158 15 patients patient NNS cord-012719-5qa0e4xt 158 16 with with IN cord-012719-5qa0e4xt 158 17 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 158 18 syndrome syndrome NN cord-012719-5qa0e4xt 158 19 , , , cord-012719-5qa0e4xt 158 20 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 158 21 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 22 , , , cord-012719-5qa0e4xt 158 23 and and CC cord-012719-5qa0e4xt 158 24 primary primary JJ cord-012719-5qa0e4xt 158 25 open open JJ cord-012719-5qa0e4xt 158 26 - - HYPH cord-012719-5qa0e4xt 158 27 angle angle NN cord-012719-5qa0e4xt 158 28 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 29 Evaluation Evaluation NNP cord-012719-5qa0e4xt 158 30 of of IN cord-012719-5qa0e4xt 158 31 retinal retinal JJ cord-012719-5qa0e4xt 158 32 nerve nerve NN cord-012719-5qa0e4xt 158 33 fiber fiber NN cord-012719-5qa0e4xt 158 34 layer layer NN cord-012719-5qa0e4xt 158 35 and and CC cord-012719-5qa0e4xt 158 36 ganglion ganglion NN cord-012719-5qa0e4xt 158 37 cell cell NN cord-012719-5qa0e4xt 158 38 complex complex JJ cord-012719-5qa0e4xt 158 39 thickness thickness NN cord-012719-5qa0e4xt 158 40 in in IN cord-012719-5qa0e4xt 158 41 unilateral unilateral JJ cord-012719-5qa0e4xt 158 42 exfoliation exfoliation NN cord-012719-5qa0e4xt 158 43 syndrome syndrome NN cord-012719-5qa0e4xt 158 44 using use VBG cord-012719-5qa0e4xt 158 45 optical optical JJ cord-012719-5qa0e4xt 158 46 coherence coherence NN cord-012719-5qa0e4xt 158 47 tomography tomography NN cord-012719-5qa0e4xt 158 48 Baseline baseline JJ cord-012719-5qa0e4xt 158 49 optical optical JJ cord-012719-5qa0e4xt 158 50 coherence coherence NN cord-012719-5qa0e4xt 158 51 tomography tomography NN cord-012719-5qa0e4xt 158 52 predicts predict VBZ cord-012719-5qa0e4xt 158 53 the the DT cord-012719-5qa0e4xt 158 54 development development NN cord-012719-5qa0e4xt 158 55 of of IN cord-012719-5qa0e4xt 158 56 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 158 57 change change NN cord-012719-5qa0e4xt 158 58 in in IN cord-012719-5qa0e4xt 158 59 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 60 suspects suspect NNS cord-012719-5qa0e4xt 158 61 Topography Topography NNP cord-012719-5qa0e4xt 158 62 of of IN cord-012719-5qa0e4xt 158 63 ganglion ganglion NN cord-012719-5qa0e4xt 158 64 cells cell NNS cord-012719-5qa0e4xt 158 65 in in IN cord-012719-5qa0e4xt 158 66 human human JJ cord-012719-5qa0e4xt 158 67 retina retina NN cord-012719-5qa0e4xt 158 68 Structural structural JJ cord-012719-5qa0e4xt 158 69 changes change NNS cord-012719-5qa0e4xt 158 70 in in IN cord-012719-5qa0e4xt 158 71 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 158 72 syndrome syndrome NN cord-012719-5qa0e4xt 158 73 evaluated evaluate VBN cord-012719-5qa0e4xt 158 74 with with IN cord-012719-5qa0e4xt 158 75 spectral spectral JJ cord-012719-5qa0e4xt 158 76 domain domain NN cord-012719-5qa0e4xt 158 77 optical optical JJ cord-012719-5qa0e4xt 158 78 coherence coherence NN cord-012719-5qa0e4xt 158 79 tomography tomography NN cord-012719-5qa0e4xt 158 80 Static static JJ cord-012719-5qa0e4xt 158 81 threshold threshold NN cord-012719-5qa0e4xt 158 82 asymmetry asymmetry NN cord-012719-5qa0e4xt 158 83 in in IN cord-012719-5qa0e4xt 158 84 early early JJ cord-012719-5qa0e4xt 158 85 glaucomatous glaucomatous JJ cord-012719-5qa0e4xt 158 86 visual visual JJ cord-012719-5qa0e4xt 158 87 field field NN cord-012719-5qa0e4xt 158 88 loss loss NN cord-012719-5qa0e4xt 158 89 Macular Macular NNP cord-012719-5qa0e4xt 158 90 and and CC cord-012719-5qa0e4xt 158 91 peripapillary peripapillary JJ cord-012719-5qa0e4xt 158 92 retinal retinal JJ cord-012719-5qa0e4xt 158 93 nerve nerve NN cord-012719-5qa0e4xt 158 94 fiber fiber NN cord-012719-5qa0e4xt 158 95 layer layer NN cord-012719-5qa0e4xt 158 96 measurements measurement NNS cord-012719-5qa0e4xt 158 97 by by IN cord-012719-5qa0e4xt 158 98 spectral spectral JJ cord-012719-5qa0e4xt 158 99 domain domain NN cord-012719-5qa0e4xt 158 100 optical optical JJ cord-012719-5qa0e4xt 158 101 coherence coherence NN cord-012719-5qa0e4xt 158 102 tomography tomography NN cord-012719-5qa0e4xt 158 103 in in IN cord-012719-5qa0e4xt 158 104 normaltension normaltension NN cord-012719-5qa0e4xt 158 105 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 106 Retinal retinal JJ cord-012719-5qa0e4xt 158 107 nerve nerve NN cord-012719-5qa0e4xt 158 108 fiber fiber NN cord-012719-5qa0e4xt 158 109 layer layer NN cord-012719-5qa0e4xt 158 110 thickness thickness NN cord-012719-5qa0e4xt 158 111 changes change NNS cord-012719-5qa0e4xt 158 112 in in IN cord-012719-5qa0e4xt 158 113 the the DT cord-012719-5qa0e4xt 158 114 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 158 115 syndrome syndrome NN cord-012719-5qa0e4xt 158 116 : : : cord-012719-5qa0e4xt 158 117 a a DT cord-012719-5qa0e4xt 158 118 meta meta JJ cord-012719-5qa0e4xt 158 119 - - HYPH cord-012719-5qa0e4xt 158 120 analysis analysis NN cord-012719-5qa0e4xt 158 121 of of IN cord-012719-5qa0e4xt 158 122 case case NN cord-012719-5qa0e4xt 158 123 - - HYPH cord-012719-5qa0e4xt 158 124 control control NN cord-012719-5qa0e4xt 158 125 studies study NNS cord-012719-5qa0e4xt 158 126 Macula Macula NNP cord-012719-5qa0e4xt 158 127 vessel vessel NN cord-012719-5qa0e4xt 158 128 density density NN cord-012719-5qa0e4xt 158 129 and and CC cord-012719-5qa0e4xt 158 130 foveal foveal JJ cord-012719-5qa0e4xt 158 131 avascular avascular JJ cord-012719-5qa0e4xt 158 132 zone zone NN cord-012719-5qa0e4xt 158 133 parameters parameter NNS cord-012719-5qa0e4xt 158 134 in in IN cord-012719-5qa0e4xt 158 135 exfoliation exfoliation NN cord-012719-5qa0e4xt 158 136 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 137 compared compare VBN cord-012719-5qa0e4xt 158 138 to to IN cord-012719-5qa0e4xt 158 139 primary primary JJ cord-012719-5qa0e4xt 158 140 open open JJ cord-012719-5qa0e4xt 158 141 - - HYPH cord-012719-5qa0e4xt 158 142 angle angle NN cord-012719-5qa0e4xt 158 143 glaucoma glaucoma NN cord-012719-5qa0e4xt 158 144 Comparison comparison NN cord-012719-5qa0e4xt 158 145 of of IN cord-012719-5qa0e4xt 158 146 retinal retinal JJ cord-012719-5qa0e4xt 158 147 nerve nerve NN cord-012719-5qa0e4xt 158 148 fiber fiber NN cord-012719-5qa0e4xt 158 149 layer layer NN cord-012719-5qa0e4xt 158 150 thickness thickness NN cord-012719-5qa0e4xt 158 151 in in IN cord-012719-5qa0e4xt 158 152 patients patient NNS cord-012719-5qa0e4xt 158 153 having have VBG cord-012719-5qa0e4xt 158 154 pseudo pseudo JJ cord-012719-5qa0e4xt 158 155 exfoliation exfoliation NN cord-012719-5qa0e4xt 158 156 syndrome syndrome NN cord-012719-5qa0e4xt 158 157 with with IN cord-012719-5qa0e4xt 158 158 healthy healthy JJ cord-012719-5qa0e4xt 158 159 adults adult NNS cord-012719-5qa0e4xt 158 160 Analysis Analysis NNP cord-012719-5qa0e4xt 158 161 of of IN cord-012719-5qa0e4xt 158 162 retinal retinal JJ cord-012719-5qa0e4xt 158 163 nerve nerve NN cord-012719-5qa0e4xt 158 164 fiber fiber NN cord-012719-5qa0e4xt 158 165 layer layer NN cord-012719-5qa0e4xt 158 166 thickness thickness NN cord-012719-5qa0e4xt 158 167 in in IN cord-012719-5qa0e4xt 158 168 patients patient NNS cord-012719-5qa0e4xt 158 169 with with IN cord-012719-5qa0e4xt 158 170 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 158 171 syndrome syndrome NN cord-012719-5qa0e4xt 158 172 using use VBG cord-012719-5qa0e4xt 158 173 optical optical JJ cord-012719-5qa0e4xt 158 174 coherence coherence NN cord-012719-5qa0e4xt 158 175 tomography tomography NN cord-012719-5qa0e4xt 158 176 . . . cord-012719-5qa0e4xt 159 1 Ophthalmologica Ophthalmologica NNP cord-012719-5qa0e4xt 159 2 Hemodynamic Hemodynamic NNP cord-012719-5qa0e4xt 159 3 evaluation evaluation NN cord-012719-5qa0e4xt 159 4 of of IN cord-012719-5qa0e4xt 159 5 the the DT cord-012719-5qa0e4xt 159 6 posterior posterior JJ cord-012719-5qa0e4xt 159 7 ciliary ciliary NN cord-012719-5qa0e4xt 159 8 circulation circulation NN cord-012719-5qa0e4xt 159 9 in in IN cord-012719-5qa0e4xt 159 10 exfoliation exfoliation NN cord-012719-5qa0e4xt 159 11 syndrome syndrome NN cord-012719-5qa0e4xt 159 12 and and CC cord-012719-5qa0e4xt 159 13 exfoliation exfoliation NN cord-012719-5qa0e4xt 159 14 glaucoma glaucoma NN cord-012719-5qa0e4xt 159 15 Orbital orbital JJ cord-012719-5qa0e4xt 159 16 blood blood NN cord-012719-5qa0e4xt 159 17 flow flow NN cord-012719-5qa0e4xt 159 18 parameters parameter NNS cord-012719-5qa0e4xt 159 19 in in IN cord-012719-5qa0e4xt 159 20 unilateral unilateral JJ cord-012719-5qa0e4xt 159 21 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 159 22 syndrome syndrome NN cord-012719-5qa0e4xt 159 23 Epidemiology Epidemiology NNP cord-012719-5qa0e4xt 159 24 of of IN cord-012719-5qa0e4xt 159 25 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 159 26 in in IN cord-012719-5qa0e4xt 159 27 the the DT cord-012719-5qa0e4xt 159 28 island island NN cord-012719-5qa0e4xt 159 29 of of IN cord-012719-5qa0e4xt 159 30 Crete Crete NNP cord-012719-5qa0e4xt 159 31 ( ( -LRB- cord-012719-5qa0e4xt 159 32 Greece Greece NNP cord-012719-5qa0e4xt 159 33 ) ) -RRB- cord-012719-5qa0e4xt 159 34 Epidemiology Epidemiology NNP cord-012719-5qa0e4xt 159 35 of of IN cord-012719-5qa0e4xt 159 36 the the DT cord-012719-5qa0e4xt 159 37 pseudo pseudo JJ cord-012719-5qa0e4xt 159 38 - - JJ cord-012719-5qa0e4xt 159 39 exfoliation exfoliation NN cord-012719-5qa0e4xt 159 40 syndrome syndrome NN cord-012719-5qa0e4xt 159 41 , , , cord-012719-5qa0e4xt 159 42 a a DT cord-012719-5qa0e4xt 159 43 review review NN cord-012719-5qa0e4xt 160 1 The the DT cord-012719-5qa0e4xt 160 2 prevalence prevalence NN cord-012719-5qa0e4xt 160 3 of of IN cord-012719-5qa0e4xt 160 4 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 160 5 syndrome syndrome NN cord-012719-5qa0e4xt 160 6 in in IN cord-012719-5qa0e4xt 160 7 Chinese chinese JJ cord-012719-5qa0e4xt 160 8 people people NNS cord-012719-5qa0e4xt 160 9 Prevalence prevalence NN cord-012719-5qa0e4xt 160 10 of of IN cord-012719-5qa0e4xt 160 11 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 160 12 syndrome syndrome NN cord-012719-5qa0e4xt 160 13 in in IN cord-012719-5qa0e4xt 160 14 an an DT cord-012719-5qa0e4xt 160 15 isolated isolated JJ cord-012719-5qa0e4xt 160 16 island island NN cord-012719-5qa0e4xt 160 17 population population NN cord-012719-5qa0e4xt 160 18 of of IN cord-012719-5qa0e4xt 160 19 Korea Korea NNP cord-012719-5qa0e4xt 160 20 : : : cord-012719-5qa0e4xt 160 21 the the DT cord-012719-5qa0e4xt 160 22 Woodo Woodo NNP cord-012719-5qa0e4xt 160 23 study study NN cord-012719-5qa0e4xt 160 24 LOXL1 loxl1 NN cord-012719-5qa0e4xt 160 25 gene gene NN cord-012719-5qa0e4xt 160 26 polymorphism polymorphism NN cord-012719-5qa0e4xt 160 27 with with IN cord-012719-5qa0e4xt 160 28 exfoliation exfoliation NN cord-012719-5qa0e4xt 160 29 syndrome syndrome NN cord-012719-5qa0e4xt 160 30 / / SYM cord-012719-5qa0e4xt 160 31 exfoliation exfoliation NN cord-012719-5qa0e4xt 160 32 glaucoma glaucoma NN cord-012719-5qa0e4xt 160 33 : : : cord-012719-5qa0e4xt 160 34 a a DT cord-012719-5qa0e4xt 160 35 meta meta NN cord-012719-5qa0e4xt 160 36 - - HYPH cord-012719-5qa0e4xt 160 37 analysis analysis NN cord-012719-5qa0e4xt 160 38 The the DT cord-012719-5qa0e4xt 160 39 distribution distribution NN cord-012719-5qa0e4xt 160 40 of of IN cord-012719-5qa0e4xt 160 41 intraocular intraocular JJ cord-012719-5qa0e4xt 160 42 pressure pressure NN cord-012719-5qa0e4xt 160 43 and and CC cord-012719-5qa0e4xt 160 44 associated associate VBD cord-012719-5qa0e4xt 160 45 systemic systemic JJ cord-012719-5qa0e4xt 160 46 factors factor NNS cord-012719-5qa0e4xt 160 47 in in IN cord-012719-5qa0e4xt 160 48 a a DT cord-012719-5qa0e4xt 160 49 Korean korean JJ cord-012719-5qa0e4xt 160 50 population population NN cord-012719-5qa0e4xt 160 51 : : : cord-012719-5qa0e4xt 160 52 The the DT cord-012719-5qa0e4xt 160 53 Korea Korea NNP cord-012719-5qa0e4xt 160 54 National National NNP cord-012719-5qa0e4xt 160 55 Health Health NNP cord-012719-5qa0e4xt 160 56 and and CC cord-012719-5qa0e4xt 160 57 Nutrition Nutrition NNP cord-012719-5qa0e4xt 160 58 Examination Examination NNP cord-012719-5qa0e4xt 160 59 Survey Survey NNP cord-012719-5qa0e4xt 160 60 Blood Blood NNP cord-012719-5qa0e4xt 160 61 flow flow NN cord-012719-5qa0e4xt 160 62 in in IN cord-012719-5qa0e4xt 160 63 glaucoma glaucoma NN cord-012719-5qa0e4xt 160 64 Microvascular Microvascular NNP cord-012719-5qa0e4xt 160 65 blood blood NN cord-012719-5qa0e4xt 160 66 flow flow NN cord-012719-5qa0e4xt 160 67 of of IN cord-012719-5qa0e4xt 160 68 the the DT cord-012719-5qa0e4xt 160 69 optic optic JJ cord-012719-5qa0e4xt 160 70 nerve nerve NN cord-012719-5qa0e4xt 160 71 head head NN cord-012719-5qa0e4xt 160 72 and and CC cord-012719-5qa0e4xt 160 73 peripapillary peripapillary JJ cord-012719-5qa0e4xt 160 74 retina retina NN cord-012719-5qa0e4xt 160 75 in in IN cord-012719-5qa0e4xt 160 76 unilateral unilateral JJ cord-012719-5qa0e4xt 160 77 exfoliation exfoliation NN cord-012719-5qa0e4xt 160 78 syndrome syndrome NN cord-012719-5qa0e4xt 160 79 Evaluation Evaluation NNP cord-012719-5qa0e4xt 160 80 of of IN cord-012719-5qa0e4xt 160 81 lamina lamina NNP cord-012719-5qa0e4xt 160 82 cribrosa cribrosa NNP cord-012719-5qa0e4xt 160 83 in in IN cord-012719-5qa0e4xt 160 84 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 160 85 syndrome syndrome NN cord-012719-5qa0e4xt 160 86 using use VBG cord-012719-5qa0e4xt 160 87 spectral spectral JJ cord-012719-5qa0e4xt 160 88 - - HYPH cord-012719-5qa0e4xt 160 89 domain domain NN cord-012719-5qa0e4xt 160 90 optical optical JJ cord-012719-5qa0e4xt 160 91 coherence coherence NN cord-012719-5qa0e4xt 161 1 tomography tomography NNP cord-012719-5qa0e4xt 161 2 enhanced enhanced JJ cord-012719-5qa0e4xt 161 3 depth depth NN cord-012719-5qa0e4xt 161 4 imaging imaging NNP cord-012719-5qa0e4xt 161 5 Evaluation Evaluation NNP cord-012719-5qa0e4xt 161 6 of of IN cord-012719-5qa0e4xt 161 7 lamina lamina NNP cord-012719-5qa0e4xt 161 8 cribrosa cribrosa NNP cord-012719-5qa0e4xt 161 9 and and CC cord-012719-5qa0e4xt 161 10 choroid choroid NN cord-012719-5qa0e4xt 161 11 in in IN cord-012719-5qa0e4xt 161 12 nonglaucomatous nonglaucomatous JJ cord-012719-5qa0e4xt 161 13 patients patient NNS cord-012719-5qa0e4xt 161 14 with with IN cord-012719-5qa0e4xt 161 15 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 161 16 syndrome syndrome NN cord-012719-5qa0e4xt 161 17 using use VBG cord-012719-5qa0e4xt 161 18 spectral spectral JJ cord-012719-5qa0e4xt 161 19 - - HYPH cord-012719-5qa0e4xt 161 20 domain domain NN cord-012719-5qa0e4xt 161 21 optical optical JJ cord-012719-5qa0e4xt 161 22 coherence coherence NN cord-012719-5qa0e4xt 161 23 tomography tomography NN cord-012719-5qa0e4xt 161 24 Schlötzer Schlötzer NNP cord-012719-5qa0e4xt 161 25 - - HYPH cord-012719-5qa0e4xt 161 26 Schrehardt Schrehardt NNP cord-012719-5qa0e4xt 161 27 U. U. NNP cord-012719-5qa0e4xt 161 28 Evaluation Evaluation NNP cord-012719-5qa0e4xt 161 29 of of IN cord-012719-5qa0e4xt 161 30 lamina lamina NNP cord-012719-5qa0e4xt 161 31 cribrosa cribrosa NNP cord-012719-5qa0e4xt 161 32 and and CC cord-012719-5qa0e4xt 161 33 peripapillary peripapillary JJ cord-012719-5qa0e4xt 161 34 sclera sclera NN cord-012719-5qa0e4xt 161 35 stiffness stiffness NN cord-012719-5qa0e4xt 161 36 in in IN cord-012719-5qa0e4xt 161 37 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 161 38 and and CC cord-012719-5qa0e4xt 161 39 normal normal JJ cord-012719-5qa0e4xt 161 40 eyes eye NNS cord-012719-5qa0e4xt 161 41 by by IN cord-012719-5qa0e4xt 161 42 atomic atomic JJ cord-012719-5qa0e4xt 161 43 force force NN cord-012719-5qa0e4xt 161 44 microscopy microscopy NNP cord-012719-5qa0e4xt 162 1 Central central JJ cord-012719-5qa0e4xt 162 2 retinal retinal JJ cord-012719-5qa0e4xt 162 3 artery artery NN cord-012719-5qa0e4xt 162 4 and and CC cord-012719-5qa0e4xt 163 1 vein vein NN cord-012719-5qa0e4xt 163 2 collapse collapse NN cord-012719-5qa0e4xt 163 3 pressure pressure NN cord-012719-5qa0e4xt 163 4 in in IN cord-012719-5qa0e4xt 163 5 eyes eye NNS cord-012719-5qa0e4xt 163 6 with with IN cord-012719-5qa0e4xt 163 7 chronic chronic JJ cord-012719-5qa0e4xt 163 8 open open JJ cord-012719-5qa0e4xt 163 9 angle angle NN cord-012719-5qa0e4xt 163 10 glaucoma glaucoma NN cord-012719-5qa0e4xt 163 11 Pseudoexfoliation Pseudoexfoliation NNP cord-012719-5qa0e4xt 163 12 of of IN cord-012719-5qa0e4xt 163 13 the the DT cord-012719-5qa0e4xt 163 14 lens lens JJ cord-012719-5qa0e4xt 163 15 capsule capsule NN cord-012719-5qa0e4xt 163 16 II II NNP cord-012719-5qa0e4xt 163 17 . . . cord-012719-5qa0e4xt 164 1 Development development NN cord-012719-5qa0e4xt 164 2 of of IN cord-012719-5qa0e4xt 164 3 the the DT cord-012719-5qa0e4xt 164 4 exfoliation exfoliation NN cord-012719-5qa0e4xt 164 5 syndrome syndrome NN cord-012719-5qa0e4xt 164 6 Unilateral unilateral JJ cord-012719-5qa0e4xt 164 7 exfoliation exfoliation NN cord-012719-5qa0e4xt 164 8 syndrome syndrome NN cord-012719-5qa0e4xt 164 9 : : : cord-012719-5qa0e4xt 164 10 conversion conversion NN cord-012719-5qa0e4xt 164 11 to to IN cord-012719-5qa0e4xt 164 12 bilateral bilateral JJ cord-012719-5qa0e4xt 164 13 exfoliation exfoliation NN cord-012719-5qa0e4xt 164 14 and and CC cord-012719-5qa0e4xt 164 15 to to IN cord-012719-5qa0e4xt 164 16 glaucoma glaucoma NN cord-012719-5qa0e4xt 164 17 : : : cord-012719-5qa0e4xt 164 18 a a DT cord-012719-5qa0e4xt 164 19 prospective prospective JJ cord-012719-5qa0e4xt 164 20 10-year 10-year CD cord-012719-5qa0e4xt 164 21 follow follow NN cord-012719-5qa0e4xt 164 22 - - HYPH cord-012719-5qa0e4xt 164 23 up up NN cord-012719-5qa0e4xt 164 24 study study NN cord-012719-5qa0e4xt 164 25 Iris Iris NNP cord-012719-5qa0e4xt 164 26 indocyanine indocyanine NN cord-012719-5qa0e4xt 164 27 green green JJ cord-012719-5qa0e4xt 164 28 angiography angiography NN cord-012719-5qa0e4xt 164 29 in in IN cord-012719-5qa0e4xt 164 30 pseudoexfoliation pseudoexfoliation NN cord-012719-5qa0e4xt 164 31 syndrome syndrome NN cord-012719-5qa0e4xt 164 32 and and CC cord-012719-5qa0e4xt 164 33 capsular capsular JJ cord-012719-5qa0e4xt 164 34 glaucoma glaucoma NN cord-012719-5qa0e4xt 164 35 Interocular Interocular NNP cord-012719-5qa0e4xt 164 36 differences difference NNS cord-012719-5qa0e4xt 164 37 in in IN cord-012719-5qa0e4xt 164 38 optic optic JJ cord-012719-5qa0e4xt 164 39 disc disc NN cord-012719-5qa0e4xt 164 40 configuration configuration NN cord-012719-5qa0e4xt 164 41 in in IN cord-012719-5qa0e4xt 164 42 the the DT cord-012719-5qa0e4xt 164 43 unilateral unilateral JJ cord-012719-5qa0e4xt 164 44 exfoliation exfoliation NN cord-012719-5qa0e4xt 164 45 syndrome syndrome NN cord-012719-5qa0e4xt 164 46 Optic optic JJ cord-012719-5qa0e4xt 164 47 nerve nerve NN cord-012719-5qa0e4xt 164 48 head head NN cord-012719-5qa0e4xt 164 49 topography topography NN cord-012719-5qa0e4xt 164 50 in in IN cord-012719-5qa0e4xt 164 51 nonglaucomatous nonglaucomatous NNP cord-012719-5qa0e4xt 164 52 , , , cord-012719-5qa0e4xt 164 53 normotensive normotensive JJ cord-012719-5qa0e4xt 164 54 patients patient NNS cord-012719-5qa0e4xt 164 55 with with IN cord-012719-5qa0e4xt 164 56 unilateral unilateral JJ cord-012719-5qa0e4xt 164 57 exfoliation exfoliation NN cord-012719-5qa0e4xt 164 58 syndrome syndrome NN cord-012719-5qa0e4xt 164 59 . . . cord-012719-5qa0e4xt 165 1 Graefe Graefe NNP cord-012719-5qa0e4xt 165 2 's 's POS cord-012719-5qa0e4xt 165 3 Arch Arch NNP cord-012719-5qa0e4xt 165 4 Clin Clin NNP cord-012719-5qa0e4xt 165 5 Exp Exp NNP cord-012719-5qa0e4xt 165 6 Ophthalmol Ophthalmol NNP cord-012719-5qa0e4xt 165 7 Conflict Conflict NNP cord-012719-5qa0e4xt 165 8 of of IN cord-012719-5qa0e4xt 165 9 interest interest NN cord-012719-5qa0e4xt 166 1 The the DT cord-012719-5qa0e4xt 166 2 authors author NNS cord-012719-5qa0e4xt 166 3 declare declare VBP cord-012719-5qa0e4xt 166 4 that that IN cord-012719-5qa0e4xt 166 5 they -PRON- PRP cord-012719-5qa0e4xt 166 6 have have VBP cord-012719-5qa0e4xt 166 7 no no DT cord-012719-5qa0e4xt 166 8 conflict conflict NN cord-012719-5qa0e4xt 166 9 of of IN cord-012719-5qa0e4xt 166 10 interest interest NN cord-012719-5qa0e4xt 166 11 . . . cord-012719-5qa0e4xt 167 1 Publisher publisher NN cord-012719-5qa0e4xt 167 2 's 's POS cord-012719-5qa0e4xt 167 3 note note NN cord-012719-5qa0e4xt 167 4 Springer Springer NNP cord-012719-5qa0e4xt 167 5 Nature Nature NNP cord-012719-5qa0e4xt 167 6 remains remain VBZ cord-012719-5qa0e4xt 167 7 neutral neutral JJ cord-012719-5qa0e4xt 167 8 with with IN cord-012719-5qa0e4xt 167 9 regard regard NN cord-012719-5qa0e4xt 167 10 to to IN cord-012719-5qa0e4xt 167 11 jurisdictional jurisdictional JJ cord-012719-5qa0e4xt 167 12 claims claim NNS cord-012719-5qa0e4xt 167 13 in in IN cord-012719-5qa0e4xt 167 14 published publish VBN cord-012719-5qa0e4xt 167 15 maps map NNS cord-012719-5qa0e4xt 167 16 and and CC cord-012719-5qa0e4xt 167 17 institutional institutional JJ cord-012719-5qa0e4xt 167 18 affiliations affiliation NNS cord-012719-5qa0e4xt 167 19 . . .