id	sid	tid	token	lemma	pos
cord-017142-vx3rgs4r	1	1	key	key	JJ
cord-017142-vx3rgs4r	1	2	:	:	:
cord-017142-vx3rgs4r	1	3	cord-017142-vx3rgs4r	cord-017142-vx3rgs4r	.
cord-017142-vx3rgs4r	1	4	authors	author	NNS
cord-017142-vx3rgs4r	1	5	:	:	:
cord-017142-vx3rgs4r	1	6	Nair	Nair	NNP
cord-017142-vx3rgs4r	1	7	,	,	,
cord-017142-vx3rgs4r	1	8	Ranjit	Ranjit	NNP
cord-017142-vx3rgs4r	1	9	;	;	:
cord-017142-vx3rgs4r	1	10	Patel	Patel	NNP
cord-017142-vx3rgs4r	1	11	,	,	,
cord-017142-vx3rgs4r	1	12	Krina	Krina	NNP
cord-017142-vx3rgs4r	1	13	title	title	NN
cord-017142-vx3rgs4r	1	14	:	:	:
cord-017142-vx3rgs4r	2	1	What	what	WP
cord-017142-vx3rgs4r	2	2	the	the	DT
cord-017142-vx3rgs4r	2	3	Intensivists	Intensivists	NNPS
cord-017142-vx3rgs4r	2	4	Need	need	VBP
cord-017142-vx3rgs4r	2	5	to	to	TO
cord-017142-vx3rgs4r	2	6	Know	know	VB
cord-017142-vx3rgs4r	2	7	About	about	IN
cord-017142-vx3rgs4r	2	8	Critically	critically	RB
cord-017142-vx3rgs4r	2	9	Ill	Ill	NNP
cord-017142-vx3rgs4r	2	10	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	2	11	Patients	patient	NNS
cord-017142-vx3rgs4r	2	12	date	date	NN
cord-017142-vx3rgs4r	3	1	:	:	:
cord-017142-vx3rgs4r	3	2	2019	2019	CD
cord-017142-vx3rgs4r	3	3	-	-	HYPH
cord-017142-vx3rgs4r	3	4	07	07	CD
cord-017142-vx3rgs4r	3	5	-	-	HYPH
cord-017142-vx3rgs4r	3	6	09	09	CD
cord-017142-vx3rgs4r	3	7	journal	journal	NN
cord-017142-vx3rgs4r	3	8	:	:	:
cord-017142-vx3rgs4r	4	1	Oncologic	Oncologic	NNP
cord-017142-vx3rgs4r	4	2	Critical	Critical	NNP
cord-017142-vx3rgs4r	4	3	Care	Care	NNP
cord-017142-vx3rgs4r	4	4	DOI	doi	NN
cord-017142-vx3rgs4r	4	5	:	:	:
cord-017142-vx3rgs4r	5	1	10.1007/978	10.1007/978	LS
cord-017142-vx3rgs4r	5	2	-	-	SYM
cord-017142-vx3rgs4r	5	3	3	3	CD
cord-017142-vx3rgs4r	5	4	-	-	HYPH
cord-017142-vx3rgs4r	5	5	319	319	CD
cord-017142-vx3rgs4r	5	6	-	-	HYPH
cord-017142-vx3rgs4r	5	7	74588	74588	CD
cord-017142-vx3rgs4r	5	8	-	-	HYPH
cord-017142-vx3rgs4r	5	9	6_98	6_98	CD
cord-017142-vx3rgs4r	5	10	sha	sha	NNP
cord-017142-vx3rgs4r	5	11	:	:	:
cord-017142-vx3rgs4r	6	1	52fcbbab38266dc6779fe3a9a004439fcd07290b	52fcbbab38266dc6779fe3a9a004439fcd07290b	CD
cord-017142-vx3rgs4r	6	2	doc_id	doc_id	CD
cord-017142-vx3rgs4r	6	3	:	:	:
cord-017142-vx3rgs4r	6	4	17142	17142	CD
cord-017142-vx3rgs4r	6	5	cord_uid	cord_uid	NNS
cord-017142-vx3rgs4r	6	6	:	:	:
cord-017142-vx3rgs4r	6	7	vx3rgs4r	vx3rgs4r	NNP
cord-017142-vx3rgs4r	6	8	Multiple	multiple	JJ
cord-017142-vx3rgs4r	6	9	myeloma	myeloma	NN
cord-017142-vx3rgs4r	6	10	(	(	-LRB-
cord-017142-vx3rgs4r	6	11	MM	MM	NNP
cord-017142-vx3rgs4r	6	12	)	)	-RRB-
cord-017142-vx3rgs4r	6	13	is	be	VBZ
cord-017142-vx3rgs4r	6	14	a	a	DT
cord-017142-vx3rgs4r	6	15	hematological	hematological	JJ
cord-017142-vx3rgs4r	6	16	malignancy	malignancy	NN
cord-017142-vx3rgs4r	6	17	characterized	characterize	VBN
cord-017142-vx3rgs4r	6	18	by	by	IN
cord-017142-vx3rgs4r	6	19	an	an	DT
cord-017142-vx3rgs4r	6	20	increase	increase	NN
cord-017142-vx3rgs4r	6	21	in	in	IN
cord-017142-vx3rgs4r	6	22	aberrant	aberrant	JJ
cord-017142-vx3rgs4r	6	23	plasma	plasma	NN
cord-017142-vx3rgs4r	6	24	cells	cell	NNS
cord-017142-vx3rgs4r	6	25	in	in	IN
cord-017142-vx3rgs4r	6	26	the	the	DT
cord-017142-vx3rgs4r	6	27	bone	bone	NN
cord-017142-vx3rgs4r	6	28	marrow	marrow	NN
cord-017142-vx3rgs4r	6	29	leading	lead	VBG
cord-017142-vx3rgs4r	6	30	to	to	IN
cord-017142-vx3rgs4r	6	31	rising	rise	VBG
cord-017142-vx3rgs4r	6	32	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	6	33	protein	protein	NN
cord-017142-vx3rgs4r	6	34	in	in	IN
cord-017142-vx3rgs4r	6	35	serum	serum	NN
cord-017142-vx3rgs4r	6	36	and	and	CC
cord-017142-vx3rgs4r	6	37	urine	urine	NN
cord-017142-vx3rgs4r	6	38	.	.	.
cord-017142-vx3rgs4r	7	1	With	with	IN
cord-017142-vx3rgs4r	7	2	the	the	DT
cord-017142-vx3rgs4r	7	3	introduction	introduction	NN
cord-017142-vx3rgs4r	7	4	of	of	IN
cord-017142-vx3rgs4r	7	5	novel	novel	JJ
cord-017142-vx3rgs4r	7	6	therapies	therapy	NNS
cord-017142-vx3rgs4r	7	7	with	with	IN
cord-017142-vx3rgs4r	7	8	manageable	manageable	JJ
cord-017142-vx3rgs4r	7	9	side	side	NN
cord-017142-vx3rgs4r	7	10	effects	effect	NNS
cord-017142-vx3rgs4r	7	11	,	,	,
cord-017142-vx3rgs4r	7	12	this	this	DT
cord-017142-vx3rgs4r	7	13	incurable	incurable	JJ
cord-017142-vx3rgs4r	7	14	disease	disease	NN
cord-017142-vx3rgs4r	7	15	has	have	VBZ
cord-017142-vx3rgs4r	7	16	evolved	evolve	VBN
cord-017142-vx3rgs4r	7	17	into	into	IN
cord-017142-vx3rgs4r	7	18	a	a	DT
cord-017142-vx3rgs4r	7	19	chronic	chronic	JJ
cord-017142-vx3rgs4r	7	20	disease	disease	NN
cord-017142-vx3rgs4r	7	21	with	with	IN
cord-017142-vx3rgs4r	7	22	an	an	DT
cord-017142-vx3rgs4r	7	23	acceptable	acceptable	JJ
cord-017142-vx3rgs4r	7	24	quality	quality	NN
cord-017142-vx3rgs4r	7	25	of	of	IN
cord-017142-vx3rgs4r	7	26	life	life	NN
cord-017142-vx3rgs4r	7	27	for	for	IN
cord-017142-vx3rgs4r	7	28	the	the	DT
cord-017142-vx3rgs4r	7	29	majority	majority	NN
cord-017142-vx3rgs4r	7	30	of	of	IN
cord-017142-vx3rgs4r	7	31	patients	patient	NNS
cord-017142-vx3rgs4r	7	32	.	.	.
cord-017142-vx3rgs4r	8	1	Accordingly	accordingly	RB
cord-017142-vx3rgs4r	8	2	,	,	,
cord-017142-vx3rgs4r	8	3	management	management	NN
cord-017142-vx3rgs4r	8	4	of	of	IN
cord-017142-vx3rgs4r	8	5	acute	acute	JJ
cord-017142-vx3rgs4r	8	6	complications	complication	NNS
cord-017142-vx3rgs4r	8	7	is	be	VBZ
cord-017142-vx3rgs4r	8	8	fundamental	fundamental	JJ
cord-017142-vx3rgs4r	8	9	in	in	IN
cord-017142-vx3rgs4r	8	10	reducing	reduce	VBG
cord-017142-vx3rgs4r	8	11	the	the	DT
cord-017142-vx3rgs4r	8	12	morbidity	morbidity	NN
cord-017142-vx3rgs4r	8	13	and	and	CC
cord-017142-vx3rgs4r	8	14	mortality	mortality	NN
cord-017142-vx3rgs4r	8	15	in	in	IN
cord-017142-vx3rgs4r	8	16	MM	MM	NNP
cord-017142-vx3rgs4r	8	17	.	.	.
cord-017142-vx3rgs4r	9	1	MM	MM	NNP
cord-017142-vx3rgs4r	9	2	emergencies	emergency	NNS
cord-017142-vx3rgs4r	9	3	include	include	VBP
cord-017142-vx3rgs4r	9	4	symptoms	symptom	NNS
cord-017142-vx3rgs4r	9	5	and	and	CC
cord-017142-vx3rgs4r	9	6	signs	sign	NNS
cord-017142-vx3rgs4r	9	7	related	relate	VBN
cord-017142-vx3rgs4r	9	8	directly	directly	RB
cord-017142-vx3rgs4r	9	9	to	to	IN
cord-017142-vx3rgs4r	9	10	the	the	DT
cord-017142-vx3rgs4r	9	11	disease	disease	NN
cord-017142-vx3rgs4r	9	12	and/or	and/or	CC
cord-017142-vx3rgs4r	9	13	to	to	IN
cord-017142-vx3rgs4r	9	14	the	the	DT
cord-017142-vx3rgs4r	9	15	treatment	treatment	NN
cord-017142-vx3rgs4r	9	16	;	;	:
cord-017142-vx3rgs4r	9	17	many	many	JJ
cord-017142-vx3rgs4r	9	18	organs	organ	NNS
cord-017142-vx3rgs4r	9	19	may	may	MD
cord-017142-vx3rgs4r	9	20	be	be	VB
cord-017142-vx3rgs4r	9	21	involved	involve	VBN
cord-017142-vx3rgs4r	9	22	including	include	VBG
cord-017142-vx3rgs4r	9	23	,	,	,
cord-017142-vx3rgs4r	9	24	but	but	CC
cord-017142-vx3rgs4r	9	25	not	not	RB
cord-017142-vx3rgs4r	9	26	limited	limited	JJ
cord-017142-vx3rgs4r	9	27	to	to	IN
cord-017142-vx3rgs4r	9	28	,	,	,
cord-017142-vx3rgs4r	9	29	renal	renal	JJ
cord-017142-vx3rgs4r	9	30	,	,	,
cord-017142-vx3rgs4r	9	31	cardiovascular	cardiovascular	JJ
cord-017142-vx3rgs4r	9	32	,	,	,
cord-017142-vx3rgs4r	9	33	neurologic	neurologic	JJ
cord-017142-vx3rgs4r	9	34	,	,	,
cord-017142-vx3rgs4r	9	35	hematologic	hematologic	JJ
cord-017142-vx3rgs4r	9	36	,	,	,
cord-017142-vx3rgs4r	9	37	and	and	CC
cord-017142-vx3rgs4r	9	38	infectious	infectious	JJ
cord-017142-vx3rgs4r	9	39	complications	complication	NNS
cord-017142-vx3rgs4r	9	40	.	.	.
cord-017142-vx3rgs4r	10	1	This	this	DT
cord-017142-vx3rgs4r	10	2	review	review	NN
cord-017142-vx3rgs4r	10	3	will	will	MD
cord-017142-vx3rgs4r	10	4	focus	focus	VB
cord-017142-vx3rgs4r	10	5	on	on	IN
cord-017142-vx3rgs4r	10	6	the	the	DT
cord-017142-vx3rgs4r	10	7	numerous	numerous	JJ
cord-017142-vx3rgs4r	10	8	approaches	approach	NNS
cord-017142-vx3rgs4r	10	9	that	that	WDT
cord-017142-vx3rgs4r	10	10	are	be	VBP
cord-017142-vx3rgs4r	10	11	aimed	aim	VBN
cord-017142-vx3rgs4r	10	12	at	at	IN
cord-017142-vx3rgs4r	10	13	managing	manage	VBG
cord-017142-vx3rgs4r	10	14	these	these	DT
cord-017142-vx3rgs4r	10	15	complications	complication	NNS
cord-017142-vx3rgs4r	10	16	.	.	.
cord-017142-vx3rgs4r	11	1	MM	MM	NNP
cord-017142-vx3rgs4r	11	2	is	be	VBZ
cord-017142-vx3rgs4r	11	3	a	a	DT
cord-017142-vx3rgs4r	11	4	hematological	hematological	JJ
cord-017142-vx3rgs4r	11	5	malignancy	malignancy	NN
cord-017142-vx3rgs4r	11	6	characterized	characterize	VBN
cord-017142-vx3rgs4r	11	7	by	by	IN
cord-017142-vx3rgs4r	11	8	an	an	DT
cord-017142-vx3rgs4r	11	9	increase	increase	NN
cord-017142-vx3rgs4r	11	10	in	in	IN
cord-017142-vx3rgs4r	11	11	aberrant	aberrant	JJ
cord-017142-vx3rgs4r	11	12	plasma	plasma	NN
cord-017142-vx3rgs4r	11	13	cells	cell	NNS
cord-017142-vx3rgs4r	11	14	in	in	IN
cord-017142-vx3rgs4r	11	15	the	the	DT
cord-017142-vx3rgs4r	11	16	bone	bone	NN
cord-017142-vx3rgs4r	11	17	marrow	marrow	NN
cord-017142-vx3rgs4r	11	18	leading	lead	VBG
cord-017142-vx3rgs4r	11	19	to	to	IN
cord-017142-vx3rgs4r	11	20	rising	rise	VBG
cord-017142-vx3rgs4r	11	21	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	11	22	proteins	protein	NNS
cord-017142-vx3rgs4r	11	23	in	in	IN
cord-017142-vx3rgs4r	11	24	the	the	DT
cord-017142-vx3rgs4r	11	25	serum	serum	NN
cord-017142-vx3rgs4r	11	26	and	and	CC
cord-017142-vx3rgs4r	11	27	urine	urine	NN
cord-017142-vx3rgs4r	11	28	.	.	.
cord-017142-vx3rgs4r	12	1	In	in	IN
cord-017142-vx3rgs4r	12	2	general	general	JJ
cord-017142-vx3rgs4r	12	3	,	,	,
cord-017142-vx3rgs4r	12	4	it	-PRON-	PRP
cord-017142-vx3rgs4r	12	5	is	be	VBZ
cord-017142-vx3rgs4r	12	6	a	a	DT
cord-017142-vx3rgs4r	12	7	disease	disease	NN
cord-017142-vx3rgs4r	12	8	of	of	IN
cord-017142-vx3rgs4r	12	9	older	old	JJR
cord-017142-vx3rgs4r	12	10	adults	adult	NNS
cord-017142-vx3rgs4r	12	11	;	;	:
cord-017142-vx3rgs4r	12	12	however	however	RB
cord-017142-vx3rgs4r	12	13	,	,	,
cord-017142-vx3rgs4r	12	14	MM	MM	NNP
cord-017142-vx3rgs4r	12	15	may	may	MD
cord-017142-vx3rgs4r	12	16	effect	effect	VB
cord-017142-vx3rgs4r	12	17	younger	young	JJR
cord-017142-vx3rgs4r	12	18	patients	patient	NNS
cord-017142-vx3rgs4r	12	19	as	as	RB
cord-017142-vx3rgs4r	12	20	well	well	RB
cord-017142-vx3rgs4r	12	21	:	:	:
cord-017142-vx3rgs4r	12	22	15	15	CD
cord-017142-vx3rgs4r	12	23	%	%	NN
cord-017142-vx3rgs4r	12	24	are	be	VBP
cord-017142-vx3rgs4r	12	25	<	<	XX
cord-017142-vx3rgs4r	12	26	50	50	CD
cord-017142-vx3rgs4r	12	27	years	year	NNS
cord-017142-vx3rgs4r	12	28	,	,	,
cord-017142-vx3rgs4r	12	29	3	3	CD
cord-017142-vx3rgs4r	12	30	%	%	NN
cord-017142-vx3rgs4r	12	31	are	be	VBP
cord-017142-vx3rgs4r	12	32	<	<	XX
cord-017142-vx3rgs4r	12	33	40	40	CD
cord-017142-vx3rgs4r	12	34	years	year	NNS
cord-017142-vx3rgs4r	12	35	,	,	,
cord-017142-vx3rgs4r	12	36	and	and	CC
cord-017142-vx3rgs4r	12	37	0.2	0.2	CD
cord-017142-vx3rgs4r	12	38	%	%	NN
cord-017142-vx3rgs4r	12	39	are	be	VBP
cord-017142-vx3rgs4r	12	40	<	<	XX
cord-017142-vx3rgs4r	12	41	30	30	CD
cord-017142-vx3rgs4r	12	42	years	year	NNS
cord-017142-vx3rgs4r	12	43	in	in	IN
cord-017142-vx3rgs4r	12	44	age	age	NN
cord-017142-vx3rgs4r	12	45	[	[	-LRB-
cord-017142-vx3rgs4r	12	46	74	74	CD
cord-017142-vx3rgs4r	12	47	]	]	-RRB-
cord-017142-vx3rgs4r	12	48	.	.	.
cord-017142-vx3rgs4r	13	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	13	2	accounts	account	VBZ
cord-017142-vx3rgs4r	13	3	for	for	IN
cord-017142-vx3rgs4r	13	4	about	about	RB
cord-017142-vx3rgs4r	13	5	10	10	CD
cord-017142-vx3rgs4r	13	6	%	%	NN
cord-017142-vx3rgs4r	13	7	of	of	IN
cord-017142-vx3rgs4r	13	8	hematological	hematological	JJ
cord-017142-vx3rgs4r	13	9	malignancies	malignancy	NNS
cord-017142-vx3rgs4r	13	10	in	in	IN
cord-017142-vx3rgs4r	13	11	the	the	DT
cord-017142-vx3rgs4r	13	12	United	United	NNP
cord-017142-vx3rgs4r	13	13	States	States	NNP
cord-017142-vx3rgs4r	13	14	,	,	,
cord-017142-vx3rgs4r	13	15	with	with	IN
cord-017142-vx3rgs4r	13	16	an	an	DT
cord-017142-vx3rgs4r	13	17	estimated	estimate	VBN
cord-017142-vx3rgs4r	13	18	30,770	30,770	CD
cord-017142-vx3rgs4r	13	19	new	new	JJ
cord-017142-vx3rgs4r	13	20	cases	case	NNS
cord-017142-vx3rgs4r	13	21	in	in	IN
cord-017142-vx3rgs4r	13	22	2018	2018	CD
cord-017142-vx3rgs4r	13	23	.	.	.
cord-017142-vx3rgs4r	14	1	Patients	patient	NNS
cord-017142-vx3rgs4r	14	2	often	often	RB
cord-017142-vx3rgs4r	14	3	present	present	JJ
cord-017142-vx3rgs4r	14	4	with	with	IN
cord-017142-vx3rgs4r	14	5	osteolytic	osteolytic	JJ
cord-017142-vx3rgs4r	14	6	bone	bone	NN
cord-017142-vx3rgs4r	14	7	lesions	lesion	NNS
cord-017142-vx3rgs4r	14	8	,	,	,
cord-017142-vx3rgs4r	14	9	fractures	fracture	NNS
cord-017142-vx3rgs4r	14	10	,	,	,
cord-017142-vx3rgs4r	14	11	bone	bone	NN
cord-017142-vx3rgs4r	14	12	pain	pain	NN
cord-017142-vx3rgs4r	14	13	,	,	,
cord-017142-vx3rgs4r	14	14	progressive	progressive	JJ
cord-017142-vx3rgs4r	14	15	anemia	anemia	NN
cord-017142-vx3rgs4r	14	16	,	,	,
cord-017142-vx3rgs4r	14	17	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	14	18	,	,	,
cord-017142-vx3rgs4r	14	19	renal	renal	JJ
cord-017142-vx3rgs4r	14	20	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	14	21	,	,	,
cord-017142-vx3rgs4r	14	22	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	14	23	infections	infection	NNS
cord-017142-vx3rgs4r	14	24	,	,	,
cord-017142-vx3rgs4r	14	25	and/or	and/or	CC
cord-017142-vx3rgs4r	14	26	bleeding	bleed	VBG
cord-017142-vx3rgs4r	14	27	.	.	.
cord-017142-vx3rgs4r	15	1	If	if	IN
cord-017142-vx3rgs4r	15	2	not	not	RB
cord-017142-vx3rgs4r	15	3	treated	treat	VBN
cord-017142-vx3rgs4r	15	4	appropriately	appropriately	RB
cord-017142-vx3rgs4r	15	5	and	and	CC
cord-017142-vx3rgs4r	15	6	urgently	urgently	RB
cord-017142-vx3rgs4r	15	7	,	,	,
cord-017142-vx3rgs4r	15	8	any	any	DT
cord-017142-vx3rgs4r	15	9	of	of	IN
cord-017142-vx3rgs4r	15	10	these	these	DT
cord-017142-vx3rgs4r	15	11	may	may	MD
cord-017142-vx3rgs4r	15	12	lead	lead	VB
cord-017142-vx3rgs4r	15	13	to	to	IN
cord-017142-vx3rgs4r	15	14	death	death	NN
cord-017142-vx3rgs4r	15	15	.	.	.
cord-017142-vx3rgs4r	16	1	The	the	DT
cord-017142-vx3rgs4r	16	2	introduction	introduction	NN
cord-017142-vx3rgs4r	16	3	of	of	IN
cord-017142-vx3rgs4r	16	4	novel	novel	JJ
cord-017142-vx3rgs4r	16	5	agents	agent	NNS
cord-017142-vx3rgs4r	16	6	to	to	IN
cord-017142-vx3rgs4r	16	7	the	the	DT
cord-017142-vx3rgs4r	16	8	traditional	traditional	JJ
cord-017142-vx3rgs4r	16	9	arsenal	arsenal	NN
cord-017142-vx3rgs4r	16	10	of	of	IN
cord-017142-vx3rgs4r	16	11	drugs	drug	NNS
cord-017142-vx3rgs4r	16	12	comprising	comprise	VBG
cord-017142-vx3rgs4r	16	13	of	of	IN
cord-017142-vx3rgs4r	16	14	steroids	steroid	NNS
cord-017142-vx3rgs4r	16	15	,	,	,
cord-017142-vx3rgs4r	16	16	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	16	17	,	,	,
cord-017142-vx3rgs4r	16	18	and	and	CC
cord-017142-vx3rgs4r	16	19	autologous	autologous	JJ
cord-017142-vx3rgs4r	16	20	stem	stem	NN
cord-017142-vx3rgs4r	16	21	cell	cell	NN
cord-017142-vx3rgs4r	16	22	transplantation	transplantation	NN
cord-017142-vx3rgs4r	16	23	has	have	VBZ
cord-017142-vx3rgs4r	16	24	shifted	shift	VBN
cord-017142-vx3rgs4r	16	25	the	the	DT
cord-017142-vx3rgs4r	16	26	treatment	treatment	NN
cord-017142-vx3rgs4r	16	27	platform	platform	NN
cord-017142-vx3rgs4r	16	28	from	from	IN
cord-017142-vx3rgs4r	16	29	one	one	CD
cord-017142-vx3rgs4r	16	30	which	which	WDT
cord-017142-vx3rgs4r	16	31	often	often	RB
cord-017142-vx3rgs4r	16	32	required	require	VBD
cord-017142-vx3rgs4r	16	33	repeated	repeat	VBD
cord-017142-vx3rgs4r	16	34	acute	acute	JJ
cord-017142-vx3rgs4r	16	35	interventions	intervention	NNS
cord-017142-vx3rgs4r	16	36	to	to	IN
cord-017142-vx3rgs4r	16	37	that	that	DT
cord-017142-vx3rgs4r	16	38	of	of	IN
cord-017142-vx3rgs4r	16	39	a	a	DT
cord-017142-vx3rgs4r	16	40	more	more	RBR
cord-017142-vx3rgs4r	16	41	chronic	chronic	JJ
cord-017142-vx3rgs4r	16	42	manageable	manageable	JJ
cord-017142-vx3rgs4r	16	43	disease	disease	NN
cord-017142-vx3rgs4r	16	44	.	.	.
cord-017142-vx3rgs4r	17	1	As	as	IN
cord-017142-vx3rgs4r	17	2	the	the	DT
cord-017142-vx3rgs4r	17	3	acute	acute	JJ
cord-017142-vx3rgs4r	17	4	complications	complication	NNS
cord-017142-vx3rgs4r	17	5	can	can	MD
cord-017142-vx3rgs4r	17	6	be	be	VB
cord-017142-vx3rgs4r	17	7	potentially	potentially	RB
cord-017142-vx3rgs4r	17	8	fatal	fatal	JJ
cord-017142-vx3rgs4r	17	9	,	,	,
cord-017142-vx3rgs4r	17	10	early	early	JJ
cord-017142-vx3rgs4r	17	11	recognition	recognition	NN
cord-017142-vx3rgs4r	17	12	and	and	CC
cord-017142-vx3rgs4r	17	13	intensive	intensive	JJ
cord-017142-vx3rgs4r	17	14	care	care	NN
cord-017142-vx3rgs4r	17	15	management	management	NN
cord-017142-vx3rgs4r	17	16	is	be	VBZ
cord-017142-vx3rgs4r	17	17	the	the	DT
cord-017142-vx3rgs4r	17	18	key	key	NN
cord-017142-vx3rgs4r	17	19	to	to	IN
cord-017142-vx3rgs4r	17	20	successful	successful	JJ
cord-017142-vx3rgs4r	17	21	outcomes	outcome	NNS
cord-017142-vx3rgs4r	17	22	.	.	.
cord-017142-vx3rgs4r	18	1	These	these	DT
cord-017142-vx3rgs4r	18	2	patients	patient	NNS
cord-017142-vx3rgs4r	18	3	who	who	WP
cord-017142-vx3rgs4r	18	4	present	present	VBP
cord-017142-vx3rgs4r	18	5	with	with	IN
cord-017142-vx3rgs4r	18	6	complications	complication	NNS
cord-017142-vx3rgs4r	18	7	are	be	VBP
cord-017142-vx3rgs4r	18	8	often	often	RB
cord-017142-vx3rgs4r	18	9	excluded	exclude	VBN
cord-017142-vx3rgs4r	18	10	from	from	IN
cord-017142-vx3rgs4r	18	11	MM	MM	NNP
cord-017142-vx3rgs4r	18	12	trials	trial	NNS
cord-017142-vx3rgs4r	18	13	,	,	,
cord-017142-vx3rgs4r	18	14	and	and	CC
cord-017142-vx3rgs4r	18	15	their	-PRON-	PRP$
cord-017142-vx3rgs4r	18	16	prognosis	prognosis	NN
cord-017142-vx3rgs4r	18	17	in	in	IN
cord-017142-vx3rgs4r	18	18	the	the	DT
cord-017142-vx3rgs4r	18	19	modern	modern	JJ
cord-017142-vx3rgs4r	18	20	era	era	NN
cord-017142-vx3rgs4r	18	21	is	be	VBZ
cord-017142-vx3rgs4r	18	22	uncertain	uncertain	JJ
cord-017142-vx3rgs4r	18	23	.	.	.
cord-017142-vx3rgs4r	19	1	Reports	report	NNS
cord-017142-vx3rgs4r	19	2	suggest	suggest	VBP
cord-017142-vx3rgs4r	19	3	that	that	IN
cord-017142-vx3rgs4r	19	4	in	in	IN
cord-017142-vx3rgs4r	19	5	-	-	HYPH
cord-017142-vx3rgs4r	19	6	hospital	hospital	NN
cord-017142-vx3rgs4r	19	7	mortality	mortality	NN
cord-017142-vx3rgs4r	19	8	from	from	IN
cord-017142-vx3rgs4r	19	9	acute	acute	JJ
cord-017142-vx3rgs4r	19	10	complications	complication	NNS
cord-017142-vx3rgs4r	19	11	of	of	IN
cord-017142-vx3rgs4r	19	12	MM	MM	NNP
cord-017142-vx3rgs4r	19	13	has	have	VBZ
cord-017142-vx3rgs4r	19	14	decreased	decrease	VBN
cord-017142-vx3rgs4r	19	15	significantly	significantly	RB
cord-017142-vx3rgs4r	19	16	over	over	IN
cord-017142-vx3rgs4r	19	17	the	the	DT
cord-017142-vx3rgs4r	19	18	past	past	JJ
cord-017142-vx3rgs4r	19	19	decade	decade	NN
cord-017142-vx3rgs4r	19	20	.	.	.
cord-017142-vx3rgs4r	20	1	Continued	continue	VBN
cord-017142-vx3rgs4r	20	2	risk	risk	NN
cord-017142-vx3rgs4r	20	3	factors	factor	NNS
cord-017142-vx3rgs4r	20	4	for	for	IN
cord-017142-vx3rgs4r	20	5	death	death	NN
cord-017142-vx3rgs4r	20	6	in	in	IN
cord-017142-vx3rgs4r	20	7	this	this	DT
cord-017142-vx3rgs4r	20	8	group	group	NN
cord-017142-vx3rgs4r	20	9	of	of	IN
cord-017142-vx3rgs4r	20	10	patients	patient	NNS
cord-017142-vx3rgs4r	20	11	are	be	VBP
cord-017142-vx3rgs4r	20	12	organ	organ	NN
cord-017142-vx3rgs4r	20	13	failure	failure	NN
cord-017142-vx3rgs4r	20	14	,	,	,
cord-017142-vx3rgs4r	20	15	poor	poor	JJ
cord-017142-vx3rgs4r	20	16	chronic	chronic	JJ
cord-017142-vx3rgs4r	20	17	health	health	NN
cord-017142-vx3rgs4r	20	18	status	status	NN
cord-017142-vx3rgs4r	20	19	,	,	,
cord-017142-vx3rgs4r	20	20	and	and	CC
cord-017142-vx3rgs4r	20	21	delayed	delay	VBD
cord-017142-vx3rgs4r	20	22	intensive	intensive	JJ
cord-017142-vx3rgs4r	20	23	care	care	NN
cord-017142-vx3rgs4r	20	24	management	management	NN
cord-017142-vx3rgs4r	20	25	[	[	-LRB-
cord-017142-vx3rgs4r	20	26	98	98	CD
cord-017142-vx3rgs4r	20	27	]	]	-RRB-
cord-017142-vx3rgs4r	20	28	.	.	.
cord-017142-vx3rgs4r	21	1	Despite	despite	IN
cord-017142-vx3rgs4r	21	2	having	have	VBG
cord-017142-vx3rgs4r	21	3	increased	increase	VBN
cord-017142-vx3rgs4r	21	4	life	life	NN
cord-017142-vx3rgs4r	21	5	expectancy	expectancy	NN
cord-017142-vx3rgs4r	21	6	now	now	RB
cord-017142-vx3rgs4r	21	7	,	,	,
cord-017142-vx3rgs4r	21	8	the	the	DT
cord-017142-vx3rgs4r	21	9	majority	majority	NN
cord-017142-vx3rgs4r	21	10	of	of	IN
cord-017142-vx3rgs4r	21	11	MM	MM	NNP
cord-017142-vx3rgs4r	21	12	patients	patient	NNS
cord-017142-vx3rgs4r	21	13	ultimately	ultimately	RB
cord-017142-vx3rgs4r	21	14	develop	develop	VBP
cord-017142-vx3rgs4r	21	15	resistant	resistant	JJ
cord-017142-vx3rgs4r	21	16	subclones	subclone	NNS
cord-017142-vx3rgs4r	21	17	,	,	,
cord-017142-vx3rgs4r	21	18	leading	lead	VBG
cord-017142-vx3rgs4r	21	19	to	to	IN
cord-017142-vx3rgs4r	21	20	disease	disease	NN
cord-017142-vx3rgs4r	21	21	progression	progression	NN
cord-017142-vx3rgs4r	21	22	and	and	CC
cord-017142-vx3rgs4r	21	23	disease	disease	NN
cord-017142-vx3rgs4r	21	24	-	-	HYPH
cord-017142-vx3rgs4r	21	25	related	relate	VBN
cord-017142-vx3rgs4r	21	26	complications	complication	NNS
cord-017142-vx3rgs4r	21	27	.	.	.
cord-017142-vx3rgs4r	22	1	With	with	IN
cord-017142-vx3rgs4r	22	2	increasing	increase	VBG
cord-017142-vx3rgs4r	22	3	complexity	complexity	NN
cord-017142-vx3rgs4r	22	4	of	of	IN
cord-017142-vx3rgs4r	22	5	MM	MM	NNP
cord-017142-vx3rgs4r	22	6	treatments	treatment	NNS
cord-017142-vx3rgs4r	22	7	,	,	,
cord-017142-vx3rgs4r	22	8	patients	patient	NNS
cord-017142-vx3rgs4r	22	9	are	be	VBP
cord-017142-vx3rgs4r	22	10	at	at	IN
cord-017142-vx3rgs4r	22	11	risk	risk	NN
cord-017142-vx3rgs4r	22	12	for	for	IN
cord-017142-vx3rgs4r	22	13	more	more	RBR
cord-017142-vx3rgs4r	22	14	challenging	challenging	JJ
cord-017142-vx3rgs4r	22	15	drug	drug	NN
cord-017142-vx3rgs4r	22	16	toxicities	toxicity	NNS
cord-017142-vx3rgs4r	22	17	.	.	.
cord-017142-vx3rgs4r	23	1	Recognizing	recognize	VBG
cord-017142-vx3rgs4r	23	2	and	and	CC
cord-017142-vx3rgs4r	23	3	managing	manage	VBG
cord-017142-vx3rgs4r	23	4	the	the	DT
cord-017142-vx3rgs4r	23	5	potential	potential	JJ
cord-017142-vx3rgs4r	23	6	side	side	NN
cord-017142-vx3rgs4r	23	7	effects	effect	NNS
cord-017142-vx3rgs4r	23	8	of	of	IN
cord-017142-vx3rgs4r	23	9	present	present	JJ
cord-017142-vx3rgs4r	23	10	-	-	HYPH
cord-017142-vx3rgs4r	23	11	day	day	NN
cord-017142-vx3rgs4r	23	12	novel	novel	NN
cord-017142-vx3rgs4r	23	13	regimens	regimen	NNS
cord-017142-vx3rgs4r	23	14	is	be	VBZ
cord-017142-vx3rgs4r	23	15	therefore	therefore	RB
cord-017142-vx3rgs4r	23	16	a	a	DT
cord-017142-vx3rgs4r	23	17	cornerstone	cornerstone	NN
cord-017142-vx3rgs4r	23	18	in	in	IN
cord-017142-vx3rgs4r	23	19	MM	MM	NNP
cord-017142-vx3rgs4r	23	20	care	care	NN
cord-017142-vx3rgs4r	23	21	.	.	.
cord-017142-vx3rgs4r	24	1	In	in	IN
cord-017142-vx3rgs4r	24	2	this	this	DT
cord-017142-vx3rgs4r	24	3	chapter	chapter	NN
cord-017142-vx3rgs4r	24	4	,	,	,
cord-017142-vx3rgs4r	24	5	we	-PRON-	PRP
cord-017142-vx3rgs4r	24	6	will	will	MD
cord-017142-vx3rgs4r	24	7	provide	provide	VB
cord-017142-vx3rgs4r	24	8	a	a	DT
cord-017142-vx3rgs4r	24	9	systematic	systematic	JJ
cord-017142-vx3rgs4r	24	10	review	review	NN
cord-017142-vx3rgs4r	24	11	of	of	IN
cord-017142-vx3rgs4r	24	12	the	the	DT
cord-017142-vx3rgs4r	24	13	key	key	JJ
cord-017142-vx3rgs4r	24	14	critical	critical	JJ
cord-017142-vx3rgs4r	24	15	clinical	clinical	JJ
cord-017142-vx3rgs4r	24	16	events	event	NNS
cord-017142-vx3rgs4r	24	17	which	which	WDT
cord-017142-vx3rgs4r	24	18	cause	cause	VBP
cord-017142-vx3rgs4r	24	19	medical	medical	JJ
cord-017142-vx3rgs4r	24	20	emergencies	emergency	NNS
cord-017142-vx3rgs4r	24	21	in	in	IN
cord-017142-vx3rgs4r	24	22	MM	MM	NNP
cord-017142-vx3rgs4r	24	23	.	.	.
cord-017142-vx3rgs4r	25	1	This	this	DT
cord-017142-vx3rgs4r	25	2	crucial	crucial	JJ
cord-017142-vx3rgs4r	25	3	,	,	,
cord-017142-vx3rgs4r	25	4	fundamental	fundamental	JJ
cord-017142-vx3rgs4r	25	5	knowledge	knowledge	NN
cord-017142-vx3rgs4r	25	6	for	for	IN
cord-017142-vx3rgs4r	25	7	all	all	DT
cord-017142-vx3rgs4r	25	8	clinicians	clinician	NNS
cord-017142-vx3rgs4r	25	9	who	who	WP
cord-017142-vx3rgs4r	25	10	routinely	routinely	RB
cord-017142-vx3rgs4r	25	11	care	care	VBP
cord-017142-vx3rgs4r	25	12	for	for	IN
cord-017142-vx3rgs4r	25	13	MM	MM	NNP
cord-017142-vx3rgs4r	25	14	including	include	VBG
cord-017142-vx3rgs4r	25	15	intensivists	intensivist	NNS
cord-017142-vx3rgs4r	25	16	will	will	MD
cord-017142-vx3rgs4r	25	17	allow	allow	VB
cord-017142-vx3rgs4r	25	18	for	for	IN
cord-017142-vx3rgs4r	25	19	optimal	optimal	JJ
cord-017142-vx3rgs4r	25	20	treatment	treatment	NN
cord-017142-vx3rgs4r	25	21	outcomes	outcome	NNS
cord-017142-vx3rgs4r	25	22	and	and	CC
cord-017142-vx3rgs4r	25	23	survival	survival	NN
cord-017142-vx3rgs4r	25	24	in	in	IN
cord-017142-vx3rgs4r	25	25	MM	MM	NNP
cord-017142-vx3rgs4r	25	26	.	.	.
cord-017142-vx3rgs4r	26	1	Complications	complication	NNS
cord-017142-vx3rgs4r	26	2	resulting	result	VBG
cord-017142-vx3rgs4r	26	3	from	from	IN
cord-017142-vx3rgs4r	26	4	stem	stem	NN
cord-017142-vx3rgs4r	26	5	cell	cell	NN
cord-017142-vx3rgs4r	26	6	transplant	transplant	NN
cord-017142-vx3rgs4r	26	7	or	or	CC
cord-017142-vx3rgs4r	26	8	newer	new	JJR
cord-017142-vx3rgs4r	26	9	therapies	therapy	NNS
cord-017142-vx3rgs4r	26	10	including	include	VBG
cord-017142-vx3rgs4r	26	11	chimeric	chimeric	JJ
cord-017142-vx3rgs4r	26	12	antigen	antigen	NN
cord-017142-vx3rgs4r	26	13	receptor	receptor	NN
cord-017142-vx3rgs4r	26	14	T	t	NN
cord-017142-vx3rgs4r	26	15	cell	cell	NN
cord-017142-vx3rgs4r	26	16	therapy	therapy	NN
cord-017142-vx3rgs4r	26	17	are	be	VBP
cord-017142-vx3rgs4r	26	18	beyond	beyond	IN
cord-017142-vx3rgs4r	26	19	the	the	DT
cord-017142-vx3rgs4r	26	20	scope	scope	NN
cord-017142-vx3rgs4r	26	21	of	of	IN
cord-017142-vx3rgs4r	26	22	this	this	DT
cord-017142-vx3rgs4r	26	23	review	review	NN
cord-017142-vx3rgs4r	26	24	and	and	CC
cord-017142-vx3rgs4r	26	25	will	will	MD
cord-017142-vx3rgs4r	26	26	not	not	RB
cord-017142-vx3rgs4r	26	27	be	be	VB
cord-017142-vx3rgs4r	26	28	discussed	discuss	VBN
cord-017142-vx3rgs4r	26	29	here	here	RB
cord-017142-vx3rgs4r	26	30	.	.	.
cord-017142-vx3rgs4r	27	1	Renal	renal	JJ
cord-017142-vx3rgs4r	27	2	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	27	3	in	in	IN
cord-017142-vx3rgs4r	27	4	MM	MM	NNP
cord-017142-vx3rgs4r	27	5	is	be	VBZ
cord-017142-vx3rgs4r	27	6	a	a	DT
cord-017142-vx3rgs4r	27	7	medical	medical	JJ
cord-017142-vx3rgs4r	27	8	emergency	emergency	NN
cord-017142-vx3rgs4r	27	9	that	that	WDT
cord-017142-vx3rgs4r	27	10	needs	need	VBZ
cord-017142-vx3rgs4r	27	11	immediate	immediate	JJ
cord-017142-vx3rgs4r	27	12	work	work	NN
cord-017142-vx3rgs4r	27	13	-	-	HYPH
cord-017142-vx3rgs4r	27	14	up	up	NN
cord-017142-vx3rgs4r	27	15	and	and	CC
cord-017142-vx3rgs4r	27	16	management	management	NN
cord-017142-vx3rgs4r	27	17	.	.	.
cord-017142-vx3rgs4r	28	1	There	there	EX
cord-017142-vx3rgs4r	28	2	is	be	VBZ
cord-017142-vx3rgs4r	28	3	a	a	DT
cord-017142-vx3rgs4r	28	4	wide	wide	JJ
cord-017142-vx3rgs4r	28	5	variation	variation	NN
cord-017142-vx3rgs4r	28	6	in	in	IN
cord-017142-vx3rgs4r	28	7	data	datum	NNS
cord-017142-vx3rgs4r	28	8	reporting	report	VBG
cord-017142-vx3rgs4r	28	9	on	on	IN
cord-017142-vx3rgs4r	28	10	the	the	DT
cord-017142-vx3rgs4r	28	11	incidence	incidence	NN
cord-017142-vx3rgs4r	28	12	and	and	CC
cord-017142-vx3rgs4r	28	13	the	the	DT
cord-017142-vx3rgs4r	28	14	degree	degree	NN
cord-017142-vx3rgs4r	28	15	of	of	IN
cord-017142-vx3rgs4r	28	16	renal	renal	JJ
cord-017142-vx3rgs4r	28	17	failure	failure	NN
cord-017142-vx3rgs4r	28	18	due	due	IN
cord-017142-vx3rgs4r	28	19	to	to	IN
cord-017142-vx3rgs4r	28	20	differences	difference	NNS
cord-017142-vx3rgs4r	28	21	in	in	IN
cord-017142-vx3rgs4r	28	22	the	the	DT
cord-017142-vx3rgs4r	28	23	definitions	definition	NNS
cord-017142-vx3rgs4r	28	24	of	of	IN
cord-017142-vx3rgs4r	28	25	renal	renal	JJ
cord-017142-vx3rgs4r	28	26	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	28	27	,	,	,
cord-017142-vx3rgs4r	28	28	sample	sample	NN
cord-017142-vx3rgs4r	28	29	sizes	size	NNS
cord-017142-vx3rgs4r	28	30	of	of	IN
cord-017142-vx3rgs4r	28	31	studies	study	NNS
cord-017142-vx3rgs4r	28	32	,	,	,
cord-017142-vx3rgs4r	28	33	and	and	CC
cord-017142-vx3rgs4r	28	34	populations	population	NNS
cord-017142-vx3rgs4r	28	35	assessed	assess	VBN
cord-017142-vx3rgs4r	28	36	.	.	.
cord-017142-vx3rgs4r	29	1	Renal	renal	JJ
cord-017142-vx3rgs4r	29	2	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	29	3	occurs	occur	VBZ
cord-017142-vx3rgs4r	29	4	in	in	IN
cord-017142-vx3rgs4r	29	5	more	more	JJR
cord-017142-vx3rgs4r	29	6	than	than	IN
cord-017142-vx3rgs4r	29	7	a	a	DT
cord-017142-vx3rgs4r	29	8	third	third	NN
cord-017142-vx3rgs4r	29	9	to	to	IN
cord-017142-vx3rgs4r	29	10	half	half	NN
cord-017142-vx3rgs4r	29	11	of	of	IN
cord-017142-vx3rgs4r	29	12	newly	newly	RB
cord-017142-vx3rgs4r	29	13	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	29	14	patients	patient	NNS
cord-017142-vx3rgs4r	29	15	(	(	-LRB-
cord-017142-vx3rgs4r	29	16	serum	serum	NN
cord-017142-vx3rgs4r	29	17	creatinine	creatinine	NN
cord-017142-vx3rgs4r	29	18	(	(	-LRB-
cord-017142-vx3rgs4r	29	19	sCr	scr	NN
cord-017142-vx3rgs4r	29	20	)	)	-RRB-
cord-017142-vx3rgs4r	29	21	above	above	IN
cord-017142-vx3rgs4r	29	22	the	the	DT
cord-017142-vx3rgs4r	29	23	upper	upper	JJ
cord-017142-vx3rgs4r	29	24	normal	normal	JJ
cord-017142-vx3rgs4r	29	25	limit	limit	NN
cord-017142-vx3rgs4r	29	26	or	or	CC
cord-017142-vx3rgs4r	29	27	2	2	CD
cord-017142-vx3rgs4r	29	28	mg	mg	NNP
cord-017142-vx3rgs4r	29	29	/	/	SYM
cord-017142-vx3rgs4r	29	30	dL	dl	NN
cord-017142-vx3rgs4r	29	31	or	or	CC
cord-017142-vx3rgs4r	29	32	eGFR	eGFR	VBD
cord-017142-vx3rgs4r	29	33	<	<	XX
cord-017142-vx3rgs4r	29	34	60	60	CD
cord-017142-vx3rgs4r	29	35	mL/	mL/	NNS
cord-017142-vx3rgs4r	30	1	min/1.73	min/1.73	NNP
cord-017142-vx3rgs4r	30	2	m	m	CD
cord-017142-vx3rgs4r	30	3	2	2	CD
cord-017142-vx3rgs4r	30	4	)	)	-RRB-
cord-017142-vx3rgs4r	30	5	.	.	.
cord-017142-vx3rgs4r	31	1	Table	table	NN
cord-017142-vx3rgs4r	31	2	1	1	CD
cord-017142-vx3rgs4r	31	3	details	detail	NNS
cord-017142-vx3rgs4r	32	1	the	the	DT
cord-017142-vx3rgs4r	32	2	list	list	NN
cord-017142-vx3rgs4r	32	3	of	of	IN
cord-017142-vx3rgs4r	32	4	common	common	JJ
cord-017142-vx3rgs4r	32	5	causes	cause	NNS
cord-017142-vx3rgs4r	32	6	of	of	IN
cord-017142-vx3rgs4r	32	7	renal	renal	JJ
cord-017142-vx3rgs4r	32	8	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	32	9	encountered	encounter	VBN
cord-017142-vx3rgs4r	32	10	in	in	IN
cord-017142-vx3rgs4r	32	11	clinical	clinical	JJ
cord-017142-vx3rgs4r	32	12	practice	practice	NN
cord-017142-vx3rgs4r	32	13	.	.	.
cord-017142-vx3rgs4r	33	1	As	as	IN
cord-017142-vx3rgs4r	33	2	per	per	IN
cord-017142-vx3rgs4r	33	3	the	the	DT
cord-017142-vx3rgs4r	33	4	RIFLE	rifle	NN
cord-017142-vx3rgs4r	33	5	risk	risk	NN
cord-017142-vx3rgs4r	33	6	category	category	NN
cord-017142-vx3rgs4r	33	7	,	,	,
cord-017142-vx3rgs4r	33	8	approximately	approximately	RB
cord-017142-vx3rgs4r	33	9	10	10	CD
cord-017142-vx3rgs4r	33	10	-	-	SYM
cord-017142-vx3rgs4r	33	11	15	15	CD
cord-017142-vx3rgs4r	33	12	%	%	NN
cord-017142-vx3rgs4r	33	13	of	of	IN
cord-017142-vx3rgs4r	33	14	patients	patient	NNS
cord-017142-vx3rgs4r	33	15	develop	develop	VB
cord-017142-vx3rgs4r	33	16	renal	renal	JJ
cord-017142-vx3rgs4r	33	17	failure	failure	NN
cord-017142-vx3rgs4r	33	18	,	,	,
cord-017142-vx3rgs4r	33	19	and	and	CC
cord-017142-vx3rgs4r	33	20	half	half	RB
cord-017142-vx3rgs4r	33	21	become	become	VBN
cord-017142-vx3rgs4r	33	22	dialysis	dialysis	NN
cord-017142-vx3rgs4r	33	23	dependent	dependent	JJ
cord-017142-vx3rgs4r	33	24	[	[	-LRB-
cord-017142-vx3rgs4r	33	25	9	9	CD
cord-017142-vx3rgs4r	33	26	,	,	,
cord-017142-vx3rgs4r	33	27	64	64	CD
cord-017142-vx3rgs4r	33	28	]	]	-RRB-
cord-017142-vx3rgs4r	33	29	.	.	.
cord-017142-vx3rgs4r	34	1	Even	even	RB
cord-017142-vx3rgs4r	34	2	after	after	IN
cord-017142-vx3rgs4r	34	3	an	an	DT
cord-017142-vx3rgs4r	34	4	initial	initial	JJ
cord-017142-vx3rgs4r	34	5	renal	renal	JJ
cord-017142-vx3rgs4r	34	6	recovery	recovery	NN
cord-017142-vx3rgs4r	34	7	with	with	IN
cord-017142-vx3rgs4r	34	8	appropriate	appropriate	JJ
cord-017142-vx3rgs4r	34	9	myeloma	myeloma	NN
cord-017142-vx3rgs4r	34	10	-	-	HYPH
cord-017142-vx3rgs4r	34	11	directed	direct	VBN
cord-017142-vx3rgs4r	34	12	therapy	therapy	NN
cord-017142-vx3rgs4r	34	13	,	,	,
cord-017142-vx3rgs4r	34	14	more	more	JJR
cord-017142-vx3rgs4r	34	15	than	than	IN
cord-017142-vx3rgs4r	34	16	half	half	NN
cord-017142-vx3rgs4r	34	17	of	of	IN
cord-017142-vx3rgs4r	34	18	patients	patient	NNS
cord-017142-vx3rgs4r	34	19	can	can	MD
cord-017142-vx3rgs4r	34	20	still	still	RB
cord-017142-vx3rgs4r	34	21	develop	develop	VB
cord-017142-vx3rgs4r	34	22	renal	renal	JJ
cord-017142-vx3rgs4r	34	23	failure	failure	NN
cord-017142-vx3rgs4r	34	24	during	during	IN
cord-017142-vx3rgs4r	34	25	the	the	DT
cord-017142-vx3rgs4r	34	26	disease	disease	NN
cord-017142-vx3rgs4r	34	27	course	course	NN
cord-017142-vx3rgs4r	34	28	.	.	.
cord-017142-vx3rgs4r	35	1	In	in	IN
cord-017142-vx3rgs4r	35	2	the	the	DT
cord-017142-vx3rgs4r	35	3	absence	absence	NN
cord-017142-vx3rgs4r	35	4	of	of	IN
cord-017142-vx3rgs4r	35	5	renal	renal	JJ
cord-017142-vx3rgs4r	35	6	recovery	recovery	NN
cord-017142-vx3rgs4r	35	7	,	,	,
cord-017142-vx3rgs4r	35	8	mortality	mortality	NN
cord-017142-vx3rgs4r	35	9	risk	risk	NN
cord-017142-vx3rgs4r	35	10	is	be	VBZ
cord-017142-vx3rgs4r	35	11	reported	report	VBN
cord-017142-vx3rgs4r	35	12	to	to	TO
cord-017142-vx3rgs4r	35	13	be	be	VB
cord-017142-vx3rgs4r	35	14	higher	high	JJR
cord-017142-vx3rgs4r	35	15	in	in	IN
cord-017142-vx3rgs4r	35	16	this	this	DT
cord-017142-vx3rgs4r	35	17	population	population	NN
cord-017142-vx3rgs4r	35	18	with	with	IN
cord-017142-vx3rgs4r	35	19	shortened	shorten	VBN
cord-017142-vx3rgs4r	35	20	overall	overall	JJ
cord-017142-vx3rgs4r	35	21	survival	survival	NN
cord-017142-vx3rgs4r	35	22	.	.	.
cord-017142-vx3rgs4r	36	1	With	with	IN
cord-017142-vx3rgs4r	36	2	novel	novel	JJ
cord-017142-vx3rgs4r	36	3	therapies	therapy	NNS
cord-017142-vx3rgs4r	36	4	in	in	IN
cord-017142-vx3rgs4r	36	5	myeloma	myeloma	NN
cord-017142-vx3rgs4r	36	6	,	,	,
cord-017142-vx3rgs4r	36	7	reversibility	reversibility	NN
cord-017142-vx3rgs4r	36	8	of	of	IN
cord-017142-vx3rgs4r	36	9	renal	renal	JJ
cord-017142-vx3rgs4r	36	10	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	36	11	(	(	-LRB-
cord-017142-vx3rgs4r	36	12	RI	RI	NNP
cord-017142-vx3rgs4r	36	13	)	)	-RRB-
cord-017142-vx3rgs4r	36	14	is	be	VBZ
cord-017142-vx3rgs4r	36	15	associated	associate	VBN
cord-017142-vx3rgs4r	36	16	with	with	IN
cord-017142-vx3rgs4r	36	17	improved	improved	JJ
cord-017142-vx3rgs4r	36	18	survival	survival	NN
cord-017142-vx3rgs4r	36	19	with	with	IN
cord-017142-vx3rgs4r	36	20	some	some	DT
cord-017142-vx3rgs4r	36	21	studies	study	NNS
cord-017142-vx3rgs4r	36	22	demonstrating	demonstrate	VBG
cord-017142-vx3rgs4r	36	23	similar	similar	JJ
cord-017142-vx3rgs4r	36	24	survival	survival	NN
cord-017142-vx3rgs4r	36	25	in	in	IN
cord-017142-vx3rgs4r	36	26	patients	patient	NNS
cord-017142-vx3rgs4r	36	27	who	who	WP
cord-017142-vx3rgs4r	36	28	recover	recover	VBP
cord-017142-vx3rgs4r	36	29	from	from	IN
cord-017142-vx3rgs4r	36	30	acute	acute	JJ
cord-017142-vx3rgs4r	36	31	kidney	kidney	NN
cord-017142-vx3rgs4r	36	32	injury	injury	NN
cord-017142-vx3rgs4r	36	33	(	(	-LRB-
cord-017142-vx3rgs4r	36	34	AKI	AKI	NNP
cord-017142-vx3rgs4r	36	35	)	)	-RRB-
cord-017142-vx3rgs4r	36	36	and	and	CC
cord-017142-vx3rgs4r	36	37	those	those	DT
cord-017142-vx3rgs4r	36	38	without	without	IN
cord-017142-vx3rgs4r	36	39	renal	renal	JJ
cord-017142-vx3rgs4r	36	40	impairment	impairment	NN
cord-017142-vx3rgs4r	36	41	.	.	.
cord-017142-vx3rgs4r	37	1	Therefore	therefore	RB
cord-017142-vx3rgs4r	37	2	,	,	,
cord-017142-vx3rgs4r	37	3	achieving	achieve	VBG
cord-017142-vx3rgs4r	37	4	renal	renal	JJ
cord-017142-vx3rgs4r	37	5	recovery	recovery	NN
cord-017142-vx3rgs4r	37	6	is	be	VBZ
cord-017142-vx3rgs4r	37	7	of	of	IN
cord-017142-vx3rgs4r	37	8	priority	priority	NN
cord-017142-vx3rgs4r	37	9	and	and	CC
cord-017142-vx3rgs4r	37	10	the	the	DT
cord-017142-vx3rgs4r	37	11	main	main	JJ
cord-017142-vx3rgs4r	37	12	goal	goal	NN
cord-017142-vx3rgs4r	37	13	in	in	IN
cord-017142-vx3rgs4r	37	14	these	these	DT
cord-017142-vx3rgs4r	37	15	patients	patient	NNS
cord-017142-vx3rgs4r	37	16	[	[	-LRB-
cord-017142-vx3rgs4r	37	17	1	1	CD
cord-017142-vx3rgs4r	37	18	,	,	,
cord-017142-vx3rgs4r	37	19	11	11	CD
cord-017142-vx3rgs4r	37	20	,	,	,
cord-017142-vx3rgs4r	37	21	29	29	CD
cord-017142-vx3rgs4r	37	22	,	,	,
cord-017142-vx3rgs4r	37	23	43	43	CD
cord-017142-vx3rgs4r	37	24	,	,	,
cord-017142-vx3rgs4r	37	25	125	125	CD
cord-017142-vx3rgs4r	37	26	]	]	-RRB-
cord-017142-vx3rgs4r	37	27	.	.	.
cord-017142-vx3rgs4r	38	1	MM	MM	NNP
cord-017142-vx3rgs4r	38	2	kidney	kidney	NN
cord-017142-vx3rgs4r	38	3	:	:	:
cord-017142-vx3rgs4r	38	4	In	in	IN
cord-017142-vx3rgs4r	38	5	many	many	JJ
cord-017142-vx3rgs4r	38	6	cases	case	NNS
cord-017142-vx3rgs4r	38	7	(	(	-LRB-
cord-017142-vx3rgs4r	38	8	approximately	approximately	RB
cord-017142-vx3rgs4r	38	9	40	40	CD
cord-017142-vx3rgs4r	38	10	-	-	SYM
cord-017142-vx3rgs4r	38	11	50	50	CD
cord-017142-vx3rgs4r	38	12	%	%	NN
cord-017142-vx3rgs4r	38	13	of	of	IN
cord-017142-vx3rgs4r	38	14	cases	case	NNS
cord-017142-vx3rgs4r	38	15	)	)	-RRB-
cord-017142-vx3rgs4r	38	16	,	,	,
cord-017142-vx3rgs4r	38	17	renal	renal	JJ
cord-017142-vx3rgs4r	38	18	damage	damage	NN
cord-017142-vx3rgs4r	38	19	is	be	VBZ
cord-017142-vx3rgs4r	38	20	caused	cause	VBN
cord-017142-vx3rgs4r	38	21	by	by	IN
cord-017142-vx3rgs4r	38	22	the	the	DT
cord-017142-vx3rgs4r	38	23	disproportionate	disproportionate	JJ
cord-017142-vx3rgs4r	38	24	free	free	JJ
cord-017142-vx3rgs4r	38	25	light	light	JJ
cord-017142-vx3rgs4r	38	26	chain	chain	NN
cord-017142-vx3rgs4r	38	27	(	(	-LRB-
cord-017142-vx3rgs4r	38	28	FLC	FLC	NNP
cord-017142-vx3rgs4r	38	29	)	)	-RRB-
cord-017142-vx3rgs4r	38	30	excretion	excretion	NN
cord-017142-vx3rgs4r	38	31	through	through	IN
cord-017142-vx3rgs4r	38	32	kidney	kidney	NN
cord-017142-vx3rgs4r	38	33	glomeruli	glomerulus	NNS
cord-017142-vx3rgs4r	38	34	,	,	,
cord-017142-vx3rgs4r	38	35	buildup	buildup	NN
cord-017142-vx3rgs4r	38	36	of	of	IN
cord-017142-vx3rgs4r	38	37	light	light	JJ
cord-017142-vx3rgs4r	38	38	chains	chain	NNS
cord-017142-vx3rgs4r	38	39	in	in	IN
cord-017142-vx3rgs4r	38	40	distal	distal	JJ
cord-017142-vx3rgs4r	38	41	tubules	tubule	NNS
cord-017142-vx3rgs4r	38	42	,	,	,
cord-017142-vx3rgs4r	38	43	and	and	CC
cord-017142-vx3rgs4r	38	44	cast	cast	NN
cord-017142-vx3rgs4r	38	45	formation	formation	NN
cord-017142-vx3rgs4r	38	46	which	which	WDT
cord-017142-vx3rgs4r	38	47	further	further	RB
cord-017142-vx3rgs4r	38	48	leads	lead	VBZ
cord-017142-vx3rgs4r	38	49	to	to	IN
cord-017142-vx3rgs4r	38	50	renal	renal	JJ
cord-017142-vx3rgs4r	38	51	tubular	tubular	JJ
cord-017142-vx3rgs4r	38	52	obstruction	obstruction	NN
cord-017142-vx3rgs4r	38	53	,	,	,
cord-017142-vx3rgs4r	38	54	an	an	DT
cord-017142-vx3rgs4r	38	55	entity	entity	NN
cord-017142-vx3rgs4r	38	56	referred	refer	VBN
cord-017142-vx3rgs4r	38	57	to	to	IN
cord-017142-vx3rgs4r	38	58	as	as	IN
cord-017142-vx3rgs4r	38	59	MM	MM	NNP
cord-017142-vx3rgs4r	38	60	kidney	kidney	NN
cord-017142-vx3rgs4r	38	61	.	.	.
cord-017142-vx3rgs4r	39	1	The	the	DT
cord-017142-vx3rgs4r	39	2	tubules	tubule	NNS
cord-017142-vx3rgs4r	39	3	eventually	eventually	RB
cord-017142-vx3rgs4r	39	4	rupture	rupture	VBP
cord-017142-vx3rgs4r	39	5	and	and	CC
cord-017142-vx3rgs4r	39	6	FLC	FLC	NNP
cord-017142-vx3rgs4r	39	7	extravasates	extravasate	NNS
cord-017142-vx3rgs4r	39	8	,	,	,
cord-017142-vx3rgs4r	39	9	causing	cause	VBG
cord-017142-vx3rgs4r	39	10	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	39	11	inflammation	inflammation	NN
cord-017142-vx3rgs4r	39	12	and	and	CC
cord-017142-vx3rgs4r	39	13	damage	damage	NN
cord-017142-vx3rgs4r	39	14	.	.	.
cord-017142-vx3rgs4r	40	1	This	this	DT
cord-017142-vx3rgs4r	40	2	is	be	VBZ
cord-017142-vx3rgs4r	40	3	usually	usually	RB
cord-017142-vx3rgs4r	40	4	compounded	compound	VBN
cord-017142-vx3rgs4r	40	5	by	by	IN
cord-017142-vx3rgs4r	40	6	renal	renal	JJ
cord-017142-vx3rgs4r	40	7	injury	injury	NN
cord-017142-vx3rgs4r	40	8	from	from	IN
cord-017142-vx3rgs4r	40	9	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	40	10	,	,	,
cord-017142-vx3rgs4r	40	11	dehydration	dehydration	NN
cord-017142-vx3rgs4r	40	12	,	,	,
cord-017142-vx3rgs4r	40	13	poor	poor	JJ
cord-017142-vx3rgs4r	40	14	intake	intake	NN
cord-017142-vx3rgs4r	40	15	,	,	,
cord-017142-vx3rgs4r	40	16	use	use	NN
cord-017142-vx3rgs4r	40	17	of	of	IN
cord-017142-vx3rgs4r	40	18	nephrotoxic	nephrotoxic	FW
cord-017142-vx3rgs4r	40	19	analgesics	analgesic	NNS
cord-017142-vx3rgs4r	40	20	,	,	,
cord-017142-vx3rgs4r	40	21	IV	IV	NNP
cord-017142-vx3rgs4r	40	22	contrast	contrast	NN
cord-017142-vx3rgs4r	40	23	,	,	,
cord-017142-vx3rgs4r	40	24	use	use	NN
cord-017142-vx3rgs4r	40	25	of	of	IN
cord-017142-vx3rgs4r	40	26	ACE	ACE	NNP
cord-017142-vx3rgs4r	40	27	/	/	SYM
cord-017142-vx3rgs4r	40	28	ARB	ARB	NNP
cord-017142-vx3rgs4r	40	29	blockade	blockade	NN
cord-017142-vx3rgs4r	40	30	,	,	,
cord-017142-vx3rgs4r	40	31	underlying	underlie	VBG
cord-017142-vx3rgs4r	40	32	chronic	chronic	JJ
cord-017142-vx3rgs4r	40	33	kidney	kidney	NN
cord-017142-vx3rgs4r	40	34	disorder	disorder	NN
cord-017142-vx3rgs4r	40	35	,	,	,
cord-017142-vx3rgs4r	40	36	and/or	and/or	CC
cord-017142-vx3rgs4r	40	37	underlying	underlie	VBG
cord-017142-vx3rgs4r	40	38	infection	infection	NN
cord-017142-vx3rgs4r	40	39	.	.	.
cord-017142-vx3rgs4r	41	1	Early	early	JJ
cord-017142-vx3rgs4r	41	2	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	41	3	and	and	CC
cord-017142-vx3rgs4r	41	4	timely	timely	JJ
cord-017142-vx3rgs4r	41	5	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	41	6	intervention	intervention	NN
cord-017142-vx3rgs4r	41	7	at	at	IN
cord-017142-vx3rgs4r	41	8	the	the	DT
cord-017142-vx3rgs4r	41	9	time	time	NN
cord-017142-vx3rgs4r	41	10	of	of	IN
cord-017142-vx3rgs4r	41	11	presentation	presentation	NN
cord-017142-vx3rgs4r	41	12	to	to	IN
cord-017142-vx3rgs4r	41	13	the	the	DT
cord-017142-vx3rgs4r	41	14	emergency	emergency	NN
cord-017142-vx3rgs4r	41	15	center	center	NN
cord-017142-vx3rgs4r	41	16	are	be	VBP
cord-017142-vx3rgs4r	41	17	critical	critical	JJ
cord-017142-vx3rgs4r	41	18	.	.	.
cord-017142-vx3rgs4r	42	1	Therapy	therapy	NN
cord-017142-vx3rgs4r	42	2	should	should	MD
cord-017142-vx3rgs4r	42	3	include	include	VB
cord-017142-vx3rgs4r	42	4	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	42	5	resuscitation	resuscitation	NN
cord-017142-vx3rgs4r	42	6	with	with	IN
cord-017142-vx3rgs4r	42	7	IV	IV	NNP
cord-017142-vx3rgs4r	42	8	fluids	fluid	NNS
cord-017142-vx3rgs4r	42	9	in	in	IN
cord-017142-vx3rgs4r	42	10	efforts	effort	NNS
cord-017142-vx3rgs4r	42	11	to	to	TO
cord-017142-vx3rgs4r	42	12	maintain	maintain	VB
cord-017142-vx3rgs4r	42	13	normal	normal	JJ
cord-017142-vx3rgs4r	42	14	urine	urine	NN
cord-017142-vx3rgs4r	42	15	output	output	NN
cord-017142-vx3rgs4r	42	16	,	,	,
cord-017142-vx3rgs4r	42	17	treating	treat	VBG
cord-017142-vx3rgs4r	42	18	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	42	19	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	42	20	and	and	CC
cord-017142-vx3rgs4r	42	21	other	other	JJ
cord-017142-vx3rgs4r	42	22	electrolyte	electrolyte	JJ
cord-017142-vx3rgs4r	42	23	imbalances	imbalance	NNS
cord-017142-vx3rgs4r	42	24	,	,	,
cord-017142-vx3rgs4r	42	25	initiating	initiate	VBG
cord-017142-vx3rgs4r	42	26	treatment	treatment	NN
cord-017142-vx3rgs4r	42	27	of	of	IN
cord-017142-vx3rgs4r	42	28	underlying	underlie	VBG
cord-017142-vx3rgs4r	42	29	infection	infection	NN
cord-017142-vx3rgs4r	42	30	,	,	,
cord-017142-vx3rgs4r	42	31	and	and	CC
cord-017142-vx3rgs4r	42	32	avoiding	avoid	VBG
cord-017142-vx3rgs4r	42	33	nephrotoxins	nephrotoxin	NNS
cord-017142-vx3rgs4r	42	34	.	.	.
cord-017142-vx3rgs4r	43	1	A	a	DT
cord-017142-vx3rgs4r	43	2	multidisciplinary	multidisciplinary	JJ
cord-017142-vx3rgs4r	43	3	approach	approach	NN
cord-017142-vx3rgs4r	43	4	with	with	IN
cord-017142-vx3rgs4r	43	5	hematology	hematology	NN
cord-017142-vx3rgs4r	43	6	and	and	CC
cord-017142-vx3rgs4r	43	7	nephrology	nephrology	NN
cord-017142-vx3rgs4r	43	8	consults	consult	VBZ
cord-017142-vx3rgs4r	43	9	is	be	VBZ
cord-017142-vx3rgs4r	43	10	paramount	paramount	NN
cord-017142-vx3rgs4r	43	11	to	to	TO
cord-017142-vx3rgs4r	43	12	optimize	optimize	VB
cord-017142-vx3rgs4r	43	13	care	care	NN
cord-017142-vx3rgs4r	43	14	in	in	IN
cord-017142-vx3rgs4r	43	15	these	these	DT
cord-017142-vx3rgs4r	43	16	patients	patient	NNS
cord-017142-vx3rgs4r	43	17	.	.	.
cord-017142-vx3rgs4r	44	1	Suspicion	suspicion	NN
cord-017142-vx3rgs4r	44	2	of	of	IN
cord-017142-vx3rgs4r	44	3	cast	cast	NN
cord-017142-vx3rgs4r	44	4	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	44	5	in	in	IN
cord-017142-vx3rgs4r	44	6	newly	newly	RB
cord-017142-vx3rgs4r	44	7	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	44	8	myeloma	myeloma	NN
cord-017142-vx3rgs4r	44	9	patients	patient	NNS
cord-017142-vx3rgs4r	44	10	with	with	IN
cord-017142-vx3rgs4r	44	11	serum	serum	NN
cord-017142-vx3rgs4r	44	12	FLC	FLC	NNP
cord-017142-vx3rgs4r	44	13	above	above	IN
cord-017142-vx3rgs4r	44	14	1000	1000	CD
cord-017142-vx3rgs4r	44	15	mg	mg	NNP
cord-017142-vx3rgs4r	44	16	/	/	SYM
cord-017142-vx3rgs4r	44	17	L	L	NNP
cord-017142-vx3rgs4r	44	18	should	should	MD
cord-017142-vx3rgs4r	44	19	be	be	VB
cord-017142-vx3rgs4r	44	20	high	high	JJ
cord-017142-vx3rgs4r	44	21	,	,	,
cord-017142-vx3rgs4r	44	22	especially	especially	RB
cord-017142-vx3rgs4r	44	23	if	if	IN
cord-017142-vx3rgs4r	44	24	associated	associate	VBN
cord-017142-vx3rgs4r	44	25	selective	selective	JJ
cord-017142-vx3rgs4r	44	26	proteinuria	proteinuria	NN
cord-017142-vx3rgs4r	44	27	composed	compose	VBN
cord-017142-vx3rgs4r	44	28	of	of	IN
cord-017142-vx3rgs4r	44	29	FLC	FLC	NNP
cord-017142-vx3rgs4r	44	30	/	/	SYM
cord-017142-vx3rgs4r	44	31	BJP	BJP	NNP
cord-017142-vx3rgs4r	44	32	exists	exist	VBZ
cord-017142-vx3rgs4r	44	33	,	,	,
cord-017142-vx3rgs4r	44	34	as	as	IN
cord-017142-vx3rgs4r	44	35	the	the	DT
cord-017142-vx3rgs4r	44	36	degree	degree	NN
cord-017142-vx3rgs4r	44	37	of	of	IN
cord-017142-vx3rgs4r	44	38	renal	renal	JJ
cord-017142-vx3rgs4r	44	39	injury	injury	NN
cord-017142-vx3rgs4r	44	40	is	be	VBZ
cord-017142-vx3rgs4r	44	41	usually	usually	RB
cord-017142-vx3rgs4r	44	42	related	relate	VBN
cord-017142-vx3rgs4r	44	43	to	to	IN
cord-017142-vx3rgs4r	44	44	tumor	tumor	NN
cord-017142-vx3rgs4r	44	45	load	load	NN
cord-017142-vx3rgs4r	44	46	[	[	-LRB-
cord-017142-vx3rgs4r	44	47	55	55	CD
cord-017142-vx3rgs4r	44	48	]	]	-RRB-
cord-017142-vx3rgs4r	44	49	.	.	.
cord-017142-vx3rgs4r	45	1	A	a	DT
cord-017142-vx3rgs4r	45	2	percutaneous	percutaneous	JJ
cord-017142-vx3rgs4r	45	3	kidney	kidney	NN
cord-017142-vx3rgs4r	45	4	biopsy	biopsy	NN
cord-017142-vx3rgs4r	45	5	with	with	IN
cord-017142-vx3rgs4r	45	6	histology	histology	NN
cord-017142-vx3rgs4r	45	7	is	be	VBZ
cord-017142-vx3rgs4r	45	8	not	not	RB
cord-017142-vx3rgs4r	45	9	required	require	VBN
cord-017142-vx3rgs4r	45	10	to	to	TO
cord-017142-vx3rgs4r	45	11	initiate	initiate	VB
cord-017142-vx3rgs4r	45	12	treatment	treatment	NN
cord-017142-vx3rgs4r	45	13	if	if	IN
cord-017142-vx3rgs4r	45	14	myeloma	myeloma	NN
cord-017142-vx3rgs4r	45	15	has	have	VBZ
cord-017142-vx3rgs4r	45	16	been	be	VBN
cord-017142-vx3rgs4r	45	17	confirmed	confirm	VBN
cord-017142-vx3rgs4r	45	18	but	but	CC
cord-017142-vx3rgs4r	45	19	can	can	MD
cord-017142-vx3rgs4r	45	20	be	be	VB
cord-017142-vx3rgs4r	45	21	helpful	helpful	JJ
cord-017142-vx3rgs4r	45	22	to	to	TO
cord-017142-vx3rgs4r	45	23	confirm	confirm	VB
cord-017142-vx3rgs4r	45	24	the	the	DT
cord-017142-vx3rgs4r	45	25	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	45	26	,	,	,
cord-017142-vx3rgs4r	45	27	assess	assess	VB
cord-017142-vx3rgs4r	45	28	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	45	29	light	light	JJ
cord-017142-vx3rgs4r	45	30	chain	chain	NN
cord-017142-vx3rgs4r	45	31	or	or	CC
cord-017142-vx3rgs4r	45	32	amyloid	amyloid	NN
cord-017142-vx3rgs4r	45	33	deposition	deposition	NN
cord-017142-vx3rgs4r	45	34	disease	disease	NN
cord-017142-vx3rgs4r	45	35	,	,	,
cord-017142-vx3rgs4r	45	36	and	and	CC
cord-017142-vx3rgs4r	45	37	predict	predict	VB
cord-017142-vx3rgs4r	45	38	prognosis	prognosis	NN
cord-017142-vx3rgs4r	45	39	.	.	.
cord-017142-vx3rgs4r	46	1	The	the	DT
cord-017142-vx3rgs4r	46	2	need	need	NN
cord-017142-vx3rgs4r	46	3	for	for	IN
cord-017142-vx3rgs4r	46	4	a	a	DT
cord-017142-vx3rgs4r	46	5	renal	renal	JJ
cord-017142-vx3rgs4r	46	6	biopsy	biopsy	NN
cord-017142-vx3rgs4r	46	7	should	should	MD
cord-017142-vx3rgs4r	46	8	be	be	VB
cord-017142-vx3rgs4r	46	9	discussed	discuss	VBN
cord-017142-vx3rgs4r	46	10	for	for	IN
cord-017142-vx3rgs4r	46	11	patients	patient	NNS
cord-017142-vx3rgs4r	46	12	with	with	IN
cord-017142-vx3rgs4r	46	13	lower	low	JJR
cord-017142-vx3rgs4r	46	14	levels	level	NNS
cord-017142-vx3rgs4r	46	15	of	of	IN
cord-017142-vx3rgs4r	46	16	toxic	toxic	JJ
cord-017142-vx3rgs4r	46	17	FLC	FLC	NNP
cord-017142-vx3rgs4r	46	18	,	,	,
cord-017142-vx3rgs4r	46	19	as	as	IN
cord-017142-vx3rgs4r	46	20	these	these	DT
cord-017142-vx3rgs4r	46	21	patients	patient	NNS
cord-017142-vx3rgs4r	46	22	are	be	VBP
cord-017142-vx3rgs4r	46	23	more	more	RBR
cord-017142-vx3rgs4r	46	24	likely	likely	JJ
cord-017142-vx3rgs4r	46	25	to	to	TO
cord-017142-vx3rgs4r	46	26	have	have	VB
cord-017142-vx3rgs4r	46	27	alternate	alternate	JJ
cord-017142-vx3rgs4r	46	28	etiologies	etiology	NNS
cord-017142-vx3rgs4r	46	29	for	for	IN
cord-017142-vx3rgs4r	46	30	their	-PRON-	PRP$
cord-017142-vx3rgs4r	46	31	RI	RI	NNP
cord-017142-vx3rgs4r	46	32	.	.	.
cord-017142-vx3rgs4r	47	1	In	in	IN
cord-017142-vx3rgs4r	47	2	patients	patient	NNS
cord-017142-vx3rgs4r	47	3	with	with	IN
cord-017142-vx3rgs4r	47	4	significant	significant	JJ
cord-017142-vx3rgs4r	47	5	light	light	JJ
cord-017142-vx3rgs4r	47	6	chain	chain	NN
cord-017142-vx3rgs4r	47	7	burden	burden	NN
cord-017142-vx3rgs4r	47	8	,	,	,
cord-017142-vx3rgs4r	47	9	it	-PRON-	PRP
cord-017142-vx3rgs4r	47	10	is	be	VBZ
cord-017142-vx3rgs4r	47	11	critical	critical	JJ
cord-017142-vx3rgs4r	47	12	to	to	TO
cord-017142-vx3rgs4r	47	13	begin	begin	VB
cord-017142-vx3rgs4r	47	14	treatment	treatment	NN
cord-017142-vx3rgs4r	47	15	immediately	immediately	RB
cord-017142-vx3rgs4r	47	16	with	with	IN
cord-017142-vx3rgs4r	47	17	renal	renal	JJ
cord-017142-vx3rgs4r	47	18	recovery	recovery	NN
cord-017142-vx3rgs4r	47	19	as	as	IN
cord-017142-vx3rgs4r	47	20	the	the	DT
cord-017142-vx3rgs4r	47	21	major	major	JJ
cord-017142-vx3rgs4r	47	22	immediate	immediate	JJ
cord-017142-vx3rgs4r	47	23	goal	goal	NN
cord-017142-vx3rgs4r	47	24	.	.	.
cord-017142-vx3rgs4r	48	1	The	the	DT
cord-017142-vx3rgs4r	48	2	only	only	JJ
cord-017142-vx3rgs4r	48	3	proven	prove	VBN
cord-017142-vx3rgs4r	48	4	modality	modality	NN
cord-017142-vx3rgs4r	48	5	with	with	IN
cord-017142-vx3rgs4r	48	6	the	the	DT
cord-017142-vx3rgs4r	48	7	best	good	JJS
cord-017142-vx3rgs4r	48	8	chance	chance	NN
cord-017142-vx3rgs4r	48	9	of	of	IN
cord-017142-vx3rgs4r	48	10	renal	renal	JJ
cord-017142-vx3rgs4r	48	11	recovery	recovery	NN
cord-017142-vx3rgs4r	48	12	is	be	VBZ
cord-017142-vx3rgs4r	48	13	rapid	rapid	JJ
cord-017142-vx3rgs4r	48	14	cytoreduction	cytoreduction	NN
cord-017142-vx3rgs4r	48	15	to	to	TO
cord-017142-vx3rgs4r	48	16	decrease	decrease	VB
cord-017142-vx3rgs4r	48	17	light	light	JJ
cord-017142-vx3rgs4r	48	18	chain	chain	NN
cord-017142-vx3rgs4r	48	19	production	production	NN
cord-017142-vx3rgs4r	48	20	.	.	.
cord-017142-vx3rgs4r	49	1	Newer	new	JJR
cord-017142-vx3rgs4r	49	2	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	49	3	agents	agent	NNS
cord-017142-vx3rgs4r	49	4	lower	low	JJR
cord-017142-vx3rgs4r	49	5	FLCs	flc	NNS
cord-017142-vx3rgs4r	49	6	quickly	quickly	RB
cord-017142-vx3rgs4r	49	7	,	,	,
cord-017142-vx3rgs4r	49	8	especially	especially	RB
cord-017142-vx3rgs4r	49	9	with	with	IN
cord-017142-vx3rgs4r	49	10	a	a	DT
cord-017142-vx3rgs4r	49	11	combinatorial	combinatorial	JJ
cord-017142-vx3rgs4r	49	12	approach	approach	NN
cord-017142-vx3rgs4r	49	13	.	.	.
cord-017142-vx3rgs4r	50	1	Many	many	JJ
cord-017142-vx3rgs4r	50	2	clinical	clinical	JJ
cord-017142-vx3rgs4r	50	3	trials	trial	NNS
cord-017142-vx3rgs4r	50	4	have	have	VBP
cord-017142-vx3rgs4r	50	5	shown	show	VBN
cord-017142-vx3rgs4r	50	6	that	that	IN
cord-017142-vx3rgs4r	50	7	a	a	DT
cord-017142-vx3rgs4r	50	8	bortezomib	bortezomib	NN
cord-017142-vx3rgs4r	50	9	-	-	HYPH
cord-017142-vx3rgs4r	50	10	dexamethasone	dexamethasone	VBN
cord-017142-vx3rgs4r	50	11	combination	combination	NN
cord-017142-vx3rgs4r	50	12	regimen	regimen	NN
cord-017142-vx3rgs4r	50	13	achieves	achieve	VBZ
cord-017142-vx3rgs4r	50	14	this	this	DT
cord-017142-vx3rgs4r	50	15	goal	goal	NN
cord-017142-vx3rgs4r	50	16	[	[	-LRB-
cord-017142-vx3rgs4r	50	17	30	30	CD
cord-017142-vx3rgs4r	50	18	]	]	-RRB-
cord-017142-vx3rgs4r	50	19	.	.	.
cord-017142-vx3rgs4r	51	1	Attaining	attain	VBG
cord-017142-vx3rgs4r	51	2	a	a	DT
cord-017142-vx3rgs4r	51	3	pre	pre	JJ
cord-017142-vx3rgs4r	51	4	-	-	JJ
cord-017142-vx3rgs4r	51	5	dialysis	dialysis	JJ
cord-017142-vx3rgs4r	51	6	serum	serum	NN
cord-017142-vx3rgs4r	51	7	-	-	HYPH
cord-017142-vx3rgs4r	51	8	free	free	JJ
cord-017142-vx3rgs4r	51	9	light	light	JJ
cord-017142-vx3rgs4r	51	10	chain	chain	NN
cord-017142-vx3rgs4r	51	11	level	level	NN
cord-017142-vx3rgs4r	51	12	below	below	IN
cord-017142-vx3rgs4r	51	13	500	500	CD
cord-017142-vx3rgs4r	51	14	mg	mg	NNP
cord-017142-vx3rgs4r	51	15	/	/	SYM
cord-017142-vx3rgs4r	51	16	L	L	NNP
cord-017142-vx3rgs4r	51	17	and	and	CC
cord-017142-vx3rgs4r	51	18	a	a	DT
cord-017142-vx3rgs4r	51	19	60	60	CD
cord-017142-vx3rgs4r	51	20	%	%	NN
cord-017142-vx3rgs4r	51	21	reduction	reduction	NN
cord-017142-vx3rgs4r	51	22	after	after	IN
cord-017142-vx3rgs4r	51	23	the	the	DT
cord-017142-vx3rgs4r	51	24	first	first	JJ
cord-017142-vx3rgs4r	51	25	cycle	cycle	NN
cord-017142-vx3rgs4r	51	26	of	of	IN
cord-017142-vx3rgs4r	51	27	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	51	28	are	be	VBP
cord-017142-vx3rgs4r	51	29	independent	independent	JJ
cord-017142-vx3rgs4r	51	30	predictive	predictive	JJ
cord-017142-vx3rgs4r	51	31	factors	factor	NNS
cord-017142-vx3rgs4r	51	32	of	of	IN
cord-017142-vx3rgs4r	51	33	renal	renal	JJ
cord-017142-vx3rgs4r	51	34	recovery	recovery	NN
cord-017142-vx3rgs4r	51	35	and	and	CC
cord-017142-vx3rgs4r	51	36	hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	51	37	independence	independence	NN
cord-017142-vx3rgs4r	51	38	at	at	IN
cord-017142-vx3rgs4r	51	39	1	1	CD
cord-017142-vx3rgs4r	51	40	year	year	NN
cord-017142-vx3rgs4r	51	41	[	[	-LRB-
cord-017142-vx3rgs4r	51	42	56	56	CD
cord-017142-vx3rgs4r	51	43	,	,	,
cord-017142-vx3rgs4r	51	44	57	57	CD
cord-017142-vx3rgs4r	51	45	]	]	-RRB-
cord-017142-vx3rgs4r	51	46	.	.	.
cord-017142-vx3rgs4r	52	1	Hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	52	2	or	or	CC
cord-017142-vx3rgs4r	52	3	TPE	tpe	NN
cord-017142-vx3rgs4r	52	4	for	for	IN
cord-017142-vx3rgs4r	52	5	the	the	DT
cord-017142-vx3rgs4r	52	6	sole	sole	JJ
cord-017142-vx3rgs4r	52	7	purpose	purpose	NN
cord-017142-vx3rgs4r	52	8	of	of	IN
cord-017142-vx3rgs4r	52	9	offloading	offload	VBG
cord-017142-vx3rgs4r	52	10	tumor	tumor	NN
cord-017142-vx3rgs4r	52	11	burden	burden	NN
cord-017142-vx3rgs4r	52	12	is	be	VBZ
cord-017142-vx3rgs4r	52	13	currently	currently	RB
cord-017142-vx3rgs4r	52	14	investigational	investigational	JJ
cord-017142-vx3rgs4r	52	15	,	,	,
cord-017142-vx3rgs4r	52	16	as	as	IN
cord-017142-vx3rgs4r	52	17	none	none	NN
cord-017142-vx3rgs4r	52	18	of	of	IN
cord-017142-vx3rgs4r	52	19	the	the	DT
cord-017142-vx3rgs4r	52	20	randomized	randomized	JJ
cord-017142-vx3rgs4r	52	21	trials	trial	NNS
cord-017142-vx3rgs4r	52	22	have	have	VBP
cord-017142-vx3rgs4r	52	23	shown	show	VBN
cord-017142-vx3rgs4r	52	24	a	a	DT
cord-017142-vx3rgs4r	52	25	significant	significant	JJ
cord-017142-vx3rgs4r	52	26	benefit	benefit	NN
cord-017142-vx3rgs4r	52	27	.	.	.
cord-017142-vx3rgs4r	53	1	Though	though	IN
cord-017142-vx3rgs4r	53	2	it	-PRON-	PRP
cord-017142-vx3rgs4r	53	3	takes	take	VBZ
cord-017142-vx3rgs4r	53	4	a	a	DT
cord-017142-vx3rgs4r	53	5	few	few	JJ
cord-017142-vx3rgs4r	53	6	days	day	NNS
cord-017142-vx3rgs4r	53	7	to	to	IN
cord-017142-vx3rgs4r	53	8	weeks	week	NNS
cord-017142-vx3rgs4r	53	9	to	to	TO
cord-017142-vx3rgs4r	53	10	observe	observe	VB
cord-017142-vx3rgs4r	53	11	the	the	DT
cord-017142-vx3rgs4r	53	12	impact	impact	NN
cord-017142-vx3rgs4r	53	13	of	of	IN
cord-017142-vx3rgs4r	53	14	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	53	15	on	on	IN
cord-017142-vx3rgs4r	53	16	light	light	JJ
cord-017142-vx3rgs4r	53	17	chain	chain	NN
cord-017142-vx3rgs4r	53	18	production	production	NN
cord-017142-vx3rgs4r	53	19	,	,	,
cord-017142-vx3rgs4r	53	20	current	current	JJ
cord-017142-vx3rgs4r	53	21	evidence	evidence	NN
cord-017142-vx3rgs4r	53	22	suggests	suggest	VBZ
cord-017142-vx3rgs4r	53	23	using	use	VBG
cord-017142-vx3rgs4r	53	24	hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	53	25	only	only	RB
cord-017142-vx3rgs4r	53	26	for	for	IN
cord-017142-vx3rgs4r	53	27	clinical	clinical	JJ
cord-017142-vx3rgs4r	53	28	indications	indication	NNS
cord-017142-vx3rgs4r	53	29	of	of	IN
cord-017142-vx3rgs4r	53	30	renal	renal	JJ
cord-017142-vx3rgs4r	53	31	replacement	replacement	NN
cord-017142-vx3rgs4r	53	32	therapy	therapy	NN
cord-017142-vx3rgs4r	53	33	which	which	WDT
cord-017142-vx3rgs4r	53	34	may	may	MD
cord-017142-vx3rgs4r	53	35	exist	exist	VB
cord-017142-vx3rgs4r	53	36	and	and	CC
cord-017142-vx3rgs4r	53	37	not	not	RB
cord-017142-vx3rgs4r	53	38	solely	solely	RB
cord-017142-vx3rgs4r	53	39	for	for	IN
cord-017142-vx3rgs4r	53	40	reduction	reduction	NN
cord-017142-vx3rgs4r	53	41	of	of	IN
cord-017142-vx3rgs4r	53	42	tumor	tumor	NN
cord-017142-vx3rgs4r	53	43	load	load	NN
cord-017142-vx3rgs4r	53	44	.	.	.
cord-017142-vx3rgs4r	54	1	Based	base	VBN
cord-017142-vx3rgs4r	54	2	on	on	IN
cord-017142-vx3rgs4r	54	3	two	two	CD
cord-017142-vx3rgs4r	54	4	randomized	randomized	JJ
cord-017142-vx3rgs4r	54	5	clinical	clinical	JJ
cord-017142-vx3rgs4r	54	6	trials	trial	NNS
cord-017142-vx3rgs4r	54	7	,	,	,
cord-017142-vx3rgs4r	54	8	the	the	DT
cord-017142-vx3rgs4r	54	9	use	use	NN
cord-017142-vx3rgs4r	54	10	of	of	IN
cord-017142-vx3rgs4r	54	11	high	high	JJ
cord-017142-vx3rgs4r	54	12	cutoff	cutoff	NN
cord-017142-vx3rgs4r	54	13	hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	54	14	to	to	TO
cord-017142-vx3rgs4r	54	15	rapidly	rapidly	RB
cord-017142-vx3rgs4r	54	16	reduce	reduce	VB
cord-017142-vx3rgs4r	54	17	the	the	DT
cord-017142-vx3rgs4r	54	18	load	load	NN
cord-017142-vx3rgs4r	54	19	of	of	IN
cord-017142-vx3rgs4r	54	20	nephrotoxic	nephrotoxic	NNP
cord-017142-vx3rgs4r	54	21	light	light	JJ
cord-017142-vx3rgs4r	54	22	chains	chain	NNS
cord-017142-vx3rgs4r	54	23	may	may	MD
cord-017142-vx3rgs4r	54	24	be	be	VB
cord-017142-vx3rgs4r	54	25	an	an	DT
cord-017142-vx3rgs4r	54	26	option	option	NN
cord-017142-vx3rgs4r	54	27	in	in	IN
cord-017142-vx3rgs4r	54	28	patients	patient	NNS
cord-017142-vx3rgs4r	54	29	requiring	require	VBG
cord-017142-vx3rgs4r	54	30	dialysis	dialysis	NN
cord-017142-vx3rgs4r	54	31	when	when	WRB
cord-017142-vx3rgs4r	54	32	treated	treat	VBN
cord-017142-vx3rgs4r	54	33	with	with	IN
cord-017142-vx3rgs4r	54	34	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	54	35	-	-	HYPH
cord-017142-vx3rgs4r	54	36	based	base	VBN
cord-017142-vx3rgs4r	54	37	therapies	therapy	NNS
cord-017142-vx3rgs4r	54	38	,	,	,
cord-017142-vx3rgs4r	54	39	but	but	CC
cord-017142-vx3rgs4r	54	40	the	the	DT
cord-017142-vx3rgs4r	54	41	results	result	NNS
cord-017142-vx3rgs4r	54	42	may	may	MD
cord-017142-vx3rgs4r	54	43	be	be	VB
cord-017142-vx3rgs4r	54	44	stochastic	stochastic	JJ
cord-017142-vx3rgs4r	54	45	at	at	IN
cord-017142-vx3rgs4r	54	46	best	well	RBS
cord-017142-vx3rgs4r	54	47	[	[	-LRB-
cord-017142-vx3rgs4r	54	48	14	14	CD
cord-017142-vx3rgs4r	54	49	,	,	,
cord-017142-vx3rgs4r	54	50	22	22	CD
cord-017142-vx3rgs4r	54	51	,	,	,
cord-017142-vx3rgs4r	54	52	108	108	CD
cord-017142-vx3rgs4r	54	53	]	]	-RRB-
cord-017142-vx3rgs4r	54	54	.	.	.
cord-017142-vx3rgs4r	55	1	TPE	TPE	NNP
cord-017142-vx3rgs4r	55	2	can	can	MD
cord-017142-vx3rgs4r	55	3	rapidly	rapidly	RB
cord-017142-vx3rgs4r	55	4	reduce	reduce	VB
cord-017142-vx3rgs4r	55	5	FLC	FLC	NNP
cord-017142-vx3rgs4r	55	6	loads	load	NNS
cord-017142-vx3rgs4r	55	7	;	;	:
cord-017142-vx3rgs4r	55	8	however	however	RB
cord-017142-vx3rgs4r	55	9	its	-PRON-	PRP$
cord-017142-vx3rgs4r	55	10	role	role	NN
cord-017142-vx3rgs4r	55	11	in	in	IN
cord-017142-vx3rgs4r	55	12	cast	cast	NN
cord-017142-vx3rgs4r	55	13	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	55	14	comes	come	VBZ
cord-017142-vx3rgs4r	55	15	from	from	IN
cord-017142-vx3rgs4r	55	16	small	small	JJ
cord-017142-vx3rgs4r	55	17	retrospective	retrospective	JJ
cord-017142-vx3rgs4r	55	18	trials	trial	NNS
cord-017142-vx3rgs4r	55	19	which	which	WDT
cord-017142-vx3rgs4r	55	20	provide	provide	VBP
cord-017142-vx3rgs4r	55	21	no	no	DT
cord-017142-vx3rgs4r	55	22	data	datum	NNS
cord-017142-vx3rgs4r	55	23	on	on	IN
cord-017142-vx3rgs4r	55	24	the	the	DT
cord-017142-vx3rgs4r	55	25	renal	renal	JJ
cord-017142-vx3rgs4r	55	26	histology	histology	NN
cord-017142-vx3rgs4r	55	27	or	or	CC
cord-017142-vx3rgs4r	55	28	SFLC	SFLC	NNP
cord-017142-vx3rgs4r	55	29	levels	level	NNS
cord-017142-vx3rgs4r	55	30	.	.	.
cord-017142-vx3rgs4r	56	1	In	in	IN
cord-017142-vx3rgs4r	56	2	studies	study	NNS
cord-017142-vx3rgs4r	56	3	that	that	WDT
cord-017142-vx3rgs4r	56	4	demonstrated	demonstrate	VBD
cord-017142-vx3rgs4r	56	5	benefit	benefit	NN
cord-017142-vx3rgs4r	56	6	,	,	,
cord-017142-vx3rgs4r	56	7	obtaining	obtain	VBG
cord-017142-vx3rgs4r	56	8	a	a	DT
cord-017142-vx3rgs4r	56	9	biopsy	biopsy	NN
cord-017142-vx3rgs4r	56	10	and	and	CC
cord-017142-vx3rgs4r	56	11	using	use	VBG
cord-017142-vx3rgs4r	56	12	a	a	DT
cord-017142-vx3rgs4r	56	13	proteasome	proteasome	VBN
cord-017142-vx3rgs4r	56	14	inhibitor	inhibitor	NN
cord-017142-vx3rgs4r	56	15	(	(	-LRB-
cord-017142-vx3rgs4r	56	16	PI)-based	pi)-based	CD
cord-017142-vx3rgs4r	56	17	treatment	treatment	NN
cord-017142-vx3rgs4r	56	18	were	be	VBD
cord-017142-vx3rgs4r	56	19	not	not	RB
cord-017142-vx3rgs4r	56	20	uniformly	uniformly	RB
cord-017142-vx3rgs4r	56	21	applied	apply	VBN
cord-017142-vx3rgs4r	56	22	,	,	,
cord-017142-vx3rgs4r	56	23	making	make	VBG
cord-017142-vx3rgs4r	56	24	interpretation	interpretation	NN
cord-017142-vx3rgs4r	56	25	of	of	IN
cord-017142-vx3rgs4r	56	26	the	the	DT
cord-017142-vx3rgs4r	56	27	data	datum	NNS
cord-017142-vx3rgs4r	56	28	difficult	difficult	JJ
cord-017142-vx3rgs4r	56	29	.	.	.
cord-017142-vx3rgs4r	57	1	Especially	especially	RB
cord-017142-vx3rgs4r	57	2	in	in	IN
cord-017142-vx3rgs4r	57	3	the	the	DT
cord-017142-vx3rgs4r	57	4	era	era	NN
cord-017142-vx3rgs4r	57	5	of	of	IN
cord-017142-vx3rgs4r	57	6	novel	novel	JJ
cord-017142-vx3rgs4r	57	7	drugs	drug	NNS
cord-017142-vx3rgs4r	57	8	,	,	,
cord-017142-vx3rgs4r	57	9	the	the	DT
cord-017142-vx3rgs4r	57	10	evidence	evidence	NN
cord-017142-vx3rgs4r	57	11	in	in	IN
cord-017142-vx3rgs4r	57	12	favor	favor	NN
cord-017142-vx3rgs4r	57	13	of	of	IN
cord-017142-vx3rgs4r	57	14	TPE	TPE	NNP
cord-017142-vx3rgs4r	57	15	is	be	VBZ
cord-017142-vx3rgs4r	57	16	limited	limit	VBN
cord-017142-vx3rgs4r	57	17	[	[	-LRB-
cord-017142-vx3rgs4r	57	18	21	21	CD
cord-017142-vx3rgs4r	57	19	,	,	,
cord-017142-vx3rgs4r	57	20	29	29	CD
cord-017142-vx3rgs4r	57	21	,	,	,
cord-017142-vx3rgs4r	57	22	63	63	CD
cord-017142-vx3rgs4r	57	23	]	]	-RRB-
cord-017142-vx3rgs4r	57	24	unless	unless	IN
cord-017142-vx3rgs4r	57	25	there	there	EX
cord-017142-vx3rgs4r	57	26	is	be	VBZ
cord-017142-vx3rgs4r	57	27	evidence	evidence	NN
cord-017142-vx3rgs4r	57	28	of	of	IN
cord-017142-vx3rgs4r	57	29	IgM	IgM	NNP
cord-017142-vx3rgs4r	57	30	or	or	CC
cord-017142-vx3rgs4r	57	31	IgA	IgA	NNP
cord-017142-vx3rgs4r	57	32	paraproteinemia	paraproteinemia	NNP
cord-017142-vx3rgs4r	57	33	-	-	HYPH
cord-017142-vx3rgs4r	57	34	associated	associate	VBN
cord-017142-vx3rgs4r	57	35	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	57	36	syndrome	syndrome	NN
cord-017142-vx3rgs4r	57	37	.	.	.
cord-017142-vx3rgs4r	58	1	The	the	DT
cord-017142-vx3rgs4r	58	2	utility	utility	NN
cord-017142-vx3rgs4r	58	3	of	of	IN
cord-017142-vx3rgs4r	58	4	urinary	urinary	JJ
cord-017142-vx3rgs4r	58	5	alkalization	alkalization	NN
cord-017142-vx3rgs4r	58	6	is	be	VBZ
cord-017142-vx3rgs4r	58	7	debated	debate	VBN
cord-017142-vx3rgs4r	58	8	as	as	IN
cord-017142-vx3rgs4r	58	9	this	this	DT
cord-017142-vx3rgs4r	58	10	theoretically	theoretically	RB
cord-017142-vx3rgs4r	58	11	decreases	decrease	VBZ
cord-017142-vx3rgs4r	58	12	tubular	tubular	JJ
cord-017142-vx3rgs4r	58	13	cast	cast	NN
cord-017142-vx3rgs4r	58	14	formation	formation	NN
cord-017142-vx3rgs4r	58	15	and	and	CC
cord-017142-vx3rgs4r	58	16	,	,	,
cord-017142-vx3rgs4r	58	17	however	however	RB
cord-017142-vx3rgs4r	58	18	,	,	,
cord-017142-vx3rgs4r	58	19	can	can	MD
cord-017142-vx3rgs4r	58	20	cause	cause	VB
cord-017142-vx3rgs4r	58	21	risk	risk	NN
cord-017142-vx3rgs4r	58	22	of	of	IN
cord-017142-vx3rgs4r	58	23	renal	renal	JJ
cord-017142-vx3rgs4r	58	24	calcium	calcium	NN
cord-017142-vx3rgs4r	58	25	precipitation	precipitation	NN
cord-017142-vx3rgs4r	58	26	,	,	,
cord-017142-vx3rgs4r	58	27	especially	especially	RB
cord-017142-vx3rgs4r	58	28	if	if	IN
cord-017142-vx3rgs4r	58	29	the	the	DT
cord-017142-vx3rgs4r	58	30	patient	patient	NN
cord-017142-vx3rgs4r	58	31	presents	present	VBZ
cord-017142-vx3rgs4r	58	32	with	with	IN
cord-017142-vx3rgs4r	58	33	concurrent	concurrent	JJ
cord-017142-vx3rgs4r	58	34	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	58	35	.	.	.
cord-017142-vx3rgs4r	59	1	Acute	acute	JJ
cord-017142-vx3rgs4r	59	2	tubular	tubular	JJ
cord-017142-vx3rgs4r	59	3	necrosis	necrosis	NN
cord-017142-vx3rgs4r	59	4	:	:	:
cord-017142-vx3rgs4r	60	1	ATN	ATN	NNP
cord-017142-vx3rgs4r	60	2	is	be	VBZ
cord-017142-vx3rgs4r	60	3	a	a	DT
cord-017142-vx3rgs4r	60	4	consequence	consequence	NN
cord-017142-vx3rgs4r	60	5	of	of	IN
cord-017142-vx3rgs4r	60	6	an	an	DT
cord-017142-vx3rgs4r	60	7	already	already	RB
cord-017142-vx3rgs4r	60	8	compromised	compromise	VBN
cord-017142-vx3rgs4r	60	9	renal	renal	JJ
cord-017142-vx3rgs4r	60	10	function	function	NN
cord-017142-vx3rgs4r	60	11	in	in	IN
cord-017142-vx3rgs4r	60	12	patients	patient	NNS
cord-017142-vx3rgs4r	60	13	with	with	IN
cord-017142-vx3rgs4r	60	14	cast	cast	NN
cord-017142-vx3rgs4r	60	15	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	60	16	.	.	.
cord-017142-vx3rgs4r	61	1	Hypercalcemiarelated	hypercalcemiarelated	JJ
cord-017142-vx3rgs4r	61	2	vasoconstriction	vasoconstriction	NN
cord-017142-vx3rgs4r	61	3	with	with	IN
cord-017142-vx3rgs4r	61	4	subsequent	subsequent	JJ
cord-017142-vx3rgs4r	61	5	reduced	reduce	VBN
cord-017142-vx3rgs4r	61	6	renovascular	renovascular	JJ
cord-017142-vx3rgs4r	61	7	flow	flow	NN
cord-017142-vx3rgs4r	61	8	,	,	,
cord-017142-vx3rgs4r	61	9	dehydration	dehydration	NN
cord-017142-vx3rgs4r	61	10	,	,	,
cord-017142-vx3rgs4r	61	11	and	and	CC
cord-017142-vx3rgs4r	61	12	use	use	NN
cord-017142-vx3rgs4r	61	13	of	of	IN
cord-017142-vx3rgs4r	61	14	loop	loop	NN
cord-017142-vx3rgs4r	61	15	diuretics	diuretic	NNS
cord-017142-vx3rgs4r	61	16	can	can	MD
cord-017142-vx3rgs4r	61	17	speed	speed	VB
cord-017142-vx3rgs4r	61	18	up	up	RP
cord-017142-vx3rgs4r	61	19	cast	cast	NN
cord-017142-vx3rgs4r	61	20	formation	formation	NN
cord-017142-vx3rgs4r	61	21	.	.	.
cord-017142-vx3rgs4r	62	1	There	there	EX
cord-017142-vx3rgs4r	62	2	are	be	VBP
cord-017142-vx3rgs4r	62	3	some	some	DT
cord-017142-vx3rgs4r	62	4	reports	report	NNS
cord-017142-vx3rgs4r	62	5	of	of	IN
cord-017142-vx3rgs4r	62	6	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	62	7	causing	cause	VBG
cord-017142-vx3rgs4r	62	8	direct	direct	JJ
cord-017142-vx3rgs4r	62	9	proximal	proximal	JJ
cord-017142-vx3rgs4r	62	10	tubular	tubular	JJ
cord-017142-vx3rgs4r	62	11	injury	injury	NN
cord-017142-vx3rgs4r	62	12	;	;	:
cord-017142-vx3rgs4r	62	13	however	however	RB
cord-017142-vx3rgs4r	62	14	,	,	,
cord-017142-vx3rgs4r	62	15	the	the	DT
cord-017142-vx3rgs4r	62	16	risk	risk	NN
cord-017142-vx3rgs4r	62	17	appears	appear	VBZ
cord-017142-vx3rgs4r	62	18	to	to	TO
cord-017142-vx3rgs4r	62	19	be	be	VB
cord-017142-vx3rgs4r	62	20	very	very	RB
cord-017142-vx3rgs4r	62	21	small	small	JJ
cord-017142-vx3rgs4r	62	22	[	[	-LRB-
cord-017142-vx3rgs4r	62	23	70	70	CD
cord-017142-vx3rgs4r	62	24	]	]	-RRB-
cord-017142-vx3rgs4r	62	25	.	.	.
cord-017142-vx3rgs4r	63	1	Monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	63	2	deposition	deposition	NN
cord-017142-vx3rgs4r	63	3	disease	disease	NN
cord-017142-vx3rgs4r	63	4	:	:	:
cord-017142-vx3rgs4r	64	1	In	in	IN
cord-017142-vx3rgs4r	64	2	contrast	contrast	NN
cord-017142-vx3rgs4r	64	3	to	to	IN
cord-017142-vx3rgs4r	64	4	myeloma	myeloma	NN
cord-017142-vx3rgs4r	64	5	kidney	kidney	NN
cord-017142-vx3rgs4r	64	6	,	,	,
cord-017142-vx3rgs4r	64	7	MIDD	MIDD	NNP
cord-017142-vx3rgs4r	64	8	(	(	-LRB-
cord-017142-vx3rgs4r	64	9	heavy	heavy	JJ
cord-017142-vx3rgs4r	64	10	chain	chain	NN
cord-017142-vx3rgs4r	64	11	,	,	,
cord-017142-vx3rgs4r	64	12	light	light	JJ
cord-017142-vx3rgs4r	64	13	chain	chain	NN
cord-017142-vx3rgs4r	64	14	,	,	,
cord-017142-vx3rgs4r	64	15	or	or	CC
cord-017142-vx3rgs4r	64	16	heavy	heavy	JJ
cord-017142-vx3rgs4r	64	17	chain	chain	NN
cord-017142-vx3rgs4r	64	18	-	-	HYPH
cord-017142-vx3rgs4r	64	19	light	light	NN
cord-017142-vx3rgs4r	64	20	chain	chain	NN
cord-017142-vx3rgs4r	64	21	)	)	-RRB-
cord-017142-vx3rgs4r	64	22	and	and	CC
cord-017142-vx3rgs4r	64	23	AL	AL	NNP
cord-017142-vx3rgs4r	64	24	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	64	25	result	result	VBP
cord-017142-vx3rgs4r	64	26	from	from	IN
cord-017142-vx3rgs4r	64	27	gradual	gradual	JJ
cord-017142-vx3rgs4r	64	28	non	non	JJ
cord-017142-vx3rgs4r	64	29	-	-	JJ
cord-017142-vx3rgs4r	64	30	fibrillar	fibrillar	JJ
cord-017142-vx3rgs4r	64	31	(	(	-LRB-
cord-017142-vx3rgs4r	64	32	Congo	Congo	NNP
cord-017142-vx3rgs4r	64	33	red	red	JJ
cord-017142-vx3rgs4r	64	34	negative	negative	NN
cord-017142-vx3rgs4r	64	35	)	)	-RRB-
cord-017142-vx3rgs4r	64	36	and	and	CC
cord-017142-vx3rgs4r	64	37	fibrillar	fibrillar	NNP
cord-017142-vx3rgs4r	64	38	(	(	-LRB-
cord-017142-vx3rgs4r	64	39	Congo	Congo	NNP
cord-017142-vx3rgs4r	64	40	red	red	JJ
cord-017142-vx3rgs4r	64	41	positive	positive	JJ
cord-017142-vx3rgs4r	64	42	)	)	-RRB-
cord-017142-vx3rgs4r	64	43	protein	protein	NN
cord-017142-vx3rgs4r	64	44	deposition	deposition	NN
cord-017142-vx3rgs4r	64	45	,	,	,
cord-017142-vx3rgs4r	64	46	respectively	respectively	RB
cord-017142-vx3rgs4r	64	47	,	,	,
cord-017142-vx3rgs4r	64	48	in	in	IN
cord-017142-vx3rgs4r	64	49	the	the	DT
cord-017142-vx3rgs4r	64	50	glomeruli	glomerulus	NNS
cord-017142-vx3rgs4r	64	51	.	.	.
cord-017142-vx3rgs4r	65	1	MIDD	MIDD	NNP
cord-017142-vx3rgs4r	65	2	is	be	VBZ
cord-017142-vx3rgs4r	65	3	most	most	RBS
cord-017142-vx3rgs4r	65	4	commonly	commonly	RB
cord-017142-vx3rgs4r	65	5	kappa	kappa	NN
cord-017142-vx3rgs4r	65	6	subtype	subtype	NN
cord-017142-vx3rgs4r	65	7	,	,	,
cord-017142-vx3rgs4r	65	8	while	while	IN
cord-017142-vx3rgs4r	65	9	AL	AL	NNP
cord-017142-vx3rgs4r	65	10	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	65	11	tends	tend	VBZ
cord-017142-vx3rgs4r	65	12	to	to	TO
cord-017142-vx3rgs4r	65	13	be	be	VB
cord-017142-vx3rgs4r	65	14	lambda	lambda	NN
cord-017142-vx3rgs4r	65	15	;	;	:
cord-017142-vx3rgs4r	65	16	both	both	DT
cord-017142-vx3rgs4r	65	17	tend	tend	VBP
cord-017142-vx3rgs4r	65	18	to	to	TO
cord-017142-vx3rgs4r	65	19	be	be	VB
cord-017142-vx3rgs4r	65	20	associated	associate	VBN
cord-017142-vx3rgs4r	65	21	with	with	IN
cord-017142-vx3rgs4r	65	22	predominant	predominant	JJ
cord-017142-vx3rgs4r	65	23	albuminuria	albuminuria	NNS
cord-017142-vx3rgs4r	65	24	unlike	unlike	IN
cord-017142-vx3rgs4r	65	25	cast	cast	VBN
cord-017142-vx3rgs4r	65	26	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	65	27	.	.	.
cord-017142-vx3rgs4r	66	1	Though	though	IN
cord-017142-vx3rgs4r	66	2	the	the	DT
cord-017142-vx3rgs4r	66	3	most	most	RBS
cord-017142-vx3rgs4r	66	4	characteristic	characteristic	JJ
cord-017142-vx3rgs4r	66	5	presentation	presentation	NN
cord-017142-vx3rgs4r	66	6	is	be	VBZ
cord-017142-vx3rgs4r	66	7	nephrotic	nephrotic	JJ
cord-017142-vx3rgs4r	66	8	syndrome	syndrome	NN
cord-017142-vx3rgs4r	66	9	due	due	IN
cord-017142-vx3rgs4r	66	10	to	to	IN
cord-017142-vx3rgs4r	66	11	glomerular	glomerular	JJ
cord-017142-vx3rgs4r	66	12	involvement	involvement	NN
cord-017142-vx3rgs4r	66	13	,	,	,
cord-017142-vx3rgs4r	66	14	patients	patient	NNS
cord-017142-vx3rgs4r	66	15	with	with	IN
cord-017142-vx3rgs4r	66	16	MIDD	MIDD	NNP
cord-017142-vx3rgs4r	66	17	can	can	MD
cord-017142-vx3rgs4r	66	18	have	have	VB
cord-017142-vx3rgs4r	66	19	rapid	rapid	JJ
cord-017142-vx3rgs4r	66	20	deterioration	deterioration	NN
cord-017142-vx3rgs4r	66	21	of	of	IN
cord-017142-vx3rgs4r	66	22	renal	renal	JJ
cord-017142-vx3rgs4r	66	23	function	function	NN
cord-017142-vx3rgs4r	66	24	which	which	WDT
cord-017142-vx3rgs4r	66	25	could	could	MD
cord-017142-vx3rgs4r	66	26	be	be	VB
cord-017142-vx3rgs4r	66	27	fatal	fatal	JJ
cord-017142-vx3rgs4r	66	28	if	if	IN
cord-017142-vx3rgs4r	66	29	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	66	30	is	be	VBZ
cord-017142-vx3rgs4r	66	31	not	not	RB
cord-017142-vx3rgs4r	66	32	reached	reach	VBN
cord-017142-vx3rgs4r	66	33	in	in	IN
cord-017142-vx3rgs4r	66	34	a	a	DT
cord-017142-vx3rgs4r	66	35	patient	patient	NN
cord-017142-vx3rgs4r	66	36	presenting	present	VBG
cord-017142-vx3rgs4r	66	37	with	with	IN
cord-017142-vx3rgs4r	66	38	new	new	JJ
cord-017142-vx3rgs4r	66	39	-	-	HYPH
cord-017142-vx3rgs4r	66	40	onset	onset	NN
cord-017142-vx3rgs4r	66	41	renal	renal	JJ
cord-017142-vx3rgs4r	66	42	failure	failure	NN
cord-017142-vx3rgs4r	66	43	.	.	.
cord-017142-vx3rgs4r	67	1	Life	life	NN
cord-017142-vx3rgs4r	67	2	-	-	HYPH
cord-017142-vx3rgs4r	67	3	threatening	threaten	VBG
cord-017142-vx3rgs4r	67	4	complications	complication	NNS
cord-017142-vx3rgs4r	67	5	which	which	WDT
cord-017142-vx3rgs4r	67	6	need	need	VBP
cord-017142-vx3rgs4r	67	7	to	to	TO
cord-017142-vx3rgs4r	67	8	be	be	VB
cord-017142-vx3rgs4r	67	9	closely	closely	RB
cord-017142-vx3rgs4r	67	10	monitored	monitor	VBN
cord-017142-vx3rgs4r	67	11	include	include	VBP
cord-017142-vx3rgs4r	67	12	arrhythmias	arrhythmia	NNS
cord-017142-vx3rgs4r	67	13	,	,	,
cord-017142-vx3rgs4r	67	14	congestive	congestive	JJ
cord-017142-vx3rgs4r	67	15	heart	heart	NN
cord-017142-vx3rgs4r	67	16	failure	failure	NN
cord-017142-vx3rgs4r	67	17	,	,	,
cord-017142-vx3rgs4r	67	18	and	and	CC
cord-017142-vx3rgs4r	67	19	bleeding	bleed	VBG
cord-017142-vx3rgs4r	67	20	diathesis	diathesis	NN
cord-017142-vx3rgs4r	67	21	.	.	.
cord-017142-vx3rgs4r	68	1	To	to	TO
cord-017142-vx3rgs4r	68	2	confirm	confirm	VB
cord-017142-vx3rgs4r	68	3	the	the	DT
cord-017142-vx3rgs4r	68	4	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	68	5	,	,	,
cord-017142-vx3rgs4r	68	6	subcutaneous	subcutaneous	JJ
cord-017142-vx3rgs4r	68	7	fat	fat	JJ
cord-017142-vx3rgs4r	68	8	pad	pad	NN
cord-017142-vx3rgs4r	68	9	biopsy	biopsy	NN
cord-017142-vx3rgs4r	68	10	can	can	MD
cord-017142-vx3rgs4r	68	11	be	be	VB
cord-017142-vx3rgs4r	68	12	pursued	pursue	VBN
cord-017142-vx3rgs4r	68	13	initially	initially	RB
cord-017142-vx3rgs4r	68	14	,	,	,
cord-017142-vx3rgs4r	68	15	as	as	IN
cord-017142-vx3rgs4r	68	16	it	-PRON-	PRP
cord-017142-vx3rgs4r	68	17	is	be	VBZ
cord-017142-vx3rgs4r	68	18	less	less	RBR
cord-017142-vx3rgs4r	68	19	invasive	invasive	JJ
cord-017142-vx3rgs4r	68	20	and	and	CC
cord-017142-vx3rgs4r	68	21	can	can	MD
cord-017142-vx3rgs4r	68	22	potentially	potentially	RB
cord-017142-vx3rgs4r	68	23	diagnose	diagnose	VB
cord-017142-vx3rgs4r	68	24	an	an	DT
cord-017142-vx3rgs4r	68	25	AL	AL	NNP
cord-017142-vx3rgs4r	68	26	amyloid	amyloid	NN
cord-017142-vx3rgs4r	68	27	deposition	deposition	NN
cord-017142-vx3rgs4r	68	28	disease	disease	NN
cord-017142-vx3rgs4r	68	29	.	.	.
cord-017142-vx3rgs4r	69	1	If	if	IN
cord-017142-vx3rgs4r	69	2	negative	negative	JJ
cord-017142-vx3rgs4r	69	3	,	,	,
cord-017142-vx3rgs4r	69	4	proceed	proceed	VBP
cord-017142-vx3rgs4r	69	5	with	with	IN
cord-017142-vx3rgs4r	69	6	kidney	kidney	NN
cord-017142-vx3rgs4r	69	7	biopsy	biopsy	NN
cord-017142-vx3rgs4r	69	8	to	to	TO
cord-017142-vx3rgs4r	69	9	look	look	VB
cord-017142-vx3rgs4r	69	10	for	for	IN
cord-017142-vx3rgs4r	69	11	AL	AL	NNP
cord-017142-vx3rgs4r	69	12	amyloid	amyloid	NN
cord-017142-vx3rgs4r	69	13	,	,	,
cord-017142-vx3rgs4r	69	14	MIDD	MIDD	NNP
cord-017142-vx3rgs4r	69	15	,	,	,
cord-017142-vx3rgs4r	69	16	or	or	CC
cord-017142-vx3rgs4r	69	17	other	other	JJ
cord-017142-vx3rgs4r	69	18	potential	potential	JJ
cord-017142-vx3rgs4r	69	19	renal	renal	JJ
cord-017142-vx3rgs4r	69	20	glomerulopathy	glomerulopathy	NNP
cord-017142-vx3rgs4r	69	21	.	.	.
cord-017142-vx3rgs4r	70	1	Fanconi	Fanconi	NNP
cord-017142-vx3rgs4r	70	2	syndrome	syndrome	NN
cord-017142-vx3rgs4r	70	3	:	:	:
cord-017142-vx3rgs4r	71	1	The	the	DT
cord-017142-vx3rgs4r	71	2	presence	presence	NN
cord-017142-vx3rgs4r	71	3	of	of	IN
cord-017142-vx3rgs4r	71	4	hypophosphatemia	hypophosphatemia	NN
cord-017142-vx3rgs4r	71	5	,	,	,
cord-017142-vx3rgs4r	71	6	hypokalemia	hypokalemia	NN
cord-017142-vx3rgs4r	71	7	,	,	,
cord-017142-vx3rgs4r	71	8	hypouricemia	hypouricemia	NN
cord-017142-vx3rgs4r	71	9	,	,	,
cord-017142-vx3rgs4r	71	10	renal	renal	JJ
cord-017142-vx3rgs4r	71	11	tubular	tubular	JJ
cord-017142-vx3rgs4r	71	12	acidosis	acidosis	NN
cord-017142-vx3rgs4r	71	13	,	,	,
cord-017142-vx3rgs4r	71	14	and	and	CC
cord-017142-vx3rgs4r	71	15	glycosuria	glycosuria	NNP
cord-017142-vx3rgs4r	71	16	should	should	MD
cord-017142-vx3rgs4r	71	17	raise	raise	VB
cord-017142-vx3rgs4r	71	18	the	the	DT
cord-017142-vx3rgs4r	71	19	suspicion	suspicion	NN
cord-017142-vx3rgs4r	71	20	of	of	IN
cord-017142-vx3rgs4r	71	21	Fanconi	Fanconi	NNP
cord-017142-vx3rgs4r	71	22	syndrome	syndrome	NN
cord-017142-vx3rgs4r	71	23	in	in	IN
cord-017142-vx3rgs4r	71	24	MM	MM	NNP
cord-017142-vx3rgs4r	71	25	.	.	.
cord-017142-vx3rgs4r	72	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	72	2	is	be	VBZ
cord-017142-vx3rgs4r	72	3	a	a	DT
cord-017142-vx3rgs4r	72	4	rare	rare	JJ
cord-017142-vx3rgs4r	72	5	wasting	wasting	NN
cord-017142-vx3rgs4r	72	6	syndrome	syndrome	NN
cord-017142-vx3rgs4r	72	7	due	due	IN
cord-017142-vx3rgs4r	72	8	to	to	IN
cord-017142-vx3rgs4r	72	9	proximal	proximal	JJ
cord-017142-vx3rgs4r	72	10	renal	renal	JJ
cord-017142-vx3rgs4r	72	11	tubule	tubule	NN
cord-017142-vx3rgs4r	72	12	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	72	13	more	more	RBR
cord-017142-vx3rgs4r	72	14	commonly	commonly	RB
cord-017142-vx3rgs4r	72	15	seen	see	VBN
cord-017142-vx3rgs4r	72	16	in	in	IN
cord-017142-vx3rgs4r	72	17	patients	patient	NNS
cord-017142-vx3rgs4r	72	18	with	with	IN
cord-017142-vx3rgs4r	72	19	MGUS	MGUS	NNP
cord-017142-vx3rgs4r	72	20	leading	lead	VBG
cord-017142-vx3rgs4r	72	21	to	to	IN
cord-017142-vx3rgs4r	72	22	loss	loss	NN
cord-017142-vx3rgs4r	72	23	of	of	IN
cord-017142-vx3rgs4r	72	24	glucose	glucose	NN
cord-017142-vx3rgs4r	72	25	,	,	,
cord-017142-vx3rgs4r	72	26	phosphate	phosphate	NN
cord-017142-vx3rgs4r	72	27	,	,	,
cord-017142-vx3rgs4r	72	28	amino	amino	JJ
cord-017142-vx3rgs4r	72	29	acids	acid	NNS
cord-017142-vx3rgs4r	72	30	,	,	,
cord-017142-vx3rgs4r	72	31	and	and	CC
cord-017142-vx3rgs4r	72	32	uric	uric	NN
cord-017142-vx3rgs4r	72	33	acid	acid	NN
cord-017142-vx3rgs4r	72	34	.	.	.
cord-017142-vx3rgs4r	73	1	Though	though	IN
cord-017142-vx3rgs4r	73	2	it	-PRON-	PRP
cord-017142-vx3rgs4r	73	3	runs	run	VBZ
cord-017142-vx3rgs4r	73	4	a	a	DT
cord-017142-vx3rgs4r	73	5	benign	benign	JJ
cord-017142-vx3rgs4r	73	6	course	course	NN
cord-017142-vx3rgs4r	73	7	,	,	,
cord-017142-vx3rgs4r	73	8	it	-PRON-	PRP
cord-017142-vx3rgs4r	73	9	can	can	MD
cord-017142-vx3rgs4r	73	10	complicate	complicate	VB
cord-017142-vx3rgs4r	73	11	the	the	DT
cord-017142-vx3rgs4r	73	12	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	73	13	electrolyte	electrolyte	JJ
cord-017142-vx3rgs4r	73	14	imbalance	imbalance	NN
cord-017142-vx3rgs4r	73	15	and	and	CC
cord-017142-vx3rgs4r	73	16	renal	renal	JJ
cord-017142-vx3rgs4r	73	17	failure	failure	NN
cord-017142-vx3rgs4r	73	18	.	.	.
cord-017142-vx3rgs4r	74	1	Ironically	ironically	RB
cord-017142-vx3rgs4r	74	2	,	,	,
cord-017142-vx3rgs4r	74	3	despite	despite	IN
cord-017142-vx3rgs4r	74	4	the	the	DT
cord-017142-vx3rgs4r	74	5	glycosuria	glycosuria	NNP
cord-017142-vx3rgs4r	74	6	,	,	,
cord-017142-vx3rgs4r	74	7	the	the	DT
cord-017142-vx3rgs4r	74	8	serum	serum	NN
cord-017142-vx3rgs4r	74	9	glucose	glucose	NN
cord-017142-vx3rgs4r	74	10	is	be	VBZ
cord-017142-vx3rgs4r	74	11	usually	usually	RB
cord-017142-vx3rgs4r	74	12	normal	normal	JJ
cord-017142-vx3rgs4r	74	13	,	,	,
cord-017142-vx3rgs4r	74	14	which	which	WDT
cord-017142-vx3rgs4r	74	15	goes	go	VBZ
cord-017142-vx3rgs4r	74	16	along	along	IN
cord-017142-vx3rgs4r	74	17	with	with	IN
cord-017142-vx3rgs4r	74	18	the	the	DT
cord-017142-vx3rgs4r	74	19	defect	defect	NN
cord-017142-vx3rgs4r	74	20	in	in	IN
cord-017142-vx3rgs4r	74	21	the	the	DT
cord-017142-vx3rgs4r	74	22	proximal	proximal	JJ
cord-017142-vx3rgs4r	74	23	tubular	tubular	JJ
cord-017142-vx3rgs4r	74	24	transport	transport	NN
cord-017142-vx3rgs4r	74	25	defect	defect	NN
cord-017142-vx3rgs4r	74	26	[	[	-LRB-
cord-017142-vx3rgs4r	74	27	15	15	CD
cord-017142-vx3rgs4r	74	28	]	]	-RRB-
cord-017142-vx3rgs4r	74	29	.	.	.
cord-017142-vx3rgs4r	75	1	MM	MM	NNP
cord-017142-vx3rgs4r	75	2	patients	patient	NNS
cord-017142-vx3rgs4r	75	3	are	be	VBP
cord-017142-vx3rgs4r	75	4	at	at	IN
cord-017142-vx3rgs4r	75	5	high	high	JJ
cord-017142-vx3rgs4r	75	6	risk	risk	NN
cord-017142-vx3rgs4r	75	7	for	for	IN
cord-017142-vx3rgs4r	75	8	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	75	9	complications	complication	NNS
cord-017142-vx3rgs4r	75	10	secondary	secondary	JJ
cord-017142-vx3rgs4r	75	11	multiple	multiple	JJ
cord-017142-vx3rgs4r	75	12	factors	factor	NNS
cord-017142-vx3rgs4r	75	13	including	include	VBG
cord-017142-vx3rgs4r	75	14	an	an	DT
cord-017142-vx3rgs4r	75	15	older	old	JJR
cord-017142-vx3rgs4r	75	16	age	age	NN
cord-017142-vx3rgs4r	75	17	group	group	NN
cord-017142-vx3rgs4r	75	18	of	of	IN
cord-017142-vx3rgs4r	75	19	patients	patient	NNS
cord-017142-vx3rgs4r	75	20	with	with	IN
cord-017142-vx3rgs4r	75	21	underlying	underlying	JJ
cord-017142-vx3rgs4r	75	22	comorbidities	comorbiditie	NNS
cord-017142-vx3rgs4r	75	23	,	,	,
cord-017142-vx3rgs4r	75	24	concurrent	concurrent	JJ
cord-017142-vx3rgs4r	75	25	kidney	kidney	NN
cord-017142-vx3rgs4r	75	26	involvement	involvement	NN
cord-017142-vx3rgs4r	75	27	,	,	,
cord-017142-vx3rgs4r	75	28	MM	MM	NNP
cord-017142-vx3rgs4r	75	29	-	-	HYPH
cord-017142-vx3rgs4r	75	30	associated	associate	VBN
cord-017142-vx3rgs4r	75	31	deposition	deposition	NN
cord-017142-vx3rgs4r	75	32	disease	disease	NN
cord-017142-vx3rgs4r	75	33	,	,	,
cord-017142-vx3rgs4r	75	34	and/or	and/or	CC
cord-017142-vx3rgs4r	75	35	anti	anti	JJ
cord-017142-vx3rgs4r	75	36	-	-	JJ
cord-017142-vx3rgs4r	75	37	MM	mm	JJ
cord-017142-vx3rgs4r	75	38	drug	drug	NN
cord-017142-vx3rgs4r	75	39	-	-	HYPH
cord-017142-vx3rgs4r	75	40	related	relate	VBN
cord-017142-vx3rgs4r	75	41	side	side	NN
cord-017142-vx3rgs4r	75	42	effects	effect	NNS
cord-017142-vx3rgs4r	75	43	.	.	.
cord-017142-vx3rgs4r	76	1	Cardiac	cardiac	JJ
cord-017142-vx3rgs4r	76	2	amyloid	amyloid	NN
cord-017142-vx3rgs4r	76	3	:	:	:
cord-017142-vx3rgs4r	77	1	Approximately	approximately	RB
cord-017142-vx3rgs4r	77	2	10	10	CD
cord-017142-vx3rgs4r	77	3	%	%	NN
cord-017142-vx3rgs4r	77	4	of	of	IN
cord-017142-vx3rgs4r	77	5	patients	patient	NNS
cord-017142-vx3rgs4r	77	6	with	with	IN
cord-017142-vx3rgs4r	77	7	MM	MM	NNP
cord-017142-vx3rgs4r	77	8	can	can	MD
cord-017142-vx3rgs4r	77	9	have	have	VB
cord-017142-vx3rgs4r	77	10	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	77	11	light	light	JJ
cord-017142-vx3rgs4r	77	12	chain	chain	NN
cord-017142-vx3rgs4r	78	1	(	(	-LRB-
cord-017142-vx3rgs4r	78	2	AL	AL	NNP
cord-017142-vx3rgs4r	78	3	)	)	-RRB-
cord-017142-vx3rgs4r	78	4	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	78	5	,	,	,
cord-017142-vx3rgs4r	78	6	the	the	DT
cord-017142-vx3rgs4r	78	7	most	most	RBS
cord-017142-vx3rgs4r	78	8	common	common	JJ
cord-017142-vx3rgs4r	78	9	type	type	NN
cord-017142-vx3rgs4r	78	10	of	of	IN
cord-017142-vx3rgs4r	78	11	systemic	systemic	JJ
cord-017142-vx3rgs4r	78	12	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	78	13	associated	associate	VBN
cord-017142-vx3rgs4r	78	14	with	with	IN
cord-017142-vx3rgs4r	78	15	plasma	plasma	NN
cord-017142-vx3rgs4r	78	16	cell	cell	NN
cord-017142-vx3rgs4r	78	17	dyscrasias	dyscrasia	NNS
cord-017142-vx3rgs4r	78	18	;	;	:
cord-017142-vx3rgs4r	78	19	often	often	RB
cord-017142-vx3rgs4r	78	20	this	this	DT
cord-017142-vx3rgs4r	78	21	association	association	NN
cord-017142-vx3rgs4r	78	22	is	be	VBZ
cord-017142-vx3rgs4r	78	23	missed	miss	VBN
cord-017142-vx3rgs4r	78	24	at	at	IN
cord-017142-vx3rgs4r	78	25	the	the	DT
cord-017142-vx3rgs4r	78	26	time	time	NN
cord-017142-vx3rgs4r	78	27	of	of	IN
cord-017142-vx3rgs4r	78	28	MM	MM	NNP
cord-017142-vx3rgs4r	78	29	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	78	30	.	.	.
cord-017142-vx3rgs4r	79	1	In	in	IN
cord-017142-vx3rgs4r	79	2	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	79	3	,	,	,
cord-017142-vx3rgs4r	79	4	heart	heart	NN
cord-017142-vx3rgs4r	79	5	involvement	involvement	NN
cord-017142-vx3rgs4r	79	6	is	be	VBZ
cord-017142-vx3rgs4r	79	7	seen	see	VBN
cord-017142-vx3rgs4r	79	8	in	in	IN
cord-017142-vx3rgs4r	79	9	approximately	approximately	RB
cord-017142-vx3rgs4r	79	10	half	half	NN
cord-017142-vx3rgs4r	79	11	of	of	IN
cord-017142-vx3rgs4r	79	12	the	the	DT
cord-017142-vx3rgs4r	79	13	cases	case	NNS
cord-017142-vx3rgs4r	79	14	[	[	-LRB-
cord-017142-vx3rgs4r	79	15	32	32	CD
cord-017142-vx3rgs4r	79	16	]	]	-RRB-
cord-017142-vx3rgs4r	79	17	.	.	.
cord-017142-vx3rgs4r	80	1	Cardiac	cardiac	JJ
cord-017142-vx3rgs4r	80	2	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	80	3	can	can	MD
cord-017142-vx3rgs4r	80	4	be	be	VB
cord-017142-vx3rgs4r	80	5	clinically	clinically	RB
cord-017142-vx3rgs4r	80	6	silent	silent	JJ
cord-017142-vx3rgs4r	80	7	initially	initially	RB
cord-017142-vx3rgs4r	80	8	,	,	,
cord-017142-vx3rgs4r	80	9	and	and	CC
cord-017142-vx3rgs4r	80	10	a	a	DT
cord-017142-vx3rgs4r	80	11	MM	MM	NNP
cord-017142-vx3rgs4r	80	12	patient	patient	NN
cord-017142-vx3rgs4r	80	13	presenting	present	VBG
cord-017142-vx3rgs4r	80	14	with	with	IN
cord-017142-vx3rgs4r	80	15	progressive	progressive	JJ
cord-017142-vx3rgs4r	80	16	dyspnea	dyspnea	NN
cord-017142-vx3rgs4r	81	1	,	,	,
cord-017142-vx3rgs4r	81	2	worsening	worsen	VBG
cord-017142-vx3rgs4r	81	3	edema	edema	NN
cord-017142-vx3rgs4r	81	4	with	with	IN
cord-017142-vx3rgs4r	81	5	evidence	evidence	NN
cord-017142-vx3rgs4r	81	6	of	of	IN
cord-017142-vx3rgs4r	81	7	heart	heart	NN
cord-017142-vx3rgs4r	81	8	failure	failure	NN
cord-017142-vx3rgs4r	81	9	,	,	,
cord-017142-vx3rgs4r	81	10	or	or	CC
cord-017142-vx3rgs4r	81	11	dysrhythmia	dysrhythmia	NN
cord-017142-vx3rgs4r	81	12	presenting	present	VBG
cord-017142-vx3rgs4r	81	13	as	as	IN
cord-017142-vx3rgs4r	81	14	syncope	syncope	NN
cord-017142-vx3rgs4r	81	15	or	or	CC
cord-017142-vx3rgs4r	81	16	hypotensive	hypotensive	JJ
cord-017142-vx3rgs4r	81	17	event	event	NN
cord-017142-vx3rgs4r	81	18	requires	require	VBZ
cord-017142-vx3rgs4r	81	19	a	a	DT
cord-017142-vx3rgs4r	81	20	thorough	thorough	JJ
cord-017142-vx3rgs4r	81	21	work	work	NN
cord-017142-vx3rgs4r	81	22	-	-	HYPH
cord-017142-vx3rgs4r	81	23	up	up	NN
cord-017142-vx3rgs4r	81	24	to	to	TO
cord-017142-vx3rgs4r	81	25	rule	rule	VB
cord-017142-vx3rgs4r	81	26	out	out	RP
cord-017142-vx3rgs4r	81	27	coexisting	coexist	VBG
cord-017142-vx3rgs4r	81	28	amyloid	amyloid	NN
cord-017142-vx3rgs4r	81	29	disease	disease	NN
cord-017142-vx3rgs4r	81	30	.	.	.
cord-017142-vx3rgs4r	82	1	Detection	detection	NN
cord-017142-vx3rgs4r	82	2	of	of	IN
cord-017142-vx3rgs4r	82	3	amyloid	amyloid	NN
cord-017142-vx3rgs4r	82	4	in	in	IN
cord-017142-vx3rgs4r	82	5	any	any	DT
cord-017142-vx3rgs4r	82	6	organ	organ	NN
cord-017142-vx3rgs4r	82	7	requires	require	VBZ
cord-017142-vx3rgs4r	82	8	ruling	rule	VBG
cord-017142-vx3rgs4r	82	9	out	out	RP
cord-017142-vx3rgs4r	82	10	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	82	11	involvement	involvement	NN
cord-017142-vx3rgs4r	82	12	.	.	.
cord-017142-vx3rgs4r	83	1	Other	other	JJ
cord-017142-vx3rgs4r	83	2	symptoms	symptom	NNS
cord-017142-vx3rgs4r	83	3	which	which	WDT
cord-017142-vx3rgs4r	83	4	warrant	warrant	VBP
cord-017142-vx3rgs4r	83	5	amyloid	amyloid	NN
cord-017142-vx3rgs4r	83	6	work	work	NN
cord-017142-vx3rgs4r	83	7	-	-	HYPH
cord-017142-vx3rgs4r	83	8	up	up	NN
cord-017142-vx3rgs4r	83	9	include	include	VBP
cord-017142-vx3rgs4r	83	10	easy	easy	JJ
cord-017142-vx3rgs4r	83	11	bruising	bruising	NN
cord-017142-vx3rgs4r	83	12	,	,	,
cord-017142-vx3rgs4r	83	13	periorbital	periorbital	NNP
cord-017142-vx3rgs4r	83	14	purpura	purpura	NN
cord-017142-vx3rgs4r	83	15	,	,	,
cord-017142-vx3rgs4r	83	16	macroglossia	macroglossia	NNP
cord-017142-vx3rgs4r	83	17	(	(	-LRB-
cord-017142-vx3rgs4r	83	18	which	which	WDT
cord-017142-vx3rgs4r	83	19	is	be	VBZ
cord-017142-vx3rgs4r	83	20	better	well	RBR
cord-017142-vx3rgs4r	83	21	appreciated	appreciate	VBN
cord-017142-vx3rgs4r	83	22	when	when	WRB
cord-017142-vx3rgs4r	83	23	associated	associate	VBN
cord-017142-vx3rgs4r	83	24	with	with	IN
cord-017142-vx3rgs4r	83	25	tooth	tooth	NN
cord-017142-vx3rgs4r	83	26	indentation	indentation	NN
cord-017142-vx3rgs4r	83	27	)	)	-RRB-
cord-017142-vx3rgs4r	83	28	,	,	,
cord-017142-vx3rgs4r	83	29	and	and	CC
cord-017142-vx3rgs4r	83	30	carpal	carpal	NN
cord-017142-vx3rgs4r	83	31	tunnel	tunnel	NN
cord-017142-vx3rgs4r	83	32	syndrome	syndrome	NN
cord-017142-vx3rgs4r	83	33	.	.	.
cord-017142-vx3rgs4r	84	1	Once	once	IN
cord-017142-vx3rgs4r	84	2	significant	significant	JJ
cord-017142-vx3rgs4r	84	3	symptoms	symptom	NNS
cord-017142-vx3rgs4r	84	4	of	of	IN
cord-017142-vx3rgs4r	84	5	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	84	6	amyloid	amyloid	NN
cord-017142-vx3rgs4r	84	7	appear	appear	VBP
cord-017142-vx3rgs4r	84	8	,	,	,
cord-017142-vx3rgs4r	84	9	most	most	RBS
cord-017142-vx3rgs4r	84	10	commonly	commonly	RB
cord-017142-vx3rgs4r	84	11	related	relate	VBN
cord-017142-vx3rgs4r	84	12	to	to	IN
cord-017142-vx3rgs4r	84	13	heart	heart	NN
cord-017142-vx3rgs4r	84	14	failure	failure	NN
cord-017142-vx3rgs4r	84	15	,	,	,
cord-017142-vx3rgs4r	84	16	median	median	JJ
cord-017142-vx3rgs4r	84	17	survival	survival	NN
cord-017142-vx3rgs4r	84	18	shortens	shorten	VBZ
cord-017142-vx3rgs4r	84	19	,	,	,
cord-017142-vx3rgs4r	84	20	especially	especially	RB
cord-017142-vx3rgs4r	84	21	in	in	IN
cord-017142-vx3rgs4r	84	22	the	the	DT
cord-017142-vx3rgs4r	84	23	event	event	NN
cord-017142-vx3rgs4r	84	24	of	of	IN
cord-017142-vx3rgs4r	84	25	a	a	DT
cord-017142-vx3rgs4r	84	26	late	late	JJ
cord-017142-vx3rgs4r	84	27	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	84	28	.	.	.
cord-017142-vx3rgs4r	85	1	Amyloid	amyloid	JJ
cord-017142-vx3rgs4r	85	2	deposition	deposition	NN
cord-017142-vx3rgs4r	85	3	takes	take	VBZ
cord-017142-vx3rgs4r	85	4	place	place	NN
cord-017142-vx3rgs4r	85	5	extracellularly	extracellularly	RB
cord-017142-vx3rgs4r	85	6	throughout	throughout	IN
cord-017142-vx3rgs4r	85	7	the	the	DT
cord-017142-vx3rgs4r	85	8	ventricles	ventricle	NNS
cord-017142-vx3rgs4r	85	9	,	,	,
cord-017142-vx3rgs4r	85	10	atria	atria	NN
cord-017142-vx3rgs4r	85	11	,	,	,
cord-017142-vx3rgs4r	85	12	valves	valve	NNS
cord-017142-vx3rgs4r	85	13	,	,	,
cord-017142-vx3rgs4r	85	14	conduction	conduction	NN
cord-017142-vx3rgs4r	85	15	system	system	NN
cord-017142-vx3rgs4r	85	16	,	,	,
cord-017142-vx3rgs4r	85	17	and	and	CC
cord-017142-vx3rgs4r	85	18	in	in	IN
cord-017142-vx3rgs4r	85	19	the	the	DT
cord-017142-vx3rgs4r	85	20	perivascular	perivascular	JJ
cord-017142-vx3rgs4r	85	21	regions	region	NNS
cord-017142-vx3rgs4r	85	22	of	of	IN
cord-017142-vx3rgs4r	85	23	small	small	JJ
cord-017142-vx3rgs4r	85	24	vessels	vessel	NNS
cord-017142-vx3rgs4r	85	25	.	.	.
cord-017142-vx3rgs4r	86	1	This	this	DT
cord-017142-vx3rgs4r	86	2	eventually	eventually	RB
cord-017142-vx3rgs4r	86	3	leads	lead	VBZ
cord-017142-vx3rgs4r	86	4	to	to	IN
cord-017142-vx3rgs4r	86	5	thickened	thickened	JJ
cord-017142-vx3rgs4r	86	6	,	,	,
cord-017142-vx3rgs4r	86	7	non	non	JJ
cord-017142-vx3rgs4r	86	8	-	-	JJ
cord-017142-vx3rgs4r	86	9	dilated	dilated	JJ
cord-017142-vx3rgs4r	86	10	ventricles	ventricle	NNS
cord-017142-vx3rgs4r	86	11	as	as	RB
cord-017142-vx3rgs4r	86	12	well	well	RB
cord-017142-vx3rgs4r	86	13	as	as	IN
cord-017142-vx3rgs4r	86	14	atrial	atrial	JJ
cord-017142-vx3rgs4r	86	15	thickening	thickening	NN
cord-017142-vx3rgs4r	86	16	that	that	WDT
cord-017142-vx3rgs4r	86	17	eventually	eventually	RB
cord-017142-vx3rgs4r	86	18	progresses	progress	VBZ
cord-017142-vx3rgs4r	86	19	to	to	TO
cord-017142-vx3rgs4r	86	20	thinned	thin	VBN
cord-017142-vx3rgs4r	86	21	dilated	dilated	JJ
cord-017142-vx3rgs4r	86	22	atria	atria	NN
cord-017142-vx3rgs4r	86	23	.	.	.
cord-017142-vx3rgs4r	87	1	The	the	DT
cord-017142-vx3rgs4r	87	2	serum	serum	NN
cord-017142-vx3rgs4r	87	3	concentration	concentration	NN
cord-017142-vx3rgs4r	87	4	of	of	IN
cord-017142-vx3rgs4r	87	5	free	free	JJ
cord-017142-vx3rgs4r	87	6	light	light	JJ
cord-017142-vx3rgs4r	87	7	chains	chain	NNS
cord-017142-vx3rgs4r	87	8	and	and	CC
cord-017142-vx3rgs4r	87	9	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	87	10	enzymes	enzyme	NNS
cord-017142-vx3rgs4r	87	11	(	(	-LRB-
cord-017142-vx3rgs4r	87	12	N	n	CD
cord-017142-vx3rgs4r	87	13	-	-	HYPH
cord-017142-vx3rgs4r	87	14	terminal	terminal	NN
cord-017142-vx3rgs4r	87	15	pro	pro	JJ
cord-017142-vx3rgs4r	87	16	-	-	JJ
cord-017142-vx3rgs4r	87	17	brain	brain	JJ
cord-017142-vx3rgs4r	87	18	natriuretic	natriuretic	JJ
cord-017142-vx3rgs4r	87	19	peptide	peptide	NN
cord-017142-vx3rgs4r	87	20	and	and	CC
cord-017142-vx3rgs4r	87	21	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	87	22	troponins	troponin	NNS
cord-017142-vx3rgs4r	87	23	)	)	-RRB-
cord-017142-vx3rgs4r	87	24	are	be	VBP
cord-017142-vx3rgs4r	87	25	sensitive	sensitive	JJ
cord-017142-vx3rgs4r	87	26	markers	marker	NNS
cord-017142-vx3rgs4r	87	27	for	for	IN
cord-017142-vx3rgs4r	87	28	systemic	systemic	JJ
cord-017142-vx3rgs4r	87	29	and	and	CC
cord-017142-vx3rgs4r	87	30	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	87	31	involvement	involvement	NN
cord-017142-vx3rgs4r	87	32	,	,	,
cord-017142-vx3rgs4r	87	33	respectively	respectively	RB
cord-017142-vx3rgs4r	87	34	,	,	,
cord-017142-vx3rgs4r	87	35	in	in	IN
cord-017142-vx3rgs4r	87	36	AL	AL	NNP
cord-017142-vx3rgs4r	87	37	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	87	38	[	[	-LRB-
cord-017142-vx3rgs4r	87	39	116	116	CD
cord-017142-vx3rgs4r	87	40	]	]	-RRB-
cord-017142-vx3rgs4r	87	41	.	.	.
cord-017142-vx3rgs4r	88	1	N	n	CD
cord-017142-vx3rgs4r	88	2	-	-	HYPH
cord-017142-vx3rgs4r	88	3	terminal	terminal	NN
cord-017142-vx3rgs4r	88	4	pro	pro	JJ
cord-017142-vx3rgs4r	88	5	-	-	JJ
cord-017142-vx3rgs4r	88	6	B	b	NN
cord-017142-vx3rgs4r	88	7	-	-	HYPH
cord-017142-vx3rgs4r	88	8	type	type	NN
cord-017142-vx3rgs4r	88	9	natriuretic	natriuretic	JJ
cord-017142-vx3rgs4r	88	10	peptide	peptide	NN
cord-017142-vx3rgs4r	88	11	levels	level	NNS
cord-017142-vx3rgs4r	88	12	are	be	VBP
cord-017142-vx3rgs4r	88	13	elevated	elevate	VBN
cord-017142-vx3rgs4r	88	14	in	in	IN
cord-017142-vx3rgs4r	88	15	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	88	16	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	88	17	,	,	,
cord-017142-vx3rgs4r	88	18	even	even	RB
cord-017142-vx3rgs4r	88	19	in	in	IN
cord-017142-vx3rgs4r	88	20	the	the	DT
cord-017142-vx3rgs4r	88	21	absence	absence	NN
cord-017142-vx3rgs4r	88	22	of	of	IN
cord-017142-vx3rgs4r	88	23	heart	heart	NN
cord-017142-vx3rgs4r	88	24	failure	failure	NN
cord-017142-vx3rgs4r	88	25	,	,	,
cord-017142-vx3rgs4r	88	26	due	due	IN
cord-017142-vx3rgs4r	88	27	to	to	IN
cord-017142-vx3rgs4r	88	28	regional	regional	JJ
cord-017142-vx3rgs4r	88	29	myocardial	myocardial	JJ
cord-017142-vx3rgs4r	88	30	stress	stress	NN
cord-017142-vx3rgs4r	88	31	due	due	IN
cord-017142-vx3rgs4r	88	32	to	to	IN
cord-017142-vx3rgs4r	88	33	fibrillar	fibrillar	NNP
cord-017142-vx3rgs4r	88	34	extracellular	extracellular	JJ
cord-017142-vx3rgs4r	88	35	deposition	deposition	NN
cord-017142-vx3rgs4r	88	36	[	[	-LRB-
cord-017142-vx3rgs4r	88	37	90	90	CD
cord-017142-vx3rgs4r	88	38	]	]	-RRB-
cord-017142-vx3rgs4r	88	39	.	.	.
cord-017142-vx3rgs4r	89	1	Cardiac	cardiac	JJ
cord-017142-vx3rgs4r	89	2	troponins	troponin	NNS
cord-017142-vx3rgs4r	89	3	can	can	MD
cord-017142-vx3rgs4r	89	4	be	be	VB
cord-017142-vx3rgs4r	89	5	elevated	elevate	VBN
cord-017142-vx3rgs4r	89	6	,	,	,
cord-017142-vx3rgs4r	89	7	even	even	RB
cord-017142-vx3rgs4r	89	8	with	with	IN
cord-017142-vx3rgs4r	89	9	an	an	DT
cord-017142-vx3rgs4r	89	10	unremarkable	unremarkable	JJ
cord-017142-vx3rgs4r	89	11	coronary	coronary	JJ
cord-017142-vx3rgs4r	89	12	angiography	angiography	NN
cord-017142-vx3rgs4r	89	13	,	,	,
cord-017142-vx3rgs4r	89	14	due	due	IN
cord-017142-vx3rgs4r	89	15	to	to	IN
cord-017142-vx3rgs4r	89	16	predominant	predominant	JJ
cord-017142-vx3rgs4r	89	17	deposition	deposition	NN
cord-017142-vx3rgs4r	89	18	in	in	IN
cord-017142-vx3rgs4r	89	19	the	the	DT
cord-017142-vx3rgs4r	89	20	small	small	JJ
cord-017142-vx3rgs4r	89	21	intramural	intramural	JJ
cord-017142-vx3rgs4r	89	22	vessels	vessel	NNS
cord-017142-vx3rgs4r	89	23	sparing	spare	VBG
cord-017142-vx3rgs4r	89	24	the	the	DT
cord-017142-vx3rgs4r	89	25	epicardial	epicardial	JJ
cord-017142-vx3rgs4r	89	26	arteries	artery	NNS
cord-017142-vx3rgs4r	89	27	,	,	,
cord-017142-vx3rgs4r	89	28	but	but	CC
cord-017142-vx3rgs4r	89	29	associated	associate	VBN
cord-017142-vx3rgs4r	89	30	with	with	IN
cord-017142-vx3rgs4r	89	31	nonischemic	nonischemic	JJ
cord-017142-vx3rgs4r	89	32	destruction	destruction	NN
cord-017142-vx3rgs4r	89	33	of	of	IN
cord-017142-vx3rgs4r	89	34	cardiomyocytes	cardiomyocyte	NNS
cord-017142-vx3rgs4r	89	35	.	.	.
cord-017142-vx3rgs4r	90	1	ECG	ECG	NNP
cord-017142-vx3rgs4r	90	2	findings	finding	NNS
cord-017142-vx3rgs4r	90	3	suggestive	suggestive	JJ
cord-017142-vx3rgs4r	90	4	of	of	IN
cord-017142-vx3rgs4r	90	5	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	90	6	involvement	involvement	NN
cord-017142-vx3rgs4r	90	7	include	include	VBP
cord-017142-vx3rgs4r	90	8	a	a	DT
cord-017142-vx3rgs4r	90	9	pattern	pattern	NN
cord-017142-vx3rgs4r	90	10	of	of	IN
cord-017142-vx3rgs4r	90	11	low	low	JJ
cord-017142-vx3rgs4r	90	12	voltage	voltage	NN
cord-017142-vx3rgs4r	90	13	(	(	-LRB-
cord-017142-vx3rgs4r	90	14	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	90	15	changes	change	NNS
cord-017142-vx3rgs4r	90	16	from	from	IN
cord-017142-vx3rgs4r	90	17	amyloid	amyloid	JJ
cord-017142-vx3rgs4r	90	18	infiltration	infiltration	NN
cord-017142-vx3rgs4r	90	19	rather	rather	RB
cord-017142-vx3rgs4r	90	20	than	than	IN
cord-017142-vx3rgs4r	90	21	myocyte	myocyte	NNP
cord-017142-vx3rgs4r	90	22	hypertrophy	hypertrophy	NN
cord-017142-vx3rgs4r	90	23	)	)	-RRB-
cord-017142-vx3rgs4r	90	24	defined	define	VBN
cord-017142-vx3rgs4r	90	25	as	as	IN
cord-017142-vx3rgs4r	90	26	a	a	DT
cord-017142-vx3rgs4r	90	27	QRS	qrs	NN
cord-017142-vx3rgs4r	90	28	voltage	voltage	NN
cord-017142-vx3rgs4r	90	29	amplitude	amplitude	NN
cord-017142-vx3rgs4r	90	30	of	of	IN
cord-017142-vx3rgs4r	90	31	0.5	0.5	CD
cord-017142-vx3rgs4r	90	32	mV	mv	NN
cord-017142-vx3rgs4r	90	33	in	in	IN
cord-017142-vx3rgs4r	90	34	all	all	DT
cord-017142-vx3rgs4r	90	35	limb	limb	NN
cord-017142-vx3rgs4r	90	36	leads	lead	VBZ
cord-017142-vx3rgs4r	90	37	or	or	CC
cord-017142-vx3rgs4r	90	38	1	1	CD
cord-017142-vx3rgs4r	90	39	mV	mV	NNS
cord-017142-vx3rgs4r	90	40	in	in	IN
cord-017142-vx3rgs4r	90	41	all	all	DT
cord-017142-vx3rgs4r	90	42	precordial	precordial	JJ
cord-017142-vx3rgs4r	90	43	leads	lead	NNS
cord-017142-vx3rgs4r	90	44	(	(	-LRB-
cord-017142-vx3rgs4r	90	45	sensitivity	sensitivity	NN
cord-017142-vx3rgs4r	90	46	45	45	CD
cord-017142-vx3rgs4r	90	47	-	-	SYM
cord-017142-vx3rgs4r	90	48	70	70	CD
cord-017142-vx3rgs4r	90	49	%	%	NN
cord-017142-vx3rgs4r	90	50	)	)	-RRB-
cord-017142-vx3rgs4r	90	51	.	.	.
cord-017142-vx3rgs4r	91	1	This	this	DT
cord-017142-vx3rgs4r	91	2	may	may	MD
cord-017142-vx3rgs4r	91	3	be	be	VB
cord-017142-vx3rgs4r	91	4	described	describe	VBN
cord-017142-vx3rgs4r	91	5	as	as	IN
cord-017142-vx3rgs4r	91	6	a	a	DT
cord-017142-vx3rgs4r	91	7	pseudo	pseudo	JJ
cord-017142-vx3rgs4r	91	8	-	-	JJ
cord-017142-vx3rgs4r	91	9	infarct	infarct	JJ
cord-017142-vx3rgs4r	91	10	pattern	pattern	NN
cord-017142-vx3rgs4r	91	11	(	(	-LRB-
cord-017142-vx3rgs4r	91	12	50	50	CD
cord-017142-vx3rgs4r	91	13	-	-	SYM
cord-017142-vx3rgs4r	91	14	75	75	CD
cord-017142-vx3rgs4r	91	15	%	%	NN
cord-017142-vx3rgs4r	91	16	)	)	-RRB-
cord-017142-vx3rgs4r	91	17	.	.	.
cord-017142-vx3rgs4r	92	1	Atrioventricular	atrioventricular	JJ
cord-017142-vx3rgs4r	92	2	right	right	NN
cord-017142-vx3rgs4r	92	3	-	-	HYPH
cord-017142-vx3rgs4r	92	4	or	or	CC
cord-017142-vx3rgs4r	92	5	left	left	JJ
cord-017142-vx3rgs4r	92	6	-	-	HYPH
cord-017142-vx3rgs4r	92	7	bundle	bundle	NN
cord-017142-vx3rgs4r	92	8	branch	branch	NN
cord-017142-vx3rgs4r	92	9	blocks	block	NNS
cord-017142-vx3rgs4r	92	10	may	may	MD
cord-017142-vx3rgs4r	92	11	also	also	RB
cord-017142-vx3rgs4r	92	12	suggest	suggest	VB
cord-017142-vx3rgs4r	92	13	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	92	14	amyloid	amyloid	NN
cord-017142-vx3rgs4r	92	15	.	.	.
cord-017142-vx3rgs4r	93	1	Echocardiography	echocardiography	NN
cord-017142-vx3rgs4r	93	2	in	in	IN
cord-017142-vx3rgs4r	93	3	advanced	advanced	JJ
cord-017142-vx3rgs4r	93	4	stages	stage	NNS
cord-017142-vx3rgs4r	93	5	usually	usually	RB
cord-017142-vx3rgs4r	93	6	demonstrates	demonstrate	VBZ
cord-017142-vx3rgs4r	93	7	a	a	DT
cord-017142-vx3rgs4r	93	8	restrictive	restrictive	JJ
cord-017142-vx3rgs4r	93	9	pattern	pattern	NN
cord-017142-vx3rgs4r	93	10	due	due	IN
cord-017142-vx3rgs4r	93	11	to	to	IN
cord-017142-vx3rgs4r	93	12	the	the	DT
cord-017142-vx3rgs4r	93	13	structural	structural	JJ
cord-017142-vx3rgs4r	93	14	changes	change	NNS
cord-017142-vx3rgs4r	93	15	and	and	CC
cord-017142-vx3rgs4r	93	16	increased	increase	VBN
cord-017142-vx3rgs4r	93	17	echogenicity	echogenicity	NN
cord-017142-vx3rgs4r	93	18	of	of	IN
cord-017142-vx3rgs4r	93	19	the	the	DT
cord-017142-vx3rgs4r	93	20	myocardium	myocardium	NN
cord-017142-vx3rgs4r	93	21	with	with	IN
cord-017142-vx3rgs4r	93	22	a	a	DT
cord-017142-vx3rgs4r	93	23	"	"	``
cord-017142-vx3rgs4r	93	24	granular	granular	JJ
cord-017142-vx3rgs4r	93	25	speckling	speckling	NN
cord-017142-vx3rgs4r	93	26	"	"	''
cord-017142-vx3rgs4r	93	27	(	(	-LRB-
cord-017142-vx3rgs4r	93	28	low	low	JJ
cord-017142-vx3rgs4r	93	29	sensitivity	sensitivity	NN
cord-017142-vx3rgs4r	93	30	of	of	IN
cord-017142-vx3rgs4r	93	31	26	26	CD
cord-017142-vx3rgs4r	93	32	-	-	SYM
cord-017142-vx3rgs4r	93	33	36	36	CD
cord-017142-vx3rgs4r	93	34	%	%	NN
cord-017142-vx3rgs4r	93	35	but	but	CC
cord-017142-vx3rgs4r	93	36	with	with	IN
cord-017142-vx3rgs4r	93	37	a	a	DT
cord-017142-vx3rgs4r	93	38	high	high	JJ
cord-017142-vx3rgs4r	93	39	specificity	specificity	NN
cord-017142-vx3rgs4r	93	40	(	(	-LRB-
cord-017142-vx3rgs4r	93	41	71	71	CD
cord-017142-vx3rgs4r	93	42	-	-	SYM
cord-017142-vx3rgs4r	93	43	81	81	CD
cord-017142-vx3rgs4r	93	44	%	%	NN
cord-017142-vx3rgs4r	93	45	)	)	-RRB-
cord-017142-vx3rgs4r	93	46	)	)	-RRB-
cord-017142-vx3rgs4r	93	47	.	.	.
cord-017142-vx3rgs4r	94	1	Cardiac	Cardiac	NNP
cord-017142-vx3rgs4r	94	2	MRI	MRI	NNP
cord-017142-vx3rgs4r	94	3	in	in	IN
cord-017142-vx3rgs4r	94	4	advanced	advanced	JJ
cord-017142-vx3rgs4r	94	5	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	94	6	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	94	7	shows	show	NNS
cord-017142-vx3rgs4r	94	8	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	94	9	subendocardial	subendocardial	JJ
cord-017142-vx3rgs4r	94	10	heterogeneous	heterogeneous	JJ
cord-017142-vx3rgs4r	94	11	enhancement	enhancement	NN
cord-017142-vx3rgs4r	94	12	in	in	IN
cord-017142-vx3rgs4r	94	13	a	a	DT
cord-017142-vx3rgs4r	94	14	nonvascular	nonvascular	JJ
cord-017142-vx3rgs4r	94	15	distribution	distribution	NN
cord-017142-vx3rgs4r	94	16	on	on	IN
cord-017142-vx3rgs4r	94	17	delayed	delay	VBN
cord-017142-vx3rgs4r	94	18	contrast	contrast	NN
cord-017142-vx3rgs4r	94	19	-	-	HYPH
cord-017142-vx3rgs4r	94	20	enhanced	enhance	VBN
cord-017142-vx3rgs4r	94	21	MR	MR	NNP
cord-017142-vx3rgs4r	94	22	images	image	NNS
cord-017142-vx3rgs4r	94	23	using	use	VBG
cord-017142-vx3rgs4r	94	24	inversion	inversion	NN
cord-017142-vx3rgs4r	94	25	recovery	recovery	NN
cord-017142-vx3rgs4r	94	26	technique	technique	NN
cord-017142-vx3rgs4r	94	27	.	.	.
cord-017142-vx3rgs4r	95	1	This	this	DT
cord-017142-vx3rgs4r	95	2	,	,	,
cord-017142-vx3rgs4r	95	3	along	along	IN
cord-017142-vx3rgs4r	95	4	with	with	IN
cord-017142-vx3rgs4r	95	5	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	95	6	multichambered	multichambered	JJ
cord-017142-vx3rgs4r	95	7	wall	wall	NN
cord-017142-vx3rgs4r	95	8	thickening	thickening	NN
cord-017142-vx3rgs4r	95	9	,	,	,
cord-017142-vx3rgs4r	95	10	posterior	posterior	JJ
cord-017142-vx3rgs4r	95	11	right	right	JJ
cord-017142-vx3rgs4r	95	12	atrial	atrial	JJ
cord-017142-vx3rgs4r	95	13	wall	wall	NN
cord-017142-vx3rgs4r	95	14	thickening	thickening	NN
cord-017142-vx3rgs4r	95	15	,	,	,
cord-017142-vx3rgs4r	95	16	or	or	CC
cord-017142-vx3rgs4r	95	17	interatrial	interatrial	JJ
cord-017142-vx3rgs4r	95	18	septal	septal	JJ
cord-017142-vx3rgs4r	95	19	thickening	thickening	NN
cord-017142-vx3rgs4r	95	20	>	>	XX
cord-017142-vx3rgs4r	95	21	6	6	CD
cord-017142-vx3rgs4r	95	22	mm	mm	NN
cord-017142-vx3rgs4r	95	23	,	,	,
cord-017142-vx3rgs4r	95	24	is	be	VBZ
cord-017142-vx3rgs4r	95	25	specific	specific	JJ
cord-017142-vx3rgs4r	95	26	to	to	IN
cord-017142-vx3rgs4r	95	27	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	95	28	[	[	-LRB-
cord-017142-vx3rgs4r	95	29	10	10	CD
cord-017142-vx3rgs4r	95	30	,	,	,
cord-017142-vx3rgs4r	95	31	112	112	CD
cord-017142-vx3rgs4r	95	32	,	,	,
cord-017142-vx3rgs4r	95	33	126	126	CD
cord-017142-vx3rgs4r	95	34	]	]	-RRB-
cord-017142-vx3rgs4r	95	35	.	.	.
cord-017142-vx3rgs4r	96	1	Cardiac	cardiac	JJ
cord-017142-vx3rgs4r	96	2	catheterization	catheterization	NN
cord-017142-vx3rgs4r	96	3	is	be	VBZ
cord-017142-vx3rgs4r	96	4	not	not	RB
cord-017142-vx3rgs4r	96	5	always	always	RB
cord-017142-vx3rgs4r	96	6	required	require	VBN
cord-017142-vx3rgs4r	96	7	but	but	CC
cord-017142-vx3rgs4r	96	8	used	use	VBD
cord-017142-vx3rgs4r	96	9	to	to	TO
cord-017142-vx3rgs4r	96	10	obtain	obtain	VB
cord-017142-vx3rgs4r	96	11	endomyocardial	endomyocardial	JJ
cord-017142-vx3rgs4r	96	12	biopsy	biopsy	NN
cord-017142-vx3rgs4r	96	13	.	.	.
cord-017142-vx3rgs4r	97	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	97	2	may	may	MD
cord-017142-vx3rgs4r	97	3	help	help	VB
cord-017142-vx3rgs4r	97	4	to	to	TO
cord-017142-vx3rgs4r	97	5	provide	provide	VB
cord-017142-vx3rgs4r	97	6	important	important	JJ
cord-017142-vx3rgs4r	97	7	information	information	NN
cord-017142-vx3rgs4r	97	8	for	for	IN
cord-017142-vx3rgs4r	97	9	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	97	10	hemodynamics	hemodynamic	NNS
cord-017142-vx3rgs4r	97	11	,	,	,
cord-017142-vx3rgs4r	97	12	which	which	WDT
cord-017142-vx3rgs4r	97	13	generally	generally	RB
cord-017142-vx3rgs4r	97	14	shows	show	VBZ
cord-017142-vx3rgs4r	97	15	impaired	impaired	JJ
cord-017142-vx3rgs4r	97	16	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	97	17	filling	fill	VBG
cord-017142-vx3rgs4r	97	18	with	with	IN
cord-017142-vx3rgs4r	97	19	an	an	DT
cord-017142-vx3rgs4r	97	20	elevated	elevated	JJ
cord-017142-vx3rgs4r	97	21	left	left	JJ
cord-017142-vx3rgs4r	97	22	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	97	23	end	end	NN
cord-017142-vx3rgs4r	97	24	-	-	HYPH
cord-017142-vx3rgs4r	97	25	diastolic	diastolic	JJ
cord-017142-vx3rgs4r	97	26	pressure	pressure	NN
cord-017142-vx3rgs4r	97	27	.	.	.
cord-017142-vx3rgs4r	98	1	Demonstration	demonstration	NN
cord-017142-vx3rgs4r	98	2	of	of	IN
cord-017142-vx3rgs4r	98	3	left	left	JJ
cord-017142-vx3rgs4r	98	4	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	98	5	diastolic	diastolic	JJ
cord-017142-vx3rgs4r	98	6	pressure	pressure	NN
cord-017142-vx3rgs4r	98	7	greater	great	JJR
cord-017142-vx3rgs4r	98	8	than	than	IN
cord-017142-vx3rgs4r	98	9	right	right	JJ
cord-017142-vx3rgs4r	98	10	remains	remain	VBZ
cord-017142-vx3rgs4r	98	11	to	to	TO
cord-017142-vx3rgs4r	98	12	distinguish	distinguish	VB
cord-017142-vx3rgs4r	98	13	restrictive	restrictive	JJ
cord-017142-vx3rgs4r	98	14	cardiomyopathy	cardiomyopathy	NN
cord-017142-vx3rgs4r	98	15	from	from	IN
cord-017142-vx3rgs4r	98	16	its	-PRON-	PRP$
cord-017142-vx3rgs4r	98	17	differential	differential	JJ
cord-017142-vx3rgs4r	98	18	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	98	19	of	of	IN
cord-017142-vx3rgs4r	98	20	constrictive	constrictive	JJ
cord-017142-vx3rgs4r	98	21	pericarditis	pericarditis	NN
cord-017142-vx3rgs4r	98	22	.	.	.
cord-017142-vx3rgs4r	99	1	Fine	fine	JJ
cord-017142-vx3rgs4r	99	2	-	-	HYPH
cord-017142-vx3rgs4r	99	3	needle	needle	NN
cord-017142-vx3rgs4r	99	4	aspiration	aspiration	NN
cord-017142-vx3rgs4r	99	5	of	of	IN
cord-017142-vx3rgs4r	99	6	abdominal	abdominal	JJ
cord-017142-vx3rgs4r	99	7	fat	fat	NN
cord-017142-vx3rgs4r	99	8	is	be	VBZ
cord-017142-vx3rgs4r	99	9	relatively	relatively	RB
cord-017142-vx3rgs4r	99	10	sensitive	sensitive	JJ
cord-017142-vx3rgs4r	99	11	for	for	IN
cord-017142-vx3rgs4r	99	12	amyloid	amyloid	NN
cord-017142-vx3rgs4r	99	13	deposits	deposit	NNS
cord-017142-vx3rgs4r	99	14	(	(	-LRB-
cord-017142-vx3rgs4r	99	15	>	>	XX
cord-017142-vx3rgs4r	100	1	70	70	CD
cord-017142-vx3rgs4r	100	2	%	%	NN
cord-017142-vx3rgs4r	100	3	of	of	IN
cord-017142-vx3rgs4r	100	4	patients	patient	NNS
cord-017142-vx3rgs4r	100	5	with	with	IN
cord-017142-vx3rgs4r	100	6	AL	AL	NNP
cord-017142-vx3rgs4r	100	7	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	100	8	)	)	-RRB-
cord-017142-vx3rgs4r	101	1	;	;	:
cord-017142-vx3rgs4r	101	2	other	other	JJ
cord-017142-vx3rgs4r	101	3	sites	site	NNS
cord-017142-vx3rgs4r	101	4	of	of	IN
cord-017142-vx3rgs4r	101	5	amyloid	amyloid	NN
cord-017142-vx3rgs4r	101	6	deposition	deposition	NN
cord-017142-vx3rgs4r	101	7	include	include	VBP
cord-017142-vx3rgs4r	101	8	minor	minor	JJ
cord-017142-vx3rgs4r	101	9	salivary	salivary	NN
cord-017142-vx3rgs4r	101	10	glands	gland	NNS
cord-017142-vx3rgs4r	101	11	,	,	,
cord-017142-vx3rgs4r	101	12	gingiva	gingiva	NN
cord-017142-vx3rgs4r	101	13	,	,	,
cord-017142-vx3rgs4r	101	14	and	and	CC
cord-017142-vx3rgs4r	101	15	rectum	rectum	NN
cord-017142-vx3rgs4r	101	16	[	[	-LRB-
cord-017142-vx3rgs4r	101	17	3	3	CD
cord-017142-vx3rgs4r	101	18	,	,	,
cord-017142-vx3rgs4r	101	19	69	69	CD
cord-017142-vx3rgs4r	101	20	]	]	-RRB-
cord-017142-vx3rgs4r	101	21	.	.	.
cord-017142-vx3rgs4r	102	1	In	in	IN
cord-017142-vx3rgs4r	102	2	a	a	DT
cord-017142-vx3rgs4r	102	3	patient	patient	NN
cord-017142-vx3rgs4r	102	4	with	with	IN
cord-017142-vx3rgs4r	102	5	clinical	clinical	JJ
cord-017142-vx3rgs4r	102	6	suspicion	suspicion	NN
cord-017142-vx3rgs4r	102	7	of	of	IN
cord-017142-vx3rgs4r	102	8	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	102	9	involvement	involvement	NN
cord-017142-vx3rgs4r	102	10	,	,	,
cord-017142-vx3rgs4r	102	11	the	the	DT
cord-017142-vx3rgs4r	102	12	presence	presence	NN
cord-017142-vx3rgs4r	102	13	of	of	IN
cord-017142-vx3rgs4r	102	14	physical	physical	JJ
cord-017142-vx3rgs4r	102	15	exam	exam	NN
cord-017142-vx3rgs4r	102	16	findings	finding	NNS
cord-017142-vx3rgs4r	102	17	,	,	,
cord-017142-vx3rgs4r	102	18	blood	blood	NN
cord-017142-vx3rgs4r	102	19	markers	marker	NNS
cord-017142-vx3rgs4r	102	20	,	,	,
cord-017142-vx3rgs4r	102	21	imaging	imaging	NN
cord-017142-vx3rgs4r	102	22	,	,	,
cord-017142-vx3rgs4r	102	23	and	and	CC
cord-017142-vx3rgs4r	102	24	a	a	DT
cord-017142-vx3rgs4r	102	25	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	102	26	biopsy	biopsy	NN
cord-017142-vx3rgs4r	102	27	consistent	consistent	JJ
cord-017142-vx3rgs4r	102	28	with	with	IN
cord-017142-vx3rgs4r	102	29	amyloid	amyloid	NN
cord-017142-vx3rgs4r	102	30	are	be	VBP
cord-017142-vx3rgs4r	102	31	adequate	adequate	JJ
cord-017142-vx3rgs4r	102	32	for	for	IN
cord-017142-vx3rgs4r	102	33	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	102	34	.	.	.
cord-017142-vx3rgs4r	103	1	Patients	patient	NNS
cord-017142-vx3rgs4r	103	2	presenting	present	VBG
cord-017142-vx3rgs4r	103	3	with	with	IN
cord-017142-vx3rgs4r	103	4	acute	acute	JJ
cord-017142-vx3rgs4r	103	5	heart	heart	NN
cord-017142-vx3rgs4r	103	6	failure	failure	NN
cord-017142-vx3rgs4r	103	7	in	in	IN
cord-017142-vx3rgs4r	103	8	AL	AL	NNP
cord-017142-vx3rgs4r	103	9	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	103	10	require	require	VBP
cord-017142-vx3rgs4r	103	11	intensive	intensive	JJ
cord-017142-vx3rgs4r	103	12	care	care	NN
cord-017142-vx3rgs4r	103	13	monitoring	monitoring	NN
cord-017142-vx3rgs4r	103	14	and	and	CC
cord-017142-vx3rgs4r	103	15	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	103	16	supportive	supportive	JJ
cord-017142-vx3rgs4r	103	17	care	care	NN
cord-017142-vx3rgs4r	103	18	.	.	.
cord-017142-vx3rgs4r	104	1	Diuresis	Diuresis	NNP
cord-017142-vx3rgs4r	104	2	is	be	VBZ
cord-017142-vx3rgs4r	104	3	the	the	DT
cord-017142-vx3rgs4r	104	4	key	key	NN
cord-017142-vx3rgs4r	104	5	and	and	CC
cord-017142-vx3rgs4r	104	6	is	be	VBZ
cord-017142-vx3rgs4r	104	7	probably	probably	RB
cord-017142-vx3rgs4r	104	8	the	the	DT
cord-017142-vx3rgs4r	104	9	only	only	JJ
cord-017142-vx3rgs4r	104	10	treatment	treatment	NN
cord-017142-vx3rgs4r	104	11	modality	modality	NN
cord-017142-vx3rgs4r	104	12	that	that	WDT
cord-017142-vx3rgs4r	104	13	can	can	MD
cord-017142-vx3rgs4r	104	14	improve	improve	VB
cord-017142-vx3rgs4r	104	15	hemodynamics	hemodynamic	NNS
cord-017142-vx3rgs4r	104	16	.	.	.
cord-017142-vx3rgs4r	105	1	Optimal	optimal	JJ
cord-017142-vx3rgs4r	105	2	therapy	therapy	NN
cord-017142-vx3rgs4r	105	3	usually	usually	RB
cord-017142-vx3rgs4r	105	4	requires	require	VBZ
cord-017142-vx3rgs4r	105	5	using	use	VBG
cord-017142-vx3rgs4r	105	6	higher	high	JJR
cord-017142-vx3rgs4r	105	7	doses	dose	NNS
cord-017142-vx3rgs4r	105	8	of	of	IN
cord-017142-vx3rgs4r	105	9	diuretics	diuretic	NNS
cord-017142-vx3rgs4r	105	10	or	or	CC
cord-017142-vx3rgs4r	105	11	in	in	IN
cord-017142-vx3rgs4r	105	12	combinations	combination	NNS
cord-017142-vx3rgs4r	105	13	(	(	-LRB-
cord-017142-vx3rgs4r	105	14	furosemide	furosemide	NN
cord-017142-vx3rgs4r	105	15	,	,	,
cord-017142-vx3rgs4r	105	16	torsemide	torsemide	NNP
cord-017142-vx3rgs4r	105	17	,	,	,
cord-017142-vx3rgs4r	105	18	spironolactone	spironolactone	NNP
cord-017142-vx3rgs4r	105	19	,	,	,
cord-017142-vx3rgs4r	105	20	and	and	CC
cord-017142-vx3rgs4r	105	21	metolazone	metolazone	NNP
cord-017142-vx3rgs4r	105	22	)	)	-RRB-
cord-017142-vx3rgs4r	105	23	to	to	TO
cord-017142-vx3rgs4r	105	24	maintain	maintain	VB
cord-017142-vx3rgs4r	105	25	adequate	adequate	JJ
cord-017142-vx3rgs4r	105	26	diuresis	diuresis	NN
cord-017142-vx3rgs4r	105	27	,	,	,
cord-017142-vx3rgs4r	105	28	especially	especially	RB
cord-017142-vx3rgs4r	105	29	in	in	IN
cord-017142-vx3rgs4r	105	30	the	the	DT
cord-017142-vx3rgs4r	105	31	setting	setting	NN
cord-017142-vx3rgs4r	105	32	of	of	IN
cord-017142-vx3rgs4r	105	33	nephrotic	nephrotic	JJ
cord-017142-vx3rgs4r	105	34	syndrome	syndrome	NN
cord-017142-vx3rgs4r	105	35	.	.	.
cord-017142-vx3rgs4r	106	1	An	an	DT
cord-017142-vx3rgs4r	106	2	intravenous	intravenous	JJ
cord-017142-vx3rgs4r	106	3	route	route	NN
cord-017142-vx3rgs4r	106	4	is	be	VBZ
cord-017142-vx3rgs4r	106	5	likely	likely	RB
cord-017142-vx3rgs4r	106	6	preferred	prefer	VBN
cord-017142-vx3rgs4r	106	7	in	in	IN
cord-017142-vx3rgs4r	106	8	the	the	DT
cord-017142-vx3rgs4r	106	9	acute	acute	JJ
cord-017142-vx3rgs4r	106	10	stage	stage	NN
cord-017142-vx3rgs4r	106	11	,	,	,
cord-017142-vx3rgs4r	106	12	due	due	IN
cord-017142-vx3rgs4r	106	13	to	to	IN
cord-017142-vx3rgs4r	106	14	the	the	DT
cord-017142-vx3rgs4r	106	15	often	often	RB
cord-017142-vx3rgs4r	106	16	-	-	HYPH
cord-017142-vx3rgs4r	106	17	present	present	JJ
cord-017142-vx3rgs4r	106	18	gut	gut	NN
cord-017142-vx3rgs4r	106	19	edema	edema	NN
cord-017142-vx3rgs4r	106	20	and	and	CC
cord-017142-vx3rgs4r	106	21	better	well	JJR
cord-017142-vx3rgs4r	106	22	bioavailability	bioavailability	NN
cord-017142-vx3rgs4r	106	23	.	.	.
cord-017142-vx3rgs4r	107	1	Aggressive	aggressive	JJ
cord-017142-vx3rgs4r	107	2	supportive	supportive	JJ
cord-017142-vx3rgs4r	107	3	care	care	NN
cord-017142-vx3rgs4r	107	4	includes	include	VBZ
cord-017142-vx3rgs4r	107	5	maintaining	maintain	VBG
cord-017142-vx3rgs4r	107	6	strict	strict	JJ
cord-017142-vx3rgs4r	107	7	intake	intake	NN
cord-017142-vx3rgs4r	107	8	output	output	NN
cord-017142-vx3rgs4r	107	9	measurements	measurement	NNS
cord-017142-vx3rgs4r	107	10	,	,	,
cord-017142-vx3rgs4r	107	11	dietary	dietary	JJ
cord-017142-vx3rgs4r	107	12	salt	salt	NN
cord-017142-vx3rgs4r	107	13	restriction	restriction	NN
cord-017142-vx3rgs4r	107	14	,	,	,
cord-017142-vx3rgs4r	107	15	measuring	measure	VBG
cord-017142-vx3rgs4r	107	16	daily	daily	JJ
cord-017142-vx3rgs4r	107	17	weights	weight	NNS
cord-017142-vx3rgs4r	107	18	,	,	,
cord-017142-vx3rgs4r	107	19	and	and	CC
cord-017142-vx3rgs4r	107	20	monitoring	monitor	VBG
cord-017142-vx3rgs4r	107	21	for	for	IN
cord-017142-vx3rgs4r	107	22	arrhythmias	arrhythmia	NNS
cord-017142-vx3rgs4r	107	23	.	.	.
cord-017142-vx3rgs4r	108	1	The	the	DT
cord-017142-vx3rgs4r	108	2	uses	use	NNS
cord-017142-vx3rgs4r	108	3	of	of	IN
cord-017142-vx3rgs4r	108	4	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	108	5	protective	protective	JJ
cord-017142-vx3rgs4r	108	6	drugs	drug	NNS
cord-017142-vx3rgs4r	108	7	such	such	JJ
cord-017142-vx3rgs4r	108	8	as	as	IN
cord-017142-vx3rgs4r	108	9	beta	beta	NN
cord-017142-vx3rgs4r	108	10	-	-	HYPH
cord-017142-vx3rgs4r	108	11	blockers	blocker	NNS
cord-017142-vx3rgs4r	108	12	should	should	MD
cord-017142-vx3rgs4r	108	13	be	be	VB
cord-017142-vx3rgs4r	108	14	reserved	reserve	VBN
cord-017142-vx3rgs4r	108	15	for	for	IN
cord-017142-vx3rgs4r	108	16	cases	case	NNS
cord-017142-vx3rgs4r	108	17	of	of	IN
cord-017142-vx3rgs4r	108	18	atrial	atrial	JJ
cord-017142-vx3rgs4r	108	19	fibrillation	fibrillation	NN
cord-017142-vx3rgs4r	108	20	to	to	TO
cord-017142-vx3rgs4r	108	21	maintain	maintain	VB
cord-017142-vx3rgs4r	108	22	adequate	adequate	JJ
cord-017142-vx3rgs4r	108	23	filling	filling	NN
cord-017142-vx3rgs4r	108	24	pressure	pressure	NN
cord-017142-vx3rgs4r	108	25	.	.	.
cord-017142-vx3rgs4r	109	1	In	in	IN
cord-017142-vx3rgs4r	109	2	patients	patient	NNS
cord-017142-vx3rgs4r	109	3	without	without	IN
cord-017142-vx3rgs4r	109	4	AF	AF	NNP
cord-017142-vx3rgs4r	109	5	,	,	,
cord-017142-vx3rgs4r	109	6	its	-PRON-	PRP$
cord-017142-vx3rgs4r	109	7	use	use	NN
cord-017142-vx3rgs4r	109	8	should	should	MD
cord-017142-vx3rgs4r	109	9	be	be	VB
cord-017142-vx3rgs4r	109	10	discussed	discuss	VBN
cord-017142-vx3rgs4r	109	11	on	on	IN
cord-017142-vx3rgs4r	109	12	a	a	DT
cord-017142-vx3rgs4r	109	13	case	case	NN
cord-017142-vx3rgs4r	109	14	-	-	HYPH
cord-017142-vx3rgs4r	109	15	by	by	IN
cord-017142-vx3rgs4r	109	16	-	-	HYPH
cord-017142-vx3rgs4r	109	17	case	case	NN
cord-017142-vx3rgs4r	109	18	basis	basis	NN
cord-017142-vx3rgs4r	109	19	,	,	,
cord-017142-vx3rgs4r	109	20	considering	consider	VBG
cord-017142-vx3rgs4r	109	21	the	the	DT
cord-017142-vx3rgs4r	109	22	significant	significant	JJ
cord-017142-vx3rgs4r	109	23	risks	risk	NNS
cord-017142-vx3rgs4r	109	24	including	include	VBG
cord-017142-vx3rgs4r	109	25	labile	labile	JJ
cord-017142-vx3rgs4r	109	26	blood	blood	NN
cord-017142-vx3rgs4r	109	27	pressure	pressure	NN
cord-017142-vx3rgs4r	109	28	due	due	IN
cord-017142-vx3rgs4r	109	29	to	to	IN
cord-017142-vx3rgs4r	109	30	autonomic	autonomic	JJ
cord-017142-vx3rgs4r	109	31	neuropathy	neuropathy	NN
cord-017142-vx3rgs4r	109	32	and	and	CC
cord-017142-vx3rgs4r	109	33	risk	risk	NN
cord-017142-vx3rgs4r	109	34	of	of	IN
cord-017142-vx3rgs4r	109	35	bradycardia	bradycardia	NN
cord-017142-vx3rgs4r	109	36	due	due	IN
cord-017142-vx3rgs4r	109	37	to	to	IN
cord-017142-vx3rgs4r	109	38	coexistent	coexistent	JJ
cord-017142-vx3rgs4r	109	39	conduction	conduction	NN
cord-017142-vx3rgs4r	109	40	defects	defect	NNS
cord-017142-vx3rgs4r	109	41	.	.	.
cord-017142-vx3rgs4r	110	1	Caution	caution	NN
cord-017142-vx3rgs4r	110	2	should	should	MD
cord-017142-vx3rgs4r	110	3	be	be	VB
cord-017142-vx3rgs4r	110	4	maintained	maintain	VBN
cord-017142-vx3rgs4r	110	5	with	with	IN
cord-017142-vx3rgs4r	110	6	the	the	DT
cord-017142-vx3rgs4r	110	7	use	use	NN
cord-017142-vx3rgs4r	110	8	of	of	IN
cord-017142-vx3rgs4r	110	9	angiotensin	angiotensin	NN
cord-017142-vx3rgs4r	110	10	-	-	HYPH
cord-017142-vx3rgs4r	110	11	converting	convert	VBG
cord-017142-vx3rgs4r	110	12	enzyme	enzyme	NN
cord-017142-vx3rgs4r	110	13	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	110	14	and	and	CC
cord-017142-vx3rgs4r	110	15	angiotensin	angiotensin	NN
cord-017142-vx3rgs4r	110	16	II	II	NNP
cord-017142-vx3rgs4r	110	17	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	110	18	,	,	,
cord-017142-vx3rgs4r	110	19	due	due	JJ
cord-017142-vx3rgs4r	110	20	to	to	IN
cord-017142-vx3rgs4r	110	21	similar	similar	JJ
cord-017142-vx3rgs4r	110	22	risk	risk	NN
cord-017142-vx3rgs4r	110	23	of	of	IN
cord-017142-vx3rgs4r	110	24	exacerbating	exacerbate	VBG
cord-017142-vx3rgs4r	110	25	hypotension	hypotension	NN
cord-017142-vx3rgs4r	110	26	.	.	.
cord-017142-vx3rgs4r	111	1	Both	both	DT
cord-017142-vx3rgs4r	111	2	digoxin	digoxin	NN
cord-017142-vx3rgs4r	111	3	and	and	CC
cord-017142-vx3rgs4r	111	4	calcium	calcium	NN
cord-017142-vx3rgs4r	111	5	blockers	blocker	NNS
cord-017142-vx3rgs4r	111	6	,	,	,
cord-017142-vx3rgs4r	111	7	especially	especially	RB
cord-017142-vx3rgs4r	111	8	nifedipine	nifedipine	NN
cord-017142-vx3rgs4r	111	9	,	,	,
cord-017142-vx3rgs4r	111	10	have	have	VBP
cord-017142-vx3rgs4r	111	11	the	the	DT
cord-017142-vx3rgs4r	111	12	tendency	tendency	NN
cord-017142-vx3rgs4r	111	13	to	to	TO
cord-017142-vx3rgs4r	111	14	bind	bind	VB
cord-017142-vx3rgs4r	111	15	to	to	IN
cord-017142-vx3rgs4r	111	16	amyloid	amyloid	NN
cord-017142-vx3rgs4r	111	17	fibrils	fibril	NNS
cord-017142-vx3rgs4r	111	18	.	.	.
cord-017142-vx3rgs4r	112	1	This	this	DT
cord-017142-vx3rgs4r	112	2	can	can	MD
cord-017142-vx3rgs4r	112	3	precipitate	precipitate	VB
cord-017142-vx3rgs4r	112	4	congestive	congestive	JJ
cord-017142-vx3rgs4r	112	5	heart	heart	NN
cord-017142-vx3rgs4r	112	6	failure	failure	NN
cord-017142-vx3rgs4r	112	7	due	due	JJ
cord-017142-vx3rgs4r	112	8	to	to	IN
cord-017142-vx3rgs4r	112	9	increased	increase	VBN
cord-017142-vx3rgs4r	112	10	susceptibility	susceptibility	NN
cord-017142-vx3rgs4r	112	11	to	to	IN
cord-017142-vx3rgs4r	112	12	digoxin	digoxin	NN
cord-017142-vx3rgs4r	112	13	toxicity	toxicity	NN
cord-017142-vx3rgs4r	112	14	and	and	CC
cord-017142-vx3rgs4r	112	15	enhance	enhance	VB
cord-017142-vx3rgs4r	112	16	the	the	DT
cord-017142-vx3rgs4r	112	17	negative	negative	JJ
cord-017142-vx3rgs4r	112	18	ionotropic	ionotropic	JJ
cord-017142-vx3rgs4r	112	19	effect	effect	NN
cord-017142-vx3rgs4r	112	20	with	with	IN
cord-017142-vx3rgs4r	112	21	calcium	calcium	NN
cord-017142-vx3rgs4r	112	22	channel	channel	NN
cord-017142-vx3rgs4r	112	23	blockers	blocker	NNS
cord-017142-vx3rgs4r	112	24	[	[	-LRB-
cord-017142-vx3rgs4r	112	25	41	41	CD
cord-017142-vx3rgs4r	112	26	,	,	,
cord-017142-vx3rgs4r	112	27	84	84	CD
cord-017142-vx3rgs4r	112	28	,	,	,
cord-017142-vx3rgs4r	112	29	107	107	CD
cord-017142-vx3rgs4r	112	30	]	]	-RRB-
cord-017142-vx3rgs4r	112	31	.	.	.
cord-017142-vx3rgs4r	113	1	Syncope	syncope	NN
cord-017142-vx3rgs4r	113	2	can	can	MD
cord-017142-vx3rgs4r	113	3	result	result	VB
cord-017142-vx3rgs4r	113	4	from	from	IN
cord-017142-vx3rgs4r	113	5	AF	AF	NNP
cord-017142-vx3rgs4r	113	6	with	with	IN
cord-017142-vx3rgs4r	113	7	rapid	rapid	JJ
cord-017142-vx3rgs4r	113	8	heart	heart	NN
cord-017142-vx3rgs4r	113	9	rate	rate	NN
cord-017142-vx3rgs4r	113	10	,	,	,
cord-017142-vx3rgs4r	113	11	embolic	embolic	JJ
cord-017142-vx3rgs4r	113	12	phenomenon	phenomenon	NN
cord-017142-vx3rgs4r	113	13	,	,	,
cord-017142-vx3rgs4r	113	14	conduction	conduction	NN
cord-017142-vx3rgs4r	113	15	defects	defect	NNS
cord-017142-vx3rgs4r	113	16	,	,	,
cord-017142-vx3rgs4r	113	17	bradycardia	bradycardia	NN
cord-017142-vx3rgs4r	113	18	,	,	,
cord-017142-vx3rgs4r	113	19	and	and	CC
cord-017142-vx3rgs4r	113	20	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	113	21	arrhythmias	arrhythmia	NNS
cord-017142-vx3rgs4r	113	22	.	.	.
cord-017142-vx3rgs4r	114	1	The	the	DT
cord-017142-vx3rgs4r	114	2	most	most	RBS
cord-017142-vx3rgs4r	114	3	common	common	JJ
cord-017142-vx3rgs4r	114	4	atrial	atrial	JJ
cord-017142-vx3rgs4r	114	5	arrhythmia	arrhythmia	NN
cord-017142-vx3rgs4r	114	6	(	(	-LRB-
cord-017142-vx3rgs4r	114	7	10	10	CD
cord-017142-vx3rgs4r	114	8	-	-	SYM
cord-017142-vx3rgs4r	114	9	15	15	CD
cord-017142-vx3rgs4r	114	10	%	%	NN
cord-017142-vx3rgs4r	114	11	of	of	IN
cord-017142-vx3rgs4r	114	12	patients	patient	NNS
cord-017142-vx3rgs4r	114	13	)	)	-RRB-
cord-017142-vx3rgs4r	114	14	is	be	VBZ
cord-017142-vx3rgs4r	114	15	AF	AF	NNP
cord-017142-vx3rgs4r	114	16	and	and	CC
cord-017142-vx3rgs4r	114	17	is	be	VBZ
cord-017142-vx3rgs4r	114	18	associated	associate	VBN
cord-017142-vx3rgs4r	114	19	with	with	IN
cord-017142-vx3rgs4r	114	20	a	a	DT
cord-017142-vx3rgs4r	114	21	very	very	RB
cord-017142-vx3rgs4r	114	22	high	high	JJ
cord-017142-vx3rgs4r	114	23	incidence	incidence	NN
cord-017142-vx3rgs4r	114	24	of	of	IN
cord-017142-vx3rgs4r	114	25	thromboembolism	thromboembolism	NN
cord-017142-vx3rgs4r	114	26	.	.	.
cord-017142-vx3rgs4r	115	1	In	in	IN
cord-017142-vx3rgs4r	115	2	a	a	DT
cord-017142-vx3rgs4r	115	3	Mayo	Mayo	NNP
cord-017142-vx3rgs4r	115	4	Clinic	Clinic	NNP
cord-017142-vx3rgs4r	115	5	study	study	NN
cord-017142-vx3rgs4r	115	6	,	,	,
cord-017142-vx3rgs4r	115	7	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	115	8	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	115	9	patients	patient	NNS
cord-017142-vx3rgs4r	115	10	undergoing	undergo	VBG
cord-017142-vx3rgs4r	115	11	transesophageal	transesophageal	NN
cord-017142-vx3rgs4r	115	12	echocardiography	echocardiography	NN
cord-017142-vx3rgs4r	115	13	had	have	VBD
cord-017142-vx3rgs4r	115	14	a	a	DT
cord-017142-vx3rgs4r	115	15	higher	high	JJR
cord-017142-vx3rgs4r	115	16	frequency	frequency	NN
cord-017142-vx3rgs4r	115	17	of	of	IN
cord-017142-vx3rgs4r	115	18	intracardiac	intracardiac	NNP
cord-017142-vx3rgs4r	115	19	thrombus	thrombus	NN
cord-017142-vx3rgs4r	115	20	(	(	-LRB-
cord-017142-vx3rgs4r	115	21	35	35	CD
cord-017142-vx3rgs4r	115	22	%	%	NN
cord-017142-vx3rgs4r	115	23	)	)	-RRB-
cord-017142-vx3rgs4r	115	24	irrespective	irrespective	RB
cord-017142-vx3rgs4r	115	25	of	of	IN
cord-017142-vx3rgs4r	115	26	the	the	DT
cord-017142-vx3rgs4r	115	27	presence	presence	NN
cord-017142-vx3rgs4r	115	28	of	of	IN
cord-017142-vx3rgs4r	115	29	atrial	atrial	JJ
cord-017142-vx3rgs4r	115	30	fibrillation	fibrillation	NN
cord-017142-vx3rgs4r	115	31	.	.	.
cord-017142-vx3rgs4r	116	1	Factors	factor	NNS
cord-017142-vx3rgs4r	116	2	associated	associate	VBN
cord-017142-vx3rgs4r	116	3	with	with	IN
cord-017142-vx3rgs4r	116	4	increased	increase	VBN
cord-017142-vx3rgs4r	116	5	risk	risk	NN
cord-017142-vx3rgs4r	116	6	of	of	IN
cord-017142-vx3rgs4r	116	7	intracardiac	intracardiac	NNP
cord-017142-vx3rgs4r	116	8	thrombosis	thrombosis	NN
cord-017142-vx3rgs4r	116	9	include	include	VBP
cord-017142-vx3rgs4r	116	10	atrial	atrial	JJ
cord-017142-vx3rgs4r	116	11	fibrillation	fibrillation	NN
cord-017142-vx3rgs4r	116	12	,	,	,
cord-017142-vx3rgs4r	116	13	poor	poor	JJ
cord-017142-vx3rgs4r	116	14	left	leave	VBD
cord-017142-vx3rgs4r	116	15	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	116	16	diastolic	diastolic	JJ
cord-017142-vx3rgs4r	116	17	function	function	NN
cord-017142-vx3rgs4r	116	18	(	(	-LRB-
cord-017142-vx3rgs4r	116	19	grade	grade	NN
cord-017142-vx3rgs4r	116	20	3	3	CD
cord-017142-vx3rgs4r	116	21	or	or	CC
cord-017142-vx3rgs4r	116	22	4	4	CD
cord-017142-vx3rgs4r	116	23	)	)	-RRB-
cord-017142-vx3rgs4r	116	24	,	,	,
cord-017142-vx3rgs4r	116	25	lower	low	JJR
cord-017142-vx3rgs4r	116	26	left	left	JJ
cord-017142-vx3rgs4r	116	27	atrial	atrial	JJ
cord-017142-vx3rgs4r	116	28	appendage	appendage	NN
cord-017142-vx3rgs4r	116	29	emptying	empty	VBG
cord-017142-vx3rgs4r	116	30	velocity	velocity	NN
cord-017142-vx3rgs4r	116	31	(	(	-LRB-
cord-017142-vx3rgs4r	116	32	15	15	CD
cord-017142-vx3rgs4r	116	33	cm	cm	NNS
cord-017142-vx3rgs4r	116	34	/	/	SYM
cord-017142-vx3rgs4r	116	35	s	s	NN
cord-017142-vx3rgs4r	116	36	)	)	-RRB-
cord-017142-vx3rgs4r	116	37	,	,	,
cord-017142-vx3rgs4r	116	38	increased	increase	VBD
cord-017142-vx3rgs4r	116	39	RV	rv	NN
cord-017142-vx3rgs4r	116	40	wall	wall	NN
cord-017142-vx3rgs4r	116	41	thickness	thickness	NN
cord-017142-vx3rgs4r	116	42	,	,	,
cord-017142-vx3rgs4r	116	43	low	low	JJ
cord-017142-vx3rgs4r	116	44	systolic	systolic	JJ
cord-017142-vx3rgs4r	116	45	blood	blood	NN
cord-017142-vx3rgs4r	116	46	pressure	pressure	NN
cord-017142-vx3rgs4r	116	47	,	,	,
cord-017142-vx3rgs4r	116	48	and	and	CC
cord-017142-vx3rgs4r	116	49	increased	increase	VBN
cord-017142-vx3rgs4r	116	50	heart	heart	NN
cord-017142-vx3rgs4r	116	51	rate	rate	NN
cord-017142-vx3rgs4r	116	52	.	.	.
cord-017142-vx3rgs4r	117	1	This	this	DT
cord-017142-vx3rgs4r	117	2	group	group	NN
cord-017142-vx3rgs4r	117	3	of	of	IN
cord-017142-vx3rgs4r	117	4	patients	patient	NNS
cord-017142-vx3rgs4r	117	5	should	should	MD
cord-017142-vx3rgs4r	117	6	be	be	VB
cord-017142-vx3rgs4r	117	7	considered	consider	VBN
cord-017142-vx3rgs4r	117	8	high	high	JJ
cord-017142-vx3rgs4r	117	9	risk	risk	NN
cord-017142-vx3rgs4r	117	10	for	for	IN
cord-017142-vx3rgs4r	117	11	thromboembolic	thromboembolic	JJ
cord-017142-vx3rgs4r	117	12	events	event	NNS
cord-017142-vx3rgs4r	117	13	and	and	CC
cord-017142-vx3rgs4r	117	14	merits	merit	NNS
cord-017142-vx3rgs4r	117	15	screening	screening	NN
cord-017142-vx3rgs4r	117	16	with	with	IN
cord-017142-vx3rgs4r	117	17	TEE	tee	NN
cord-017142-vx3rgs4r	117	18	.	.	.
cord-017142-vx3rgs4r	118	1	Anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	118	2	should	should	MD
cord-017142-vx3rgs4r	118	3	be	be	VB
cord-017142-vx3rgs4r	118	4	strongly	strongly	RB
cord-017142-vx3rgs4r	118	5	considered	consider	VBN
cord-017142-vx3rgs4r	118	6	in	in	IN
cord-017142-vx3rgs4r	118	7	the	the	DT
cord-017142-vx3rgs4r	118	8	presence	presence	NN
cord-017142-vx3rgs4r	118	9	of	of	IN
cord-017142-vx3rgs4r	118	10	any	any	DT
cord-017142-vx3rgs4r	118	11	of	of	IN
cord-017142-vx3rgs4r	118	12	these	these	DT
cord-017142-vx3rgs4r	118	13	risk	risk	NN
cord-017142-vx3rgs4r	118	14	factors	factor	NNS
cord-017142-vx3rgs4r	118	15	due	due	JJ
cord-017142-vx3rgs4r	118	16	to	to	IN
cord-017142-vx3rgs4r	118	17	the	the	DT
cord-017142-vx3rgs4r	118	18	heightened	heightened	JJ
cord-017142-vx3rgs4r	118	19	risk	risk	NN
cord-017142-vx3rgs4r	118	20	for	for	IN
cord-017142-vx3rgs4r	118	21	mural	mural	JJ
cord-017142-vx3rgs4r	118	22	thrombus	thrombus	NN
cord-017142-vx3rgs4r	118	23	development	development	NN
cord-017142-vx3rgs4r	118	24	and	and	CC
cord-017142-vx3rgs4r	118	25	embolic	embolic	JJ
cord-017142-vx3rgs4r	118	26	events	event	NNS
cord-017142-vx3rgs4r	118	27	.	.	.
cord-017142-vx3rgs4r	119	1	This	this	DT
cord-017142-vx3rgs4r	119	2	should	should	MD
cord-017142-vx3rgs4r	119	3	be	be	VB
cord-017142-vx3rgs4r	119	4	weighed	weigh	VBN
cord-017142-vx3rgs4r	119	5	against	against	IN
cord-017142-vx3rgs4r	119	6	the	the	DT
cord-017142-vx3rgs4r	119	7	risk	risk	NN
cord-017142-vx3rgs4r	119	8	of	of	IN
cord-017142-vx3rgs4r	119	9	bleeding	bleed	VBG
cord-017142-vx3rgs4r	119	10	in	in	IN
cord-017142-vx3rgs4r	119	11	these	these	DT
cord-017142-vx3rgs4r	119	12	patients	patient	NNS
cord-017142-vx3rgs4r	119	13	due	due	JJ
cord-017142-vx3rgs4r	119	14	to	to	IN
cord-017142-vx3rgs4r	119	15	the	the	DT
cord-017142-vx3rgs4r	119	16	potential	potential	NN
cord-017142-vx3rgs4r	119	17	for	for	IN
cord-017142-vx3rgs4r	119	18	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	119	19	coagulopathy	coagulopathy	NN
cord-017142-vx3rgs4r	119	20	and	and	CC
cord-017142-vx3rgs4r	119	21	fragile	fragile	JJ
cord-017142-vx3rgs4r	119	22	vasculature	vasculature	NN
cord-017142-vx3rgs4r	119	23	[	[	-LRB-
cord-017142-vx3rgs4r	119	24	36	36	CD
cord-017142-vx3rgs4r	119	25	]	]	-RRB-
cord-017142-vx3rgs4r	119	26	.	.	.
cord-017142-vx3rgs4r	120	1	Pacemakers	pacemaker	NNS
cord-017142-vx3rgs4r	120	2	are	be	VBP
cord-017142-vx3rgs4r	120	3	a	a	DT
cord-017142-vx3rgs4r	120	4	consideration	consideration	NN
cord-017142-vx3rgs4r	120	5	in	in	IN
cord-017142-vx3rgs4r	120	6	the	the	DT
cord-017142-vx3rgs4r	120	7	presence	presence	NN
cord-017142-vx3rgs4r	120	8	of	of	IN
cord-017142-vx3rgs4r	120	9	heart	heart	NN
cord-017142-vx3rgs4r	120	10	block	block	NN
cord-017142-vx3rgs4r	120	11	or	or	CC
cord-017142-vx3rgs4r	120	12	symptomatic	symptomatic	JJ
cord-017142-vx3rgs4r	120	13	bradycardia	bradycardia	NN
cord-017142-vx3rgs4r	120	14	.	.	.
cord-017142-vx3rgs4r	121	1	The	the	DT
cord-017142-vx3rgs4r	121	2	role	role	NN
cord-017142-vx3rgs4r	121	3	of	of	IN
cord-017142-vx3rgs4r	121	4	intracardiac	intracardiac	NNP
cord-017142-vx3rgs4r	121	5	defibrillators	defibrillator	NNS
cord-017142-vx3rgs4r	121	6	is	be	VBZ
cord-017142-vx3rgs4r	121	7	controversial	controversial	JJ
cord-017142-vx3rgs4r	121	8	due	due	IN
cord-017142-vx3rgs4r	121	9	to	to	IN
cord-017142-vx3rgs4r	121	10	limited	limited	JJ
cord-017142-vx3rgs4r	121	11	evidence	evidence	NN
cord-017142-vx3rgs4r	121	12	showing	show	VBG
cord-017142-vx3rgs4r	121	13	a	a	DT
cord-017142-vx3rgs4r	121	14	survival	survival	NN
cord-017142-vx3rgs4r	121	15	benefit	benefit	NN
cord-017142-vx3rgs4r	121	16	both	both	DT
cord-017142-vx3rgs4r	121	17	for	for	IN
cord-017142-vx3rgs4r	121	18	primary	primary	JJ
cord-017142-vx3rgs4r	121	19	and	and	CC
cord-017142-vx3rgs4r	121	20	secondary	secondary	JJ
cord-017142-vx3rgs4r	121	21	prevention	prevention	NN
cord-017142-vx3rgs4r	121	22	.	.	.
cord-017142-vx3rgs4r	122	1	Several	several	JJ
cord-017142-vx3rgs4r	122	2	studies	study	NNS
cord-017142-vx3rgs4r	122	3	report	report	VBP
cord-017142-vx3rgs4r	122	4	ventricular	ventricular	JJ
cord-017142-vx3rgs4r	122	5	arrhythmias	arrhythmias	RB
cord-017142-vx3rgs4r	122	6	in	in	IN
cord-017142-vx3rgs4r	122	7	about	about	RB
cord-017142-vx3rgs4r	122	8	a	a	DT
cord-017142-vx3rgs4r	122	9	third	third	NN
cord-017142-vx3rgs4r	122	10	of	of	IN
cord-017142-vx3rgs4r	122	11	patients	patient	NNS
cord-017142-vx3rgs4r	122	12	;	;	:
cord-017142-vx3rgs4r	122	13	however	however	RB
cord-017142-vx3rgs4r	122	14	,	,	,
cord-017142-vx3rgs4r	122	15	this	this	DT
cord-017142-vx3rgs4r	122	16	does	do	VBZ
cord-017142-vx3rgs4r	122	17	not	not	RB
cord-017142-vx3rgs4r	122	18	appear	appear	VB
cord-017142-vx3rgs4r	122	19	to	to	TO
cord-017142-vx3rgs4r	122	20	be	be	VB
cord-017142-vx3rgs4r	122	21	the	the	DT
cord-017142-vx3rgs4r	122	22	leading	leading	JJ
cord-017142-vx3rgs4r	122	23	cause	cause	NN
cord-017142-vx3rgs4r	122	24	of	of	IN
cord-017142-vx3rgs4r	122	25	mortality	mortality	NN
cord-017142-vx3rgs4r	122	26	in	in	IN
cord-017142-vx3rgs4r	122	27	this	this	DT
cord-017142-vx3rgs4r	122	28	patient	patient	NN
cord-017142-vx3rgs4r	122	29	group	group	NN
cord-017142-vx3rgs4r	122	30	.	.	.
cord-017142-vx3rgs4r	123	1	Once	once	IN
cord-017142-vx3rgs4r	123	2	congestive	congestive	JJ
cord-017142-vx3rgs4r	123	3	heart	heart	NN
cord-017142-vx3rgs4r	123	4	failure	failure	NN
cord-017142-vx3rgs4r	123	5	occurs	occur	VBZ
cord-017142-vx3rgs4r	123	6	,	,	,
cord-017142-vx3rgs4r	123	7	the	the	DT
cord-017142-vx3rgs4r	123	8	clinical	clinical	JJ
cord-017142-vx3rgs4r	123	9	course	course	NN
cord-017142-vx3rgs4r	123	10	for	for	IN
cord-017142-vx3rgs4r	123	11	patients	patient	NNS
cord-017142-vx3rgs4r	123	12	rapidly	rapidly	RB
cord-017142-vx3rgs4r	123	13	deteriorates	deteriorate	VBZ
cord-017142-vx3rgs4r	123	14	,	,	,
cord-017142-vx3rgs4r	123	15	with	with	IN
cord-017142-vx3rgs4r	123	16	a	a	DT
cord-017142-vx3rgs4r	123	17	median	median	JJ
cord-017142-vx3rgs4r	123	18	survival	survival	NN
cord-017142-vx3rgs4r	123	19	of	of	IN
cord-017142-vx3rgs4r	123	20	6	6	CD
cord-017142-vx3rgs4r	123	21	-	-	SYM
cord-017142-vx3rgs4r	123	22	12	12	CD
cord-017142-vx3rgs4r	123	23	months	month	NNS
cord-017142-vx3rgs4r	123	24	from	from	IN
cord-017142-vx3rgs4r	123	25	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	123	26	.	.	.
cord-017142-vx3rgs4r	124	1	Death	death	NN
cord-017142-vx3rgs4r	124	2	in	in	IN
cord-017142-vx3rgs4r	124	3	severe	severe	JJ
cord-017142-vx3rgs4r	124	4	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	124	5	amyloid	amyloid	NN
cord-017142-vx3rgs4r	124	6	is	be	VBZ
cord-017142-vx3rgs4r	124	7	often	often	RB
cord-017142-vx3rgs4r	124	8	heralded	herald	VBN
cord-017142-vx3rgs4r	124	9	by	by	IN
cord-017142-vx3rgs4r	124	10	agonal	agonal	JJ
cord-017142-vx3rgs4r	124	11	bradycardia	bradycardia	NN
cord-017142-vx3rgs4r	124	12	,	,	,
cord-017142-vx3rgs4r	124	13	followed	follow	VBN
cord-017142-vx3rgs4r	124	14	by	by	IN
cord-017142-vx3rgs4r	124	15	electromechanical	electromechanical	JJ
cord-017142-vx3rgs4r	124	16	dissociation	dissociation	NN
cord-017142-vx3rgs4r	124	17	or	or	CC
cord-017142-vx3rgs4r	124	18	PEA	pea	NN
cord-017142-vx3rgs4r	124	19	.	.	.
cord-017142-vx3rgs4r	125	1	Nonetheless	nonetheless	RB
cord-017142-vx3rgs4r	125	2	consensus	consensus	NN
cord-017142-vx3rgs4r	125	3	guidelines	guideline	NNS
cord-017142-vx3rgs4r	125	4	do	do	VBP
cord-017142-vx3rgs4r	125	5	not	not	RB
cord-017142-vx3rgs4r	125	6	support	support	VB
cord-017142-vx3rgs4r	125	7	ICD	icd	NN
cord-017142-vx3rgs4r	125	8	placement	placement	NN
cord-017142-vx3rgs4r	125	9	for	for	IN
cord-017142-vx3rgs4r	125	10	primary	primary	JJ
cord-017142-vx3rgs4r	125	11	prevention	prevention	NN
cord-017142-vx3rgs4r	125	12	of	of	IN
cord-017142-vx3rgs4r	125	13	SCD	SCD	NNP
cord-017142-vx3rgs4r	125	14	in	in	IN
cord-017142-vx3rgs4r	125	15	patients	patient	NNS
cord-017142-vx3rgs4r	125	16	if	if	IN
cord-017142-vx3rgs4r	125	17	life	life	NN
cord-017142-vx3rgs4r	125	18	expectancy	expectancy	NN
cord-017142-vx3rgs4r	125	19	is	be	VBZ
cord-017142-vx3rgs4r	125	20	<	<	NNP
cord-017142-vx3rgs4r	125	21	1	1	CD
cord-017142-vx3rgs4r	125	22	year	year	NN
cord-017142-vx3rgs4r	125	23	.	.	.
cord-017142-vx3rgs4r	126	1	Hence	hence	RB
cord-017142-vx3rgs4r	126	2	these	these	DT
cord-017142-vx3rgs4r	126	3	devices	device	NNS
cord-017142-vx3rgs4r	126	4	have	have	VBP
cord-017142-vx3rgs4r	126	5	rarely	rarely	RB
cord-017142-vx3rgs4r	126	6	been	be	VBN
cord-017142-vx3rgs4r	126	7	used	use	VBN
cord-017142-vx3rgs4r	126	8	in	in	IN
cord-017142-vx3rgs4r	126	9	patients	patient	NNS
cord-017142-vx3rgs4r	126	10	with	with	IN
cord-017142-vx3rgs4r	126	11	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	126	12	AL	AL	NNP
cord-017142-vx3rgs4r	126	13	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	126	14	.	.	.
cord-017142-vx3rgs4r	127	1	With	with	IN
cord-017142-vx3rgs4r	127	2	improvement	improvement	NN
cord-017142-vx3rgs4r	127	3	in	in	IN
cord-017142-vx3rgs4r	127	4	the	the	DT
cord-017142-vx3rgs4r	127	5	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	127	6	platform	platform	NN
cord-017142-vx3rgs4r	127	7	of	of	IN
cord-017142-vx3rgs4r	127	8	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	127	9	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	127	10	and	and	CC
cord-017142-vx3rgs4r	127	11	improved	improved	JJ
cord-017142-vx3rgs4r	127	12	survival	survival	NN
cord-017142-vx3rgs4r	127	13	,	,	,
cord-017142-vx3rgs4r	127	14	it	-PRON-	PRP
cord-017142-vx3rgs4r	127	15	becomes	become	VBZ
cord-017142-vx3rgs4r	127	16	a	a	DT
cord-017142-vx3rgs4r	127	17	priority	priority	NN
cord-017142-vx3rgs4r	127	18	to	to	TO
cord-017142-vx3rgs4r	127	19	be	be	VB
cord-017142-vx3rgs4r	127	20	able	able	JJ
cord-017142-vx3rgs4r	127	21	to	to	TO
cord-017142-vx3rgs4r	127	22	select	select	VB
cord-017142-vx3rgs4r	127	23	the	the	DT
cord-017142-vx3rgs4r	127	24	patients	patient	NNS
cord-017142-vx3rgs4r	127	25	that	that	WDT
cord-017142-vx3rgs4r	127	26	benefit	benefit	VBP
cord-017142-vx3rgs4r	127	27	from	from	IN
cord-017142-vx3rgs4r	127	28	antiarrhythmic	antiarrhythmic	JJ
cord-017142-vx3rgs4r	127	29	prophylaxis	prophylaxis	NN
cord-017142-vx3rgs4r	127	30	and	and	CC
cord-017142-vx3rgs4r	127	31	primary	primary	JJ
cord-017142-vx3rgs4r	127	32	prevention	prevention	NN
cord-017142-vx3rgs4r	127	33	ICDs	icd	NNS
cord-017142-vx3rgs4r	127	34	.	.	.
cord-017142-vx3rgs4r	128	1	With	with	IN
cord-017142-vx3rgs4r	128	2	the	the	DT
cord-017142-vx3rgs4r	128	3	available	available	JJ
cord-017142-vx3rgs4r	128	4	data	datum	NNS
cord-017142-vx3rgs4r	128	5	,	,	,
cord-017142-vx3rgs4r	128	6	ICDs	ICDs	NNP
cord-017142-vx3rgs4r	128	7	should	should	MD
cord-017142-vx3rgs4r	128	8	be	be	VB
cord-017142-vx3rgs4r	128	9	considered	consider	VBN
cord-017142-vx3rgs4r	128	10	in	in	IN
cord-017142-vx3rgs4r	128	11	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	128	12	amyloid	amyloid	NN
cord-017142-vx3rgs4r	128	13	patients	patient	NNS
cord-017142-vx3rgs4r	128	14	with	with	IN
cord-017142-vx3rgs4r	128	15	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	128	16	episodes	episode	NNS
cord-017142-vx3rgs4r	128	17	of	of	IN
cord-017142-vx3rgs4r	128	18	non	non	JJ
cord-017142-vx3rgs4r	128	19	-	-	JJ
cord-017142-vx3rgs4r	128	20	sustained	sustained	JJ
cord-017142-vx3rgs4r	128	21	VT	VT	NNP
cord-017142-vx3rgs4r	128	22	,	,	,
cord-017142-vx3rgs4r	128	23	unexplained	unexplained	JJ
cord-017142-vx3rgs4r	128	24	syncope	syncope	NN
cord-017142-vx3rgs4r	128	25	,	,	,
cord-017142-vx3rgs4r	128	26	young	young	JJ
cord-017142-vx3rgs4r	128	27	age	age	NN
cord-017142-vx3rgs4r	128	28	at	at	IN
cord-017142-vx3rgs4r	128	29	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	128	30	,	,	,
cord-017142-vx3rgs4r	128	31	early	early	JJ
cord-017142-vx3rgs4r	128	32	stages	stage	NNS
cord-017142-vx3rgs4r	128	33	of	of	IN
cord-017142-vx3rgs4r	128	34	disease	disease	NN
cord-017142-vx3rgs4r	128	35	at	at	IN
cord-017142-vx3rgs4r	128	36	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	128	37	with	with	IN
cord-017142-vx3rgs4r	128	38	low	low	JJ
cord-017142-vx3rgs4r	128	39	levels	level	NNS
cord-017142-vx3rgs4r	128	40	of	of	IN
cord-017142-vx3rgs4r	128	41	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	128	42	biomarkers	biomarker	NNS
cord-017142-vx3rgs4r	128	43	,	,	,
cord-017142-vx3rgs4r	128	44	and	and	CC
cord-017142-vx3rgs4r	128	45	prognosis	prognosis	NN
cord-017142-vx3rgs4r	129	1	>	>	XX
cord-017142-vx3rgs4r	130	1	1	1	CD
cord-017142-vx3rgs4r	130	2	year	year	NN
cord-017142-vx3rgs4r	130	3	[	[	-LRB-
cord-017142-vx3rgs4r	130	4	47	47	CD
cord-017142-vx3rgs4r	130	5	,	,	,
cord-017142-vx3rgs4r	130	6	48	48	CD
cord-017142-vx3rgs4r	130	7	,	,	,
cord-017142-vx3rgs4r	130	8	71	71	CD
cord-017142-vx3rgs4r	130	9	,	,	,
cord-017142-vx3rgs4r	130	10	127	127	CD
cord-017142-vx3rgs4r	130	11	]	]	-RRB-
cord-017142-vx3rgs4r	130	12	.	.	.
cord-017142-vx3rgs4r	131	1	Anti	anti	JJ
cord-017142-vx3rgs4r	131	2	-	-	JJ
cord-017142-vx3rgs4r	131	3	myeloma	myeloma	JJ
cord-017142-vx3rgs4r	131	4	drug	drug	NN
cord-017142-vx3rgs4r	131	5	-	-	HYPH
cord-017142-vx3rgs4r	131	6	related	relate	VBN
cord-017142-vx3rgs4r	131	7	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	131	8	:	:	:
cord-017142-vx3rgs4r	131	9	Proteasome	Proteasome	NNP
cord-017142-vx3rgs4r	131	10	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	131	11	are	be	VBP
cord-017142-vx3rgs4r	131	12	currently	currently	RB
cord-017142-vx3rgs4r	131	13	the	the	DT
cord-017142-vx3rgs4r	131	14	main	main	JJ
cord-017142-vx3rgs4r	131	15	class	class	NN
cord-017142-vx3rgs4r	131	16	of	of	IN
cord-017142-vx3rgs4r	131	17	drugs	drug	NNS
cord-017142-vx3rgs4r	131	18	used	use	VBN
cord-017142-vx3rgs4r	131	19	in	in	IN
cord-017142-vx3rgs4r	131	20	front	front	JJ
cord-017142-vx3rgs4r	131	21	line	line	NN
cord-017142-vx3rgs4r	131	22	and	and	CC
cord-017142-vx3rgs4r	131	23	in	in	IN
cord-017142-vx3rgs4r	131	24	the	the	DT
cord-017142-vx3rgs4r	131	25	relapsed	relapse	VBN
cord-017142-vx3rgs4r	131	26	setting	setting	NN
cord-017142-vx3rgs4r	131	27	of	of	IN
cord-017142-vx3rgs4r	131	28	MM	MM	NNP
cord-017142-vx3rgs4r	131	29	.	.	.
cord-017142-vx3rgs4r	132	1	FDA	FDA	NNP
cord-017142-vx3rgs4r	132	2	-	-	HYPH
cord-017142-vx3rgs4r	132	3	approved	approve	VBN
cord-017142-vx3rgs4r	132	4	therapies	therapy	NNS
cord-017142-vx3rgs4r	132	5	in	in	IN
cord-017142-vx3rgs4r	132	6	this	this	DT
cord-017142-vx3rgs4r	132	7	class	class	NN
cord-017142-vx3rgs4r	132	8	include	include	VBP
cord-017142-vx3rgs4r	132	9	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	132	10	,	,	,
cord-017142-vx3rgs4r	132	11	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	132	12	,	,	,
cord-017142-vx3rgs4r	132	13	and	and	CC
cord-017142-vx3rgs4r	132	14	ixazomib	ixazomib	NNP
cord-017142-vx3rgs4r	132	15	[	[	-LRB-
cord-017142-vx3rgs4r	132	16	93	93	CD
cord-017142-vx3rgs4r	132	17	]	]	-RRB-
cord-017142-vx3rgs4r	132	18	.	.	.
cord-017142-vx3rgs4r	133	1	Among	among	IN
cord-017142-vx3rgs4r	133	2	them	-PRON-	PRP
cord-017142-vx3rgs4r	133	3	,	,	,
cord-017142-vx3rgs4r	133	4	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	133	5	has	have	VBZ
cord-017142-vx3rgs4r	133	6	shown	show	VBN
cord-017142-vx3rgs4r	133	7	the	the	DT
cord-017142-vx3rgs4r	133	8	highest	high	JJS
cord-017142-vx3rgs4r	133	9	rates	rate	NNS
cord-017142-vx3rgs4r	133	10	of	of	IN
cord-017142-vx3rgs4r	133	11	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	133	12	.	.	.
cord-017142-vx3rgs4r	134	1	In	in	IN
cord-017142-vx3rgs4r	134	2	a	a	DT
cord-017142-vx3rgs4r	134	3	meta	meta	JJ
cord-017142-vx3rgs4r	134	4	-	-	HYPH
cord-017142-vx3rgs4r	134	5	analysis	analysis	NN
cord-017142-vx3rgs4r	134	6	looking	look	VBG
cord-017142-vx3rgs4r	134	7	at	at	IN
cord-017142-vx3rgs4r	134	8	the	the	DT
cord-017142-vx3rgs4r	134	9	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	134	10	of	of	IN
cord-017142-vx3rgs4r	134	11	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	134	12	,	,	,
cord-017142-vx3rgs4r	134	13	all	all	DT
cord-017142-vx3rgs4r	134	14	-	-	HYPH
cord-017142-vx3rgs4r	134	15	grade	grade	NN
cord-017142-vx3rgs4r	134	16	and	and	CC
cord-017142-vx3rgs4r	134	17	high	high	JJ
cord-017142-vx3rgs4r	134	18	-	-	HYPH
cord-017142-vx3rgs4r	134	19	grade	grade	NN
cord-017142-vx3rgs4r	134	20	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	134	21	were	be	VBD
cord-017142-vx3rgs4r	134	22	seen	see	VBN
cord-017142-vx3rgs4r	134	23	in	in	IN
cord-017142-vx3rgs4r	134	24	18	18	CD
cord-017142-vx3rgs4r	134	25	%	%	NN
cord-017142-vx3rgs4r	134	26	and	and	CC
cord-017142-vx3rgs4r	134	27	8	8	CD
cord-017142-vx3rgs4r	134	28	%	%	NN
cord-017142-vx3rgs4r	134	29	of	of	IN
cord-017142-vx3rgs4r	134	30	patients	patient	NNS
cord-017142-vx3rgs4r	134	31	,	,	,
cord-017142-vx3rgs4r	134	32	respectively	respectively	RB
cord-017142-vx3rgs4r	134	33	,	,	,
cord-017142-vx3rgs4r	134	34	higher	high	JJR
cord-017142-vx3rgs4r	134	35	than	than	IN
cord-017142-vx3rgs4r	134	36	the	the	DT
cord-017142-vx3rgs4r	134	37	control	control	NN
cord-017142-vx3rgs4r	134	38	arm	arm	NN
cord-017142-vx3rgs4r	134	39	.	.	.
cord-017142-vx3rgs4r	135	1	The	the	DT
cord-017142-vx3rgs4r	135	2	most	most	RBS
cord-017142-vx3rgs4r	135	3	significant	significant	JJ
cord-017142-vx3rgs4r	135	4	events	event	NNS
cord-017142-vx3rgs4r	135	5	included	include	VBD
cord-017142-vx3rgs4r	135	6	heart	heart	NN
cord-017142-vx3rgs4r	135	7	failure	failure	NN
cord-017142-vx3rgs4r	135	8	(	(	-LRB-
cord-017142-vx3rgs4r	135	9	5	5	CD
cord-017142-vx3rgs4r	135	10	%	%	NN
cord-017142-vx3rgs4r	135	11	)	)	-RRB-
cord-017142-vx3rgs4r	135	12	,	,	,
cord-017142-vx3rgs4r	135	13	arrhythmias	arrhythmia	NNS
cord-017142-vx3rgs4r	135	14	(	(	-LRB-
cord-017142-vx3rgs4r	135	15	2.5	2.5	CD
cord-017142-vx3rgs4r	135	16	%	%	NN
cord-017142-vx3rgs4r	135	17	)	)	-RRB-
cord-017142-vx3rgs4r	135	18	,	,	,
cord-017142-vx3rgs4r	135	19	and	and	CC
cord-017142-vx3rgs4r	135	20	ischemic	ischemic	JJ
cord-017142-vx3rgs4r	135	21	events	event	NNS
cord-017142-vx3rgs4r	135	22	(	(	-LRB-
cord-017142-vx3rgs4r	135	23	2	2	CD
cord-017142-vx3rgs4r	135	24	%	%	NN
cord-017142-vx3rgs4r	135	25	)	)	-RRB-
cord-017142-vx3rgs4r	135	26	.	.	.
cord-017142-vx3rgs4r	136	1	Rare	rare	JJ
cord-017142-vx3rgs4r	136	2	reports	report	NNS
cord-017142-vx3rgs4r	136	3	of	of	IN
cord-017142-vx3rgs4r	136	4	carfilzomibassociated	carfilzomibassociate	VBN
cord-017142-vx3rgs4r	136	5	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	136	6	arrests	arrest	NNS
cord-017142-vx3rgs4r	136	7	also	also	RB
cord-017142-vx3rgs4r	136	8	exist	exist	VBP
cord-017142-vx3rgs4r	136	9	.	.	.
cord-017142-vx3rgs4r	137	1	Risk	risk	NN
cord-017142-vx3rgs4r	137	2	can	can	MD
cord-017142-vx3rgs4r	137	3	be	be	VB
cord-017142-vx3rgs4r	137	4	higher	high	JJR
cord-017142-vx3rgs4r	137	5	in	in	IN
cord-017142-vx3rgs4r	137	6	patients	patient	NNS
cord-017142-vx3rgs4r	137	7	with	with	IN
cord-017142-vx3rgs4r	137	8	comorbidities	comorbiditie	NNS
cord-017142-vx3rgs4r	137	9	such	such	JJ
cord-017142-vx3rgs4r	137	10	as	as	IN
cord-017142-vx3rgs4r	137	11	older	old	JJR
cord-017142-vx3rgs4r	137	12	age	age	NN
cord-017142-vx3rgs4r	137	13	,	,	,
cord-017142-vx3rgs4r	137	14	obesity	obesity	NN
cord-017142-vx3rgs4r	137	15	,	,	,
cord-017142-vx3rgs4r	137	16	anemia	anemia	NN
cord-017142-vx3rgs4r	137	17	,	,	,
cord-017142-vx3rgs4r	137	18	kidney	kidney	NN
cord-017142-vx3rgs4r	137	19	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	137	20	,	,	,
cord-017142-vx3rgs4r	137	21	previous	previous	JJ
cord-017142-vx3rgs4r	137	22	mediastinal	mediastinal	JJ
cord-017142-vx3rgs4r	137	23	radiation	radiation	NN
cord-017142-vx3rgs4r	137	24	,	,	,
cord-017142-vx3rgs4r	137	25	high	high	JJ
cord-017142-vx3rgs4r	137	26	-	-	HYPH
cord-017142-vx3rgs4r	137	27	dose	dose	NN
cord-017142-vx3rgs4r	137	28	corticosteroids	corticosteroid	NNS
cord-017142-vx3rgs4r	137	29	,	,	,
cord-017142-vx3rgs4r	137	30	prior	prior	JJ
cord-017142-vx3rgs4r	137	31	or	or	CC
cord-017142-vx3rgs4r	137	32	concurrent	concurrent	JJ
cord-017142-vx3rgs4r	137	33	anthracycline	anthracycline	JJ
cord-017142-vx3rgs4r	137	34	exposure	exposure	NN
cord-017142-vx3rgs4r	137	35	,	,	,
cord-017142-vx3rgs4r	137	36	use	use	NN
cord-017142-vx3rgs4r	137	37	of	of	IN
cord-017142-vx3rgs4r	137	38	higher	high	JJR
cord-017142-vx3rgs4r	137	39	carfilzomib	carfilzomib	JJ
cord-017142-vx3rgs4r	137	40	doses	dose	NNS
cord-017142-vx3rgs4r	137	41	,	,	,
cord-017142-vx3rgs4r	137	42	short	short	JJ
cord-017142-vx3rgs4r	137	43	infusion	infusion	NN
cord-017142-vx3rgs4r	137	44	times	time	NNS
cord-017142-vx3rgs4r	137	45	,	,	,
cord-017142-vx3rgs4r	137	46	and	and	CC
cord-017142-vx3rgs4r	137	47	undiagnosed	undiagnosed	JJ
cord-017142-vx3rgs4r	137	48	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	137	49	[	[	-LRB-
cord-017142-vx3rgs4r	137	50	5	5	CD
cord-017142-vx3rgs4r	137	51	,	,	,
cord-017142-vx3rgs4r	137	52	52	52	CD
cord-017142-vx3rgs4r	137	53	,	,	,
cord-017142-vx3rgs4r	137	54	92	92	CD
cord-017142-vx3rgs4r	137	55	,	,	,
cord-017142-vx3rgs4r	137	56	133	133	CD
cord-017142-vx3rgs4r	137	57	,	,	,
cord-017142-vx3rgs4r	137	58	135	135	CD
cord-017142-vx3rgs4r	137	59	]	]	-RRB-
cord-017142-vx3rgs4r	137	60	.	.	.
cord-017142-vx3rgs4r	138	1	Anecdotal	anecdotal	JJ
cord-017142-vx3rgs4r	138	2	reports	report	NNS
cord-017142-vx3rgs4r	138	3	suggest	suggest	VBP
cord-017142-vx3rgs4r	138	4	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	138	5	may	may	MD
cord-017142-vx3rgs4r	138	6	lead	lead	VB
cord-017142-vx3rgs4r	138	7	to	to	IN
cord-017142-vx3rgs4r	138	8	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	138	9	as	as	RB
cord-017142-vx3rgs4r	138	10	well	well	RB
cord-017142-vx3rgs4r	138	11	,	,	,
cord-017142-vx3rgs4r	138	12	although	although	IN
cord-017142-vx3rgs4r	138	13	a	a	DT
cord-017142-vx3rgs4r	138	14	recent	recent	JJ
cord-017142-vx3rgs4r	138	15	meta	meta	NNP
cord-017142-vx3rgs4r	138	16	-	-	HYPH
cord-017142-vx3rgs4r	138	17	analysis	analysis	NN
cord-017142-vx3rgs4r	138	18	did	do	VBD
cord-017142-vx3rgs4r	138	19	not	not	RB
cord-017142-vx3rgs4r	138	20	find	find	VB
cord-017142-vx3rgs4r	138	21	a	a	DT
cord-017142-vx3rgs4r	138	22	significantly	significantly	RB
cord-017142-vx3rgs4r	138	23	increased	increase	VBN
cord-017142-vx3rgs4r	138	24	risk	risk	NN
cord-017142-vx3rgs4r	138	25	compared	compare	VBN
cord-017142-vx3rgs4r	138	26	to	to	IN
cord-017142-vx3rgs4r	138	27	the	the	DT
cord-017142-vx3rgs4r	138	28	control	control	NN
cord-017142-vx3rgs4r	138	29	arm	arm	NN
cord-017142-vx3rgs4r	138	30	[	[	-LRB-
cord-017142-vx3rgs4r	138	31	128	128	CD
cord-017142-vx3rgs4r	138	32	,	,	,
cord-017142-vx3rgs4r	138	33	136	136	CD
cord-017142-vx3rgs4r	138	34	]	]	-RRB-
cord-017142-vx3rgs4r	138	35	.	.	.
cord-017142-vx3rgs4r	139	1	The	the	DT
cord-017142-vx3rgs4r	139	2	first	first	JJ
cord-017142-vx3rgs4r	139	3	intervention	intervention	NN
cord-017142-vx3rgs4r	139	4	in	in	IN
cord-017142-vx3rgs4r	139	5	suspected	suspect	VBN
cord-017142-vx3rgs4r	139	6	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	139	7	is	be	VBZ
cord-017142-vx3rgs4r	139	8	to	to	TO
cord-017142-vx3rgs4r	139	9	hold	hold	VB
cord-017142-vx3rgs4r	139	10	further	further	JJ
cord-017142-vx3rgs4r	139	11	therapy	therapy	NN
cord-017142-vx3rgs4r	139	12	and	and	CC
cord-017142-vx3rgs4r	139	13	follow	follow	VB
cord-017142-vx3rgs4r	139	14	expectant	expectant	JJ
cord-017142-vx3rgs4r	139	15	management	management	NN
cord-017142-vx3rgs4r	139	16	.	.	.
cord-017142-vx3rgs4r	140	1	In	in	IN
cord-017142-vx3rgs4r	140	2	cases	case	NNS
cord-017142-vx3rgs4r	140	3	of	of	IN
cord-017142-vx3rgs4r	140	4	congestive	congestive	JJ
cord-017142-vx3rgs4r	140	5	heart	heart	NN
cord-017142-vx3rgs4r	140	6	failure	failure	NN
cord-017142-vx3rgs4r	140	7	,	,	,
cord-017142-vx3rgs4r	140	8	once	once	IN
cord-017142-vx3rgs4r	140	9	the	the	DT
cord-017142-vx3rgs4r	140	10	heart	heart	NN
cord-017142-vx3rgs4r	140	11	failure	failure	NN
cord-017142-vx3rgs4r	140	12	symptoms	symptom	NNS
cord-017142-vx3rgs4r	140	13	improve	improve	VBP
cord-017142-vx3rgs4r	140	14	,	,	,
cord-017142-vx3rgs4r	140	15	it	-PRON-	PRP
cord-017142-vx3rgs4r	140	16	is	be	VBZ
cord-017142-vx3rgs4r	140	17	reasonable	reasonable	JJ
cord-017142-vx3rgs4r	140	18	to	to	TO
cord-017142-vx3rgs4r	140	19	restart	restart	VB
cord-017142-vx3rgs4r	140	20	the	the	DT
cord-017142-vx3rgs4r	140	21	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	140	22	at	at	IN
cord-017142-vx3rgs4r	140	23	a	a	DT
cord-017142-vx3rgs4r	140	24	lower	low	JJR
cord-017142-vx3rgs4r	140	25	dose	dose	NN
cord-017142-vx3rgs4r	140	26	,	,	,
cord-017142-vx3rgs4r	140	27	with	with	IN
cord-017142-vx3rgs4r	140	28	a	a	DT
cord-017142-vx3rgs4r	140	29	longer	long	JJR
cord-017142-vx3rgs4r	140	30	infusion	infusion	NN
cord-017142-vx3rgs4r	140	31	time	time	NN
cord-017142-vx3rgs4r	140	32	and	and	CC
cord-017142-vx3rgs4r	140	33	limiting	limit	VBG
cord-017142-vx3rgs4r	140	34	peri	peri	NN
cord-017142-vx3rgs4r	140	35	-	-	HYPH
cord-017142-vx3rgs4r	140	36	treatment	treatment	NN
cord-017142-vx3rgs4r	140	37	IV	IV	NNP
cord-017142-vx3rgs4r	140	38	fluids	fluid	NNS
cord-017142-vx3rgs4r	140	39	.	.	.
cord-017142-vx3rgs4r	141	1	Arrhythmic	arrhythmic	JJ
cord-017142-vx3rgs4r	141	2	events	event	NNS
cord-017142-vx3rgs4r	141	3	would	would	MD
cord-017142-vx3rgs4r	141	4	require	require	VB
cord-017142-vx3rgs4r	141	5	careful	careful	JJ
cord-017142-vx3rgs4r	141	6	consideration	consideration	NN
cord-017142-vx3rgs4r	141	7	regarding	regard	VBG
cord-017142-vx3rgs4r	141	8	rechallenging	rechallenge	VBG
cord-017142-vx3rgs4r	141	9	patients	patient	NNS
cord-017142-vx3rgs4r	141	10	after	after	IN
cord-017142-vx3rgs4r	141	11	considering	consider	VBG
cord-017142-vx3rgs4r	141	12	the	the	DT
cord-017142-vx3rgs4r	141	13	risk	risk	NN
cord-017142-vx3rgs4r	141	14	-	-	HYPH
cord-017142-vx3rgs4r	141	15	benefit	benefit	NN
cord-017142-vx3rgs4r	141	16	ratio	ratio	NN
cord-017142-vx3rgs4r	141	17	.	.	.
cord-017142-vx3rgs4r	142	1	Hyperviscosity	Hyperviscosity	NNP
cord-017142-vx3rgs4r	142	2	syndrome	syndrome	NN
cord-017142-vx3rgs4r	142	3	:	:	:
cord-017142-vx3rgs4r	142	4	In	in	IN
cord-017142-vx3rgs4r	142	5	a	a	DT
cord-017142-vx3rgs4r	142	6	patient	patient	NN
cord-017142-vx3rgs4r	142	7	undergoing	undergo	VBG
cord-017142-vx3rgs4r	142	8	work	work	NN
cord-017142-vx3rgs4r	142	9	-	-	HYPH
cord-017142-vx3rgs4r	142	10	up	up	NN
cord-017142-vx3rgs4r	142	11	for	for	IN
cord-017142-vx3rgs4r	142	12	MM	MM	NNP
cord-017142-vx3rgs4r	142	13	or	or	CC
cord-017142-vx3rgs4r	142	14	with	with	IN
cord-017142-vx3rgs4r	142	15	an	an	DT
cord-017142-vx3rgs4r	142	16	established	establish	VBN
cord-017142-vx3rgs4r	142	17	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	142	18	,	,	,
cord-017142-vx3rgs4r	142	19	symptoms	symptom	NNS
cord-017142-vx3rgs4r	142	20	of	of	IN
cord-017142-vx3rgs4r	142	21	headache	headache	NN
cord-017142-vx3rgs4r	142	22	,	,	,
cord-017142-vx3rgs4r	142	23	nose	nose	NN
cord-017142-vx3rgs4r	142	24	bleeds	bleed	VBZ
cord-017142-vx3rgs4r	142	25	,	,	,
cord-017142-vx3rgs4r	142	26	mental	mental	JJ
cord-017142-vx3rgs4r	142	27	status	status	NN
cord-017142-vx3rgs4r	142	28	or	or	CC
cord-017142-vx3rgs4r	142	29	visual	visual	JJ
cord-017142-vx3rgs4r	142	30	changes	change	NNS
cord-017142-vx3rgs4r	142	31	,	,	,
cord-017142-vx3rgs4r	142	32	auditory	auditory	JJ
cord-017142-vx3rgs4r	142	33	symptoms	symptom	NNS
cord-017142-vx3rgs4r	142	34	,	,	,
cord-017142-vx3rgs4r	142	35	focal	focal	JJ
cord-017142-vx3rgs4r	142	36	weakness	weakness	NN
cord-017142-vx3rgs4r	142	37	,	,	,
cord-017142-vx3rgs4r	142	38	excessive	excessive	JJ
cord-017142-vx3rgs4r	142	39	lethargy	lethargy	NN
cord-017142-vx3rgs4r	142	40	,	,	,
cord-017142-vx3rgs4r	142	41	seizures	seizure	NNS
cord-017142-vx3rgs4r	142	42	,	,	,
cord-017142-vx3rgs4r	142	43	or	or	CC
cord-017142-vx3rgs4r	142	44	coma	coma	NN
cord-017142-vx3rgs4r	142	45	should	should	MD
cord-017142-vx3rgs4r	142	46	raise	raise	VB
cord-017142-vx3rgs4r	142	47	suspicion	suspicion	NN
cord-017142-vx3rgs4r	142	48	for	for	IN
cord-017142-vx3rgs4r	142	49	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	142	50	syndrome	syndrome	NN
cord-017142-vx3rgs4r	142	51	.	.	.
cord-017142-vx3rgs4r	143	1	Though	though	IN
cord-017142-vx3rgs4r	143	2	extremely	extremely	RB
cord-017142-vx3rgs4r	143	3	uncommon	uncommon	JJ
cord-017142-vx3rgs4r	143	4	in	in	IN
cord-017142-vx3rgs4r	143	5	MM	MM	NNP
cord-017142-vx3rgs4r	143	6	(	(	-LRB-
cord-017142-vx3rgs4r	143	7	5	5	CD
cord-017142-vx3rgs4r	143	8	%	%	NN
cord-017142-vx3rgs4r	143	9	)	)	-RRB-
cord-017142-vx3rgs4r	143	10	in	in	IN
cord-017142-vx3rgs4r	143	11	comparison	comparison	NN
cord-017142-vx3rgs4r	143	12	to	to	IN
cord-017142-vx3rgs4r	143	13	Waldenström	Waldenström	NNP
cord-017142-vx3rgs4r	143	14	's	's	POS
cord-017142-vx3rgs4r	143	15	macroglobulinemia	macroglobulinemia	NN
cord-017142-vx3rgs4r	143	16	(	(	-LRB-
cord-017142-vx3rgs4r	143	17	10	10	CD
cord-017142-vx3rgs4r	143	18	-	-	SYM
cord-017142-vx3rgs4r	143	19	30	30	CD
cord-017142-vx3rgs4r	143	20	%	%	NN
cord-017142-vx3rgs4r	143	21	)	)	-RRB-
cord-017142-vx3rgs4r	143	22	,	,	,
cord-017142-vx3rgs4r	143	23	a	a	DT
cord-017142-vx3rgs4r	143	24	low	low	JJ
cord-017142-vx3rgs4r	143	25	threshold	threshold	NN
cord-017142-vx3rgs4r	143	26	should	should	MD
cord-017142-vx3rgs4r	143	27	be	be	VB
cord-017142-vx3rgs4r	143	28	kept	keep	VBN
cord-017142-vx3rgs4r	143	29	to	to	TO
cord-017142-vx3rgs4r	143	30	work	work	VB
cord-017142-vx3rgs4r	143	31	up	up	RP
cord-017142-vx3rgs4r	143	32	a	a	DT
cord-017142-vx3rgs4r	143	33	patient	patient	NN
cord-017142-vx3rgs4r	143	34	for	for	IN
cord-017142-vx3rgs4r	143	35	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	143	36	as	as	IN
cord-017142-vx3rgs4r	143	37	this	this	DT
cord-017142-vx3rgs4r	143	38	can	can	MD
cord-017142-vx3rgs4r	143	39	be	be	VB
cord-017142-vx3rgs4r	143	40	fatal	fatal	JJ
cord-017142-vx3rgs4r	143	41	if	if	IN
cord-017142-vx3rgs4r	143	42	not	not	RB
cord-017142-vx3rgs4r	143	43	recognized	recognize	VBN
cord-017142-vx3rgs4r	143	44	early	early	RB
cord-017142-vx3rgs4r	143	45	.	.	.
cord-017142-vx3rgs4r	144	1	The	the	DT
cord-017142-vx3rgs4r	144	2	viscosity	viscosity	NN
cord-017142-vx3rgs4r	144	3	tends	tend	VBZ
cord-017142-vx3rgs4r	144	4	to	to	TO
cord-017142-vx3rgs4r	144	5	increase	increase	VB
cord-017142-vx3rgs4r	144	6	with	with	IN
cord-017142-vx3rgs4r	144	7	increase	increase	NN
cord-017142-vx3rgs4r	144	8	in	in	IN
cord-017142-vx3rgs4r	144	9	molecular	molecular	JJ
cord-017142-vx3rgs4r	144	10	size	size	NN
cord-017142-vx3rgs4r	144	11	,	,	,
cord-017142-vx3rgs4r	144	12	shape	shape	NN
cord-017142-vx3rgs4r	144	13	,	,	,
cord-017142-vx3rgs4r	144	14	and	and	CC
cord-017142-vx3rgs4r	144	15	weight	weight	NN
cord-017142-vx3rgs4r	144	16	of	of	IN
cord-017142-vx3rgs4r	144	17	the	the	DT
cord-017142-vx3rgs4r	144	18	involved	involve	VBN
cord-017142-vx3rgs4r	144	19	paraprotein	paraprotein	NNP
cord-017142-vx3rgs4r	144	20	and	and	CC
cord-017142-vx3rgs4r	144	21	abnormal	abnormal	JJ
cord-017142-vx3rgs4r	144	22	polymerization	polymerization	NN
cord-017142-vx3rgs4r	144	23	.	.	.
cord-017142-vx3rgs4r	145	1	Patients	patient	NNS
cord-017142-vx3rgs4r	145	2	tend	tend	VBP
cord-017142-vx3rgs4r	145	3	to	to	TO
cord-017142-vx3rgs4r	145	4	develop	develop	VB
cord-017142-vx3rgs4r	145	5	symptoms	symptom	NNS
cord-017142-vx3rgs4r	145	6	when	when	WRB
cord-017142-vx3rgs4r	145	7	the	the	DT
cord-017142-vx3rgs4r	145	8	serum	serum	NN
cord-017142-vx3rgs4r	145	9	viscosity	viscosity	NN
cord-017142-vx3rgs4r	145	10	reaches	reach	VBZ
cord-017142-vx3rgs4r	145	11	4	4	CD
cord-017142-vx3rgs4r	145	12	centi	centi	NNP
cord-017142-vx3rgs4r	145	13	-	-	HYPH
cord-017142-vx3rgs4r	145	14	Poise	Poise	NNP
cord-017142-vx3rgs4r	145	15	(	(	-LRB-
cord-017142-vx3rgs4r	145	16	cp	cp	NN
cord-017142-vx3rgs4r	145	17	)	)	-RRB-
cord-017142-vx3rgs4r	145	18	(	(	-LRB-
cord-017142-vx3rgs4r	145	19	normal	normal	JJ
cord-017142-vx3rgs4r	145	20	serum	serum	NN
cord-017142-vx3rgs4r	145	21	viscosity	viscosity	NN
cord-017142-vx3rgs4r	145	22	,	,	,
cord-017142-vx3rgs4r	145	23	1.4	1.4	CD
cord-017142-vx3rgs4r	145	24	-	-	SYM
cord-017142-vx3rgs4r	145	25	1.8	1.8	CD
cord-017142-vx3rgs4r	145	26	cp	cp	NN
cord-017142-vx3rgs4r	145	27	)	)	-RRB-
cord-017142-vx3rgs4r	145	28	.	.	.
cord-017142-vx3rgs4r	146	1	This	this	DT
cord-017142-vx3rgs4r	146	2	usually	usually	RB
cord-017142-vx3rgs4r	146	3	corresponds	correspond	VBZ
cord-017142-vx3rgs4r	146	4	to	to	IN
cord-017142-vx3rgs4r	146	5	an	an	DT
cord-017142-vx3rgs4r	146	6	M	M	NNP
cord-017142-vx3rgs4r	146	7	spike	spike	NN
cord-017142-vx3rgs4r	146	8	of	of	IN
cord-017142-vx3rgs4r	146	9	3	3	CD
cord-017142-vx3rgs4r	146	10	g	g	NN
cord-017142-vx3rgs4r	146	11	/	/	SYM
cord-017142-vx3rgs4r	146	12	dL	dl	NN
cord-017142-vx3rgs4r	146	13	if	if	IN
cord-017142-vx3rgs4r	146	14	IgM	IgM	NNP
cord-017142-vx3rgs4r	146	15	,	,	,
cord-017142-vx3rgs4r	146	16	4	4	CD
cord-017142-vx3rgs4r	146	17	g	g	NN
cord-017142-vx3rgs4r	146	18	/	/	SYM
cord-017142-vx3rgs4r	146	19	dL	dL	NNP
cord-017142-vx3rgs4r	146	20	for	for	IN
cord-017142-vx3rgs4r	146	21	IgG	IgG	NNP
cord-017142-vx3rgs4r	146	22	,	,	,
cord-017142-vx3rgs4r	146	23	and	and	CC
cord-017142-vx3rgs4r	146	24	6	6	CD
cord-017142-vx3rgs4r	146	25	-	-	SYM
cord-017142-vx3rgs4r	146	26	7	7	CD
cord-017142-vx3rgs4r	146	27	g	g	NN
cord-017142-vx3rgs4r	146	28	/	/	SYM
cord-017142-vx3rgs4r	146	29	dL	dL	NNP
cord-017142-vx3rgs4r	146	30	for	for	IN
cord-017142-vx3rgs4r	146	31	IgA	IgA	NNP
cord-017142-vx3rgs4r	146	32	paraproteinemia	paraproteinemia	NNP
cord-017142-vx3rgs4r	146	33	.	.	.
cord-017142-vx3rgs4r	147	1	However	however	RB
cord-017142-vx3rgs4r	147	2	,	,	,
cord-017142-vx3rgs4r	147	3	these	these	DT
cord-017142-vx3rgs4r	147	4	levels	level	NNS
cord-017142-vx3rgs4r	147	5	are	be	VBP
cord-017142-vx3rgs4r	147	6	arbitrary	arbitrary	JJ
cord-017142-vx3rgs4r	147	7	,	,	,
cord-017142-vx3rgs4r	147	8	and	and	CC
cord-017142-vx3rgs4r	147	9	the	the	DT
cord-017142-vx3rgs4r	147	10	relationship	relationship	NN
cord-017142-vx3rgs4r	147	11	is	be	VBZ
cord-017142-vx3rgs4r	147	12	nonlinear	nonlinear	JJ
cord-017142-vx3rgs4r	147	13	as	as	IN
cord-017142-vx3rgs4r	147	14	patients	patient	NNS
cord-017142-vx3rgs4r	147	15	can	can	MD
cord-017142-vx3rgs4r	147	16	have	have	VB
cord-017142-vx3rgs4r	147	17	symptoms	symptom	NNS
cord-017142-vx3rgs4r	147	18	even	even	RB
cord-017142-vx3rgs4r	147	19	with	with	IN
cord-017142-vx3rgs4r	147	20	a	a	DT
cord-017142-vx3rgs4r	147	21	level	level	NN
cord-017142-vx3rgs4r	147	22	lower	lower	RBR
cord-017142-vx3rgs4r	147	23	or	or	CC
cord-017142-vx3rgs4r	147	24	could	could	MD
cord-017142-vx3rgs4r	147	25	be	be	VB
cord-017142-vx3rgs4r	147	26	asymptomatic	asymptomatic	JJ
cord-017142-vx3rgs4r	147	27	with	with	IN
cord-017142-vx3rgs4r	147	28	a	a	DT
cord-017142-vx3rgs4r	147	29	higher	high	JJR
cord-017142-vx3rgs4r	147	30	level	level	NN
cord-017142-vx3rgs4r	147	31	[	[	-LRB-
cord-017142-vx3rgs4r	147	32	49	49	CD
cord-017142-vx3rgs4r	147	33	,	,	,
cord-017142-vx3rgs4r	147	34	94	94	CD
cord-017142-vx3rgs4r	147	35	]	]	-RRB-
cord-017142-vx3rgs4r	147	36	.	.	.
cord-017142-vx3rgs4r	148	1	In	in	IN
cord-017142-vx3rgs4r	148	2	MM	MM	NNP
cord-017142-vx3rgs4r	148	3	,	,	,
cord-017142-vx3rgs4r	148	4	IgG	IgG	NNP
cord-017142-vx3rgs4r	148	5	(	(	-LRB-
cord-017142-vx3rgs4r	148	6	mostly	mostly	RB
cord-017142-vx3rgs4r	148	7	IgG3	IgG3	NNP
cord-017142-vx3rgs4r	148	8	)	)	-RRB-
cord-017142-vx3rgs4r	148	9	or	or	CC
cord-017142-vx3rgs4r	148	10	IgA	IgA	NNP
cord-017142-vx3rgs4r	148	11	paraprotein	paraprotein	NNP
cord-017142-vx3rgs4r	148	12	tends	tend	VBZ
cord-017142-vx3rgs4r	148	13	to	to	TO
cord-017142-vx3rgs4r	148	14	be	be	VB
cord-017142-vx3rgs4r	148	15	reported	report	VBN
cord-017142-vx3rgs4r	148	16	more	more	RBR
cord-017142-vx3rgs4r	148	17	commonly	commonly	RB
cord-017142-vx3rgs4r	148	18	with	with	IN
cord-017142-vx3rgs4r	148	19	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	148	20	than	than	IN
cord-017142-vx3rgs4r	148	21	IgM	IgM	NNP
cord-017142-vx3rgs4r	148	22	most	most	RBS
cord-017142-vx3rgs4r	148	23	likely	likely	JJ
cord-017142-vx3rgs4r	148	24	due	due	IN
cord-017142-vx3rgs4r	148	25	to	to	IN
cord-017142-vx3rgs4r	148	26	the	the	DT
cord-017142-vx3rgs4r	148	27	inherent	inherent	JJ
cord-017142-vx3rgs4r	148	28	rarity	rarity	NN
cord-017142-vx3rgs4r	148	29	of	of	IN
cord-017142-vx3rgs4r	148	30	IgM	IgM	NNP
cord-017142-vx3rgs4r	148	31	MM	MM	NNP
cord-017142-vx3rgs4r	148	32	[	[	-LRB-
cord-017142-vx3rgs4r	148	33	28	28	CD
cord-017142-vx3rgs4r	148	34	,	,	,
cord-017142-vx3rgs4r	148	35	81	81	CD
cord-017142-vx3rgs4r	148	36	]	]	-RRB-
cord-017142-vx3rgs4r	148	37	.	.	.
cord-017142-vx3rgs4r	149	1	Due	due	IN
cord-017142-vx3rgs4r	149	2	to	to	IN
cord-017142-vx3rgs4r	149	3	increased	increase	VBN
cord-017142-vx3rgs4r	149	4	serum	serum	NN
cord-017142-vx3rgs4r	149	5	viscosity	viscosity	NN
cord-017142-vx3rgs4r	149	6	,	,	,
cord-017142-vx3rgs4r	149	7	there	there	EX
cord-017142-vx3rgs4r	149	8	is	be	VBZ
cord-017142-vx3rgs4r	149	9	impaired	impair	VBN
cord-017142-vx3rgs4r	149	10	blood	blood	NN
cord-017142-vx3rgs4r	149	11	flow	flow	NN
cord-017142-vx3rgs4r	149	12	and	and	CC
cord-017142-vx3rgs4r	149	13	sludging	sludging	NN
cord-017142-vx3rgs4r	149	14	throughout	throughout	IN
cord-017142-vx3rgs4r	149	15	the	the	DT
cord-017142-vx3rgs4r	149	16	microvasculature	microvasculature	NN
cord-017142-vx3rgs4r	149	17	,	,	,
cord-017142-vx3rgs4r	149	18	leading	lead	VBG
cord-017142-vx3rgs4r	149	19	to	to	IN
cord-017142-vx3rgs4r	149	20	tissue	tissue	NN
cord-017142-vx3rgs4r	149	21	ischemia	ischemia	NN
cord-017142-vx3rgs4r	149	22	,	,	,
cord-017142-vx3rgs4r	149	23	placing	place	VBG
cord-017142-vx3rgs4r	149	24	the	the	DT
cord-017142-vx3rgs4r	149	25	patient	patient	NN
cord-017142-vx3rgs4r	149	26	at	at	IN
cord-017142-vx3rgs4r	149	27	risk	risk	NN
cord-017142-vx3rgs4r	149	28	for	for	IN
cord-017142-vx3rgs4r	149	29	thrombosis	thrombosis	NN
cord-017142-vx3rgs4r	149	30	to	to	IN
cord-017142-vx3rgs4r	149	31	major	major	JJ
cord-017142-vx3rgs4r	149	32	organs	organ	NNS
cord-017142-vx3rgs4r	149	33	leading	lead	VBG
cord-017142-vx3rgs4r	149	34	to	to	IN
cord-017142-vx3rgs4r	149	35	myocardial	myocardial	JJ
cord-017142-vx3rgs4r	149	36	,	,	,
cord-017142-vx3rgs4r	149	37	cerebrovascular	cerebrovascular	JJ
cord-017142-vx3rgs4r	149	38	,	,	,
cord-017142-vx3rgs4r	149	39	and	and	CC
cord-017142-vx3rgs4r	149	40	retinal	retinal	JJ
cord-017142-vx3rgs4r	149	41	ischemia	ischemia	NN
cord-017142-vx3rgs4r	149	42	.	.	.
cord-017142-vx3rgs4r	150	1	With	with	IN
cord-017142-vx3rgs4r	150	2	passive	passive	JJ
cord-017142-vx3rgs4r	150	3	venous	venous	JJ
cord-017142-vx3rgs4r	150	4	congestion	congestion	NN
cord-017142-vx3rgs4r	150	5	,	,	,
cord-017142-vx3rgs4r	150	6	patients	patient	NNS
cord-017142-vx3rgs4r	150	7	can	can	MD
cord-017142-vx3rgs4r	150	8	often	often	RB
cord-017142-vx3rgs4r	150	9	present	present	VB
cord-017142-vx3rgs4r	150	10	with	with	IN
cord-017142-vx3rgs4r	150	11	bleeding	bleed	VBG
cord-017142-vx3rgs4r	150	12	symptoms	symptom	NNS
cord-017142-vx3rgs4r	150	13	.	.	.
cord-017142-vx3rgs4r	151	1	Thorough	thorough	JJ
cord-017142-vx3rgs4r	151	2	physical	physical	JJ
cord-017142-vx3rgs4r	151	3	exam	exam	NN
cord-017142-vx3rgs4r	151	4	is	be	VBZ
cord-017142-vx3rgs4r	151	5	paramount	paramount	NN
cord-017142-vx3rgs4r	151	6	including	include	VBG
cord-017142-vx3rgs4r	151	7	a	a	DT
cord-017142-vx3rgs4r	151	8	fundoscopic	fundoscopic	NNP
cord-017142-vx3rgs4r	151	9	exam	exam	NN
cord-017142-vx3rgs4r	151	10	,	,	,
cord-017142-vx3rgs4r	151	11	which	which	WDT
cord-017142-vx3rgs4r	151	12	may	may	MD
cord-017142-vx3rgs4r	151	13	reveal	reveal	VB
cord-017142-vx3rgs4r	151	14	dilated	dilated	JJ
cord-017142-vx3rgs4r	151	15	,	,	,
cord-017142-vx3rgs4r	151	16	tortuous	tortuous	JJ
cord-017142-vx3rgs4r	151	17	,	,	,
cord-017142-vx3rgs4r	151	18	engorged	engorged	JJ
cord-017142-vx3rgs4r	151	19	,	,	,
cord-017142-vx3rgs4r	151	20	"	"	``
cord-017142-vx3rgs4r	151	21	sausage	sausage	NN
cord-017142-vx3rgs4r	151	22	"	"	''
cord-017142-vx3rgs4r	151	23	veins	vein	NNS
cord-017142-vx3rgs4r	151	24	with	with	IN
cord-017142-vx3rgs4r	151	25	associated	associated	JJ
cord-017142-vx3rgs4r	151	26	hemorrhages	hemorrhage	NNS
cord-017142-vx3rgs4r	151	27	.	.	.
cord-017142-vx3rgs4r	152	1	Bleeding	bleed	VBG
cord-017142-vx3rgs4r	152	2	at	at	IN
cord-017142-vx3rgs4r	152	3	sites	site	NNS
cord-017142-vx3rgs4r	152	4	involving	involve	VBG
cord-017142-vx3rgs4r	152	5	mucosa	mucosa	JJ
cord-017142-vx3rgs4r	152	6	is	be	VBZ
cord-017142-vx3rgs4r	152	7	common	common	JJ
cord-017142-vx3rgs4r	152	8	which	which	WDT
cord-017142-vx3rgs4r	152	9	can	can	MD
cord-017142-vx3rgs4r	152	10	include	include	VB
cord-017142-vx3rgs4r	152	11	oral	oral	JJ
cord-017142-vx3rgs4r	152	12	and	and	CC
cord-017142-vx3rgs4r	152	13	nasal	nasal	JJ
cord-017142-vx3rgs4r	152	14	cavity	cavity	NN
cord-017142-vx3rgs4r	152	15	,	,	,
cord-017142-vx3rgs4r	152	16	the	the	DT
cord-017142-vx3rgs4r	152	17	uterus	uterus	NN
cord-017142-vx3rgs4r	152	18	,	,	,
cord-017142-vx3rgs4r	152	19	and	and	CC
cord-017142-vx3rgs4r	152	20	the	the	DT
cord-017142-vx3rgs4r	152	21	gastrointestinal	gastrointestinal	JJ
cord-017142-vx3rgs4r	152	22	tract	tract	NN
cord-017142-vx3rgs4r	152	23	.	.	.
cord-017142-vx3rgs4r	153	1	Purpura	purpura	NN
cord-017142-vx3rgs4r	153	2	and	and	CC
cord-017142-vx3rgs4r	153	3	skin	skin	NN
cord-017142-vx3rgs4r	153	4	bruising	bruising	NN
cord-017142-vx3rgs4r	153	5	are	be	VBP
cord-017142-vx3rgs4r	153	6	also	also	RB
cord-017142-vx3rgs4r	153	7	common	common	JJ
cord-017142-vx3rgs4r	153	8	.	.	.
cord-017142-vx3rgs4r	154	1	Consensus	Consensus	NNP
cord-017142-vx3rgs4r	154	2	MM	MM	NNP
cord-017142-vx3rgs4r	154	3	guidelines	guideline	NNS
cord-017142-vx3rgs4r	154	4	do	do	VBP
cord-017142-vx3rgs4r	154	5	not	not	RB
cord-017142-vx3rgs4r	154	6	recommend	recommend	VB
cord-017142-vx3rgs4r	154	7	plasmapheresis	plasmapheresis	NN
cord-017142-vx3rgs4r	154	8	in	in	IN
cord-017142-vx3rgs4r	154	9	the	the	DT
cord-017142-vx3rgs4r	154	10	absence	absence	NN
cord-017142-vx3rgs4r	154	11	of	of	IN
cord-017142-vx3rgs4r	154	12	signs	sign	NNS
cord-017142-vx3rgs4r	154	13	or	or	CC
cord-017142-vx3rgs4r	154	14	symptoms	symptom	NNS
cord-017142-vx3rgs4r	154	15	for	for	IN
cord-017142-vx3rgs4r	154	16	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	154	17	.	.	.
cord-017142-vx3rgs4r	155	1	However	however	RB
cord-017142-vx3rgs4r	155	2	,	,	,
cord-017142-vx3rgs4r	155	3	a	a	DT
cord-017142-vx3rgs4r	155	4	low	low	JJ
cord-017142-vx3rgs4r	155	5	threshold	threshold	NN
cord-017142-vx3rgs4r	155	6	should	should	MD
cord-017142-vx3rgs4r	155	7	be	be	VB
cord-017142-vx3rgs4r	155	8	maintained	maintain	VBN
cord-017142-vx3rgs4r	155	9	to	to	TO
cord-017142-vx3rgs4r	155	10	initiate	initiate	VB
cord-017142-vx3rgs4r	155	11	treatment	treatment	NN
cord-017142-vx3rgs4r	155	12	at	at	IN
cord-017142-vx3rgs4r	155	13	the	the	DT
cord-017142-vx3rgs4r	155	14	earliest	early	JJS
cord-017142-vx3rgs4r	155	15	suspicion	suspicion	NN
cord-017142-vx3rgs4r	155	16	of	of	IN
cord-017142-vx3rgs4r	155	17	symptoms	symptom	NNS
cord-017142-vx3rgs4r	155	18	or	or	CC
cord-017142-vx3rgs4r	155	19	signs	sign	NNS
cord-017142-vx3rgs4r	155	20	;	;	:
cord-017142-vx3rgs4r	155	21	it	-PRON-	PRP
cord-017142-vx3rgs4r	155	22	follows	follow	VBZ
cord-017142-vx3rgs4r	155	23	a	a	DT
cord-017142-vx3rgs4r	155	24	two	two	CD
cord-017142-vx3rgs4r	155	25	-	-	HYPH
cord-017142-vx3rgs4r	155	26	prong	prong	NN
cord-017142-vx3rgs4r	155	27	strategy	strategy	NN
cord-017142-vx3rgs4r	155	28	consisting	consist	VBG
cord-017142-vx3rgs4r	155	29	of	of	IN
cord-017142-vx3rgs4r	155	30	immediate	immediate	JJ
cord-017142-vx3rgs4r	155	31	plasmapheresis	plasmapheresis	NN
cord-017142-vx3rgs4r	155	32	to	to	TO
cord-017142-vx3rgs4r	155	33	lower	lower	VB
cord-017142-vx3rgs4r	155	34	the	the	DT
cord-017142-vx3rgs4r	155	35	excess	excess	JJ
cord-017142-vx3rgs4r	155	36	paraproteins	paraprotein	NNS
cord-017142-vx3rgs4r	155	37	and	and	CC
cord-017142-vx3rgs4r	155	38	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	155	39	directed	direct	VBN
cord-017142-vx3rgs4r	155	40	at	at	IN
cord-017142-vx3rgs4r	155	41	the	the	DT
cord-017142-vx3rgs4r	155	42	primary	primary	JJ
cord-017142-vx3rgs4r	155	43	process	process	NN
cord-017142-vx3rgs4r	155	44	of	of	IN
cord-017142-vx3rgs4r	155	45	MM	MM	NNP
cord-017142-vx3rgs4r	155	46	.	.	.
cord-017142-vx3rgs4r	156	1	Unlike	unlike	IN
cord-017142-vx3rgs4r	156	2	the	the	DT
cord-017142-vx3rgs4r	156	3	response	response	NN
cord-017142-vx3rgs4r	156	4	of	of	IN
cord-017142-vx3rgs4r	156	5	IgM	IgM	NNP
cord-017142-vx3rgs4r	156	6	-	-	HYPH
cord-017142-vx3rgs4r	156	7	related	relate	VBN
cord-017142-vx3rgs4r	156	8	paraproteinemia	paraproteinemia	NN
cord-017142-vx3rgs4r	156	9	(	(	-LRB-
cord-017142-vx3rgs4r	156	10	>	>	NFP
cord-017142-vx3rgs4r	156	11	80	80	CD
cord-017142-vx3rgs4r	156	12	%	%	NN
cord-017142-vx3rgs4r	156	13	intravascular	intravascular	JJ
cord-017142-vx3rgs4r	156	14	)	)	-RRB-
cord-017142-vx3rgs4r	156	15	,	,	,
cord-017142-vx3rgs4r	156	16	where	where	WRB
cord-017142-vx3rgs4r	156	17	a	a	DT
cord-017142-vx3rgs4r	156	18	50	50	CD
cord-017142-vx3rgs4r	156	19	-	-	SYM
cord-017142-vx3rgs4r	156	20	60	60	CD
cord-017142-vx3rgs4r	156	21	%	%	NN
cord-017142-vx3rgs4r	156	22	reduction	reduction	NN
cord-017142-vx3rgs4r	156	23	of	of	IN
cord-017142-vx3rgs4r	156	24	viscosity	viscosity	NN
cord-017142-vx3rgs4r	156	25	is	be	VBZ
cord-017142-vx3rgs4r	156	26	expected	expect	VBN
cord-017142-vx3rgs4r	156	27	with	with	IN
cord-017142-vx3rgs4r	156	28	one	one	CD
cord-017142-vx3rgs4r	156	29	treatment	treatment	NN
cord-017142-vx3rgs4r	156	30	,	,	,
cord-017142-vx3rgs4r	156	31	IgA	IgA	NNP
cord-017142-vx3rgs4r	156	32	or	or	CC
cord-017142-vx3rgs4r	156	33	IgG	IgG	NNP
cord-017142-vx3rgs4r	156	34	(	(	-LRB-
cord-017142-vx3rgs4r	156	35	<	<	XX
cord-017142-vx3rgs4r	156	36	50	50	CD
cord-017142-vx3rgs4r	156	37	%	%	NN
cord-017142-vx3rgs4r	156	38	intravascular	intravascular	JJ
cord-017142-vx3rgs4r	156	39	)	)	-RRB-
cord-017142-vx3rgs4r	157	1	hyperviscosity	hyperviscosity	NNP
cord-017142-vx3rgs4r	157	2	can	can	MD
cord-017142-vx3rgs4r	157	3	take	take	VB
cord-017142-vx3rgs4r	157	4	several	several	JJ
cord-017142-vx3rgs4r	157	5	sessions	session	NNS
cord-017142-vx3rgs4r	157	6	to	to	TO
cord-017142-vx3rgs4r	157	7	achieve	achieve	VB
cord-017142-vx3rgs4r	157	8	the	the	DT
cord-017142-vx3rgs4r	157	9	same	same	JJ
cord-017142-vx3rgs4r	157	10	result	result	NN
cord-017142-vx3rgs4r	157	11	[	[	-LRB-
cord-017142-vx3rgs4r	157	12	83	83	CD
cord-017142-vx3rgs4r	157	13	]	]	-RRB-
cord-017142-vx3rgs4r	157	14	.	.	.
cord-017142-vx3rgs4r	158	1	If	if	IN
cord-017142-vx3rgs4r	158	2	plasmapheresis	plasmapheresis	NN
cord-017142-vx3rgs4r	158	3	is	be	VBZ
cord-017142-vx3rgs4r	158	4	not	not	RB
cord-017142-vx3rgs4r	158	5	readily	readily	RB
cord-017142-vx3rgs4r	158	6	available	available	JJ
cord-017142-vx3rgs4r	158	7	and	and	CC
cord-017142-vx3rgs4r	158	8	the	the	DT
cord-017142-vx3rgs4r	158	9	patient	patient	NN
cord-017142-vx3rgs4r	158	10	is	be	VBZ
cord-017142-vx3rgs4r	158	11	having	have	VBG
cord-017142-vx3rgs4r	158	12	lifethreatening	lifethreatene	VBG
cord-017142-vx3rgs4r	158	13	symptoms	symptom	NNS
cord-017142-vx3rgs4r	158	14	,	,	,
cord-017142-vx3rgs4r	158	15	phlebotomy	phlebotomy	NN
cord-017142-vx3rgs4r	158	16	may	may	MD
cord-017142-vx3rgs4r	158	17	reduce	reduce	VB
cord-017142-vx3rgs4r	158	18	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	158	19	-	-	HYPH
cord-017142-vx3rgs4r	158	20	related	relate	VBN
cord-017142-vx3rgs4r	158	21	acute	acute	JJ
cord-017142-vx3rgs4r	158	22	symptoms	symptom	NNS
cord-017142-vx3rgs4r	158	23	.	.	.
cord-017142-vx3rgs4r	159	1	In	in	IN
cord-017142-vx3rgs4r	159	2	MM	MM	NNP
cord-017142-vx3rgs4r	159	3	patients	patient	NNS
cord-017142-vx3rgs4r	159	4	,	,	,
cord-017142-vx3rgs4r	159	5	who	who	WP
cord-017142-vx3rgs4r	159	6	are	be	VBP
cord-017142-vx3rgs4r	159	7	often	often	RB
cord-017142-vx3rgs4r	159	8	anemic	anemic	JJ
cord-017142-vx3rgs4r	159	9	at	at	IN
cord-017142-vx3rgs4r	159	10	presentation	presentation	NN
cord-017142-vx3rgs4r	159	11	,	,	,
cord-017142-vx3rgs4r	159	12	blood	blood	NN
cord-017142-vx3rgs4r	159	13	transfusions	transfusion	NNS
cord-017142-vx3rgs4r	159	14	should	should	MD
cord-017142-vx3rgs4r	159	15	be	be	VB
cord-017142-vx3rgs4r	159	16	done	do	VBN
cord-017142-vx3rgs4r	159	17	only	only	RB
cord-017142-vx3rgs4r	159	18	in	in	IN
cord-017142-vx3rgs4r	159	19	emergent	emergent	JJ
cord-017142-vx3rgs4r	159	20	situations	situation	NNS
cord-017142-vx3rgs4r	159	21	and	and	CC
cord-017142-vx3rgs4r	159	22	with	with	IN
cord-017142-vx3rgs4r	159	23	caution	caution	NN
cord-017142-vx3rgs4r	159	24	until	until	IN
cord-017142-vx3rgs4r	159	25	after	after	IN
cord-017142-vx3rgs4r	159	26	the	the	DT
cord-017142-vx3rgs4r	159	27	initiation	initiation	NN
cord-017142-vx3rgs4r	159	28	of	of	IN
cord-017142-vx3rgs4r	159	29	plasmapheresis	plasmapheresis	NN
cord-017142-vx3rgs4r	159	30	to	to	TO
cord-017142-vx3rgs4r	159	31	prevent	prevent	VB
cord-017142-vx3rgs4r	159	32	rise	rise	NN
cord-017142-vx3rgs4r	159	33	in	in	IN
cord-017142-vx3rgs4r	159	34	serum	serum	NN
cord-017142-vx3rgs4r	159	35	viscosity	viscosity	NN
cord-017142-vx3rgs4r	159	36	[	[	-LRB-
cord-017142-vx3rgs4r	159	37	110	110	CD
cord-017142-vx3rgs4r	159	38	,	,	,
cord-017142-vx3rgs4r	159	39	119	119	CD
cord-017142-vx3rgs4r	159	40	]	]	-RRB-
cord-017142-vx3rgs4r	159	41	.	.	.
cord-017142-vx3rgs4r	160	1	Venous	venous	JJ
cord-017142-vx3rgs4r	160	2	thromboembolism	thromboembolism	NN
cord-017142-vx3rgs4r	160	3	:	:	:
cord-017142-vx3rgs4r	161	1	Patients	patient	NNS
cord-017142-vx3rgs4r	161	2	with	with	IN
cord-017142-vx3rgs4r	161	3	MM	MM	NNP
cord-017142-vx3rgs4r	161	4	are	be	VBP
cord-017142-vx3rgs4r	161	5	at	at	IN
cord-017142-vx3rgs4r	161	6	an	an	DT
cord-017142-vx3rgs4r	161	7	increased	increase	VBN
cord-017142-vx3rgs4r	161	8	risk	risk	NN
cord-017142-vx3rgs4r	161	9	of	of	IN
cord-017142-vx3rgs4r	161	10	venous	venous	JJ
cord-017142-vx3rgs4r	161	11	thrombosis	thrombosis	NN
cord-017142-vx3rgs4r	161	12	due	due	IN
cord-017142-vx3rgs4r	161	13	to	to	IN
cord-017142-vx3rgs4r	161	14	patient	patient	NN
cord-017142-vx3rgs4r	161	15	-	-	HYPH
cord-017142-vx3rgs4r	161	16	related	relate	VBN
cord-017142-vx3rgs4r	161	17	,	,	,
cord-017142-vx3rgs4r	161	18	disease	disease	NN
cord-017142-vx3rgs4r	161	19	-	-	HYPH
cord-017142-vx3rgs4r	161	20	related	relate	VBN
cord-017142-vx3rgs4r	161	21	,	,	,
cord-017142-vx3rgs4r	161	22	and	and	CC
cord-017142-vx3rgs4r	161	23	treatment	treatment	NN
cord-017142-vx3rgs4r	161	24	-	-	HYPH
cord-017142-vx3rgs4r	161	25	related	relate	VBN
cord-017142-vx3rgs4r	161	26	factors	factor	NNS
cord-017142-vx3rgs4r	161	27	.	.	.
cord-017142-vx3rgs4r	162	1	Patient	patient	NN
cord-017142-vx3rgs4r	162	2	-	-	HYPH
cord-017142-vx3rgs4r	162	3	related	relate	VBN
cord-017142-vx3rgs4r	162	4	factors	factor	NNS
cord-017142-vx3rgs4r	162	5	include	include	VBP
cord-017142-vx3rgs4r	162	6	older	old	JJR
cord-017142-vx3rgs4r	162	7	age	age	NN
cord-017142-vx3rgs4r	162	8	,	,	,
cord-017142-vx3rgs4r	162	9	recent	recent	JJ
cord-017142-vx3rgs4r	162	10	surgery	surgery	NN
cord-017142-vx3rgs4r	162	11	or	or	CC
cord-017142-vx3rgs4r	162	12	immobilization	immobilization	NN
cord-017142-vx3rgs4r	162	13	,	,	,
cord-017142-vx3rgs4r	162	14	and	and	CC
cord-017142-vx3rgs4r	162	15	decreased	decrease	VBD
cord-017142-vx3rgs4r	162	16	functional	functional	JJ
cord-017142-vx3rgs4r	162	17	status	status	NN
cord-017142-vx3rgs4r	162	18	;	;	:
cord-017142-vx3rgs4r	162	19	the	the	DT
cord-017142-vx3rgs4r	162	20	major	major	JJ
cord-017142-vx3rgs4r	162	21	disease	disease	NN
cord-017142-vx3rgs4r	162	22	-	-	HYPH
cord-017142-vx3rgs4r	162	23	related	relate	VBN
cord-017142-vx3rgs4r	162	24	factor	factor	NN
cord-017142-vx3rgs4r	162	25	is	be	VBZ
cord-017142-vx3rgs4r	162	26	increased	increase	VBN
cord-017142-vx3rgs4r	162	27	pro	pro	JJ
cord-017142-vx3rgs4r	162	28	-	-	JJ
cord-017142-vx3rgs4r	162	29	thrombotic	thrombotic	JJ
cord-017142-vx3rgs4r	162	30	status	status	NN
cord-017142-vx3rgs4r	162	31	from	from	IN
cord-017142-vx3rgs4r	162	32	heightened	heighten	VBN
cord-017142-vx3rgs4r	162	33	inflammatory	inflammatory	JJ
cord-017142-vx3rgs4r	162	34	markers	marker	NNS
cord-017142-vx3rgs4r	162	35	,	,	,
cord-017142-vx3rgs4r	162	36	especially	especially	RB
cord-017142-vx3rgs4r	162	37	at	at	IN
cord-017142-vx3rgs4r	162	38	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	162	39	.	.	.
cord-017142-vx3rgs4r	163	1	There	there	EX
cord-017142-vx3rgs4r	163	2	is	be	VBZ
cord-017142-vx3rgs4r	163	3	a	a	DT
cord-017142-vx3rgs4r	163	4	high	high	JJ
cord-017142-vx3rgs4r	163	5	level	level	NN
cord-017142-vx3rgs4r	163	6	of	of	IN
cord-017142-vx3rgs4r	163	7	factor	factor	NN
cord-017142-vx3rgs4r	163	8	VIII	VIII	NNP
cord-017142-vx3rgs4r	163	9	and	and	CC
cord-017142-vx3rgs4r	163	10	von	von	NNP
cord-017142-vx3rgs4r	163	11	Willebrand	Willebrand	NNP
cord-017142-vx3rgs4r	163	12	factor	factor	NN
cord-017142-vx3rgs4r	163	13	as	as	RB
cord-017142-vx3rgs4r	163	14	well	well	RB
cord-017142-vx3rgs4r	163	15	as	as	IN
cord-017142-vx3rgs4r	163	16	acquired	acquire	VBN
cord-017142-vx3rgs4r	163	17	resistance	resistance	NN
cord-017142-vx3rgs4r	163	18	to	to	IN
cord-017142-vx3rgs4r	163	19	activated	activate	VBN
cord-017142-vx3rgs4r	163	20	protein	protein	NN
cord-017142-vx3rgs4r	163	21	C	C	NNP
cord-017142-vx3rgs4r	163	22	[	[	-LRB-
cord-017142-vx3rgs4r	163	23	33	33	CD
cord-017142-vx3rgs4r	163	24	]	]	-RRB-
cord-017142-vx3rgs4r	163	25	.	.	.
cord-017142-vx3rgs4r	164	1	In	in	IN
cord-017142-vx3rgs4r	164	2	addition	addition	NN
cord-017142-vx3rgs4r	164	3	,	,	,
cord-017142-vx3rgs4r	164	4	MM	MM	NNP
cord-017142-vx3rgs4r	164	5	patients	patient	NNS
cord-017142-vx3rgs4r	164	6	treated	treat	VBN
cord-017142-vx3rgs4r	164	7	with	with	IN
cord-017142-vx3rgs4r	164	8	immunomodulators	immunomodulator	NNS
cord-017142-vx3rgs4r	164	9	especially	especially	RB
cord-017142-vx3rgs4r	164	10	thalidomide	thalidomide	JJ
cord-017142-vx3rgs4r	164	11	or	or	CC
cord-017142-vx3rgs4r	164	12	lenalidomide	lenalidomide	NN
cord-017142-vx3rgs4r	164	13	used	use	VBN
cord-017142-vx3rgs4r	164	14	in	in	IN
cord-017142-vx3rgs4r	164	15	combination	combination	NN
cord-017142-vx3rgs4r	164	16	with	with	IN
cord-017142-vx3rgs4r	164	17	steroids	steroid	NNS
cord-017142-vx3rgs4r	164	18	or	or	CC
cord-017142-vx3rgs4r	164	19	other	other	JJ
cord-017142-vx3rgs4r	164	20	chemotherapeutic	chemotherapeutic	JJ
cord-017142-vx3rgs4r	164	21	agents	agent	NNS
cord-017142-vx3rgs4r	164	22	increase	increase	VBP
cord-017142-vx3rgs4r	164	23	the	the	DT
cord-017142-vx3rgs4r	164	24	risk	risk	NN
cord-017142-vx3rgs4r	164	25	further	further	RB
cord-017142-vx3rgs4r	164	26	[	[	-LRB-
cord-017142-vx3rgs4r	164	27	89	89	CD
cord-017142-vx3rgs4r	164	28	,	,	,
cord-017142-vx3rgs4r	164	29	132	132	CD
cord-017142-vx3rgs4r	164	30	]	]	-RRB-
cord-017142-vx3rgs4r	164	31	.	.	.
cord-017142-vx3rgs4r	165	1	Management	management	NN
cord-017142-vx3rgs4r	165	2	of	of	IN
cord-017142-vx3rgs4r	165	3	acute	acute	JJ
cord-017142-vx3rgs4r	165	4	DVT	DVT	NNP
cord-017142-vx3rgs4r	165	5	or	or	CC
cord-017142-vx3rgs4r	165	6	PE	PE	NNP
cord-017142-vx3rgs4r	165	7	involves	involve	VBZ
cord-017142-vx3rgs4r	165	8	withholding	withhold	VBG
cord-017142-vx3rgs4r	165	9	the	the	DT
cord-017142-vx3rgs4r	165	10	offending	offending	JJ
cord-017142-vx3rgs4r	165	11	drug	drug	NN
cord-017142-vx3rgs4r	165	12	if	if	IN
cord-017142-vx3rgs4r	165	13	any	any	DT
cord-017142-vx3rgs4r	165	14	and	and	CC
cord-017142-vx3rgs4r	165	15	starting	start	VBG
cord-017142-vx3rgs4r	165	16	immediate	immediate	JJ
cord-017142-vx3rgs4r	165	17	systemic	systemic	JJ
cord-017142-vx3rgs4r	165	18	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	165	19	with	with	IN
cord-017142-vx3rgs4r	165	20	low	low	JJ
cord-017142-vx3rgs4r	165	21	-	-	HYPH
cord-017142-vx3rgs4r	165	22	molecular	molecular	JJ
cord-017142-vx3rgs4r	165	23	-	-	HYPH
cord-017142-vx3rgs4r	165	24	weight	weight	NN
cord-017142-vx3rgs4r	165	25	heparin	heparin	NN
cord-017142-vx3rgs4r	165	26	or	or	CC
cord-017142-vx3rgs4r	165	27	unfractionated	unfractionate	VBN
cord-017142-vx3rgs4r	165	28	heparin	heparin	NN
cord-017142-vx3rgs4r	165	29	.	.	.
cord-017142-vx3rgs4r	166	1	LMWH	LMWH	NNP
cord-017142-vx3rgs4r	166	2	is	be	VBZ
cord-017142-vx3rgs4r	166	3	the	the	DT
cord-017142-vx3rgs4r	166	4	preferred	preferred	JJ
cord-017142-vx3rgs4r	166	5	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	166	6	at	at	IN
cord-017142-vx3rgs4r	166	7	the	the	DT
cord-017142-vx3rgs4r	166	8	time	time	NN
cord-017142-vx3rgs4r	166	9	of	of	IN
cord-017142-vx3rgs4r	166	10	transition	transition	NN
cord-017142-vx3rgs4r	166	11	to	to	IN
cord-017142-vx3rgs4r	166	12	outpatient	outpatient	NN
cord-017142-vx3rgs4r	166	13	therapy	therapy	NN
cord-017142-vx3rgs4r	166	14	as	as	IN
cord-017142-vx3rgs4r	166	15	evidence	evidence	NN
cord-017142-vx3rgs4r	166	16	suggests	suggest	VBZ
cord-017142-vx3rgs4r	166	17	better	well	JJR
cord-017142-vx3rgs4r	166	18	safety	safety	NN
cord-017142-vx3rgs4r	166	19	and	and	CC
cord-017142-vx3rgs4r	166	20	a	a	DT
cord-017142-vx3rgs4r	166	21	superior	superior	JJ
cord-017142-vx3rgs4r	166	22	efficacy	efficacy	NN
cord-017142-vx3rgs4r	166	23	in	in	IN
cord-017142-vx3rgs4r	166	24	stabilizing	stabilize	VBG
cord-017142-vx3rgs4r	166	25	the	the	DT
cord-017142-vx3rgs4r	166	26	clot	clot	NN
cord-017142-vx3rgs4r	166	27	in	in	IN
cord-017142-vx3rgs4r	166	28	comparison	comparison	NN
cord-017142-vx3rgs4r	166	29	to	to	IN
cord-017142-vx3rgs4r	166	30	other	other	JJ
cord-017142-vx3rgs4r	166	31	anticoagulants	anticoagulant	NNS
cord-017142-vx3rgs4r	166	32	[	[	-LRB-
cord-017142-vx3rgs4r	166	33	67	67	CD
cord-017142-vx3rgs4r	166	34	]	]	-RRB-
cord-017142-vx3rgs4r	166	35	.	.	.
cord-017142-vx3rgs4r	167	1	Factors	factor	NNS
cord-017142-vx3rgs4r	167	2	that	that	WDT
cord-017142-vx3rgs4r	167	3	make	make	VBP
cord-017142-vx3rgs4r	167	4	oral	oral	JJ
cord-017142-vx3rgs4r	167	5	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	167	6	less	less	RBR
cord-017142-vx3rgs4r	167	7	ideal	ideal	NN
cord-017142-vx3rgs4r	167	8	is	be	VBZ
cord-017142-vx3rgs4r	167	9	drugdrug	drugdrug	JJ
cord-017142-vx3rgs4r	167	10	interaction	interaction	NN
cord-017142-vx3rgs4r	167	11	and	and	CC
cord-017142-vx3rgs4r	167	12	unreliable	unreliable	JJ
cord-017142-vx3rgs4r	167	13	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	167	14	levels	level	NNS
cord-017142-vx3rgs4r	167	15	resulting	result	VBG
cord-017142-vx3rgs4r	167	16	from	from	IN
cord-017142-vx3rgs4r	167	17	patient	patient	NN
cord-017142-vx3rgs4r	167	18	-	-	HYPH
cord-017142-vx3rgs4r	167	19	related	relate	VBN
cord-017142-vx3rgs4r	167	20	malnutrition	malnutrition	NN
cord-017142-vx3rgs4r	167	21	,	,	,
cord-017142-vx3rgs4r	167	22	infection	infection	NN
cord-017142-vx3rgs4r	167	23	,	,	,
cord-017142-vx3rgs4r	167	24	and	and	CC
cord-017142-vx3rgs4r	167	25	drug	drug	NN
cord-017142-vx3rgs4r	167	26	holds	hold	VBZ
cord-017142-vx3rgs4r	167	27	from	from	IN
cord-017142-vx3rgs4r	167	28	cytopenias	cytopenias	NNP
cord-017142-vx3rgs4r	167	29	.	.	.
cord-017142-vx3rgs4r	168	1	Once	once	IN
cord-017142-vx3rgs4r	168	2	full	full	JJ
cord-017142-vx3rgs4r	168	3	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	168	4	is	be	VBZ
cord-017142-vx3rgs4r	168	5	attained	attain	VBN
cord-017142-vx3rgs4r	168	6	,	,	,
cord-017142-vx3rgs4r	168	7	the	the	DT
cord-017142-vx3rgs4r	168	8	immunomodulator	immunomodulator	NN
cord-017142-vx3rgs4r	168	9	can	can	MD
cord-017142-vx3rgs4r	168	10	be	be	VB
cord-017142-vx3rgs4r	168	11	reintroduced	reintroduce	VBN
cord-017142-vx3rgs4r	168	12	.	.	.
cord-017142-vx3rgs4r	169	1	In	in	IN
cord-017142-vx3rgs4r	169	2	the	the	DT
cord-017142-vx3rgs4r	169	3	presence	presence	NN
cord-017142-vx3rgs4r	169	4	of	of	IN
cord-017142-vx3rgs4r	169	5	thrombocytopenia	thrombocytopenia	NN
cord-017142-vx3rgs4r	169	6	,	,	,
cord-017142-vx3rgs4r	169	7	which	which	WDT
cord-017142-vx3rgs4r	169	8	is	be	VBZ
cord-017142-vx3rgs4r	169	9	commonly	commonly	RB
cord-017142-vx3rgs4r	169	10	encountered	encounter	VBN
cord-017142-vx3rgs4r	169	11	in	in	IN
cord-017142-vx3rgs4r	169	12	MM	MM	NNP
cord-017142-vx3rgs4r	169	13	patients	patient	NNS
cord-017142-vx3rgs4r	169	14	,	,	,
cord-017142-vx3rgs4r	169	15	the	the	DT
cord-017142-vx3rgs4r	169	16	dose	dose	NN
cord-017142-vx3rgs4r	169	17	of	of	IN
cord-017142-vx3rgs4r	169	18	LMWH	LMWH	NNP
cord-017142-vx3rgs4r	169	19	needs	need	VBZ
cord-017142-vx3rgs4r	169	20	adjustment	adjustment	NN
cord-017142-vx3rgs4r	169	21	and	and	CC
cord-017142-vx3rgs4r	169	22	in	in	IN
cord-017142-vx3rgs4r	169	23	general	general	JJ
cord-017142-vx3rgs4r	169	24	a	a	DT
cord-017142-vx3rgs4r	169	25	recommendation	recommendation	NN
cord-017142-vx3rgs4r	169	26	of	of	IN
cord-017142-vx3rgs4r	169	27	50	50	CD
cord-017142-vx3rgs4r	169	28	%	%	NN
cord-017142-vx3rgs4r	169	29	dose	dose	NN
cord-017142-vx3rgs4r	169	30	reduction	reduction	NN
cord-017142-vx3rgs4r	169	31	if	if	IN
cord-017142-vx3rgs4r	169	32	platelet	platelet	NN
cord-017142-vx3rgs4r	169	33	counts	count	VBZ
cord-017142-vx3rgs4r	169	34	below	below	IN
cord-017142-vx3rgs4r	169	35	50,000	50,000	CD
cord-017142-vx3rgs4r	169	36	/	/	SYM
cord-017142-vx3rgs4r	169	37	μL	μl	NN
cord-017142-vx3rgs4r	169	38	,	,	,
cord-017142-vx3rgs4r	169	39	and	and	CC
cord-017142-vx3rgs4r	169	40	discontinuation	discontinuation	NN
cord-017142-vx3rgs4r	169	41	if	if	IN
cord-017142-vx3rgs4r	169	42	platelet	platelet	NN
cord-017142-vx3rgs4r	169	43	count	count	VBP
cord-017142-vx3rgs4r	169	44	<	<	XX
cord-017142-vx3rgs4r	169	45	20,000	20,000	CD
cord-017142-vx3rgs4r	170	1	/μL	/μL	:
cord-017142-vx3rgs4r	170	2	is	be	VBZ
cord-017142-vx3rgs4r	170	3	followed	follow	VBN
cord-017142-vx3rgs4r	170	4	.	.	.
cord-017142-vx3rgs4r	171	1	Duration	duration	NN
cord-017142-vx3rgs4r	171	2	of	of	IN
cord-017142-vx3rgs4r	171	3	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	171	4	should	should	MD
cord-017142-vx3rgs4r	171	5	be	be	VB
cord-017142-vx3rgs4r	171	6	a	a	DT
cord-017142-vx3rgs4r	171	7	minimum	minimum	NN
cord-017142-vx3rgs4r	171	8	of	of	IN
cord-017142-vx3rgs4r	171	9	6	6	CD
cord-017142-vx3rgs4r	171	10	months	month	NNS
cord-017142-vx3rgs4r	171	11	;	;	:
cord-017142-vx3rgs4r	171	12	however	however	RB
cord-017142-vx3rgs4r	171	13	in	in	IN
cord-017142-vx3rgs4r	171	14	the	the	DT
cord-017142-vx3rgs4r	171	15	presence	presence	NN
cord-017142-vx3rgs4r	171	16	of	of	IN
cord-017142-vx3rgs4r	171	17	the	the	DT
cord-017142-vx3rgs4r	171	18	offending	offending	JJ
cord-017142-vx3rgs4r	171	19	drug	drug	NN
cord-017142-vx3rgs4r	171	20	,	,	,
cord-017142-vx3rgs4r	171	21	systemic	systemic	JJ
cord-017142-vx3rgs4r	171	22	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	171	23	should	should	MD
cord-017142-vx3rgs4r	171	24	be	be	VB
cord-017142-vx3rgs4r	171	25	continued	continue	VBN
cord-017142-vx3rgs4r	171	26	for	for	IN
cord-017142-vx3rgs4r	171	27	the	the	DT
cord-017142-vx3rgs4r	171	28	total	total	JJ
cord-017142-vx3rgs4r	171	29	duration	duration	NN
cord-017142-vx3rgs4r	171	30	of	of	IN
cord-017142-vx3rgs4r	171	31	therapy	therapy	NN
cord-017142-vx3rgs4r	171	32	[	[	-LRB-
cord-017142-vx3rgs4r	171	33	13	13	CD
cord-017142-vx3rgs4r	171	34	]	]	-RRB-
cord-017142-vx3rgs4r	171	35	.	.	.
cord-017142-vx3rgs4r	172	1	Arterial	arterial	JJ
cord-017142-vx3rgs4r	172	2	thromboembolic	thromboembolic	JJ
cord-017142-vx3rgs4r	172	3	events	event	NNS
cord-017142-vx3rgs4r	172	4	,	,	,
cord-017142-vx3rgs4r	172	5	though	though	IN
cord-017142-vx3rgs4r	172	6	rare	rare	JJ
cord-017142-vx3rgs4r	172	7	,	,	,
cord-017142-vx3rgs4r	172	8	have	have	VBP
cord-017142-vx3rgs4r	172	9	also	also	RB
cord-017142-vx3rgs4r	172	10	been	be	VBN
cord-017142-vx3rgs4r	172	11	reported	report	VBN
cord-017142-vx3rgs4r	172	12	with	with	IN
cord-017142-vx3rgs4r	172	13	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	172	14	,	,	,
cord-017142-vx3rgs4r	172	15	lenalidomide	lenalidomide	NN
cord-017142-vx3rgs4r	172	16	,	,	,
cord-017142-vx3rgs4r	172	17	and	and	CC
cord-017142-vx3rgs4r	172	18	pomalidomide	pomalidomide	NN
cord-017142-vx3rgs4r	172	19	;	;	:
cord-017142-vx3rgs4r	172	20	rarely	rarely	RB
cord-017142-vx3rgs4r	172	21	,	,	,
cord-017142-vx3rgs4r	172	22	this	this	DT
cord-017142-vx3rgs4r	172	23	may	may	MD
cord-017142-vx3rgs4r	172	24	present	present	VB
cord-017142-vx3rgs4r	172	25	as	as	IN
cord-017142-vx3rgs4r	172	26	myocardial	myocardial	JJ
cord-017142-vx3rgs4r	172	27	infarction	infarction	NN
cord-017142-vx3rgs4r	172	28	or	or	CC
cord-017142-vx3rgs4r	172	29	stroke	stroke	NN
cord-017142-vx3rgs4r	172	30	.	.	.
cord-017142-vx3rgs4r	173	1	The	the	DT
cord-017142-vx3rgs4r	173	2	role	role	NN
cord-017142-vx3rgs4r	173	3	of	of	IN
cord-017142-vx3rgs4r	173	4	newer	new	JJR
cord-017142-vx3rgs4r	173	5	oral	oral	JJ
cord-017142-vx3rgs4r	173	6	anticoagulants	anticoagulant	NNS
cord-017142-vx3rgs4r	173	7	including	include	VBG
cord-017142-vx3rgs4r	173	8	factor	factor	NN
cord-017142-vx3rgs4r	173	9	Xa	Xa	NNP
cord-017142-vx3rgs4r	173	10	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	173	11	and	and	CC
cord-017142-vx3rgs4r	173	12	direct	direct	JJ
cord-017142-vx3rgs4r	173	13	thrombin	thrombin	NN
cord-017142-vx3rgs4r	173	14	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	173	15	is	be	VBZ
cord-017142-vx3rgs4r	173	16	currently	currently	RB
cord-017142-vx3rgs4r	173	17	investigational	investigational	JJ
cord-017142-vx3rgs4r	173	18	in	in	IN
cord-017142-vx3rgs4r	173	19	the	the	DT
cord-017142-vx3rgs4r	173	20	treatment	treatment	NN
cord-017142-vx3rgs4r	173	21	of	of	IN
cord-017142-vx3rgs4r	173	22	malignancy	malignancy	NN
cord-017142-vx3rgs4r	173	23	-	-	HYPH
cord-017142-vx3rgs4r	173	24	associated	associate	VBN
cord-017142-vx3rgs4r	173	25	thromboembolic	thromboembolic	JJ
cord-017142-vx3rgs4r	173	26	events	event	NNS
cord-017142-vx3rgs4r	173	27	;	;	:
cord-017142-vx3rgs4r	173	28	however	however	RB
cord-017142-vx3rgs4r	173	29	,	,	,
cord-017142-vx3rgs4r	173	30	they	-PRON-	PRP
cord-017142-vx3rgs4r	173	31	are	be	VBP
cord-017142-vx3rgs4r	173	32	a	a	DT
cord-017142-vx3rgs4r	173	33	good	good	JJ
cord-017142-vx3rgs4r	173	34	alternative	alternative	NN
cord-017142-vx3rgs4r	173	35	for	for	IN
cord-017142-vx3rgs4r	173	36	patients	patient	NNS
cord-017142-vx3rgs4r	173	37	with	with	IN
cord-017142-vx3rgs4r	173	38	renal	renal	JJ
cord-017142-vx3rgs4r	173	39	failure	failure	NN
cord-017142-vx3rgs4r	173	40	[	[	-LRB-
cord-017142-vx3rgs4r	173	41	26	26	CD
cord-017142-vx3rgs4r	173	42	]	]	-RRB-
cord-017142-vx3rgs4r	173	43	.	.	.
cord-017142-vx3rgs4r	174	1	Sepsis	sepsis	NN
cord-017142-vx3rgs4r	174	2	/	/	SYM
cord-017142-vx3rgs4r	174	3	invasive	invasive	JJ
cord-017142-vx3rgs4r	174	4	infections	infection	NNS
cord-017142-vx3rgs4r	174	5	:	:	:
cord-017142-vx3rgs4r	175	1	10	10	CD
cord-017142-vx3rgs4r	175	2	-	-	SYM
cord-017142-vx3rgs4r	175	3	15	15	CD
cord-017142-vx3rgs4r	175	4	%	%	NN
cord-017142-vx3rgs4r	175	5	of	of	IN
cord-017142-vx3rgs4r	175	6	newly	newly	RB
cord-017142-vx3rgs4r	175	7	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	175	8	MM	MM	NNP
cord-017142-vx3rgs4r	175	9	patients	patient	NNS
cord-017142-vx3rgs4r	175	10	succumb	succumb	VBP
cord-017142-vx3rgs4r	175	11	to	to	IN
cord-017142-vx3rgs4r	175	12	the	the	DT
cord-017142-vx3rgs4r	175	13	disease	disease	NN
cord-017142-vx3rgs4r	175	14	in	in	IN
cord-017142-vx3rgs4r	175	15	the	the	DT
cord-017142-vx3rgs4r	175	16	first	first	JJ
cord-017142-vx3rgs4r	175	17	few	few	JJ
cord-017142-vx3rgs4r	175	18	months	month	NNS
cord-017142-vx3rgs4r	175	19	with	with	IN
cord-017142-vx3rgs4r	175	20	infection	infection	NN
cord-017142-vx3rgs4r	175	21	contributing	contribute	VBG
cord-017142-vx3rgs4r	175	22	to	to	IN
cord-017142-vx3rgs4r	175	23	more	more	JJR
cord-017142-vx3rgs4r	175	24	than	than	IN
cord-017142-vx3rgs4r	175	25	half	half	PDT
cord-017142-vx3rgs4r	175	26	the	the	DT
cord-017142-vx3rgs4r	175	27	cases	case	NNS
cord-017142-vx3rgs4r	175	28	[	[	-LRB-
cord-017142-vx3rgs4r	175	29	6	6	CD
cord-017142-vx3rgs4r	175	30	,	,	,
cord-017142-vx3rgs4r	175	31	53	53	CD
cord-017142-vx3rgs4r	175	32	,	,	,
cord-017142-vx3rgs4r	175	33	88	88	CD
cord-017142-vx3rgs4r	175	34	]	]	-RRB-
cord-017142-vx3rgs4r	175	35	.	.	.
cord-017142-vx3rgs4r	176	1	High	high	JJ
cord-017142-vx3rgs4r	176	2	incidence	incidence	NN
cord-017142-vx3rgs4r	176	3	of	of	IN
cord-017142-vx3rgs4r	176	4	early	early	JJ
cord-017142-vx3rgs4r	176	5	infection	infection	NN
cord-017142-vx3rgs4r	176	6	in	in	IN
cord-017142-vx3rgs4r	176	7	MM	MM	NNP
cord-017142-vx3rgs4r	176	8	is	be	VBZ
cord-017142-vx3rgs4r	176	9	due	due	JJ
cord-017142-vx3rgs4r	176	10	to	to	IN
cord-017142-vx3rgs4r	176	11	the	the	DT
cord-017142-vx3rgs4r	176	12	suppressed	suppress	VBN
cord-017142-vx3rgs4r	176	13	humoral	humoral	JJ
cord-017142-vx3rgs4r	176	14	and	and	CC
cord-017142-vx3rgs4r	176	15	T	T	NNP
cord-017142-vx3rgs4r	176	16	cell	cell	NN
cord-017142-vx3rgs4r	176	17	-	-	HYPH
cord-017142-vx3rgs4r	176	18	mediated	mediate	VBN
cord-017142-vx3rgs4r	176	19	immunity	immunity	NN
cord-017142-vx3rgs4r	176	20	by	by	IN
cord-017142-vx3rgs4r	176	21	the	the	DT
cord-017142-vx3rgs4r	176	22	disease	disease	NN
cord-017142-vx3rgs4r	176	23	itself	-PRON-	PRP
cord-017142-vx3rgs4r	176	24	.	.	.
cord-017142-vx3rgs4r	177	1	Immunosuppression	Immunosuppression	NNP
cord-017142-vx3rgs4r	177	2	is	be	VBZ
cord-017142-vx3rgs4r	177	3	mediated	mediate	VBN
cord-017142-vx3rgs4r	177	4	by	by	IN
cord-017142-vx3rgs4r	177	5	disease	disease	NN
cord-017142-vx3rgs4r	177	6	-	-	HYPH
cord-017142-vx3rgs4r	177	7	and	and	CC
cord-017142-vx3rgs4r	177	8	treatment	treatment	NN
cord-017142-vx3rgs4r	177	9	-	-	HYPH
cord-017142-vx3rgs4r	177	10	related	relate	VBN
cord-017142-vx3rgs4r	177	11	factors	factor	NNS
cord-017142-vx3rgs4r	177	12	including	include	VBG
cord-017142-vx3rgs4r	177	13	decreased	decrease	VBD
cord-017142-vx3rgs4r	177	14	ratio	ratio	NN
cord-017142-vx3rgs4r	177	15	of	of	IN
cord-017142-vx3rgs4r	177	16	functional	functional	JJ
cord-017142-vx3rgs4r	177	17	to	to	IN
cord-017142-vx3rgs4r	177	18	dysfunctional	dysfunctional	JJ
cord-017142-vx3rgs4r	177	19	immunoglobulins	immunoglobulin	NNS
cord-017142-vx3rgs4r	177	20	,	,	,
cord-017142-vx3rgs4r	177	21	defects	defect	NNS
cord-017142-vx3rgs4r	177	22	in	in	IN
cord-017142-vx3rgs4r	177	23	antibody	antibody	NN
cord-017142-vx3rgs4r	177	24	opsonization	opsonization	NN
cord-017142-vx3rgs4r	177	25	,	,	,
cord-017142-vx3rgs4r	177	26	steroid	steroid	NN
cord-017142-vx3rgs4r	177	27	-	-	HYPH
cord-017142-vx3rgs4r	177	28	related	relate	VBN
cord-017142-vx3rgs4r	177	29	T	t	NN
cord-017142-vx3rgs4r	177	30	cell	cell	NN
cord-017142-vx3rgs4r	177	31	defects	defect	NNS
cord-017142-vx3rgs4r	177	32	,	,	,
cord-017142-vx3rgs4r	177	33	secondary	secondary	JJ
cord-017142-vx3rgs4r	177	34	immunodeficiency	immunodeficiency	NN
cord-017142-vx3rgs4r	177	35	related	relate	VBN
cord-017142-vx3rgs4r	177	36	to	to	IN
cord-017142-vx3rgs4r	177	37	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	177	38	,	,	,
cord-017142-vx3rgs4r	177	39	restricted	restricted	JJ
cord-017142-vx3rgs4r	177	40	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	177	41	reserve	reserve	NN
cord-017142-vx3rgs4r	177	42	from	from	IN
cord-017142-vx3rgs4r	177	43	thoracic	thoracic	JJ
cord-017142-vx3rgs4r	177	44	rib	rib	NN
cord-017142-vx3rgs4r	177	45	fractures	fracture	NNS
cord-017142-vx3rgs4r	177	46	and	and	CC
cord-017142-vx3rgs4r	177	47	opiate	opiate	NN
cord-017142-vx3rgs4r	177	48	use	use	NN
cord-017142-vx3rgs4r	177	49	,	,	,
cord-017142-vx3rgs4r	177	50	mucosal	mucosal	JJ
cord-017142-vx3rgs4r	177	51	damage	damage	NN
cord-017142-vx3rgs4r	177	52	,	,	,
cord-017142-vx3rgs4r	177	53	indwelling	indwell	VBG
cord-017142-vx3rgs4r	177	54	catheters	catheter	NNS
cord-017142-vx3rgs4r	177	55	,	,	,
cord-017142-vx3rgs4r	177	56	and	and	CC
cord-017142-vx3rgs4r	177	57	presence	presence	NN
cord-017142-vx3rgs4r	177	58	of	of	IN
cord-017142-vx3rgs4r	177	59	renal	renal	JJ
cord-017142-vx3rgs4r	177	60	failure	failure	NN
cord-017142-vx3rgs4r	177	61	[	[	-LRB-
cord-017142-vx3rgs4r	177	62	53	53	CD
cord-017142-vx3rgs4r	177	63	,	,	,
cord-017142-vx3rgs4r	177	64	88	88	CD
cord-017142-vx3rgs4r	177	65	,	,	,
cord-017142-vx3rgs4r	177	66	100	100	CD
cord-017142-vx3rgs4r	177	67	]	]	-RRB-
cord-017142-vx3rgs4r	177	68	.	.	.
cord-017142-vx3rgs4r	178	1	Bacterial	bacterial	JJ
cord-017142-vx3rgs4r	178	2	infections	infection	NNS
cord-017142-vx3rgs4r	178	3	,	,	,
cord-017142-vx3rgs4r	178	4	especially	especially	RB
cord-017142-vx3rgs4r	178	5	Streptococcus	streptococcus	NN
cord-017142-vx3rgs4r	178	6	pneumoniae	pneumoniae	NN
cord-017142-vx3rgs4r	178	7	,	,	,
cord-017142-vx3rgs4r	178	8	Haemophilus	haemophilus	JJ
cord-017142-vx3rgs4r	178	9	influenzae	influenzae	NN
cord-017142-vx3rgs4r	178	10	,	,	,
cord-017142-vx3rgs4r	178	11	and	and	CC
cord-017142-vx3rgs4r	178	12	Escherichia	escherichia	NN
cord-017142-vx3rgs4r	178	13	coli	coli	NNS
cord-017142-vx3rgs4r	178	14	,	,	,
cord-017142-vx3rgs4r	178	15	tend	tend	VBP
cord-017142-vx3rgs4r	178	16	to	to	TO
cord-017142-vx3rgs4r	178	17	be	be	VB
cord-017142-vx3rgs4r	178	18	the	the	DT
cord-017142-vx3rgs4r	178	19	predominant	predominant	JJ
cord-017142-vx3rgs4r	178	20	organisms	organism	NNS
cord-017142-vx3rgs4r	178	21	causing	cause	VBG
cord-017142-vx3rgs4r	178	22	infection	infection	NN
cord-017142-vx3rgs4r	178	23	at	at	IN
cord-017142-vx3rgs4r	178	24	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	178	25	,	,	,
cord-017142-vx3rgs4r	178	26	while	while	IN
cord-017142-vx3rgs4r	178	27	Staphylococcus	Staphylococcus	NNP
cord-017142-vx3rgs4r	178	28	aureus	aureus	NN
cord-017142-vx3rgs4r	178	29	and	and	CC
cord-017142-vx3rgs4r	178	30	other	other	JJ
cord-017142-vx3rgs4r	178	31	gram	gram	NN
cord-017142-vx3rgs4r	178	32	-	-	HYPH
cord-017142-vx3rgs4r	178	33	negative	negative	JJ
cord-017142-vx3rgs4r	178	34	infections	infection	NNS
cord-017142-vx3rgs4r	178	35	are	be	VBP
cord-017142-vx3rgs4r	178	36	more	more	RBR
cord-017142-vx3rgs4r	178	37	common	common	JJ
cord-017142-vx3rgs4r	178	38	in	in	IN
cord-017142-vx3rgs4r	178	39	the	the	DT
cord-017142-vx3rgs4r	178	40	relapsed	relapse	VBN
cord-017142-vx3rgs4r	178	41	refractory	refractory	JJ
cord-017142-vx3rgs4r	178	42	setting	set	VBG
cord-017142-vx3rgs4r	178	43	[	[	-LRB-
cord-017142-vx3rgs4r	178	44	109	109	CD
cord-017142-vx3rgs4r	178	45	,	,	,
cord-017142-vx3rgs4r	178	46	114	114	CD
cord-017142-vx3rgs4r	178	47	]	]	-RRB-
cord-017142-vx3rgs4r	178	48	.	.	.
cord-017142-vx3rgs4r	179	1	The	the	DT
cord-017142-vx3rgs4r	179	2	use	use	NN
cord-017142-vx3rgs4r	179	3	of	of	IN
cord-017142-vx3rgs4r	179	4	novel	novel	JJ
cord-017142-vx3rgs4r	179	5	drugs	drug	NNS
cord-017142-vx3rgs4r	179	6	combined	combine	VBN
cord-017142-vx3rgs4r	179	7	with	with	IN
cord-017142-vx3rgs4r	179	8	steroids	steroid	NNS
cord-017142-vx3rgs4r	179	9	has	have	VBZ
cord-017142-vx3rgs4r	179	10	increased	increase	VBN
cord-017142-vx3rgs4r	179	11	the	the	DT
cord-017142-vx3rgs4r	179	12	rate	rate	NN
cord-017142-vx3rgs4r	179	13	of	of	IN
cord-017142-vx3rgs4r	179	14	viral	viral	JJ
cord-017142-vx3rgs4r	179	15	and	and	CC
cord-017142-vx3rgs4r	179	16	fungal	fungal	JJ
cord-017142-vx3rgs4r	179	17	infections	infection	NNS
cord-017142-vx3rgs4r	179	18	which	which	WDT
cord-017142-vx3rgs4r	179	19	can	can	MD
cord-017142-vx3rgs4r	179	20	occur	occur	VB
cord-017142-vx3rgs4r	179	21	any	any	DT
cord-017142-vx3rgs4r	179	22	time	time	NN
cord-017142-vx3rgs4r	179	23	during	during	IN
cord-017142-vx3rgs4r	179	24	the	the	DT
cord-017142-vx3rgs4r	179	25	disease	disease	NN
cord-017142-vx3rgs4r	179	26	course	course	NN
cord-017142-vx3rgs4r	179	27	[	[	-LRB-
cord-017142-vx3rgs4r	179	28	12	12	CD
cord-017142-vx3rgs4r	179	29	,	,	,
cord-017142-vx3rgs4r	179	30	58	58	CD
cord-017142-vx3rgs4r	179	31	,	,	,
cord-017142-vx3rgs4r	179	32	91	91	CD
cord-017142-vx3rgs4r	179	33	]	]	-RRB-
cord-017142-vx3rgs4r	179	34	.	.	.
cord-017142-vx3rgs4r	180	1	Viral	viral	JJ
cord-017142-vx3rgs4r	180	2	infections	infection	NNS
cord-017142-vx3rgs4r	180	3	,	,	,
cord-017142-vx3rgs4r	180	4	especially	especially	RB
cord-017142-vx3rgs4r	180	5	herpes	herpes	NN
cord-017142-vx3rgs4r	180	6	simplex	simplex	NNP
cord-017142-vx3rgs4r	180	7	virus	virus	NN
cord-017142-vx3rgs4r	180	8	(	(	-LRB-
cord-017142-vx3rgs4r	180	9	HSV	HSV	NNP
cord-017142-vx3rgs4r	180	10	)	)	-RRB-
cord-017142-vx3rgs4r	180	11	and	and	CC
cord-017142-vx3rgs4r	180	12	varicella	varicella	NN
cord-017142-vx3rgs4r	180	13	-	-	HYPH
cord-017142-vx3rgs4r	180	14	zoster	zoster	NN
cord-017142-vx3rgs4r	180	15	virus	virus	NN
cord-017142-vx3rgs4r	180	16	(	(	-LRB-
cord-017142-vx3rgs4r	180	17	VZV	VZV	NNP
cord-017142-vx3rgs4r	180	18	)	)	-RRB-
cord-017142-vx3rgs4r	180	19	,	,	,
cord-017142-vx3rgs4r	180	20	have	have	VBP
cord-017142-vx3rgs4r	180	21	increased	increase	VBN
cord-017142-vx3rgs4r	180	22	in	in	IN
cord-017142-vx3rgs4r	180	23	incidence	incidence	NN
cord-017142-vx3rgs4r	180	24	with	with	IN
cord-017142-vx3rgs4r	180	25	the	the	DT
cord-017142-vx3rgs4r	180	26	introduction	introduction	NN
cord-017142-vx3rgs4r	180	27	of	of	IN
cord-017142-vx3rgs4r	180	28	proteasome	proteasome	NN
cord-017142-vx3rgs4r	180	29	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	180	30	such	such	JJ
cord-017142-vx3rgs4r	180	31	as	as	IN
cord-017142-vx3rgs4r	180	32	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	180	33	.	.	.
cord-017142-vx3rgs4r	181	1	Viral	viral	JJ
cord-017142-vx3rgs4r	181	2	prophylaxis	prophylaxis	NN
cord-017142-vx3rgs4r	181	3	with	with	IN
cord-017142-vx3rgs4r	181	4	acyclovir	acyclovir	NNP
cord-017142-vx3rgs4r	181	5	or	or	CC
cord-017142-vx3rgs4r	181	6	valacyclovir	valacyclovir	NNP
cord-017142-vx3rgs4r	181	7	is	be	VBZ
cord-017142-vx3rgs4r	181	8	recommended	recommend	VBN
cord-017142-vx3rgs4r	181	9	in	in	IN
cord-017142-vx3rgs4r	181	10	all	all	DT
cord-017142-vx3rgs4r	181	11	patients	patient	NNS
cord-017142-vx3rgs4r	181	12	undergoing	undergo	VBG
cord-017142-vx3rgs4r	181	13	therapy	therapy	NN
cord-017142-vx3rgs4r	181	14	with	with	IN
cord-017142-vx3rgs4r	181	15	proteasome	proteasome	NN
cord-017142-vx3rgs4r	181	16	inhibitors	inhibitor	NNS
cord-017142-vx3rgs4r	181	17	or	or	CC
cord-017142-vx3rgs4r	181	18	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	181	19	antibodies	antibody	NNS
cord-017142-vx3rgs4r	181	20	.	.	.
cord-017142-vx3rgs4r	182	1	Although	although	IN
cord-017142-vx3rgs4r	182	2	invasive	invasive	JJ
cord-017142-vx3rgs4r	182	3	fungal	fungal	NN
cord-017142-vx3rgs4r	182	4	infection	infection	NN
cord-017142-vx3rgs4r	182	5	(	(	-LRB-
cord-017142-vx3rgs4r	182	6	approximately	approximately	RB
cord-017142-vx3rgs4r	182	7	2	2	CD
cord-017142-vx3rgs4r	182	8	-	-	SYM
cord-017142-vx3rgs4r	182	9	3	3	CD
cord-017142-vx3rgs4r	182	10	%	%	NN
cord-017142-vx3rgs4r	182	11	)	)	-RRB-
cord-017142-vx3rgs4r	182	12	incidence	incidence	NN
cord-017142-vx3rgs4r	182	13	is	be	VBZ
cord-017142-vx3rgs4r	182	14	low	low	JJ
cord-017142-vx3rgs4r	182	15	,	,	,
cord-017142-vx3rgs4r	182	16	the	the	DT
cord-017142-vx3rgs4r	182	17	mortality	mortality	NN
cord-017142-vx3rgs4r	182	18	rate	rate	NN
cord-017142-vx3rgs4r	182	19	is	be	VBZ
cord-017142-vx3rgs4r	182	20	high	high	JJ
cord-017142-vx3rgs4r	182	21	with	with	IN
cord-017142-vx3rgs4r	182	22	approximately	approximately	RB
cord-017142-vx3rgs4r	182	23	60	60	CD
cord-017142-vx3rgs4r	182	24	%	%	NN
cord-017142-vx3rgs4r	182	25	of	of	IN
cord-017142-vx3rgs4r	182	26	patients	patient	NNS
cord-017142-vx3rgs4r	182	27	requiring	require	VBG
cord-017142-vx3rgs4r	182	28	ICU	ICU	NNP
cord-017142-vx3rgs4r	182	29	management	management	NN
cord-017142-vx3rgs4r	182	30	.	.	.
cord-017142-vx3rgs4r	183	1	The	the	DT
cord-017142-vx3rgs4r	183	2	introduction	introduction	NN
cord-017142-vx3rgs4r	183	3	of	of	IN
cord-017142-vx3rgs4r	183	4	novel	novel	JJ
cord-017142-vx3rgs4r	183	5	agents	agent	NNS
cord-017142-vx3rgs4r	183	6	tends	tend	VBZ
cord-017142-vx3rgs4r	183	7	to	to	TO
cord-017142-vx3rgs4r	183	8	be	be	VB
cord-017142-vx3rgs4r	183	9	associated	associate	VBN
cord-017142-vx3rgs4r	183	10	with	with	IN
cord-017142-vx3rgs4r	183	11	later	later	JJ
cord-017142-vx3rgs4r	183	12	-	-	HYPH
cord-017142-vx3rgs4r	183	13	onset	onset	NN
cord-017142-vx3rgs4r	183	14	invasive	invasive	JJ
cord-017142-vx3rgs4r	183	15	fungal	fungal	JJ
cord-017142-vx3rgs4r	183	16	infections	infection	NNS
cord-017142-vx3rgs4r	183	17	compared	compare	VBN
cord-017142-vx3rgs4r	183	18	to	to	IN
cord-017142-vx3rgs4r	183	19	studies	study	NNS
cord-017142-vx3rgs4r	183	20	from	from	IN
cord-017142-vx3rgs4r	183	21	the	the	DT
cord-017142-vx3rgs4r	183	22	conventional	conventional	JJ
cord-017142-vx3rgs4r	183	23	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	183	24	era	era	NN
cord-017142-vx3rgs4r	183	25	where	where	WRB
cord-017142-vx3rgs4r	183	26	an	an	DT
cord-017142-vx3rgs4r	183	27	earlier	early	JJR
cord-017142-vx3rgs4r	183	28	onset	onset	NN
cord-017142-vx3rgs4r	183	29	was	be	VBD
cord-017142-vx3rgs4r	183	30	noted	note	VBN
cord-017142-vx3rgs4r	183	31	[	[	-LRB-
cord-017142-vx3rgs4r	183	32	122	122	CD
cord-017142-vx3rgs4r	183	33	]	]	-RRB-
cord-017142-vx3rgs4r	183	34	.	.	.
cord-017142-vx3rgs4r	184	1	Furthermore	furthermore	RB
cord-017142-vx3rgs4r	184	2	the	the	DT
cord-017142-vx3rgs4r	184	3	use	use	NN
cord-017142-vx3rgs4r	184	4	of	of	IN
cord-017142-vx3rgs4r	184	5	long	long	JJ
cord-017142-vx3rgs4r	184	6	-	-	HYPH
cord-017142-vx3rgs4r	184	7	term	term	NN
cord-017142-vx3rgs4r	184	8	and	and	CC
cord-017142-vx3rgs4r	184	9	high	high	JJ
cord-017142-vx3rgs4r	184	10	-	-	HYPH
cord-017142-vx3rgs4r	184	11	dose	dose	NN
cord-017142-vx3rgs4r	184	12	dexamethasone	dexamethasone	NN
cord-017142-vx3rgs4r	184	13	can	can	MD
cord-017142-vx3rgs4r	184	14	cause	cause	VB
cord-017142-vx3rgs4r	184	15	persistent	persistent	JJ
cord-017142-vx3rgs4r	184	16	defect	defect	NN
cord-017142-vx3rgs4r	184	17	in	in	IN
cord-017142-vx3rgs4r	184	18	T	T	NNP
cord-017142-vx3rgs4r	184	19	cell	cell	NN
cord-017142-vx3rgs4r	184	20	-	-	HYPH
cord-017142-vx3rgs4r	184	21	mediated	mediate	VBN
cord-017142-vx3rgs4r	184	22	immunity	immunity	NN
cord-017142-vx3rgs4r	184	23	which	which	WDT
cord-017142-vx3rgs4r	184	24	predisposes	predispose	VBZ
cord-017142-vx3rgs4r	184	25	patients	patient	NNS
cord-017142-vx3rgs4r	184	26	to	to	IN
cord-017142-vx3rgs4r	184	27	mucosal	mucosal	JJ
cord-017142-vx3rgs4r	184	28	candidiasis	candidiasi	NNS
cord-017142-vx3rgs4r	184	29	,	,	,
cord-017142-vx3rgs4r	184	30	P.	P.	NNP
cord-017142-vx3rgs4r	184	31	jirovecii	jirovecii	NNP
cord-017142-vx3rgs4r	184	32	,	,	,
cord-017142-vx3rgs4r	184	33	HSV	HSV	NNP
cord-017142-vx3rgs4r	184	34	,	,	,
cord-017142-vx3rgs4r	184	35	and	and	CC
cord-017142-vx3rgs4r	184	36	VZV	VZV	NNP
cord-017142-vx3rgs4r	184	37	infections	infection	NNS
cord-017142-vx3rgs4r	184	38	.	.	.
cord-017142-vx3rgs4r	185	1	Following	follow	VBG
cord-017142-vx3rgs4r	185	2	sepsis	sepsis	NN
cord-017142-vx3rgs4r	185	3	guidelines	guideline	NNS
cord-017142-vx3rgs4r	185	4	with	with	IN
cord-017142-vx3rgs4r	185	5	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	185	6	fluid	fluid	JJ
cord-017142-vx3rgs4r	185	7	resuscitation	resuscitation	NN
cord-017142-vx3rgs4r	185	8	and	and	CC
cord-017142-vx3rgs4r	185	9	broad	broad	JJ
cord-017142-vx3rgs4r	185	10	-	-	HYPH
cord-017142-vx3rgs4r	185	11	spectrum	spectrum	NN
cord-017142-vx3rgs4r	185	12	antibiotic	antibiotic	JJ
cord-017142-vx3rgs4r	185	13	coverage	coverage	NN
cord-017142-vx3rgs4r	185	14	as	as	RB
cord-017142-vx3rgs4r	185	15	well	well	RB
cord-017142-vx3rgs4r	185	16	as	as	IN
cord-017142-vx3rgs4r	185	17	growth	growth	NN
cord-017142-vx3rgs4r	185	18	factor	factor	NN
cord-017142-vx3rgs4r	185	19	support	support	NN
cord-017142-vx3rgs4r	185	20	if	if	IN
cord-017142-vx3rgs4r	185	21	neutropenic	neutropenic	JJ
cord-017142-vx3rgs4r	185	22	is	be	VBZ
cord-017142-vx3rgs4r	185	23	warranted	warrant	VBN
cord-017142-vx3rgs4r	185	24	in	in	IN
cord-017142-vx3rgs4r	185	25	a	a	DT
cord-017142-vx3rgs4r	185	26	patient	patient	NN
cord-017142-vx3rgs4r	185	27	presenting	present	VBG
cord-017142-vx3rgs4r	185	28	with	with	IN
cord-017142-vx3rgs4r	185	29	suspected	suspect	VBN
cord-017142-vx3rgs4r	185	30	sepsis	sepsis	NN
cord-017142-vx3rgs4r	185	31	/	/	SYM
cord-017142-vx3rgs4r	185	32	infection	infection	NN
cord-017142-vx3rgs4r	185	33	.	.	.
cord-017142-vx3rgs4r	186	1	In	in	IN
cord-017142-vx3rgs4r	186	2	case	case	NN
cord-017142-vx3rgs4r	186	3	of	of	IN
cord-017142-vx3rgs4r	186	4	clinical	clinical	JJ
cord-017142-vx3rgs4r	186	5	deterioration	deterioration	NN
cord-017142-vx3rgs4r	186	6	with	with	IN
cord-017142-vx3rgs4r	186	7	unclear	unclear	JJ
cord-017142-vx3rgs4r	186	8	source	source	NN
cord-017142-vx3rgs4r	186	9	of	of	IN
cord-017142-vx3rgs4r	186	10	infection	infection	NN
cord-017142-vx3rgs4r	186	11	,	,	,
cord-017142-vx3rgs4r	186	12	persistent	persistent	JJ
cord-017142-vx3rgs4r	186	13	febrile	febrile	JJ
cord-017142-vx3rgs4r	186	14	neutropenia	neutropenia	NN
cord-017142-vx3rgs4r	186	15	,	,	,
cord-017142-vx3rgs4r	186	16	or	or	CC
cord-017142-vx3rgs4r	186	17	hemodynamic	hemodynamic	JJ
cord-017142-vx3rgs4r	186	18	compromise	compromise	NN
cord-017142-vx3rgs4r	186	19	,	,	,
cord-017142-vx3rgs4r	186	20	consider	consider	VB
cord-017142-vx3rgs4r	186	21	computer	computer	NN
cord-017142-vx3rgs4r	186	22	tomography	tomography	NN
cord-017142-vx3rgs4r	186	23	(	(	-LRB-
cord-017142-vx3rgs4r	186	24	CT	CT	NNP
cord-017142-vx3rgs4r	186	25	)	)	-RRB-
cord-017142-vx3rgs4r	186	26	scan	scan	VBP
cord-017142-vx3rgs4r	186	27	including	include	VBG
cord-017142-vx3rgs4r	186	28	sinus	sinus	NN
cord-017142-vx3rgs4r	186	29	imaging	imaging	NN
cord-017142-vx3rgs4r	186	30	.	.	.
cord-017142-vx3rgs4r	187	1	Other	other	JJ
cord-017142-vx3rgs4r	187	2	investigative	investigative	JJ
cord-017142-vx3rgs4r	187	3	modalities	modality	NNS
cord-017142-vx3rgs4r	187	4	for	for	IN
cord-017142-vx3rgs4r	187	5	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	187	6	should	should	MD
cord-017142-vx3rgs4r	187	7	include	include	VB
cord-017142-vx3rgs4r	187	8	bronchoscopy	bronchoscopy	NN
cord-017142-vx3rgs4r	187	9	/	/	SYM
cord-017142-vx3rgs4r	187	10	BAL	bal	NN
cord-017142-vx3rgs4r	187	11	with	with	IN
cord-017142-vx3rgs4r	187	12	microscopy	microscopy	NNS
cord-017142-vx3rgs4r	187	13	and	and	CC
cord-017142-vx3rgs4r	187	14	bacteria	bacteria	NNS
cord-017142-vx3rgs4r	187	15	,	,	,
cord-017142-vx3rgs4r	187	16	viral	viral	JJ
cord-017142-vx3rgs4r	187	17	,	,	,
cord-017142-vx3rgs4r	187	18	and	and	CC
cord-017142-vx3rgs4r	187	19	fungal	fungal	JJ
cord-017142-vx3rgs4r	187	20	culture	culture	NN
cord-017142-vx3rgs4r	187	21	.	.	.
cord-017142-vx3rgs4r	188	1	In	in	IN
cord-017142-vx3rgs4r	188	2	suspected	suspect	VBN
cord-017142-vx3rgs4r	188	3	cases	case	NNS
cord-017142-vx3rgs4r	188	4	of	of	IN
cord-017142-vx3rgs4r	188	5	fungal	fungal	JJ
cord-017142-vx3rgs4r	188	6	infection	infection	NN
cord-017142-vx3rgs4r	188	7	,	,	,
cord-017142-vx3rgs4r	188	8	Aspergillus	Aspergillus	NNP
cord-017142-vx3rgs4r	188	9	PCR	PCR	NNP
cord-017142-vx3rgs4r	188	10	and	and	CC
cord-017142-vx3rgs4r	188	11	galactomannan	galactomannan	NNP
cord-017142-vx3rgs4r	188	12	testing	testing	NN
cord-017142-vx3rgs4r	188	13	on	on	IN
cord-017142-vx3rgs4r	188	14	serum	serum	NN
cord-017142-vx3rgs4r	188	15	and	and	CC
cord-017142-vx3rgs4r	188	16	BAL	bal	NN
cord-017142-vx3rgs4r	188	17	should	should	MD
cord-017142-vx3rgs4r	188	18	be	be	VB
cord-017142-vx3rgs4r	188	19	performed	perform	VBN
cord-017142-vx3rgs4r	188	20	.	.	.
cord-017142-vx3rgs4r	189	1	Due	due	IN
cord-017142-vx3rgs4r	189	2	to	to	IN
cord-017142-vx3rgs4r	189	3	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	189	4	immunodeficiency	immunodeficiency	NN
cord-017142-vx3rgs4r	189	5	,	,	,
cord-017142-vx3rgs4r	189	6	treatment	treatment	NN
cord-017142-vx3rgs4r	189	7	with	with	IN
cord-017142-vx3rgs4r	189	8	intravenous	intravenous	JJ
cord-017142-vx3rgs4r	189	9	immunoglobulins	immunoglobulin	NNS
cord-017142-vx3rgs4r	189	10	is	be	VBZ
cord-017142-vx3rgs4r	189	11	considered	consider	VBN
cord-017142-vx3rgs4r	189	12	in	in	IN
cord-017142-vx3rgs4r	189	13	patients	patient	NNS
cord-017142-vx3rgs4r	189	14	with	with	IN
cord-017142-vx3rgs4r	189	15	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	189	16	bacterial	bacterial	JJ
cord-017142-vx3rgs4r	189	17	or	or	CC
cord-017142-vx3rgs4r	189	18	viral	viral	JJ
cord-017142-vx3rgs4r	189	19	infections	infection	NNS
cord-017142-vx3rgs4r	189	20	;	;	:
cord-017142-vx3rgs4r	189	21	however	however	RB
cord-017142-vx3rgs4r	189	22	its	-PRON-	PRP$
cord-017142-vx3rgs4r	189	23	role	role	NN
cord-017142-vx3rgs4r	189	24	in	in	IN
cord-017142-vx3rgs4r	189	25	treating	treat	VBG
cord-017142-vx3rgs4r	189	26	an	an	DT
cord-017142-vx3rgs4r	189	27	acute	acute	JJ
cord-017142-vx3rgs4r	189	28	infection	infection	NN
cord-017142-vx3rgs4r	189	29	is	be	VBZ
cord-017142-vx3rgs4r	189	30	limited	limit	VBN
cord-017142-vx3rgs4r	189	31	.	.	.
cord-017142-vx3rgs4r	190	1	Direct	direct	JJ
cord-017142-vx3rgs4r	190	2	involvement	involvement	NN
cord-017142-vx3rgs4r	190	3	of	of	IN
cord-017142-vx3rgs4r	190	4	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	190	5	parenchyma	parenchyma	NN
cord-017142-vx3rgs4r	190	6	in	in	IN
cord-017142-vx3rgs4r	190	7	MM	MM	NNP
cord-017142-vx3rgs4r	190	8	is	be	VBZ
cord-017142-vx3rgs4r	190	9	extremely	extremely	RB
cord-017142-vx3rgs4r	190	10	rare	rare	JJ
cord-017142-vx3rgs4r	190	11	.	.	.
cord-017142-vx3rgs4r	191	1	Pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	191	2	complications	complication	NNS
cord-017142-vx3rgs4r	191	3	can	can	MD
cord-017142-vx3rgs4r	191	4	arise	arise	VB
cord-017142-vx3rgs4r	191	5	from	from	IN
cord-017142-vx3rgs4r	191	6	a	a	DT
cord-017142-vx3rgs4r	191	7	broad	broad	JJ
cord-017142-vx3rgs4r	191	8	range	range	NN
cord-017142-vx3rgs4r	191	9	of	of	IN
cord-017142-vx3rgs4r	191	10	different	different	JJ
cord-017142-vx3rgs4r	191	11	mechanisms	mechanism	NNS
cord-017142-vx3rgs4r	191	12	both	both	CC
cord-017142-vx3rgs4r	191	13	infectious	infectious	JJ
cord-017142-vx3rgs4r	191	14	and	and	CC
cord-017142-vx3rgs4r	191	15	noninfectious	noninfectious	JJ
cord-017142-vx3rgs4r	191	16	.	.	.
cord-017142-vx3rgs4r	192	1	In	in	IN
cord-017142-vx3rgs4r	192	2	majority	majority	NN
cord-017142-vx3rgs4r	192	3	of	of	IN
cord-017142-vx3rgs4r	192	4	the	the	DT
cord-017142-vx3rgs4r	192	5	cases	case	NNS
cord-017142-vx3rgs4r	192	6	presenting	present	VBG
cord-017142-vx3rgs4r	192	7	with	with	IN
cord-017142-vx3rgs4r	192	8	respiratory	respiratory	JJ
cord-017142-vx3rgs4r	192	9	failure	failure	NN
cord-017142-vx3rgs4r	192	10	,	,	,
cord-017142-vx3rgs4r	192	11	the	the	DT
cord-017142-vx3rgs4r	192	12	etiology	etiology	NN
cord-017142-vx3rgs4r	192	13	is	be	VBZ
cord-017142-vx3rgs4r	192	14	infectious	infectious	JJ
cord-017142-vx3rgs4r	192	15	.	.	.
cord-017142-vx3rgs4r	193	1	Patients	patient	NNS
cord-017142-vx3rgs4r	193	2	with	with	IN
cord-017142-vx3rgs4r	193	3	myeloma	myeloma	NN
cord-017142-vx3rgs4r	193	4	can	can	MD
cord-017142-vx3rgs4r	193	5	present	present	VB
cord-017142-vx3rgs4r	193	6	with	with	IN
cord-017142-vx3rgs4r	193	7	lung	lung	NN
cord-017142-vx3rgs4r	193	8	infiltrates	infiltrate	NNS
cord-017142-vx3rgs4r	193	9	,	,	,
cord-017142-vx3rgs4r	193	10	ground	ground	NN
cord-017142-vx3rgs4r	193	11	glass	glass	NN
cord-017142-vx3rgs4r	193	12	opacities	opacity	NNS
cord-017142-vx3rgs4r	193	13	,	,	,
cord-017142-vx3rgs4r	193	14	nodules	nodule	NNS
cord-017142-vx3rgs4r	193	15	,	,	,
cord-017142-vx3rgs4r	193	16	masses	masse	NNS
cord-017142-vx3rgs4r	193	17	,	,	,
cord-017142-vx3rgs4r	193	18	effusion	effusion	NN
cord-017142-vx3rgs4r	193	19	,	,	,
cord-017142-vx3rgs4r	193	20	and	and	CC
cord-017142-vx3rgs4r	193	21	lymphadenopathy	lymphadenopathy	JJ
cord-017142-vx3rgs4r	193	22	.	.	.
cord-017142-vx3rgs4r	194	1	Noninfectious	noninfectious	JJ
cord-017142-vx3rgs4r	194	2	causes	cause	NNS
cord-017142-vx3rgs4r	194	3	that	that	WDT
cord-017142-vx3rgs4r	194	4	need	need	VBP
cord-017142-vx3rgs4r	194	5	to	to	TO
cord-017142-vx3rgs4r	194	6	be	be	VB
cord-017142-vx3rgs4r	194	7	ruled	rule	VBN
cord-017142-vx3rgs4r	194	8	out	out	RP
cord-017142-vx3rgs4r	194	9	include	include	VBP
cord-017142-vx3rgs4r	194	10	congestive	congestive	JJ
cord-017142-vx3rgs4r	194	11	heart	heart	NN
cord-017142-vx3rgs4r	194	12	failure	failure	NN
cord-017142-vx3rgs4r	194	13	,	,	,
cord-017142-vx3rgs4r	194	14	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	194	15	embolism	embolism	NN
cord-017142-vx3rgs4r	194	16	,	,	,
cord-017142-vx3rgs4r	194	17	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	194	18	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	194	19	,	,	,
cord-017142-vx3rgs4r	194	20	and	and	CC
cord-017142-vx3rgs4r	194	21	drug	drug	NN
cord-017142-vx3rgs4r	194	22	-	-	HYPH
cord-017142-vx3rgs4r	194	23	induced	induce	VBN
cord-017142-vx3rgs4r	194	24	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	194	25	.	.	.
cord-017142-vx3rgs4r	195	1	Myeloma	myeloma	NN
cord-017142-vx3rgs4r	195	2	lung	lung	NN
cord-017142-vx3rgs4r	195	3	:	:	:
cord-017142-vx3rgs4r	196	1	Case	case	NN
cord-017142-vx3rgs4r	196	2	reports	report	NNS
cord-017142-vx3rgs4r	196	3	and	and	CC
cord-017142-vx3rgs4r	196	4	case	case	NN
cord-017142-vx3rgs4r	196	5	series	serie	NNS
cord-017142-vx3rgs4r	196	6	describe	describe	VBP
cord-017142-vx3rgs4r	196	7	the	the	DT
cord-017142-vx3rgs4r	196	8	various	various	JJ
cord-017142-vx3rgs4r	196	9	ways	way	NNS
cord-017142-vx3rgs4r	196	10	MM	MM	NNP
cord-017142-vx3rgs4r	196	11	can	can	MD
cord-017142-vx3rgs4r	196	12	involve	involve	VB
cord-017142-vx3rgs4r	196	13	the	the	DT
cord-017142-vx3rgs4r	196	14	lung	lung	NN
cord-017142-vx3rgs4r	196	15	.	.	.
cord-017142-vx3rgs4r	197	1	Presentation	presentation	NN
cord-017142-vx3rgs4r	197	2	of	of	IN
cord-017142-vx3rgs4r	197	3	lung	lung	NN
cord-017142-vx3rgs4r	197	4	disease	disease	NN
cord-017142-vx3rgs4r	197	5	is	be	VBZ
cord-017142-vx3rgs4r	197	6	variable	variable	JJ
cord-017142-vx3rgs4r	197	7	and	and	CC
cord-017142-vx3rgs4r	197	8	includes	include	VBZ
cord-017142-vx3rgs4r	197	9	consolidative	consolidative	JJ
cord-017142-vx3rgs4r	197	10	or	or	CC
cord-017142-vx3rgs4r	197	11	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	197	12	pattern	pattern	NN
cord-017142-vx3rgs4r	197	13	infiltrates	infiltrate	VBZ
cord-017142-vx3rgs4r	197	14	on	on	IN
cord-017142-vx3rgs4r	197	15	imaging	image	VBG
cord-017142-vx3rgs4r	197	16	,	,	,
cord-017142-vx3rgs4r	197	17	intraparenchymal	intraparenchymal	NNP
cord-017142-vx3rgs4r	197	18	plasmacytomas	plasmacytomas	NNP
cord-017142-vx3rgs4r	197	19	,	,	,
cord-017142-vx3rgs4r	197	20	intrapulmonary	intrapulmonary	JJ
cord-017142-vx3rgs4r	197	21	calcifications	calcification	NNS
cord-017142-vx3rgs4r	197	22	,	,	,
cord-017142-vx3rgs4r	197	23	or	or	CC
cord-017142-vx3rgs4r	197	24	pleural	pleural	JJ
cord-017142-vx3rgs4r	197	25	effusions	effusion	NNS
cord-017142-vx3rgs4r	197	26	[	[	-LRB-
cord-017142-vx3rgs4r	197	27	60	60	CD
cord-017142-vx3rgs4r	197	28	,	,	,
cord-017142-vx3rgs4r	197	29	73	73	CD
cord-017142-vx3rgs4r	197	30	,	,	,
cord-017142-vx3rgs4r	197	31	139	139	CD
cord-017142-vx3rgs4r	197	32	]	]	-RRB-
cord-017142-vx3rgs4r	197	33	.	.	.
cord-017142-vx3rgs4r	198	1	Presentations	presentation	NNS
cord-017142-vx3rgs4r	198	2	similar	similar	JJ
cord-017142-vx3rgs4r	198	3	to	to	IN
cord-017142-vx3rgs4r	198	4	ARDS	ARDS	NNP
cord-017142-vx3rgs4r	198	5	have	have	VBP
cord-017142-vx3rgs4r	198	6	also	also	RB
cord-017142-vx3rgs4r	198	7	been	be	VBN
cord-017142-vx3rgs4r	198	8	reported	report	VBN
cord-017142-vx3rgs4r	198	9	[	[	-LRB-
cord-017142-vx3rgs4r	198	10	40	40	CD
cord-017142-vx3rgs4r	198	11	,	,	,
cord-017142-vx3rgs4r	198	12	80	80	CD
cord-017142-vx3rgs4r	198	13	,	,	,
cord-017142-vx3rgs4r	198	14	99	99	CD
cord-017142-vx3rgs4r	198	15	,	,	,
cord-017142-vx3rgs4r	198	16	106	106	CD
cord-017142-vx3rgs4r	198	17	,	,	,
cord-017142-vx3rgs4r	198	18	134	134	CD
cord-017142-vx3rgs4r	198	19	]	]	-RRB-
cord-017142-vx3rgs4r	198	20	.	.	.
cord-017142-vx3rgs4r	199	1	A	a	DT
cord-017142-vx3rgs4r	199	2	high	high	JJ
cord-017142-vx3rgs4r	199	3	index	index	NN
cord-017142-vx3rgs4r	199	4	of	of	IN
cord-017142-vx3rgs4r	199	5	suspicion	suspicion	NN
cord-017142-vx3rgs4r	199	6	is	be	VBZ
cord-017142-vx3rgs4r	199	7	required	require	VBN
cord-017142-vx3rgs4r	199	8	as	as	IN
cord-017142-vx3rgs4r	199	9	there	there	EX
cord-017142-vx3rgs4r	199	10	is	be	VBZ
cord-017142-vx3rgs4r	199	11	a	a	DT
cord-017142-vx3rgs4r	199	12	broad	broad	JJ
cord-017142-vx3rgs4r	199	13	differential	differential	NN
cord-017142-vx3rgs4r	199	14	of	of	IN
cord-017142-vx3rgs4r	199	15	diagnoses	diagnosis	NNS
cord-017142-vx3rgs4r	199	16	with	with	IN
cord-017142-vx3rgs4r	199	17	similar	similar	JJ
cord-017142-vx3rgs4r	199	18	radiographic	radiographic	JJ
cord-017142-vx3rgs4r	199	19	findings	finding	NNS
cord-017142-vx3rgs4r	199	20	.	.	.
cord-017142-vx3rgs4r	200	1	Patients	patient	NNS
cord-017142-vx3rgs4r	200	2	with	with	IN
cord-017142-vx3rgs4r	200	3	extramedullary	extramedullary	JJ
cord-017142-vx3rgs4r	200	4	MM	MM	NNP
cord-017142-vx3rgs4r	200	5	tend	tend	VBP
cord-017142-vx3rgs4r	200	6	to	to	TO
cord-017142-vx3rgs4r	200	7	have	have	VB
cord-017142-vx3rgs4r	200	8	more	more	RBR
cord-017142-vx3rgs4r	200	9	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	200	10	disease	disease	NN
cord-017142-vx3rgs4r	200	11	and	and	CC
cord-017142-vx3rgs4r	200	12	can	can	MD
cord-017142-vx3rgs4r	200	13	deteriorate	deteriorate	VB
cord-017142-vx3rgs4r	200	14	rapidly	rapidly	RB
cord-017142-vx3rgs4r	200	15	due	due	IN
cord-017142-vx3rgs4r	200	16	to	to	IN
cord-017142-vx3rgs4r	200	17	disease	disease	NN
cord-017142-vx3rgs4r	200	18	progression	progression	NN
cord-017142-vx3rgs4r	200	19	if	if	IN
cord-017142-vx3rgs4r	200	20	not	not	RB
cord-017142-vx3rgs4r	200	21	recognized	recognize	VBN
cord-017142-vx3rgs4r	200	22	and	and	CC
cord-017142-vx3rgs4r	200	23	treated	treat	VBN
cord-017142-vx3rgs4r	200	24	early	early	RB
cord-017142-vx3rgs4r	200	25	.	.	.
cord-017142-vx3rgs4r	201	1	If	if	IN
cord-017142-vx3rgs4r	201	2	there	there	EX
cord-017142-vx3rgs4r	201	3	is	be	VBZ
cord-017142-vx3rgs4r	201	4	evidence	evidence	NN
cord-017142-vx3rgs4r	201	5	of	of	IN
cord-017142-vx3rgs4r	201	6	MM	MM	NNP
cord-017142-vx3rgs4r	201	7	progression	progression	NN
cord-017142-vx3rgs4r	201	8	on	on	IN
cord-017142-vx3rgs4r	201	9	blood	blood	NN
cord-017142-vx3rgs4r	201	10	tests	test	NNS
cord-017142-vx3rgs4r	201	11	or	or	CC
cord-017142-vx3rgs4r	201	12	bone	bone	NN
cord-017142-vx3rgs4r	201	13	marrow	marrow	NN
cord-017142-vx3rgs4r	201	14	,	,	,
cord-017142-vx3rgs4r	201	15	a	a	DT
cord-017142-vx3rgs4r	201	16	biopsy	biopsy	NN
cord-017142-vx3rgs4r	201	17	(	(	-LRB-
cord-017142-vx3rgs4r	201	18	surgical	surgical	JJ
cord-017142-vx3rgs4r	201	19	,	,	,
cord-017142-vx3rgs4r	201	20	transbronchial	transbronchial	NN
cord-017142-vx3rgs4r	201	21	)	)	-RRB-
cord-017142-vx3rgs4r	201	22	or	or	CC
cord-017142-vx3rgs4r	201	23	bronchoscopy	bronchoscopy	VB
cord-017142-vx3rgs4r	201	24	with	with	IN
cord-017142-vx3rgs4r	201	25	aspiration	aspiration	NN
cord-017142-vx3rgs4r	201	26	and/or	and/or	CC
cord-017142-vx3rgs4r	201	27	bronchoalveolar	bronchoalveolar	NNP
cord-017142-vx3rgs4r	201	28	lavage	lavage	NNP
cord-017142-vx3rgs4r	201	29	(	(	-LRB-
cord-017142-vx3rgs4r	201	30	BAL	BAL	NNP
cord-017142-vx3rgs4r	201	31	)	)	-RRB-
cord-017142-vx3rgs4r	201	32	should	should	MD
cord-017142-vx3rgs4r	201	33	be	be	VB
cord-017142-vx3rgs4r	201	34	strongly	strongly	RB
cord-017142-vx3rgs4r	201	35	considered	consider	VBN
cord-017142-vx3rgs4r	201	36	with	with	IN
cord-017142-vx3rgs4r	201	37	microbiologic	microbiologic	NNP
cord-017142-vx3rgs4r	201	38	and	and	CC
cord-017142-vx3rgs4r	201	39	flow	flow	NN
cord-017142-vx3rgs4r	201	40	cytometric	cytometric	NNP
cord-017142-vx3rgs4r	201	41	analysis	analysis	NN
cord-017142-vx3rgs4r	201	42	.	.	.
cord-017142-vx3rgs4r	202	1	Once	once	IN
cord-017142-vx3rgs4r	202	2	infection	infection	NN
cord-017142-vx3rgs4r	202	3	is	be	VBZ
cord-017142-vx3rgs4r	202	4	excluded	exclude	VBN
cord-017142-vx3rgs4r	202	5	and	and	CC
cord-017142-vx3rgs4r	202	6	evidence	evidence	NN
cord-017142-vx3rgs4r	202	7	of	of	IN
cord-017142-vx3rgs4r	202	8	progression	progression	NN
cord-017142-vx3rgs4r	202	9	is	be	VBZ
cord-017142-vx3rgs4r	202	10	confirmed	confirm	VBN
cord-017142-vx3rgs4r	202	11	,	,	,
cord-017142-vx3rgs4r	202	12	prompt	prompt	JJ
cord-017142-vx3rgs4r	202	13	initiation	initiation	NN
cord-017142-vx3rgs4r	202	14	of	of	IN
cord-017142-vx3rgs4r	202	15	MM	MM	NNP
cord-017142-vx3rgs4r	202	16	directed	direct	VBN
cord-017142-vx3rgs4r	202	17	therapy	therapy	NN
cord-017142-vx3rgs4r	202	18	is	be	VBZ
cord-017142-vx3rgs4r	202	19	warranted	warrant	VBN
cord-017142-vx3rgs4r	202	20	[	[	-LRB-
cord-017142-vx3rgs4r	202	21	62	62	CD
cord-017142-vx3rgs4r	202	22	]	]	-RRB-
cord-017142-vx3rgs4r	202	23	.	.	.
cord-017142-vx3rgs4r	203	1	Diffuse	diffuse	JJ
cord-017142-vx3rgs4r	203	2	alveolar	alveolar	NN
cord-017142-vx3rgs4r	203	3	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	203	4	:	:	:
cord-017142-vx3rgs4r	204	1	In	in	IN
cord-017142-vx3rgs4r	204	2	patients	patient	NNS
cord-017142-vx3rgs4r	204	3	presenting	present	VBG
cord-017142-vx3rgs4r	204	4	with	with	IN
cord-017142-vx3rgs4r	204	5	acute	acute	JJ
cord-017142-vx3rgs4r	204	6	onset	onset	NN
cord-017142-vx3rgs4r	204	7	hypoxia	hypoxia	NN
cord-017142-vx3rgs4r	204	8	,	,	,
cord-017142-vx3rgs4r	204	9	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	204	10	opacities	opacity	NNS
cord-017142-vx3rgs4r	204	11	,	,	,
cord-017142-vx3rgs4r	204	12	and	and	CC
cord-017142-vx3rgs4r	204	13	fevers	fever	NNS
cord-017142-vx3rgs4r	204	14	,	,	,
cord-017142-vx3rgs4r	204	15	especially	especially	RB
cord-017142-vx3rgs4r	204	16	in	in	IN
cord-017142-vx3rgs4r	204	17	the	the	DT
cord-017142-vx3rgs4r	204	18	setting	setting	NN
cord-017142-vx3rgs4r	204	19	of	of	IN
cord-017142-vx3rgs4r	204	20	thrombocytopenia	thrombocytopenia	NN
cord-017142-vx3rgs4r	204	21	and	and	CC
cord-017142-vx3rgs4r	204	22	anemia	anemia	NN
cord-017142-vx3rgs4r	204	23	,	,	,
cord-017142-vx3rgs4r	204	24	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	204	25	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	204	26	is	be	VBZ
cord-017142-vx3rgs4r	204	27	a	a	DT
cord-017142-vx3rgs4r	204	28	possibility	possibility	NN
cord-017142-vx3rgs4r	204	29	.	.	.
cord-017142-vx3rgs4r	205	1	Diffuse	diffuse	JJ
cord-017142-vx3rgs4r	205	2	alveolar	alveolar	NN
cord-017142-vx3rgs4r	205	3	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	206	1	(	(	-LRB-
cord-017142-vx3rgs4r	206	2	DAH	DAH	NNP
cord-017142-vx3rgs4r	206	3	)	)	-RRB-
cord-017142-vx3rgs4r	206	4	has	have	VBZ
cord-017142-vx3rgs4r	206	5	been	be	VBN
cord-017142-vx3rgs4r	206	6	rarely	rarely	RB
cord-017142-vx3rgs4r	206	7	reported	report	VBN
cord-017142-vx3rgs4r	206	8	in	in	IN
cord-017142-vx3rgs4r	206	9	MM	MM	NNP
cord-017142-vx3rgs4r	206	10	patients	patient	NNS
cord-017142-vx3rgs4r	206	11	,	,	,
cord-017142-vx3rgs4r	206	12	but	but	CC
cord-017142-vx3rgs4r	206	13	there	there	EX
cord-017142-vx3rgs4r	206	14	have	have	VBP
cord-017142-vx3rgs4r	206	15	been	be	VBN
cord-017142-vx3rgs4r	206	16	cases	case	NNS
cord-017142-vx3rgs4r	206	17	associated	associate	VBN
cord-017142-vx3rgs4r	206	18	with	with	IN
cord-017142-vx3rgs4r	206	19	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	206	20	and	and	CC
cord-017142-vx3rgs4r	206	21	in	in	IN
cord-017142-vx3rgs4r	206	22	the	the	DT
cord-017142-vx3rgs4r	206	23	posttransplant	posttransplant	NN
cord-017142-vx3rgs4r	206	24	setting	set	VBG
cord-017142-vx3rgs4r	206	25	[	[	-LRB-
cord-017142-vx3rgs4r	206	26	2	2	CD
cord-017142-vx3rgs4r	206	27	,	,	,
cord-017142-vx3rgs4r	206	28	7	7	CD
cord-017142-vx3rgs4r	206	29	,	,	,
cord-017142-vx3rgs4r	206	30	8	8	CD
cord-017142-vx3rgs4r	206	31	,	,	,
cord-017142-vx3rgs4r	206	32	120	120	CD
cord-017142-vx3rgs4r	206	33	]	]	-RRB-
cord-017142-vx3rgs4r	206	34	.	.	.
cord-017142-vx3rgs4r	207	1	Though	though	IN
cord-017142-vx3rgs4r	207	2	rare	rare	JJ
cord-017142-vx3rgs4r	207	3	,	,	,
cord-017142-vx3rgs4r	207	4	this	this	DT
cord-017142-vx3rgs4r	207	5	is	be	VBZ
cord-017142-vx3rgs4r	207	6	potentially	potentially	RB
cord-017142-vx3rgs4r	207	7	a	a	DT
cord-017142-vx3rgs4r	207	8	fatal	fatal	JJ
cord-017142-vx3rgs4r	207	9	event	event	NN
cord-017142-vx3rgs4r	207	10	.	.	.
cord-017142-vx3rgs4r	208	1	A	a	DT
cord-017142-vx3rgs4r	208	2	thorough	thorough	JJ
cord-017142-vx3rgs4r	208	3	microbiology	microbiology	NN
cord-017142-vx3rgs4r	208	4	screen	screen	NN
cord-017142-vx3rgs4r	208	5	,	,	,
cord-017142-vx3rgs4r	208	6	echocardiogram	echocardiogram	NN
cord-017142-vx3rgs4r	208	7	,	,	,
cord-017142-vx3rgs4r	208	8	CT	CT	NNP
cord-017142-vx3rgs4r	208	9	imaging	imaging	NN
cord-017142-vx3rgs4r	208	10	,	,	,
cord-017142-vx3rgs4r	208	11	autoimmune	autoimmune	JJ
cord-017142-vx3rgs4r	208	12	work	work	NN
cord-017142-vx3rgs4r	208	13	-	-	HYPH
cord-017142-vx3rgs4r	208	14	up	up	NN
cord-017142-vx3rgs4r	208	15	,	,	,
cord-017142-vx3rgs4r	208	16	and	and	CC
cord-017142-vx3rgs4r	208	17	coagulopathy	coagulopathy	NN
cord-017142-vx3rgs4r	208	18	work	work	NN
cord-017142-vx3rgs4r	208	19	-	-	HYPH
cord-017142-vx3rgs4r	208	20	up	up	NN
cord-017142-vx3rgs4r	208	21	are	be	VBP
cord-017142-vx3rgs4r	208	22	warranted	warrant	VBN
cord-017142-vx3rgs4r	208	23	[	[	-LRB-
cord-017142-vx3rgs4r	208	24	115	115	CD
cord-017142-vx3rgs4r	208	25	]	]	-RRB-
cord-017142-vx3rgs4r	208	26	.	.	.
cord-017142-vx3rgs4r	209	1	BAL	BAL	NNP
cord-017142-vx3rgs4r	209	2	showing	show	VBG
cord-017142-vx3rgs4r	209	3	presence	presence	NN
cord-017142-vx3rgs4r	209	4	of	of	IN
cord-017142-vx3rgs4r	209	5	gross	gross	JJ
cord-017142-vx3rgs4r	209	6	blood	blood	NN
cord-017142-vx3rgs4r	209	7	and	and	CC
cord-017142-vx3rgs4r	209	8	the	the	DT
cord-017142-vx3rgs4r	209	9	percentage	percentage	NN
cord-017142-vx3rgs4r	209	10	of	of	IN
cord-017142-vx3rgs4r	209	11	hemosiderin	hemosiderin	NN
cord-017142-vx3rgs4r	209	12	-	-	HYPH
cord-017142-vx3rgs4r	209	13	laden	laden	JJ
cord-017142-vx3rgs4r	209	14	macrophages	macrophage	NNS
cord-017142-vx3rgs4r	209	15	(	(	-LRB-
cord-017142-vx3rgs4r	209	16	siderophages	siderophages	NNP
cord-017142-vx3rgs4r	209	17	)	)	-RRB-
cord-017142-vx3rgs4r	209	18	>	>	NFP
cord-017142-vx3rgs4r	209	19	20	20	CD
cord-017142-vx3rgs4r	209	20	%	%	NN
cord-017142-vx3rgs4r	209	21	at	at	IN
cord-017142-vx3rgs4r	209	22	BAL	BAL	NNP
cord-017142-vx3rgs4r	209	23	are	be	VBP
cord-017142-vx3rgs4r	209	24	suggestive	suggestive	JJ
cord-017142-vx3rgs4r	209	25	of	of	IN
cord-017142-vx3rgs4r	209	26	a	a	DT
cord-017142-vx3rgs4r	209	27	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	209	28	of	of	IN
cord-017142-vx3rgs4r	209	29	DAH	DAH	NNP
cord-017142-vx3rgs4r	209	30	[	[	-LRB-
cord-017142-vx3rgs4r	209	31	25	25	CD
cord-017142-vx3rgs4r	209	32	,	,	,
cord-017142-vx3rgs4r	209	33	42	42	CD
cord-017142-vx3rgs4r	209	34	,	,	,
cord-017142-vx3rgs4r	209	35	118	118	CD
cord-017142-vx3rgs4r	209	36	]	]	-RRB-
cord-017142-vx3rgs4r	209	37	.	.	.
cord-017142-vx3rgs4r	210	1	Aggressive	aggressive	JJ
cord-017142-vx3rgs4r	210	2	supportive	supportive	JJ
cord-017142-vx3rgs4r	210	3	care	care	NN
cord-017142-vx3rgs4r	210	4	and	and	CC
cord-017142-vx3rgs4r	210	5	empiric	empiric	JJ
cord-017142-vx3rgs4r	210	6	broad	broad	JJ
cord-017142-vx3rgs4r	210	7	-	-	HYPH
cord-017142-vx3rgs4r	210	8	spectrum	spectrum	NN
cord-017142-vx3rgs4r	210	9	antimicrobial	antimicrobial	NN
cord-017142-vx3rgs4r	210	10	therapy	therapy	NN
cord-017142-vx3rgs4r	210	11	should	should	MD
cord-017142-vx3rgs4r	210	12	be	be	VB
cord-017142-vx3rgs4r	210	13	considered	consider	VBN
cord-017142-vx3rgs4r	210	14	.	.	.
cord-017142-vx3rgs4r	211	1	The	the	DT
cord-017142-vx3rgs4r	211	2	role	role	NN
cord-017142-vx3rgs4r	211	3	of	of	IN
cord-017142-vx3rgs4r	211	4	early	early	JJ
cord-017142-vx3rgs4r	211	5	initiation	initiation	NN
cord-017142-vx3rgs4r	211	6	of	of	IN
cord-017142-vx3rgs4r	211	7	steroids	steroid	NNS
cord-017142-vx3rgs4r	211	8	is	be	VBZ
cord-017142-vx3rgs4r	211	9	currently	currently	RB
cord-017142-vx3rgs4r	211	10	based	base	VBN
cord-017142-vx3rgs4r	211	11	on	on	IN
cord-017142-vx3rgs4r	211	12	retrospective	retrospective	JJ
cord-017142-vx3rgs4r	211	13	series	series	NN
cord-017142-vx3rgs4r	211	14	and	and	CC
cord-017142-vx3rgs4r	211	15	case	case	NN
cord-017142-vx3rgs4r	211	16	reports	report	NNS
cord-017142-vx3rgs4r	211	17	.	.	.
cord-017142-vx3rgs4r	212	1	An	an	DT
cord-017142-vx3rgs4r	212	2	MD	MD	NNP
cord-017142-vx3rgs4r	212	3	Anderson	Anderson	NNP
cord-017142-vx3rgs4r	212	4	prospective	prospective	JJ
cord-017142-vx3rgs4r	212	5	study	study	NN
cord-017142-vx3rgs4r	212	6	examined	examine	VBD
cord-017142-vx3rgs4r	212	7	119	119	CD
cord-017142-vx3rgs4r	212	8	critically	critically	RB
cord-017142-vx3rgs4r	212	9	ill	ill	JJ
cord-017142-vx3rgs4r	212	10	adult	adult	NN
cord-017142-vx3rgs4r	212	11	hematopoietic	hematopoietic	JJ
cord-017142-vx3rgs4r	212	12	transplant	transplant	NN
cord-017142-vx3rgs4r	212	13	patients	patient	NNS
cord-017142-vx3rgs4r	212	14	treated	treat	VBN
cord-017142-vx3rgs4r	212	15	for	for	IN
cord-017142-vx3rgs4r	212	16	DAH	DAH	NNP
cord-017142-vx3rgs4r	212	17	,	,	,
cord-017142-vx3rgs4r	212	18	and	and	CC
cord-017142-vx3rgs4r	212	19	on	on	IN
cord-017142-vx3rgs4r	212	20	multivariate	multivariate	JJ
cord-017142-vx3rgs4r	212	21	analysis	analysis	NN
cord-017142-vx3rgs4r	212	22	,	,	,
cord-017142-vx3rgs4r	212	23	an	an	DT
cord-017142-vx3rgs4r	212	24	initial	initial	JJ
cord-017142-vx3rgs4r	212	25	medium	medium	NN
cord-017142-vx3rgs4r	212	26	(	(	-LRB-
cord-017142-vx3rgs4r	212	27	250	250	CD
cord-017142-vx3rgs4r	212	28	-	-	SYM
cord-017142-vx3rgs4r	212	29	1000	1000	CD
cord-017142-vx3rgs4r	212	30	mg	mg	NNP
cord-017142-vx3rgs4r	212	31	/	/	SYM
cord-017142-vx3rgs4r	212	32	day	day	NN
cord-017142-vx3rgs4r	212	33	)	)	-RRB-
cord-017142-vx3rgs4r	212	34	and	and	CC
cord-017142-vx3rgs4r	212	35	high	high	JJ
cord-017142-vx3rgs4r	212	36	-	-	HYPH
cord-017142-vx3rgs4r	212	37	dose	dose	NN
cord-017142-vx3rgs4r	212	38	(	(	-LRB-
cord-017142-vx3rgs4r	212	39	1000	1000	CD
cord-017142-vx3rgs4r	212	40	mg	mg	NNP
cord-017142-vx3rgs4r	212	41	/	/	SYM
cord-017142-vx3rgs4r	212	42	day	day	NN
cord-017142-vx3rgs4r	212	43	)	)	-RRB-
cord-017142-vx3rgs4r	212	44	steroids	steroid	NNS
cord-017142-vx3rgs4r	212	45	were	be	VBD
cord-017142-vx3rgs4r	212	46	associated	associate	VBN
cord-017142-vx3rgs4r	212	47	with	with	IN
cord-017142-vx3rgs4r	212	48	a	a	DT
cord-017142-vx3rgs4r	212	49	higher	high	JJR
cord-017142-vx3rgs4r	212	50	ICU	ICU	NNP
cord-017142-vx3rgs4r	212	51	mortality	mortality	NN
cord-017142-vx3rgs4r	212	52	(	(	-LRB-
cord-017142-vx3rgs4r	212	53	P	p	NN
cord-017142-vx3rgs4r	212	54	=	=	SYM
cord-017142-vx3rgs4r	212	55	0.01	0.01	CD
cord-017142-vx3rgs4r	212	56	)	)	-RRB-
cord-017142-vx3rgs4r	212	57	as	as	IN
cord-017142-vx3rgs4r	212	58	compared	compare	VBN
cord-017142-vx3rgs4r	212	59	with	with	IN
cord-017142-vx3rgs4r	212	60	the	the	DT
cord-017142-vx3rgs4r	212	61	low	low	JJ
cord-017142-vx3rgs4r	212	62	dose	dose	NN
cord-017142-vx3rgs4r	212	63	(	(	-LRB-
cord-017142-vx3rgs4r	212	64	<	<	NNP
cord-017142-vx3rgs4r	212	65	250	250	CD
cord-017142-vx3rgs4r	212	66	mg	mg	NNP
cord-017142-vx3rgs4r	212	67	/	/	SYM
cord-017142-vx3rgs4r	212	68	day	day	NN
cord-017142-vx3rgs4r	212	69	)	)	-RRB-
cord-017142-vx3rgs4r	212	70	.	.	.
cord-017142-vx3rgs4r	213	1	Adjunctive	Adjunctive	NNP
cord-017142-vx3rgs4r	213	2	treatment	treatment	NN
cord-017142-vx3rgs4r	213	3	with	with	IN
cord-017142-vx3rgs4r	213	4	aminocaproic	aminocaproic	NNP
cord-017142-vx3rgs4r	213	5	acid	acid	NN
cord-017142-vx3rgs4r	213	6	in	in	IN
cord-017142-vx3rgs4r	213	7	this	this	DT
cord-017142-vx3rgs4r	213	8	study	study	NN
cord-017142-vx3rgs4r	213	9	,	,	,
cord-017142-vx3rgs4r	213	10	which	which	WDT
cord-017142-vx3rgs4r	213	11	is	be	VBZ
cord-017142-vx3rgs4r	213	12	commonly	commonly	RB
cord-017142-vx3rgs4r	213	13	used	use	VBN
cord-017142-vx3rgs4r	213	14	in	in	IN
cord-017142-vx3rgs4r	213	15	DAH	DAH	NNP
cord-017142-vx3rgs4r	213	16	,	,	,
cord-017142-vx3rgs4r	213	17	did	do	VBD
cord-017142-vx3rgs4r	213	18	not	not	RB
cord-017142-vx3rgs4r	213	19	produce	produce	VB
cord-017142-vx3rgs4r	213	20	differences	difference	NNS
cord-017142-vx3rgs4r	213	21	in	in	IN
cord-017142-vx3rgs4r	213	22	outcomes	outcome	NNS
cord-017142-vx3rgs4r	213	23	[	[	-LRB-
cord-017142-vx3rgs4r	213	24	85	85	CD
cord-017142-vx3rgs4r	213	25	,	,	,
cord-017142-vx3rgs4r	213	26	105	105	CD
cord-017142-vx3rgs4r	213	27	]	]	-RRB-
cord-017142-vx3rgs4r	213	28	.	.	.
cord-017142-vx3rgs4r	214	1	Drug	drug	NN
cord-017142-vx3rgs4r	214	2	-	-	HYPH
cord-017142-vx3rgs4r	214	3	induced	induce	VBN
cord-017142-vx3rgs4r	214	4	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	214	5	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	214	6	(	(	-LRB-
cord-017142-vx3rgs4r	214	7	DIP	dip	NN
cord-017142-vx3rgs4r	214	8	)	)	-RRB-
cord-017142-vx3rgs4r	214	9	:	:	:
cord-017142-vx3rgs4r	215	1	DIP	dip	VB
cord-017142-vx3rgs4r	215	2	manifesting	manifest	VBG
cord-017142-vx3rgs4r	215	3	as	as	IN
cord-017142-vx3rgs4r	215	4	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	215	5	lung	lung	NN
cord-017142-vx3rgs4r	215	6	disease	disease	NN
cord-017142-vx3rgs4r	215	7	has	have	VBZ
cord-017142-vx3rgs4r	215	8	been	be	VBN
cord-017142-vx3rgs4r	215	9	reported	report	VBN
cord-017142-vx3rgs4r	215	10	with	with	IN
cord-017142-vx3rgs4r	215	11	lenalidomide	lenalidomide	NN
cord-017142-vx3rgs4r	215	12	,	,	,
cord-017142-vx3rgs4r	215	13	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	215	14	,	,	,
cord-017142-vx3rgs4r	215	15	and	and	CC
cord-017142-vx3rgs4r	215	16	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	215	17	[	[	-LRB-
cord-017142-vx3rgs4r	215	18	16	16	CD
cord-017142-vx3rgs4r	215	19	,	,	,
cord-017142-vx3rgs4r	215	20	20	20	CD
cord-017142-vx3rgs4r	215	21	,	,	,
cord-017142-vx3rgs4r	215	22	113	113	CD
cord-017142-vx3rgs4r	215	23	,	,	,
cord-017142-vx3rgs4r	215	24	123	123	CD
cord-017142-vx3rgs4r	215	25	]	]	-RRB-
cord-017142-vx3rgs4r	215	26	.	.	.
cord-017142-vx3rgs4r	216	1	Though	though	IN
cord-017142-vx3rgs4r	216	2	mechanisms	mechanism	NNS
cord-017142-vx3rgs4r	216	3	are	be	VBP
cord-017142-vx3rgs4r	216	4	not	not	RB
cord-017142-vx3rgs4r	216	5	fully	fully	RB
cord-017142-vx3rgs4r	216	6	elucidated	elucidate	VBN
cord-017142-vx3rgs4r	216	7	,	,	,
cord-017142-vx3rgs4r	216	8	oxidative	oxidative	JJ
cord-017142-vx3rgs4r	216	9	stress	stress	NN
cord-017142-vx3rgs4r	216	10	,	,	,
cord-017142-vx3rgs4r	216	11	prostaglandin	prostaglandin	NN
cord-017142-vx3rgs4r	216	12	E2	e2	NN
cord-017142-vx3rgs4r	216	13	(	(	-LRB-
cord-017142-vx3rgs4r	216	14	PGE2	PGE2	NNP
cord-017142-vx3rgs4r	216	15	)	)	-RRB-
cord-017142-vx3rgs4r	216	16	inhibition	inhibition	NN
cord-017142-vx3rgs4r	216	17	,	,	,
cord-017142-vx3rgs4r	216	18	fibroblast	fibroblast	NN
cord-017142-vx3rgs4r	216	19	proliferation	proliferation	NN
cord-017142-vx3rgs4r	216	20	,	,	,
cord-017142-vx3rgs4r	216	21	and	and	CC
cord-017142-vx3rgs4r	216	22	impairment	impairment	NN
cord-017142-vx3rgs4r	216	23	of	of	IN
cord-017142-vx3rgs4r	216	24	cell	cell	NN
cord-017142-vx3rgs4r	216	25	repair	repair	NN
cord-017142-vx3rgs4r	216	26	by	by	IN
cord-017142-vx3rgs4r	216	27	epidermal	epidermal	JJ
cord-017142-vx3rgs4r	216	28	growth	growth	NN
cord-017142-vx3rgs4r	216	29	factor	factor	NN
cord-017142-vx3rgs4r	216	30	receptor	receptor	NN
cord-017142-vx3rgs4r	216	31	blocking	blocking	NN
cord-017142-vx3rgs4r	216	32	may	may	MD
cord-017142-vx3rgs4r	216	33	play	play	VB
cord-017142-vx3rgs4r	216	34	a	a	DT
cord-017142-vx3rgs4r	216	35	role	role	NN
cord-017142-vx3rgs4r	216	36	.	.	.
cord-017142-vx3rgs4r	217	1	BAL	bal	NN
cord-017142-vx3rgs4r	217	2	with	with	IN
cord-017142-vx3rgs4r	217	3	culture	culture	NN
cord-017142-vx3rgs4r	217	4	and	and	CC
cord-017142-vx3rgs4r	217	5	microscopy	microscopy	NN
cord-017142-vx3rgs4r	217	6	should	should	MD
cord-017142-vx3rgs4r	217	7	be	be	VB
cord-017142-vx3rgs4r	217	8	able	able	JJ
cord-017142-vx3rgs4r	217	9	to	to	TO
cord-017142-vx3rgs4r	217	10	help	help	VB
cord-017142-vx3rgs4r	217	11	rule	rule	VB
cord-017142-vx3rgs4r	217	12	out	out	RP
cord-017142-vx3rgs4r	217	13	infectious	infectious	JJ
cord-017142-vx3rgs4r	217	14	causes	cause	NNS
cord-017142-vx3rgs4r	217	15	.	.	.
cord-017142-vx3rgs4r	218	1	The	the	DT
cord-017142-vx3rgs4r	218	2	lymphocytic	lymphocytic	JJ
cord-017142-vx3rgs4r	218	3	preponderance	preponderance	NN
cord-017142-vx3rgs4r	218	4	typically	typically	RB
cord-017142-vx3rgs4r	218	5	seen	see	VBN
cord-017142-vx3rgs4r	218	6	in	in	IN
cord-017142-vx3rgs4r	218	7	bronchoalveolar	bronchoalveolar	NNP
cord-017142-vx3rgs4r	218	8	lavage	lavage	NNP
cord-017142-vx3rgs4r	218	9	(	(	-LRB-
cord-017142-vx3rgs4r	218	10	BAL	BAL	NNP
cord-017142-vx3rgs4r	218	11	)	)	-RRB-
cord-017142-vx3rgs4r	218	12	is	be	VBZ
cord-017142-vx3rgs4r	218	13	supportive	supportive	JJ
cord-017142-vx3rgs4r	218	14	of	of	IN
cord-017142-vx3rgs4r	218	15	a	a	DT
cord-017142-vx3rgs4r	218	16	hypersensitivity	hypersensitivity	NN
cord-017142-vx3rgs4r	218	17	mechanism	mechanism	NN
cord-017142-vx3rgs4r	218	18	;	;	:
cord-017142-vx3rgs4r	218	19	however	however	RB
cord-017142-vx3rgs4r	218	20	,	,	,
cord-017142-vx3rgs4r	218	21	this	this	DT
cord-017142-vx3rgs4r	218	22	finding	finding	NN
cord-017142-vx3rgs4r	218	23	is	be	VBZ
cord-017142-vx3rgs4r	218	24	nondiagnostic	nondiagnostic	JJ
cord-017142-vx3rgs4r	218	25	and	and	CC
cord-017142-vx3rgs4r	218	26	requires	require	VBZ
cord-017142-vx3rgs4r	218	27	meticulous	meticulous	JJ
cord-017142-vx3rgs4r	218	28	exclusion	exclusion	NN
cord-017142-vx3rgs4r	218	29	of	of	IN
cord-017142-vx3rgs4r	218	30	other	other	JJ
cord-017142-vx3rgs4r	218	31	causes	cause	NNS
cord-017142-vx3rgs4r	218	32	.	.	.
cord-017142-vx3rgs4r	219	1	Invasive	invasive	JJ
cord-017142-vx3rgs4r	219	2	procedures	procedure	NNS
cord-017142-vx3rgs4r	219	3	like	like	IN
cord-017142-vx3rgs4r	219	4	biopsy	biopsy	NN
cord-017142-vx3rgs4r	219	5	usually	usually	RB
cord-017142-vx3rgs4r	219	6	do	do	VBP
cord-017142-vx3rgs4r	219	7	not	not	RB
cord-017142-vx3rgs4r	219	8	provide	provide	VB
cord-017142-vx3rgs4r	219	9	any	any	DT
cord-017142-vx3rgs4r	219	10	specific	specific	JJ
cord-017142-vx3rgs4r	219	11	findings	finding	NNS
cord-017142-vx3rgs4r	219	12	diagnostic	diagnostic	JJ
cord-017142-vx3rgs4r	219	13	for	for	IN
cord-017142-vx3rgs4r	219	14	DIP	dip	NN
cord-017142-vx3rgs4r	219	15	and	and	CC
cord-017142-vx3rgs4r	219	16	,	,	,
cord-017142-vx3rgs4r	219	17	therefore	therefore	RB
cord-017142-vx3rgs4r	219	18	,	,	,
cord-017142-vx3rgs4r	219	19	should	should	MD
cord-017142-vx3rgs4r	219	20	be	be	VB
cord-017142-vx3rgs4r	219	21	obtained	obtain	VBN
cord-017142-vx3rgs4r	219	22	only	only	RB
cord-017142-vx3rgs4r	219	23	on	on	IN
cord-017142-vx3rgs4r	219	24	a	a	DT
cord-017142-vx3rgs4r	219	25	case	case	NN
cord-017142-vx3rgs4r	219	26	-	-	HYPH
cord-017142-vx3rgs4r	219	27	by	by	IN
cord-017142-vx3rgs4r	219	28	-	-	HYPH
cord-017142-vx3rgs4r	219	29	case	case	NN
cord-017142-vx3rgs4r	219	30	basis	basis	NN
cord-017142-vx3rgs4r	219	31	.	.	.
cord-017142-vx3rgs4r	220	1	Once	once	IN
cord-017142-vx3rgs4r	220	2	DIP	dip	NN
cord-017142-vx3rgs4r	220	3	is	be	VBZ
cord-017142-vx3rgs4r	220	4	suspected	suspect	VBN
cord-017142-vx3rgs4r	220	5	,	,	,
cord-017142-vx3rgs4r	220	6	stopping	stop	VBG
cord-017142-vx3rgs4r	220	7	the	the	DT
cord-017142-vx3rgs4r	220	8	offending	offending	JJ
cord-017142-vx3rgs4r	220	9	agent	agent	NN
cord-017142-vx3rgs4r	220	10	is	be	VBZ
cord-017142-vx3rgs4r	220	11	the	the	DT
cord-017142-vx3rgs4r	220	12	main	main	JJ
cord-017142-vx3rgs4r	220	13	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	220	14	approach	approach	NN
cord-017142-vx3rgs4r	220	15	;	;	:
cord-017142-vx3rgs4r	220	16	steroids	steroid	NNS
cord-017142-vx3rgs4r	220	17	may	may	MD
cord-017142-vx3rgs4r	220	18	be	be	VB
cord-017142-vx3rgs4r	220	19	used	use	VBN
cord-017142-vx3rgs4r	220	20	in	in	IN
cord-017142-vx3rgs4r	220	21	severe	severe	JJ
cord-017142-vx3rgs4r	220	22	cases	case	NNS
cord-017142-vx3rgs4r	220	23	[	[	-LRB-
cord-017142-vx3rgs4r	220	24	4	4	CD
cord-017142-vx3rgs4r	220	25	,	,	,
cord-017142-vx3rgs4r	220	26	61	61	CD
cord-017142-vx3rgs4r	220	27	]	]	-RRB-
cord-017142-vx3rgs4r	220	28	.	.	.
cord-017142-vx3rgs4r	221	1	Although	although	IN
cord-017142-vx3rgs4r	221	2	no	no	DT
cord-017142-vx3rgs4r	221	3	guidelines	guideline	NNS
cord-017142-vx3rgs4r	221	4	exist	exist	VBP
cord-017142-vx3rgs4r	221	5	on	on	IN
cord-017142-vx3rgs4r	221	6	the	the	DT
cord-017142-vx3rgs4r	221	7	duration	duration	NN
cord-017142-vx3rgs4r	221	8	of	of	IN
cord-017142-vx3rgs4r	221	9	steroids	steroid	NNS
cord-017142-vx3rgs4r	221	10	,	,	,
cord-017142-vx3rgs4r	221	11	in	in	IN
cord-017142-vx3rgs4r	221	12	general	general	JJ
cord-017142-vx3rgs4r	221	13	,	,	,
cord-017142-vx3rgs4r	221	14	a	a	DT
cord-017142-vx3rgs4r	221	15	slow	slow	JJ
cord-017142-vx3rgs4r	221	16	taper	taper	NN
cord-017142-vx3rgs4r	221	17	is	be	VBZ
cord-017142-vx3rgs4r	221	18	recommended	recommend	VBN
cord-017142-vx3rgs4r	221	19	[	[	-LRB-
cord-017142-vx3rgs4r	221	20	61	61	CD
cord-017142-vx3rgs4r	221	21	]	]	-RRB-
cord-017142-vx3rgs4r	221	22	.	.	.
cord-017142-vx3rgs4r	222	1	Caution	caution	NN
cord-017142-vx3rgs4r	222	2	should	should	MD
cord-017142-vx3rgs4r	222	3	be	be	VB
cord-017142-vx3rgs4r	222	4	maintained	maintain	VBN
cord-017142-vx3rgs4r	222	5	on	on	IN
cord-017142-vx3rgs4r	222	6	rechallenging	rechallenge	VBG
cord-017142-vx3rgs4r	222	7	the	the	DT
cord-017142-vx3rgs4r	222	8	patients	patient	NNS
cord-017142-vx3rgs4r	222	9	with	with	IN
cord-017142-vx3rgs4r	222	10	the	the	DT
cord-017142-vx3rgs4r	222	11	offending	offending	JJ
cord-017142-vx3rgs4r	222	12	medication	medication	NN
cord-017142-vx3rgs4r	222	13	as	as	IN
cord-017142-vx3rgs4r	222	14	the	the	DT
cord-017142-vx3rgs4r	222	15	risk	risk	NN
cord-017142-vx3rgs4r	222	16	of	of	IN
cord-017142-vx3rgs4r	222	17	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	222	18	reaction	reaction	NN
cord-017142-vx3rgs4r	222	19	is	be	VBZ
cord-017142-vx3rgs4r	222	20	extremely	extremely	RB
cord-017142-vx3rgs4r	222	21	high	high	JJ
cord-017142-vx3rgs4r	222	22	.	.	.
cord-017142-vx3rgs4r	223	1	Hypercalcemia	Hypercalcemia	NNP
cord-017142-vx3rgs4r	223	2	:	:	:
cord-017142-vx3rgs4r	224	1	Being	be	VBG
cord-017142-vx3rgs4r	224	2	one	one	CD
cord-017142-vx3rgs4r	224	3	of	of	IN
cord-017142-vx3rgs4r	224	4	the	the	DT
cord-017142-vx3rgs4r	224	5	four	four	CD
cord-017142-vx3rgs4r	224	6	diagnostic	diagnostic	JJ
cord-017142-vx3rgs4r	224	7	criteria	criterion	NNS
cord-017142-vx3rgs4r	224	8	for	for	IN
cord-017142-vx3rgs4r	224	9	MM	MM	NNP
cord-017142-vx3rgs4r	225	1	(	(	-LRB-
cord-017142-vx3rgs4r	225	2	CRAB	CRAB	NNP
cord-017142-vx3rgs4r	225	3	criteriacalcium	criteriacalcium	NNP
cord-017142-vx3rgs4r	225	4	,	,	,
cord-017142-vx3rgs4r	225	5	renal	renal	JJ
cord-017142-vx3rgs4r	225	6	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	225	7	,	,	,
cord-017142-vx3rgs4r	225	8	anemia	anemia	NN
cord-017142-vx3rgs4r	225	9	,	,	,
cord-017142-vx3rgs4r	225	10	and	and	CC
cord-017142-vx3rgs4r	225	11	bone	bone	NN
cord-017142-vx3rgs4r	225	12	disease	disease	NN
cord-017142-vx3rgs4r	225	13	)	)	-RRB-
cord-017142-vx3rgs4r	225	14	,	,	,
cord-017142-vx3rgs4r	225	15	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	225	16	is	be	VBZ
cord-017142-vx3rgs4r	225	17	defined	define	VBN
cord-017142-vx3rgs4r	225	18	as	as	IN
cord-017142-vx3rgs4r	225	19	calcium	calcium	NN
cord-017142-vx3rgs4r	225	20	level	level	NN
cord-017142-vx3rgs4r	225	21	corrected	correct	VBN
cord-017142-vx3rgs4r	225	22	for	for	IN
cord-017142-vx3rgs4r	225	23	albumin	albumin	NN
cord-017142-vx3rgs4r	225	24	11	11	CD
cord-017142-vx3rgs4r	225	25	mg	mg	NNP
cord-017142-vx3rgs4r	225	26	/	/	SYM
cord-017142-vx3rgs4r	225	27	dL.	dL.	NNS
cord-017142-vx3rgs4r	226	1	Almost	almost	RB
cord-017142-vx3rgs4r	226	2	a	a	DT
cord-017142-vx3rgs4r	226	3	third	third	NN
cord-017142-vx3rgs4r	226	4	of	of	IN
cord-017142-vx3rgs4r	226	5	MM	MM	NNP
cord-017142-vx3rgs4r	226	6	patients	patient	NNS
cord-017142-vx3rgs4r	226	7	are	be	VBP
cord-017142-vx3rgs4r	226	8	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	226	9	with	with	IN
cord-017142-vx3rgs4r	226	10	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	226	11	at	at	IN
cord-017142-vx3rgs4r	226	12	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	226	13	or	or	CC
cord-017142-vx3rgs4r	226	14	during	during	IN
cord-017142-vx3rgs4r	226	15	the	the	DT
cord-017142-vx3rgs4r	226	16	disease	disease	NN
cord-017142-vx3rgs4r	226	17	course	course	NN
cord-017142-vx3rgs4r	226	18	[	[	-LRB-
cord-017142-vx3rgs4r	226	19	64	64	CD
cord-017142-vx3rgs4r	226	20	,	,	,
cord-017142-vx3rgs4r	226	21	141	141	CD
cord-017142-vx3rgs4r	226	22	]	]	-RRB-
cord-017142-vx3rgs4r	226	23	.	.	.
cord-017142-vx3rgs4r	227	1	The	the	DT
cord-017142-vx3rgs4r	227	2	mechanism	mechanism	NN
cord-017142-vx3rgs4r	227	3	is	be	VBZ
cord-017142-vx3rgs4r	227	4	due	due	JJ
cord-017142-vx3rgs4r	227	5	to	to	IN
cord-017142-vx3rgs4r	227	6	local	local	JJ
cord-017142-vx3rgs4r	227	7	osteolysis	osteolysis	NN
cord-017142-vx3rgs4r	227	8	;	;	:
cord-017142-vx3rgs4r	227	9	at	at	IN
cord-017142-vx3rgs4r	227	10	the	the	DT
cord-017142-vx3rgs4r	227	11	cellular	cellular	JJ
cord-017142-vx3rgs4r	227	12	level	level	NN
cord-017142-vx3rgs4r	227	13	,	,	,
cord-017142-vx3rgs4r	227	14	it	-PRON-	PRP
cord-017142-vx3rgs4r	227	15	is	be	VBZ
cord-017142-vx3rgs4r	227	16	mediated	mediate	VBN
cord-017142-vx3rgs4r	227	17	by	by	IN
cord-017142-vx3rgs4r	227	18	interleukin	interleukin	NN
cord-017142-vx3rgs4r	227	19	1	1	CD
cord-017142-vx3rgs4r	227	20	,	,	,
cord-017142-vx3rgs4r	227	21	interleukin	interleukin	NN
cord-017142-vx3rgs4r	227	22	6	6	CD
cord-017142-vx3rgs4r	227	23	,	,	,
cord-017142-vx3rgs4r	227	24	and	and	CC
cord-017142-vx3rgs4r	227	25	tumor	tumor	NN
cord-017142-vx3rgs4r	227	26	necrosis	necrosis	NN
cord-017142-vx3rgs4r	227	27	factor	factor	NN
cord-017142-vx3rgs4r	227	28	α	α	NN
cord-017142-vx3rgs4r	227	29	with	with	IN
cord-017142-vx3rgs4r	227	30	RANKL	RANKL	NNP
cord-017142-vx3rgs4r	227	31	being	be	VBG
cord-017142-vx3rgs4r	227	32	the	the	DT
cord-017142-vx3rgs4r	227	33	final	final	JJ
cord-017142-vx3rgs4r	227	34	common	common	JJ
cord-017142-vx3rgs4r	227	35	mediator	mediator	NN
cord-017142-vx3rgs4r	227	36	.	.	.
cord-017142-vx3rgs4r	228	1	Most	Most	JJS
cord-017142-vx3rgs4r	228	2	patients	patient	NNS
cord-017142-vx3rgs4r	228	3	presenting	present	VBG
cord-017142-vx3rgs4r	228	4	with	with	IN
cord-017142-vx3rgs4r	228	5	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	228	6	have	have	VBP
cord-017142-vx3rgs4r	228	7	associated	associate	VBN
cord-017142-vx3rgs4r	228	8	anemia	anemia	NN
cord-017142-vx3rgs4r	228	9	,	,	,
cord-017142-vx3rgs4r	228	10	thrombocytopenia	thrombocytopenia	NN
cord-017142-vx3rgs4r	228	11	,	,	,
cord-017142-vx3rgs4r	228	12	kidney	kidney	NN
cord-017142-vx3rgs4r	228	13	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	228	14	,	,	,
cord-017142-vx3rgs4r	228	15	lytic	lytic	JJ
cord-017142-vx3rgs4r	228	16	lesions	lesion	NNS
cord-017142-vx3rgs4r	228	17	,	,	,
cord-017142-vx3rgs4r	228	18	and	and	CC
cord-017142-vx3rgs4r	228	19	advancedstage	advancedstage	NN
cord-017142-vx3rgs4r	228	20	disease	disease	NN
cord-017142-vx3rgs4r	228	21	.	.	.
cord-017142-vx3rgs4r	229	1	Hypercalcemia	Hypercalcemia	NNP
cord-017142-vx3rgs4r	229	2	is	be	VBZ
cord-017142-vx3rgs4r	229	3	associated	associate	VBN
cord-017142-vx3rgs4r	229	4	with	with	IN
cord-017142-vx3rgs4r	229	5	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	229	6	disease	disease	NN
cord-017142-vx3rgs4r	229	7	biology	biology	NN
cord-017142-vx3rgs4r	229	8	and	and	CC
cord-017142-vx3rgs4r	229	9	heavy	heavy	JJ
cord-017142-vx3rgs4r	229	10	disease	disease	NN
cord-017142-vx3rgs4r	229	11	burden	burden	NN
cord-017142-vx3rgs4r	229	12	and	and	CC
cord-017142-vx3rgs4r	229	13	remains	remain	VBZ
cord-017142-vx3rgs4r	229	14	a	a	DT
cord-017142-vx3rgs4r	229	15	poor	poor	JJ
cord-017142-vx3rgs4r	229	16	prognostic	prognostic	JJ
cord-017142-vx3rgs4r	229	17	feature	feature	NN
cord-017142-vx3rgs4r	229	18	even	even	RB
cord-017142-vx3rgs4r	229	19	in	in	IN
cord-017142-vx3rgs4r	229	20	the	the	DT
cord-017142-vx3rgs4r	229	21	era	era	NN
cord-017142-vx3rgs4r	229	22	of	of	IN
cord-017142-vx3rgs4r	229	23	novel	novel	JJ
cord-017142-vx3rgs4r	229	24	agents	agent	NNS
cord-017142-vx3rgs4r	229	25	[	[	-LRB-
cord-017142-vx3rgs4r	229	26	141	141	CD
cord-017142-vx3rgs4r	229	27	]	]	-RRB-
cord-017142-vx3rgs4r	229	28	.	.	.
cord-017142-vx3rgs4r	230	1	Clinically	clinically	RB
cord-017142-vx3rgs4r	230	2	,	,	,
cord-017142-vx3rgs4r	230	3	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	230	4	can	can	MD
cord-017142-vx3rgs4r	230	5	be	be	VB
cord-017142-vx3rgs4r	230	6	asymptomatic	asymptomatic	JJ
cord-017142-vx3rgs4r	230	7	;	;	:
cord-017142-vx3rgs4r	230	8	however	however	RB
cord-017142-vx3rgs4r	230	9	,	,	,
cord-017142-vx3rgs4r	230	10	patients	patient	NNS
cord-017142-vx3rgs4r	230	11	often	often	RB
cord-017142-vx3rgs4r	230	12	have	have	VBP
cord-017142-vx3rgs4r	230	13	symptoms	symptom	NNS
cord-017142-vx3rgs4r	230	14	which	which	WDT
cord-017142-vx3rgs4r	230	15	range	range	VBP
cord-017142-vx3rgs4r	230	16	from	from	IN
cord-017142-vx3rgs4r	230	17	subtle	subtle	JJ
cord-017142-vx3rgs4r	230	18	signs	sign	NNS
cord-017142-vx3rgs4r	230	19	of	of	IN
cord-017142-vx3rgs4r	230	20	malaise	malaise	NN
cord-017142-vx3rgs4r	230	21	or	or	CC
cord-017142-vx3rgs4r	230	22	fatigue	fatigue	NN
cord-017142-vx3rgs4r	230	23	to	to	IN
cord-017142-vx3rgs4r	230	24	severe	severe	JJ
cord-017142-vx3rgs4r	230	25	consequences	consequence	NNS
cord-017142-vx3rgs4r	230	26	including	include	VBG
cord-017142-vx3rgs4r	230	27	renal	renal	JJ
cord-017142-vx3rgs4r	230	28	failure	failure	NN
cord-017142-vx3rgs4r	230	29	,	,	,
cord-017142-vx3rgs4r	230	30	altered	alter	VBN
cord-017142-vx3rgs4r	230	31	mentation	mentation	NN
cord-017142-vx3rgs4r	230	32	,	,	,
cord-017142-vx3rgs4r	230	33	seizures	seizure	NNS
cord-017142-vx3rgs4r	230	34	,	,	,
cord-017142-vx3rgs4r	230	35	shortened	shorten	VBN
cord-017142-vx3rgs4r	230	36	QT	qt	NN
cord-017142-vx3rgs4r	230	37	,	,	,
cord-017142-vx3rgs4r	230	38	and	and	CC
cord-017142-vx3rgs4r	230	39	risk	risk	NN
cord-017142-vx3rgs4r	230	40	of	of	IN
cord-017142-vx3rgs4r	230	41	arrhythmias	arrhythmia	NNS
cord-017142-vx3rgs4r	230	42	.	.	.
cord-017142-vx3rgs4r	231	1	Gastrointestinal	gastrointestinal	JJ
cord-017142-vx3rgs4r	231	2	manifestations	manifestation	NNS
cord-017142-vx3rgs4r	231	3	such	such	JJ
cord-017142-vx3rgs4r	231	4	as	as	IN
cord-017142-vx3rgs4r	231	5	nausea	nausea	NN
cord-017142-vx3rgs4r	231	6	,	,	,
cord-017142-vx3rgs4r	231	7	vomiting	vomiting	NN
cord-017142-vx3rgs4r	231	8	,	,	,
cord-017142-vx3rgs4r	231	9	ileus	ileus	NN
cord-017142-vx3rgs4r	231	10	,	,	,
cord-017142-vx3rgs4r	231	11	anorexia	anorexia	NN
cord-017142-vx3rgs4r	231	12	,	,	,
cord-017142-vx3rgs4r	231	13	and	and	CC
cord-017142-vx3rgs4r	231	14	episodes	episode	NNS
cord-017142-vx3rgs4r	231	15	of	of	IN
cord-017142-vx3rgs4r	231	16	pancreatitis	pancreatitis	NN
cord-017142-vx3rgs4r	231	17	have	have	VBP
cord-017142-vx3rgs4r	231	18	been	be	VBN
cord-017142-vx3rgs4r	231	19	reported	report	VBN
cord-017142-vx3rgs4r	231	20	[	[	-LRB-
cord-017142-vx3rgs4r	231	21	82	82	CD
cord-017142-vx3rgs4r	231	22	]	]	-RRB-
cord-017142-vx3rgs4r	231	23	.	.	.
cord-017142-vx3rgs4r	232	1	If	if	IN
cord-017142-vx3rgs4r	232	2	not	not	RB
cord-017142-vx3rgs4r	232	3	treated	treat	VBN
cord-017142-vx3rgs4r	232	4	promptly	promptly	RB
cord-017142-vx3rgs4r	232	5	,	,	,
cord-017142-vx3rgs4r	232	6	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	232	7	is	be	VBZ
cord-017142-vx3rgs4r	232	8	lethal	lethal	JJ
cord-017142-vx3rgs4r	232	9	.	.	.
cord-017142-vx3rgs4r	233	1	Increased	increase	VBN
cord-017142-vx3rgs4r	233	2	calcium	calcium	NN
cord-017142-vx3rgs4r	233	3	promotes	promote	VBZ
cord-017142-vx3rgs4r	233	4	natriuresis	natriuresis	NNP
cord-017142-vx3rgs4r	233	5	which	which	WDT
cord-017142-vx3rgs4r	233	6	can	can	MD
cord-017142-vx3rgs4r	233	7	further	further	RB
cord-017142-vx3rgs4r	233	8	worsen	worsen	VB
cord-017142-vx3rgs4r	233	9	an	an	DT
cord-017142-vx3rgs4r	233	10	already	already	RB
cord-017142-vx3rgs4r	233	11	compromised	compromise	VBN
cord-017142-vx3rgs4r	233	12	kidney	kidney	NN
cord-017142-vx3rgs4r	233	13	function	function	NN
cord-017142-vx3rgs4r	233	14	.	.	.
cord-017142-vx3rgs4r	234	1	This	this	DT
cord-017142-vx3rgs4r	234	2	dehydration	dehydration	NN
cord-017142-vx3rgs4r	234	3	then	then	RB
cord-017142-vx3rgs4r	234	4	leads	lead	VBZ
cord-017142-vx3rgs4r	234	5	to	to	IN
cord-017142-vx3rgs4r	234	6	worsening	worsen	VBG
cord-017142-vx3rgs4r	234	7	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	234	8	and	and	CC
cord-017142-vx3rgs4r	234	9	renal	renal	JJ
cord-017142-vx3rgs4r	234	10	function	function	NN
cord-017142-vx3rgs4r	234	11	.	.	.
cord-017142-vx3rgs4r	235	1	Though	though	IN
cord-017142-vx3rgs4r	235	2	the	the	DT
cord-017142-vx3rgs4r	235	3	threshold	threshold	NN
cord-017142-vx3rgs4r	235	4	levels	level	NNS
cord-017142-vx3rgs4r	235	5	are	be	VBP
cord-017142-vx3rgs4r	235	6	arbitrary	arbitrary	JJ
cord-017142-vx3rgs4r	235	7	,	,	,
cord-017142-vx3rgs4r	235	8	patients	patient	NNS
cord-017142-vx3rgs4r	235	9	with	with	IN
cord-017142-vx3rgs4r	235	10	serum	serum	NN
cord-017142-vx3rgs4r	235	11	calcium	calcium	NN
cord-017142-vx3rgs4r	235	12	level	level	NN
cord-017142-vx3rgs4r	235	13	<	<	XX
cord-017142-vx3rgs4r	236	1	12	12	CD
cord-017142-vx3rgs4r	236	2	mg	mg	NNP
cord-017142-vx3rgs4r	236	3	/	/	SYM
cord-017142-vx3rgs4r	236	4	dL	dl	NN
cord-017142-vx3rgs4r	236	5	or	or	CC
cord-017142-vx3rgs4r	236	6	minimal	minimal	JJ
cord-017142-vx3rgs4r	236	7	symptoms	symptom	NNS
cord-017142-vx3rgs4r	236	8	can	can	MD
cord-017142-vx3rgs4r	236	9	be	be	VB
cord-017142-vx3rgs4r	236	10	managed	manage	VBN
cord-017142-vx3rgs4r	236	11	with	with	IN
cord-017142-vx3rgs4r	236	12	fluid	fluid	JJ
cord-017142-vx3rgs4r	236	13	resuscitation	resuscitation	NN
cord-017142-vx3rgs4r	236	14	which	which	WDT
cord-017142-vx3rgs4r	236	15	reverses	reverse	VBZ
cord-017142-vx3rgs4r	236	16	the	the	DT
cord-017142-vx3rgs4r	236	17	hypovolemia	hypovolemia	NN
cord-017142-vx3rgs4r	236	18	,	,	,
cord-017142-vx3rgs4r	236	19	repletes	replete	VBZ
cord-017142-vx3rgs4r	236	20	the	the	DT
cord-017142-vx3rgs4r	236	21	intravascular	intravascular	JJ
cord-017142-vx3rgs4r	236	22	volume	volume	NN
cord-017142-vx3rgs4r	236	23	deficit	deficit	NN
cord-017142-vx3rgs4r	236	24	,	,	,
cord-017142-vx3rgs4r	236	25	and	and	CC
cord-017142-vx3rgs4r	236	26	improves	improve	VBZ
cord-017142-vx3rgs4r	236	27	urinary	urinary	JJ
cord-017142-vx3rgs4r	236	28	calcium	calcium	NN
cord-017142-vx3rgs4r	236	29	excretion	excretion	NN
cord-017142-vx3rgs4r	236	30	.	.	.
cord-017142-vx3rgs4r	237	1	Though	though	IN
cord-017142-vx3rgs4r	237	2	the	the	DT
cord-017142-vx3rgs4r	237	3	definitive	definitive	JJ
cord-017142-vx3rgs4r	237	4	approach	approach	NN
cord-017142-vx3rgs4r	237	5	is	be	VBZ
cord-017142-vx3rgs4r	237	6	prompt	prompt	JJ
cord-017142-vx3rgs4r	237	7	MM	MM	NNP
cord-017142-vx3rgs4r	237	8	treatment	treatment	NN
cord-017142-vx3rgs4r	237	9	initiation	initiation	NN
cord-017142-vx3rgs4r	237	10	,	,	,
cord-017142-vx3rgs4r	237	11	often	often	RB
cord-017142-vx3rgs4r	237	12	due	due	JJ
cord-017142-vx3rgs4r	237	13	to	to	IN
cord-017142-vx3rgs4r	237	14	patient	patient	JJ
cord-017142-vx3rgs4r	237	15	frailty	frailty	NN
cord-017142-vx3rgs4r	237	16	and	and	CC
cord-017142-vx3rgs4r	237	17	concomitant	concomitant	JJ
cord-017142-vx3rgs4r	237	18	organ	organ	NN
cord-017142-vx3rgs4r	237	19	damage	damage	NN
cord-017142-vx3rgs4r	237	20	,	,	,
cord-017142-vx3rgs4r	237	21	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	237	22	can	can	MD
cord-017142-vx3rgs4r	237	23	not	not	RB
cord-017142-vx3rgs4r	237	24	be	be	VB
cord-017142-vx3rgs4r	237	25	initiated	initiate	VBN
cord-017142-vx3rgs4r	237	26	until	until	IN
cord-017142-vx3rgs4r	237	27	the	the	DT
cord-017142-vx3rgs4r	237	28	patient	patient	NN
cord-017142-vx3rgs4r	237	29	is	be	VBZ
cord-017142-vx3rgs4r	237	30	more	more	RBR
cord-017142-vx3rgs4r	237	31	stable	stable	JJ
cord-017142-vx3rgs4r	237	32	.	.	.
cord-017142-vx3rgs4r	238	1	If	if	IN
cord-017142-vx3rgs4r	238	2	the	the	DT
cord-017142-vx3rgs4r	238	3	patient	patient	NN
cord-017142-vx3rgs4r	238	4	is	be	VBZ
cord-017142-vx3rgs4r	238	5	on	on	IN
cord-017142-vx3rgs4r	238	6	calcium	calcium	NN
cord-017142-vx3rgs4r	238	7	,	,	,
cord-017142-vx3rgs4r	238	8	vitamin	vitamin	NN
cord-017142-vx3rgs4r	238	9	D	d	NN
cord-017142-vx3rgs4r	238	10	supplements	supplement	NNS
cord-017142-vx3rgs4r	238	11	,	,	,
cord-017142-vx3rgs4r	238	12	thiazide	thiazide	NN
cord-017142-vx3rgs4r	238	13	diuretics	diuretic	NNS
cord-017142-vx3rgs4r	238	14	,	,	,
cord-017142-vx3rgs4r	238	15	or	or	CC
cord-017142-vx3rgs4r	238	16	any	any	DT
cord-017142-vx3rgs4r	238	17	other	other	JJ
cord-017142-vx3rgs4r	238	18	drugs	drug	NNS
cord-017142-vx3rgs4r	238	19	which	which	WDT
cord-017142-vx3rgs4r	238	20	promote	promote	VBP
cord-017142-vx3rgs4r	238	21	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	238	22	,	,	,
cord-017142-vx3rgs4r	238	23	they	-PRON-	PRP
cord-017142-vx3rgs4r	238	24	should	should	MD
cord-017142-vx3rgs4r	238	25	be	be	VB
cord-017142-vx3rgs4r	238	26	stopped	stop	VBN
cord-017142-vx3rgs4r	238	27	immediately	immediately	RB
cord-017142-vx3rgs4r	238	28	.	.	.
cord-017142-vx3rgs4r	239	1	In	in	IN
cord-017142-vx3rgs4r	239	2	patients	patient	NNS
cord-017142-vx3rgs4r	239	3	with	with	IN
cord-017142-vx3rgs4r	239	4	levels	level	NNS
cord-017142-vx3rgs4r	239	5	>	>	XX
cord-017142-vx3rgs4r	240	1	14	14	CD
cord-017142-vx3rgs4r	240	2	mg	mg	NNP
cord-017142-vx3rgs4r	240	3	/	/	SYM
cord-017142-vx3rgs4r	240	4	dL	dl	NN
cord-017142-vx3rgs4r	240	5	or	or	CC
cord-017142-vx3rgs4r	240	6	with	with	IN
cord-017142-vx3rgs4r	240	7	significant	significant	JJ
cord-017142-vx3rgs4r	240	8	symptoms	symptom	NNS
cord-017142-vx3rgs4r	240	9	,	,	,
cord-017142-vx3rgs4r	240	10	other	other	JJ
cord-017142-vx3rgs4r	240	11	adjunct	adjunct	JJ
cord-017142-vx3rgs4r	240	12	therapies	therapy	NNS
cord-017142-vx3rgs4r	240	13	should	should	MD
cord-017142-vx3rgs4r	240	14	be	be	VB
cord-017142-vx3rgs4r	240	15	used	use	VBN
cord-017142-vx3rgs4r	240	16	as	as	IN
cord-017142-vx3rgs4r	240	17	a	a	DT
cord-017142-vx3rgs4r	240	18	temporizing	temporizing	JJ
cord-017142-vx3rgs4r	240	19	measure	measure	NN
cord-017142-vx3rgs4r	240	20	.	.	.
cord-017142-vx3rgs4r	241	1	Loop	loop	NN
cord-017142-vx3rgs4r	241	2	diuretics	diuretic	NNS
cord-017142-vx3rgs4r	241	3	,	,	,
cord-017142-vx3rgs4r	241	4	which	which	WDT
cord-017142-vx3rgs4r	241	5	were	be	VBD
cord-017142-vx3rgs4r	241	6	previously	previously	RB
cord-017142-vx3rgs4r	241	7	commonly	commonly	RB
cord-017142-vx3rgs4r	241	8	used	use	VBN
cord-017142-vx3rgs4r	241	9	for	for	IN
cord-017142-vx3rgs4r	241	10	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	241	11	,	,	,
cord-017142-vx3rgs4r	241	12	should	should	MD
cord-017142-vx3rgs4r	241	13	not	not	RB
cord-017142-vx3rgs4r	241	14	be	be	VB
cord-017142-vx3rgs4r	241	15	routinely	routinely	RB
cord-017142-vx3rgs4r	241	16	used	use	VBN
cord-017142-vx3rgs4r	241	17	.	.	.
cord-017142-vx3rgs4r	242	1	The	the	DT
cord-017142-vx3rgs4r	242	2	utility	utility	NN
cord-017142-vx3rgs4r	242	3	of	of	IN
cord-017142-vx3rgs4r	242	4	forced	force	VBN
cord-017142-vx3rgs4r	242	5	saline	saline	NN
cord-017142-vx3rgs4r	242	6	diuresis	diuresis	NN
cord-017142-vx3rgs4r	242	7	is	be	VBZ
cord-017142-vx3rgs4r	242	8	not	not	RB
cord-017142-vx3rgs4r	242	9	consistent	consistent	JJ
cord-017142-vx3rgs4r	242	10	;	;	:
cord-017142-vx3rgs4r	242	11	with	with	IN
cord-017142-vx3rgs4r	242	12	lower	low	JJR
cord-017142-vx3rgs4r	242	13	doses	dose	NNS
cord-017142-vx3rgs4r	242	14	,	,	,
cord-017142-vx3rgs4r	242	15	calciuresis	calciuresis	NNP
cord-017142-vx3rgs4r	242	16	is	be	VBZ
cord-017142-vx3rgs4r	242	17	an	an	DT
cord-017142-vx3rgs4r	242	18	indirect	indirect	JJ
cord-017142-vx3rgs4r	242	19	effect	effect	NN
cord-017142-vx3rgs4r	242	20	of	of	IN
cord-017142-vx3rgs4r	242	21	the	the	DT
cord-017142-vx3rgs4r	242	22	accompanying	accompany	VBG
cord-017142-vx3rgs4r	242	23	natriuresis	natriuresis	NN
cord-017142-vx3rgs4r	242	24	.	.	.
cord-017142-vx3rgs4r	243	1	To	to	TO
cord-017142-vx3rgs4r	243	2	cause	cause	VB
cord-017142-vx3rgs4r	243	3	a	a	DT
cord-017142-vx3rgs4r	243	4	direct	direct	JJ
cord-017142-vx3rgs4r	243	5	calciuretic	calciuretic	JJ
cord-017142-vx3rgs4r	243	6	effect	effect	NN
cord-017142-vx3rgs4r	243	7	,	,	,
cord-017142-vx3rgs4r	243	8	doses	dose	NNS
cord-017142-vx3rgs4r	243	9	as	as	RB
cord-017142-vx3rgs4r	243	10	high	high	JJ
cord-017142-vx3rgs4r	243	11	as	as	IN
cord-017142-vx3rgs4r	243	12	100	100	CD
cord-017142-vx3rgs4r	243	13	mg	mg	NNP
cord-017142-vx3rgs4r	243	14	/	/	SYM
cord-017142-vx3rgs4r	243	15	h	h	NNP
cord-017142-vx3rgs4r	243	16	is	be	VBZ
cord-017142-vx3rgs4r	243	17	required	require	VBN
cord-017142-vx3rgs4r	243	18	,	,	,
cord-017142-vx3rgs4r	243	19	which	which	WDT
cord-017142-vx3rgs4r	243	20	can	can	MD
cord-017142-vx3rgs4r	243	21	cause	cause	VB
cord-017142-vx3rgs4r	243	22	unwanted	unwanted	JJ
cord-017142-vx3rgs4r	243	23	metabolic	metabolic	JJ
cord-017142-vx3rgs4r	243	24	derangements	derangement	NNS
cord-017142-vx3rgs4r	243	25	and	and	CC
cord-017142-vx3rgs4r	243	26	worsening	worsen	VBG
cord-017142-vx3rgs4r	243	27	renal	renal	JJ
cord-017142-vx3rgs4r	243	28	cast	cast	NN
cord-017142-vx3rgs4r	243	29	formation	formation	NN
cord-017142-vx3rgs4r	243	30	with	with	IN
cord-017142-vx3rgs4r	243	31	risk	risk	NN
cord-017142-vx3rgs4r	243	32	of	of	IN
cord-017142-vx3rgs4r	243	33	worsening	worsen	VBG
cord-017142-vx3rgs4r	243	34	renal	renal	JJ
cord-017142-vx3rgs4r	243	35	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	243	36	[	[	-LRB-
cord-017142-vx3rgs4r	243	37	68	68	CD
cord-017142-vx3rgs4r	243	38	]	]	-RRB-
cord-017142-vx3rgs4r	243	39	.	.	.
cord-017142-vx3rgs4r	244	1	The	the	DT
cord-017142-vx3rgs4r	244	2	use	use	NN
cord-017142-vx3rgs4r	244	3	of	of	IN
cord-017142-vx3rgs4r	244	4	calcitonin	calcitonin	NN
cord-017142-vx3rgs4r	244	5	to	to	TO
cord-017142-vx3rgs4r	244	6	treat	treat	VB
cord-017142-vx3rgs4r	244	7	patients	patient	NNS
cord-017142-vx3rgs4r	244	8	with	with	IN
cord-017142-vx3rgs4r	244	9	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	244	10	is	be	VBZ
cord-017142-vx3rgs4r	244	11	limited	limit	VBN
cord-017142-vx3rgs4r	244	12	owing	owe	VBG
cord-017142-vx3rgs4r	244	13	to	to	IN
cord-017142-vx3rgs4r	244	14	its	-PRON-	PRP$
cord-017142-vx3rgs4r	244	15	inability	inability	NN
cord-017142-vx3rgs4r	244	16	to	to	TO
cord-017142-vx3rgs4r	244	17	dramatically	dramatically	RB
cord-017142-vx3rgs4r	244	18	lower	lower	VB
cord-017142-vx3rgs4r	244	19	serum	serum	NN
cord-017142-vx3rgs4r	244	20	calcium	calcium	NN
cord-017142-vx3rgs4r	244	21	levels	level	NNS
cord-017142-vx3rgs4r	244	22	.	.	.
cord-017142-vx3rgs4r	245	1	However	however	RB
cord-017142-vx3rgs4r	245	2	,	,	,
cord-017142-vx3rgs4r	245	3	it	-PRON-	PRP
cord-017142-vx3rgs4r	245	4	can	can	MD
cord-017142-vx3rgs4r	245	5	work	work	VB
cord-017142-vx3rgs4r	245	6	synergistically	synergistically	RB
cord-017142-vx3rgs4r	245	7	with	with	IN
cord-017142-vx3rgs4r	245	8	other	other	JJ
cord-017142-vx3rgs4r	245	9	therapies	therapy	NNS
cord-017142-vx3rgs4r	245	10	without	without	IN
cord-017142-vx3rgs4r	245	11	significant	significant	JJ
cord-017142-vx3rgs4r	245	12	adverse	adverse	JJ
cord-017142-vx3rgs4r	245	13	side	side	NN
cord-017142-vx3rgs4r	245	14	effects	effect	NNS
cord-017142-vx3rgs4r	245	15	until	until	IN
cord-017142-vx3rgs4r	245	16	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	245	17	can	can	MD
cord-017142-vx3rgs4r	245	18	be	be	VB
cord-017142-vx3rgs4r	245	19	initiated	initiate	VBN
cord-017142-vx3rgs4r	245	20	.	.	.
cord-017142-vx3rgs4r	246	1	Calcitonin	Calcitonin	NNP
cord-017142-vx3rgs4r	246	2	,	,	,
cord-017142-vx3rgs4r	246	3	by	by	IN
cord-017142-vx3rgs4r	246	4	inhibition	inhibition	NN
cord-017142-vx3rgs4r	246	5	of	of	IN
cord-017142-vx3rgs4r	246	6	bone	bone	NN
cord-017142-vx3rgs4r	246	7	resorption	resorption	NN
cord-017142-vx3rgs4r	246	8	and	and	CC
cord-017142-vx3rgs4r	246	9	increased	increase	VBN
cord-017142-vx3rgs4r	246	10	renal	renal	JJ
cord-017142-vx3rgs4r	246	11	calcium	calcium	NN
cord-017142-vx3rgs4r	246	12	excretion	excretion	NN
cord-017142-vx3rgs4r	246	13	,	,	,
cord-017142-vx3rgs4r	246	14	has	have	VBZ
cord-017142-vx3rgs4r	246	15	rapid	rapid	JJ
cord-017142-vx3rgs4r	246	16	onset	onset	NN
cord-017142-vx3rgs4r	246	17	of	of	IN
cord-017142-vx3rgs4r	246	18	action	action	NN
cord-017142-vx3rgs4r	246	19	and	and	CC
cord-017142-vx3rgs4r	246	20	can	can	MD
cord-017142-vx3rgs4r	246	21	lower	lower	VB
cord-017142-vx3rgs4r	246	22	calcium	calcium	NN
cord-017142-vx3rgs4r	246	23	levels	level	NNS
cord-017142-vx3rgs4r	246	24	by	by	IN
cord-017142-vx3rgs4r	246	25	1	1	CD
cord-017142-vx3rgs4r	246	26	-	-	SYM
cord-017142-vx3rgs4r	246	27	2	2	CD
cord-017142-vx3rgs4r	246	28	mg	mg	NNP
cord-017142-vx3rgs4r	246	29	/	/	SYM
cord-017142-vx3rgs4r	246	30	dL	dl	NN
cord-017142-vx3rgs4r	246	31	(	(	-LRB-
cord-017142-vx3rgs4r	246	32	0.5	0.5	CD
cord-017142-vx3rgs4r	246	33	mmol	mmol	NNP
cord-017142-vx3rgs4r	246	34	/	/	SYM
cord-017142-vx3rgs4r	246	35	L	L	NNP
cord-017142-vx3rgs4r	246	36	)	)	-RRB-
cord-017142-vx3rgs4r	246	37	.	.	.
cord-017142-vx3rgs4r	247	1	The	the	DT
cord-017142-vx3rgs4r	247	2	dose	dose	NN
cord-017142-vx3rgs4r	247	3	is	be	VBZ
cord-017142-vx3rgs4r	247	4	4	4	CD
cord-017142-vx3rgs4r	247	5	IU	IU	NNP
cord-017142-vx3rgs4r	247	6	/	/	SYM
cord-017142-vx3rgs4r	247	7	kg	kg	NNS
cord-017142-vx3rgs4r	247	8	given	give	VBN
cord-017142-vx3rgs4r	247	9	subcutaneously	subcutaneously	RB
cord-017142-vx3rgs4r	247	10	or	or	CC
cord-017142-vx3rgs4r	247	11	intramuscularly	intramuscularly	RB
cord-017142-vx3rgs4r	247	12	every	every	DT
cord-017142-vx3rgs4r	247	13	6	6	CD
cord-017142-vx3rgs4r	247	14	-	-	SYM
cord-017142-vx3rgs4r	247	15	12	12	CD
cord-017142-vx3rgs4r	247	16	h.	h.	NN
cord-017142-vx3rgs4r	248	1	The	the	DT
cord-017142-vx3rgs4r	248	2	efficacy	efficacy	NN
cord-017142-vx3rgs4r	248	3	in	in	IN
cord-017142-vx3rgs4r	248	4	general	general	JJ
cord-017142-vx3rgs4r	248	5	wears	wear	VBZ
cord-017142-vx3rgs4r	248	6	off	off	RP
cord-017142-vx3rgs4r	248	7	after	after	IN
cord-017142-vx3rgs4r	248	8	2	2	CD
cord-017142-vx3rgs4r	248	9	-	-	SYM
cord-017142-vx3rgs4r	248	10	3	3	CD
cord-017142-vx3rgs4r	248	11	days	day	NNS
cord-017142-vx3rgs4r	248	12	due	due	JJ
cord-017142-vx3rgs4r	248	13	to	to	IN
cord-017142-vx3rgs4r	248	14	the	the	DT
cord-017142-vx3rgs4r	248	15	escape	escape	NN
cord-017142-vx3rgs4r	248	16	phenomenon	phenomenon	NN
cord-017142-vx3rgs4r	248	17	(	(	-LRB-
cord-017142-vx3rgs4r	248	18	tachyphylaxis	tachyphylaxis	NNP
cord-017142-vx3rgs4r	248	19	)	)	-RRB-
cord-017142-vx3rgs4r	248	20	of	of	IN
cord-017142-vx3rgs4r	248	21	the	the	DT
cord-017142-vx3rgs4r	248	22	calcitonin	calcitonin	NN
cord-017142-vx3rgs4r	248	23	sensing	sensing	NN
cord-017142-vx3rgs4r	248	24	receptors	receptor	NNS
cord-017142-vx3rgs4r	248	25	[	[	-LRB-
cord-017142-vx3rgs4r	248	26	65	65	CD
cord-017142-vx3rgs4r	248	27	]	]	-RRB-
cord-017142-vx3rgs4r	248	28	.	.	.
cord-017142-vx3rgs4r	249	1	Preclinical	preclinical	JJ
cord-017142-vx3rgs4r	249	2	studies	study	NNS
cord-017142-vx3rgs4r	249	3	suggest	suggest	VBP
cord-017142-vx3rgs4r	249	4	tachyphylaxis	tachyphylaxis	NNP
cord-017142-vx3rgs4r	249	5	can	can	MD
cord-017142-vx3rgs4r	249	6	be	be	VB
cord-017142-vx3rgs4r	249	7	prevented	prevent	VBN
cord-017142-vx3rgs4r	249	8	with	with	IN
cord-017142-vx3rgs4r	249	9	the	the	DT
cord-017142-vx3rgs4r	249	10	addition	addition	NN
cord-017142-vx3rgs4r	249	11	of	of	IN
cord-017142-vx3rgs4r	249	12	corticosteroids	corticosteroid	NNS
cord-017142-vx3rgs4r	249	13	[	[	-LRB-
cord-017142-vx3rgs4r	249	14	27	27	CD
cord-017142-vx3rgs4r	249	15	,	,	,
cord-017142-vx3rgs4r	249	16	65	65	CD
cord-017142-vx3rgs4r	249	17	,	,	,
cord-017142-vx3rgs4r	249	18	129	129	CD
cord-017142-vx3rgs4r	249	19	]	]	-RRB-
cord-017142-vx3rgs4r	249	20	.	.	.
cord-017142-vx3rgs4r	250	1	With	with	IN
cord-017142-vx3rgs4r	250	2	its	-PRON-	PRP$
cord-017142-vx3rgs4r	250	3	anti	anti	JJ
cord-017142-vx3rgs4r	250	4	-	-	JJ
cord-017142-vx3rgs4r	250	5	MM	mm	JJ
cord-017142-vx3rgs4r	250	6	effect	effect	NN
cord-017142-vx3rgs4r	250	7	,	,	,
cord-017142-vx3rgs4r	250	8	adding	add	VBG
cord-017142-vx3rgs4r	250	9	corticosteroids	corticosteroid	NNS
cord-017142-vx3rgs4r	250	10	can	can	MD
cord-017142-vx3rgs4r	250	11	add	add	VB
cord-017142-vx3rgs4r	250	12	to	to	IN
cord-017142-vx3rgs4r	250	13	the	the	DT
cord-017142-vx3rgs4r	250	14	synergy	synergy	NN
cord-017142-vx3rgs4r	250	15	to	to	IN
cord-017142-vx3rgs4r	250	16	this	this	DT
cord-017142-vx3rgs4r	250	17	combination	combination	NN
cord-017142-vx3rgs4r	250	18	in	in	IN
cord-017142-vx3rgs4r	250	19	the	the	DT
cord-017142-vx3rgs4r	250	20	treatment	treatment	NN
cord-017142-vx3rgs4r	250	21	of	of	IN
cord-017142-vx3rgs4r	250	22	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	250	23	.	.	.
cord-017142-vx3rgs4r	251	1	The	the	DT
cord-017142-vx3rgs4r	251	2	role	role	NN
cord-017142-vx3rgs4r	251	3	of	of	IN
cord-017142-vx3rgs4r	251	4	steroids	steroid	NNS
cord-017142-vx3rgs4r	251	5	in	in	IN
cord-017142-vx3rgs4r	251	6	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	251	7	of	of	IN
cord-017142-vx3rgs4r	251	8	malignancy	malignancy	NN
cord-017142-vx3rgs4r	251	9	comes	come	VBZ
cord-017142-vx3rgs4r	251	10	from	from	IN
cord-017142-vx3rgs4r	251	11	case	case	NN
cord-017142-vx3rgs4r	251	12	reports	report	NNS
cord-017142-vx3rgs4r	251	13	and	and	CC
cord-017142-vx3rgs4r	251	14	case	case	NN
cord-017142-vx3rgs4r	251	15	series	series	NN
cord-017142-vx3rgs4r	251	16	.	.	.
cord-017142-vx3rgs4r	252	1	Corticosteroids	corticosteroid	NNS
cord-017142-vx3rgs4r	252	2	decrease	decrease	VBP
cord-017142-vx3rgs4r	252	3	calcium	calcium	NN
cord-017142-vx3rgs4r	252	4	absorption	absorption	NN
cord-017142-vx3rgs4r	252	5	from	from	IN
cord-017142-vx3rgs4r	252	6	the	the	DT
cord-017142-vx3rgs4r	252	7	gut	gut	NN
cord-017142-vx3rgs4r	252	8	,	,	,
cord-017142-vx3rgs4r	252	9	decrease	decrease	VB
cord-017142-vx3rgs4r	252	10	renal	renal	JJ
cord-017142-vx3rgs4r	252	11	tubular	tubular	JJ
cord-017142-vx3rgs4r	252	12	reabsorption	reabsorption	NN
cord-017142-vx3rgs4r	252	13	,	,	,
cord-017142-vx3rgs4r	252	14	and	and	CC
cord-017142-vx3rgs4r	252	15	promote	promote	VB
cord-017142-vx3rgs4r	252	16	excretion	excretion	NN
cord-017142-vx3rgs4r	252	17	[	[	-LRB-
cord-017142-vx3rgs4r	252	18	24	24	CD
cord-017142-vx3rgs4r	252	19	,	,	,
cord-017142-vx3rgs4r	252	20	39	39	CD
cord-017142-vx3rgs4r	252	21	]	]	-RRB-
cord-017142-vx3rgs4r	252	22	.	.	.
cord-017142-vx3rgs4r	253	1	Prednisone	Prednisone	NNP
cord-017142-vx3rgs4r	253	2	(	(	-LRB-
cord-017142-vx3rgs4r	253	3	dose	dose	NN
cord-017142-vx3rgs4r	253	4	of	of	IN
cord-017142-vx3rgs4r	253	5	20	20	CD
cord-017142-vx3rgs4r	253	6	-	-	SYM
cord-017142-vx3rgs4r	253	7	40	40	CD
cord-017142-vx3rgs4r	253	8	mg	mg	NNP
cord-017142-vx3rgs4r	253	9	/	/	SYM
cord-017142-vx3rgs4r	253	10	day	day	NN
cord-017142-vx3rgs4r	253	11	)	)	-RRB-
cord-017142-vx3rgs4r	253	12	or	or	CC
cord-017142-vx3rgs4r	253	13	IV	IV	NNP
cord-017142-vx3rgs4r	253	14	hydrocortisone	hydrocortisone	NNP
cord-017142-vx3rgs4r	253	15	(	(	-LRB-
cord-017142-vx3rgs4r	253	16	dose	dose	NN
cord-017142-vx3rgs4r	253	17	of	of	IN
cord-017142-vx3rgs4r	253	18	200	200	CD
cord-017142-vx3rgs4r	253	19	-	-	SYM
cord-017142-vx3rgs4r	253	20	300	300	CD
cord-017142-vx3rgs4r	253	21	mg	mg	NNP
cord-017142-vx3rgs4r	253	22	/	/	SYM
cord-017142-vx3rgs4r	253	23	day	day	NN
cord-017142-vx3rgs4r	253	24	)	)	-RRB-
cord-017142-vx3rgs4r	253	25	for	for	IN
cord-017142-vx3rgs4r	253	26	3	3	CD
cord-017142-vx3rgs4r	253	27	-	-	SYM
cord-017142-vx3rgs4r	253	28	5	5	CD
cord-017142-vx3rgs4r	253	29	days	day	NNS
cord-017142-vx3rgs4r	253	30	is	be	VBZ
cord-017142-vx3rgs4r	253	31	usually	usually	RB
cord-017142-vx3rgs4r	253	32	used	use	VBN
cord-017142-vx3rgs4r	253	33	in	in	IN
cord-017142-vx3rgs4r	253	34	this	this	DT
cord-017142-vx3rgs4r	253	35	setting	setting	NN
cord-017142-vx3rgs4r	253	36	.	.	.
cord-017142-vx3rgs4r	254	1	This	this	DT
cord-017142-vx3rgs4r	254	2	dose	dose	NN
cord-017142-vx3rgs4r	254	3	,	,	,
cord-017142-vx3rgs4r	254	4	which	which	WDT
cord-017142-vx3rgs4r	254	5	is	be	VBZ
cord-017142-vx3rgs4r	254	6	effective	effective	JJ
cord-017142-vx3rgs4r	254	7	in	in	IN
cord-017142-vx3rgs4r	254	8	patients	patient	NNS
cord-017142-vx3rgs4r	254	9	with	with	IN
cord-017142-vx3rgs4r	254	10	chronic	chronic	JJ
cord-017142-vx3rgs4r	254	11	granulomatous	granulomatous	JJ
cord-017142-vx3rgs4r	254	12	diseases	disease	NNS
cord-017142-vx3rgs4r	254	13	(	(	-LRB-
cord-017142-vx3rgs4r	254	14	e.g.	e.g.	RB
cord-017142-vx3rgs4r	254	15	,	,	,
cord-017142-vx3rgs4r	254	16	sarcoidosis	sarcoidosis	NN
cord-017142-vx3rgs4r	254	17	)	)	-RRB-
cord-017142-vx3rgs4r	254	18	and	and	CC
cord-017142-vx3rgs4r	254	19	malignancies	malignancy	NNS
cord-017142-vx3rgs4r	254	20	such	such	JJ
cord-017142-vx3rgs4r	254	21	as	as	IN
cord-017142-vx3rgs4r	254	22	lymphoma	lymphoma	NN
cord-017142-vx3rgs4r	254	23	,	,	,
cord-017142-vx3rgs4r	254	24	may	may	MD
cord-017142-vx3rgs4r	254	25	be	be	VB
cord-017142-vx3rgs4r	254	26	suboptimal	suboptimal	JJ
cord-017142-vx3rgs4r	254	27	for	for	IN
cord-017142-vx3rgs4r	254	28	patients	patient	NNS
cord-017142-vx3rgs4r	254	29	with	with	IN
cord-017142-vx3rgs4r	254	30	MM	MM	NNP
cord-017142-vx3rgs4r	254	31	due	due	IN
cord-017142-vx3rgs4r	254	32	to	to	IN
cord-017142-vx3rgs4r	254	33	the	the	DT
cord-017142-vx3rgs4r	254	34	direct	direct	JJ
cord-017142-vx3rgs4r	254	35	osteolytic	osteolytic	JJ
cord-017142-vx3rgs4r	254	36	action	action	NN
cord-017142-vx3rgs4r	254	37	of	of	IN
cord-017142-vx3rgs4r	254	38	MM	MM	NNP
cord-017142-vx3rgs4r	254	39	cells	cell	NNS
cord-017142-vx3rgs4r	254	40	.	.	.
cord-017142-vx3rgs4r	255	1	If	if	IN
cord-017142-vx3rgs4r	255	2	clinical	clinical	JJ
cord-017142-vx3rgs4r	255	3	status	status	NN
cord-017142-vx3rgs4r	255	4	permits	permit	NNS
cord-017142-vx3rgs4r	255	5	,	,	,
cord-017142-vx3rgs4r	255	6	dexamethasone	dexamethasone	NN
cord-017142-vx3rgs4r	255	7	should	should	MD
cord-017142-vx3rgs4r	255	8	be	be	VB
cord-017142-vx3rgs4r	255	9	considered	consider	VBN
cord-017142-vx3rgs4r	255	10	at	at	IN
cord-017142-vx3rgs4r	255	11	MM	MM	NNP
cord-017142-vx3rgs4r	255	12	treatment	treatment	NN
cord-017142-vx3rgs4r	255	13	doses	dose	NNS
cord-017142-vx3rgs4r	255	14	ranging	range	VBG
cord-017142-vx3rgs4r	255	15	from	from	IN
cord-017142-vx3rgs4r	255	16	20	20	CD
cord-017142-vx3rgs4r	255	17	to	to	TO
cord-017142-vx3rgs4r	255	18	40	40	CD
cord-017142-vx3rgs4r	255	19	mg	mg	NNP
cord-017142-vx3rgs4r	255	20	weekly	weekly	NN
cord-017142-vx3rgs4r	255	21	or	or	CC
cord-017142-vx3rgs4r	255	22	20	20	CD
cord-017142-vx3rgs4r	255	23	to	to	TO
cord-017142-vx3rgs4r	255	24	40	40	CD
cord-017142-vx3rgs4r	255	25	mg	mg	NNS
cord-017142-vx3rgs4r	255	26	daily	daily	RB
cord-017142-vx3rgs4r	255	27	on	on	IN
cord-017142-vx3rgs4r	255	28	a	a	DT
cord-017142-vx3rgs4r	255	29	4	4	CD
cord-017142-vx3rgs4r	255	30	days	day	NNS
cord-017142-vx3rgs4r	255	31	on	on	RB
cord-017142-vx3rgs4r	255	32	,	,	,
cord-017142-vx3rgs4r	255	33	4	4	CD
cord-017142-vx3rgs4r	255	34	days	day	NNS
cord-017142-vx3rgs4r	255	35	off	off	IN
cord-017142-vx3rgs4r	255	36	schedule	schedule	NN
cord-017142-vx3rgs4r	255	37	.	.	.
cord-017142-vx3rgs4r	256	1	Intravenous	intravenous	JJ
cord-017142-vx3rgs4r	256	2	bisphosphonates	bisphosphonate	NNS
cord-017142-vx3rgs4r	256	3	(	(	-LRB-
cord-017142-vx3rgs4r	256	4	pamidronate	pamidronate	NNP
cord-017142-vx3rgs4r	256	5	,	,	,
cord-017142-vx3rgs4r	256	6	zoledronic	zoledronic	NNP
cord-017142-vx3rgs4r	256	7	acid	acid	NN
cord-017142-vx3rgs4r	256	8	,	,	,
cord-017142-vx3rgs4r	256	9	ibandronate	ibandronate	NNP
cord-017142-vx3rgs4r	256	10	)	)	-RRB-
cord-017142-vx3rgs4r	256	11	work	work	NN
cord-017142-vx3rgs4r	256	12	by	by	IN
cord-017142-vx3rgs4r	256	13	blocking	block	VBG
cord-017142-vx3rgs4r	256	14	osteoclast	osteoclast	NN
cord-017142-vx3rgs4r	256	15	-	-	HYPH
cord-017142-vx3rgs4r	256	16	mediated	mediate	VBN
cord-017142-vx3rgs4r	256	17	bone	bone	NN
cord-017142-vx3rgs4r	256	18	resorption	resorption	NN
cord-017142-vx3rgs4r	256	19	.	.	.
cord-017142-vx3rgs4r	257	1	Intravenous	intravenous	JJ
cord-017142-vx3rgs4r	257	2	zoledronic	zoledronic	NN
cord-017142-vx3rgs4r	257	3	acid	acid	NN
cord-017142-vx3rgs4r	257	4	is	be	VBZ
cord-017142-vx3rgs4r	257	5	more	more	RBR
cord-017142-vx3rgs4r	257	6	routinely	routinely	RB
cord-017142-vx3rgs4r	257	7	used	use	VBN
cord-017142-vx3rgs4r	257	8	than	than	IN
cord-017142-vx3rgs4r	257	9	other	other	JJ
cord-017142-vx3rgs4r	257	10	drugs	drug	NNS
cord-017142-vx3rgs4r	257	11	in	in	IN
cord-017142-vx3rgs4r	257	12	this	this	DT
cord-017142-vx3rgs4r	257	13	category	category	NN
cord-017142-vx3rgs4r	257	14	due	due	IN
cord-017142-vx3rgs4r	257	15	to	to	IN
cord-017142-vx3rgs4r	257	16	its	-PRON-	PRP$
cord-017142-vx3rgs4r	257	17	higher	high	JJR
cord-017142-vx3rgs4r	257	18	potency	potency	NN
cord-017142-vx3rgs4r	257	19	,	,	,
cord-017142-vx3rgs4r	257	20	efficacy	efficacy	NN
cord-017142-vx3rgs4r	257	21	,	,	,
cord-017142-vx3rgs4r	257	22	and	and	CC
cord-017142-vx3rgs4r	257	23	shorter	short	JJR
cord-017142-vx3rgs4r	257	24	infusion	infusion	NN
cord-017142-vx3rgs4r	257	25	time	time	NN
cord-017142-vx3rgs4r	257	26	(	(	-LRB-
cord-017142-vx3rgs4r	257	27	15	15	CD
cord-017142-vx3rgs4r	257	28	min	min	NNP
cord-017142-vx3rgs4r	257	29	)	)	-RRB-
cord-017142-vx3rgs4r	257	30	,	,	,
cord-017142-vx3rgs4r	257	31	when	when	WRB
cord-017142-vx3rgs4r	257	32	compared	compare	VBN
cord-017142-vx3rgs4r	257	33	to	to	IN
cord-017142-vx3rgs4r	257	34	ibandronate	ibandronate	VB
cord-017142-vx3rgs4r	257	35	and	and	CC
cord-017142-vx3rgs4r	257	36	pamidronate	pamidronate	VB
cord-017142-vx3rgs4r	257	37	[	[	-LRB-
cord-017142-vx3rgs4r	257	38	76	76	CD
cord-017142-vx3rgs4r	257	39	,	,	,
cord-017142-vx3rgs4r	257	40	96	96	CD
cord-017142-vx3rgs4r	257	41	,	,	,
cord-017142-vx3rgs4r	257	42	97	97	CD
cord-017142-vx3rgs4r	257	43	,	,	,
cord-017142-vx3rgs4r	257	44	111	111	CD
cord-017142-vx3rgs4r	257	45	]	]	-RRB-
cord-017142-vx3rgs4r	257	46	.	.	.
cord-017142-vx3rgs4r	258	1	Bisphosphonates	Bisphosphonates	NNP
cord-017142-vx3rgs4r	258	2	have	have	VBP
cord-017142-vx3rgs4r	258	3	an	an	DT
cord-017142-vx3rgs4r	258	4	established	establish	VBN
cord-017142-vx3rgs4r	258	5	role	role	NN
cord-017142-vx3rgs4r	258	6	in	in	IN
cord-017142-vx3rgs4r	258	7	severe	severe	JJ
cord-017142-vx3rgs4r	258	8	or	or	CC
cord-017142-vx3rgs4r	258	9	symptomatic	symptomatic	JJ
cord-017142-vx3rgs4r	258	10	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	258	11	,	,	,
cord-017142-vx3rgs4r	258	12	but	but	CC
cord-017142-vx3rgs4r	258	13	often	often	RB
cord-017142-vx3rgs4r	258	14	it	-PRON-	PRP
cord-017142-vx3rgs4r	258	15	is	be	VBZ
cord-017142-vx3rgs4r	258	16	challenging	challenge	VBG
cord-017142-vx3rgs4r	258	17	to	to	TO
cord-017142-vx3rgs4r	258	18	administer	administer	VB
cord-017142-vx3rgs4r	258	19	them	-PRON-	PRP
cord-017142-vx3rgs4r	258	20	upfront	upfront	JJ
cord-017142-vx3rgs4r	258	21	for	for	IN
cord-017142-vx3rgs4r	258	22	MM	MM	NNP
cord-017142-vx3rgs4r	258	23	patients	patient	NNS
cord-017142-vx3rgs4r	258	24	due	due	JJ
cord-017142-vx3rgs4r	258	25	to	to	IN
cord-017142-vx3rgs4r	258	26	the	the	DT
cord-017142-vx3rgs4r	258	27	renal	renal	JJ
cord-017142-vx3rgs4r	258	28	function	function	NN
cord-017142-vx3rgs4r	258	29	-	-	HYPH
cord-017142-vx3rgs4r	258	30	based	base	VBN
cord-017142-vx3rgs4r	258	31	dose	dose	NN
cord-017142-vx3rgs4r	258	32	limitation	limitation	NN
cord-017142-vx3rgs4r	258	33	[	[	-LRB-
cord-017142-vx3rgs4r	258	34	19	19	CD
cord-017142-vx3rgs4r	258	35	]	]	-RRB-
cord-017142-vx3rgs4r	258	36	.	.	.
cord-017142-vx3rgs4r	259	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	259	2	also	also	RB
cord-017142-vx3rgs4r	259	3	has	have	VBZ
cord-017142-vx3rgs4r	259	4	slow	slow	JJ
cord-017142-vx3rgs4r	259	5	onset	onset	NN
cord-017142-vx3rgs4r	259	6	of	of	IN
cord-017142-vx3rgs4r	259	7	action	action	NN
cord-017142-vx3rgs4r	259	8	and	and	CC
cord-017142-vx3rgs4r	259	9	reaches	reach	VBZ
cord-017142-vx3rgs4r	259	10	peak	peak	NN
cord-017142-vx3rgs4r	259	11	in	in	IN
cord-017142-vx3rgs4r	259	12	about	about	RB
cord-017142-vx3rgs4r	259	13	2	2	CD
cord-017142-vx3rgs4r	259	14	-	-	SYM
cord-017142-vx3rgs4r	259	15	5	5	CD
cord-017142-vx3rgs4r	259	16	days	day	NNS
cord-017142-vx3rgs4r	259	17	;	;	:
cord-017142-vx3rgs4r	259	18	therefore	therefore	RB
cord-017142-vx3rgs4r	259	19	it	-PRON-	PRP
cord-017142-vx3rgs4r	259	20	needs	need	VBZ
cord-017142-vx3rgs4r	259	21	to	to	TO
cord-017142-vx3rgs4r	259	22	be	be	VB
cord-017142-vx3rgs4r	259	23	used	use	VBN
cord-017142-vx3rgs4r	259	24	in	in	IN
cord-017142-vx3rgs4r	259	25	a	a	DT
cord-017142-vx3rgs4r	259	26	combinatorial	combinatorial	JJ
cord-017142-vx3rgs4r	259	27	approach	approach	NN
cord-017142-vx3rgs4r	259	28	.	.	.
cord-017142-vx3rgs4r	260	1	Denosumab	Denosumab	NNP
cord-017142-vx3rgs4r	260	2	,	,	,
cord-017142-vx3rgs4r	260	3	on	on	IN
cord-017142-vx3rgs4r	260	4	the	the	DT
cord-017142-vx3rgs4r	260	5	other	other	JJ
cord-017142-vx3rgs4r	260	6	hand	hand	NN
cord-017142-vx3rgs4r	260	7	,	,	,
cord-017142-vx3rgs4r	260	8	has	have	VBZ
cord-017142-vx3rgs4r	260	9	a	a	DT
cord-017142-vx3rgs4r	260	10	renally	renally	NN
cord-017142-vx3rgs4r	260	11	independent	independent	JJ
cord-017142-vx3rgs4r	260	12	clearance	clearance	NN
cord-017142-vx3rgs4r	260	13	mechanism	mechanism	NN
cord-017142-vx3rgs4r	260	14	and	and	CC
cord-017142-vx3rgs4r	260	15	hence	hence	RB
cord-017142-vx3rgs4r	260	16	does	do	VBZ
cord-017142-vx3rgs4r	260	17	not	not	RB
cord-017142-vx3rgs4r	260	18	require	require	VB
cord-017142-vx3rgs4r	260	19	kidney	kidney	NN
cord-017142-vx3rgs4r	260	20	functionbased	functionbase	VBN
cord-017142-vx3rgs4r	260	21	dosing	dosing	NN
cord-017142-vx3rgs4r	260	22	adjustments	adjustment	NNS
cord-017142-vx3rgs4r	260	23	.	.	.
cord-017142-vx3rgs4r	261	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	261	2	is	be	VBZ
cord-017142-vx3rgs4r	261	3	currently	currently	RB
cord-017142-vx3rgs4r	261	4	FDA	FDA	NNP
cord-017142-vx3rgs4r	261	5	approved	approve	VBN
cord-017142-vx3rgs4r	261	6	to	to	TO
cord-017142-vx3rgs4r	261	7	treat	treat	VB
cord-017142-vx3rgs4r	261	8	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	261	9	of	of	IN
cord-017142-vx3rgs4r	261	10	malignancy	malignancy	NN
cord-017142-vx3rgs4r	261	11	refractory	refractory	JJ
cord-017142-vx3rgs4r	261	12	to	to	IN
cord-017142-vx3rgs4r	261	13	bisphosphonate	bisphosphonate	NNP
cord-017142-vx3rgs4r	261	14	therapy	therapy	NN
cord-017142-vx3rgs4r	261	15	and	and	CC
cord-017142-vx3rgs4r	261	16	is	be	VBZ
cord-017142-vx3rgs4r	261	17	dosed	dose	VBN
cord-017142-vx3rgs4r	261	18	at	at	IN
cord-017142-vx3rgs4r	261	19	120	120	CD
cord-017142-vx3rgs4r	261	20	mg	mg	NNP
cord-017142-vx3rgs4r	261	21	subcutaneous	subcutaneous	JJ
cord-017142-vx3rgs4r	261	22	injection	injection	NN
cord-017142-vx3rgs4r	261	23	every	every	DT
cord-017142-vx3rgs4r	261	24	4	4	CD
cord-017142-vx3rgs4r	261	25	weeks	week	NNS
cord-017142-vx3rgs4r	261	26	with	with	IN
cord-017142-vx3rgs4r	261	27	additional	additional	JJ
cord-017142-vx3rgs4r	261	28	doses	dose	NNS
cord-017142-vx3rgs4r	261	29	of	of	IN
cord-017142-vx3rgs4r	261	30	120	120	CD
cord-017142-vx3rgs4r	261	31	mg	mg	NNS
cord-017142-vx3rgs4r	261	32	on	on	IN
cord-017142-vx3rgs4r	261	33	days	day	NNS
cord-017142-vx3rgs4r	261	34	8	8	CD
cord-017142-vx3rgs4r	261	35	and	and	CC
cord-017142-vx3rgs4r	261	36	15	15	CD
cord-017142-vx3rgs4r	261	37	of	of	IN
cord-017142-vx3rgs4r	261	38	the	the	DT
cord-017142-vx3rgs4r	261	39	first	first	JJ
cord-017142-vx3rgs4r	261	40	month	month	NN
cord-017142-vx3rgs4r	261	41	of	of	IN
cord-017142-vx3rgs4r	261	42	therapy	therapy	NN
cord-017142-vx3rgs4r	261	43	[	[	-LRB-
cord-017142-vx3rgs4r	261	44	37	37	CD
cord-017142-vx3rgs4r	261	45	,	,	,
cord-017142-vx3rgs4r	261	46	50	50	CD
cord-017142-vx3rgs4r	261	47	]	]	-RRB-
cord-017142-vx3rgs4r	261	48	.	.	.
cord-017142-vx3rgs4r	262	1	Mithramycin	Mithramycin	NNS
cord-017142-vx3rgs4r	262	2	and	and	CC
cord-017142-vx3rgs4r	262	3	gallium	gallium	NN
cord-017142-vx3rgs4r	262	4	nitrate	nitrate	NN
cord-017142-vx3rgs4r	262	5	are	be	VBP
cord-017142-vx3rgs4r	262	6	drugs	drug	NNS
cord-017142-vx3rgs4r	262	7	of	of	IN
cord-017142-vx3rgs4r	262	8	historical	historical	JJ
cord-017142-vx3rgs4r	262	9	interest	interest	NN
cord-017142-vx3rgs4r	262	10	and	and	CC
cord-017142-vx3rgs4r	262	11	are	be	VBP
cord-017142-vx3rgs4r	262	12	not	not	RB
cord-017142-vx3rgs4r	262	13	currently	currently	RB
cord-017142-vx3rgs4r	262	14	used	use	VBN
cord-017142-vx3rgs4r	262	15	in	in	IN
cord-017142-vx3rgs4r	262	16	the	the	DT
cord-017142-vx3rgs4r	262	17	standard	standard	JJ
cord-017142-vx3rgs4r	262	18	setting	setting	NN
cord-017142-vx3rgs4r	262	19	.	.	.
cord-017142-vx3rgs4r	263	1	In	in	IN
cord-017142-vx3rgs4r	263	2	refractory	refractory	JJ
cord-017142-vx3rgs4r	263	3	cases	case	NNS
cord-017142-vx3rgs4r	263	4	of	of	IN
cord-017142-vx3rgs4r	263	5	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	263	6	seen	see	VBN
cord-017142-vx3rgs4r	263	7	in	in	IN
cord-017142-vx3rgs4r	263	8	advanced	advanced	JJ
cord-017142-vx3rgs4r	263	9	MM	mm	NN
cord-017142-vx3rgs4r	263	10	and	and	CC
cord-017142-vx3rgs4r	263	11	kidney	kidney	NN
cord-017142-vx3rgs4r	263	12	involvement	involvement	NN
cord-017142-vx3rgs4r	263	13	,	,	,
cord-017142-vx3rgs4r	263	14	with	with	IN
cord-017142-vx3rgs4r	263	15	impending	impending	JJ
cord-017142-vx3rgs4r	263	16	cardiovascular	cardiovascular	JJ
cord-017142-vx3rgs4r	263	17	or	or	CC
cord-017142-vx3rgs4r	263	18	cerebrovascular	cerebrovascular	JJ
cord-017142-vx3rgs4r	263	19	deterioration	deterioration	NN
cord-017142-vx3rgs4r	263	20	,	,	,
cord-017142-vx3rgs4r	263	21	hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	264	1	Ca	ca	NN
cord-017142-vx3rgs4r	264	2	2	2	CD
cord-017142-vx3rgs4r	264	3	+	+	CD
cord-017142-vx3rgs4r	265	1	-free	-free	CD
cord-017142-vx3rgs4r	265	2	dialysate	dialysate	NNP
cord-017142-vx3rgs4r	265	3	should	should	MD
cord-017142-vx3rgs4r	265	4	be	be	VB
cord-017142-vx3rgs4r	265	5	strongly	strongly	RB
cord-017142-vx3rgs4r	265	6	considered	consider	VBN
cord-017142-vx3rgs4r	265	7	.	.	.
cord-017142-vx3rgs4r	266	1	Tumor	tumor	NN
cord-017142-vx3rgs4r	266	2	lysis	lysis	NN
cord-017142-vx3rgs4r	266	3	syndrome	syndrome	NN
cord-017142-vx3rgs4r	266	4	:	:	:
cord-017142-vx3rgs4r	266	5	Due	due	IN
cord-017142-vx3rgs4r	266	6	to	to	IN
cord-017142-vx3rgs4r	266	7	the	the	DT
cord-017142-vx3rgs4r	266	8	low	low	JJ
cord-017142-vx3rgs4r	266	9	proliferative	proliferative	JJ
cord-017142-vx3rgs4r	266	10	activity	activity	NN
cord-017142-vx3rgs4r	266	11	of	of	IN
cord-017142-vx3rgs4r	266	12	plasma	plasma	NN
cord-017142-vx3rgs4r	266	13	cells	cell	NNS
cord-017142-vx3rgs4r	266	14	which	which	WDT
cord-017142-vx3rgs4r	266	15	is	be	VBZ
cord-017142-vx3rgs4r	266	16	<	<	NNP
cord-017142-vx3rgs4r	266	17	10	10	CD
cord-017142-vx3rgs4r	266	18	%	%	NN
cord-017142-vx3rgs4r	266	19	in	in	IN
cord-017142-vx3rgs4r	266	20	majority	majority	NN
cord-017142-vx3rgs4r	266	21	of	of	IN
cord-017142-vx3rgs4r	266	22	patients	patient	NNS
cord-017142-vx3rgs4r	266	23	,	,	,
cord-017142-vx3rgs4r	266	24	TLS	TLS	NNP
cord-017142-vx3rgs4r	266	25	is	be	VBZ
cord-017142-vx3rgs4r	266	26	extremely	extremely	RB
cord-017142-vx3rgs4r	266	27	uncommon	uncommon	JJ
cord-017142-vx3rgs4r	266	28	in	in	IN
cord-017142-vx3rgs4r	266	29	MM	MM	NNP
cord-017142-vx3rgs4r	266	30	[	[	-LRB-
cord-017142-vx3rgs4r	266	31	18	18	CD
cord-017142-vx3rgs4r	266	32	,	,	,
cord-017142-vx3rgs4r	266	33	79	79	CD
cord-017142-vx3rgs4r	266	34	]	]	-RRB-
cord-017142-vx3rgs4r	266	35	.	.	.
cord-017142-vx3rgs4r	267	1	MM	MM	NNP
cord-017142-vx3rgs4r	267	2	patients	patient	NNS
cord-017142-vx3rgs4r	267	3	who	who	WP
cord-017142-vx3rgs4r	267	4	are	be	VBP
cord-017142-vx3rgs4r	267	5	likely	likely	JJ
cord-017142-vx3rgs4r	267	6	to	to	TO
cord-017142-vx3rgs4r	267	7	be	be	VB
cord-017142-vx3rgs4r	267	8	at	at	IN
cord-017142-vx3rgs4r	267	9	risk	risk	NN
cord-017142-vx3rgs4r	267	10	are	be	VBP
cord-017142-vx3rgs4r	267	11	patients	patient	NNS
cord-017142-vx3rgs4r	267	12	with	with	IN
cord-017142-vx3rgs4r	267	13	high	high	JJ
cord-017142-vx3rgs4r	267	14	tumor	tumor	NN
cord-017142-vx3rgs4r	267	15	burden	burden	NN
cord-017142-vx3rgs4r	267	16	(	(	-LRB-
cord-017142-vx3rgs4r	267	17	as	as	IN
cord-017142-vx3rgs4r	267	18	noted	note	VBN
cord-017142-vx3rgs4r	267	19	by	by	IN
cord-017142-vx3rgs4r	267	20	an	an	DT
cord-017142-vx3rgs4r	267	21	increased	increase	VBN
cord-017142-vx3rgs4r	267	22	serum	serum	NN
cord-017142-vx3rgs4r	267	23	lactate	lactate	NN
cord-017142-vx3rgs4r	267	24	dehydrogenase	dehydrogenase	NN
cord-017142-vx3rgs4r	267	25	and	and	CC
cord-017142-vx3rgs4r	267	26	beta-2	beta-2	NN
cord-017142-vx3rgs4r	267	27	microglobulin	microglobulin	NN
cord-017142-vx3rgs4r	267	28	)	)	-RRB-
cord-017142-vx3rgs4r	267	29	,	,	,
cord-017142-vx3rgs4r	267	30	diffuse	diffuse	VB
cord-017142-vx3rgs4r	267	31	bone	bone	NN
cord-017142-vx3rgs4r	267	32	marrow	marrow	NN
cord-017142-vx3rgs4r	267	33	disease	disease	NN
cord-017142-vx3rgs4r	267	34	(	(	-LRB-
cord-017142-vx3rgs4r	267	35	plasma	plasma	NN
cord-017142-vx3rgs4r	267	36	cells	cell	NNS
cord-017142-vx3rgs4r	267	37	>	>	XX
cord-017142-vx3rgs4r	267	38	70	70	CD
cord-017142-vx3rgs4r	267	39	%	%	NN
cord-017142-vx3rgs4r	267	40	of	of	IN
cord-017142-vx3rgs4r	267	41	all	all	DT
cord-017142-vx3rgs4r	267	42	nucleated	nucleated	JJ
cord-017142-vx3rgs4r	267	43	cells	cell	NNS
cord-017142-vx3rgs4r	267	44	as	as	IN
cord-017142-vx3rgs4r	267	45	per	per	IN
cord-017142-vx3rgs4r	267	46	a	a	DT
cord-017142-vx3rgs4r	267	47	case	case	NN
cord-017142-vx3rgs4r	267	48	series	series	NN
cord-017142-vx3rgs4r	267	49	)	)	-RRB-
cord-017142-vx3rgs4r	267	50	,	,	,
cord-017142-vx3rgs4r	267	51	extensive	extensive	JJ
cord-017142-vx3rgs4r	267	52	skeletal	skeletal	JJ
cord-017142-vx3rgs4r	267	53	involvement	involvement	NN
cord-017142-vx3rgs4r	267	54	,	,	,
cord-017142-vx3rgs4r	267	55	high	high	JJ
cord-017142-vx3rgs4r	267	56	-	-	HYPH
cord-017142-vx3rgs4r	267	57	risk	risk	NN
cord-017142-vx3rgs4r	267	58	cytogenetics	cytogenetic	NNS
cord-017142-vx3rgs4r	267	59	,	,	,
cord-017142-vx3rgs4r	267	60	and	and	CC
cord-017142-vx3rgs4r	267	61	plasmablastic	plasmablastic	JJ
cord-017142-vx3rgs4r	267	62	morphology	morphology	NN
cord-017142-vx3rgs4r	267	63	[	[	-LRB-
cord-017142-vx3rgs4r	267	64	35	35	CD
cord-017142-vx3rgs4r	267	65	,	,	,
cord-017142-vx3rgs4r	267	66	46	46	CD
cord-017142-vx3rgs4r	267	67	]	]	-RRB-
cord-017142-vx3rgs4r	267	68	.	.	.
cord-017142-vx3rgs4r	268	1	There	there	EX
cord-017142-vx3rgs4r	268	2	are	be	VBP
cord-017142-vx3rgs4r	268	3	reports	report	NNS
cord-017142-vx3rgs4r	268	4	of	of	IN
cord-017142-vx3rgs4r	268	5	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	268	6	,	,	,
cord-017142-vx3rgs4r	268	7	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	268	8	,	,	,
cord-017142-vx3rgs4r	268	9	and	and	CC
cord-017142-vx3rgs4r	268	10	steroid	steroid	NN
cord-017142-vx3rgs4r	268	11	associated	associate	VBD
cord-017142-vx3rgs4r	268	12	TLS	TLS	NNP
cord-017142-vx3rgs4r	268	13	[	[	-LRB-
cord-017142-vx3rgs4r	268	14	23	23	CD
cord-017142-vx3rgs4r	268	15	,	,	,
cord-017142-vx3rgs4r	268	16	38	38	CD
cord-017142-vx3rgs4r	268	17	]	]	-RRB-
cord-017142-vx3rgs4r	268	18	.	.	.
cord-017142-vx3rgs4r	269	1	Tumor	tumor	NN
cord-017142-vx3rgs4r	269	2	lysis	lysis	NN
cord-017142-vx3rgs4r	269	3	syndrome	syndrome	NN
cord-017142-vx3rgs4r	269	4	manifests	manifest	VBZ
cord-017142-vx3rgs4r	269	5	due	due	JJ
cord-017142-vx3rgs4r	269	6	to	to	IN
cord-017142-vx3rgs4r	269	7	lysis	lysis	NN
cord-017142-vx3rgs4r	269	8	of	of	IN
cord-017142-vx3rgs4r	269	9	massive	massive	JJ
cord-017142-vx3rgs4r	269	10	numbers	number	NNS
cord-017142-vx3rgs4r	269	11	of	of	IN
cord-017142-vx3rgs4r	269	12	tumor	tumor	NN
cord-017142-vx3rgs4r	269	13	cells	cell	NNS
cord-017142-vx3rgs4r	269	14	releasing	release	VBG
cord-017142-vx3rgs4r	269	15	intracellular	intracellular	JJ
cord-017142-vx3rgs4r	269	16	potassium	potassium	NN
cord-017142-vx3rgs4r	269	17	and	and	CC
cord-017142-vx3rgs4r	269	18	phosphorous	phosphorous	JJ
cord-017142-vx3rgs4r	269	19	causing	cause	VBG
cord-017142-vx3rgs4r	269	20	hyperkalemia	hyperkalemia	NN
cord-017142-vx3rgs4r	269	21	and	and	CC
cord-017142-vx3rgs4r	269	22	hyperphosphatemia	hyperphosphatemia	NN
cord-017142-vx3rgs4r	269	23	.	.	.
cord-017142-vx3rgs4r	270	1	This	this	DT
cord-017142-vx3rgs4r	270	2	causes	cause	VBZ
cord-017142-vx3rgs4r	270	3	calcium	calcium	NN
cord-017142-vx3rgs4r	270	4	to	to	TO
cord-017142-vx3rgs4r	270	5	precipitate	precipitate	VB
cord-017142-vx3rgs4r	270	6	as	as	IN
cord-017142-vx3rgs4r	270	7	calcium	calcium	NN
cord-017142-vx3rgs4r	270	8	phosphate	phosphate	NN
cord-017142-vx3rgs4r	270	9	in	in	IN
cord-017142-vx3rgs4r	270	10	tissues	tissue	NNS
cord-017142-vx3rgs4r	270	11	causing	cause	VBG
cord-017142-vx3rgs4r	270	12	secondary	secondary	JJ
cord-017142-vx3rgs4r	270	13	hypocalcemia	hypocalcemia	NN
cord-017142-vx3rgs4r	270	14	.	.	.
cord-017142-vx3rgs4r	271	1	Hyperuricemia	Hyperuricemia	NNP
cord-017142-vx3rgs4r	271	2	results	result	VBZ
cord-017142-vx3rgs4r	271	3	from	from	IN
cord-017142-vx3rgs4r	271	4	the	the	DT
cord-017142-vx3rgs4r	271	5	breakdown	breakdown	NN
cord-017142-vx3rgs4r	271	6	of	of	IN
cord-017142-vx3rgs4r	271	7	nucleic	nucleic	JJ
cord-017142-vx3rgs4r	271	8	acids	acid	NNS
cord-017142-vx3rgs4r	271	9	in	in	IN
cord-017142-vx3rgs4r	271	10	the	the	DT
cord-017142-vx3rgs4r	271	11	tumor	tumor	NN
cord-017142-vx3rgs4r	271	12	cells	cell	NNS
cord-017142-vx3rgs4r	271	13	.	.	.
cord-017142-vx3rgs4r	272	1	The	the	DT
cord-017142-vx3rgs4r	272	2	resultant	resultant	JJ
cord-017142-vx3rgs4r	272	3	metabolic	metabolic	JJ
cord-017142-vx3rgs4r	272	4	derangement	derangement	NN
cord-017142-vx3rgs4r	272	5	,	,	,
cord-017142-vx3rgs4r	272	6	if	if	IN
cord-017142-vx3rgs4r	272	7	left	leave	VBN
cord-017142-vx3rgs4r	272	8	untreated	untreated	JJ
cord-017142-vx3rgs4r	272	9	,	,	,
cord-017142-vx3rgs4r	272	10	can	can	MD
cord-017142-vx3rgs4r	272	11	progress	progress	VB
cord-017142-vx3rgs4r	272	12	to	to	IN
cord-017142-vx3rgs4r	272	13	kidney	kidney	NN
cord-017142-vx3rgs4r	272	14	failure	failure	NN
cord-017142-vx3rgs4r	272	15	,	,	,
cord-017142-vx3rgs4r	272	16	mental	mental	JJ
cord-017142-vx3rgs4r	272	17	status	status	NN
cord-017142-vx3rgs4r	272	18	changes	change	NNS
cord-017142-vx3rgs4r	272	19	,	,	,
cord-017142-vx3rgs4r	272	20	seizures	seizure	NNS
cord-017142-vx3rgs4r	272	21	,	,	,
cord-017142-vx3rgs4r	272	22	arrhythmias	arrhythmias	RB
cord-017142-vx3rgs4r	272	23	,	,	,
cord-017142-vx3rgs4r	272	24	and	and	CC
cord-017142-vx3rgs4r	272	25	even	even	RB
cord-017142-vx3rgs4r	272	26	death	death	NN
cord-017142-vx3rgs4r	272	27	.	.	.
cord-017142-vx3rgs4r	273	1	Diagnosing	diagnose	VBG
cord-017142-vx3rgs4r	273	2	TLS	TLS	NNP
cord-017142-vx3rgs4r	273	3	can	can	MD
cord-017142-vx3rgs4r	273	4	be	be	VB
cord-017142-vx3rgs4r	273	5	challenging	challenging	JJ
cord-017142-vx3rgs4r	273	6	in	in	IN
cord-017142-vx3rgs4r	273	7	patients	patient	NNS
cord-017142-vx3rgs4r	273	8	with	with	IN
cord-017142-vx3rgs4r	273	9	MM	MM	NNP
cord-017142-vx3rgs4r	273	10	due	due	IN
cord-017142-vx3rgs4r	273	11	to	to	IN
cord-017142-vx3rgs4r	273	12	its	-PRON-	PRP$
cord-017142-vx3rgs4r	273	13	uncommon	uncommon	JJ
cord-017142-vx3rgs4r	273	14	association	association	NN
cord-017142-vx3rgs4r	273	15	and	and	CC
cord-017142-vx3rgs4r	273	16	often	often	RB
cord-017142-vx3rgs4r	273	17	seen	see	VBN
cord-017142-vx3rgs4r	273	18	associated	associate	VBN
cord-017142-vx3rgs4r	273	19	renal	renal	JJ
cord-017142-vx3rgs4r	273	20	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	273	21	[	[	-LRB-
cord-017142-vx3rgs4r	273	22	131	131	CD
cord-017142-vx3rgs4r	273	23	]	]	-RRB-
cord-017142-vx3rgs4r	273	24	.	.	.
cord-017142-vx3rgs4r	274	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	274	2	is	be	VBZ
cord-017142-vx3rgs4r	274	3	imperative	imperative	JJ
cord-017142-vx3rgs4r	274	4	for	for	IN
cord-017142-vx3rgs4r	274	5	clinicians	clinician	NNS
cord-017142-vx3rgs4r	274	6	to	to	TO
cord-017142-vx3rgs4r	274	7	be	be	VB
cord-017142-vx3rgs4r	274	8	aware	aware	JJ
cord-017142-vx3rgs4r	274	9	of	of	IN
cord-017142-vx3rgs4r	274	10	this	this	DT
cord-017142-vx3rgs4r	274	11	complication	complication	NN
cord-017142-vx3rgs4r	274	12	in	in	IN
cord-017142-vx3rgs4r	274	13	MM	MM	NNP
cord-017142-vx3rgs4r	274	14	patients	patient	NNS
cord-017142-vx3rgs4r	274	15	undergoing	undergo	VBG
cord-017142-vx3rgs4r	274	16	treatment	treatment	NN
cord-017142-vx3rgs4r	274	17	with	with	IN
cord-017142-vx3rgs4r	274	18	novel	novel	JJ
cord-017142-vx3rgs4r	274	19	combinations	combination	NNS
cord-017142-vx3rgs4r	274	20	.	.	.
cord-017142-vx3rgs4r	275	1	TLS	TLS	NNP
cord-017142-vx3rgs4r	275	2	is	be	VBZ
cord-017142-vx3rgs4r	275	3	managed	manage	VBN
cord-017142-vx3rgs4r	275	4	with	with	IN
cord-017142-vx3rgs4r	275	5	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	275	6	intravenous	intravenous	JJ
cord-017142-vx3rgs4r	275	7	hydration	hydration	NN
cord-017142-vx3rgs4r	275	8	,	,	,
cord-017142-vx3rgs4r	275	9	rasburicase	rasburicase	NNP
cord-017142-vx3rgs4r	275	10	,	,	,
cord-017142-vx3rgs4r	275	11	allopurinol	allopurinol	NNP
cord-017142-vx3rgs4r	275	12	,	,	,
cord-017142-vx3rgs4r	275	13	and	and	CC
cord-017142-vx3rgs4r	275	14	at	at	IN
cord-017142-vx3rgs4r	275	15	times	time	NNS
cord-017142-vx3rgs4r	275	16	sodium	sodium	NN
cord-017142-vx3rgs4r	275	17	bicarbonate	bicarbonate	NN
cord-017142-vx3rgs4r	275	18	.	.	.
cord-017142-vx3rgs4r	276	1	Timely	timely	JJ
cord-017142-vx3rgs4r	276	2	initiation	initiation	NN
cord-017142-vx3rgs4r	276	3	of	of	IN
cord-017142-vx3rgs4r	276	4	renal	renal	JJ
cord-017142-vx3rgs4r	276	5	replacement	replacement	NN
cord-017142-vx3rgs4r	276	6	therapy	therapy	NN
cord-017142-vx3rgs4r	276	7	is	be	VBZ
cord-017142-vx3rgs4r	276	8	paramount	paramount	JJ
cord-017142-vx3rgs4r	276	9	in	in	IN
cord-017142-vx3rgs4r	276	10	patients	patient	NNS
cord-017142-vx3rgs4r	276	11	with	with	IN
cord-017142-vx3rgs4r	276	12	lifethreatening	lifethreatening	JJ
cord-017142-vx3rgs4r	276	13	electrolyte	electrolyte	JJ
cord-017142-vx3rgs4r	276	14	disturbances	disturbance	NNS
cord-017142-vx3rgs4r	276	15	.	.	.
cord-017142-vx3rgs4r	277	1	Epidural	epidural	JJ
cord-017142-vx3rgs4r	277	2	spinal	spinal	JJ
cord-017142-vx3rgs4r	277	3	cord	cord	NN
cord-017142-vx3rgs4r	277	4	compression	compression	NN
cord-017142-vx3rgs4r	277	5	(	(	-LRB-
cord-017142-vx3rgs4r	277	6	ESCC	ESCC	NNP
cord-017142-vx3rgs4r	277	7	)	)	-RRB-
cord-017142-vx3rgs4r	277	8	:	:	:
cord-017142-vx3rgs4r	278	1	Acute	acute	JJ
cord-017142-vx3rgs4r	278	2	emergencies	emergency	NNS
cord-017142-vx3rgs4r	278	3	related	relate	VBN
cord-017142-vx3rgs4r	278	4	to	to	IN
cord-017142-vx3rgs4r	278	5	the	the	DT
cord-017142-vx3rgs4r	278	6	nervous	nervous	JJ
cord-017142-vx3rgs4r	278	7	system	system	NN
cord-017142-vx3rgs4r	278	8	in	in	IN
cord-017142-vx3rgs4r	278	9	MM	MM	NNP
cord-017142-vx3rgs4r	278	10	are	be	VBP
cord-017142-vx3rgs4r	278	11	mostly	mostly	RB
cord-017142-vx3rgs4r	278	12	related	related	JJ
cord-017142-vx3rgs4r	278	13	to	to	IN
cord-017142-vx3rgs4r	278	14	ESCC	ESCC	NNP
cord-017142-vx3rgs4r	278	15	.	.	.
cord-017142-vx3rgs4r	279	1	Vertebral	vertebral	JJ
cord-017142-vx3rgs4r	279	2	involvement	involvement	NN
cord-017142-vx3rgs4r	279	3	is	be	VBZ
cord-017142-vx3rgs4r	279	4	prevalent	prevalent	JJ
cord-017142-vx3rgs4r	279	5	in	in	IN
cord-017142-vx3rgs4r	279	6	60	60	CD
cord-017142-vx3rgs4r	279	7	-	-	SYM
cord-017142-vx3rgs4r	279	8	80	80	CD
cord-017142-vx3rgs4r	279	9	%	%	NN
cord-017142-vx3rgs4r	279	10	of	of	IN
cord-017142-vx3rgs4r	279	11	MM	MM	NNP
cord-017142-vx3rgs4r	279	12	patients	patient	NNS
cord-017142-vx3rgs4r	279	13	,	,	,
cord-017142-vx3rgs4r	279	14	and	and	CC
cord-017142-vx3rgs4r	279	15	ESCC	ESCC	NNP
cord-017142-vx3rgs4r	279	16	is	be	VBZ
cord-017142-vx3rgs4r	279	17	encountered	encounter	VBN
cord-017142-vx3rgs4r	279	18	in	in	IN
cord-017142-vx3rgs4r	279	19	approximately	approximately	RB
cord-017142-vx3rgs4r	279	20	10	10	CD
cord-017142-vx3rgs4r	279	21	-	-	SYM
cord-017142-vx3rgs4r	279	22	20	20	CD
cord-017142-vx3rgs4r	279	23	%	%	NN
cord-017142-vx3rgs4r	279	24	of	of	IN
cord-017142-vx3rgs4r	279	25	patients	patient	NNS
cord-017142-vx3rgs4r	279	26	either	either	CC
cord-017142-vx3rgs4r	279	27	at	at	IN
cord-017142-vx3rgs4r	279	28	presentation	presentation	NN
cord-017142-vx3rgs4r	279	29	or	or	CC
cord-017142-vx3rgs4r	279	30	during	during	IN
cord-017142-vx3rgs4r	279	31	the	the	DT
cord-017142-vx3rgs4r	279	32	course	course	NN
cord-017142-vx3rgs4r	279	33	of	of	IN
cord-017142-vx3rgs4r	279	34	disease	disease	NN
cord-017142-vx3rgs4r	279	35	[	[	-LRB-
cord-017142-vx3rgs4r	279	36	64	64	CD
cord-017142-vx3rgs4r	279	37	,	,	,
cord-017142-vx3rgs4r	279	38	130	130	CD
cord-017142-vx3rgs4r	279	39	]	]	-RRB-
cord-017142-vx3rgs4r	279	40	.	.	.
cord-017142-vx3rgs4r	280	1	The	the	DT
cord-017142-vx3rgs4r	280	2	compression	compression	NN
cord-017142-vx3rgs4r	280	3	usually	usually	RB
cord-017142-vx3rgs4r	280	4	results	result	VBZ
cord-017142-vx3rgs4r	280	5	from	from	IN
cord-017142-vx3rgs4r	280	6	vertebral	vertebral	JJ
cord-017142-vx3rgs4r	280	7	fractures	fracture	NNS
cord-017142-vx3rgs4r	280	8	caused	cause	VBN
cord-017142-vx3rgs4r	280	9	by	by	IN
cord-017142-vx3rgs4r	280	10	osteolytic	osteolytic	JJ
cord-017142-vx3rgs4r	280	11	tumors	tumor	NNS
cord-017142-vx3rgs4r	280	12	or	or	CC
cord-017142-vx3rgs4r	280	13	malignant	malignant	JJ
cord-017142-vx3rgs4r	280	14	osteoporosis	osteoporosis	NN
cord-017142-vx3rgs4r	280	15	.	.	.
cord-017142-vx3rgs4r	281	1	Very	very	RB
cord-017142-vx3rgs4r	281	2	rarely	rarely	RB
cord-017142-vx3rgs4r	281	3	,	,	,
cord-017142-vx3rgs4r	281	4	it	-PRON-	PRP
cord-017142-vx3rgs4r	281	5	has	have	VBZ
cord-017142-vx3rgs4r	281	6	been	be	VBN
cord-017142-vx3rgs4r	281	7	reported	report	VBN
cord-017142-vx3rgs4r	281	8	due	due	IN
cord-017142-vx3rgs4r	281	9	to	to	IN
cord-017142-vx3rgs4r	281	10	extraosseous	extraosseous	JJ
cord-017142-vx3rgs4r	281	11	epidural	epidural	NN
cord-017142-vx3rgs4r	281	12	MM	MM	NNP
cord-017142-vx3rgs4r	281	13	or	or	CC
cord-017142-vx3rgs4r	281	14	from	from	IN
cord-017142-vx3rgs4r	281	15	extradural	extradural	NNP
cord-017142-vx3rgs4r	281	16	extension	extension	NN
cord-017142-vx3rgs4r	281	17	of	of	IN
cord-017142-vx3rgs4r	281	18	plasmacytoma	plasmacytoma	NNP
cord-017142-vx3rgs4r	281	19	[	[	-LRB-
cord-017142-vx3rgs4r	281	20	124	124	CD
cord-017142-vx3rgs4r	281	21	]	]	-RRB-
cord-017142-vx3rgs4r	281	22	.	.	.
cord-017142-vx3rgs4r	282	1	In	in	IN
cord-017142-vx3rgs4r	282	2	majority	majority	NN
cord-017142-vx3rgs4r	282	3	of	of	IN
cord-017142-vx3rgs4r	282	4	the	the	DT
cord-017142-vx3rgs4r	282	5	cases	case	NNS
cord-017142-vx3rgs4r	282	6	,	,	,
cord-017142-vx3rgs4r	282	7	thoracic	thoracic	JJ
cord-017142-vx3rgs4r	282	8	or	or	CC
cord-017142-vx3rgs4r	282	9	lumbar	lumbar	JJ
cord-017142-vx3rgs4r	282	10	spinal	spinal	JJ
cord-017142-vx3rgs4r	282	11	cord	cord	NN
cord-017142-vx3rgs4r	282	12	is	be	VBZ
cord-017142-vx3rgs4r	282	13	involved	involve	VBN
cord-017142-vx3rgs4r	282	14	(	(	-LRB-
cord-017142-vx3rgs4r	282	15	>	>	NFP
cord-017142-vx3rgs4r	282	16	80	80	CD
cord-017142-vx3rgs4r	282	17	%	%	NN
cord-017142-vx3rgs4r	282	18	)	)	-RRB-
cord-017142-vx3rgs4r	282	19	[	[	-LRB-
cord-017142-vx3rgs4r	282	20	31	31	CD
cord-017142-vx3rgs4r	282	21	,	,	,
cord-017142-vx3rgs4r	282	22	66	66	CD
cord-017142-vx3rgs4r	282	23	]	]	-RRB-
cord-017142-vx3rgs4r	282	24	.	.	.
cord-017142-vx3rgs4r	283	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	283	2	is	be	VBZ
cord-017142-vx3rgs4r	283	3	vital	vital	JJ
cord-017142-vx3rgs4r	283	4	to	to	TO
cord-017142-vx3rgs4r	283	5	recognize	recognize	VB
cord-017142-vx3rgs4r	283	6	the	the	DT
cord-017142-vx3rgs4r	283	7	symptoms	symptom	NNS
cord-017142-vx3rgs4r	283	8	early	early	RB
cord-017142-vx3rgs4r	283	9	,	,	,
cord-017142-vx3rgs4r	283	10	with	with	IN
cord-017142-vx3rgs4r	283	11	prompt	prompt	JJ
cord-017142-vx3rgs4r	283	12	imaging	imaging	NN
cord-017142-vx3rgs4r	283	13	since	since	IN
cord-017142-vx3rgs4r	283	14	the	the	DT
cord-017142-vx3rgs4r	283	15	strongest	strong	JJS
cord-017142-vx3rgs4r	283	16	predictor	predictor	NN
cord-017142-vx3rgs4r	283	17	of	of	IN
cord-017142-vx3rgs4r	283	18	neurologic	neurologic	JJ
cord-017142-vx3rgs4r	283	19	outcome	outcome	NN
cord-017142-vx3rgs4r	283	20	with	with	IN
cord-017142-vx3rgs4r	283	21	treatment	treatment	NN
cord-017142-vx3rgs4r	283	22	is	be	VBZ
cord-017142-vx3rgs4r	283	23	the	the	DT
cord-017142-vx3rgs4r	283	24	neurologic	neurologic	JJ
cord-017142-vx3rgs4r	283	25	status	status	NN
cord-017142-vx3rgs4r	283	26	when	when	WRB
cord-017142-vx3rgs4r	283	27	treatment	treatment	NN
cord-017142-vx3rgs4r	283	28	is	be	VBZ
cord-017142-vx3rgs4r	283	29	initiated	initiate	VBN
cord-017142-vx3rgs4r	283	30	[	[	-LRB-
cord-017142-vx3rgs4r	283	31	77	77	CD
cord-017142-vx3rgs4r	283	32	]	]	-RRB-
cord-017142-vx3rgs4r	283	33	.	.	.
cord-017142-vx3rgs4r	284	1	Clinical	clinical	JJ
cord-017142-vx3rgs4r	284	2	features	feature	NNS
cord-017142-vx3rgs4r	284	3	depend	depend	VBP
cord-017142-vx3rgs4r	284	4	on	on	IN
cord-017142-vx3rgs4r	284	5	the	the	DT
cord-017142-vx3rgs4r	284	6	site	site	NN
cord-017142-vx3rgs4r	284	7	and	and	CC
cord-017142-vx3rgs4r	284	8	degree	degree	NN
cord-017142-vx3rgs4r	284	9	of	of	IN
cord-017142-vx3rgs4r	284	10	involvement	involvement	NN
cord-017142-vx3rgs4r	284	11	.	.	.
cord-017142-vx3rgs4r	285	1	A	a	DT
cord-017142-vx3rgs4r	285	2	new	new	JJ
cord-017142-vx3rgs4r	285	3	-	-	HYPH
cord-017142-vx3rgs4r	285	4	onset	onset	NN
cord-017142-vx3rgs4r	285	5	back	back	JJ
cord-017142-vx3rgs4r	285	6	pain	pain	NN
cord-017142-vx3rgs4r	285	7	or	or	CC
cord-017142-vx3rgs4r	285	8	a	a	DT
cord-017142-vx3rgs4r	285	9	worsening	worsening	NN
cord-017142-vx3rgs4r	285	10	of	of	IN
cord-017142-vx3rgs4r	285	11	an	an	DT
cord-017142-vx3rgs4r	285	12	existing	exist	VBG
cord-017142-vx3rgs4r	285	13	pain	pain	NN
cord-017142-vx3rgs4r	285	14	in	in	IN
cord-017142-vx3rgs4r	285	15	a	a	DT
cord-017142-vx3rgs4r	285	16	MM	MM	NNP
cord-017142-vx3rgs4r	285	17	patient	patient	NN
cord-017142-vx3rgs4r	285	18	should	should	MD
cord-017142-vx3rgs4r	285	19	prompt	prompt	VB
cord-017142-vx3rgs4r	285	20	a	a	DT
cord-017142-vx3rgs4r	285	21	work	work	NN
cord-017142-vx3rgs4r	285	22	-	-	HYPH
cord-017142-vx3rgs4r	285	23	up	up	NN
cord-017142-vx3rgs4r	285	24	to	to	TO
cord-017142-vx3rgs4r	285	25	rule	rule	VB
cord-017142-vx3rgs4r	285	26	this	this	DT
cord-017142-vx3rgs4r	285	27	out	out	RP
cord-017142-vx3rgs4r	285	28	.	.	.
cord-017142-vx3rgs4r	286	1	Pain	pain	NN
cord-017142-vx3rgs4r	286	2	can	can	MD
cord-017142-vx3rgs4r	286	3	be	be	VB
cord-017142-vx3rgs4r	286	4	localized	localize	VBN
cord-017142-vx3rgs4r	286	5	or	or	CC
cord-017142-vx3rgs4r	286	6	radiating	radiate	VBG
cord-017142-vx3rgs4r	286	7	which	which	WDT
cord-017142-vx3rgs4r	286	8	usually	usually	RB
cord-017142-vx3rgs4r	286	9	worsens	worsen	VBZ
cord-017142-vx3rgs4r	286	10	with	with	IN
cord-017142-vx3rgs4r	286	11	lying	lie	VBG
cord-017142-vx3rgs4r	286	12	down	down	RP
cord-017142-vx3rgs4r	286	13	.	.	.
cord-017142-vx3rgs4r	287	1	Associated	associated	JJ
cord-017142-vx3rgs4r	287	2	bowel	bowel	NN
cord-017142-vx3rgs4r	287	3	and	and	CC
cord-017142-vx3rgs4r	287	4	bladder	bladder	NN
cord-017142-vx3rgs4r	287	5	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	287	6	is	be	VBZ
cord-017142-vx3rgs4r	287	7	present	present	JJ
cord-017142-vx3rgs4r	287	8	in	in	IN
cord-017142-vx3rgs4r	287	9	about	about	IN
cord-017142-vx3rgs4r	287	10	half	half	NN
cord-017142-vx3rgs4r	287	11	of	of	IN
cord-017142-vx3rgs4r	287	12	the	the	DT
cord-017142-vx3rgs4r	287	13	cases	case	NNS
cord-017142-vx3rgs4r	287	14	[	[	-LRB-
cord-017142-vx3rgs4r	287	15	44	44	CD
cord-017142-vx3rgs4r	287	16	]	]	-RRB-
cord-017142-vx3rgs4r	287	17	.	.	.
cord-017142-vx3rgs4r	288	1	If	if	IN
cord-017142-vx3rgs4r	288	2	treatment	treatment	NN
cord-017142-vx3rgs4r	288	3	is	be	VBZ
cord-017142-vx3rgs4r	288	4	delayed	delay	VBN
cord-017142-vx3rgs4r	288	5	,	,	,
cord-017142-vx3rgs4r	288	6	myelopathy	myelopathy	NN
cord-017142-vx3rgs4r	288	7	progresses	progress	VBZ
cord-017142-vx3rgs4r	288	8	to	to	IN
cord-017142-vx3rgs4r	288	9	loss	loss	NN
cord-017142-vx3rgs4r	288	10	of	of	IN
cord-017142-vx3rgs4r	288	11	sensory	sensory	NN
cord-017142-vx3rgs4r	288	12	and	and	CC
cord-017142-vx3rgs4r	288	13	motor	motor	NN
cord-017142-vx3rgs4r	288	14	function	function	NN
cord-017142-vx3rgs4r	288	15	leading	lead	VBG
cord-017142-vx3rgs4r	288	16	to	to	IN
cord-017142-vx3rgs4r	288	17	paraplegia	paraplegia	NN
cord-017142-vx3rgs4r	288	18	.	.	.
cord-017142-vx3rgs4r	289	1	Spinal	spinal	JJ
cord-017142-vx3rgs4r	289	2	cord	cord	NN
cord-017142-vx3rgs4r	289	3	injury	injury	NN
cord-017142-vx3rgs4r	289	4	at	at	IN
cord-017142-vx3rgs4r	289	5	the	the	DT
cord-017142-vx3rgs4r	289	6	cervical	cervical	JJ
cord-017142-vx3rgs4r	289	7	level	level	NN
cord-017142-vx3rgs4r	289	8	is	be	VBZ
cord-017142-vx3rgs4r	289	9	uncommon	uncommon	JJ
cord-017142-vx3rgs4r	289	10	;	;	:
cord-017142-vx3rgs4r	289	11	however	however	RB
cord-017142-vx3rgs4r	289	12	,	,	,
cord-017142-vx3rgs4r	289	13	if	if	IN
cord-017142-vx3rgs4r	289	14	affected	affect	VBN
cord-017142-vx3rgs4r	289	15	above	above	IN
cord-017142-vx3rgs4r	289	16	C4-C5	C4-C5	NNP
cord-017142-vx3rgs4r	289	17	,	,	,
cord-017142-vx3rgs4r	289	18	it	-PRON-	PRP
cord-017142-vx3rgs4r	289	19	results	result	VBZ
cord-017142-vx3rgs4r	289	20	in	in	IN
cord-017142-vx3rgs4r	289	21	respiratory	respiratory	JJ
cord-017142-vx3rgs4r	289	22	,	,	,
cord-017142-vx3rgs4r	289	23	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	289	24	,	,	,
cord-017142-vx3rgs4r	289	25	and	and	CC
cord-017142-vx3rgs4r	289	26	autonomic	autonomic	JJ
cord-017142-vx3rgs4r	289	27	decompensation	decompensation	NN
cord-017142-vx3rgs4r	289	28	[	[	-LRB-
cord-017142-vx3rgs4r	289	29	86	86	CD
cord-017142-vx3rgs4r	289	30	]	]	-RRB-
cord-017142-vx3rgs4r	289	31	.	.	.
cord-017142-vx3rgs4r	290	1	Gadolinium	gadolinium	NN
cord-017142-vx3rgs4r	290	2	-	-	HYPH
cord-017142-vx3rgs4r	290	3	enhanced	enhance	VBN
cord-017142-vx3rgs4r	290	4	MRI	MRI	NNP
cord-017142-vx3rgs4r	290	5	is	be	VBZ
cord-017142-vx3rgs4r	290	6	the	the	DT
cord-017142-vx3rgs4r	290	7	initial	initial	JJ
cord-017142-vx3rgs4r	290	8	gold	gold	NN
cord-017142-vx3rgs4r	290	9	standard	standard	JJ
cord-017142-vx3rgs4r	290	10	imaging	imaging	NN
cord-017142-vx3rgs4r	290	11	modality	modality	NN
cord-017142-vx3rgs4r	290	12	as	as	IN
cord-017142-vx3rgs4r	290	13	it	-PRON-	PRP
cord-017142-vx3rgs4r	290	14	can	can	MD
cord-017142-vx3rgs4r	290	15	aid	aid	VB
cord-017142-vx3rgs4r	290	16	in	in	IN
cord-017142-vx3rgs4r	290	17	the	the	DT
cord-017142-vx3rgs4r	290	18	thorough	thorough	JJ
cord-017142-vx3rgs4r	290	19	evaluation	evaluation	NN
cord-017142-vx3rgs4r	290	20	of	of	IN
cord-017142-vx3rgs4r	290	21	spine	spine	NN
cord-017142-vx3rgs4r	290	22	,	,	,
cord-017142-vx3rgs4r	290	23	degree	degree	NN
cord-017142-vx3rgs4r	290	24	of	of	IN
cord-017142-vx3rgs4r	290	25	tumor	tumor	NN
cord-017142-vx3rgs4r	290	26	or	or	CC
cord-017142-vx3rgs4r	290	27	fracture	fracture	NN
cord-017142-vx3rgs4r	290	28	involvement	involvement	NN
cord-017142-vx3rgs4r	290	29	,	,	,
cord-017142-vx3rgs4r	290	30	and	and	CC
cord-017142-vx3rgs4r	290	31	for	for	IN
cord-017142-vx3rgs4r	290	32	radiation	radiation	NN
cord-017142-vx3rgs4r	290	33	planning	planning	NN
cord-017142-vx3rgs4r	290	34	[	[	-LRB-
cord-017142-vx3rgs4r	290	35	59	59	CD
cord-017142-vx3rgs4r	290	36	]	]	-RRB-
cord-017142-vx3rgs4r	290	37	.	.	.
cord-017142-vx3rgs4r	291	1	The	the	DT
cord-017142-vx3rgs4r	291	2	safety	safety	NN
cord-017142-vx3rgs4r	291	3	of	of	IN
cord-017142-vx3rgs4r	291	4	MRI	MRI	NNP
cord-017142-vx3rgs4r	291	5	should	should	MD
cord-017142-vx3rgs4r	291	6	be	be	VB
cord-017142-vx3rgs4r	291	7	discussed	discuss	VBN
cord-017142-vx3rgs4r	291	8	in	in	IN
cord-017142-vx3rgs4r	291	9	the	the	DT
cord-017142-vx3rgs4r	291	10	presence	presence	NN
cord-017142-vx3rgs4r	291	11	of	of	IN
cord-017142-vx3rgs4r	291	12	pacemakers	pacemaker	NNS
cord-017142-vx3rgs4r	291	13	and	and	CC
cord-017142-vx3rgs4r	291	14	defibrillators	defibrillator	NNS
cord-017142-vx3rgs4r	291	15	in	in	IN
cord-017142-vx3rgs4r	291	16	a	a	DT
cord-017142-vx3rgs4r	291	17	multidisciplinary	multidisciplinary	JJ
cord-017142-vx3rgs4r	291	18	fashion	fashion	NN
cord-017142-vx3rgs4r	291	19	,	,	,
cord-017142-vx3rgs4r	291	20	and	and	CC
cord-017142-vx3rgs4r	291	21	if	if	IN
cord-017142-vx3rgs4r	291	22	contraindicated	contraindicate	VBN
cord-017142-vx3rgs4r	291	23	,	,	,
cord-017142-vx3rgs4r	291	24	CT	CT	NNP
cord-017142-vx3rgs4r	291	25	myelography	myelography	NN
cord-017142-vx3rgs4r	291	26	should	should	MD
cord-017142-vx3rgs4r	291	27	be	be	VB
cord-017142-vx3rgs4r	291	28	performed	perform	VBN
cord-017142-vx3rgs4r	291	29	.	.	.
cord-017142-vx3rgs4r	292	1	There	there	EX
cord-017142-vx3rgs4r	292	2	is	be	VBZ
cord-017142-vx3rgs4r	292	3	a	a	DT
cord-017142-vx3rgs4r	292	4	lack	lack	NN
cord-017142-vx3rgs4r	292	5	of	of	IN
cord-017142-vx3rgs4r	292	6	consensus	consensus	NN
cord-017142-vx3rgs4r	292	7	guidelines	guideline	NNS
cord-017142-vx3rgs4r	292	8	for	for	IN
cord-017142-vx3rgs4r	292	9	treatment	treatment	NN
cord-017142-vx3rgs4r	292	10	and	and	CC
cord-017142-vx3rgs4r	292	11	hence	hence	RB
cord-017142-vx3rgs4r	292	12	warrants	warrant	VBZ
cord-017142-vx3rgs4r	292	13	an	an	DT
cord-017142-vx3rgs4r	292	14	emergent	emergent	JJ
cord-017142-vx3rgs4r	292	15	multidisciplinary	multidisciplinary	JJ
cord-017142-vx3rgs4r	292	16	team	team	NN
cord-017142-vx3rgs4r	292	17	consult	consult	VBP
cord-017142-vx3rgs4r	292	18	involving	involve	VBG
cord-017142-vx3rgs4r	292	19	the	the	DT
cord-017142-vx3rgs4r	292	20	oncologist	oncologist	NN
cord-017142-vx3rgs4r	292	21	,	,	,
cord-017142-vx3rgs4r	292	22	neurosurgeon	neurosurgeon	NN
cord-017142-vx3rgs4r	292	23	,	,	,
cord-017142-vx3rgs4r	292	24	and	and	CC
cord-017142-vx3rgs4r	292	25	radiation	radiation	NN
cord-017142-vx3rgs4r	292	26	oncologist	oncologist	NN
cord-017142-vx3rgs4r	292	27	.	.	.
cord-017142-vx3rgs4r	293	1	The	the	DT
cord-017142-vx3rgs4r	293	2	optimal	optimal	JJ
cord-017142-vx3rgs4r	293	3	management	management	NN
cord-017142-vx3rgs4r	293	4	depends	depend	VBZ
cord-017142-vx3rgs4r	293	5	on	on	IN
cord-017142-vx3rgs4r	293	6	the	the	DT
cord-017142-vx3rgs4r	293	7	extent	extent	NN
cord-017142-vx3rgs4r	293	8	of	of	IN
cord-017142-vx3rgs4r	293	9	disease	disease	NN
cord-017142-vx3rgs4r	293	10	,	,	,
cord-017142-vx3rgs4r	293	11	performance	performance	NN
cord-017142-vx3rgs4r	293	12	status	status	NN
cord-017142-vx3rgs4r	293	13	of	of	IN
cord-017142-vx3rgs4r	293	14	the	the	DT
cord-017142-vx3rgs4r	293	15	patient	patient	NN
cord-017142-vx3rgs4r	293	16	,	,	,
cord-017142-vx3rgs4r	293	17	and	and	CC
cord-017142-vx3rgs4r	293	18	presence	presence	NN
cord-017142-vx3rgs4r	293	19	of	of	IN
cord-017142-vx3rgs4r	293	20	spine	spine	NN
cord-017142-vx3rgs4r	293	21	instability	instability	NN
cord-017142-vx3rgs4r	293	22	.	.	.
cord-017142-vx3rgs4r	294	1	Immediate	immediate	JJ
cord-017142-vx3rgs4r	294	2	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	294	3	strategies	strategy	NNS
cord-017142-vx3rgs4r	294	4	involve	involve	VBP
cord-017142-vx3rgs4r	294	5	achieving	achieve	VBG
cord-017142-vx3rgs4r	294	6	minimal	minimal	JJ
cord-017142-vx3rgs4r	294	7	mobility	mobility	NN
cord-017142-vx3rgs4r	294	8	until	until	IN
cord-017142-vx3rgs4r	294	9	stability	stability	NN
cord-017142-vx3rgs4r	294	10	of	of	IN
cord-017142-vx3rgs4r	294	11	the	the	DT
cord-017142-vx3rgs4r	294	12	spine	spine	NN
cord-017142-vx3rgs4r	294	13	is	be	VBZ
cord-017142-vx3rgs4r	294	14	achieved	achieve	VBN
cord-017142-vx3rgs4r	294	15	.	.	.
cord-017142-vx3rgs4r	295	1	Steroids	steroid	NNS
cord-017142-vx3rgs4r	295	2	should	should	MD
cord-017142-vx3rgs4r	295	3	be	be	VB
cord-017142-vx3rgs4r	295	4	initiated	initiate	VBN
cord-017142-vx3rgs4r	295	5	even	even	RB
cord-017142-vx3rgs4r	295	6	while	while	IN
cord-017142-vx3rgs4r	295	7	awaiting	await	VBG
cord-017142-vx3rgs4r	295	8	diagnostic	diagnostic	JJ
cord-017142-vx3rgs4r	295	9	study	study	NN
cord-017142-vx3rgs4r	295	10	results	result	NNS
cord-017142-vx3rgs4r	295	11	(	(	-LRB-
cord-017142-vx3rgs4r	295	12	dexamethasone	dexamethasone	NN
cord-017142-vx3rgs4r	295	13	at	at	IN
cord-017142-vx3rgs4r	295	14	doses	dose	NNS
cord-017142-vx3rgs4r	296	1	10	10	CD
cord-017142-vx3rgs4r	296	2	mg	mg	NNP
cord-017142-vx3rgs4r	296	3	IV	IV	NNP
cord-017142-vx3rgs4r	296	4	followed	follow	VBN
cord-017142-vx3rgs4r	296	5	by	by	IN
cord-017142-vx3rgs4r	296	6	16	16	CD
cord-017142-vx3rgs4r	296	7	mg	mg	NNP
cord-017142-vx3rgs4r	296	8	daily	daily	RB
cord-017142-vx3rgs4r	296	9	in	in	IN
cord-017142-vx3rgs4r	296	10	divided	divide	VBN
cord-017142-vx3rgs4r	296	11	doses	dose	NNS
cord-017142-vx3rgs4r	296	12	with	with	IN
cord-017142-vx3rgs4r	296	13	a	a	DT
cord-017142-vx3rgs4r	296	14	taper	taper	NN
cord-017142-vx3rgs4r	296	15	over	over	IN
cord-017142-vx3rgs4r	296	16	2	2	CD
cord-017142-vx3rgs4r	296	17	weeks	week	NNS
cord-017142-vx3rgs4r	296	18	)	)	-RRB-
cord-017142-vx3rgs4r	297	1	[	[	-LRB-
cord-017142-vx3rgs4r	297	2	137	137	CD
cord-017142-vx3rgs4r	297	3	]	]	-RRB-
cord-017142-vx3rgs4r	297	4	.	.	.
cord-017142-vx3rgs4r	298	1	Doses	dose	NNS
cord-017142-vx3rgs4r	298	2	as	as	RB
cord-017142-vx3rgs4r	298	3	high	high	JJ
cord-017142-vx3rgs4r	298	4	as	as	IN
cord-017142-vx3rgs4r	298	5	100	100	CD
cord-017142-vx3rgs4r	298	6	mg	mg	NNP
cord-017142-vx3rgs4r	298	7	initial	initial	JJ
cord-017142-vx3rgs4r	298	8	bolus	bolus	NN
cord-017142-vx3rgs4r	298	9	were	be	VBD
cord-017142-vx3rgs4r	298	10	used	use	VBN
cord-017142-vx3rgs4r	298	11	in	in	IN
cord-017142-vx3rgs4r	298	12	the	the	DT
cord-017142-vx3rgs4r	298	13	past	past	NN
cord-017142-vx3rgs4r	298	14	,	,	,
cord-017142-vx3rgs4r	298	15	but	but	CC
cord-017142-vx3rgs4r	298	16	are	be	VBP
cord-017142-vx3rgs4r	298	17	not	not	RB
cord-017142-vx3rgs4r	298	18	used	use	VBN
cord-017142-vx3rgs4r	298	19	any	any	DT
cord-017142-vx3rgs4r	298	20	more	more	RBR
cord-017142-vx3rgs4r	298	21	due	due	JJ
cord-017142-vx3rgs4r	298	22	to	to	IN
cord-017142-vx3rgs4r	298	23	risk	risk	NN
cord-017142-vx3rgs4r	298	24	of	of	IN
cord-017142-vx3rgs4r	298	25	significant	significant	JJ
cord-017142-vx3rgs4r	298	26	side	side	NN
cord-017142-vx3rgs4r	298	27	effects	effect	NNS
cord-017142-vx3rgs4r	298	28	and	and	CC
cord-017142-vx3rgs4r	298	29	limited	limited	JJ
cord-017142-vx3rgs4r	298	30	evidence	evidence	NN
cord-017142-vx3rgs4r	298	31	to	to	TO
cord-017142-vx3rgs4r	298	32	suggest	suggest	VB
cord-017142-vx3rgs4r	298	33	benefit	benefit	VB
cord-017142-vx3rgs4r	298	34	[	[	-LRB-
cord-017142-vx3rgs4r	298	35	45	45	CD
cord-017142-vx3rgs4r	298	36	]	]	-RRB-
cord-017142-vx3rgs4r	298	37	.	.	.
cord-017142-vx3rgs4r	299	1	Spine	spine	NN
cord-017142-vx3rgs4r	299	2	stabilization	stabilization	NN
cord-017142-vx3rgs4r	299	3	by	by	IN
cord-017142-vx3rgs4r	299	4	reducing	reduce	VBG
cord-017142-vx3rgs4r	299	5	the	the	DT
cord-017142-vx3rgs4r	299	6	mechanical	mechanical	JJ
cord-017142-vx3rgs4r	299	7	load	load	NN
cord-017142-vx3rgs4r	299	8	can	can	MD
cord-017142-vx3rgs4r	299	9	be	be	VB
cord-017142-vx3rgs4r	299	10	achieved	achieve	VBN
cord-017142-vx3rgs4r	299	11	with	with	IN
cord-017142-vx3rgs4r	299	12	the	the	DT
cord-017142-vx3rgs4r	299	13	use	use	NN
cord-017142-vx3rgs4r	299	14	of	of	IN
cord-017142-vx3rgs4r	299	15	a	a	DT
cord-017142-vx3rgs4r	299	16	neck	neck	NN
cord-017142-vx3rgs4r	299	17	collar	collar	NN
cord-017142-vx3rgs4r	299	18	(	(	-LRB-
cord-017142-vx3rgs4r	299	19	e.g.	e.g.	RB
cord-017142-vx3rgs4r	299	20	,	,	,
cord-017142-vx3rgs4r	299	21	Philadelphia	Philadelphia	NNP
cord-017142-vx3rgs4r	299	22	collar	collar	NN
cord-017142-vx3rgs4r	299	23	)	)	-RRB-
cord-017142-vx3rgs4r	299	24	in	in	IN
cord-017142-vx3rgs4r	299	25	case	case	NN
cord-017142-vx3rgs4r	299	26	of	of	IN
cord-017142-vx3rgs4r	299	27	cervical	cervical	JJ
cord-017142-vx3rgs4r	299	28	spine	spine	NN
cord-017142-vx3rgs4r	299	29	or	or	CC
cord-017142-vx3rgs4r	299	30	braces	brace	NNS
cord-017142-vx3rgs4r	299	31	at	at	IN
cord-017142-vx3rgs4r	299	32	other	other	JJ
cord-017142-vx3rgs4r	299	33	sites	site	NNS
cord-017142-vx3rgs4r	299	34	and	and	CC
cord-017142-vx3rgs4r	299	35	is	be	VBZ
cord-017142-vx3rgs4r	299	36	not	not	RB
cord-017142-vx3rgs4r	299	37	generally	generally	RB
cord-017142-vx3rgs4r	299	38	recommended	recommend	VBN
cord-017142-vx3rgs4r	299	39	for	for	IN
cord-017142-vx3rgs4r	299	40	longer	long	JJR
cord-017142-vx3rgs4r	299	41	than	than	IN
cord-017142-vx3rgs4r	299	42	3	3	CD
cord-017142-vx3rgs4r	299	43	months	month	NNS
cord-017142-vx3rgs4r	299	44	[	[	-LRB-
cord-017142-vx3rgs4r	299	45	87	87	CD
cord-017142-vx3rgs4r	299	46	]	]	-RRB-
cord-017142-vx3rgs4r	299	47	.	.	.
cord-017142-vx3rgs4r	300	1	A	a	DT
cord-017142-vx3rgs4r	300	2	thorough	thorough	JJ
cord-017142-vx3rgs4r	300	3	baseline	baseline	JJ
cord-017142-vx3rgs4r	300	4	neurological	neurological	JJ
cord-017142-vx3rgs4r	300	5	exam	exam	NN
cord-017142-vx3rgs4r	300	6	followed	follow	VBN
cord-017142-vx3rgs4r	300	7	by	by	IN
cord-017142-vx3rgs4r	300	8	serial	serial	JJ
cord-017142-vx3rgs4r	300	9	neurological	neurological	JJ
cord-017142-vx3rgs4r	300	10	exams	exam	NNS
cord-017142-vx3rgs4r	300	11	should	should	MD
cord-017142-vx3rgs4r	300	12	be	be	VB
cord-017142-vx3rgs4r	300	13	done	do	VBN
cord-017142-vx3rgs4r	300	14	to	to	TO
cord-017142-vx3rgs4r	300	15	assess	assess	VB
cord-017142-vx3rgs4r	300	16	clinical	clinical	JJ
cord-017142-vx3rgs4r	300	17	status	status	NN
cord-017142-vx3rgs4r	300	18	.	.	.
cord-017142-vx3rgs4r	301	1	Radiotherapy	radiotherapy	NN
cord-017142-vx3rgs4r	301	2	should	should	MD
cord-017142-vx3rgs4r	301	3	be	be	VB
cord-017142-vx3rgs4r	301	4	started	start	VBN
cord-017142-vx3rgs4r	301	5	as	as	RB
cord-017142-vx3rgs4r	301	6	soon	soon	RB
cord-017142-vx3rgs4r	301	7	as	as	IN
cord-017142-vx3rgs4r	301	8	possible	possible	JJ
cord-017142-vx3rgs4r	301	9	as	as	IN
cord-017142-vx3rgs4r	301	10	MM	MM	NNP
cord-017142-vx3rgs4r	301	11	is	be	VBZ
cord-017142-vx3rgs4r	301	12	extremely	extremely	RB
cord-017142-vx3rgs4r	301	13	radiosensitive	radiosensitive	JJ
cord-017142-vx3rgs4r	301	14	,	,	,
cord-017142-vx3rgs4r	301	15	unless	unless	IN
cord-017142-vx3rgs4r	301	16	in	in	IN
cord-017142-vx3rgs4r	301	17	very	very	RB
cord-017142-vx3rgs4r	301	18	late	late	RB
cord-017142-vx3rgs4r	301	19	in	in	IN
cord-017142-vx3rgs4r	301	20	the	the	DT
cord-017142-vx3rgs4r	301	21	disease	disease	NN
cord-017142-vx3rgs4r	301	22	.	.	.
cord-017142-vx3rgs4r	302	1	In	in	IN
cord-017142-vx3rgs4r	302	2	a	a	DT
cord-017142-vx3rgs4r	302	3	retrospective	retrospective	JJ
cord-017142-vx3rgs4r	302	4	study	study	NN
cord-017142-vx3rgs4r	302	5	which	which	WDT
cord-017142-vx3rgs4r	302	6	included	include	VBD
cord-017142-vx3rgs4r	302	7	63	63	CD
cord-017142-vx3rgs4r	302	8	patients	patient	NNS
cord-017142-vx3rgs4r	302	9	with	with	IN
cord-017142-vx3rgs4r	302	10	MM	MM	NNP
cord-017142-vx3rgs4r	302	11	/	/	SYM
cord-017142-vx3rgs4r	302	12	lymphoma	lymphoma	NN
cord-017142-vx3rgs4r	302	13	treated	treat	VBN
cord-017142-vx3rgs4r	302	14	with	with	IN
cord-017142-vx3rgs4r	302	15	RT	RT	NNP
cord-017142-vx3rgs4r	302	16	alone	alone	RB
cord-017142-vx3rgs4r	302	17	,	,	,
cord-017142-vx3rgs4r	302	18	76	76	CD
cord-017142-vx3rgs4r	302	19	%	%	NN
cord-017142-vx3rgs4r	302	20	of	of	IN
cord-017142-vx3rgs4r	302	21	the	the	DT
cord-017142-vx3rgs4r	302	22	patients	patient	NNS
cord-017142-vx3rgs4r	302	23	experienced	experience	VBD
cord-017142-vx3rgs4r	302	24	an	an	DT
cord-017142-vx3rgs4r	302	25	improvement	improvement	NN
cord-017142-vx3rgs4r	302	26	in	in	IN
cord-017142-vx3rgs4r	302	27	motor	motor	NN
cord-017142-vx3rgs4r	302	28	function	function	NN
cord-017142-vx3rgs4r	302	29	,	,	,
cord-017142-vx3rgs4r	302	30	22	22	CD
cord-017142-vx3rgs4r	302	31	%	%	NN
cord-017142-vx3rgs4r	302	32	had	have	VBD
cord-017142-vx3rgs4r	302	33	no	no	DT
cord-017142-vx3rgs4r	302	34	change	change	NN
cord-017142-vx3rgs4r	302	35	,	,	,
cord-017142-vx3rgs4r	302	36	while	while	IN
cord-017142-vx3rgs4r	302	37	2	2	CD
cord-017142-vx3rgs4r	302	38	%	%	NN
cord-017142-vx3rgs4r	302	39	deteriorated	deteriorate	VBD
cord-017142-vx3rgs4r	302	40	.	.	.
cord-017142-vx3rgs4r	303	1	In	in	IN
cord-017142-vx3rgs4r	303	2	this	this	DT
cord-017142-vx3rgs4r	303	3	group	group	NN
cord-017142-vx3rgs4r	303	4	,	,	,
cord-017142-vx3rgs4r	303	5	patients	patient	NNS
cord-017142-vx3rgs4r	303	6	who	who	WP
cord-017142-vx3rgs4r	303	7	experienced	experience	VBD
cord-017142-vx3rgs4r	303	8	slowly	slowly	RB
cord-017142-vx3rgs4r	303	9	progressive	progressive	JJ
cord-017142-vx3rgs4r	303	10	motor	motor	NN
cord-017142-vx3rgs4r	303	11	deficit	deficit	NN
cord-017142-vx3rgs4r	303	12	defined	define	VBN
cord-017142-vx3rgs4r	303	13	as	as	IN
cord-017142-vx3rgs4r	303	14	time	time	NN
cord-017142-vx3rgs4r	303	15	of	of	IN
cord-017142-vx3rgs4r	303	16	onset	onset	NN
cord-017142-vx3rgs4r	303	17	>	>	XX
cord-017142-vx3rgs4r	303	18	14	14	CD
cord-017142-vx3rgs4r	303	19	days	day	NNS
cord-017142-vx3rgs4r	303	20	had	have	VBD
cord-017142-vx3rgs4r	303	21	better	well	JJR
cord-017142-vx3rgs4r	303	22	response	response	NN
cord-017142-vx3rgs4r	303	23	rates	rate	NNS
cord-017142-vx3rgs4r	303	24	than	than	IN
cord-017142-vx3rgs4r	303	25	patients	patient	NNS
cord-017142-vx3rgs4r	303	26	who	who	WP
cord-017142-vx3rgs4r	303	27	had	have	VBD
cord-017142-vx3rgs4r	303	28	fast	fast	JJ
cord-017142-vx3rgs4r	303	29	onset	onset	NN
cord-017142-vx3rgs4r	303	30	deficit	deficit	NN
cord-017142-vx3rgs4r	303	31	defined	define	VBN
cord-017142-vx3rgs4r	303	32	as	as	IN
cord-017142-vx3rgs4r	303	33	time	time	NN
cord-017142-vx3rgs4r	303	34	of	of	IN
cord-017142-vx3rgs4r	303	35	onset	onset	NN
cord-017142-vx3rgs4r	303	36	<	<	XX
cord-017142-vx3rgs4r	303	37	14	14	CD
cord-017142-vx3rgs4r	303	38	days	day	NNS
cord-017142-vx3rgs4r	303	39	.	.	.
cord-017142-vx3rgs4r	304	1	The	the	DT
cord-017142-vx3rgs4r	304	2	improvements	improvement	NNS
cord-017142-vx3rgs4r	304	3	in	in	IN
cord-017142-vx3rgs4r	304	4	motor	motor	NN
cord-017142-vx3rgs4r	304	5	function	function	NN
cord-017142-vx3rgs4r	304	6	in	in	IN
cord-017142-vx3rgs4r	304	7	these	these	DT
cord-017142-vx3rgs4r	304	8	groups	group	NNS
cord-017142-vx3rgs4r	304	9	were	be	VBD
cord-017142-vx3rgs4r	304	10	80	80	CD
cord-017142-vx3rgs4r	304	11	%	%	NN
cord-017142-vx3rgs4r	304	12	and	and	CC
cord-017142-vx3rgs4r	304	13	70	70	CD
cord-017142-vx3rgs4r	304	14	%	%	NN
cord-017142-vx3rgs4r	304	15	,	,	,
cord-017142-vx3rgs4r	304	16	respectively	respectively	RB
cord-017142-vx3rgs4r	304	17	.	.	.
cord-017142-vx3rgs4r	305	1	No	no	DT
cord-017142-vx3rgs4r	305	2	patients	patient	NNS
cord-017142-vx3rgs4r	305	3	who	who	WP
cord-017142-vx3rgs4r	305	4	received	receive	VBD
cord-017142-vx3rgs4r	305	5	radiotherapy	radiotherapy	NN
cord-017142-vx3rgs4r	305	6	progressed	progress	VBD
cord-017142-vx3rgs4r	305	7	in	in	IN
cord-017142-vx3rgs4r	305	8	the	the	DT
cord-017142-vx3rgs4r	305	9	slow	slow	JJ
cord-017142-vx3rgs4r	305	10	onset	onset	NN
cord-017142-vx3rgs4r	305	11	motor	motor	NN
cord-017142-vx3rgs4r	305	12	weakness	weakness	NN
cord-017142-vx3rgs4r	305	13	group	group	NN
cord-017142-vx3rgs4r	305	14	[	[	-LRB-
cord-017142-vx3rgs4r	305	15	103	103	CD
cord-017142-vx3rgs4r	305	16	,	,	,
cord-017142-vx3rgs4r	305	17	104	104	CD
cord-017142-vx3rgs4r	305	18	]	]	-RRB-
cord-017142-vx3rgs4r	305	19	.	.	.
cord-017142-vx3rgs4r	306	1	Current	current	JJ
cord-017142-vx3rgs4r	306	2	evidence	evidence	NN
cord-017142-vx3rgs4r	306	3	does	do	VBZ
cord-017142-vx3rgs4r	306	4	not	not	RB
cord-017142-vx3rgs4r	306	5	support	support	VB
cord-017142-vx3rgs4r	306	6	resorting	resort	VBG
cord-017142-vx3rgs4r	306	7	to	to	IN
cord-017142-vx3rgs4r	306	8	surgery	surgery	NN
cord-017142-vx3rgs4r	306	9	in	in	IN
cord-017142-vx3rgs4r	306	10	patients	patient	NNS
cord-017142-vx3rgs4r	306	11	with	with	IN
cord-017142-vx3rgs4r	306	12	ESCC	ESCC	NNP
cord-017142-vx3rgs4r	306	13	,	,	,
cord-017142-vx3rgs4r	306	14	as	as	IN
cord-017142-vx3rgs4r	306	15	most	most	JJS
cord-017142-vx3rgs4r	306	16	MM	MM	NNP
cord-017142-vx3rgs4r	306	17	cases	case	NNS
cord-017142-vx3rgs4r	306	18	respond	respond	VBP
cord-017142-vx3rgs4r	306	19	to	to	IN
cord-017142-vx3rgs4r	306	20	radiation	radiation	NN
cord-017142-vx3rgs4r	306	21	.	.	.
cord-017142-vx3rgs4r	307	1	The	the	DT
cord-017142-vx3rgs4r	307	2	need	need	NN
cord-017142-vx3rgs4r	307	3	for	for	IN
cord-017142-vx3rgs4r	307	4	surgical	surgical	JJ
cord-017142-vx3rgs4r	307	5	stabilization	stabilization	NN
cord-017142-vx3rgs4r	307	6	with	with	IN
cord-017142-vx3rgs4r	307	7	fixation	fixation	NN
cord-017142-vx3rgs4r	307	8	or	or	CC
cord-017142-vx3rgs4r	307	9	by	by	IN
cord-017142-vx3rgs4r	307	10	percutaneous	percutaneous	JJ
cord-017142-vx3rgs4r	307	11	repair	repair	NN
cord-017142-vx3rgs4r	307	12	is	be	VBZ
cord-017142-vx3rgs4r	307	13	in	in	IN
cord-017142-vx3rgs4r	307	14	general	general	JJ
cord-017142-vx3rgs4r	307	15	reserved	reserve	VBN
cord-017142-vx3rgs4r	307	16	for	for	IN
cord-017142-vx3rgs4r	307	17	cases	case	NNS
cord-017142-vx3rgs4r	307	18	with	with	IN
cord-017142-vx3rgs4r	307	19	spine	spine	NN
cord-017142-vx3rgs4r	307	20	instability	instability	NN
cord-017142-vx3rgs4r	307	21	or	or	CC
cord-017142-vx3rgs4r	307	22	spine	spine	NN
cord-017142-vx3rgs4r	307	23	compression	compression	NN
cord-017142-vx3rgs4r	307	24	from	from	IN
cord-017142-vx3rgs4r	307	25	a	a	DT
cord-017142-vx3rgs4r	307	26	vertebral	vertebral	JJ
cord-017142-vx3rgs4r	307	27	body	body	NN
cord-017142-vx3rgs4r	307	28	.	.	.
cord-017142-vx3rgs4r	308	1	Treatment	treatment	NN
cord-017142-vx3rgs4r	308	2	of	of	IN
cord-017142-vx3rgs4r	308	3	the	the	DT
cord-017142-vx3rgs4r	308	4	underlying	underlying	JJ
cord-017142-vx3rgs4r	308	5	malignancy	malignancy	NN
cord-017142-vx3rgs4r	308	6	with	with	IN
cord-017142-vx3rgs4r	308	7	systemic	systemic	JJ
cord-017142-vx3rgs4r	308	8	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	308	9	or	or	CC
cord-017142-vx3rgs4r	308	10	novel	novel	JJ
cord-017142-vx3rgs4r	308	11	agents	agent	NNS
cord-017142-vx3rgs4r	308	12	,	,	,
cord-017142-vx3rgs4r	308	13	bone	bone	NN
cord-017142-vx3rgs4r	308	14	-	-	HYPH
cord-017142-vx3rgs4r	308	15	modifying	modify	VBG
cord-017142-vx3rgs4r	308	16	agents	agent	NNS
cord-017142-vx3rgs4r	308	17	,	,	,
cord-017142-vx3rgs4r	308	18	and	and	CC
cord-017142-vx3rgs4r	308	19	neurorehabilitation	neurorehabilitation	NNP
cord-017142-vx3rgs4r	308	20	can	can	MD
cord-017142-vx3rgs4r	308	21	help	help	VB
cord-017142-vx3rgs4r	308	22	in	in	IN
cord-017142-vx3rgs4r	308	23	recovery	recovery	NN
cord-017142-vx3rgs4r	308	24	of	of	IN
cord-017142-vx3rgs4r	308	25	the	the	DT
cord-017142-vx3rgs4r	308	26	vertebral	vertebral	JJ
cord-017142-vx3rgs4r	308	27	and	and	CC
cord-017142-vx3rgs4r	308	28	spinal	spinal	JJ
cord-017142-vx3rgs4r	308	29	damage	damage	NN
cord-017142-vx3rgs4r	308	30	[	[	-LRB-
cord-017142-vx3rgs4r	308	31	72	72	CD
cord-017142-vx3rgs4r	308	32	,	,	,
cord-017142-vx3rgs4r	308	33	101	101	CD
cord-017142-vx3rgs4r	308	34	]	]	-RRB-
cord-017142-vx3rgs4r	308	35	.	.	.
cord-017142-vx3rgs4r	309	1	CNS	CNS	NNP
cord-017142-vx3rgs4r	309	2	myelomatosis	myelomatosis	NNP
cord-017142-vx3rgs4r	309	3	:	:	:
cord-017142-vx3rgs4r	310	1	Neurological	neurological	JJ
cord-017142-vx3rgs4r	310	2	symptoms	symptom	NNS
cord-017142-vx3rgs4r	310	3	in	in	IN
cord-017142-vx3rgs4r	310	4	MM	MM	NNP
cord-017142-vx3rgs4r	310	5	are	be	VBP
cord-017142-vx3rgs4r	310	6	most	most	RBS
cord-017142-vx3rgs4r	310	7	commonly	commonly	RB
cord-017142-vx3rgs4r	310	8	due	due	JJ
cord-017142-vx3rgs4r	310	9	to	to	IN
cord-017142-vx3rgs4r	310	10	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	310	11	,	,	,
cord-017142-vx3rgs4r	310	12	cord	cord	NN
cord-017142-vx3rgs4r	310	13	compression	compression	NN
cord-017142-vx3rgs4r	310	14	,	,	,
cord-017142-vx3rgs4r	310	15	anti	anti	JJ
cord-017142-vx3rgs4r	310	16	-	-	JJ
cord-017142-vx3rgs4r	310	17	MM	mm	JJ
cord-017142-vx3rgs4r	310	18	drug	drug	NN
cord-017142-vx3rgs4r	310	19	related	relate	VBN
cord-017142-vx3rgs4r	310	20	,	,	,
cord-017142-vx3rgs4r	310	21	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	310	22	,	,	,
cord-017142-vx3rgs4r	310	23	or	or	CC
cord-017142-vx3rgs4r	310	24	amyloid	amyloid	NN
cord-017142-vx3rgs4r	310	25	-	-	HYPH
cord-017142-vx3rgs4r	310	26	related	relate	VBN
cord-017142-vx3rgs4r	310	27	neuropathy	neuropathy	NN
cord-017142-vx3rgs4r	310	28	.	.	.
cord-017142-vx3rgs4r	311	1	Direct	direct	JJ
cord-017142-vx3rgs4r	311	2	involvement	involvement	NN
cord-017142-vx3rgs4r	311	3	by	by	IN
cord-017142-vx3rgs4r	311	4	malignant	malignant	JJ
cord-017142-vx3rgs4r	311	5	cells	cell	NNS
cord-017142-vx3rgs4r	311	6	of	of	IN
cord-017142-vx3rgs4r	311	7	the	the	DT
cord-017142-vx3rgs4r	311	8	central	central	JJ
cord-017142-vx3rgs4r	311	9	nervous	nervous	JJ
cord-017142-vx3rgs4r	311	10	system	system	NN
cord-017142-vx3rgs4r	311	11	(	(	-LRB-
cord-017142-vx3rgs4r	311	12	CNS	CNS	NNP
cord-017142-vx3rgs4r	311	13	)	)	-RRB-
cord-017142-vx3rgs4r	311	14	or	or	CC
cord-017142-vx3rgs4r	311	15	peripheral	peripheral	JJ
cord-017142-vx3rgs4r	311	16	nervous	nervous	JJ
cord-017142-vx3rgs4r	311	17	system	system	NN
cord-017142-vx3rgs4r	311	18	,	,	,
cord-017142-vx3rgs4r	311	19	unlike	unlike	IN
cord-017142-vx3rgs4r	311	20	lymphoma	lymphoma	NN
cord-017142-vx3rgs4r	311	21	,	,	,
cord-017142-vx3rgs4r	311	22	is	be	VBZ
cord-017142-vx3rgs4r	311	23	uncommon	uncommon	JJ
cord-017142-vx3rgs4r	311	24	in	in	IN
cord-017142-vx3rgs4r	311	25	MM	MM	NNP
cord-017142-vx3rgs4r	311	26	.	.	.
cord-017142-vx3rgs4r	312	1	Direct	direct	JJ
cord-017142-vx3rgs4r	312	2	CNS	CNS	NNP
cord-017142-vx3rgs4r	312	3	involvement	involvement	NN
cord-017142-vx3rgs4r	312	4	in	in	IN
cord-017142-vx3rgs4r	312	5	MM	MM	NNP
cord-017142-vx3rgs4r	312	6	often	often	RB
cord-017142-vx3rgs4r	312	7	presents	present	VBZ
cord-017142-vx3rgs4r	312	8	as	as	IN
cord-017142-vx3rgs4r	312	9	leptomeningeal	leptomeningeal	NNP
cord-017142-vx3rgs4r	312	10	myelomatosis	myelomatosis	NNP
cord-017142-vx3rgs4r	312	11	(	(	-LRB-
cord-017142-vx3rgs4r	312	12	LMM	LMM	NNP
cord-017142-vx3rgs4r	312	13	)	)	-RRB-
cord-017142-vx3rgs4r	312	14	,	,	,
cord-017142-vx3rgs4r	312	15	intraparenchymal	intraparenchymal	JJ
cord-017142-vx3rgs4r	312	16	metastasis	metastasis	NN
cord-017142-vx3rgs4r	312	17	,	,	,
cord-017142-vx3rgs4r	312	18	cranial	cranial	JJ
cord-017142-vx3rgs4r	312	19	nerve	nerve	NN
cord-017142-vx3rgs4r	312	20	involvement	involvement	NN
cord-017142-vx3rgs4r	312	21	,	,	,
cord-017142-vx3rgs4r	312	22	or	or	CC
cord-017142-vx3rgs4r	312	23	radiculopathy	radiculopathy	NNP
cord-017142-vx3rgs4r	312	24	[	[	-LRB-
cord-017142-vx3rgs4r	312	25	54	54	CD
cord-017142-vx3rgs4r	312	26	,	,	,
cord-017142-vx3rgs4r	312	27	95	95	CD
cord-017142-vx3rgs4r	312	28	,	,	,
cord-017142-vx3rgs4r	312	29	117	117	CD
cord-017142-vx3rgs4r	312	30	]	]	-RRB-
cord-017142-vx3rgs4r	312	31	.	.	.
cord-017142-vx3rgs4r	313	1	Though	though	IN
cord-017142-vx3rgs4r	313	2	conventional	conventional	JJ
cord-017142-vx3rgs4r	313	3	wisdom	wisdom	NN
cord-017142-vx3rgs4r	313	4	would	would	MD
cord-017142-vx3rgs4r	313	5	suggest	suggest	VB
cord-017142-vx3rgs4r	313	6	CNS	CNS	NNP
cord-017142-vx3rgs4r	313	7	involvement	involvement	NN
cord-017142-vx3rgs4r	313	8	is	be	VBZ
cord-017142-vx3rgs4r	313	9	seen	see	VBN
cord-017142-vx3rgs4r	313	10	later	later	RB
cord-017142-vx3rgs4r	313	11	during	during	IN
cord-017142-vx3rgs4r	313	12	the	the	DT
cord-017142-vx3rgs4r	313	13	disease	disease	NN
cord-017142-vx3rgs4r	313	14	,	,	,
cord-017142-vx3rgs4r	313	15	most	most	JJS
cord-017142-vx3rgs4r	313	16	patients	patient	NNS
cord-017142-vx3rgs4r	313	17	present	present	VBP
cord-017142-vx3rgs4r	313	18	relatively	relatively	RB
cord-017142-vx3rgs4r	313	19	early	early	RB
cord-017142-vx3rgs4r	313	20	with	with	IN
cord-017142-vx3rgs4r	313	21	median	median	JJ
cord-017142-vx3rgs4r	313	22	time	time	NN
cord-017142-vx3rgs4r	313	23	of	of	IN
cord-017142-vx3rgs4r	313	24	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	313	25	of	of	IN
cord-017142-vx3rgs4r	313	26	LMD	LMD	NNP
cord-017142-vx3rgs4r	313	27	around	around	IN
cord-017142-vx3rgs4r	313	28	9	9	CD
cord-017142-vx3rgs4r	313	29	months	month	NNS
cord-017142-vx3rgs4r	313	30	from	from	IN
cord-017142-vx3rgs4r	313	31	MM	MM	NNP
cord-017142-vx3rgs4r	313	32	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	313	33	.	.	.
cord-017142-vx3rgs4r	314	1	Hence	hence	RB
cord-017142-vx3rgs4r	314	2	the	the	DT
cord-017142-vx3rgs4r	314	3	risk	risk	NN
cord-017142-vx3rgs4r	314	4	is	be	VBZ
cord-017142-vx3rgs4r	314	5	unlikely	unlikely	JJ
cord-017142-vx3rgs4r	314	6	only	only	RB
cord-017142-vx3rgs4r	314	7	related	relate	VBN
cord-017142-vx3rgs4r	314	8	to	to	IN
cord-017142-vx3rgs4r	314	9	improved	improve	VBN
cord-017142-vx3rgs4r	314	10	survival	survival	NN
cord-017142-vx3rgs4r	314	11	in	in	IN
cord-017142-vx3rgs4r	314	12	MM	MM	NNP
cord-017142-vx3rgs4r	314	13	patients	patient	NNS
cord-017142-vx3rgs4r	314	14	but	but	CC
cord-017142-vx3rgs4r	314	15	also	also	RB
cord-017142-vx3rgs4r	314	16	due	due	IN
cord-017142-vx3rgs4r	314	17	to	to	IN
cord-017142-vx3rgs4r	314	18	an	an	DT
cord-017142-vx3rgs4r	314	19	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	314	20	early	early	JJ
cord-017142-vx3rgs4r	314	21	biology	biology	NN
cord-017142-vx3rgs4r	314	22	.	.	.
cord-017142-vx3rgs4r	315	1	Supporting	support	VBG
cord-017142-vx3rgs4r	315	2	this	this	DT
cord-017142-vx3rgs4r	315	3	contention	contention	NN
cord-017142-vx3rgs4r	315	4	,	,	,
cord-017142-vx3rgs4r	315	5	CNS	CNS	NNP
cord-017142-vx3rgs4r	315	6	involvement	involvement	NN
cord-017142-vx3rgs4r	315	7	is	be	VBZ
cord-017142-vx3rgs4r	315	8	reported	report	VBN
cord-017142-vx3rgs4r	315	9	mostly	mostly	RB
cord-017142-vx3rgs4r	315	10	in	in	IN
cord-017142-vx3rgs4r	315	11	patients	patient	NNS
cord-017142-vx3rgs4r	315	12	with	with	IN
cord-017142-vx3rgs4r	315	13	high	high	JJ
cord-017142-vx3rgs4r	315	14	-	-	HYPH
cord-017142-vx3rgs4r	315	15	risk	risk	NN
cord-017142-vx3rgs4r	315	16	MM	MM	NNP
cord-017142-vx3rgs4r	315	17	with	with	IN
cord-017142-vx3rgs4r	315	18	heavy	heavy	JJ
cord-017142-vx3rgs4r	315	19	tumor	tumor	NN
cord-017142-vx3rgs4r	315	20	burden	burden	NN
cord-017142-vx3rgs4r	315	21	,	,	,
cord-017142-vx3rgs4r	315	22	plasmablastic	plasmablastic	JJ
cord-017142-vx3rgs4r	315	23	morphology	morphology	NN
cord-017142-vx3rgs4r	315	24	,	,	,
cord-017142-vx3rgs4r	315	25	or	or	CC
cord-017142-vx3rgs4r	315	26	plasma	plasma	NN
cord-017142-vx3rgs4r	315	27	cell	cell	NN
cord-017142-vx3rgs4r	315	28	leukemia	leukemia	NN
cord-017142-vx3rgs4r	315	29	[	[	-LRB-
cord-017142-vx3rgs4r	315	30	138	138	CD
cord-017142-vx3rgs4r	315	31	]	]	-RRB-
cord-017142-vx3rgs4r	315	32	.	.	.
cord-017142-vx3rgs4r	316	1	Patients	patient	NNS
cord-017142-vx3rgs4r	316	2	often	often	RB
cord-017142-vx3rgs4r	316	3	present	present	JJ
cord-017142-vx3rgs4r	316	4	with	with	IN
cord-017142-vx3rgs4r	316	5	focal	focal	JJ
cord-017142-vx3rgs4r	316	6	weakness	weakness	NN
cord-017142-vx3rgs4r	316	7	,	,	,
cord-017142-vx3rgs4r	316	8	cranial	cranial	JJ
cord-017142-vx3rgs4r	316	9	nerve	nerve	NN
cord-017142-vx3rgs4r	316	10	palsies	palsy	NNS
cord-017142-vx3rgs4r	316	11	,	,	,
cord-017142-vx3rgs4r	316	12	mental	mental	JJ
cord-017142-vx3rgs4r	316	13	status	status	NN
cord-017142-vx3rgs4r	316	14	changes	change	NNS
cord-017142-vx3rgs4r	316	15	,	,	,
cord-017142-vx3rgs4r	316	16	speech	speech	NN
cord-017142-vx3rgs4r	316	17	and	and	CC
cord-017142-vx3rgs4r	316	18	gait	gait	JJ
cord-017142-vx3rgs4r	316	19	disturbances	disturbance	NNS
cord-017142-vx3rgs4r	316	20	,	,	,
cord-017142-vx3rgs4r	316	21	symptoms	symptom	NNS
cord-017142-vx3rgs4r	316	22	of	of	IN
cord-017142-vx3rgs4r	316	23	increased	increase	VBN
cord-017142-vx3rgs4r	316	24	intracranial	intracranial	JJ
cord-017142-vx3rgs4r	316	25	pressure	pressure	NN
cord-017142-vx3rgs4r	316	26	,	,	,
cord-017142-vx3rgs4r	316	27	and/or	and/or	CC
cord-017142-vx3rgs4r	316	28	seizures	seizure	NNS
cord-017142-vx3rgs4r	316	29	.	.	.
cord-017142-vx3rgs4r	317	1	CSF	CSF	NNP
cord-017142-vx3rgs4r	317	2	examination	examination	NN
cord-017142-vx3rgs4r	317	3	reveals	reveal	VBZ
cord-017142-vx3rgs4r	317	4	pleocytosis	pleocytosis	NNP
cord-017142-vx3rgs4r	317	5	,	,	,
cord-017142-vx3rgs4r	317	6	increased	increase	VBN
cord-017142-vx3rgs4r	317	7	protein	protein	NN
cord-017142-vx3rgs4r	317	8	levels	level	NNS
cord-017142-vx3rgs4r	317	9	higher	high	JJR
cord-017142-vx3rgs4r	317	10	than	than	IN
cord-017142-vx3rgs4r	317	11	100	100	CD
cord-017142-vx3rgs4r	317	12	g	g	NN
cord-017142-vx3rgs4r	317	13	/	/	SYM
cord-017142-vx3rgs4r	317	14	dL	dl	NN
cord-017142-vx3rgs4r	317	15	,	,	,
cord-017142-vx3rgs4r	317	16	presence	presence	NN
cord-017142-vx3rgs4r	317	17	of	of	IN
cord-017142-vx3rgs4r	317	18	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	317	19	plasma	plasma	NN
cord-017142-vx3rgs4r	317	20	cells	cell	NNS
cord-017142-vx3rgs4r	317	21	,	,	,
cord-017142-vx3rgs4r	317	22	and	and	CC
cord-017142-vx3rgs4r	317	23	in	in	IN
cord-017142-vx3rgs4r	317	24	some	some	DT
cord-017142-vx3rgs4r	317	25	cases	case	NNS
cord-017142-vx3rgs4r	317	26	an	an	DT
cord-017142-vx3rgs4r	317	27	increased	increase	VBN
cord-017142-vx3rgs4r	317	28	opening	opening	NN
cord-017142-vx3rgs4r	317	29	pressure	pressure	NN
cord-017142-vx3rgs4r	317	30	.	.	.
cord-017142-vx3rgs4r	318	1	The	the	DT
cord-017142-vx3rgs4r	318	2	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	318	3	is	be	VBZ
cord-017142-vx3rgs4r	318	4	usually	usually	RB
cord-017142-vx3rgs4r	318	5	reached	reach	VBN
cord-017142-vx3rgs4r	318	6	with	with	IN
cord-017142-vx3rgs4r	318	7	the	the	DT
cord-017142-vx3rgs4r	318	8	first	first	JJ
cord-017142-vx3rgs4r	318	9	analysis	analysis	NN
cord-017142-vx3rgs4r	318	10	of	of	IN
cord-017142-vx3rgs4r	318	11	CSF	CSF	NNP
cord-017142-vx3rgs4r	318	12	[	[	-LRB-
cord-017142-vx3rgs4r	318	13	78	78	CD
cord-017142-vx3rgs4r	318	14	]	]	-RRB-
cord-017142-vx3rgs4r	318	15	.	.	.
cord-017142-vx3rgs4r	319	1	MRI	MRI	NNP
cord-017142-vx3rgs4r	319	2	imaging	image	VBG
cord-017142-vx3rgs4r	319	3	with	with	IN
cord-017142-vx3rgs4r	319	4	and	and	CC
cord-017142-vx3rgs4r	319	5	without	without	IN
cord-017142-vx3rgs4r	319	6	contrast	contrast	NN
cord-017142-vx3rgs4r	319	7	would	would	MD
cord-017142-vx3rgs4r	319	8	aid	aid	VB
cord-017142-vx3rgs4r	319	9	in	in	IN
cord-017142-vx3rgs4r	319	10	identifying	identify	VBG
cord-017142-vx3rgs4r	319	11	the	the	DT
cord-017142-vx3rgs4r	319	12	presence	presence	NN
cord-017142-vx3rgs4r	319	13	and	and	CC
cord-017142-vx3rgs4r	319	14	extent	extent	NN
cord-017142-vx3rgs4r	319	15	of	of	IN
cord-017142-vx3rgs4r	319	16	the	the	DT
cord-017142-vx3rgs4r	319	17	disease	disease	NN
cord-017142-vx3rgs4r	319	18	.	.	.
cord-017142-vx3rgs4r	320	1	In	in	IN
cord-017142-vx3rgs4r	320	2	the	the	DT
cord-017142-vx3rgs4r	320	3	presence	presence	NN
cord-017142-vx3rgs4r	320	4	of	of	IN
cord-017142-vx3rgs4r	320	5	symptoms	symptom	NNS
cord-017142-vx3rgs4r	320	6	,	,	,
cord-017142-vx3rgs4r	320	7	steroids	steroid	NNS
cord-017142-vx3rgs4r	320	8	can	can	MD
cord-017142-vx3rgs4r	320	9	help	help	VB
cord-017142-vx3rgs4r	320	10	in	in	IN
cord-017142-vx3rgs4r	320	11	alleviating	alleviate	VBG
cord-017142-vx3rgs4r	320	12	the	the	DT
cord-017142-vx3rgs4r	320	13	symptoms	symptom	NNS
cord-017142-vx3rgs4r	320	14	and	and	CC
cord-017142-vx3rgs4r	320	15	reducing	reduce	VBG
cord-017142-vx3rgs4r	320	16	intracranial	intracranial	JJ
cord-017142-vx3rgs4r	320	17	pressure	pressure	NN
cord-017142-vx3rgs4r	320	18	.	.	.
cord-017142-vx3rgs4r	321	1	Therapy	therapy	NN
cord-017142-vx3rgs4r	321	2	involves	involve	VBZ
cord-017142-vx3rgs4r	321	3	strategies	strategy	NNS
cord-017142-vx3rgs4r	321	4	similar	similar	JJ
cord-017142-vx3rgs4r	321	5	to	to	IN
cord-017142-vx3rgs4r	321	6	that	that	DT
cord-017142-vx3rgs4r	321	7	used	use	VBN
cord-017142-vx3rgs4r	321	8	for	for	IN
cord-017142-vx3rgs4r	321	9	other	other	JJ
cord-017142-vx3rgs4r	321	10	hematological	hematological	JJ
cord-017142-vx3rgs4r	321	11	malignancies	malignancy	NNS
cord-017142-vx3rgs4r	321	12	with	with	IN
cord-017142-vx3rgs4r	321	13	CNS	CNS	NNP
cord-017142-vx3rgs4r	321	14	involvement	involvement	NN
cord-017142-vx3rgs4r	321	15	,	,	,
cord-017142-vx3rgs4r	321	16	including	include	VBG
cord-017142-vx3rgs4r	321	17	intrathecal	intrathecal	JJ
cord-017142-vx3rgs4r	321	18	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	321	19	and	and	CC
cord-017142-vx3rgs4r	321	20	cranial	cranial	JJ
cord-017142-vx3rgs4r	321	21	irradiation	irradiation	NN
cord-017142-vx3rgs4r	321	22	with	with	IN
cord-017142-vx3rgs4r	321	23	systemic	systemic	JJ
cord-017142-vx3rgs4r	321	24	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	321	25	.	.	.
cord-017142-vx3rgs4r	322	1	Despite	despite	IN
cord-017142-vx3rgs4r	322	2	majority	majority	NN
cord-017142-vx3rgs4r	322	3	of	of	IN
cord-017142-vx3rgs4r	322	4	patients	patient	NNS
cord-017142-vx3rgs4r	322	5	achieving	achieve	VBG
cord-017142-vx3rgs4r	322	6	CSF	CSF	NNP
cord-017142-vx3rgs4r	322	7	clearance	clearance	NN
cord-017142-vx3rgs4r	322	8	with	with	IN
cord-017142-vx3rgs4r	322	9	CNS	CNS	NNP
cord-017142-vx3rgs4r	322	10	-	-	HYPH
cord-017142-vx3rgs4r	322	11	directed	direct	VBN
cord-017142-vx3rgs4r	322	12	therapy	therapy	NN
cord-017142-vx3rgs4r	322	13	showing	show	VBG
cord-017142-vx3rgs4r	322	14	significant	significant	JJ
cord-017142-vx3rgs4r	322	15	potential	potential	NN
cord-017142-vx3rgs4r	322	16	for	for	IN
cord-017142-vx3rgs4r	322	17	symptom	symptom	NN
cord-017142-vx3rgs4r	322	18	improvement	improvement	NN
cord-017142-vx3rgs4r	322	19	,	,	,
cord-017142-vx3rgs4r	322	20	the	the	DT
cord-017142-vx3rgs4r	322	21	overall	overall	JJ
cord-017142-vx3rgs4r	322	22	prognosis	prognosis	NN
cord-017142-vx3rgs4r	322	23	is	be	VBZ
cord-017142-vx3rgs4r	322	24	grim	grim	JJ
cord-017142-vx3rgs4r	322	25	with	with	IN
cord-017142-vx3rgs4r	322	26	the	the	DT
cord-017142-vx3rgs4r	322	27	currently	currently	RB
cord-017142-vx3rgs4r	322	28	approved	approve	VBN
cord-017142-vx3rgs4r	322	29	therapies	therapy	NNS
cord-017142-vx3rgs4r	322	30	in	in	IN
cord-017142-vx3rgs4r	322	31	MM	MM	NNP
cord-017142-vx3rgs4r	322	32	.	.	.
cord-017142-vx3rgs4r	323	1	The	the	DT
cord-017142-vx3rgs4r	323	2	median	median	JJ
cord-017142-vx3rgs4r	323	3	survival	survival	NN
cord-017142-vx3rgs4r	323	4	ranges	range	VBZ
cord-017142-vx3rgs4r	323	5	from	from	IN
cord-017142-vx3rgs4r	323	6	3	3	CD
cord-017142-vx3rgs4r	323	7	to	to	TO
cord-017142-vx3rgs4r	323	8	6	6	CD
cord-017142-vx3rgs4r	323	9	months	month	NNS
cord-017142-vx3rgs4r	323	10	,	,	,
cord-017142-vx3rgs4r	323	11	with	with	IN
cord-017142-vx3rgs4r	323	12	a	a	DT
cord-017142-vx3rgs4r	323	13	small	small	JJ
cord-017142-vx3rgs4r	323	14	fraction	fraction	NN
cord-017142-vx3rgs4r	323	15	surviving	survive	VBG
cord-017142-vx3rgs4r	323	16	past	past	JJ
cord-017142-vx3rgs4r	323	17	2	2	CD
cord-017142-vx3rgs4r	323	18	years	year	NNS
cord-017142-vx3rgs4r	323	19	[	[	-LRB-
cord-017142-vx3rgs4r	323	20	75	75	CD
cord-017142-vx3rgs4r	323	21	]	]	-RRB-
cord-017142-vx3rgs4r	323	22	.	.	.
cord-017142-vx3rgs4r	324	1	Hence	hence	RB
cord-017142-vx3rgs4r	324	2	it	-PRON-	PRP
cord-017142-vx3rgs4r	324	3	is	be	VBZ
cord-017142-vx3rgs4r	324	4	paramount	paramount	NN
cord-017142-vx3rgs4r	324	5	to	to	TO
cord-017142-vx3rgs4r	324	6	have	have	VB
cord-017142-vx3rgs4r	324	7	a	a	DT
cord-017142-vx3rgs4r	324	8	thorough	thorough	JJ
cord-017142-vx3rgs4r	324	9	discussion	discussion	NN
cord-017142-vx3rgs4r	324	10	on	on	IN
cord-017142-vx3rgs4r	324	11	the	the	DT
cord-017142-vx3rgs4r	324	12	goals	goal	NNS
cord-017142-vx3rgs4r	324	13	of	of	IN
cord-017142-vx3rgs4r	324	14	therapy	therapy	NN
cord-017142-vx3rgs4r	324	15	once	once	IN
cord-017142-vx3rgs4r	324	16	CNS	CNS	NNP
cord-017142-vx3rgs4r	324	17	involvement	involvement	NN
cord-017142-vx3rgs4r	324	18	is	be	VBZ
cord-017142-vx3rgs4r	324	19	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	324	20	[	[	-LRB-
cord-017142-vx3rgs4r	324	21	17	17	CD
cord-017142-vx3rgs4r	324	22	,	,	,
cord-017142-vx3rgs4r	324	23	34	34	CD
cord-017142-vx3rgs4r	324	24	]	]	-RRB-
cord-017142-vx3rgs4r	324	25	.	.	.
cord-017142-vx3rgs4r	325	1	Anemia	anemia	NN
cord-017142-vx3rgs4r	325	2	:	:	:
cord-017142-vx3rgs4r	326	1	Hematological	Hematological	NNP
cord-017142-vx3rgs4r	326	2	emergencies	emergency	NNS
cord-017142-vx3rgs4r	326	3	in	in	IN
cord-017142-vx3rgs4r	326	4	MM	MM	NNP
cord-017142-vx3rgs4r	326	5	most	most	RBS
cord-017142-vx3rgs4r	326	6	commonly	commonly	RB
cord-017142-vx3rgs4r	326	7	arise	arise	VBP
cord-017142-vx3rgs4r	326	8	due	due	IN
cord-017142-vx3rgs4r	326	9	to	to	IN
cord-017142-vx3rgs4r	326	10	disease	disease	NN
cord-017142-vx3rgs4r	326	11	-	-	HYPH
cord-017142-vx3rgs4r	326	12	or	or	CC
cord-017142-vx3rgs4r	326	13	treatment	treatment	NN
cord-017142-vx3rgs4r	326	14	-	-	HYPH
cord-017142-vx3rgs4r	326	15	related	relate	VBN
cord-017142-vx3rgs4r	326	16	myelosuppression	myelosuppression	NN
cord-017142-vx3rgs4r	326	17	.	.	.
cord-017142-vx3rgs4r	327	1	Anemia	anemia	NN
cord-017142-vx3rgs4r	327	2	(	(	-LRB-
cord-017142-vx3rgs4r	327	3	Hb	Hb	NNP
cord-017142-vx3rgs4r	327	4	>	>	XX
cord-017142-vx3rgs4r	328	1	2	2	LS
cord-017142-vx3rgs4r	328	2	g	g	NN
cord-017142-vx3rgs4r	328	3	/	/	SYM
cord-017142-vx3rgs4r	328	4	dL	dl	NN
cord-017142-vx3rgs4r	328	5	below	below	IN
cord-017142-vx3rgs4r	328	6	the	the	DT
cord-017142-vx3rgs4r	328	7	lower	low	JJR
cord-017142-vx3rgs4r	328	8	limit	limit	NN
cord-017142-vx3rgs4r	328	9	of	of	IN
cord-017142-vx3rgs4r	328	10	normal	normal	JJ
cord-017142-vx3rgs4r	328	11	or	or	CC
cord-017142-vx3rgs4r	328	12	a	a	DT
cord-017142-vx3rgs4r	328	13	hemoglobin	hemoglobin	NN
cord-017142-vx3rgs4r	328	14	value	value	NN
cord-017142-vx3rgs4r	328	15	<	<	XX
cord-017142-vx3rgs4r	328	16	10	10	CD
cord-017142-vx3rgs4r	328	17	g/	g/	JJ
cord-017142-vx3rgs4r	328	18	dL	dl	NN
cord-017142-vx3rgs4r	328	19	)	)	-RRB-
cord-017142-vx3rgs4r	329	1	is	be	VBZ
cord-017142-vx3rgs4r	329	2	a	a	DT
cord-017142-vx3rgs4r	329	3	common	common	JJ
cord-017142-vx3rgs4r	329	4	complication	complication	NN
cord-017142-vx3rgs4r	329	5	seen	see	VBN
cord-017142-vx3rgs4r	329	6	in	in	IN
cord-017142-vx3rgs4r	329	7	70	70	CD
cord-017142-vx3rgs4r	329	8	-	-	SYM
cord-017142-vx3rgs4r	329	9	80	80	CD
cord-017142-vx3rgs4r	329	10	%	%	NN
cord-017142-vx3rgs4r	329	11	MM	MM	NNP
cord-017142-vx3rgs4r	329	12	patients	patient	NNS
cord-017142-vx3rgs4r	329	13	at	at	IN
cord-017142-vx3rgs4r	329	14	presentation	presentation	NN
cord-017142-vx3rgs4r	329	15	and	and	CC
cord-017142-vx3rgs4r	329	16	in	in	IN
cord-017142-vx3rgs4r	329	17	nearly	nearly	RB
cord-017142-vx3rgs4r	329	18	all	all	DT
cord-017142-vx3rgs4r	329	19	patients	patient	NNS
cord-017142-vx3rgs4r	329	20	at	at	IN
cord-017142-vx3rgs4r	329	21	some	some	DT
cord-017142-vx3rgs4r	329	22	point	point	NN
cord-017142-vx3rgs4r	329	23	in	in	IN
cord-017142-vx3rgs4r	329	24	the	the	DT
cord-017142-vx3rgs4r	329	25	disease	disease	NN
cord-017142-vx3rgs4r	329	26	course	course	NN
cord-017142-vx3rgs4r	329	27	[	[	-LRB-
cord-017142-vx3rgs4r	329	28	64	64	CD
cord-017142-vx3rgs4r	329	29	]	]	-RRB-
cord-017142-vx3rgs4r	329	30	.	.	.
cord-017142-vx3rgs4r	330	1	Several	several	JJ
cord-017142-vx3rgs4r	330	2	factors	factor	NNS
cord-017142-vx3rgs4r	330	3	drive	drive	VBP
cord-017142-vx3rgs4r	330	4	anemia	anemia	NN
cord-017142-vx3rgs4r	330	5	in	in	IN
cord-017142-vx3rgs4r	330	6	MM	MM	NNP
cord-017142-vx3rgs4r	330	7	patients	patient	NNS
cord-017142-vx3rgs4r	330	8	which	which	WDT
cord-017142-vx3rgs4r	330	9	include	include	VBP
cord-017142-vx3rgs4r	330	10	bone	bone	NN
cord-017142-vx3rgs4r	330	11	marrow	marrow	NN
cord-017142-vx3rgs4r	330	12	involvement	involvement	NN
cord-017142-vx3rgs4r	330	13	,	,	,
cord-017142-vx3rgs4r	330	14	low	low	JJ
cord-017142-vx3rgs4r	330	15	serum	serum	NN
cord-017142-vx3rgs4r	330	16	erythropoietin	erythropoietin	NN
cord-017142-vx3rgs4r	330	17	level	level	NN
cord-017142-vx3rgs4r	330	18	due	due	IN
cord-017142-vx3rgs4r	330	19	to	to	IN
cord-017142-vx3rgs4r	330	20	kidney	kidney	NN
cord-017142-vx3rgs4r	330	21	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	330	22	,	,	,
cord-017142-vx3rgs4r	330	23	hemolysis	hemolysis	NN
cord-017142-vx3rgs4r	330	24	,	,	,
cord-017142-vx3rgs4r	330	25	impaired	impaired	JJ
cord-017142-vx3rgs4r	330	26	availability	availability	NN
cord-017142-vx3rgs4r	330	27	of	of	IN
cord-017142-vx3rgs4r	330	28	storage	storage	NN
cord-017142-vx3rgs4r	330	29	iron	iron	NN
cord-017142-vx3rgs4r	330	30	,	,	,
cord-017142-vx3rgs4r	330	31	and	and	CC
cord-017142-vx3rgs4r	330	32	anti	anti	JJ
cord-017142-vx3rgs4r	330	33	-	-	JJ
cord-017142-vx3rgs4r	330	34	MM	mm	JJ
cord-017142-vx3rgs4r	330	35	treatment	treatment	NN
cord-017142-vx3rgs4r	330	36	-	-	HYPH
cord-017142-vx3rgs4r	330	37	related	relate	VBN
cord-017142-vx3rgs4r	330	38	bone	bone	NN
cord-017142-vx3rgs4r	330	39	marrow	marrow	NN
cord-017142-vx3rgs4r	330	40	suppression	suppression	NN
cord-017142-vx3rgs4r	330	41	.	.	.
cord-017142-vx3rgs4r	331	1	An	an	DT
cord-017142-vx3rgs4r	331	2	aggressive	aggressive	JJ
cord-017142-vx3rgs4r	331	3	anti	anti	JJ
cord-017142-vx3rgs4r	331	4	-	-	JJ
cord-017142-vx3rgs4r	331	5	MM	mm	JJ
cord-017142-vx3rgs4r	331	6	treatment	treatment	NN
cord-017142-vx3rgs4r	331	7	approach	approach	NN
cord-017142-vx3rgs4r	331	8	despite	despite	IN
cord-017142-vx3rgs4r	331	9	the	the	DT
cord-017142-vx3rgs4r	331	10	severity	severity	NN
cord-017142-vx3rgs4r	331	11	of	of	IN
cord-017142-vx3rgs4r	331	12	anemia	anemia	NN
cord-017142-vx3rgs4r	331	13	is	be	VBZ
cord-017142-vx3rgs4r	331	14	warranted	warrant	VBN
cord-017142-vx3rgs4r	331	15	in	in	IN
cord-017142-vx3rgs4r	331	16	patients	patient	NNS
cord-017142-vx3rgs4r	331	17	with	with	IN
cord-017142-vx3rgs4r	331	18	anemia	anemia	NN
cord-017142-vx3rgs4r	331	19	suspected	suspect	VBN
cord-017142-vx3rgs4r	331	20	to	to	TO
cord-017142-vx3rgs4r	331	21	be	be	VB
cord-017142-vx3rgs4r	331	22	from	from	IN
cord-017142-vx3rgs4r	331	23	MM	MM	NNP
cord-017142-vx3rgs4r	331	24	.	.	.
cord-017142-vx3rgs4r	332	1	This	this	DT
cord-017142-vx3rgs4r	332	2	is	be	VBZ
cord-017142-vx3rgs4r	332	3	likely	likely	RB
cord-017142-vx3rgs4r	332	4	encountered	encounter	VBN
cord-017142-vx3rgs4r	332	5	in	in	IN
cord-017142-vx3rgs4r	332	6	most	most	JJS
cord-017142-vx3rgs4r	332	7	cases	case	NNS
cord-017142-vx3rgs4r	332	8	of	of	IN
cord-017142-vx3rgs4r	332	9	newly	newly	RB
cord-017142-vx3rgs4r	332	10	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	332	11	MM	MM	NNP
cord-017142-vx3rgs4r	332	12	.	.	.
cord-017142-vx3rgs4r	333	1	Myeloma	myeloma	NN
cord-017142-vx3rgs4r	333	2	therapy	therapy	NN
cord-017142-vx3rgs4r	333	3	often	often	RB
cord-017142-vx3rgs4r	333	4	worsens	worsen	VBZ
cord-017142-vx3rgs4r	333	5	the	the	DT
cord-017142-vx3rgs4r	333	6	anemia	anemia	NN
cord-017142-vx3rgs4r	333	7	,	,	,
cord-017142-vx3rgs4r	333	8	before	before	IN
cord-017142-vx3rgs4r	333	9	it	-PRON-	PRP
cord-017142-vx3rgs4r	333	10	improves	improve	VBZ
cord-017142-vx3rgs4r	333	11	once	once	IN
cord-017142-vx3rgs4r	333	12	myeloma	myeloma	NN
cord-017142-vx3rgs4r	333	13	responds	respond	VBZ
cord-017142-vx3rgs4r	333	14	.	.	.
cord-017142-vx3rgs4r	334	1	These	these	DT
cord-017142-vx3rgs4r	334	2	patients	patient	NNS
cord-017142-vx3rgs4r	334	3	should	should	MD
cord-017142-vx3rgs4r	334	4	be	be	VB
cord-017142-vx3rgs4r	334	5	closely	closely	RB
cord-017142-vx3rgs4r	334	6	monitored	monitor	VBN
cord-017142-vx3rgs4r	334	7	for	for	IN
cord-017142-vx3rgs4r	334	8	transfusion	transfusion	NN
cord-017142-vx3rgs4r	334	9	requirement	requirement	NN
cord-017142-vx3rgs4r	334	10	.	.	.
cord-017142-vx3rgs4r	335	1	No	no	DT
cord-017142-vx3rgs4r	335	2	universal	universal	JJ
cord-017142-vx3rgs4r	335	3	guidelines	guideline	NNS
cord-017142-vx3rgs4r	335	4	exist	exist	VBP
cord-017142-vx3rgs4r	335	5	for	for	IN
cord-017142-vx3rgs4r	335	6	transfusion	transfusion	NN
cord-017142-vx3rgs4r	335	7	goals	goal	NNS
cord-017142-vx3rgs4r	335	8	.	.	.
cord-017142-vx3rgs4r	336	1	In	in	IN
cord-017142-vx3rgs4r	336	2	general	general	JJ
cord-017142-vx3rgs4r	336	3	,	,	,
cord-017142-vx3rgs4r	336	4	leukoreduced	leukoreduced	JJ
cord-017142-vx3rgs4r	336	5	and	and	CC
cord-017142-vx3rgs4r	336	6	irradiated	irradiate	VBN
cord-017142-vx3rgs4r	336	7	blood	blood	NN
cord-017142-vx3rgs4r	336	8	is	be	VBZ
cord-017142-vx3rgs4r	336	9	used	use	VBN
cord-017142-vx3rgs4r	336	10	for	for	IN
cord-017142-vx3rgs4r	336	11	transfusion	transfusion	NN
cord-017142-vx3rgs4r	336	12	for	for	IN
cord-017142-vx3rgs4r	336	13	hemoglobin	hemoglobin	NN
cord-017142-vx3rgs4r	336	14	level	level	NN
cord-017142-vx3rgs4r	336	15	<	<	XX
cord-017142-vx3rgs4r	336	16	7	7	CD
cord-017142-vx3rgs4r	336	17	-	-	SYM
cord-017142-vx3rgs4r	336	18	8	8	CD
cord-017142-vx3rgs4r	336	19	g	g	NN
cord-017142-vx3rgs4r	336	20	/	/	SYM
cord-017142-vx3rgs4r	336	21	dL	dl	NN
cord-017142-vx3rgs4r	336	22	or	or	CC
cord-017142-vx3rgs4r	336	23	symptomatic	symptomatic	JJ
cord-017142-vx3rgs4r	336	24	anemia	anemia	NN
cord-017142-vx3rgs4r	336	25	.	.	.
cord-017142-vx3rgs4r	337	1	The	the	DT
cord-017142-vx3rgs4r	337	2	transfusion	transfusion	NN
cord-017142-vx3rgs4r	337	3	goal	goal	NN
cord-017142-vx3rgs4r	337	4	can	can	MD
cord-017142-vx3rgs4r	337	5	vary	vary	VB
cord-017142-vx3rgs4r	337	6	in	in	IN
cord-017142-vx3rgs4r	337	7	the	the	DT
cord-017142-vx3rgs4r	337	8	presence	presence	NN
cord-017142-vx3rgs4r	337	9	of	of	IN
cord-017142-vx3rgs4r	337	10	other	other	JJ
cord-017142-vx3rgs4r	337	11	comorbidities	comorbiditie	NNS
cord-017142-vx3rgs4r	337	12	such	such	JJ
cord-017142-vx3rgs4r	337	13	as	as	IN
cord-017142-vx3rgs4r	337	14	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	337	15	ischemia	ischemia	NN
cord-017142-vx3rgs4r	337	16	,	,	,
cord-017142-vx3rgs4r	337	17	active	active	JJ
cord-017142-vx3rgs4r	337	18	bleeding	bleeding	NN
cord-017142-vx3rgs4r	337	19	,	,	,
cord-017142-vx3rgs4r	337	20	or	or	CC
cord-017142-vx3rgs4r	337	21	if	if	IN
cord-017142-vx3rgs4r	337	22	symptoms	symptom	NNS
cord-017142-vx3rgs4r	337	23	due	due	JJ
cord-017142-vx3rgs4r	337	24	to	to	IN
cord-017142-vx3rgs4r	337	25	hypoperfusion	hypoperfusion	NN
cord-017142-vx3rgs4r	337	26	are	be	VBP
cord-017142-vx3rgs4r	337	27	present	present	JJ
cord-017142-vx3rgs4r	337	28	.	.	.
cord-017142-vx3rgs4r	338	1	A	a	DT
cord-017142-vx3rgs4r	338	2	major	major	JJ
cord-017142-vx3rgs4r	338	3	proportion	proportion	NN
cord-017142-vx3rgs4r	338	4	of	of	IN
cord-017142-vx3rgs4r	338	5	patients	patient	NNS
cord-017142-vx3rgs4r	338	6	with	with	IN
cord-017142-vx3rgs4r	338	7	MM	MM	NNP
cord-017142-vx3rgs4r	338	8	who	who	WP
cord-017142-vx3rgs4r	338	9	have	have	VBP
cord-017142-vx3rgs4r	338	10	chronic	chronic	JJ
cord-017142-vx3rgs4r	338	11	anemia	anemia	NN
cord-017142-vx3rgs4r	338	12	are	be	VBP
cord-017142-vx3rgs4r	338	13	those	those	DT
cord-017142-vx3rgs4r	338	14	with	with	IN
cord-017142-vx3rgs4r	338	15	long	long	RB
cord-017142-vx3rgs4r	338	16	-	-	HYPH
cord-017142-vx3rgs4r	338	17	standing	stand	VBG
cord-017142-vx3rgs4r	338	18	disease	disease	NN
cord-017142-vx3rgs4r	338	19	in	in	IN
cord-017142-vx3rgs4r	338	20	partial	partial	JJ
cord-017142-vx3rgs4r	338	21	remission	remission	NN
cord-017142-vx3rgs4r	338	22	or	or	CC
cord-017142-vx3rgs4r	338	23	stable	stable	JJ
cord-017142-vx3rgs4r	338	24	response	response	NN
cord-017142-vx3rgs4r	338	25	.	.	.
cord-017142-vx3rgs4r	339	1	Erythropoiesis	erythropoiesis	NN
cord-017142-vx3rgs4r	339	2	-	-	HYPH
cord-017142-vx3rgs4r	339	3	stimulating	stimulate	VBG
cord-017142-vx3rgs4r	339	4	agents	agent	NNS
cord-017142-vx3rgs4r	339	5	are	be	VBP
cord-017142-vx3rgs4r	339	6	not	not	RB
cord-017142-vx3rgs4r	339	7	routinely	routinely	RB
cord-017142-vx3rgs4r	339	8	used	use	VBN
cord-017142-vx3rgs4r	339	9	,	,	,
cord-017142-vx3rgs4r	339	10	except	except	IN
cord-017142-vx3rgs4r	339	11	in	in	IN
cord-017142-vx3rgs4r	339	12	this	this	DT
cord-017142-vx3rgs4r	339	13	population	population	NN
cord-017142-vx3rgs4r	339	14	after	after	IN
cord-017142-vx3rgs4r	339	15	careful	careful	JJ
cord-017142-vx3rgs4r	339	16	selection	selection	NN
cord-017142-vx3rgs4r	339	17	,	,	,
cord-017142-vx3rgs4r	339	18	to	to	TO
cord-017142-vx3rgs4r	339	19	improve	improve	VB
cord-017142-vx3rgs4r	339	20	the	the	DT
cord-017142-vx3rgs4r	339	21	ongoing	ongoing	JJ
cord-017142-vx3rgs4r	339	22	anemia	anemia	NN
cord-017142-vx3rgs4r	339	23	despite	despite	IN
cord-017142-vx3rgs4r	339	24	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	339	25	.	.	.
cord-017142-vx3rgs4r	340	1	Anti	anti	JJ
cord-017142-vx3rgs4r	340	2	-	-	JJ
cord-017142-vx3rgs4r	340	3	MM	mm	JJ
cord-017142-vx3rgs4r	340	4	drug	drug	NN
cord-017142-vx3rgs4r	340	5	-	-	HYPH
cord-017142-vx3rgs4r	340	6	induced	induce	VBN
cord-017142-vx3rgs4r	340	7	TMA	TMA	NNP
cord-017142-vx3rgs4r	340	8	:	:	:
cord-017142-vx3rgs4r	341	1	In	in	IN
cord-017142-vx3rgs4r	341	2	patients	patient	NNS
cord-017142-vx3rgs4r	341	3	who	who	WP
cord-017142-vx3rgs4r	341	4	present	present	VBP
cord-017142-vx3rgs4r	341	5	with	with	IN
cord-017142-vx3rgs4r	341	6	new	new	JJ
cord-017142-vx3rgs4r	341	7	-	-	HYPH
cord-017142-vx3rgs4r	341	8	onset	onset	NN
cord-017142-vx3rgs4r	341	9	anemia	anemia	NN
cord-017142-vx3rgs4r	341	10	and	and	CC
cord-017142-vx3rgs4r	341	11	thrombocytopenia	thrombocytopenia	NN
cord-017142-vx3rgs4r	341	12	,	,	,
cord-017142-vx3rgs4r	341	13	more	more	RBR
cord-017142-vx3rgs4r	341	14	than	than	IN
cord-017142-vx3rgs4r	341	15	often	often	RB
cord-017142-vx3rgs4r	341	16	,	,	,
cord-017142-vx3rgs4r	341	17	it	-PRON-	PRP
cord-017142-vx3rgs4r	341	18	is	be	VBZ
cord-017142-vx3rgs4r	341	19	ascribed	ascribe	VBN
cord-017142-vx3rgs4r	341	20	to	to	IN
cord-017142-vx3rgs4r	341	21	myelosuppressive	myelosuppressive	NNP
cord-017142-vx3rgs4r	341	22	treatment	treatment	NN
cord-017142-vx3rgs4r	341	23	or	or	CC
cord-017142-vx3rgs4r	341	24	for	for	IN
cord-017142-vx3rgs4r	341	25	MM	MM	NNP
cord-017142-vx3rgs4r	341	26	progression	progression	NN
cord-017142-vx3rgs4r	341	27	.	.	.
cord-017142-vx3rgs4r	342	1	In	in	IN
cord-017142-vx3rgs4r	342	2	the	the	DT
cord-017142-vx3rgs4r	342	3	setting	setting	NN
cord-017142-vx3rgs4r	342	4	of	of	IN
cord-017142-vx3rgs4r	342	5	worsening	worsen	VBG
cord-017142-vx3rgs4r	342	6	AKI	AKI	NNP
cord-017142-vx3rgs4r	342	7	,	,	,
cord-017142-vx3rgs4r	342	8	it	-PRON-	PRP
cord-017142-vx3rgs4r	342	9	is	be	VBZ
cord-017142-vx3rgs4r	342	10	imperative	imperative	JJ
cord-017142-vx3rgs4r	342	11	to	to	TO
cord-017142-vx3rgs4r	342	12	check	check	VB
cord-017142-vx3rgs4r	342	13	for	for	IN
cord-017142-vx3rgs4r	342	14	evidence	evidence	NN
cord-017142-vx3rgs4r	342	15	of	of	IN
cord-017142-vx3rgs4r	342	16	hemolysis	hemolysis	NN
cord-017142-vx3rgs4r	342	17	with	with	IN
cord-017142-vx3rgs4r	342	18	a	a	DT
cord-017142-vx3rgs4r	342	19	haptoglobin	haptoglobin	NN
cord-017142-vx3rgs4r	342	20	level	level	NN
cord-017142-vx3rgs4r	342	21	,	,	,
cord-017142-vx3rgs4r	342	22	LDH	LDH	NNP
cord-017142-vx3rgs4r	342	23	level	level	NN
cord-017142-vx3rgs4r	342	24	,	,	,
cord-017142-vx3rgs4r	342	25	and	and	CC
cord-017142-vx3rgs4r	342	26	peripheral	peripheral	JJ
cord-017142-vx3rgs4r	342	27	blood	blood	NN
cord-017142-vx3rgs4r	342	28	smear	smear	NN
cord-017142-vx3rgs4r	342	29	looking	look	VBG
cord-017142-vx3rgs4r	342	30	for	for	IN
cord-017142-vx3rgs4r	342	31	schistocytes	schistocyte	NNS
cord-017142-vx3rgs4r	342	32	.	.	.
cord-017142-vx3rgs4r	343	1	One	one	PRP
cord-017142-vx3rgs4r	343	2	should	should	MD
cord-017142-vx3rgs4r	343	3	strongly	strongly	RB
cord-017142-vx3rgs4r	343	4	consider	consider	VB
cord-017142-vx3rgs4r	343	5	ruling	rule	VBG
cord-017142-vx3rgs4r	343	6	out	out	RP
cord-017142-vx3rgs4r	343	7	TMA	TMA	NNP
cord-017142-vx3rgs4r	343	8	as	as	IN
cord-017142-vx3rgs4r	343	9	it	-PRON-	PRP
cord-017142-vx3rgs4r	343	10	has	have	VBZ
cord-017142-vx3rgs4r	343	11	been	be	VBN
cord-017142-vx3rgs4r	343	12	reported	report	VBN
cord-017142-vx3rgs4r	343	13	with	with	IN
cord-017142-vx3rgs4r	343	14	novel	novel	JJ
cord-017142-vx3rgs4r	343	15	drugs	drug	NNS
cord-017142-vx3rgs4r	343	16	and	and	CC
cord-017142-vx3rgs4r	343	17	with	with	IN
cord-017142-vx3rgs4r	343	18	older	old	JJR
cord-017142-vx3rgs4r	343	19	chemotherapeutic	chemotherapeutic	JJ
cord-017142-vx3rgs4r	343	20	agents	agent	NNS
cord-017142-vx3rgs4r	343	21	;	;	:
cord-017142-vx3rgs4r	343	22	two	two	CD
cord-017142-vx3rgs4r	343	23	notable	notable	JJ
cord-017142-vx3rgs4r	343	24	novel	novel	JJ
cord-017142-vx3rgs4r	343	25	drugs	drug	NNS
cord-017142-vx3rgs4r	343	26	are	be	VBP
cord-017142-vx3rgs4r	343	27	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	343	28	and	and	CC
cord-017142-vx3rgs4r	343	29	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	343	30	,	,	,
cord-017142-vx3rgs4r	343	31	and	and	CC
cord-017142-vx3rgs4r	343	32	a	a	DT
cord-017142-vx3rgs4r	343	33	chemotherapeutic	chemotherapeutic	JJ
cord-017142-vx3rgs4r	343	34	agent	agent	NN
cord-017142-vx3rgs4r	343	35	is	be	VBZ
cord-017142-vx3rgs4r	343	36	cisplatin	cisplatin	JJ
cord-017142-vx3rgs4r	343	37	.	.	.
cord-017142-vx3rgs4r	344	1	Prompt	prompt	JJ
cord-017142-vx3rgs4r	344	2	discontinuation	discontinuation	NN
cord-017142-vx3rgs4r	344	3	of	of	IN
cord-017142-vx3rgs4r	344	4	these	these	DT
cord-017142-vx3rgs4r	344	5	medications	medication	NNS
cord-017142-vx3rgs4r	344	6	is	be	VBZ
cord-017142-vx3rgs4r	344	7	warranted	warrant	VBN
cord-017142-vx3rgs4r	344	8	if	if	IN
cord-017142-vx3rgs4r	344	9	the	the	DT
cord-017142-vx3rgs4r	344	10	medication	medication	NN
cord-017142-vx3rgs4r	344	11	is	be	VBZ
cord-017142-vx3rgs4r	344	12	suspected	suspect	VBN
cord-017142-vx3rgs4r	344	13	to	to	TO
cord-017142-vx3rgs4r	344	14	be	be	VB
cord-017142-vx3rgs4r	344	15	the	the	DT
cord-017142-vx3rgs4r	344	16	likely	likely	JJ
cord-017142-vx3rgs4r	344	17	culprit	culprit	NN
cord-017142-vx3rgs4r	344	18	.	.	.
cord-017142-vx3rgs4r	345	1	Plasmapheresis	Plasmapheresis	NNP
cord-017142-vx3rgs4r	345	2	is	be	VBZ
cord-017142-vx3rgs4r	345	3	initiated	initiate	VBN
cord-017142-vx3rgs4r	345	4	in	in	IN
cord-017142-vx3rgs4r	345	5	most	most	JJS
cord-017142-vx3rgs4r	345	6	of	of	IN
cord-017142-vx3rgs4r	345	7	patients	patient	NNS
cord-017142-vx3rgs4r	345	8	,	,	,
cord-017142-vx3rgs4r	345	9	and	and	CC
cord-017142-vx3rgs4r	345	10	eculizumab	eculizumab	NNP
cord-017142-vx3rgs4r	345	11	has	have	VBZ
cord-017142-vx3rgs4r	345	12	been	be	VBN
cord-017142-vx3rgs4r	345	13	tried	try	VBN
cord-017142-vx3rgs4r	345	14	in	in	IN
cord-017142-vx3rgs4r	345	15	a	a	DT
cord-017142-vx3rgs4r	345	16	small	small	JJ
cord-017142-vx3rgs4r	345	17	number	number	NN
cord-017142-vx3rgs4r	345	18	of	of	IN
cord-017142-vx3rgs4r	345	19	patients	patient	NNS
cord-017142-vx3rgs4r	345	20	.	.	.
cord-017142-vx3rgs4r	346	1	The	the	DT
cord-017142-vx3rgs4r	346	2	role	role	NN
cord-017142-vx3rgs4r	346	3	of	of	IN
cord-017142-vx3rgs4r	346	4	these	these	DT
cord-017142-vx3rgs4r	346	5	two	two	CD
cord-017142-vx3rgs4r	346	6	therapies	therapy	NNS
cord-017142-vx3rgs4r	346	7	in	in	IN
cord-017142-vx3rgs4r	346	8	malignancy	malignancy	NN
cord-017142-vx3rgs4r	346	9	-	-	HYPH
cord-017142-vx3rgs4r	346	10	associated	associate	VBN
cord-017142-vx3rgs4r	346	11	TMA	TMA	NNP
cord-017142-vx3rgs4r	346	12	is	be	VBZ
cord-017142-vx3rgs4r	346	13	controversial	controversial	JJ
cord-017142-vx3rgs4r	346	14	and	and	CC
cord-017142-vx3rgs4r	346	15	should	should	MD
cord-017142-vx3rgs4r	346	16	be	be	VB
cord-017142-vx3rgs4r	346	17	discussed	discuss	VBN
cord-017142-vx3rgs4r	346	18	on	on	IN
cord-017142-vx3rgs4r	346	19	a	a	DT
cord-017142-vx3rgs4r	346	20	case	case	NN
cord-017142-vx3rgs4r	346	21	-	-	HYPH
cord-017142-vx3rgs4r	346	22	by	by	IN
cord-017142-vx3rgs4r	346	23	-	-	HYPH
cord-017142-vx3rgs4r	346	24	case	case	NN
cord-017142-vx3rgs4r	346	25	basis	basis	NN
cord-017142-vx3rgs4r	346	26	[	[	-LRB-
cord-017142-vx3rgs4r	346	27	51	51	CD
cord-017142-vx3rgs4r	346	28	,	,	,
cord-017142-vx3rgs4r	346	29	102	102	CD
cord-017142-vx3rgs4r	346	30	,	,	,
cord-017142-vx3rgs4r	346	31	121	121	CD
cord-017142-vx3rgs4r	346	32	,	,	,
cord-017142-vx3rgs4r	346	33	140	140	CD
cord-017142-vx3rgs4r	346	34	]	]	-RRB-
cord-017142-vx3rgs4r	346	35	.	.	.
cord-017142-vx3rgs4r	347	1	The	the	DT
cord-017142-vx3rgs4r	347	2	novel	novel	JJ
cord-017142-vx3rgs4r	347	3	drug	drug	NN
cord-017142-vx3rgs4r	347	4	combinations	combination	NNS
cord-017142-vx3rgs4r	347	5	with	with	IN
cord-017142-vx3rgs4r	347	6	manageable	manageable	JJ
cord-017142-vx3rgs4r	347	7	adverse	adverse	JJ
cord-017142-vx3rgs4r	347	8	profile	profile	NN
cord-017142-vx3rgs4r	347	9	hold	hold	VBP
cord-017142-vx3rgs4r	347	10	great	great	JJ
cord-017142-vx3rgs4r	347	11	promise	promise	NN
cord-017142-vx3rgs4r	347	12	in	in	IN
cord-017142-vx3rgs4r	347	13	MM	MM	NNP
cord-017142-vx3rgs4r	347	14	,	,	,
cord-017142-vx3rgs4r	347	15	which	which	WDT
cord-017142-vx3rgs4r	347	16	has	have	VBZ
cord-017142-vx3rgs4r	347	17	turned	turn	VBN
cord-017142-vx3rgs4r	347	18	MM	MM	NNP
cord-017142-vx3rgs4r	347	19	into	into	IN
cord-017142-vx3rgs4r	347	20	a	a	DT
cord-017142-vx3rgs4r	347	21	chronic	chronic	JJ
cord-017142-vx3rgs4r	347	22	disease	disease	NN
cord-017142-vx3rgs4r	347	23	with	with	IN
cord-017142-vx3rgs4r	347	24	an	an	DT
cord-017142-vx3rgs4r	347	25	acceptable	acceptable	JJ
cord-017142-vx3rgs4r	347	26	quality	quality	NN
cord-017142-vx3rgs4r	347	27	of	of	IN
cord-017142-vx3rgs4r	347	28	life	life	NN
cord-017142-vx3rgs4r	347	29	for	for	IN
cord-017142-vx3rgs4r	347	30	patients	patient	NNS
cord-017142-vx3rgs4r	347	31	.	.	.
cord-017142-vx3rgs4r	348	1	It	-PRON-	PRP
cord-017142-vx3rgs4r	348	2	is	be	VBZ
cord-017142-vx3rgs4r	348	3	also	also	RB
cord-017142-vx3rgs4r	348	4	crucial	crucial	JJ
cord-017142-vx3rgs4r	348	5	to	to	TO
cord-017142-vx3rgs4r	348	6	recognize	recognize	VB
cord-017142-vx3rgs4r	348	7	the	the	DT
cord-017142-vx3rgs4r	348	8	complications	complication	NNS
cord-017142-vx3rgs4r	348	9	of	of	IN
cord-017142-vx3rgs4r	348	10	MM	MM	NNP
cord-017142-vx3rgs4r	348	11	or	or	CC
cord-017142-vx3rgs4r	348	12	its	-PRON-	PRP$
cord-017142-vx3rgs4r	348	13	treatment	treatment	NN
cord-017142-vx3rgs4r	348	14	and	and	CC
cord-017142-vx3rgs4r	348	15	understand	understand	VB
cord-017142-vx3rgs4r	348	16	the	the	DT
cord-017142-vx3rgs4r	348	17	management	management	NN
cord-017142-vx3rgs4r	348	18	strategies	strategy	NNS
cord-017142-vx3rgs4r	348	19	,	,	,
cord-017142-vx3rgs4r	348	20	which	which	WDT
cord-017142-vx3rgs4r	348	21	could	could	MD
cord-017142-vx3rgs4r	348	22	help	help	VB
cord-017142-vx3rgs4r	348	23	prevent	prevent	VB
cord-017142-vx3rgs4r	348	24	excess	excess	JJ
cord-017142-vx3rgs4r	348	25	morbidity	morbidity	NN
cord-017142-vx3rgs4r	348	26	or	or	CC
cord-017142-vx3rgs4r	348	27	mortality	mortality	NN
cord-017142-vx3rgs4r	348	28	associated	associate	VBN
cord-017142-vx3rgs4r	348	29	with	with	IN
cord-017142-vx3rgs4r	348	30	this	this	DT
cord-017142-vx3rgs4r	348	31	incurable	incurable	JJ
cord-017142-vx3rgs4r	348	32	disease	disease	NN
cord-017142-vx3rgs4r	348	33	.	.	.
cord-017142-vx3rgs4r	349	1	Multiple	multiple	JJ
cord-017142-vx3rgs4r	349	2	myeloma	myeloma	NN
cord-017142-vx3rgs4r	349	3	and	and	CC
cord-017142-vx3rgs4r	349	4	light	light	JJ
cord-017142-vx3rgs4r	349	5	chain	chain	NN
cord-017142-vx3rgs4r	349	6	-	-	HYPH
cord-017142-vx3rgs4r	349	7	associated	associate	VBN
cord-017142-vx3rgs4r	349	8	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	349	9	at	at	IN
cord-017142-vx3rgs4r	349	10	end	end	NN
cord-017142-vx3rgs4r	349	11	-	-	HYPH
cord-017142-vx3rgs4r	349	12	stage	stage	NN
cord-017142-vx3rgs4r	349	13	renal	renal	JJ
cord-017142-vx3rgs4r	349	14	disease	disease	NN
cord-017142-vx3rgs4r	349	15	in	in	IN
cord-017142-vx3rgs4r	349	16	the	the	DT
cord-017142-vx3rgs4r	349	17	United	United	NNP
cord-017142-vx3rgs4r	349	18	States	States	NNP
cord-017142-vx3rgs4r	349	19	:	:	:
cord-017142-vx3rgs4r	349	20	patient	patient	JJ
cord-017142-vx3rgs4r	349	21	characteristics	characteristic	NNS
cord-017142-vx3rgs4r	349	22	and	and	CC
cord-017142-vx3rgs4r	350	1	survival	survival	NN
cord-017142-vx3rgs4r	350	2	Diffuse	diffuse	VBP
cord-017142-vx3rgs4r	350	3	alveolar	alveolar	NN
cord-017142-vx3rgs4r	350	4	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	350	5	in	in	IN
cord-017142-vx3rgs4r	351	1	hematopoietic	hematopoietic	JJ
cord-017142-vx3rgs4r	351	2	stem	stem	NN
cord-017142-vx3rgs4r	351	3	cell	cell	NN
cord-017142-vx3rgs4r	351	4	transplant	transplant	NN
cord-017142-vx3rgs4r	351	5	recipients	recipient	NNS
cord-017142-vx3rgs4r	351	6	Fine	fine	JJ
cord-017142-vx3rgs4r	351	7	-	-	HYPH
cord-017142-vx3rgs4r	351	8	needle	needle	NN
cord-017142-vx3rgs4r	351	9	aspiration	aspiration	NN
cord-017142-vx3rgs4r	351	10	of	of	IN
cord-017142-vx3rgs4r	351	11	abdominal	abdominal	JJ
cord-017142-vx3rgs4r	351	12	fat	fat	JJ
cord-017142-vx3rgs4r	351	13	pad	pad	NN
cord-017142-vx3rgs4r	351	14	for	for	IN
cord-017142-vx3rgs4r	351	15	amyloid	amyloid	NN
cord-017142-vx3rgs4r	351	16	detection	detection	NN
cord-017142-vx3rgs4r	351	17	:	:	:
cord-017142-vx3rgs4r	351	18	a	a	DT
cord-017142-vx3rgs4r	351	19	clinically	clinically	RB
cord-017142-vx3rgs4r	351	20	useful	useful	JJ
cord-017142-vx3rgs4r	351	21	test	test	NN
cord-017142-vx3rgs4r	351	22	?	?	.
cord-017142-vx3rgs4r	352	1	Early	early	JJ
cord-017142-vx3rgs4r	352	2	detection	detection	NN
cord-017142-vx3rgs4r	352	3	and	and	CC
cord-017142-vx3rgs4r	352	4	successful	successful	JJ
cord-017142-vx3rgs4r	352	5	treatment	treatment	NN
cord-017142-vx3rgs4r	352	6	of	of	IN
cord-017142-vx3rgs4r	352	7	drug	drug	NN
cord-017142-vx3rgs4r	352	8	-	-	HYPH
cord-017142-vx3rgs4r	352	9	induced	induce	VBN
cord-017142-vx3rgs4r	352	10	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	352	11	with	with	IN
cord-017142-vx3rgs4r	352	12	corticosteroids	corticosteroid	NNS
cord-017142-vx3rgs4r	352	13	Cardiac	Cardiac	NNP
cord-017142-vx3rgs4r	352	14	complications	complication	NNS
cord-017142-vx3rgs4r	352	15	in	in	IN
cord-017142-vx3rgs4r	352	16	relapsed	relapsed	JJ
cord-017142-vx3rgs4r	352	17	and	and	CC
cord-017142-vx3rgs4r	352	18	refractory	refractory	JJ
cord-017142-vx3rgs4r	352	19	multiple	multiple	JJ
cord-017142-vx3rgs4r	352	20	myeloma	myeloma	NN
cord-017142-vx3rgs4r	352	21	patients	patient	NNS
cord-017142-vx3rgs4r	352	22	treated	treat	VBN
cord-017142-vx3rgs4r	352	23	with	with	IN
cord-017142-vx3rgs4r	352	24	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	352	25	Early	early	JJ
cord-017142-vx3rgs4r	352	26	mortality	mortality	NN
cord-017142-vx3rgs4r	352	27	after	after	IN
cord-017142-vx3rgs4r	352	28	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	352	29	of	of	IN
cord-017142-vx3rgs4r	352	30	multiple	multiple	JJ
cord-017142-vx3rgs4r	352	31	myeloma	myeloma	NN
cord-017142-vx3rgs4r	352	32	:	:	:
cord-017142-vx3rgs4r	352	33	analysis	analysis	NN
cord-017142-vx3rgs4r	352	34	of	of	IN
cord-017142-vx3rgs4r	352	35	patients	patient	NNS
cord-017142-vx3rgs4r	352	36	entered	enter	VBN
cord-017142-vx3rgs4r	352	37	onto	onto	IN
cord-017142-vx3rgs4r	352	38	the	the	DT
cord-017142-vx3rgs4r	352	39	United	United	NNP
cord-017142-vx3rgs4r	352	40	Kingdom	Kingdom	NNP
cord-017142-vx3rgs4r	352	41	Medical	Medical	NNP
cord-017142-vx3rgs4r	352	42	Research	Research	NNP
cord-017142-vx3rgs4r	352	43	Council	Council	NNP
cord-017142-vx3rgs4r	352	44	trials	trial	NNS
cord-017142-vx3rgs4r	352	45	between	between	IN
cord-017142-vx3rgs4r	352	46	1980	1980	CD
cord-017142-vx3rgs4r	352	47	and	and	CC
cord-017142-vx3rgs4r	352	48	2002	2002	CD
cord-017142-vx3rgs4r	353	1	-Medical	-medical	DT
cord-017142-vx3rgs4r	354	1	Research	Research	NNP
cord-017142-vx3rgs4r	354	2	Council	Council	NNP
cord-017142-vx3rgs4r	355	1	Adult	Adult	NNP
cord-017142-vx3rgs4r	355	2	Leukaemia	Leukaemia	NNP
cord-017142-vx3rgs4r	355	3	Working	Working	NNP
cord-017142-vx3rgs4r	355	4	Party	Party	NNP
cord-017142-vx3rgs4r	355	5	Severe	Severe	NNP
cord-017142-vx3rgs4r	355	6	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	355	7	alveolar	alveolar	NN
cord-017142-vx3rgs4r	355	8	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	355	9	associated	associate	VBN
cord-017142-vx3rgs4r	355	10	with	with	IN
cord-017142-vx3rgs4r	355	11	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	355	12	administration	administration	NN
cord-017142-vx3rgs4r	355	13	in	in	IN
cord-017142-vx3rgs4r	355	14	patients	patient	NNS
cord-017142-vx3rgs4r	355	15	with	with	IN
cord-017142-vx3rgs4r	355	16	multiple	multiple	JJ
cord-017142-vx3rgs4r	355	17	myeloma	myeloma	NN
cord-017142-vx3rgs4r	355	18	Bortezomib	Bortezomib	NNP
cord-017142-vx3rgs4r	355	19	-	-	HYPH
cord-017142-vx3rgs4r	355	20	related	relate	VBN
cord-017142-vx3rgs4r	355	21	diffuse	diffuse	NN
cord-017142-vx3rgs4r	356	1	alveolar	alveolar	JJ
cord-017142-vx3rgs4r	356	2	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	356	3	Acute	acute	JJ
cord-017142-vx3rgs4r	356	4	renal	renal	JJ
cord-017142-vx3rgs4r	356	5	failure	failure	NN
cord-017142-vx3rgs4r	356	6	-	-	HYPH
cord-017142-vx3rgs4r	356	7	definition	definition	NN
cord-017142-vx3rgs4r	356	8	,	,	,
cord-017142-vx3rgs4r	356	9	outcome	outcome	NN
cord-017142-vx3rgs4r	356	10	measures	measure	NNS
cord-017142-vx3rgs4r	356	11	,	,	,
cord-017142-vx3rgs4r	356	12	animal	animal	NN
cord-017142-vx3rgs4r	356	13	models	model	NNS
cord-017142-vx3rgs4r	356	14	,	,	,
cord-017142-vx3rgs4r	356	15	fluid	fluid	JJ
cord-017142-vx3rgs4r	356	16	therapy	therapy	NN
cord-017142-vx3rgs4r	356	17	and	and	CC
cord-017142-vx3rgs4r	356	18	information	information	NN
cord-017142-vx3rgs4r	356	19	technology	technology	NN
cord-017142-vx3rgs4r	356	20	needs	need	VBZ
cord-017142-vx3rgs4r	356	21	Cardiac	Cardiac	NNP
cord-017142-vx3rgs4r	356	22	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	356	23	:	:	:
cord-017142-vx3rgs4r	357	1	an	an	DT
cord-017142-vx3rgs4r	357	2	updated	update	VBN
cord-017142-vx3rgs4r	357	3	review	review	NN
cord-017142-vx3rgs4r	357	4	with	with	IN
cord-017142-vx3rgs4r	357	5	emphasis	emphasis	NN
cord-017142-vx3rgs4r	357	6	on	on	IN
cord-017142-vx3rgs4r	357	7	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	357	8	and	and	CC
cord-017142-vx3rgs4r	357	9	future	future	JJ
cord-017142-vx3rgs4r	357	10	directions	direction	NNS
cord-017142-vx3rgs4r	358	1	Renal	renal	JJ
cord-017142-vx3rgs4r	358	2	failure	failure	NN
cord-017142-vx3rgs4r	358	3	in	in	IN
cord-017142-vx3rgs4r	358	4	multiple	multiple	JJ
cord-017142-vx3rgs4r	358	5	myeloma	myeloma	NN
cord-017142-vx3rgs4r	358	6	:	:	:
cord-017142-vx3rgs4r	358	7	presenting	present	VBG
cord-017142-vx3rgs4r	358	8	features	feature	NNS
cord-017142-vx3rgs4r	358	9	and	and	CC
cord-017142-vx3rgs4r	358	10	predictors	predictor	NNS
cord-017142-vx3rgs4r	358	11	of	of	IN
cord-017142-vx3rgs4r	358	12	outcome	outcome	NN
cord-017142-vx3rgs4r	358	13	in	in	IN
cord-017142-vx3rgs4r	358	14	94	94	CD
cord-017142-vx3rgs4r	358	15	patients	patient	NNS
cord-017142-vx3rgs4r	358	16	from	from	IN
cord-017142-vx3rgs4r	358	17	a	a	DT
cord-017142-vx3rgs4r	358	18	single	single	JJ
cord-017142-vx3rgs4r	358	19	institution	institution	NN
cord-017142-vx3rgs4r	358	20	hematologic	hematologic	JJ
cord-017142-vx3rgs4r	358	21	and	and	CC
cord-017142-vx3rgs4r	358	22	infectious	infectious	JJ
cord-017142-vx3rgs4r	358	23	complications	complication	NNS
cord-017142-vx3rgs4r	358	24	in	in	IN
cord-017142-vx3rgs4r	358	25	multiple	multiple	JJ
cord-017142-vx3rgs4r	358	26	myeloma	myeloma	NN
cord-017142-vx3rgs4r	358	27	Malignancies	malignancy	NNS
cord-017142-vx3rgs4r	358	28	,	,	,
cord-017142-vx3rgs4r	358	29	prothrombotic	prothrombotic	JJ
cord-017142-vx3rgs4r	358	30	mutations	mutation	NNS
cord-017142-vx3rgs4r	358	31	,	,	,
cord-017142-vx3rgs4r	358	32	and	and	CC
cord-017142-vx3rgs4r	358	33	the	the	DT
cord-017142-vx3rgs4r	358	34	risk	risk	NN
cord-017142-vx3rgs4r	358	35	of	of	IN
cord-017142-vx3rgs4r	358	36	venous	venous	JJ
cord-017142-vx3rgs4r	358	37	thrombosis	thrombosis	NN
cord-017142-vx3rgs4r	358	38	Treatment	treatment	NN
cord-017142-vx3rgs4r	358	39	of	of	IN
cord-017142-vx3rgs4r	358	40	myeloma	myeloma	NN
cord-017142-vx3rgs4r	358	41	cast	cast	VBN
cord-017142-vx3rgs4r	358	42	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	358	43	(	(	-LRB-
cord-017142-vx3rgs4r	358	44	MCN	MCN	NNP
cord-017142-vx3rgs4r	358	45	)	)	-RRB-
cord-017142-vx3rgs4r	358	46	:	:	:
cord-017142-vx3rgs4r	359	1	a	a	DT
cord-017142-vx3rgs4r	359	2	randomized	randomized	JJ
cord-017142-vx3rgs4r	359	3	trial	trial	NN
cord-017142-vx3rgs4r	359	4	comparing	compare	VBG
cord-017142-vx3rgs4r	359	5	intensive	intensive	JJ
cord-017142-vx3rgs4r	359	6	haemodialysis	haemodialysis	NNP
cord-017142-vx3rgs4r	359	7	(	(	-LRB-
cord-017142-vx3rgs4r	359	8	HD	HD	NNP
cord-017142-vx3rgs4r	359	9	)	)	-RRB-
cord-017142-vx3rgs4r	359	10	with	with	IN
cord-017142-vx3rgs4r	359	11	high	high	JJ
cord-017142-vx3rgs4r	359	12	cut	cut	VBN
cord-017142-vx3rgs4r	359	13	-	-	HYPH
cord-017142-vx3rgs4r	359	14	off	off	NN
cord-017142-vx3rgs4r	359	15	(	(	-LRB-
cord-017142-vx3rgs4r	359	16	HCO	HCO	NNP
cord-017142-vx3rgs4r	359	17	)	)	-RRB-
cord-017142-vx3rgs4r	359	18	or	or	CC
cord-017142-vx3rgs4r	359	19	standard	standard	JJ
cord-017142-vx3rgs4r	359	20	high	high	JJ
cord-017142-vx3rgs4r	359	21	-	-	HYPH
cord-017142-vx3rgs4r	359	22	flux	flux	NN
cord-017142-vx3rgs4r	359	23	dialyzer	dialyzer	NN
cord-017142-vx3rgs4r	359	24	in	in	IN
cord-017142-vx3rgs4r	359	25	patients	patient	NNS
cord-017142-vx3rgs4r	359	26	receiving	receive	VBG
cord-017142-vx3rgs4r	359	27	a	a	DT
cord-017142-vx3rgs4r	359	28	bortezomib	bortezomib	NN
cord-017142-vx3rgs4r	359	29	-	-	HYPH
cord-017142-vx3rgs4r	359	30	based	base	VBN
cord-017142-vx3rgs4r	359	31	regimen	regimen	NN
cord-017142-vx3rgs4r	359	32	(	(	-LRB-
cord-017142-vx3rgs4r	359	33	the	the	DT
cord-017142-vx3rgs4r	359	34	MYRE	MYRE	NNP
cord-017142-vx3rgs4r	359	35	Study	Study	NNP
cord-017142-vx3rgs4r	359	36	,	,	,
cord-017142-vx3rgs4r	359	37	by	by	IN
cord-017142-vx3rgs4r	359	38	the	the	DT
cord-017142-vx3rgs4r	359	39	Intergroupe	Intergroupe	NNP
cord-017142-vx3rgs4r	359	40	Francophone	Francophone	NNP
cord-017142-vx3rgs4r	359	41	du	du	NNP
cord-017142-vx3rgs4r	359	42	Myélome	Myélome	NNP
cord-017142-vx3rgs4r	359	43	(	(	-LRB-
cord-017142-vx3rgs4r	359	44	IFM	IFM	NNP
cord-017142-vx3rgs4r	359	45	)	)	-RRB-
cord-017142-vx3rgs4r	359	46	and	and	CC
cord-017142-vx3rgs4r	359	47	the	the	DT
cord-017142-vx3rgs4r	359	48	French	French	NNP
cord-017142-vx3rgs4r	359	49	Society	Society	NNP
cord-017142-vx3rgs4r	359	50	of	of	IN
cord-017142-vx3rgs4r	359	51	Fanconi	Fanconi	NNP
cord-017142-vx3rgs4r	359	52	's	's	POS
cord-017142-vx3rgs4r	359	53	syndrome	syndrome	NN
cord-017142-vx3rgs4r	359	54	induced	induce	VBN
cord-017142-vx3rgs4r	359	55	by	by	IN
cord-017142-vx3rgs4r	359	56	a	a	DT
cord-017142-vx3rgs4r	359	57	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	359	58	Vκ3	vκ3	NN
cord-017142-vx3rgs4r	359	59	light	light	JJ
cord-017142-vx3rgs4r	359	60	chain	chain	NN
cord-017142-vx3rgs4r	359	61	in	in	IN
cord-017142-vx3rgs4r	359	62	Waldenström	Waldenström	NNP
cord-017142-vx3rgs4r	359	63	's	's	POS
cord-017142-vx3rgs4r	359	64	macroglobulinemia	macroglobulinemia	NN
cord-017142-vx3rgs4r	359	65	Thalidomide	Thalidomide	NNP
cord-017142-vx3rgs4r	359	66	-	-	HYPH
cord-017142-vx3rgs4r	359	67	induced	induce	VBN
cord-017142-vx3rgs4r	359	68	reversible	reversible	JJ
cord-017142-vx3rgs4r	359	69	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	359	70	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	359	71	in	in	IN
cord-017142-vx3rgs4r	359	72	a	a	DT
cord-017142-vx3rgs4r	359	73	patient	patient	NN
cord-017142-vx3rgs4r	359	74	with	with	IN
cord-017142-vx3rgs4r	359	75	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	359	76	ovarian	ovarian	JJ
cord-017142-vx3rgs4r	359	77	cancer	cancer	NN
cord-017142-vx3rgs4r	359	78	Intracranial	intracranial	JJ
cord-017142-vx3rgs4r	359	79	involvement	involvement	NN
cord-017142-vx3rgs4r	359	80	in	in	IN
cord-017142-vx3rgs4r	359	81	plasmacytomas	plasmacytomas	NN
cord-017142-vx3rgs4r	359	82	and	and	CC
cord-017142-vx3rgs4r	359	83	multiple	multiple	JJ
cord-017142-vx3rgs4r	359	84	myeloma	myeloma	NN
cord-017142-vx3rgs4r	359	85	:	:	:
cord-017142-vx3rgs4r	359	86	a	a	DT
cord-017142-vx3rgs4r	359	87	pictorial	pictorial	JJ
cord-017142-vx3rgs4r	359	88	essay	essay	NN
cord-017142-vx3rgs4r	359	89	Tumor	tumor	NN
cord-017142-vx3rgs4r	359	90	lysis	lysis	NN
cord-017142-vx3rgs4r	359	91	syndrome	syndrome	NN
cord-017142-vx3rgs4r	359	92	in	in	IN
cord-017142-vx3rgs4r	359	93	patients	patient	NNS
cord-017142-vx3rgs4r	359	94	with	with	IN
cord-017142-vx3rgs4r	359	95	light	light	JJ
cord-017142-vx3rgs4r	359	96	chain	chain	NN
cord-017142-vx3rgs4r	359	97	multiple	multiple	JJ
cord-017142-vx3rgs4r	359	98	myeloma	myeloma	NN
cord-017142-vx3rgs4r	359	99	:	:	:
cord-017142-vx3rgs4r	359	100	report	report	NN
cord-017142-vx3rgs4r	359	101	of	of	IN
cord-017142-vx3rgs4r	359	102	two	two	CD
cord-017142-vx3rgs4r	359	103	cases	case	NNS
cord-017142-vx3rgs4r	359	104	Renal	renal	JJ
cord-017142-vx3rgs4r	359	105	failure	failure	NN
cord-017142-vx3rgs4r	359	106	with	with	IN
cord-017142-vx3rgs4r	359	107	the	the	DT
cord-017142-vx3rgs4r	359	108	use	use	NN
cord-017142-vx3rgs4r	359	109	of	of	IN
cord-017142-vx3rgs4r	359	110	zoledronic	zoledronic	NNP
cord-017142-vx3rgs4r	359	111	acid	acid	JJ
cord-017142-vx3rgs4r	359	112	Lenalidomide	Lenalidomide	NNP
cord-017142-vx3rgs4r	359	113	-	-	HYPH
cord-017142-vx3rgs4r	359	114	induced	induce	VBN
cord-017142-vx3rgs4r	359	115	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	359	116	lung	lung	NN
cord-017142-vx3rgs4r	359	117	disease	disease	NN
cord-017142-vx3rgs4r	359	118	Plasma	Plasma	NNP
cord-017142-vx3rgs4r	359	119	exchange	exchange	NN
cord-017142-vx3rgs4r	359	120	when	when	WRB
cord-017142-vx3rgs4r	359	121	myeloma	myeloma	NN
cord-017142-vx3rgs4r	359	122	presents	present	VBZ
cord-017142-vx3rgs4r	359	123	as	as	IN
cord-017142-vx3rgs4r	359	124	acute	acute	JJ
cord-017142-vx3rgs4r	359	125	renal	renal	JJ
cord-017142-vx3rgs4r	359	126	failure	failure	NN
cord-017142-vx3rgs4r	359	127	:	:	:
cord-017142-vx3rgs4r	359	128	a	a	DT
cord-017142-vx3rgs4r	359	129	randomized	randomized	JJ
cord-017142-vx3rgs4r	359	130	,	,	,
cord-017142-vx3rgs4r	359	131	controlled	control	VBN
cord-017142-vx3rgs4r	359	132	trial	trial	NN
cord-017142-vx3rgs4r	359	133	High	high	JJ
cord-017142-vx3rgs4r	359	134	cut	cut	VB
cord-017142-vx3rgs4r	359	135	-	-	HYPH
cord-017142-vx3rgs4r	359	136	off	off	RP
cord-017142-vx3rgs4r	359	137	haemodialysis	haemodialysis	NNP
cord-017142-vx3rgs4r	359	138	(	(	-LRB-
cord-017142-vx3rgs4r	359	139	HCO	HCO	NNP
cord-017142-vx3rgs4r	359	140	-	-	HYPH
cord-017142-vx3rgs4r	359	141	HD	HD	NNP
cord-017142-vx3rgs4r	359	142	)	)	-RRB-
cord-017142-vx3rgs4r	359	143	does	do	VBZ
cord-017142-vx3rgs4r	359	144	not	not	RB
cord-017142-vx3rgs4r	359	145	improve	improve	VB
cord-017142-vx3rgs4r	359	146	outcomes	outcome	NNS
cord-017142-vx3rgs4r	359	147	in	in	IN
cord-017142-vx3rgs4r	359	148	myeloma	myeloma	NN
cord-017142-vx3rgs4r	359	149	cast	cast	VBN
cord-017142-vx3rgs4r	359	150	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	359	151	:	:	:
cord-017142-vx3rgs4r	359	152	results	result	NNS
cord-017142-vx3rgs4r	359	153	of	of	IN
cord-017142-vx3rgs4r	359	154	European	european	JJ
cord-017142-vx3rgs4r	359	155	trial	trial	NN
cord-017142-vx3rgs4r	359	156	of	of	IN
cord-017142-vx3rgs4r	359	157	Free	Free	NNP
cord-017142-vx3rgs4r	359	158	Light	Light	NNP
cord-017142-vx3rgs4r	359	159	Chain	Chain	NNP
cord-017142-vx3rgs4r	359	160	removal	removal	NN
cord-017142-vx3rgs4r	359	161	by	by	IN
cord-017142-vx3rgs4r	359	162	extended	extended	JJ
cord-017142-vx3rgs4r	359	163	haemodialysis	haemodialysis	NN
cord-017142-vx3rgs4r	359	164	in	in	IN
cord-017142-vx3rgs4r	359	165	cast	cast	NN
cord-017142-vx3rgs4r	359	166	nephropathy	nephropathy	NN
cord-017142-vx3rgs4r	359	167	Rapid	Rapid	NNP
cord-017142-vx3rgs4r	359	168	complete	complete	JJ
cord-017142-vx3rgs4r	359	169	remission	remission	NN
cord-017142-vx3rgs4r	359	170	in	in	IN
cord-017142-vx3rgs4r	359	171	multiple	multiple	JJ
cord-017142-vx3rgs4r	359	172	myeloma	myeloma	NN
cord-017142-vx3rgs4r	359	173	with	with	IN
cord-017142-vx3rgs4r	359	174	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	359	175	/	/	SYM
cord-017142-vx3rgs4r	359	176	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	359	177	/	/	SYM
cord-017142-vx3rgs4r	359	178	dexamethasone	dexamethasone	NN
cord-017142-vx3rgs4r	359	179	combination	combination	NN
cord-017142-vx3rgs4r	359	180	therapy	therapy	NN
cord-017142-vx3rgs4r	359	181	following	follow	VBG
cord-017142-vx3rgs4r	359	182	development	development	NN
cord-017142-vx3rgs4r	359	183	of	of	IN
cord-017142-vx3rgs4r	359	184	tumor	tumor	NN
cord-017142-vx3rgs4r	359	185	lysis	lysis	NN
cord-017142-vx3rgs4r	359	186	syndrome	syndrome	NN
cord-017142-vx3rgs4r	359	187	Effect	effect	NN
cord-017142-vx3rgs4r	359	188	of	of	IN
cord-017142-vx3rgs4r	359	189	steroid	steroid	NN
cord-017142-vx3rgs4r	359	190	therapy	therapy	NN
cord-017142-vx3rgs4r	359	191	on	on	IN
cord-017142-vx3rgs4r	359	192	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	359	193	and	and	CC
cord-017142-vx3rgs4r	359	194	renal	renal	JJ
cord-017142-vx3rgs4r	359	195	insufficiency	insufficiency	NN
cord-017142-vx3rgs4r	359	196	in	in	IN
cord-017142-vx3rgs4r	359	197	sarcoidosis	sarcoidosis	NN
cord-017142-vx3rgs4r	359	198	Alveolar	alveolar	NN
cord-017142-vx3rgs4r	359	199	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	359	200	.	.	.
cord-017142-vx3rgs4r	360	1	Diagnostic	diagnostic	JJ
cord-017142-vx3rgs4r	360	2	criteria	criterion	NNS
cord-017142-vx3rgs4r	360	3	and	and	CC
cord-017142-vx3rgs4r	360	4	results	result	NNS
cord-017142-vx3rgs4r	360	5	in	in	IN
cord-017142-vx3rgs4r	360	6	194	194	CD
cord-017142-vx3rgs4r	360	7	immunocompromised	immunocompromised	JJ
cord-017142-vx3rgs4r	360	8	hosts	host	NNS
cord-017142-vx3rgs4r	360	9	New	new	JJ
cord-017142-vx3rgs4r	360	10	anticoagulants	anticoagulant	NNS
cord-017142-vx3rgs4r	360	11	in	in	IN
cord-017142-vx3rgs4r	360	12	the	the	DT
cord-017142-vx3rgs4r	360	13	treatment	treatment	NN
cord-017142-vx3rgs4r	360	14	of	of	IN
cord-017142-vx3rgs4r	360	15	patients	patient	NNS
cord-017142-vx3rgs4r	360	16	with	with	IN
cord-017142-vx3rgs4r	360	17	cancer	cancer	NN
cord-017142-vx3rgs4r	360	18	-	-	HYPH
cord-017142-vx3rgs4r	360	19	associated	associate	VBN
cord-017142-vx3rgs4r	360	20	venous	venous	JJ
cord-017142-vx3rgs4r	360	21	thromboembolism	thromboembolism	NN
cord-017142-vx3rgs4r	360	22	Metabolic	metabolic	JJ
cord-017142-vx3rgs4r	360	23	disorders	disorder	NNS
cord-017142-vx3rgs4r	360	24	in	in	IN
cord-017142-vx3rgs4r	360	25	hematologic	hematologic	JJ
cord-017142-vx3rgs4r	360	26	malignancies	malignancy	NNS
cord-017142-vx3rgs4r	360	27	-	-	:
cord-017142-vx3rgs4r	360	28	A	a	DT
cord-017142-vx3rgs4r	360	29	review	review	NN
cord-017142-vx3rgs4r	361	1	Guidelines	guideline	NNS
cord-017142-vx3rgs4r	361	2	for	for	IN
cord-017142-vx3rgs4r	361	3	standard	standard	JJ
cord-017142-vx3rgs4r	361	4	investigative	investigative	JJ
cord-017142-vx3rgs4r	361	5	workup	workup	NN
cord-017142-vx3rgs4r	361	6	:	:	:
cord-017142-vx3rgs4r	361	7	report	report	NN
cord-017142-vx3rgs4r	361	8	of	of	IN
cord-017142-vx3rgs4r	361	9	the	the	DT
cord-017142-vx3rgs4r	361	10	International	International	NNP
cord-017142-vx3rgs4r	361	11	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	361	12	Workshop	Workshop	NNP
cord-017142-vx3rgs4r	361	13	Consensus	Consensus	NNP
cord-017142-vx3rgs4r	361	14	Panel	Panel	NNP
cord-017142-vx3rgs4r	361	15	3	3	CD
cord-017142-vx3rgs4r	361	16	Renal	renal	JJ
cord-017142-vx3rgs4r	361	17	impairment	impairment	NN
cord-017142-vx3rgs4r	361	18	in	in	IN
cord-017142-vx3rgs4r	361	19	patients	patient	NNS
cord-017142-vx3rgs4r	361	20	with	with	IN
cord-017142-vx3rgs4r	361	21	multiple	multiple	JJ
cord-017142-vx3rgs4r	361	22	myeloma	myeloma	NN
cord-017142-vx3rgs4r	361	23	:	:	:
cord-017142-vx3rgs4r	362	1	a	a	DT
cord-017142-vx3rgs4r	362	2	consensus	consensus	NN
cord-017142-vx3rgs4r	362	3	statement	statement	NN
cord-017142-vx3rgs4r	362	4	on	on	IN
cord-017142-vx3rgs4r	362	5	behalf	behalf	NN
cord-017142-vx3rgs4r	362	6	of	of	IN
cord-017142-vx3rgs4r	362	7	the	the	DT
cord-017142-vx3rgs4r	362	8	International	International	NNP
cord-017142-vx3rgs4r	362	9	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	362	10	Working	Working	NNP
cord-017142-vx3rgs4r	362	11	Group	Group	NNP
cord-017142-vx3rgs4r	362	12	VMP	VMP	NNP
cord-017142-vx3rgs4r	362	13	(	(	-LRB-
cord-017142-vx3rgs4r	362	14	Bortezomib	Bortezomib	NNP
cord-017142-vx3rgs4r	362	15	,	,	,
cord-017142-vx3rgs4r	362	16	Melphalan	Melphalan	NNP
cord-017142-vx3rgs4r	362	17	,	,	,
cord-017142-vx3rgs4r	362	18	and	and	CC
cord-017142-vx3rgs4r	362	19	Prednisone	Prednisone	NNP
cord-017142-vx3rgs4r	362	20	)	)	-RRB-
cord-017142-vx3rgs4r	362	21	is	be	VBZ
cord-017142-vx3rgs4r	362	22	active	active	JJ
cord-017142-vx3rgs4r	362	23	and	and	CC
cord-017142-vx3rgs4r	362	24	well	well	RB
cord-017142-vx3rgs4r	362	25	tolerated	tolerate	VBN
cord-017142-vx3rgs4r	362	26	in	in	IN
cord-017142-vx3rgs4r	362	27	newly	newly	RB
cord-017142-vx3rgs4r	362	28	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	362	29	patients	patient	NNS
cord-017142-vx3rgs4r	362	30	with	with	IN
cord-017142-vx3rgs4r	362	31	multiple	multiple	JJ
cord-017142-vx3rgs4r	362	32	myeloma	myeloma	NN
cord-017142-vx3rgs4r	362	33	with	with	IN
cord-017142-vx3rgs4r	362	34	moderately	moderately	RB
cord-017142-vx3rgs4r	362	35	impaired	impaired	JJ
cord-017142-vx3rgs4r	362	36	renal	renal	JJ
cord-017142-vx3rgs4r	362	37	function	function	NN
cord-017142-vx3rgs4r	362	38	,	,	,
cord-017142-vx3rgs4r	362	39	and	and	CC
cord-017142-vx3rgs4r	362	40	results	result	NNS
cord-017142-vx3rgs4r	362	41	in	in	IN
cord-017142-vx3rgs4r	362	42	reversal	reversal	NN
cord-017142-vx3rgs4r	362	43	of	of	IN
cord-017142-vx3rgs4r	362	44	renal	renal	JJ
cord-017142-vx3rgs4r	362	45	impairment	impairment	NN
cord-017142-vx3rgs4r	362	46	:	:	:
cord-017142-vx3rgs4r	362	47	cohort	cohort	NN
cord-017142-vx3rgs4r	362	48	analysis	analysis	NN
cord-017142-vx3rgs4r	362	49	of	of	IN
cord-017142-vx3rgs4r	362	50	the	the	DT
cord-017142-vx3rgs4r	362	51	phase	phase	NN
cord-017142-vx3rgs4r	362	52	III	iii	CD
cord-017142-vx3rgs4r	362	53	VISTA	VISTA	NNP
cord-017142-vx3rgs4r	362	54	study	study	NN
cord-017142-vx3rgs4r	362	55	Neurologic	neurologic	JJ
cord-017142-vx3rgs4r	362	56	complications	complication	NNS
cord-017142-vx3rgs4r	362	57	of	of	IN
cord-017142-vx3rgs4r	362	58	plasma	plasma	NN
cord-017142-vx3rgs4r	362	59	cell	cell	NN
cord-017142-vx3rgs4r	362	60	disorders	disorder	NNS
cord-017142-vx3rgs4r	363	1	The	the	DT
cord-017142-vx3rgs4r	363	2	clinical	clinical	JJ
cord-017142-vx3rgs4r	363	3	features	feature	NNS
cord-017142-vx3rgs4r	363	4	of	of	IN
cord-017142-vx3rgs4r	363	5	immunoglobulin	immunoglobulin	NN
cord-017142-vx3rgs4r	363	6	light	light	JJ
cord-017142-vx3rgs4r	363	7	-	-	HYPH
cord-017142-vx3rgs4r	363	8	chain	chain	NN
cord-017142-vx3rgs4r	363	9	(	(	-LRB-
cord-017142-vx3rgs4r	363	10	AL	AL	NNP
cord-017142-vx3rgs4r	363	11	)	)	-RRB-
cord-017142-vx3rgs4r	363	12	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	363	13	with	with	IN
cord-017142-vx3rgs4r	363	14	heart	heart	NN
cord-017142-vx3rgs4r	363	15	involvement	involvement	NN
cord-017142-vx3rgs4r	363	16	Acquired	acquire	VBD
cord-017142-vx3rgs4r	363	17	resistance	resistance	NN
cord-017142-vx3rgs4r	363	18	to	to	IN
cord-017142-vx3rgs4r	363	19	activated	activate	VBN
cord-017142-vx3rgs4r	363	20	protein	protein	NN
cord-017142-vx3rgs4r	363	21	C	C	NNP
cord-017142-vx3rgs4r	363	22	(	(	-LRB-
cord-017142-vx3rgs4r	363	23	aAPCR	aAPCR	NNP
cord-017142-vx3rgs4r	363	24	)	)	-RRB-
cord-017142-vx3rgs4r	363	25	in	in	IN
cord-017142-vx3rgs4r	363	26	multiple	multiple	JJ
cord-017142-vx3rgs4r	363	27	myeloma	myeloma	NN
cord-017142-vx3rgs4r	363	28	is	be	VBZ
cord-017142-vx3rgs4r	363	29	a	a	DT
cord-017142-vx3rgs4r	363	30	transitory	transitory	JJ
cord-017142-vx3rgs4r	363	31	abnormality	abnormality	NN
cord-017142-vx3rgs4r	363	32	associated	associate	VBN
cord-017142-vx3rgs4r	363	33	with	with	IN
cord-017142-vx3rgs4r	363	34	an	an	DT
cord-017142-vx3rgs4r	363	35	increased	increase	VBN
cord-017142-vx3rgs4r	363	36	risk	risk	NN
cord-017142-vx3rgs4r	363	37	of	of	IN
cord-017142-vx3rgs4r	363	38	venous	venous	JJ
cord-017142-vx3rgs4r	363	39	thromboembolism	thromboembolism	NN
cord-017142-vx3rgs4r	363	40	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	363	41	of	of	IN
cord-017142-vx3rgs4r	363	42	the	the	DT
cord-017142-vx3rgs4r	363	43	central	central	JJ
cord-017142-vx3rgs4r	363	44	nervous	nervous	JJ
cord-017142-vx3rgs4r	363	45	system	system	NN
cord-017142-vx3rgs4r	363	46	:	:	:
cord-017142-vx3rgs4r	363	47	strong	strong	JJ
cord-017142-vx3rgs4r	363	48	association	association	NN
cord-017142-vx3rgs4r	363	49	with	with	IN
cord-017142-vx3rgs4r	363	50	unfavorable	unfavorable	JJ
cord-017142-vx3rgs4r	363	51	chromosomal	chromosomal	JJ
cord-017142-vx3rgs4r	363	52	abnormalities	abnormality	NNS
cord-017142-vx3rgs4r	363	53	and	and	CC
cord-017142-vx3rgs4r	363	54	other	other	JJ
cord-017142-vx3rgs4r	363	55	high	high	JJ
cord-017142-vx3rgs4r	363	56	-	-	HYPH
cord-017142-vx3rgs4r	363	57	risk	risk	NN
cord-017142-vx3rgs4r	363	58	disease	disease	NN
cord-017142-vx3rgs4r	363	59	features	feature	VBZ
cord-017142-vx3rgs4r	363	60	Tumour	tumour	NN
cord-017142-vx3rgs4r	363	61	lysis	lysis	NN
cord-017142-vx3rgs4r	363	62	syndrome	syndrome	NN
cord-017142-vx3rgs4r	363	63	complicating	complicate	VBG
cord-017142-vx3rgs4r	363	64	high	high	JJ
cord-017142-vx3rgs4r	363	65	-	-	HYPH
cord-017142-vx3rgs4r	363	66	dose	dose	NN
cord-017142-vx3rgs4r	363	67	treatment	treatment	NN
cord-017142-vx3rgs4r	363	68	in	in	IN
cord-017142-vx3rgs4r	363	69	patients	patient	NNS
cord-017142-vx3rgs4r	363	70	with	with	IN
cord-017142-vx3rgs4r	363	71	multiple	multiple	JJ
cord-017142-vx3rgs4r	363	72	myeloma	myeloma	NN
cord-017142-vx3rgs4r	363	73	Intracardiac	Intracardiac	NNP
cord-017142-vx3rgs4r	363	74	thrombosis	thrombosis	NN
cord-017142-vx3rgs4r	363	75	and	and	CC
cord-017142-vx3rgs4r	363	76	anticoagulation	anticoagulation	NN
cord-017142-vx3rgs4r	363	77	therapy	therapy	NN
cord-017142-vx3rgs4r	363	78	in	in	IN
cord-017142-vx3rgs4r	363	79	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	363	80	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	363	81	Denosumab	Denosumab	NNP
cord-017142-vx3rgs4r	363	82	versus	versus	IN
cord-017142-vx3rgs4r	363	83	zoledronic	zoledronic	NNP
cord-017142-vx3rgs4r	363	84	acid	acid	NN
cord-017142-vx3rgs4r	363	85	for	for	IN
cord-017142-vx3rgs4r	363	86	treatment	treatment	NN
cord-017142-vx3rgs4r	363	87	of	of	IN
cord-017142-vx3rgs4r	363	88	bone	bone	NN
cord-017142-vx3rgs4r	363	89	metastases	metastasis	NNS
cord-017142-vx3rgs4r	363	90	in	in	IN
cord-017142-vx3rgs4r	363	91	men	man	NNS
cord-017142-vx3rgs4r	363	92	with	with	IN
cord-017142-vx3rgs4r	363	93	castration	castration	NN
cord-017142-vx3rgs4r	363	94	-	-	HYPH
cord-017142-vx3rgs4r	363	95	resistant	resistant	JJ
cord-017142-vx3rgs4r	363	96	prostate	prostate	NN
cord-017142-vx3rgs4r	363	97	cancer	cancer	NN
cord-017142-vx3rgs4r	363	98	:	:	:
cord-017142-vx3rgs4r	364	1	a	a	DT
cord-017142-vx3rgs4r	364	2	randomised	randomised	JJ
cord-017142-vx3rgs4r	364	3	,	,	,
cord-017142-vx3rgs4r	364	4	double	double	JJ
cord-017142-vx3rgs4r	364	5	-	-	HYPH
cord-017142-vx3rgs4r	364	6	blind	blind	JJ
cord-017142-vx3rgs4r	364	7	study	study	NN
cord-017142-vx3rgs4r	364	8	Tumor	tumor	NN
cord-017142-vx3rgs4r	364	9	lysis	lysis	NN
cord-017142-vx3rgs4r	364	10	syndrome	syndrome	NN
cord-017142-vx3rgs4r	364	11	in	in	IN
cord-017142-vx3rgs4r	364	12	a	a	DT
cord-017142-vx3rgs4r	364	13	multiple	multiple	JJ
cord-017142-vx3rgs4r	364	14	myeloma	myeloma	NN
cord-017142-vx3rgs4r	364	15	treated	treat	VBN
cord-017142-vx3rgs4r	364	16	with	with	IN
cord-017142-vx3rgs4r	364	17	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	364	18	Mechanisms	mechanism	NNS
cord-017142-vx3rgs4r	364	19	and	and	CC
cord-017142-vx3rgs4r	364	20	treatment	treatment	NN
cord-017142-vx3rgs4r	364	21	of	of	IN
cord-017142-vx3rgs4r	364	22	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	364	23	of	of	IN
cord-017142-vx3rgs4r	364	24	malignancy	malignancy	NN
cord-017142-vx3rgs4r	364	25	Aggressive	aggressive	JJ
cord-017142-vx3rgs4r	364	26	phase	phase	NN
cord-017142-vx3rgs4r	364	27	of	of	IN
cord-017142-vx3rgs4r	364	28	multiple	multiple	JJ
cord-017142-vx3rgs4r	364	29	myeloma	myeloma	NN
cord-017142-vx3rgs4r	364	30	with	with	IN
cord-017142-vx3rgs4r	364	31	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	364	32	plasma	plasma	NN
cord-017142-vx3rgs4r	364	33	cell	cell	NN
cord-017142-vx3rgs4r	364	34	infiltrates	infiltrate	VBZ
cord-017142-vx3rgs4r	364	35	Selective	selective	JJ
cord-017142-vx3rgs4r	364	36	binding	binding	NN
cord-017142-vx3rgs4r	364	37	of	of	IN
cord-017142-vx3rgs4r	364	38	nifedipine	nifedipine	NN
cord-017142-vx3rgs4r	364	39	to	to	IN
cord-017142-vx3rgs4r	364	40	amyloid	amyloid	NN
cord-017142-vx3rgs4r	364	41	fibrils	fibril	NNS
cord-017142-vx3rgs4r	364	42	Occult	occult	JJ
cord-017142-vx3rgs4r	364	43	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	364	44	haemorrhage	haemorrhage	NN
cord-017142-vx3rgs4r	364	45	in	in	IN
cord-017142-vx3rgs4r	364	46	leukaemia	leukaemia	NN
cord-017142-vx3rgs4r	364	47	Improvement	improvement	NN
cord-017142-vx3rgs4r	364	48	in	in	IN
cord-017142-vx3rgs4r	364	49	renal	renal	JJ
cord-017142-vx3rgs4r	364	50	function	function	NN
cord-017142-vx3rgs4r	364	51	and	and	CC
cord-017142-vx3rgs4r	364	52	its	-PRON-	PRP$
cord-017142-vx3rgs4r	364	53	impact	impact	NN
cord-017142-vx3rgs4r	364	54	on	on	IN
cord-017142-vx3rgs4r	364	55	survival	survival	NN
cord-017142-vx3rgs4r	364	56	in	in	IN
cord-017142-vx3rgs4r	364	57	patients	patient	NNS
cord-017142-vx3rgs4r	364	58	with	with	IN
cord-017142-vx3rgs4r	364	59	newly	newly	RB
cord-017142-vx3rgs4r	364	60	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	364	61	multiple	multiple	JJ
cord-017142-vx3rgs4r	364	62	myeloma	myeloma	NN
cord-017142-vx3rgs4r	364	63	Spinal	spinal	JJ
cord-017142-vx3rgs4r	364	64	cord	cord	NN
cord-017142-vx3rgs4r	364	65	compression	compression	NN
cord-017142-vx3rgs4r	364	66	.	.	.
cord-017142-vx3rgs4r	365	1	In	in	IN
cord-017142-vx3rgs4r	365	2	:	:	:
cord-017142-vx3rgs4r	365	3	Decision	decision	NN
cord-017142-vx3rgs4r	365	4	making	making	NN
cord-017142-vx3rgs4r	365	5	in	in	IN
cord-017142-vx3rgs4r	365	6	medicine	medicine	NN
cord-017142-vx3rgs4r	366	1	A	a	DT
cord-017142-vx3rgs4r	366	2	pilot	pilot	NN
cord-017142-vx3rgs4r	366	3	randomised	randomised	JJ
cord-017142-vx3rgs4r	366	4	comparison	comparison	NN
cord-017142-vx3rgs4r	366	5	of	of	IN
cord-017142-vx3rgs4r	366	6	dexamethasone	dexamethasone	NNP
cord-017142-vx3rgs4r	366	7	96	96	CD
cord-017142-vx3rgs4r	366	8	mg	mg	NNP
cord-017142-vx3rgs4r	366	9	vs	vs	IN
cord-017142-vx3rgs4r	366	10	16	16	CD
cord-017142-vx3rgs4r	366	11	mg	mg	NN
cord-017142-vx3rgs4r	366	12	per	per	IN
cord-017142-vx3rgs4r	366	13	day	day	NN
cord-017142-vx3rgs4r	366	14	for	for	IN
cord-017142-vx3rgs4r	366	15	malignant	malignant	JJ
cord-017142-vx3rgs4r	366	16	spinal	spinal	JJ
cord-017142-vx3rgs4r	366	17	-	-	HYPH
cord-017142-vx3rgs4r	366	18	cord	cord	NN
cord-017142-vx3rgs4r	366	19	compression	compression	NN
cord-017142-vx3rgs4r	366	20	treated	treat	VBN
cord-017142-vx3rgs4r	366	21	by	by	IN
cord-017142-vx3rgs4r	366	22	radiotherapy	radiotherapy	NN
cord-017142-vx3rgs4r	366	23	:	:	:
cord-017142-vx3rgs4r	367	1	TROG	TROG	NNP
cord-017142-vx3rgs4r	367	2	01.05	01.05	CD
cord-017142-vx3rgs4r	368	1	Superdex	Superdex	NNP
cord-017142-vx3rgs4r	368	2	study	study	NN
cord-017142-vx3rgs4r	368	3	Plasmablastic	Plasmablastic	NNP
cord-017142-vx3rgs4r	368	4	morphologyan	morphologyan	NN
cord-017142-vx3rgs4r	368	5	independent	independent	JJ
cord-017142-vx3rgs4r	368	6	prognostic	prognostic	JJ
cord-017142-vx3rgs4r	368	7	factor	factor	NN
cord-017142-vx3rgs4r	368	8	with	with	IN
cord-017142-vx3rgs4r	368	9	clinical	clinical	JJ
cord-017142-vx3rgs4r	368	10	and	and	CC
cord-017142-vx3rgs4r	368	11	laboratory	laboratory	NN
cord-017142-vx3rgs4r	368	12	correlates	correlate	VBZ
cord-017142-vx3rgs4r	368	13	:	:	:
cord-017142-vx3rgs4r	368	14	Eastern	Eastern	NNP
cord-017142-vx3rgs4r	368	15	Cooperative	Cooperative	NNP
cord-017142-vx3rgs4r	368	16	Oncology	Oncology	NNP
cord-017142-vx3rgs4r	368	17	Group	Group	NNP
cord-017142-vx3rgs4r	368	18	(	(	-LRB-
cord-017142-vx3rgs4r	368	19	ECOG	ECOG	NNP
cord-017142-vx3rgs4r	368	20	)	)	-RRB-
cord-017142-vx3rgs4r	368	21	myeloma	myeloma	NN
cord-017142-vx3rgs4r	368	22	trial	trial	NN
cord-017142-vx3rgs4r	368	23	E9486	E9486	NNP
cord-017142-vx3rgs4r	368	24	report	report	NN
cord-017142-vx3rgs4r	368	25	by	by	IN
cord-017142-vx3rgs4r	368	26	the	the	DT
cord-017142-vx3rgs4r	368	27	ECOG	ECOG	NNP
cord-017142-vx3rgs4r	368	28	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	368	29	Laboratory	Laboratory	NNP
cord-017142-vx3rgs4r	368	30	Group	Group	NNP
cord-017142-vx3rgs4r	368	31	Light	Light	NNP
cord-017142-vx3rgs4r	368	32	-	-	HYPH
cord-017142-vx3rgs4r	368	33	chain	chain	NN
cord-017142-vx3rgs4r	368	34	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	368	35	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	368	36	:	:	:
cord-017142-vx3rgs4r	368	37	strategies	strategy	NNS
cord-017142-vx3rgs4r	368	38	to	to	TO
cord-017142-vx3rgs4r	368	39	promote	promote	VB
cord-017142-vx3rgs4r	368	40	early	early	JJ
cord-017142-vx3rgs4r	368	41	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	368	42	and	and	CC
cord-017142-vx3rgs4r	368	43	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	368	44	response	response	NN
cord-017142-vx3rgs4r	368	45	Outcome	outcome	NN
cord-017142-vx3rgs4r	368	46	and	and	CC
cord-017142-vx3rgs4r	368	47	incidence	incidence	NN
cord-017142-vx3rgs4r	368	48	of	of	IN
cord-017142-vx3rgs4r	368	49	appropriate	appropriate	JJ
cord-017142-vx3rgs4r	368	50	implantable	implantable	JJ
cord-017142-vx3rgs4r	368	51	cardioverterdefibrillator	cardioverterdefibrillator	NN
cord-017142-vx3rgs4r	368	52	therapy	therapy	NN
cord-017142-vx3rgs4r	368	53	in	in	IN
cord-017142-vx3rgs4r	368	54	patients	patient	NNS
cord-017142-vx3rgs4r	368	55	with	with	IN
cord-017142-vx3rgs4r	368	56	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	368	57	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	368	58	Hyperviscosity	Hyperviscosity	NNP
cord-017142-vx3rgs4r	368	59	in	in	IN
cord-017142-vx3rgs4r	368	60	plasma	plasma	NN
cord-017142-vx3rgs4r	368	61	cell	cell	NN
cord-017142-vx3rgs4r	368	62	dyscrasias	dyscrasia	NNS
cord-017142-vx3rgs4r	369	1	Randomized	randomized	JJ
cord-017142-vx3rgs4r	369	2	,	,	,
cord-017142-vx3rgs4r	369	3	double	double	JJ
cord-017142-vx3rgs4r	369	4	-	-	HYPH
cord-017142-vx3rgs4r	369	5	blind	blind	JJ
cord-017142-vx3rgs4r	369	6	study	study	NN
cord-017142-vx3rgs4r	369	7	of	of	IN
cord-017142-vx3rgs4r	369	8	denosumab	denosumab	NNP
cord-017142-vx3rgs4r	369	9	versus	versus	IN
cord-017142-vx3rgs4r	369	10	zoledronic	zoledronic	NNP
cord-017142-vx3rgs4r	369	11	acid	acid	NN
cord-017142-vx3rgs4r	369	12	in	in	IN
cord-017142-vx3rgs4r	369	13	the	the	DT
cord-017142-vx3rgs4r	369	14	treatment	treatment	NN
cord-017142-vx3rgs4r	369	15	of	of	IN
cord-017142-vx3rgs4r	369	16	bone	bone	NN
cord-017142-vx3rgs4r	369	17	metastases	metastasis	NNS
cord-017142-vx3rgs4r	369	18	in	in	IN
cord-017142-vx3rgs4r	369	19	patients	patient	NNS
cord-017142-vx3rgs4r	369	20	with	with	IN
cord-017142-vx3rgs4r	369	21	advanced	advanced	JJ
cord-017142-vx3rgs4r	369	22	cancer	cancer	NN
cord-017142-vx3rgs4r	369	23	(	(	-LRB-
cord-017142-vx3rgs4r	369	24	excluding	exclude	VBG
cord-017142-vx3rgs4r	369	25	breast	breast	NN
cord-017142-vx3rgs4r	369	26	and	and	CC
cord-017142-vx3rgs4r	369	27	prostate	prostate	NN
cord-017142-vx3rgs4r	369	28	cancer	cancer	NN
cord-017142-vx3rgs4r	369	29	)	)	-RRB-
cord-017142-vx3rgs4r	369	30	or	or	CC
cord-017142-vx3rgs4r	369	31	multiple	multiple	JJ
cord-017142-vx3rgs4r	369	32	myeloma	myeloma	NN
cord-017142-vx3rgs4r	369	33	Renal	Renal	NNP
cord-017142-vx3rgs4r	369	34	thrombotic	thrombotic	JJ
cord-017142-vx3rgs4r	369	35	microangiopathy	microangiopathy	NNP
cord-017142-vx3rgs4r	369	36	and	and	CC
cord-017142-vx3rgs4r	369	37	podocytopathy	podocytopathy	NNP
cord-017142-vx3rgs4r	369	38	associated	associate	VBN
cord-017142-vx3rgs4r	369	39	with	with	IN
cord-017142-vx3rgs4r	369	40	the	the	DT
cord-017142-vx3rgs4r	369	41	use	use	NN
cord-017142-vx3rgs4r	369	42	of	of	IN
cord-017142-vx3rgs4r	369	43	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	369	44	in	in	IN
cord-017142-vx3rgs4r	369	45	a	a	DT
cord-017142-vx3rgs4r	369	46	patient	patient	NN
cord-017142-vx3rgs4r	369	47	with	with	IN
cord-017142-vx3rgs4r	369	48	multiple	multiple	JJ
cord-017142-vx3rgs4r	369	49	myeloma	myeloma	NN
cord-017142-vx3rgs4r	369	50	Bortezomib	Bortezomib	NNP
cord-017142-vx3rgs4r	369	51	and	and	CC
cord-017142-vx3rgs4r	369	52	heart	heart	NN
cord-017142-vx3rgs4r	369	53	failure	failure	NN
cord-017142-vx3rgs4r	369	54	:	:	:
cord-017142-vx3rgs4r	369	55	case	case	NN
cord-017142-vx3rgs4r	369	56	-	-	HYPH
cord-017142-vx3rgs4r	369	57	report	report	NN
cord-017142-vx3rgs4r	369	58	and	and	CC
cord-017142-vx3rgs4r	369	59	review	review	NN
cord-017142-vx3rgs4r	369	60	of	of	IN
cord-017142-vx3rgs4r	369	61	the	the	DT
cord-017142-vx3rgs4r	369	62	French	French	NNP
cord-017142-vx3rgs4r	369	63	Pharmacovigilance	Pharmacovigilance	NNP
cord-017142-vx3rgs4r	369	64	database	database	NN
cord-017142-vx3rgs4r	369	65	Risk	risk	NN
cord-017142-vx3rgs4r	369	66	of	of	IN
cord-017142-vx3rgs4r	369	67	early	early	JJ
cord-017142-vx3rgs4r	369	68	mortality	mortality	NN
cord-017142-vx3rgs4r	369	69	in	in	IN
cord-017142-vx3rgs4r	369	70	patients	patient	NNS
cord-017142-vx3rgs4r	369	71	with	with	IN
cord-017142-vx3rgs4r	369	72	newly	newly	RB
cord-017142-vx3rgs4r	369	73	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	369	74	multiple	multiple	JJ
cord-017142-vx3rgs4r	369	75	myeloma	myeloma	NN
cord-017142-vx3rgs4r	369	76	Multiple	multiple	JJ
cord-017142-vx3rgs4r	369	77	intraparenchymal	intraparenchymal	JJ
cord-017142-vx3rgs4r	369	78	brain	brain	NN
cord-017142-vx3rgs4r	369	79	plasmacytomas	plasmacytomas	NN
cord-017142-vx3rgs4r	369	80	with	with	IN
cord-017142-vx3rgs4r	369	81	spontaneous	spontaneous	JJ
cord-017142-vx3rgs4r	369	82	intratumoral	intratumoral	JJ
cord-017142-vx3rgs4r	369	83	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	369	84	Treatment	treatment	NN
cord-017142-vx3rgs4r	369	85	of	of	IN
cord-017142-vx3rgs4r	369	86	acute	acute	JJ
cord-017142-vx3rgs4r	369	87	renal	renal	JJ
cord-017142-vx3rgs4r	369	88	failure	failure	NN
cord-017142-vx3rgs4r	369	89	secondary	secondary	JJ
cord-017142-vx3rgs4r	369	90	to	to	IN
cord-017142-vx3rgs4r	369	91	multiple	multiple	JJ
cord-017142-vx3rgs4r	369	92	myeloma	myeloma	NN
cord-017142-vx3rgs4r	369	93	with	with	IN
cord-017142-vx3rgs4r	369	94	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	369	95	and	and	CC
cord-017142-vx3rgs4r	369	96	extended	extend	VBN
cord-017142-vx3rgs4r	369	97	high	high	JJ
cord-017142-vx3rgs4r	369	98	cut	cut	VBN
cord-017142-vx3rgs4r	369	99	-	-	HYPH
cord-017142-vx3rgs4r	369	100	off	off	RP
cord-017142-vx3rgs4r	369	101	hemodialysis	hemodialysis	NN
cord-017142-vx3rgs4r	370	1	The	the	DT
cord-017142-vx3rgs4r	370	2	pathogenesis	pathogenesis	NN
cord-017142-vx3rgs4r	370	3	and	and	CC
cord-017142-vx3rgs4r	370	4	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	370	5	of	of	IN
cord-017142-vx3rgs4r	370	6	acute	acute	JJ
cord-017142-vx3rgs4r	370	7	kidney	kidney	NN
cord-017142-vx3rgs4r	370	8	injury	injury	NN
cord-017142-vx3rgs4r	370	9	in	in	IN
cord-017142-vx3rgs4r	370	10	multiple	multiple	JJ
cord-017142-vx3rgs4r	370	11	myeloma	myeloma	NN
cord-017142-vx3rgs4r	370	12	Early	early	JJ
cord-017142-vx3rgs4r	370	13	reduction	reduction	NN
cord-017142-vx3rgs4r	370	14	of	of	IN
cord-017142-vx3rgs4r	370	15	serum	serum	NN
cord-017142-vx3rgs4r	370	16	-	-	HYPH
cord-017142-vx3rgs4r	370	17	free	free	JJ
cord-017142-vx3rgs4r	370	18	light	light	JJ
cord-017142-vx3rgs4r	370	19	chains	chain	NNS
cord-017142-vx3rgs4r	370	20	associates	associate	NNS
cord-017142-vx3rgs4r	370	21	with	with	IN
cord-017142-vx3rgs4r	370	22	renal	renal	JJ
cord-017142-vx3rgs4r	370	23	recovery	recovery	NN
cord-017142-vx3rgs4r	370	24	in	in	IN
cord-017142-vx3rgs4r	370	25	myeloma	myeloma	NN
cord-017142-vx3rgs4r	370	26	kidney	kidney	NN
cord-017142-vx3rgs4r	370	27	Immunosuppression	Immunosuppression	NNP
cord-017142-vx3rgs4r	370	28	and	and	CC
cord-017142-vx3rgs4r	370	29	infection	infection	NN
cord-017142-vx3rgs4r	370	30	in	in	IN
cord-017142-vx3rgs4r	370	31	multiple	multiple	JJ
cord-017142-vx3rgs4r	370	32	myeloma	myeloma	NN
cord-017142-vx3rgs4r	370	33	Discrimination	discrimination	NN
cord-017142-vx3rgs4r	370	34	of	of	IN
cord-017142-vx3rgs4r	370	35	metastatic	metastatic	NN
cord-017142-vx3rgs4r	370	36	from	from	IN
cord-017142-vx3rgs4r	370	37	acute	acute	JJ
cord-017142-vx3rgs4r	370	38	osteoporotic	osteoporotic	JJ
cord-017142-vx3rgs4r	370	39	compression	compression	NN
cord-017142-vx3rgs4r	370	40	spinal	spinal	JJ
cord-017142-vx3rgs4r	370	41	fractures	fracture	NNS
cord-017142-vx3rgs4r	370	42	with	with	IN
cord-017142-vx3rgs4r	370	43	MR	MR	NNP
cord-017142-vx3rgs4r	370	44	imaging	image	VBG
cord-017142-vx3rgs4r	370	45	Diffuse	Diffuse	NNP
cord-017142-vx3rgs4r	370	46	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	370	47	parenchymal	parenchymal	NN
cord-017142-vx3rgs4r	370	48	involvement	involvement	NN
cord-017142-vx3rgs4r	370	49	in	in	IN
cord-017142-vx3rgs4r	370	50	multiple	multiple	JJ
cord-017142-vx3rgs4r	370	51	myeloma	myeloma	NN
cord-017142-vx3rgs4r	370	52	:	:	:
cord-017142-vx3rgs4r	371	1	antemortem	antemortem	NNP
cord-017142-vx3rgs4r	371	2	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	371	3	Nonspecific	nonspecific	JJ
cord-017142-vx3rgs4r	371	4	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	371	5	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	371	6	after	after	IN
cord-017142-vx3rgs4r	371	7	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	371	8	and	and	CC
cord-017142-vx3rgs4r	371	9	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	371	10	treatment	treatment	NN
cord-017142-vx3rgs4r	371	11	in	in	IN
cord-017142-vx3rgs4r	371	12	a	a	DT
cord-017142-vx3rgs4r	371	13	multiple	multiple	JJ
cord-017142-vx3rgs4r	371	14	myeloma	myeloma	NN
cord-017142-vx3rgs4r	371	15	patient	patient	NN
cord-017142-vx3rgs4r	371	16	Multiple	multiple	JJ
cord-017142-vx3rgs4r	371	17	myeloma	myeloma	NN
cord-017142-vx3rgs4r	371	18	with	with	IN
cord-017142-vx3rgs4r	371	19	myelomatous	myelomatous	JJ
cord-017142-vx3rgs4r	371	20	pleural	pleural	JJ
cord-017142-vx3rgs4r	371	21	effusion	effusion	NN
cord-017142-vx3rgs4r	371	22	:	:	:
cord-017142-vx3rgs4r	371	23	a	a	DT
cord-017142-vx3rgs4r	371	24	case	case	NN
cord-017142-vx3rgs4r	371	25	report	report	NN
cord-017142-vx3rgs4r	371	26	and	and	CC
cord-017142-vx3rgs4r	371	27	review	review	NN
cord-017142-vx3rgs4r	371	28	of	of	IN
cord-017142-vx3rgs4r	371	29	the	the	DT
cord-017142-vx3rgs4r	371	30	literature	literature	NN
cord-017142-vx3rgs4r	371	31	Plasmapheresis	Plasmapheresis	NNP
cord-017142-vx3rgs4r	371	32	in	in	IN
cord-017142-vx3rgs4r	371	33	the	the	DT
cord-017142-vx3rgs4r	371	34	treatment	treatment	NN
cord-017142-vx3rgs4r	371	35	of	of	IN
cord-017142-vx3rgs4r	371	36	renal	renal	JJ
cord-017142-vx3rgs4r	371	37	failure	failure	NN
cord-017142-vx3rgs4r	371	38	associated	associate	VBN
cord-017142-vx3rgs4r	371	39	with	with	IN
cord-017142-vx3rgs4r	371	40	multiple	multiple	JJ
cord-017142-vx3rgs4r	371	41	myeloma	myeloma	NN
cord-017142-vx3rgs4r	371	42	Review	Review	NNP
cord-017142-vx3rgs4r	371	43	of	of	IN
cord-017142-vx3rgs4r	371	44	1027	1027	CD
cord-017142-vx3rgs4r	371	45	patients	patient	NNS
cord-017142-vx3rgs4r	371	46	with	with	IN
cord-017142-vx3rgs4r	371	47	newly	newly	RB
cord-017142-vx3rgs4r	371	48	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	371	49	multiple	multiple	JJ
cord-017142-vx3rgs4r	371	50	myeloma	myeloma	NN
cord-017142-vx3rgs4r	372	1	Salmon	Salmon	NNP
cord-017142-vx3rgs4r	372	2	calcitonin	calcitonin	NN
cord-017142-vx3rgs4r	372	3	in	in	IN
cord-017142-vx3rgs4r	372	4	the	the	DT
cord-017142-vx3rgs4r	372	5	acute	acute	JJ
cord-017142-vx3rgs4r	372	6	management	management	NN
cord-017142-vx3rgs4r	372	7	of	of	IN
cord-017142-vx3rgs4r	372	8	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	373	1	Vertebral	vertebral	JJ
cord-017142-vx3rgs4r	373	2	compression	compression	NN
cord-017142-vx3rgs4r	373	3	fractures	fracture	NNS
cord-017142-vx3rgs4r	373	4	in	in	IN
cord-017142-vx3rgs4r	373	5	multiple	multiple	JJ
cord-017142-vx3rgs4r	373	6	myeloma	myeloma	NN
cord-017142-vx3rgs4r	373	7	Distribution	distribution	NN
cord-017142-vx3rgs4r	373	8	and	and	CC
cord-017142-vx3rgs4r	373	9	appearance	appearance	NN
cord-017142-vx3rgs4r	373	10	at	at	IN
cord-017142-vx3rgs4r	373	11	MR	MR	NNP
cord-017142-vx3rgs4r	373	12	imaging	image	VBG
cord-017142-vx3rgs4r	373	13	Low	low	JJ
cord-017142-vx3rgs4r	373	14	-	-	HYPH
cord-017142-vx3rgs4r	373	15	molecular	molecular	JJ
cord-017142-vx3rgs4r	373	16	-	-	HYPH
cord-017142-vx3rgs4r	373	17	weight	weight	NN
cord-017142-vx3rgs4r	373	18	heparin	heparin	NN
cord-017142-vx3rgs4r	373	19	versus	versus	IN
cord-017142-vx3rgs4r	373	20	a	a	DT
cord-017142-vx3rgs4r	373	21	coumarin	coumarin	NN
cord-017142-vx3rgs4r	373	22	for	for	IN
cord-017142-vx3rgs4r	373	23	the	the	DT
cord-017142-vx3rgs4r	373	24	prevention	prevention	NN
cord-017142-vx3rgs4r	373	25	of	of	IN
cord-017142-vx3rgs4r	373	26	recurrent	recurrent	JJ
cord-017142-vx3rgs4r	373	27	venous	venous	JJ
cord-017142-vx3rgs4r	373	28	thromboembolism	thromboembolism	NN
cord-017142-vx3rgs4r	373	29	in	in	IN
cord-017142-vx3rgs4r	373	30	patients	patient	NNS
cord-017142-vx3rgs4r	373	31	with	with	IN
cord-017142-vx3rgs4r	373	32	cancer	cancer	NN
cord-017142-vx3rgs4r	373	33	Narrative	narrative	NN
cord-017142-vx3rgs4r	373	34	review	review	NN
cord-017142-vx3rgs4r	373	35	:	:	:
cord-017142-vx3rgs4r	374	1	furosemide	furosemide	NN
cord-017142-vx3rgs4r	374	2	for	for	IN
cord-017142-vx3rgs4r	374	3	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	374	4	:	:	:
cord-017142-vx3rgs4r	375	1	an	an	DT
cord-017142-vx3rgs4r	375	2	unproven	unproven	JJ
cord-017142-vx3rgs4r	375	3	yet	yet	CC
cord-017142-vx3rgs4r	375	4	common	common	JJ
cord-017142-vx3rgs4r	375	5	practice	practice	NN
cord-017142-vx3rgs4r	375	6	Use	use	NN
cord-017142-vx3rgs4r	375	7	of	of	IN
cord-017142-vx3rgs4r	375	8	abdominal	abdominal	JJ
cord-017142-vx3rgs4r	375	9	fat	fat	JJ
cord-017142-vx3rgs4r	375	10	tissue	tissue	NN
cord-017142-vx3rgs4r	375	11	aspirate	aspirate	VB
cord-017142-vx3rgs4r	375	12	in	in	IN
cord-017142-vx3rgs4r	375	13	the	the	DT
cord-017142-vx3rgs4r	375	14	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	375	15	of	of	IN
cord-017142-vx3rgs4r	375	16	systemic	systemic	JJ
cord-017142-vx3rgs4r	375	17	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	375	18	Acute	acute	NN
cord-017142-vx3rgs4r	375	19	tubular	tubular	JJ
cord-017142-vx3rgs4r	375	20	necrosis	necrosis	NN
cord-017142-vx3rgs4r	375	21	in	in	IN
cord-017142-vx3rgs4r	375	22	a	a	DT
cord-017142-vx3rgs4r	375	23	patient	patient	NN
cord-017142-vx3rgs4r	375	24	with	with	IN
cord-017142-vx3rgs4r	375	25	myeloma	myeloma	NN
cord-017142-vx3rgs4r	375	26	treated	treat	VBN
cord-017142-vx3rgs4r	375	27	with	with	IN
cord-017142-vx3rgs4r	375	28	carfilzomib	carfilzomib	NNP
cord-017142-vx3rgs4r	375	29	Implantable	implantable	JJ
cord-017142-vx3rgs4r	375	30	cardioverter	cardioverter	JJ
cord-017142-vx3rgs4r	375	31	defibrillators	defibrillator	NNS
cord-017142-vx3rgs4r	375	32	in	in	IN
cord-017142-vx3rgs4r	375	33	patients	patient	NNS
cord-017142-vx3rgs4r	375	34	with	with	IN
cord-017142-vx3rgs4r	375	35	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	375	36	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	376	1	A	a	DT
cord-017142-vx3rgs4r	376	2	2011	2011	CD
cord-017142-vx3rgs4r	376	3	updated	update	VBN
cord-017142-vx3rgs4r	376	4	systematic	systematic	JJ
cord-017142-vx3rgs4r	376	5	review	review	NN
cord-017142-vx3rgs4r	376	6	and	and	CC
cord-017142-vx3rgs4r	376	7	clinical	clinical	JJ
cord-017142-vx3rgs4r	376	8	practice	practice	NN
cord-017142-vx3rgs4r	376	9	guideline	guideline	NN
cord-017142-vx3rgs4r	376	10	for	for	IN
cord-017142-vx3rgs4r	376	11	the	the	DT
cord-017142-vx3rgs4r	376	12	management	management	NN
cord-017142-vx3rgs4r	376	13	of	of	IN
cord-017142-vx3rgs4r	376	14	malignant	malignant	JJ
cord-017142-vx3rgs4r	376	15	extradural	extradural	JJ
cord-017142-vx3rgs4r	376	16	spinal	spinal	JJ
cord-017142-vx3rgs4r	376	17	cord	cord	NN
cord-017142-vx3rgs4r	376	18	compression	compression	NN
cord-017142-vx3rgs4r	376	19	Multiple	multiple	JJ
cord-017142-vx3rgs4r	376	20	myeloma	myeloma	NN
cord-017142-vx3rgs4r	376	21	causing	cause	VBG
cord-017142-vx3rgs4r	376	22	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	376	23	pulmonary	pulmonary	NN
cord-017142-vx3rgs4r	376	24	infiltrates	infiltrate	NNS
cord-017142-vx3rgs4r	376	25	and	and	CC
cord-017142-vx3rgs4r	376	26	softtissue	softtissue	NNP
cord-017142-vx3rgs4r	376	27	plasmacytoma	plasmacytoma	NNP
cord-017142-vx3rgs4r	376	28	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	376	29	in	in	IN
cord-017142-vx3rgs4r	376	30	patients	patient	NNS
cord-017142-vx3rgs4r	376	31	younger	young	JJR
cord-017142-vx3rgs4r	376	32	than	than	IN
cord-017142-vx3rgs4r	376	33	age	age	NN
cord-017142-vx3rgs4r	376	34	50	50	CD
cord-017142-vx3rgs4r	376	35	years	year	NNS
cord-017142-vx3rgs4r	376	36	presents	present	VBZ
cord-017142-vx3rgs4r	376	37	with	with	IN
cord-017142-vx3rgs4r	376	38	more	more	RBR
cord-017142-vx3rgs4r	376	39	favorable	favorable	JJ
cord-017142-vx3rgs4r	376	40	features	feature	NNS
cord-017142-vx3rgs4r	376	41	and	and	CC
cord-017142-vx3rgs4r	376	42	shows	show	VBZ
cord-017142-vx3rgs4r	376	43	better	well	JJR
cord-017142-vx3rgs4r	376	44	survival	survival	NN
cord-017142-vx3rgs4r	376	45	:	:	:
cord-017142-vx3rgs4r	376	46	an	an	DT
cord-017142-vx3rgs4r	376	47	analysis	analysis	NN
cord-017142-vx3rgs4r	376	48	of	of	IN
cord-017142-vx3rgs4r	376	49	10	10	CD
cord-017142-vx3rgs4r	376	50	549	549	CD
cord-017142-vx3rgs4r	376	51	patients	patient	NNS
cord-017142-vx3rgs4r	376	52	from	from	IN
cord-017142-vx3rgs4r	376	53	the	the	DT
cord-017142-vx3rgs4r	376	54	International	International	NNP
cord-017142-vx3rgs4r	376	55	Myeloma	Myeloma	NNP
cord-017142-vx3rgs4r	376	56	Working	Working	NNP
cord-017142-vx3rgs4r	376	57	Group	Group	NNP
cord-017142-vx3rgs4r	376	58	Central	Central	NNP
cord-017142-vx3rgs4r	376	59	nervous	nervous	JJ
cord-017142-vx3rgs4r	376	60	system	system	NN
cord-017142-vx3rgs4r	376	61	involvement	involvement	NN
cord-017142-vx3rgs4r	376	62	in	in	IN
cord-017142-vx3rgs4r	376	63	multiple	multiple	JJ
cord-017142-vx3rgs4r	376	64	myeloma	myeloma	NN
cord-017142-vx3rgs4r	376	65	patients	patient	NNS
cord-017142-vx3rgs4r	376	66	in	in	IN
cord-017142-vx3rgs4r	376	67	the	the	DT
cord-017142-vx3rgs4r	376	68	era	era	NN
cord-017142-vx3rgs4r	376	69	of	of	IN
cord-017142-vx3rgs4r	376	70	novel	novel	JJ
cord-017142-vx3rgs4r	376	71	therapies	therapy	NNS
cord-017142-vx3rgs4r	376	72	(	(	-LRB-
cord-017142-vx3rgs4r	376	73	P07.005	p07.005	NN
cord-017142-vx3rgs4r	376	74	)	)	-RRB-
cord-017142-vx3rgs4r	377	1	Zoledronic	Zoledronic	NNP
cord-017142-vx3rgs4r	377	2	acid	acid	NN
cord-017142-vx3rgs4r	377	3	is	be	VBZ
cord-017142-vx3rgs4r	377	4	superior	superior	JJ
cord-017142-vx3rgs4r	377	5	to	to	TO
cord-017142-vx3rgs4r	377	6	pamidronate	pamidronate	VB
cord-017142-vx3rgs4r	377	7	in	in	IN
cord-017142-vx3rgs4r	377	8	the	the	DT
cord-017142-vx3rgs4r	377	9	treatment	treatment	NN
cord-017142-vx3rgs4r	377	10	of	of	IN
cord-017142-vx3rgs4r	377	11	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	377	12	of	of	IN
cord-017142-vx3rgs4r	377	13	malignancy	malignancy	NN
cord-017142-vx3rgs4r	377	14	:	:	:
cord-017142-vx3rgs4r	378	1	a	a	DT
cord-017142-vx3rgs4r	378	2	pooled	pool	VBN
cord-017142-vx3rgs4r	378	3	analysis	analysis	NN
cord-017142-vx3rgs4r	378	4	of	of	IN
cord-017142-vx3rgs4r	378	5	two	two	CD
cord-017142-vx3rgs4r	378	6	randomized	randomized	JJ
cord-017142-vx3rgs4r	378	7	,	,	,
cord-017142-vx3rgs4r	378	8	controlled	control	VBN
cord-017142-vx3rgs4r	378	9	clinical	clinical	JJ
cord-017142-vx3rgs4r	378	10	trials	trial	NNS
cord-017142-vx3rgs4r	378	11	Effectiveness	Effectiveness	NNP
cord-017142-vx3rgs4r	378	12	of	of	IN
cord-017142-vx3rgs4r	378	13	radiation	radiation	NN
cord-017142-vx3rgs4r	378	14	therapy	therapy	NN
cord-017142-vx3rgs4r	378	15	without	without	IN
cord-017142-vx3rgs4r	378	16	surgery	surgery	NN
cord-017142-vx3rgs4r	378	17	in	in	IN
cord-017142-vx3rgs4r	378	18	metastatic	metastatic	JJ
cord-017142-vx3rgs4r	378	19	spinal	spinal	JJ
cord-017142-vx3rgs4r	378	20	cord	cord	NN
cord-017142-vx3rgs4r	378	21	compression	compression	NN
cord-017142-vx3rgs4r	378	22	:	:	:
cord-017142-vx3rgs4r	378	23	final	final	JJ
cord-017142-vx3rgs4r	378	24	results	result	NNS
cord-017142-vx3rgs4r	378	25	from	from	IN
cord-017142-vx3rgs4r	378	26	a	a	DT
cord-017142-vx3rgs4r	378	27	prospective	prospective	JJ
cord-017142-vx3rgs4r	378	28	trial	trial	NN
cord-017142-vx3rgs4r	378	29	Multiple	multiple	JJ
cord-017142-vx3rgs4r	378	30	myeloma	myeloma	NN
cord-017142-vx3rgs4r	378	31	invasion	invasion	NN
cord-017142-vx3rgs4r	378	32	of	of	IN
cord-017142-vx3rgs4r	378	33	the	the	DT
cord-017142-vx3rgs4r	378	34	central	central	JJ
cord-017142-vx3rgs4r	378	35	nervous	nervous	JJ
cord-017142-vx3rgs4r	378	36	system	system	NN
cord-017142-vx3rgs4r	378	37	Proliferative	Proliferative	NNP
cord-017142-vx3rgs4r	378	38	activity	activity	NN
cord-017142-vx3rgs4r	378	39	of	of	IN
cord-017142-vx3rgs4r	378	40	myeloma	myeloma	NN
cord-017142-vx3rgs4r	378	41	cells	cell	NNS
cord-017142-vx3rgs4r	378	42	determined	determine	VBN
cord-017142-vx3rgs4r	378	43	by	by	IN
cord-017142-vx3rgs4r	378	44	Ki-67	Ki-67	NNP
cord-017142-vx3rgs4r	378	45	antibody	antibody	NN
cord-017142-vx3rgs4r	378	46	:	:	:
cord-017142-vx3rgs4r	378	47	biological	biological	JJ
cord-017142-vx3rgs4r	378	48	and	and	CC
cord-017142-vx3rgs4r	378	49	clinical	clinical	JJ
cord-017142-vx3rgs4r	378	50	significance	significance	NN
cord-017142-vx3rgs4r	379	1	Acute	acute	JJ
cord-017142-vx3rgs4r	379	2	respiratory	respiratory	JJ
cord-017142-vx3rgs4r	379	3	distress	distress	NN
cord-017142-vx3rgs4r	379	4	syndrome	syndrome	NN
cord-017142-vx3rgs4r	379	5	due	due	IN
cord-017142-vx3rgs4r	379	6	to	to	IN
cord-017142-vx3rgs4r	379	7	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	379	8	involvement	involvement	NN
cord-017142-vx3rgs4r	379	9	by	by	IN
cord-017142-vx3rgs4r	379	10	neoplastic	neoplastic	JJ
cord-017142-vx3rgs4r	379	11	plasma	plasma	NN
cord-017142-vx3rgs4r	379	12	cells	cell	NNS
cord-017142-vx3rgs4r	379	13	in	in	IN
cord-017142-vx3rgs4r	379	14	multiple	multiple	JJ
cord-017142-vx3rgs4r	379	15	myeloma	myeloma	NN
cord-017142-vx3rgs4r	379	16	Hyperviscosity	Hyperviscosity	NNP
cord-017142-vx3rgs4r	379	17	syndrome	syndrome	NN
cord-017142-vx3rgs4r	379	18	in	in	IN
cord-017142-vx3rgs4r	379	19	plasma	plasma	NN
cord-017142-vx3rgs4r	379	20	cell	cell	NN
cord-017142-vx3rgs4r	379	21	dyscrasias	dyscrasias	NNP
cord-017142-vx3rgs4r	379	22	Acute	acute	JJ
cord-017142-vx3rgs4r	379	23	pancreatitis	pancreatitis	NN
cord-017142-vx3rgs4r	379	24	secondary	secondary	JJ
cord-017142-vx3rgs4r	379	25	to	to	IN
cord-017142-vx3rgs4r	379	26	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	379	27	of	of	IN
cord-017142-vx3rgs4r	379	28	multiple	multiple	JJ
cord-017142-vx3rgs4r	379	29	myeloma	myeloma	NN
cord-017142-vx3rgs4r	379	30	Effect	effect	NN
cord-017142-vx3rgs4r	379	31	of	of	IN
cord-017142-vx3rgs4r	379	32	plasmapheresis	plasmapheresis	NN
cord-017142-vx3rgs4r	379	33	on	on	IN
cord-017142-vx3rgs4r	379	34	hyperviscosity	hyperviscosity	NN
cord-017142-vx3rgs4r	379	35	-	-	HYPH
cord-017142-vx3rgs4r	379	36	related	relate	VBN
cord-017142-vx3rgs4r	379	37	retinopathy	retinopathy	NN
cord-017142-vx3rgs4r	379	38	and	and	CC
cord-017142-vx3rgs4r	379	39	retinal	retinal	JJ
cord-017142-vx3rgs4r	379	40	hemodynamics	hemodynamic	NNS
cord-017142-vx3rgs4r	379	41	in	in	IN
cord-017142-vx3rgs4r	379	42	patients	patient	NNS
cord-017142-vx3rgs4r	379	43	with	with	IN
cord-017142-vx3rgs4r	379	44	Waldenstrom	Waldenstrom	NNP
cord-017142-vx3rgs4r	379	45	's	's	POS
cord-017142-vx3rgs4r	379	46	macroglobulinemia	macroglobulinemia	JJ
cord-017142-vx3rgs4r	379	47	Cardiac	Cardiac	NNP
cord-017142-vx3rgs4r	379	48	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	379	49	and	and	CC
cord-017142-vx3rgs4r	379	50	its	-PRON-	PRP$
cord-017142-vx3rgs4r	379	51	new	new	JJ
cord-017142-vx3rgs4r	379	52	clinical	clinical	JJ
cord-017142-vx3rgs4r	379	53	phenotype	phenotype	NN
cord-017142-vx3rgs4r	379	54	:	:	:
cord-017142-vx3rgs4r	379	55	heart	heart	NN
cord-017142-vx3rgs4r	379	56	failure	failure	NN
cord-017142-vx3rgs4r	379	57	with	with	IN
cord-017142-vx3rgs4r	379	58	preserved	preserve	VBN
cord-017142-vx3rgs4r	379	59	ejection	ejection	NN
cord-017142-vx3rgs4r	379	60	fraction	fraction	NN
cord-017142-vx3rgs4r	379	61	Corticosteroids	Corticosteroids	NNPS
cord-017142-vx3rgs4r	379	62	as	as	IN
cord-017142-vx3rgs4r	379	63	adjunctive	adjunctive	JJ
cord-017142-vx3rgs4r	379	64	therapy	therapy	NN
cord-017142-vx3rgs4r	379	65	for	for	IN
cord-017142-vx3rgs4r	379	66	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	379	67	alveolar	alveolar	JJ
cord-017142-vx3rgs4r	379	68	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	379	69	associated	associate	VBN
cord-017142-vx3rgs4r	379	70	with	with	IN
cord-017142-vx3rgs4r	379	71	bone	bone	NN
cord-017142-vx3rgs4r	379	72	marrow	marrow	NN
cord-017142-vx3rgs4r	379	73	transplantation	transplantation	NN
cord-017142-vx3rgs4r	379	74	Acute	acute	JJ
cord-017142-vx3rgs4r	379	75	tachypnea	tachypnea	NN
cord-017142-vx3rgs4r	379	76	during	during	IN
cord-017142-vx3rgs4r	379	77	mechanical	mechanical	JJ
cord-017142-vx3rgs4r	379	78	ventilation	ventilation	NN
cord-017142-vx3rgs4r	379	79	in	in	IN
cord-017142-vx3rgs4r	379	80	a	a	DT
cord-017142-vx3rgs4r	379	81	62-year	62-year	JJ
cord-017142-vx3rgs4r	379	82	-	-	HYPH
cord-017142-vx3rgs4r	379	83	old	old	JJ
cord-017142-vx3rgs4r	379	84	man	man	NN
cord-017142-vx3rgs4r	379	85	with	with	IN
cord-017142-vx3rgs4r	379	86	multiple	multiple	JJ
cord-017142-vx3rgs4r	379	87	myeloma	myeloma	NN
cord-017142-vx3rgs4r	379	88	involving	involve	VBG
cord-017142-vx3rgs4r	379	89	the	the	DT
cord-017142-vx3rgs4r	379	90	spinal	spinal	JJ
cord-017142-vx3rgs4r	379	91	cord	cord	NN
cord-017142-vx3rgs4r	379	92	Optimizing	optimize	VBG
cord-017142-vx3rgs4r	379	93	the	the	DT
cord-017142-vx3rgs4r	379	94	management	management	NN
cord-017142-vx3rgs4r	379	95	of	of	IN
cord-017142-vx3rgs4r	379	96	patients	patient	NNS
cord-017142-vx3rgs4r	379	97	with	with	IN
cord-017142-vx3rgs4r	379	98	spinal	spinal	JJ
cord-017142-vx3rgs4r	379	99	myeloma	myeloma	NN
cord-017142-vx3rgs4r	379	100	disease	disease	NN
cord-017142-vx3rgs4r	379	101	Risk	risk	NN
cord-017142-vx3rgs4r	379	102	factors	factor	NNS
cord-017142-vx3rgs4r	379	103	for	for	IN
cord-017142-vx3rgs4r	379	104	early	early	JJ
cord-017142-vx3rgs4r	379	105	death	death	NN
cord-017142-vx3rgs4r	379	106	in	in	IN
cord-017142-vx3rgs4r	379	107	patients	patient	NNS
cord-017142-vx3rgs4r	379	108	undergoing	undergo	VBG
cord-017142-vx3rgs4r	379	109	treatment	treatment	NN
cord-017142-vx3rgs4r	379	110	for	for	IN
cord-017142-vx3rgs4r	379	111	multiple	multiple	JJ
cord-017142-vx3rgs4r	379	112	myeloma	myeloma	NN
cord-017142-vx3rgs4r	380	1	Prophylactic	prophylactic	JJ
cord-017142-vx3rgs4r	380	2	low	low	JJ
cord-017142-vx3rgs4r	380	3	-	-	HYPH
cord-017142-vx3rgs4r	380	4	dose	dose	NN
cord-017142-vx3rgs4r	380	5	aspirin	aspirin	NN
cord-017142-vx3rgs4r	380	6	is	be	VBZ
cord-017142-vx3rgs4r	380	7	effective	effective	JJ
cord-017142-vx3rgs4r	380	8	antithrombotic	antithrombotic	JJ
cord-017142-vx3rgs4r	380	9	therapy	therapy	NN
cord-017142-vx3rgs4r	380	10	for	for	IN
cord-017142-vx3rgs4r	380	11	combination	combination	NN
cord-017142-vx3rgs4r	380	12	treatments	treatment	NNS
cord-017142-vx3rgs4r	380	13	of	of	IN
cord-017142-vx3rgs4r	380	14	thalidomide	thalidomide	NN
cord-017142-vx3rgs4r	380	15	or	or	CC
cord-017142-vx3rgs4r	380	16	lenalidomide	lenalidomide	NN
cord-017142-vx3rgs4r	380	17	in	in	IN
cord-017142-vx3rgs4r	380	18	myeloma	myeloma	NN
cord-017142-vx3rgs4r	381	1	Is	be	VBZ
cord-017142-vx3rgs4r	381	2	elevated	elevate	VBN
cord-017142-vx3rgs4r	381	3	plasma	plasma	NN
cord-017142-vx3rgs4r	381	4	B	b	NN
cord-017142-vx3rgs4r	381	5	-	-	HYPH
cord-017142-vx3rgs4r	381	6	natriuretic	natriuretic	NN
cord-017142-vx3rgs4r	381	7	peptide	peptide	NN
cord-017142-vx3rgs4r	381	8	in	in	IN
cord-017142-vx3rgs4r	381	9	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	381	10	simply	simply	RB
cord-017142-vx3rgs4r	381	11	a	a	DT
cord-017142-vx3rgs4r	381	12	function	function	NN
cord-017142-vx3rgs4r	381	13	of	of	IN
cord-017142-vx3rgs4r	381	14	the	the	DT
cord-017142-vx3rgs4r	381	15	presence	presence	NN
cord-017142-vx3rgs4r	381	16	of	of	IN
cord-017142-vx3rgs4r	381	17	heart	heart	NN
cord-017142-vx3rgs4r	381	18	failure	failure	NN
cord-017142-vx3rgs4r	381	19	?	?	.
cord-017142-vx3rgs4r	382	1	Infections	infection	NNS
cord-017142-vx3rgs4r	382	2	in	in	IN
cord-017142-vx3rgs4r	382	3	patients	patient	NNS
cord-017142-vx3rgs4r	382	4	with	with	IN
cord-017142-vx3rgs4r	382	5	multiple	multiple	JJ
cord-017142-vx3rgs4r	382	6	myeloma	myeloma	NN
cord-017142-vx3rgs4r	382	7	in	in	IN
cord-017142-vx3rgs4r	382	8	the	the	DT
cord-017142-vx3rgs4r	382	9	era	era	NN
cord-017142-vx3rgs4r	382	10	of	of	IN
cord-017142-vx3rgs4r	382	11	high	high	JJ
cord-017142-vx3rgs4r	382	12	-	-	HYPH
cord-017142-vx3rgs4r	382	13	dose	dose	NN
cord-017142-vx3rgs4r	382	14	therapy	therapy	NN
cord-017142-vx3rgs4r	382	15	and	and	CC
cord-017142-vx3rgs4r	382	16	novel	novel	NN
cord-017142-vx3rgs4r	382	17	agents	agent	NNS
cord-017142-vx3rgs4r	382	18	Unexpected	unexpected	JJ
cord-017142-vx3rgs4r	382	19	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	382	20	in	in	IN
cord-017142-vx3rgs4r	382	21	haematological	haematological	NNP
cord-017142-vx3rgs4r	382	22	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	382	23	treated	treat	VBD
cord-017142-vx3rgs4r	382	24	patients	patient	NNS
cord-017142-vx3rgs4r	382	25	Phase	Phase	NNP
cord-017142-vx3rgs4r	383	1	I	-PRON-	PRP
cord-017142-vx3rgs4r	383	2	trial	trial	NN
cord-017142-vx3rgs4r	383	3	of	of	IN
cord-017142-vx3rgs4r	383	4	the	the	DT
cord-017142-vx3rgs4r	383	5	proteasome	proteasome	VBN
cord-017142-vx3rgs4r	383	6	inhibitor	inhibitor	NN
cord-017142-vx3rgs4r	383	7	bortezomib	bortezomib	NN
cord-017142-vx3rgs4r	383	8	in	in	IN
cord-017142-vx3rgs4r	383	9	patients	patient	NNS
cord-017142-vx3rgs4r	383	10	with	with	IN
cord-017142-vx3rgs4r	383	11	advanced	advanced	JJ
cord-017142-vx3rgs4r	383	12	solid	solid	JJ
cord-017142-vx3rgs4r	383	13	tumors	tumor	NNS
cord-017142-vx3rgs4r	383	14	with	with	IN
cord-017142-vx3rgs4r	383	15	observations	observation	NNS
cord-017142-vx3rgs4r	383	16	in	in	IN
cord-017142-vx3rgs4r	383	17	androgenindependent	androgenindependent	NN
cord-017142-vx3rgs4r	383	18	prostate	prostate	NN
cord-017142-vx3rgs4r	383	19	cancer	cancer	NN
cord-017142-vx3rgs4r	383	20	Cerebral	Cerebral	NNP
cord-017142-vx3rgs4r	383	21	infarction	infarction	NN
cord-017142-vx3rgs4r	383	22	in	in	IN
cord-017142-vx3rgs4r	383	23	IgG	IgG	NNP
cord-017142-vx3rgs4r	383	24	multiple	multiple	JJ
cord-017142-vx3rgs4r	383	25	myeloma	myeloma	NN
cord-017142-vx3rgs4r	383	26	with	with	IN
cord-017142-vx3rgs4r	383	27	hyperviscosity	hyperviscosity	NNP
cord-017142-vx3rgs4r	383	28	Meningeal	Meningeal	NNP
cord-017142-vx3rgs4r	383	29	and	and	CC
cord-017142-vx3rgs4r	383	30	cerebral	cerebral	JJ
cord-017142-vx3rgs4r	383	31	involvement	involvement	NN
cord-017142-vx3rgs4r	383	32	in	in	IN
cord-017142-vx3rgs4r	383	33	multiple	multiple	JJ
cord-017142-vx3rgs4r	383	34	myeloma	myeloma	NN
cord-017142-vx3rgs4r	383	35	patients	patient	NNS
cord-017142-vx3rgs4r	384	1	Randomized	randomized	JJ
cord-017142-vx3rgs4r	384	2	phase	phase	NN
cord-017142-vx3rgs4r	384	3	II	II	NNP
cord-017142-vx3rgs4r	384	4	trial	trial	NN
cord-017142-vx3rgs4r	384	5	comparing	compare	VBG
cord-017142-vx3rgs4r	384	6	different	different	JJ
cord-017142-vx3rgs4r	384	7	doses	dose	NNS
cord-017142-vx3rgs4r	384	8	of	of	IN
cord-017142-vx3rgs4r	384	9	the	the	DT
cord-017142-vx3rgs4r	384	10	bisphosphonate	bisphosphonate	NNP
cord-017142-vx3rgs4r	384	11	ibandronate	ibandronate	NNP
cord-017142-vx3rgs4r	384	12	in	in	IN
cord-017142-vx3rgs4r	384	13	the	the	DT
cord-017142-vx3rgs4r	384	14	treatment	treatment	NN
cord-017142-vx3rgs4r	384	15	of	of	IN
cord-017142-vx3rgs4r	384	16	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	384	17	of	of	IN
cord-017142-vx3rgs4r	384	18	malignancy	malignancy	NN
cord-017142-vx3rgs4r	384	19	Efficacy	Efficacy	NNP
cord-017142-vx3rgs4r	384	20	and	and	CC
cord-017142-vx3rgs4r	384	21	safety	safety	NN
cord-017142-vx3rgs4r	384	22	of	of	IN
cord-017142-vx3rgs4r	384	23	ibandronate	ibandronate	NN
cord-017142-vx3rgs4r	384	24	in	in	IN
cord-017142-vx3rgs4r	384	25	the	the	DT
cord-017142-vx3rgs4r	384	26	treatment	treatment	NN
cord-017142-vx3rgs4r	384	27	of	of	IN
cord-017142-vx3rgs4r	384	28	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	384	29	of	of	IN
cord-017142-vx3rgs4r	384	30	malignancy	malignancy	NN
cord-017142-vx3rgs4r	384	31	:	:	:
cord-017142-vx3rgs4r	384	32	a	a	DT
cord-017142-vx3rgs4r	384	33	randomized	randomized	JJ
cord-017142-vx3rgs4r	384	34	multicentric	multicentric	JJ
cord-017142-vx3rgs4r	384	35	comparison	comparison	NN
cord-017142-vx3rgs4r	384	36	to	to	TO
cord-017142-vx3rgs4r	384	37	pamidronate	pamidronate	VB
cord-017142-vx3rgs4r	384	38	Continued	continued	JJ
cord-017142-vx3rgs4r	384	39	survival	survival	NN
cord-017142-vx3rgs4r	384	40	gains	gain	NNS
cord-017142-vx3rgs4r	384	41	in	in	IN
cord-017142-vx3rgs4r	384	42	recent	recent	JJ
cord-017142-vx3rgs4r	384	43	years	year	NNS
cord-017142-vx3rgs4r	384	44	among	among	IN
cord-017142-vx3rgs4r	384	45	critically	critically	RB
cord-017142-vx3rgs4r	384	46	ill	ill	JJ
cord-017142-vx3rgs4r	384	47	myeloma	myeloma	NN
cord-017142-vx3rgs4r	384	48	patients	patient	NNS
cord-017142-vx3rgs4r	385	1	Acute	acute	JJ
cord-017142-vx3rgs4r	385	2	respiratory	respiratory	JJ
cord-017142-vx3rgs4r	385	3	distress	distress	NN
cord-017142-vx3rgs4r	385	4	syndrome	syndrome	NN
cord-017142-vx3rgs4r	385	5	with	with	IN
cord-017142-vx3rgs4r	385	6	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	385	7	calcification	calcification	NN
cord-017142-vx3rgs4r	385	8	in	in	IN
cord-017142-vx3rgs4r	385	9	two	two	CD
cord-017142-vx3rgs4r	385	10	patients	patient	NNS
cord-017142-vx3rgs4r	385	11	with	with	IN
cord-017142-vx3rgs4r	385	12	B	b	NN
cord-017142-vx3rgs4r	385	13	cell	cell	NN
cord-017142-vx3rgs4r	385	14	malignancies	malignancy	NNS
cord-017142-vx3rgs4r	385	15	Immunodeficiency	immunodeficiency	NN
cord-017142-vx3rgs4r	385	16	and	and	CC
cord-017142-vx3rgs4r	385	17	immunotherapy	immunotherapy	NN
cord-017142-vx3rgs4r	385	18	in	in	IN
cord-017142-vx3rgs4r	385	19	multiple	multiple	JJ
cord-017142-vx3rgs4r	385	20	myeloma	myeloma	NN
cord-017142-vx3rgs4r	386	1	Is	be	VBZ
cord-017142-vx3rgs4r	386	2	surgery	surgery	NN
cord-017142-vx3rgs4r	386	3	required	require	VBN
cord-017142-vx3rgs4r	386	4	in	in	IN
cord-017142-vx3rgs4r	386	5	the	the	DT
cord-017142-vx3rgs4r	386	6	management	management	NN
cord-017142-vx3rgs4r	386	7	of	of	IN
cord-017142-vx3rgs4r	386	8	spinal	spinal	JJ
cord-017142-vx3rgs4r	386	9	cord	cord	NN
cord-017142-vx3rgs4r	386	10	compression	compression	NN
cord-017142-vx3rgs4r	386	11	in	in	IN
cord-017142-vx3rgs4r	386	12	myeloma	myeloma	NN
cord-017142-vx3rgs4r	386	13	patients	patient	NNS
cord-017142-vx3rgs4r	386	14	?	?	.
cord-017142-vx3rgs4r	387	1	Carfilzomib	Carfilzomib	NNP
cord-017142-vx3rgs4r	387	2	:	:	:
cord-017142-vx3rgs4r	388	1	a	a	DT
cord-017142-vx3rgs4r	388	2	cause	cause	NN
cord-017142-vx3rgs4r	388	3	of	of	IN
cord-017142-vx3rgs4r	388	4	drug	drug	NN
cord-017142-vx3rgs4r	388	5	induced	induce	VBN
cord-017142-vx3rgs4r	388	6	thrombotic	thrombotic	JJ
cord-017142-vx3rgs4r	388	7	microangiopathy	microangiopathy	NNP
cord-017142-vx3rgs4r	388	8	Final	final	JJ
cord-017142-vx3rgs4r	388	9	results	result	NNS
cord-017142-vx3rgs4r	388	10	of	of	IN
cord-017142-vx3rgs4r	388	11	a	a	DT
cord-017142-vx3rgs4r	388	12	prospective	prospective	JJ
cord-017142-vx3rgs4r	388	13	study	study	NN
cord-017142-vx3rgs4r	388	14	of	of	IN
cord-017142-vx3rgs4r	388	15	the	the	DT
cord-017142-vx3rgs4r	388	16	prognostic	prognostic	JJ
cord-017142-vx3rgs4r	388	17	value	value	NN
cord-017142-vx3rgs4r	388	18	of	of	IN
cord-017142-vx3rgs4r	388	19	the	the	DT
cord-017142-vx3rgs4r	388	20	time	time	NN
cord-017142-vx3rgs4r	388	21	to	to	TO
cord-017142-vx3rgs4r	388	22	develop	develop	VB
cord-017142-vx3rgs4r	388	23	motor	motor	NN
cord-017142-vx3rgs4r	388	24	deficits	deficit	NNS
cord-017142-vx3rgs4r	388	25	before	before	IN
cord-017142-vx3rgs4r	388	26	irradiation	irradiation	NN
cord-017142-vx3rgs4r	388	27	in	in	IN
cord-017142-vx3rgs4r	388	28	metastatic	metastatic	JJ
cord-017142-vx3rgs4r	388	29	spinal	spinal	JJ
cord-017142-vx3rgs4r	388	30	cord	cord	NN
cord-017142-vx3rgs4r	388	31	compression	compression	NN
cord-017142-vx3rgs4r	388	32	Outcome	outcome	NN
cord-017142-vx3rgs4r	388	33	after	after	IN
cord-017142-vx3rgs4r	388	34	radiotherapy	radiotherapy	NN
cord-017142-vx3rgs4r	388	35	alone	alone	RB
cord-017142-vx3rgs4r	388	36	for	for	IN
cord-017142-vx3rgs4r	388	37	metastatic	metastatic	JJ
cord-017142-vx3rgs4r	388	38	spinal	spinal	JJ
cord-017142-vx3rgs4r	388	39	cord	cord	NN
cord-017142-vx3rgs4r	388	40	compression	compression	NN
cord-017142-vx3rgs4r	388	41	in	in	IN
cord-017142-vx3rgs4r	388	42	patients	patient	NNS
cord-017142-vx3rgs4r	388	43	with	with	IN
cord-017142-vx3rgs4r	388	44	oligometastases	oligometastase	NNS
cord-017142-vx3rgs4r	389	1	Low-	low-	NN
cord-017142-vx3rgs4r	389	2	,	,	,
cord-017142-vx3rgs4r	389	3	medium	medium	NN
cord-017142-vx3rgs4r	389	4	-	-	HYPH
cord-017142-vx3rgs4r	389	5	and	and	CC
cord-017142-vx3rgs4r	389	6	highdose	highdose	NN
cord-017142-vx3rgs4r	389	7	steroids	steroid	NNS
cord-017142-vx3rgs4r	389	8	with	with	IN
cord-017142-vx3rgs4r	389	9	or	or	CC
cord-017142-vx3rgs4r	389	10	without	without	IN
cord-017142-vx3rgs4r	389	11	aminocaproic	aminocaproic	NN
cord-017142-vx3rgs4r	389	12	acid	acid	NN
cord-017142-vx3rgs4r	389	13	in	in	IN
cord-017142-vx3rgs4r	389	14	adult	adult	NN
cord-017142-vx3rgs4r	389	15	hematopoietic	hematopoietic	JJ
cord-017142-vx3rgs4r	389	16	SCT	SCT	NNP
cord-017142-vx3rgs4r	389	17	patients	patient	NNS
cord-017142-vx3rgs4r	389	18	with	with	IN
cord-017142-vx3rgs4r	389	19	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	389	20	alveolar	alveolar	NN
cord-017142-vx3rgs4r	389	21	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	389	22	Lung	lung	NN
cord-017142-vx3rgs4r	389	23	postmortem	postmortem	NN
cord-017142-vx3rgs4r	389	24	autopsy	autopsy	JJ
cord-017142-vx3rgs4r	389	25	revealing	reveal	VBG
cord-017142-vx3rgs4r	389	26	extramedullary	extramedullary	JJ
cord-017142-vx3rgs4r	389	27	involvement	involvement	NN
cord-017142-vx3rgs4r	389	28	in	in	IN
cord-017142-vx3rgs4r	389	29	multiple	multiple	JJ
cord-017142-vx3rgs4r	389	30	myeloma	myeloma	NN
cord-017142-vx3rgs4r	389	31	causing	cause	VBG
cord-017142-vx3rgs4r	389	32	acute	acute	JJ
cord-017142-vx3rgs4r	389	33	respiratory	respiratory	JJ
cord-017142-vx3rgs4r	389	34	distress	distress	NN
cord-017142-vx3rgs4r	389	35	syndrome	syndrome	NN
cord-017142-vx3rgs4r	389	36	Digoxin	digoxin	JJ
cord-017142-vx3rgs4r	389	37	sensitivity	sensitivity	NN
cord-017142-vx3rgs4r	389	38	in	in	IN
cord-017142-vx3rgs4r	389	39	amyloid	amyloid	NN
cord-017142-vx3rgs4r	389	40	cardiomyopathy	cardiomyopathy	NN
cord-017142-vx3rgs4r	389	41	O039	O039	NNP
cord-017142-vx3rgs4r	389	42	Dialysis	Dialysis	NNP
cord-017142-vx3rgs4r	389	43	with	with	IN
cord-017142-vx3rgs4r	389	44	HCO	HCO	NNP
cord-017142-vx3rgs4r	389	45	membrane	membrane	NN
cord-017142-vx3rgs4r	389	46	in	in	IN
cord-017142-vx3rgs4r	389	47	combination	combination	NN
cord-017142-vx3rgs4r	389	48	with	with	IN
cord-017142-vx3rgs4r	389	49	potent	potent	JJ
cord-017142-vx3rgs4r	389	50	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	389	51	increases	increase	VBZ
cord-017142-vx3rgs4r	389	52	the	the	DT
cord-017142-vx3rgs4r	389	53	probability	probability	NN
cord-017142-vx3rgs4r	389	54	for	for	IN
cord-017142-vx3rgs4r	389	55	renal	renal	JJ
cord-017142-vx3rgs4r	389	56	recovery	recovery	NN
cord-017142-vx3rgs4r	389	57	and	and	CC
cord-017142-vx3rgs4r	389	58	better	well	JJR
cord-017142-vx3rgs4r	389	59	survival	survival	NN
cord-017142-vx3rgs4r	389	60	in	in	IN
cord-017142-vx3rgs4r	389	61	patients	patient	NNS
cord-017142-vx3rgs4r	389	62	with	with	IN
cord-017142-vx3rgs4r	389	63	acute	acute	JJ
cord-017142-vx3rgs4r	389	64	renal	renal	JJ
cord-017142-vx3rgs4r	389	65	failure	failure	NN
cord-017142-vx3rgs4r	389	66	due	due	IN
cord-017142-vx3rgs4r	389	67	to	to	IN
cord-017142-vx3rgs4r	389	68	myeloma	myeloma	NN
cord-017142-vx3rgs4r	389	69	kidney	kidney	NN
cord-017142-vx3rgs4r	389	70	-	-	HYPH
cord-017142-vx3rgs4r	389	71	data	datum	NNS
cord-017142-vx3rgs4r	389	72	from	from	IN
cord-017142-vx3rgs4r	389	73	Biphasic	Biphasic	NNP
cord-017142-vx3rgs4r	389	74	pattern	pattern	NN
cord-017142-vx3rgs4r	389	75	of	of	IN
cord-017142-vx3rgs4r	389	76	bacterial	bacterial	JJ
cord-017142-vx3rgs4r	389	77	infection	infection	NN
cord-017142-vx3rgs4r	389	78	in	in	IN
cord-017142-vx3rgs4r	389	79	multiple	multiple	JJ
cord-017142-vx3rgs4r	389	80	myeloma	myeloma	NN
cord-017142-vx3rgs4r	389	81	Guidelines	guideline	NNS
cord-017142-vx3rgs4r	389	82	on	on	IN
cord-017142-vx3rgs4r	389	83	the	the	DT
cord-017142-vx3rgs4r	389	84	use	use	NN
cord-017142-vx3rgs4r	389	85	of	of	IN
cord-017142-vx3rgs4r	389	86	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	389	87	apheresis	apheresis	NN
cord-017142-vx3rgs4r	389	88	in	in	IN
cord-017142-vx3rgs4r	389	89	clinical	clinical	JJ
cord-017142-vx3rgs4r	389	90	practiceevidence	practiceevidence	NN
cord-017142-vx3rgs4r	389	91	-	-	HYPH
cord-017142-vx3rgs4r	389	92	based	base	VBN
cord-017142-vx3rgs4r	389	93	approach	approach	NN
cord-017142-vx3rgs4r	389	94	from	from	IN
cord-017142-vx3rgs4r	389	95	the	the	DT
cord-017142-vx3rgs4r	389	96	Writing	Writing	NNP
cord-017142-vx3rgs4r	389	97	Committee	Committee	NNP
cord-017142-vx3rgs4r	389	98	of	of	IN
cord-017142-vx3rgs4r	389	99	the	the	DT
cord-017142-vx3rgs4r	389	100	American	American	NNP
cord-017142-vx3rgs4r	389	101	Society	Society	NNP
cord-017142-vx3rgs4r	389	102	for	for	IN
cord-017142-vx3rgs4r	389	103	Apheresis	Apheresis	NNP
cord-017142-vx3rgs4r	389	104	:	:	:
cord-017142-vx3rgs4r	390	1	the	the	DT
cord-017142-vx3rgs4r	390	2	seventh	seventh	JJ
cord-017142-vx3rgs4r	390	3	special	special	JJ
cord-017142-vx3rgs4r	390	4	issue	issue	NN
cord-017142-vx3rgs4r	390	5	Combination	combination	NN
cord-017142-vx3rgs4r	390	6	of	of	IN
cord-017142-vx3rgs4r	390	7	calcitonin	calcitonin	NN
cord-017142-vx3rgs4r	390	8	and	and	CC
cord-017142-vx3rgs4r	390	9	pamidronate	pamidronate	NN
cord-017142-vx3rgs4r	390	10	for	for	IN
cord-017142-vx3rgs4r	390	11	emergency	emergency	NN
cord-017142-vx3rgs4r	390	12	treatment	treatment	NN
cord-017142-vx3rgs4r	390	13	of	of	IN
cord-017142-vx3rgs4r	390	14	malignant	malignant	JJ
cord-017142-vx3rgs4r	390	15	hypercalcemia	hypercalcemia	NN
cord-017142-vx3rgs4r	390	16	Evaluation	Evaluation	NNP
cord-017142-vx3rgs4r	390	17	and	and	CC
cord-017142-vx3rgs4r	390	18	management	management	NN
cord-017142-vx3rgs4r	390	19	of	of	IN
cord-017142-vx3rgs4r	390	20	the	the	DT
cord-017142-vx3rgs4r	390	21	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	390	22	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	391	1	Lenalidomide	Lenalidomide	NNP
cord-017142-vx3rgs4r	391	2	induced	induce	VBD
cord-017142-vx3rgs4r	391	3	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	391	4	lung	lung	NN
cord-017142-vx3rgs4r	391	5	disease	disease	NN
cord-017142-vx3rgs4r	391	6	.	.	.
cord-017142-vx3rgs4r	392	1	Drug	drug	NN
cord-017142-vx3rgs4r	392	2	induced	induce	VBN
cord-017142-vx3rgs4r	392	3	lung	lung	NN
cord-017142-vx3rgs4r	392	4	disease	disease	NN
cord-017142-vx3rgs4r	393	1	:	:	:
cord-017142-vx3rgs4r	393	2	case	case	NN
cord-017142-vx3rgs4r	393	3	reports	report	NNS
cord-017142-vx3rgs4r	393	4	Changing	change	VBG
cord-017142-vx3rgs4r	393	5	patterns	pattern	NNS
cord-017142-vx3rgs4r	393	6	of	of	IN
cord-017142-vx3rgs4r	393	7	infections	infection	NNS
cord-017142-vx3rgs4r	393	8	in	in	IN
cord-017142-vx3rgs4r	393	9	patients	patient	NNS
cord-017142-vx3rgs4r	393	10	with	with	IN
cord-017142-vx3rgs4r	393	11	multiple	multiple	JJ
cord-017142-vx3rgs4r	393	12	myeloma	myeloma	NN
cord-017142-vx3rgs4r	393	13	Autoimmune	autoimmune	JJ
cord-017142-vx3rgs4r	393	14	manifestations	manifestation	NNS
cord-017142-vx3rgs4r	393	15	in	in	IN
cord-017142-vx3rgs4r	393	16	patients	patient	NNS
cord-017142-vx3rgs4r	393	17	with	with	IN
cord-017142-vx3rgs4r	393	18	multiple	multiple	JJ
cord-017142-vx3rgs4r	393	19	myeloma	myeloma	NN
cord-017142-vx3rgs4r	393	20	and	and	CC
cord-017142-vx3rgs4r	393	21	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	393	22	gammopathy	gammopathy	NN
cord-017142-vx3rgs4r	393	23	of	of	IN
cord-017142-vx3rgs4r	393	24	undetermined	undetermined	JJ
cord-017142-vx3rgs4r	393	25	significance	significance	NN
cord-017142-vx3rgs4r	393	26	Serum	serum	NN
cord-017142-vx3rgs4r	393	27	free	free	JJ
cord-017142-vx3rgs4r	393	28	light	light	JJ
cord-017142-vx3rgs4r	393	29	chain	chain	NN
cord-017142-vx3rgs4r	393	30	analysis	analysis	NN
cord-017142-vx3rgs4r	393	31	for	for	IN
cord-017142-vx3rgs4r	393	32	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	393	33	,	,	,
cord-017142-vx3rgs4r	393	34	monitoring	monitoring	NN
cord-017142-vx3rgs4r	393	35	,	,	,
cord-017142-vx3rgs4r	393	36	and	and	CC
cord-017142-vx3rgs4r	393	37	prognosis	prognosis	NN
cord-017142-vx3rgs4r	393	38	of	of	IN
cord-017142-vx3rgs4r	393	39	monoclonal	monoclonal	JJ
cord-017142-vx3rgs4r	393	40	gammopathies	gammopathy	NNS
cord-017142-vx3rgs4r	394	1	Leptomeningeal	Leptomeningeal	NNP
cord-017142-vx3rgs4r	394	2	myeloma	myeloma	NN
cord-017142-vx3rgs4r	395	1	Pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	395	2	complications	complication	NNS
cord-017142-vx3rgs4r	395	3	of	of	IN
cord-017142-vx3rgs4r	395	4	bone	bone	NN
cord-017142-vx3rgs4r	395	5	marrow	marrow	NN
cord-017142-vx3rgs4r	395	6	transplantation	transplantation	NN
cord-017142-vx3rgs4r	395	7	Evidence	evidence	NN
cord-017142-vx3rgs4r	395	8	-	-	HYPH
cord-017142-vx3rgs4r	395	9	based	base	VBN
cord-017142-vx3rgs4r	395	10	focused	focused	JJ
cord-017142-vx3rgs4r	395	11	review	review	NN
cord-017142-vx3rgs4r	395	12	of	of	IN
cord-017142-vx3rgs4r	395	13	management	management	NN
cord-017142-vx3rgs4r	395	14	of	of	IN
cord-017142-vx3rgs4r	395	15	hyperviscosity	hyperviscosity	NNP
cord-017142-vx3rgs4r	395	16	syndrome	syndrome	NN
cord-017142-vx3rgs4r	395	17	Early	early	JJ
cord-017142-vx3rgs4r	395	18	-	-	HYPH
cord-017142-vx3rgs4r	395	19	onset	onset	NN
cord-017142-vx3rgs4r	395	20	severe	severe	JJ
cord-017142-vx3rgs4r	395	21	diffuse	diffuse	JJ
cord-017142-vx3rgs4r	395	22	alveolar	alveolar	NN
cord-017142-vx3rgs4r	395	23	hemorrhage	hemorrhage	NN
cord-017142-vx3rgs4r	395	24	after	after	IN
cord-017142-vx3rgs4r	395	25	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	395	26	administration	administration	NN
cord-017142-vx3rgs4r	395	27	suggestive	suggestive	JJ
cord-017142-vx3rgs4r	395	28	of	of	IN
cord-017142-vx3rgs4r	395	29	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	395	30	involvement	involvement	NN
cord-017142-vx3rgs4r	395	31	of	of	IN
cord-017142-vx3rgs4r	395	32	myeloma	myeloma	NN
cord-017142-vx3rgs4r	395	33	cells	cell	NNS
cord-017142-vx3rgs4r	396	1	Carfilzomib	Carfilzomib	NNP
cord-017142-vx3rgs4r	396	2	associated	associate	VBD
cord-017142-vx3rgs4r	396	3	thrombotic	thrombotic	JJ
cord-017142-vx3rgs4r	396	4	microangiopathy	microangiopathy	NN
cord-017142-vx3rgs4r	396	5	initially	initially	RB
cord-017142-vx3rgs4r	396	6	treated	treat	VBN
cord-017142-vx3rgs4r	396	7	with	with	IN
cord-017142-vx3rgs4r	396	8	therapeutic	therapeutic	JJ
cord-017142-vx3rgs4r	396	9	plasma	plasma	NN
cord-017142-vx3rgs4r	396	10	exchange	exchange	NN
cord-017142-vx3rgs4r	396	11	Invasive	invasive	JJ
cord-017142-vx3rgs4r	396	12	fungal	fungal	JJ
cord-017142-vx3rgs4r	396	13	infections	infection	NNS
cord-017142-vx3rgs4r	396	14	in	in	IN
cord-017142-vx3rgs4r	396	15	patients	patient	NNS
cord-017142-vx3rgs4r	396	16	with	with	IN
cord-017142-vx3rgs4r	396	17	multiple	multiple	JJ
cord-017142-vx3rgs4r	396	18	myeloma	myeloma	NN
cord-017142-vx3rgs4r	396	19	:	:	:
cord-017142-vx3rgs4r	396	20	a	a	DT
cord-017142-vx3rgs4r	396	21	multi	multi	JJ
cord-017142-vx3rgs4r	396	22	-	-	JJ
cord-017142-vx3rgs4r	396	23	center	center	JJ
cord-017142-vx3rgs4r	396	24	study	study	NN
cord-017142-vx3rgs4r	396	25	in	in	IN
cord-017142-vx3rgs4r	396	26	the	the	DT
cord-017142-vx3rgs4r	396	27	era	era	NN
cord-017142-vx3rgs4r	396	28	of	of	IN
cord-017142-vx3rgs4r	396	29	novel	novel	JJ
cord-017142-vx3rgs4r	396	30	myeloma	myeloma	NN
cord-017142-vx3rgs4r	396	31	therapies	therapy	NNS
cord-017142-vx3rgs4r	396	32	Hypersensitivity	Hypersensitivity	NNP
cord-017142-vx3rgs4r	396	33	pneumonitis	pneumonitis	NN
cord-017142-vx3rgs4r	396	34	-	-	HYPH
cord-017142-vx3rgs4r	396	35	like	like	JJ
cord-017142-vx3rgs4r	396	36	syndrome	syndrome	NN
cord-017142-vx3rgs4r	396	37	associated	associate	VBN
cord-017142-vx3rgs4r	396	38	with	with	IN
cord-017142-vx3rgs4r	396	39	the	the	DT
cord-017142-vx3rgs4r	396	40	use	use	NN
cord-017142-vx3rgs4r	396	41	of	of	IN
cord-017142-vx3rgs4r	396	42	lenalidomide	lenalidomide	JJ
cord-017142-vx3rgs4r	396	43	Spinal	spinal	JJ
cord-017142-vx3rgs4r	396	44	cord	cord	NN
cord-017142-vx3rgs4r	396	45	compression	compression	NN
cord-017142-vx3rgs4r	396	46	from	from	IN
cord-017142-vx3rgs4r	396	47	epidural	epidural	NN
cord-017142-vx3rgs4r	396	48	metastases	metastasis	NNS
cord-017142-vx3rgs4r	396	49	Incidence	incidence	NN
cord-017142-vx3rgs4r	396	50	and	and	CC
cord-017142-vx3rgs4r	396	51	outcome	outcome	NN
cord-017142-vx3rgs4r	396	52	of	of	IN
cord-017142-vx3rgs4r	396	53	patients	patient	NNS
cord-017142-vx3rgs4r	396	54	starting	start	VBG
cord-017142-vx3rgs4r	396	55	renal	renal	JJ
cord-017142-vx3rgs4r	396	56	replacement	replacement	NN
cord-017142-vx3rgs4r	396	57	therapy	therapy	NN
cord-017142-vx3rgs4r	396	58	for	for	IN
cord-017142-vx3rgs4r	396	59	end	end	NN
cord-017142-vx3rgs4r	396	60	-	-	HYPH
cord-017142-vx3rgs4r	396	61	stage	stage	NN
cord-017142-vx3rgs4r	396	62	renal	renal	JJ
cord-017142-vx3rgs4r	396	63	disease	disease	NN
cord-017142-vx3rgs4r	396	64	due	due	IN
cord-017142-vx3rgs4r	396	65	to	to	IN
cord-017142-vx3rgs4r	396	66	multiple	multiple	JJ
cord-017142-vx3rgs4r	396	67	myeloma	myeloma	NN
cord-017142-vx3rgs4r	396	68	or	or	CC
cord-017142-vx3rgs4r	396	69	light	light	JJ
cord-017142-vx3rgs4r	396	70	-	-	HYPH
cord-017142-vx3rgs4r	396	71	chain	chain	NN
cord-017142-vx3rgs4r	396	72	deposit	deposit	NN
cord-017142-vx3rgs4r	396	73	disease	disease	NN
cord-017142-vx3rgs4r	396	74	:	:	:
cord-017142-vx3rgs4r	397	1	an	an	DT
cord-017142-vx3rgs4r	397	2	ERA	ERA	NNP
cord-017142-vx3rgs4r	397	3	-	-	HYPH
cord-017142-vx3rgs4r	397	4	EDTA	EDTA	NNP
cord-017142-vx3rgs4r	397	5	Registry	Registry	NNP
cord-017142-vx3rgs4r	397	6	study	study	NN
cord-017142-vx3rgs4r	397	7	MR	MR	NNP
cord-017142-vx3rgs4r	397	8	findings	finding	NNS
cord-017142-vx3rgs4r	397	9	in	in	IN
cord-017142-vx3rgs4r	397	10	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	397	11	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	398	1	Implantable	implantable	JJ
cord-017142-vx3rgs4r	398	2	cardioverterdefibrillator	cardioverterdefibrillator	NN
cord-017142-vx3rgs4r	398	3	placement	placement	NN
cord-017142-vx3rgs4r	398	4	in	in	IN
cord-017142-vx3rgs4r	398	5	patients	patient	NNS
cord-017142-vx3rgs4r	398	6	with	with	IN
cord-017142-vx3rgs4r	398	7	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	398	8	amyloidosis	amyloidosis	NN
cord-017142-vx3rgs4r	398	9	Severe	severe	JJ
cord-017142-vx3rgs4r	398	10	reversible	reversible	JJ
cord-017142-vx3rgs4r	398	11	cardiac	cardiac	JJ
cord-017142-vx3rgs4r	398	12	failure	failure	NN
cord-017142-vx3rgs4r	398	13	after	after	IN
cord-017142-vx3rgs4r	398	14	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	398	15	treatment	treatment	NN
cord-017142-vx3rgs4r	398	16	combined	combine	VBN
cord-017142-vx3rgs4r	398	17	with	with	IN
cord-017142-vx3rgs4r	398	18	chemotherapy	chemotherapy	NN
cord-017142-vx3rgs4r	398	19	in	in	IN
cord-017142-vx3rgs4r	398	20	a	a	DT
cord-017142-vx3rgs4r	398	21	non	non	JJ
cord-017142-vx3rgs4r	398	22	-	-	JJ
cord-017142-vx3rgs4r	398	23	small	small	JJ
cord-017142-vx3rgs4r	398	24	cell	cell	NN
cord-017142-vx3rgs4r	398	25	lung	lung	NN
cord-017142-vx3rgs4r	398	26	cancer	cancer	NN
cord-017142-vx3rgs4r	398	27	patient	patient	NN
cord-017142-vx3rgs4r	398	28	:	:	:
cord-017142-vx3rgs4r	398	29	a	a	DT
cord-017142-vx3rgs4r	398	30	case	case	NN
cord-017142-vx3rgs4r	398	31	report	report	NN
cord-017142-vx3rgs4r	398	32	Regulation	regulation	NN
cord-017142-vx3rgs4r	398	33	of	of	IN
cord-017142-vx3rgs4r	398	34	calcitonin	calcitonin	NN
cord-017142-vx3rgs4r	398	35	receptor	receptor	NN
cord-017142-vx3rgs4r	398	36	by	by	IN
cord-017142-vx3rgs4r	398	37	glucocorticoid	glucocorticoid	NN
cord-017142-vx3rgs4r	398	38	in	in	IN
cord-017142-vx3rgs4r	398	39	human	human	JJ
cord-017142-vx3rgs4r	398	40	osteoclast	osteoclast	NN
cord-017142-vx3rgs4r	398	41	-	-	HYPH
cord-017142-vx3rgs4r	398	42	like	like	JJ
cord-017142-vx3rgs4r	398	43	cells	cell	NNS
cord-017142-vx3rgs4r	398	44	prepared	prepare	VBN
cord-017142-vx3rgs4r	398	45	in	in	IN
cord-017142-vx3rgs4r	398	46	vitro	vitro	FW
cord-017142-vx3rgs4r	398	47	using	use	VBG
cord-017142-vx3rgs4r	398	48	receptor	receptor	NN
cord-017142-vx3rgs4r	398	49	activator	activator	NN
cord-017142-vx3rgs4r	398	50	of	of	IN
cord-017142-vx3rgs4r	398	51	nuclear	nuclear	JJ
cord-017142-vx3rgs4r	398	52	factor	factor	NN
cord-017142-vx3rgs4r	398	53	-	-	HYPH
cord-017142-vx3rgs4r	398	54	κB	κb	CD
cord-017142-vx3rgs4r	398	55	ligand	ligand	NN
cord-017142-vx3rgs4r	398	56	and	and	CC
cord-017142-vx3rgs4r	398	57	macrophage	macrophage	NN
cord-017142-vx3rgs4r	398	58	colonystimulating	colonystimulating	NN
cord-017142-vx3rgs4r	398	59	factor	factor	NN
cord-017142-vx3rgs4r	398	60	Local	local	JJ
cord-017142-vx3rgs4r	398	61	control	control	NN
cord-017142-vx3rgs4r	398	62	and	and	CC
cord-017142-vx3rgs4r	398	63	survival	survival	NN
cord-017142-vx3rgs4r	398	64	in	in	IN
cord-017142-vx3rgs4r	398	65	spinal	spinal	JJ
cord-017142-vx3rgs4r	398	66	cord	cord	NN
cord-017142-vx3rgs4r	398	67	compression	compression	NN
cord-017142-vx3rgs4r	398	68	from	from	IN
cord-017142-vx3rgs4r	398	69	lymphoma	lymphoma	NN
cord-017142-vx3rgs4r	398	70	and	and	CC
cord-017142-vx3rgs4r	398	71	myeloma	myeloma	NN
cord-017142-vx3rgs4r	398	72	Management	Management	NNP
cord-017142-vx3rgs4r	398	73	of	of	IN
cord-017142-vx3rgs4r	398	74	tumor	tumor	NN
cord-017142-vx3rgs4r	398	75	lysis	lysis	NN
cord-017142-vx3rgs4r	398	76	syndrome	syndrome	NN
cord-017142-vx3rgs4r	398	77	in	in	IN
cord-017142-vx3rgs4r	398	78	patients	patient	NNS
cord-017142-vx3rgs4r	398	79	with	with	IN
cord-017142-vx3rgs4r	398	80	multiple	multiple	JJ
cord-017142-vx3rgs4r	398	81	myeloma	myeloma	NN
cord-017142-vx3rgs4r	398	82	during	during	IN
cord-017142-vx3rgs4r	398	83	bortezomib	bortezomib	JJ
cord-017142-vx3rgs4r	398	84	treatment	treatment	NN
cord-017142-vx3rgs4r	398	85	Thalidomidedexamethasone	Thalidomidedexamethasone	NNP
cord-017142-vx3rgs4r	398	86	as	as	IN
cord-017142-vx3rgs4r	398	87	primary	primary	JJ
cord-017142-vx3rgs4r	398	88	therapy	therapy	NN
cord-017142-vx3rgs4r	398	89	for	for	IN
cord-017142-vx3rgs4r	398	90	advanced	advanced	JJ
cord-017142-vx3rgs4r	398	91	multiple	multiple	JJ
cord-017142-vx3rgs4r	398	92	myeloma	myeloma	NN
cord-017142-vx3rgs4r	398	93	Carfilzomib	Carfilzomib	NNP
cord-017142-vx3rgs4r	398	94	-	-	HYPH
cord-017142-vx3rgs4r	398	95	associated	associate	VBN
cord-017142-vx3rgs4r	398	96	cardiovascular	cardiovascular	JJ
cord-017142-vx3rgs4r	398	97	adverse	adverse	JJ
cord-017142-vx3rgs4r	398	98	events	event	NNS
cord-017142-vx3rgs4r	398	99	:	:	:
cord-017142-vx3rgs4r	398	100	a	a	DT
cord-017142-vx3rgs4r	398	101	systematic	systematic	JJ
cord-017142-vx3rgs4r	398	102	review	review	NN
cord-017142-vx3rgs4r	398	103	and	and	CC
cord-017142-vx3rgs4r	398	104	meta	meta	NNP
cord-017142-vx3rgs4r	398	105	-	-	HYPH
cord-017142-vx3rgs4r	398	106	analysis	analysis	NN
cord-017142-vx3rgs4r	398	107	Multiple	multiple	JJ
cord-017142-vx3rgs4r	398	108	myeloma	myeloma	NN
cord-017142-vx3rgs4r	398	109	presenting	present	VBG
cord-017142-vx3rgs4r	398	110	as	as	IN
cord-017142-vx3rgs4r	398	111	interstitial	interstitial	JJ
cord-017142-vx3rgs4r	398	112	lung	lung	NN
cord-017142-vx3rgs4r	398	113	disease	disease	NN
cord-017142-vx3rgs4r	398	114	Into	into	IN
cord-017142-vx3rgs4r	398	115	the	the	DT
cord-017142-vx3rgs4r	398	116	heart	heart	NN
cord-017142-vx3rgs4r	398	117	:	:	:
cord-017142-vx3rgs4r	398	118	the	the	DT
cord-017142-vx3rgs4r	398	119	emerging	emerge	VBG
cord-017142-vx3rgs4r	398	120	role	role	NN
cord-017142-vx3rgs4r	398	121	of	of	IN
cord-017142-vx3rgs4r	398	122	the	the	DT
cord-017142-vx3rgs4r	398	123	ubiquitin	ubiquitin	NN
cord-017142-vx3rgs4r	398	124	-	-	HYPH
cord-017142-vx3rgs4r	398	125	proteasome	proteasome	VBN
cord-017142-vx3rgs4r	398	126	system	system	NN
cord-017142-vx3rgs4r	398	127	Incidence	incidence	NN
cord-017142-vx3rgs4r	398	128	and	and	CC
cord-017142-vx3rgs4r	398	129	risk	risk	NN
cord-017142-vx3rgs4r	398	130	of	of	IN
cord-017142-vx3rgs4r	398	131	cardiotoxicity	cardiotoxicity	NN
cord-017142-vx3rgs4r	398	132	associated	associate	VBN
cord-017142-vx3rgs4r	398	133	with	with	IN
cord-017142-vx3rgs4r	398	134	bortezomib	bortezomib	NNP
cord-017142-vx3rgs4r	398	135	in	in	IN
cord-017142-vx3rgs4r	398	136	the	the	DT
cord-017142-vx3rgs4r	398	137	treatment	treatment	NN
cord-017142-vx3rgs4r	398	138	of	of	IN
cord-017142-vx3rgs4r	398	139	cancer	cancer	NN
cord-017142-vx3rgs4r	398	140	:	:	:
cord-017142-vx3rgs4r	398	141	a	a	DT
cord-017142-vx3rgs4r	398	142	systematic	systematic	JJ
cord-017142-vx3rgs4r	398	143	review	review	NN
cord-017142-vx3rgs4r	398	144	and	and	CC
cord-017142-vx3rgs4r	398	145	metaanalysis	metaanalysis	NN
cord-017142-vx3rgs4r	398	146	Acute	acute	JJ
cord-017142-vx3rgs4r	398	147	spinal	spinal	JJ
cord-017142-vx3rgs4r	398	148	cord	cord	NN
cord-017142-vx3rgs4r	398	149	dysfunction	dysfunction	NN
cord-017142-vx3rgs4r	398	150	.	.	.
cord-017142-vx3rgs4r	399	1	In	in	IN
cord-017142-vx3rgs4r	399	2	:	:	:
cord-017142-vx3rgs4r	399	3	The	the	DT
cord-017142-vx3rgs4r	399	4	Washington	Washington	NNP
cord-017142-vx3rgs4r	399	5	manual	manual	NN
cord-017142-vx3rgs4r	399	6	of	of	IN
cord-017142-vx3rgs4r	399	7	medical	medical	JJ
cord-017142-vx3rgs4r	399	8	therapeutics	therapeutic	NNS
cord-017142-vx3rgs4r	399	9	Retracted	retract	VBD
cord-017142-vx3rgs4r	399	10	:	:	:
cord-017142-vx3rgs4r	399	11	overview	overview	NN
cord-017142-vx3rgs4r	399	12	of	of	IN
cord-017142-vx3rgs4r	399	13	recent	recent	JJ
cord-017142-vx3rgs4r	399	14	trends	trend	NNS
cord-017142-vx3rgs4r	399	15	in	in	IN
cord-017142-vx3rgs4r	399	16	diagnosis	diagnosis	NN
cord-017142-vx3rgs4r	399	17	and	and	CC
cord-017142-vx3rgs4r	399	18	management	management	NN
cord-017142-vx3rgs4r	399	19	of	of	IN
cord-017142-vx3rgs4r	399	20	leptomeningeal	leptomeningeal	JJ
cord-017142-vx3rgs4r	399	21	multiple	multiple	JJ
cord-017142-vx3rgs4r	399	22	myeloma	myeloma	NN
cord-017142-vx3rgs4r	399	23	Multiple	multiple	JJ
cord-017142-vx3rgs4r	399	24	myeloma	myeloma	NN
cord-017142-vx3rgs4r	399	25	involving	involve	VBG
cord-017142-vx3rgs4r	399	26	skin	skin	NN
cord-017142-vx3rgs4r	399	27	and	and	CC
cord-017142-vx3rgs4r	399	28	pulmonary	pulmonary	JJ
cord-017142-vx3rgs4r	399	29	parenchyma	parenchyma	NN
cord-017142-vx3rgs4r	399	30	after	after	IN
cord-017142-vx3rgs4r	399	31	autologous	autologous	JJ
cord-017142-vx3rgs4r	399	32	stem	stem	NN
cord-017142-vx3rgs4r	399	33	cell	cell	NN
cord-017142-vx3rgs4r	399	34	transplantation	transplantation	NN
cord-017142-vx3rgs4r	399	35	Proteasome	Proteasome	NNP
cord-017142-vx3rgs4r	399	36	inhibitor	inhibitor	NN
cord-017142-vx3rgs4r	399	37	associated	associate	VBD
cord-017142-vx3rgs4r	399	38	thrombotic	thrombotic	JJ
cord-017142-vx3rgs4r	399	39	microangiopathy	microangiopathy	NNP
cord-017142-vx3rgs4r	399	40	Hypercalcemia	Hypercalcemia	NNP
cord-017142-vx3rgs4r	399	41	remains	remain	VBZ
cord-017142-vx3rgs4r	399	42	an	an	DT
cord-017142-vx3rgs4r	399	43	adverse	adverse	JJ
cord-017142-vx3rgs4r	399	44	prognostic	prognostic	JJ
cord-017142-vx3rgs4r	399	45	factor	factor	NN
cord-017142-vx3rgs4r	399	46	for	for	IN
cord-017142-vx3rgs4r	399	47	newly	newly	RB
cord-017142-vx3rgs4r	399	48	diagnosed	diagnose	VBN
cord-017142-vx3rgs4r	399	49	multiple	multiple	JJ
cord-017142-vx3rgs4r	399	50	myeloma	myeloma	NN
cord-017142-vx3rgs4r	399	51	patients	patient	NNS
cord-017142-vx3rgs4r	399	52	in	in	IN
cord-017142-vx3rgs4r	399	53	the	the	DT
cord-017142-vx3rgs4r	399	54	era	era	NN
cord-017142-vx3rgs4r	399	55	of	of	IN
cord-017142-vx3rgs4r	399	56	novel	novel	JJ
cord-017142-vx3rgs4r	399	57	antimyeloma	antimyeloma	NNP
cord-017142-vx3rgs4r	399	58	therapies	therapy	NNS
cord-017142-vx3rgs4r	399	59	Conflicts	conflict	NNS
cord-017142-vx3rgs4r	399	60	of	of	IN
cord-017142-vx3rgs4r	399	61	Interest	Interest	NNP
cord-017142-vx3rgs4r	399	62	KP	KP	NNP
cord-017142-vx3rgs4r	399	63	=	=	SYM
cord-017142-vx3rgs4r	399	64	research	research	NN
cord-017142-vx3rgs4r	399	65	funds	fund	NNS
cord-017142-vx3rgs4r	399	66	from	from	IN
cord-017142-vx3rgs4r	399	67	Poseida	Poseida	NNP
cord-017142-vx3rgs4r	399	68	,	,	,
cord-017142-vx3rgs4r	399	69	Intrexon	Intrexon	NNP
cord-017142-vx3rgs4r	399	70	/	/	SYM
cord-017142-vx3rgs4r	399	71	Ziopharm	Ziopharm	NNP
cord-017142-vx3rgs4r	399	72	,	,	,
cord-017142-vx3rgs4r	399	73	Takeda	Takeda	NNP
cord-017142-vx3rgs4r	399	74	.	.	.
cord-017142-vx3rgs4r	400	1	Advisory	Advisory	NNP
cord-017142-vx3rgs4r	400	2	board	board	NN
cord-017142-vx3rgs4r	400	3	/	/	SYM
cord-017142-vx3rgs4r	400	4	consultancy	consultancy	NN
cord-017142-vx3rgs4r	400	5	in	in	IN
cord-017142-vx3rgs4r	400	6	Takeda	Takeda	NNP
cord-017142-vx3rgs4r	400	7	,	,	,
cord-017142-vx3rgs4r	400	8	DAVA	DAVA	NNP
cord-017142-vx3rgs4r	400	9	oncology	oncology	NN
cord-017142-vx3rgs4r	400	10	,	,	,
cord-017142-vx3rgs4r	400	11	Celgene	Celgene	NNP
cord-017142-vx3rgs4r	400	12	,	,	,
cord-017142-vx3rgs4r	400	13	Janssen	Janssen	NNP
cord-017142-vx3rgs4r	400	14	,	,	,
cord-017142-vx3rgs4r	400	15	Amgen	Amgen	NNP
cord-017142-vx3rgs4r	400	16	,	,	,
cord-017142-vx3rgs4r	400	17	BMS	BMS	NNP
cord-017142-vx3rgs4r	400	18	,	,	,
cord-017142-vx3rgs4r	400	19	and	and	CC
cord-017142-vx3rgs4r	400	20	Oncopeptides	Oncopeptides	NNP
cord-017142-vx3rgs4r	400	21	.	.	.