id	sid	tid	token	lemma	pos
cord-267965-84sotgds	1	1	key	key	JJ
cord-267965-84sotgds	1	2	:	:	:
cord-267965-84sotgds	1	3	cord-267965	cord-267965	NNP
cord-267965-84sotgds	1	4	-	-	HYPH
cord-267965-84sotgds	1	5	84sotgds	84sotgds	CD
cord-267965-84sotgds	1	6	authors	author	NNS
cord-267965-84sotgds	1	7	:	:	:
cord-267965-84sotgds	1	8	Noll	Noll	NNP
cord-267965-84sotgds	1	9	,	,	,
cord-267965-84sotgds	1	10	Kelsey	Kelsey	NNP
cord-267965-84sotgds	1	11	E.	E.	NNP
cord-267965-84sotgds	1	12	;	;	:
cord-267965-84sotgds	1	13	Ferris	Ferris	NNP
cord-267965-84sotgds	1	14	,	,	,
cord-267965-84sotgds	1	15	Martin	Martin	NNP
cord-267965-84sotgds	1	16	T.	T.	NNP
cord-267965-84sotgds	1	17	;	;	:
cord-267965-84sotgds	1	18	Heise	Heise	NNP
cord-267965-84sotgds	1	19	,	,	,
cord-267965-84sotgds	2	1	Mark	Mark	NNP
cord-267965-84sotgds	2	2	T.	T.	NNP
cord-267965-84sotgds	2	3	title	title	NN
cord-267965-84sotgds	2	4	:	:	:
cord-267965-84sotgds	3	1	The	the	DT
cord-267965-84sotgds	3	2	Collaborative	Collaborative	NNP
cord-267965-84sotgds	3	3	Cross	Cross	NNP
cord-267965-84sotgds	3	4	:	:	:
cord-267965-84sotgds	3	5	A	A	NNP
cord-267965-84sotgds	3	6	Systems	Systems	NNP
cord-267965-84sotgds	3	7	Genetics	Genetics	NNP
cord-267965-84sotgds	3	8	Resource	Resource	NNP
cord-267965-84sotgds	3	9	for	for	IN
cord-267965-84sotgds	3	10	Studying	study	VBG
cord-267965-84sotgds	3	11	Host	Host	NNP
cord-267965-84sotgds	3	12	-	-	HYPH
cord-267965-84sotgds	3	13	Pathogen	Pathogen	NNP
cord-267965-84sotgds	3	14	Interactions	Interactions	NNPS
cord-267965-84sotgds	3	15	date	date	NN
cord-267965-84sotgds	3	16	:	:	:
cord-267965-84sotgds	3	17	2019	2019	CD
cord-267965-84sotgds	3	18	-	-	HYPH
cord-267965-84sotgds	3	19	04	04	CD
cord-267965-84sotgds	3	20	-	-	SYM
cord-267965-84sotgds	3	21	10	10	CD
cord-267965-84sotgds	3	22	journal	journal	NN
cord-267965-84sotgds	3	23	:	:	:
cord-267965-84sotgds	4	1	Cell	Cell	NNP
cord-267965-84sotgds	4	2	Host	Host	NNP
cord-267965-84sotgds	4	3	&	&	CC
cord-267965-84sotgds	4	4	Microbe	Microbe	NNP
cord-267965-84sotgds	4	5	DOI	DOI	NNP
cord-267965-84sotgds	4	6	:	:	:
cord-267965-84sotgds	4	7	10.1016/	10.1016/	CD
cord-267965-84sotgds	5	1	j.chom.2019.03.009	j.chom.2019.03.009	NNP
cord-267965-84sotgds	5	2	sha	sha	NNP
cord-267965-84sotgds	5	3	:	:	:
cord-267965-84sotgds	5	4	bde262723f5c569321a2367d69815cc56ad00904	bde262723f5c569321a2367d69815cc56ad00904	NNP
cord-267965-84sotgds	5	5	doc_id	doc_id	CD
cord-267965-84sotgds	5	6	:	:	:
cord-267965-84sotgds	5	7	267965	267965	CD
cord-267965-84sotgds	5	8	cord_uid	cord_uid	NNS
cord-267965-84sotgds	5	9	:	:	:
cord-267965-84sotgds	6	1	84sotgds	84sotgds	CD
cord-267965-84sotgds	7	1	Host	host	JJ
cord-267965-84sotgds	7	2	genetic	genetic	JJ
cord-267965-84sotgds	7	3	variation	variation	NN
cord-267965-84sotgds	7	4	has	have	VBZ
cord-267965-84sotgds	7	5	a	a	DT
cord-267965-84sotgds	7	6	major	major	JJ
cord-267965-84sotgds	7	7	impact	impact	NN
cord-267965-84sotgds	7	8	on	on	IN
cord-267965-84sotgds	7	9	infectious	infectious	JJ
cord-267965-84sotgds	7	10	disease	disease	NN
cord-267965-84sotgds	7	11	susceptibility	susceptibility	NN
cord-267965-84sotgds	7	12	.	.	.
cord-267965-84sotgds	8	1	The	the	DT
cord-267965-84sotgds	8	2	study	study	NN
cord-267965-84sotgds	8	3	of	of	IN
cord-267965-84sotgds	8	4	pathogen	pathogen	NN
cord-267965-84sotgds	8	5	resistance	resistance	NN
cord-267965-84sotgds	8	6	genes	gene	NNS
cord-267965-84sotgds	8	7	,	,	,
cord-267965-84sotgds	8	8	largely	largely	RB
cord-267965-84sotgds	8	9	aided	aid	VBN
cord-267965-84sotgds	8	10	by	by	IN
cord-267965-84sotgds	8	11	mouse	mouse	NN
cord-267965-84sotgds	8	12	models	model	NNS
cord-267965-84sotgds	8	13	,	,	,
cord-267965-84sotgds	8	14	has	have	VBZ
cord-267965-84sotgds	8	15	significantly	significantly	RB
cord-267965-84sotgds	8	16	advanced	advance	VBN
cord-267965-84sotgds	8	17	our	-PRON-	PRP$
cord-267965-84sotgds	8	18	understanding	understanding	NN
cord-267965-84sotgds	8	19	of	of	IN
cord-267965-84sotgds	8	20	infectious	infectious	JJ
cord-267965-84sotgds	8	21	disease	disease	NN
cord-267965-84sotgds	8	22	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	8	23	.	.	.
cord-267965-84sotgds	9	1	The	the	DT
cord-267965-84sotgds	9	2	Collaborative	Collaborative	NNP
cord-267965-84sotgds	9	3	Cross	Cross	NNP
cord-267965-84sotgds	9	4	(	(	-LRB-
cord-267965-84sotgds	9	5	CC	CC	NNP
cord-267965-84sotgds	9	6	)	)	-RRB-
cord-267965-84sotgds	9	7	,	,	,
cord-267965-84sotgds	9	8	a	a	DT
cord-267965-84sotgds	9	9	newly	newly	RB
cord-267965-84sotgds	9	10	developed	develop	VBN
cord-267965-84sotgds	9	11	multi	multi	JJ
cord-267965-84sotgds	9	12	-	-	JJ
cord-267965-84sotgds	9	13	parental	parental	JJ
cord-267965-84sotgds	9	14	mouse	mouse	NN
cord-267965-84sotgds	9	15	genetic	genetic	JJ
cord-267965-84sotgds	9	16	reference	reference	NN
cord-267965-84sotgds	9	17	population	population	NN
cord-267965-84sotgds	9	18	,	,	,
cord-267965-84sotgds	9	19	serves	serve	VBZ
cord-267965-84sotgds	9	20	as	as	IN
cord-267965-84sotgds	9	21	a	a	DT
cord-267965-84sotgds	9	22	tractable	tractable	JJ
cord-267965-84sotgds	9	23	model	model	NN
cord-267965-84sotgds	9	24	system	system	NN
cord-267965-84sotgds	9	25	to	to	TO
cord-267965-84sotgds	9	26	study	study	VB
cord-267965-84sotgds	9	27	how	how	WRB
cord-267965-84sotgds	9	28	pathogens	pathogen	NNS
cord-267965-84sotgds	9	29	interact	interact	VBP
cord-267965-84sotgds	9	30	with	with	IN
cord-267965-84sotgds	9	31	genetically	genetically	RB
cord-267965-84sotgds	9	32	diverse	diverse	JJ
cord-267965-84sotgds	9	33	populations	population	NNS
cord-267965-84sotgds	9	34	.	.	.
cord-267965-84sotgds	10	1	In	in	IN
cord-267965-84sotgds	10	2	this	this	DT
cord-267965-84sotgds	10	3	review	review	NN
cord-267965-84sotgds	10	4	,	,	,
cord-267965-84sotgds	10	5	we	-PRON-	PRP
cord-267965-84sotgds	10	6	summarize	summarize	VBP
cord-267965-84sotgds	10	7	progress	progress	NN
cord-267965-84sotgds	10	8	utilizing	utilize	VBG
cord-267965-84sotgds	10	9	the	the	DT
cord-267965-84sotgds	10	10	CC	CC	NNP
cord-267965-84sotgds	10	11	as	as	IN
cord-267965-84sotgds	10	12	a	a	DT
cord-267965-84sotgds	10	13	platform	platform	NN
cord-267965-84sotgds	10	14	to	to	TO
cord-267965-84sotgds	10	15	develop	develop	VB
cord-267965-84sotgds	10	16	improved	improved	JJ
cord-267965-84sotgds	10	17	models	model	NNS
cord-267965-84sotgds	10	18	of	of	IN
cord-267965-84sotgds	10	19	pathogen	pathogen	NN
cord-267965-84sotgds	10	20	-	-	HYPH
cord-267965-84sotgds	10	21	induced	induce	VBN
cord-267965-84sotgds	10	22	disease	disease	NN
cord-267965-84sotgds	10	23	and	and	CC
cord-267965-84sotgds	10	24	to	to	TO
cord-267965-84sotgds	10	25	map	map	VB
cord-267965-84sotgds	10	26	polymorphic	polymorphic	JJ
cord-267965-84sotgds	10	27	host	host	NN
cord-267965-84sotgds	10	28	response	response	NN
cord-267965-84sotgds	10	29	loci	locus	NNS
cord-267965-84sotgds	10	30	associated	associate	VBN
cord-267965-84sotgds	10	31	with	with	IN
cord-267965-84sotgds	10	32	variation	variation	NN
cord-267965-84sotgds	10	33	in	in	IN
cord-267965-84sotgds	10	34	susceptibility	susceptibility	NN
cord-267965-84sotgds	10	35	to	to	IN
cord-267965-84sotgds	10	36	pathogens	pathogen	NNS
cord-267965-84sotgds	10	37	.	.	.
cord-267965-84sotgds	11	1	Pathogens	pathogen	NNS
cord-267965-84sotgds	11	2	often	often	RB
cord-267965-84sotgds	11	3	cause	cause	VBP
cord-267965-84sotgds	11	4	variable	variable	JJ
cord-267965-84sotgds	11	5	disease	disease	NN
cord-267965-84sotgds	11	6	outcomes	outcome	NNS
cord-267965-84sotgds	11	7	across	across	IN
cord-267965-84sotgds	11	8	infected	infect	VBN
cord-267965-84sotgds	11	9	individuals	individual	NNS
cord-267965-84sotgds	11	10	,	,	,
cord-267965-84sotgds	11	11	ranging	range	VBG
cord-267965-84sotgds	11	12	from	from	IN
cord-267965-84sotgds	11	13	asymptomatic	asymptomatic	JJ
cord-267965-84sotgds	11	14	infection	infection	NN
cord-267965-84sotgds	11	15	to	to	IN
cord-267965-84sotgds	11	16	severe	severe	JJ
cord-267965-84sotgds	11	17	or	or	CC
cord-267965-84sotgds	11	18	fatal	fatal	JJ
cord-267965-84sotgds	11	19	disease	disease	NN
cord-267965-84sotgds	11	20	.	.	.
cord-267965-84sotgds	12	1	Multiple	multiple	JJ
cord-267965-84sotgds	12	2	factors	factor	NNS
cord-267965-84sotgds	12	3	influence	influence	VBP
cord-267965-84sotgds	12	4	an	an	DT
cord-267965-84sotgds	12	5	individual	individual	NN
cord-267965-84sotgds	12	6	's	's	POS
cord-267965-84sotgds	12	7	susceptibility	susceptibility	NN
cord-267965-84sotgds	12	8	to	to	IN
cord-267965-84sotgds	12	9	a	a	DT
cord-267965-84sotgds	12	10	pathogen	pathogen	NN
cord-267965-84sotgds	12	11	,	,	,
cord-267965-84sotgds	12	12	including	include	VBG
cord-267965-84sotgds	12	13	variation	variation	NN
cord-267965-84sotgds	12	14	in	in	IN
cord-267965-84sotgds	12	15	pathogen	pathogen	NN
cord-267965-84sotgds	12	16	dose	dose	NN
cord-267965-84sotgds	12	17	or	or	CC
cord-267965-84sotgds	12	18	virulence	virulence	NN
cord-267965-84sotgds	12	19	as	as	RB
cord-267965-84sotgds	12	20	well	well	RB
cord-267965-84sotgds	12	21	as	as	IN
cord-267965-84sotgds	12	22	host	host	NN
cord-267965-84sotgds	12	23	age	age	NN
cord-267965-84sotgds	12	24	,	,	,
cord-267965-84sotgds	12	25	prior	prior	JJ
cord-267965-84sotgds	12	26	immune	immune	JJ
cord-267965-84sotgds	12	27	experience	experience	NN
cord-267965-84sotgds	12	28	,	,	,
cord-267965-84sotgds	12	29	microbiome	microbiome	NN
cord-267965-84sotgds	12	30	/	/	SYM
cord-267965-84sotgds	12	31	coinfection	coinfection	NN
cord-267965-84sotgds	12	32	,	,	,
cord-267965-84sotgds	12	33	and	and	CC
cord-267965-84sotgds	12	34	genetics	genetic	NNS
cord-267965-84sotgds	12	35	.	.	.
cord-267965-84sotgds	13	1	A	a	DT
cord-267965-84sotgds	13	2	role	role	NN
cord-267965-84sotgds	13	3	for	for	IN
cord-267965-84sotgds	13	4	host	host	NN
cord-267965-84sotgds	13	5	genetics	genetic	NNS
cord-267965-84sotgds	13	6	in	in	IN
cord-267965-84sotgds	13	7	pathogen	pathogen	NN
cord-267965-84sotgds	13	8	susceptibility	susceptibility	NN
cord-267965-84sotgds	13	9	is	be	VBZ
cord-267965-84sotgds	13	10	supported	support	VBN
cord-267965-84sotgds	13	11	both	both	CC
cord-267965-84sotgds	13	12	by	by	IN
cord-267965-84sotgds	13	13	twin	twin	JJ
cord-267965-84sotgds	13	14	studies	study	NNS
cord-267965-84sotgds	13	15	(	(	-LRB-
cord-267965-84sotgds	13	16	Kallmann	Kallmann	NNP
cord-267965-84sotgds	13	17	and	and	CC
cord-267965-84sotgds	13	18	Reisner	Reisner	NNP
cord-267965-84sotgds	13	19	,	,	,
cord-267965-84sotgds	13	20	1943	1943	CD
cord-267965-84sotgds	13	21	)	)	-RRB-
cord-267965-84sotgds	13	22	and	and	CC
cord-267965-84sotgds	13	23	by	by	IN
cord-267965-84sotgds	13	24	evidence	evidence	NN
cord-267965-84sotgds	13	25	of	of	IN
cord-267965-84sotgds	13	26	pathogen	pathogen	NN
cord-267965-84sotgds	13	27	-	-	HYPH
cord-267965-84sotgds	13	28	driven	drive	VBN
cord-267965-84sotgds	13	29	selective	selective	JJ
cord-267965-84sotgds	13	30	pressure	pressure	NN
cord-267965-84sotgds	13	31	on	on	IN
cord-267965-84sotgds	13	32	the	the	DT
cord-267965-84sotgds	13	33	evolution	evolution	NN
cord-267965-84sotgds	13	34	of	of	IN
cord-267965-84sotgds	13	35	the	the	DT
cord-267965-84sotgds	13	36	human	human	JJ
cord-267965-84sotgds	13	37	immune	immune	NN
cord-267965-84sotgds	13	38	system	system	NN
cord-267965-84sotgds	13	39	(	(	-LRB-
cord-267965-84sotgds	13	40	Cagliani	Cagliani	NNP
cord-267965-84sotgds	13	41	and	and	CC
cord-267965-84sotgds	13	42	Sironi	Sironi	NNP
cord-267965-84sotgds	13	43	,	,	,
cord-267965-84sotgds	13	44	2013	2013	CD
cord-267965-84sotgds	13	45	)	)	-RRB-
cord-267965-84sotgds	13	46	.	.	.
cord-267965-84sotgds	14	1	Human	human	JJ
cord-267965-84sotgds	14	2	genetic	genetic	JJ
cord-267965-84sotgds	14	3	studies	study	NNS
cord-267965-84sotgds	14	4	have	have	VBP
cord-267965-84sotgds	14	5	demonstrated	demonstrate	VBN
cord-267965-84sotgds	14	6	a	a	DT
cord-267965-84sotgds	14	7	role	role	NN
cord-267965-84sotgds	14	8	for	for	IN
cord-267965-84sotgds	14	9	host	host	NN
cord-267965-84sotgds	14	10	genetics	genetic	NNS
cord-267965-84sotgds	14	11	in	in	IN
cord-267965-84sotgds	14	12	pathogen	pathogen	NN
cord-267965-84sotgds	14	13	susceptibility	susceptibility	NN
cord-267965-84sotgds	14	14	and	and	CC
cord-267965-84sotgds	14	15	identified	identify	VBD
cord-267965-84sotgds	14	16	polymorphic	polymorphic	JJ
cord-267965-84sotgds	14	17	genetic	genetic	JJ
cord-267965-84sotgds	14	18	loci	locus	NNS
cord-267965-84sotgds	14	19	and	and	CC
cord-267965-84sotgds	14	20	genes	gene	NNS
cord-267965-84sotgds	14	21	associated	associate	VBN
cord-267965-84sotgds	14	22	with	with	IN
cord-267965-84sotgds	14	23	variation	variation	NN
cord-267965-84sotgds	14	24	in	in	IN
cord-267965-84sotgds	14	25	susceptibility	susceptibility	NN
cord-267965-84sotgds	14	26	to	to	IN
cord-267965-84sotgds	14	27	specific	specific	JJ
cord-267965-84sotgds	14	28	pathogens	pathogen	NNS
cord-267965-84sotgds	14	29	(	(	-LRB-
cord-267965-84sotgds	14	30	e.g.	e.g.	RB
cord-267965-84sotgds	14	31	,	,	,
cord-267965-84sotgds	14	32	HIV	HIV	NNP
cord-267965-84sotgds	14	33	)	)	-RRB-
cord-267965-84sotgds	15	1	(	(	-LRB-
cord-267965-84sotgds	15	2	McLaren	McLaren	NNP
cord-267965-84sotgds	15	3	et	et	NNP
cord-267965-84sotgds	15	4	al	al	NNP
cord-267965-84sotgds	15	5	.	.	NNP
cord-267965-84sotgds	15	6	,	,	,
cord-267965-84sotgds	15	7	2015	2015	CD
cord-267965-84sotgds	15	8	)	)	-RRB-
cord-267965-84sotgds	15	9	,	,	,
cord-267965-84sotgds	15	10	classes	class	NNS
cord-267965-84sotgds	15	11	of	of	IN
cord-267965-84sotgds	15	12	pathogens	pathogen	NNS
cord-267965-84sotgds	15	13	(	(	-LRB-
cord-267965-84sotgds	15	14	e.g.	e.g.	RB
cord-267965-84sotgds	15	15	,	,	,
cord-267965-84sotgds	15	16	mycobacteria	mycobacterium	NNS
cord-267965-84sotgds	15	17	)	)	-RRB-
cord-267965-84sotgds	16	1	(	(	-LRB-
cord-267965-84sotgds	16	2	Bustamante	Bustamante	NNP
cord-267965-84sotgds	16	3	et	et	NNP
cord-267965-84sotgds	16	4	al	al	NNP
cord-267965-84sotgds	16	5	.	.	NNP
cord-267965-84sotgds	16	6	,	,	,
cord-267965-84sotgds	16	7	2014	2014	CD
cord-267965-84sotgds	16	8	)	)	-RRB-
cord-267965-84sotgds	16	9	,	,	,
cord-267965-84sotgds	16	10	and	and	CC
cord-267965-84sotgds	16	11	more	more	RBR
cord-267965-84sotgds	16	12	generalized	generalized	JJ
cord-267965-84sotgds	16	13	primary	primary	JJ
cord-267965-84sotgds	16	14	immunodeficiencies	immunodeficiency	NNS
cord-267965-84sotgds	16	15	(	(	-LRB-
cord-267965-84sotgds	16	16	PIDs	PIDs	NNP
cord-267965-84sotgds	16	17	)	)	-RRB-
cord-267965-84sotgds	16	18	that	that	WDT
cord-267965-84sotgds	16	19	result	result	VBP
cord-267965-84sotgds	16	20	in	in	IN
cord-267965-84sotgds	16	21	severe	severe	JJ
cord-267965-84sotgds	16	22	immune	immune	JJ
cord-267965-84sotgds	16	23	defects	defect	NNS
cord-267965-84sotgds	16	24	(	(	-LRB-
cord-267965-84sotgds	16	25	Chapman	Chapman	NNP
cord-267965-84sotgds	16	26	and	and	CC
cord-267965-84sotgds	16	27	Hill	Hill	NNP
cord-267965-84sotgds	16	28	,	,	,
cord-267965-84sotgds	16	29	2012	2012	CD
cord-267965-84sotgds	16	30	)	)	-RRB-
cord-267965-84sotgds	16	31	.	.	.
cord-267965-84sotgds	17	1	This	this	DT
cord-267965-84sotgds	17	2	information	information	NN
cord-267965-84sotgds	17	3	has	have	VBZ
cord-267965-84sotgds	17	4	enhanced	enhance	VBN
cord-267965-84sotgds	17	5	our	-PRON-	PRP$
cord-267965-84sotgds	17	6	understanding	understanding	NN
cord-267965-84sotgds	17	7	of	of	IN
cord-267965-84sotgds	17	8	how	how	WRB
cord-267965-84sotgds	17	9	host	host	JJ
cord-267965-84sotgds	17	10	genetic	genetic	JJ
cord-267965-84sotgds	17	11	variation	variation	NN
cord-267965-84sotgds	17	12	affects	affect	VBZ
cord-267965-84sotgds	17	13	pathogen	pathogen	NN
cord-267965-84sotgds	17	14	susceptibility	susceptibility	NN
cord-267965-84sotgds	17	15	and	and	CC
cord-267965-84sotgds	17	16	how	how	WRB
cord-267965-84sotgds	17	17	specific	specific	JJ
cord-267965-84sotgds	17	18	genes	gene	NNS
cord-267965-84sotgds	17	19	regulate	regulate	VBP
cord-267965-84sotgds	17	20	human	human	JJ
cord-267965-84sotgds	17	21	immunity	immunity	NN
cord-267965-84sotgds	17	22	and	and	CC
cord-267965-84sotgds	17	23	host	host	NN
cord-267965-84sotgds	17	24	-	-	HYPH
cord-267965-84sotgds	17	25	pathogen	pathogen	NN
cord-267965-84sotgds	17	26	interactions	interaction	NNS
cord-267965-84sotgds	17	27	.	.	.
cord-267965-84sotgds	18	1	While	while	IN
cord-267965-84sotgds	18	2	advances	advance	NNS
cord-267965-84sotgds	18	3	in	in	IN
cord-267965-84sotgds	18	4	human	human	JJ
cord-267965-84sotgds	18	5	genetic	genetic	JJ
cord-267965-84sotgds	18	6	analysis	analysis	NN
cord-267965-84sotgds	18	7	have	have	VBP
cord-267965-84sotgds	18	8	led	lead	VBN
cord-267965-84sotgds	18	9	to	to	IN
cord-267965-84sotgds	18	10	the	the	DT
cord-267965-84sotgds	18	11	identification	identification	NN
cord-267965-84sotgds	18	12	of	of	IN
cord-267965-84sotgds	18	13	several	several	JJ
cord-267965-84sotgds	18	14	host	host	NN
cord-267965-84sotgds	18	15	genes	gene	NNS
cord-267965-84sotgds	18	16	that	that	WDT
cord-267965-84sotgds	18	17	regulate	regulate	VBP
cord-267965-84sotgds	18	18	pathogen	pathogen	NN
cord-267965-84sotgds	18	19	susceptibility	susceptibility	NN
cord-267965-84sotgds	18	20	in	in	IN
cord-267965-84sotgds	18	21	humans	human	NNS
cord-267965-84sotgds	18	22	(	(	-LRB-
cord-267965-84sotgds	18	23	Newport	Newport	NNP
cord-267965-84sotgds	18	24	and	and	CC
cord-267965-84sotgds	18	25	Finan	Finan	NNP
cord-267965-84sotgds	18	26	,	,	,
cord-267965-84sotgds	18	27	2011	2011	CD
cord-267965-84sotgds	18	28	)	)	-RRB-
cord-267965-84sotgds	18	29	,	,	,
cord-267965-84sotgds	18	30	much	much	JJ
cord-267965-84sotgds	18	31	of	of	IN
cord-267965-84sotgds	18	32	our	-PRON-	PRP$
cord-267965-84sotgds	18	33	understanding	understanding	NN
cord-267965-84sotgds	18	34	of	of	IN
cord-267965-84sotgds	18	35	how	how	WRB
cord-267965-84sotgds	18	36	specific	specific	JJ
cord-267965-84sotgds	18	37	genes	gene	NNS
cord-267965-84sotgds	18	38	affect	affect	VBP
cord-267965-84sotgds	18	39	infectious	infectious	JJ
cord-267965-84sotgds	18	40	disease	disease	NN
cord-267965-84sotgds	18	41	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	18	42	in	in	IN
cord-267965-84sotgds	18	43	mammals	mammal	NNS
cord-267965-84sotgds	18	44	has	have	VBZ
cord-267965-84sotgds	18	45	come	come	VBN
cord-267965-84sotgds	18	46	from	from	IN
cord-267965-84sotgds	18	47	studies	study	NNS
cord-267965-84sotgds	18	48	using	use	VBG
cord-267965-84sotgds	18	49	mouse	mouse	NN
cord-267965-84sotgds	18	50	models	model	NNS
cord-267965-84sotgds	18	51	(	(	-LRB-
cord-267965-84sotgds	18	52	Masopust	Masopust	NNP
cord-267965-84sotgds	18	53	et	et	NNP
cord-267965-84sotgds	18	54	al	al	NNP
cord-267965-84sotgds	18	55	.	.	NNP
cord-267965-84sotgds	18	56	,	,	,
cord-267965-84sotgds	18	57	2017	2017	CD
cord-267965-84sotgds	18	58	)	)	-RRB-
cord-267965-84sotgds	18	59	.	.	.
cord-267965-84sotgds	19	1	This	this	DT
cord-267965-84sotgds	19	2	is	be	VBZ
cord-267965-84sotgds	19	3	in	in	IN
cord-267965-84sotgds	19	4	large	large	JJ
cord-267965-84sotgds	19	5	part	part	NN
cord-267965-84sotgds	19	6	due	due	IN
cord-267965-84sotgds	19	7	to	to	IN
cord-267965-84sotgds	19	8	the	the	DT
cord-267965-84sotgds	19	9	existence	existence	NN
cord-267965-84sotgds	19	10	of	of	IN
cord-267965-84sotgds	19	11	inbred	inbred	JJ
cord-267965-84sotgds	19	12	mouse	mouse	NN
cord-267965-84sotgds	19	13	strains	strain	NNS
cord-267965-84sotgds	19	14	as	as	RB
cord-267965-84sotgds	19	15	well	well	RB
cord-267965-84sotgds	19	16	as	as	IN
cord-267965-84sotgds	19	17	the	the	DT
cord-267965-84sotgds	19	18	vast	vast	JJ
cord-267965-84sotgds	19	19	amount	amount	NN
cord-267965-84sotgds	19	20	of	of	IN
cord-267965-84sotgds	19	21	immunological	immunological	JJ
cord-267965-84sotgds	19	22	and	and	CC
cord-267965-84sotgds	19	23	molecular	molecular	JJ
cord-267965-84sotgds	19	24	genetic	genetic	JJ
cord-267965-84sotgds	19	25	tools	tool	NNS
cord-267965-84sotgds	19	26	available	available	JJ
cord-267965-84sotgds	19	27	for	for	IN
cord-267965-84sotgds	19	28	the	the	DT
cord-267965-84sotgds	19	29	mouse	mouse	NN
cord-267965-84sotgds	19	30	,	,	,
cord-267965-84sotgds	19	31	including	include	VBG
cord-267965-84sotgds	19	32	the	the	DT
cord-267965-84sotgds	19	33	early	early	JJ
cord-267965-84sotgds	19	34	generation	generation	NN
cord-267965-84sotgds	19	35	of	of	IN
cord-267965-84sotgds	19	36	the	the	DT
cord-267965-84sotgds	19	37	mouse	mouse	NN
cord-267965-84sotgds	19	38	reference	reference	NN
cord-267965-84sotgds	19	39	genome	genome	NN
cord-267965-84sotgds	19	40	.	.	.
cord-267965-84sotgds	20	1	Inbred	inbred	JJ
cord-267965-84sotgds	20	2	strains	strain	NNS
cord-267965-84sotgds	20	3	,	,	,
cord-267965-84sotgds	20	4	in	in	IN
cord-267965-84sotgds	20	5	which	which	WDT
cord-267965-84sotgds	20	6	each	each	DT
cord-267965-84sotgds	20	7	mouse	mouse	NN
cord-267965-84sotgds	20	8	is	be	VBZ
cord-267965-84sotgds	20	9	essentially	essentially	RB
cord-267965-84sotgds	20	10	genetically	genetically	RB
cord-267965-84sotgds	20	11	identical	identical	JJ
cord-267965-84sotgds	20	12	,	,	,
cord-267965-84sotgds	20	13	allow	allow	VB
cord-267965-84sotgds	20	14	control	control	NN
cord-267965-84sotgds	20	15	of	of	IN
cord-267965-84sotgds	20	16	host	host	NN
cord-267965-84sotgds	20	17	genetics	genetic	NNS
cord-267965-84sotgds	20	18	as	as	RB
cord-267965-84sotgds	20	19	well	well	RB
cord-267965-84sotgds	20	20	as	as	IN
cord-267965-84sotgds	20	21	other	other	JJ
cord-267965-84sotgds	20	22	factors	factor	NNS
cord-267965-84sotgds	20	23	that	that	WDT
cord-267965-84sotgds	20	24	can	can	MD
cord-267965-84sotgds	20	25	confound	confound	VB
cord-267965-84sotgds	20	26	human	human	JJ
cord-267965-84sotgds	20	27	studies	study	NNS
cord-267965-84sotgds	20	28	,	,	,
cord-267965-84sotgds	20	29	such	such	JJ
cord-267965-84sotgds	20	30	as	as	IN
cord-267965-84sotgds	20	31	pathogen	pathogen	NN
cord-267965-84sotgds	20	32	dose	dose	NN
cord-267965-84sotgds	20	33	,	,	,
cord-267965-84sotgds	20	34	nutrition	nutrition	NN
cord-267965-84sotgds	20	35	,	,	,
cord-267965-84sotgds	20	36	and	and	CC
cord-267965-84sotgds	20	37	prior	prior	JJ
cord-267965-84sotgds	20	38	immune	immune	JJ
cord-267965-84sotgds	20	39	exposure	exposure	NN
cord-267965-84sotgds	20	40	.	.	.
cord-267965-84sotgds	21	1	Additionally	additionally	RB
cord-267965-84sotgds	21	2	,	,	,
cord-267965-84sotgds	21	3	targeted	target	VBN
cord-267965-84sotgds	21	4	knockout	knockout	NN
cord-267965-84sotgds	21	5	technology	technology	NN
cord-267965-84sotgds	21	6	has	have	VBZ
cord-267965-84sotgds	21	7	been	be	VBN
cord-267965-84sotgds	21	8	used	use	VBN
cord-267965-84sotgds	21	9	in	in	IN
cord-267965-84sotgds	21	10	the	the	DT
cord-267965-84sotgds	21	11	mouse	mouse	NN
cord-267965-84sotgds	21	12	genome	genome	NN
cord-267965-84sotgds	21	13	for	for	IN
cord-267965-84sotgds	21	14	almost	almost	RB
cord-267965-84sotgds	21	15	30	30	CD
cord-267965-84sotgds	21	16	years	year	NNS
cord-267965-84sotgds	21	17	(	(	-LRB-
cord-267965-84sotgds	21	18	Bouabe	Bouabe	NNP
cord-267965-84sotgds	21	19	and	and	CC
cord-267965-84sotgds	21	20	Okkenhaug	Okkenhaug	NNP
cord-267965-84sotgds	21	21	,	,	,
cord-267965-84sotgds	21	22	2013	2013	CD
cord-267965-84sotgds	21	23	)	)	-RRB-
cord-267965-84sotgds	21	24	.	.	.
cord-267965-84sotgds	22	1	While	while	IN
cord-267965-84sotgds	22	2	advances	advance	NNS
cord-267965-84sotgds	22	3	in	in	IN
cord-267965-84sotgds	22	4	gene	gene	NN
cord-267965-84sotgds	22	5	editing	editing	NN
cord-267965-84sotgds	22	6	techniques	technique	NNS
cord-267965-84sotgds	22	7	(	(	-LRB-
cord-267965-84sotgds	22	8	e.g.	e.g.	RB
cord-267965-84sotgds	22	9	,	,	,
cord-267965-84sotgds	22	10	CRISPR	CRISPR	NNP
cord-267965-84sotgds	22	11	)	)	-RRB-
cord-267965-84sotgds	22	12	have	have	VBP
cord-267965-84sotgds	22	13	recently	recently	RB
cord-267965-84sotgds	22	14	extended	extend	VBN
cord-267965-84sotgds	22	15	these	these	DT
cord-267965-84sotgds	22	16	approaches	approach	NNS
cord-267965-84sotgds	22	17	to	to	IN
cord-267965-84sotgds	22	18	other	other	JJ
cord-267965-84sotgds	22	19	species	specie	NNS
cord-267965-84sotgds	22	20	,	,	,
cord-267965-84sotgds	22	21	genetically	genetically	RB
cord-267965-84sotgds	22	22	modified	modify	VBN
cord-267965-84sotgds	22	23	mice	mouse	NNS
cord-267965-84sotgds	22	24	have	have	VBP
cord-267965-84sotgds	22	25	been	be	VBN
cord-267965-84sotgds	22	26	an	an	DT
cord-267965-84sotgds	22	27	unparalleled	unparalleled	JJ
cord-267965-84sotgds	22	28	resource	resource	NN
cord-267965-84sotgds	22	29	for	for	IN
cord-267965-84sotgds	22	30	studying	study	VBG
cord-267965-84sotgds	22	31	the	the	DT
cord-267965-84sotgds	22	32	role	role	NN
cord-267965-84sotgds	22	33	of	of	IN
cord-267965-84sotgds	22	34	specific	specific	JJ
cord-267965-84sotgds	22	35	genes	gene	NNS
cord-267965-84sotgds	22	36	in	in	IN
cord-267965-84sotgds	22	37	the	the	DT
cord-267965-84sotgds	22	38	response	response	NN
cord-267965-84sotgds	22	39	to	to	IN
cord-267965-84sotgds	22	40	a	a	DT
cord-267965-84sotgds	22	41	variety	variety	NN
cord-267965-84sotgds	22	42	of	of	IN
cord-267965-84sotgds	22	43	pathogens	pathogen	NNS
cord-267965-84sotgds	23	1	(	(	-LRB-
cord-267965-84sotgds	23	2	Masopust	Masopust	NNP
cord-267965-84sotgds	23	3	et	et	NNP
cord-267965-84sotgds	23	4	al	al	NNP
cord-267965-84sotgds	23	5	.	.	NNP
cord-267965-84sotgds	23	6	,	,	,
cord-267965-84sotgds	23	7	2017	2017	CD
cord-267965-84sotgds	23	8	)	)	-RRB-
cord-267965-84sotgds	23	9	.	.	.
cord-267965-84sotgds	24	1	Furthermore	furthermore	RB
cord-267965-84sotgds	24	2	,	,	,
cord-267965-84sotgds	24	3	the	the	DT
cord-267965-84sotgds	24	4	use	use	NN
cord-267965-84sotgds	24	5	of	of	IN
cord-267965-84sotgds	24	6	classical	classical	JJ
cord-267965-84sotgds	24	7	genetic	genetic	JJ
cord-267965-84sotgds	24	8	crossing	crossing	NN
cord-267965-84sotgds	24	9	approaches	approach	NNS
cord-267965-84sotgds	24	10	(	(	-LRB-
cord-267965-84sotgds	24	11	e.g.	e.g.	RB
cord-267965-84sotgds	24	12	,	,	,
cord-267965-84sotgds	24	13	intercrosses	intercrosses	NNP
cord-267965-84sotgds	24	14	)	)	-RRB-
cord-267965-84sotgds	24	15	,	,	,
cord-267965-84sotgds	24	16	as	as	RB
cord-267965-84sotgds	24	17	well	well	RB
cord-267965-84sotgds	24	18	as	as	IN
cord-267965-84sotgds	24	19	reproducible	reproducible	JJ
cord-267965-84sotgds	24	20	mouse	mouse	NN
cord-267965-84sotgds	24	21	genetic	genetic	JJ
cord-267965-84sotgds	24	22	reference	reference	NN
cord-267965-84sotgds	24	23	populations	population	NNS
cord-267965-84sotgds	24	24	(	(	-LRB-
cord-267965-84sotgds	24	25	GRPs	GRPs	NNP
cord-267965-84sotgds	24	26	)	)	-RRB-
cord-267965-84sotgds	24	27	,	,	,
cord-267965-84sotgds	24	28	has	have	VBZ
cord-267965-84sotgds	24	29	facilitated	facilitate	VBN
cord-267965-84sotgds	24	30	the	the	DT
cord-267965-84sotgds	24	31	discovery	discovery	NN
cord-267965-84sotgds	24	32	of	of	IN
cord-267965-84sotgds	24	33	key	key	JJ
cord-267965-84sotgds	24	34	regulators	regulator	NNS
cord-267965-84sotgds	24	35	of	of	IN
cord-267965-84sotgds	24	36	host	host	NN
cord-267965-84sotgds	24	37	immunity	immunity	NN
cord-267965-84sotgds	24	38	and	and	CC
cord-267965-84sotgds	24	39	pathogen	pathogen	NN
cord-267965-84sotgds	24	40	susceptibility	susceptibility	NN
cord-267965-84sotgds	24	41	such	such	JJ
cord-267965-84sotgds	24	42	as	as	IN
cord-267965-84sotgds	24	43	the	the	DT
cord-267965-84sotgds	24	44	innate	innate	JJ
cord-267965-84sotgds	24	45	immune	immune	JJ
cord-267965-84sotgds	24	46	receptor	receptor	NN
cord-267965-84sotgds	24	47	Tlr4	Tlr4	NNP
cord-267965-84sotgds	24	48	,	,	,
cord-267965-84sotgds	24	49	oligoadenylate	oligoadenylate	NN
cord-267965-84sotgds	24	50	-	-	HYPH
cord-267965-84sotgds	24	51	synthetase	synthetase	NN
cord-267965-84sotgds	24	52	Oas1b	oas1b	NN
cord-267965-84sotgds	24	53	,	,	,
cord-267965-84sotgds	24	54	and	and	CC
cord-267965-84sotgds	24	55	divalent	divalent	JJ
cord-267965-84sotgds	24	56	metal	metal	NN
cord-267965-84sotgds	24	57	transporter	transporter	NN
cord-267965-84sotgds	24	58	Nramp1	Nramp1	NNP
cord-267965-84sotgds	25	1	(	(	-LRB-
cord-267965-84sotgds	25	2	Perelygin	Perelygin	NNP
cord-267965-84sotgds	25	3	et	et	FW
cord-267965-84sotgds	25	4	al	al	NNP
cord-267965-84sotgds	25	5	.	.	.
cord-267965-84sotgds	26	1	,	,	,
cord-267965-84sotgds	26	2	2002	2002	CD
cord-267965-84sotgds	26	3	;	;	:
cord-267965-84sotgds	26	4	Qureshi	Qureshi	NNP
cord-267965-84sotgds	26	5	et	et	NNP
cord-267965-84sotgds	26	6	al	al	NNP
cord-267965-84sotgds	26	7	.	.	.
cord-267965-84sotgds	27	1	,	,	,
cord-267965-84sotgds	27	2	1999	1999	CD
cord-267965-84sotgds	27	3	;	;	:
cord-267965-84sotgds	27	4	Vidal	Vidal	NNP
cord-267965-84sotgds	27	5	et	et	NNP
cord-267965-84sotgds	27	6	al	al	NNP
cord-267965-84sotgds	27	7	.	.	NNP
cord-267965-84sotgds	27	8	,	,	,
cord-267965-84sotgds	27	9	1993	1993	CD
cord-267965-84sotgds	27	10	)	)	-RRB-
cord-267965-84sotgds	27	11	.	.	.
cord-267965-84sotgds	28	1	The	the	DT
cord-267965-84sotgds	28	2	recent	recent	JJ
cord-267965-84sotgds	28	3	development	development	NN
cord-267965-84sotgds	28	4	of	of	IN
cord-267965-84sotgds	28	5	multiparental	multiparental	NNP
cord-267965-84sotgds	28	6	GRPs	GRPs	NNP
cord-267965-84sotgds	28	7	,	,	,
cord-267965-84sotgds	28	8	such	such	JJ
cord-267965-84sotgds	28	9	as	as	IN
cord-267965-84sotgds	28	10	the	the	DT
cord-267965-84sotgds	28	11	Collaborative	Collaborative	NNP
cord-267965-84sotgds	28	12	Cross	Cross	NNP
cord-267965-84sotgds	28	13	(	(	-LRB-
cord-267965-84sotgds	28	14	CC	CC	NNP
cord-267965-84sotgds	28	15	)	)	-RRB-
cord-267965-84sotgds	28	16	,	,	,
cord-267965-84sotgds	28	17	promises	promise	VBZ
cord-267965-84sotgds	28	18	to	to	TO
cord-267965-84sotgds	28	19	further	further	RB
cord-267965-84sotgds	28	20	extend	extend	VB
cord-267965-84sotgds	28	21	genetic	genetic	JJ
cord-267965-84sotgds	28	22	mapping	mapping	NN
cord-267965-84sotgds	28	23	capabilities	capability	NNS
cord-267965-84sotgds	28	24	,	,	,
cord-267965-84sotgds	28	25	while	while	IN
cord-267965-84sotgds	28	26	also	also	RB
cord-267965-84sotgds	28	27	leading	lead	VBG
cord-267965-84sotgds	28	28	to	to	IN
cord-267965-84sotgds	28	29	the	the	DT
cord-267965-84sotgds	28	30	development	development	NN
cord-267965-84sotgds	28	31	of	of	IN
cord-267965-84sotgds	28	32	mouse	mouse	NN
cord-267965-84sotgds	28	33	models	model	NNS
cord-267965-84sotgds	28	34	that	that	WDT
cord-267965-84sotgds	28	35	more	more	RBR
cord-267965-84sotgds	28	36	accurately	accurately	RB
cord-267965-84sotgds	28	37	reproduce	reproduce	VB
cord-267965-84sotgds	28	38	the	the	DT
cord-267965-84sotgds	28	39	genetic	genetic	JJ
cord-267965-84sotgds	28	40	diversity	diversity	NN
cord-267965-84sotgds	28	41	and	and	CC
cord-267965-84sotgds	28	42	phenotypic	phenotypic	JJ
cord-267965-84sotgds	28	43	range	range	NN
cord-267965-84sotgds	28	44	seen	see	VBN
cord-267965-84sotgds	28	45	in	in	IN
cord-267965-84sotgds	28	46	human	human	JJ
cord-267965-84sotgds	28	47	populations	population	NNS
cord-267965-84sotgds	29	1	(	(	-LRB-
cord-267965-84sotgds	29	2	Churchill	Churchill	NNP
cord-267965-84sotgds	29	3	et	et	NNP
cord-267965-84sotgds	29	4	al	al	NNP
cord-267965-84sotgds	29	5	.	.	NNP
cord-267965-84sotgds	29	6	,	,	,
cord-267965-84sotgds	29	7	2004	2004	CD
cord-267965-84sotgds	29	8	)	)	-RRB-
cord-267965-84sotgds	29	9	.	.	.
cord-267965-84sotgds	30	1	This	this	DT
cord-267965-84sotgds	30	2	review	review	NN
cord-267965-84sotgds	30	3	will	will	MD
cord-267965-84sotgds	30	4	summarize	summarize	VB
cord-267965-84sotgds	30	5	recent	recent	JJ
cord-267965-84sotgds	30	6	advances	advance	NNS
cord-267965-84sotgds	30	7	in	in	IN
cord-267965-84sotgds	30	8	the	the	DT
cord-267965-84sotgds	30	9	use	use	NN
cord-267965-84sotgds	30	10	of	of	IN
cord-267965-84sotgds	30	11	mouse	mouse	NN
cord-267965-84sotgds	30	12	GRPs	grp	NNS
cord-267965-84sotgds	30	13	,	,	,
cord-267965-84sotgds	30	14	with	with	IN
cord-267965-84sotgds	30	15	an	an	DT
cord-267965-84sotgds	30	16	emphasis	emphasis	NN
cord-267965-84sotgds	30	17	on	on	IN
cord-267965-84sotgds	30	18	the	the	DT
cord-267965-84sotgds	30	19	use	use	NN
cord-267965-84sotgds	30	20	of	of	IN
cord-267965-84sotgds	30	21	the	the	DT
cord-267965-84sotgds	30	22	CC	CC	NNP
cord-267965-84sotgds	30	23	for	for	IN
cord-267965-84sotgds	30	24	studying	study	VBG
cord-267965-84sotgds	30	25	infectious	infectious	JJ
cord-267965-84sotgds	30	26	diseases	disease	NNS
cord-267965-84sotgds	30	27	and	and	CC
cord-267965-84sotgds	30	28	immunity	immunity	NN
cord-267965-84sotgds	30	29	.	.	.
cord-267965-84sotgds	31	1	The	the	DT
cord-267965-84sotgds	31	2	impact	impact	NN
cord-267965-84sotgds	31	3	of	of	IN
cord-267965-84sotgds	31	4	host	host	NN
cord-267965-84sotgds	31	5	genetics	genetics	NN
cord-267965-84sotgds	31	6	on	on	IN
cord-267965-84sotgds	31	7	pathogen	pathogen	NN
cord-267965-84sotgds	31	8	susceptibility	susceptibility	NN
cord-267965-84sotgds	31	9	can	can	MD
cord-267965-84sotgds	31	10	be	be	VB
cord-267965-84sotgds	31	11	illustrated	illustrate	VBN
cord-267965-84sotgds	31	12	by	by	IN
cord-267965-84sotgds	31	13	genes	gene	NNS
cord-267965-84sotgds	31	14	exhibiting	exhibit	VBG
cord-267965-84sotgds	31	15	large	large	JJ
cord-267965-84sotgds	31	16	effects	effect	NNS
cord-267965-84sotgds	31	17	such	such	JJ
cord-267965-84sotgds	31	18	as	as	IN
cord-267965-84sotgds	31	19	the	the	DT
cord-267965-84sotgds	31	20	chemokine	chemokine	NN
cord-267965-84sotgds	31	21	receptor	receptor	NN
cord-267965-84sotgds	31	22	CCR5	CCR5	NNP
cord-267965-84sotgds	31	23	and	and	CC
cord-267965-84sotgds	31	24	fucosyltransferase	fucosyltransferase	CC
cord-267965-84sotgds	31	25	2	2	LS
cord-267965-84sotgds	31	26	(	(	-LRB-
cord-267965-84sotgds	31	27	FUT2	FUT2	NNP
cord-267965-84sotgds	31	28	)	)	-RRB-
cord-267965-84sotgds	31	29	,	,	,
cord-267965-84sotgds	31	30	for	for	IN
cord-267965-84sotgds	31	31	which	which	WDT
cord-267965-84sotgds	31	32	specific	specific	JJ
cord-267965-84sotgds	31	33	variants	variant	NNS
cord-267965-84sotgds	31	34	have	have	VBP
cord-267965-84sotgds	31	35	a	a	DT
cord-267965-84sotgds	31	36	major	major	JJ
cord-267965-84sotgds	31	37	impact	impact	NN
cord-267965-84sotgds	31	38	on	on	IN
cord-267965-84sotgds	31	39	resistance	resistance	NN
cord-267965-84sotgds	31	40	to	to	IN
cord-267965-84sotgds	31	41	viral	viral	JJ
cord-267965-84sotgds	31	42	infection	infection	NN
cord-267965-84sotgds	31	43	(	(	-LRB-
cord-267965-84sotgds	31	44	HIV	HIV	NNP
cord-267965-84sotgds	31	45	and	and	CC
cord-267965-84sotgds	31	46	norovirus	norovirus	NN
cord-267965-84sotgds	31	47	,	,	,
cord-267965-84sotgds	31	48	respectively	respectively	RB
cord-267965-84sotgds	31	49	)	)	-RRB-
cord-267965-84sotgds	32	1	(	(	-LRB-
cord-267965-84sotgds	32	2	Quillent	Quillent	NNP
cord-267965-84sotgds	32	3	et	et	NNP
cord-267965-84sotgds	32	4	al	al	NNP
cord-267965-84sotgds	32	5	.	.	NNP
cord-267965-84sotgds	32	6	,	,	,
cord-267965-84sotgds	32	7	1998	1998	CD
cord-267965-84sotgds	32	8	;	;	:
cord-267965-84sotgds	32	9	Thorven	Thorven	NNP
cord-267965-84sotgds	32	10	et	et	FW
cord-267965-84sotgds	32	11	al	al	NNP
cord-267965-84sotgds	32	12	.	.	NNP
cord-267965-84sotgds	32	13	,	,	,
cord-267965-84sotgds	32	14	2005	2005	CD
cord-267965-84sotgds	32	15	)	)	-RRB-
cord-267965-84sotgds	32	16	.	.	.
cord-267965-84sotgds	33	1	Likewise	likewise	RB
cord-267965-84sotgds	33	2	,	,	,
cord-267965-84sotgds	33	3	deleterious	deleterious	JJ
cord-267965-84sotgds	33	4	mutations	mutation	NNS
cord-267965-84sotgds	33	5	in	in	IN
cord-267965-84sotgds	33	6	immune	immune	JJ
cord-267965-84sotgds	33	7	genes	gene	NNS
cord-267965-84sotgds	33	8	can	can	MD
cord-267965-84sotgds	33	9	result	result	VB
cord-267965-84sotgds	33	10	in	in	IN
cord-267965-84sotgds	33	11	PIDs	pid	NNS
cord-267965-84sotgds	33	12	,	,	,
cord-267965-84sotgds	33	13	which	which	WDT
cord-267965-84sotgds	33	14	cause	cause	VBP
cord-267965-84sotgds	33	15	enhanced	enhanced	JJ
cord-267965-84sotgds	33	16	susceptibility	susceptibility	NN
cord-267965-84sotgds	33	17	to	to	IN
cord-267965-84sotgds	33	18	specific	specific	JJ
cord-267965-84sotgds	33	19	or	or	CC
cord-267965-84sotgds	33	20	entire	entire	JJ
cord-267965-84sotgds	33	21	classes	class	NNS
cord-267965-84sotgds	33	22	of	of	IN
cord-267965-84sotgds	33	23	pathogens	pathogen	NNS
cord-267965-84sotgds	34	1	(	(	-LRB-
cord-267965-84sotgds	34	2	Carneiro	Carneiro	NNP
cord-267965-84sotgds	34	3	-	-	HYPH
cord-267965-84sotgds	34	4	Sampaio	Sampaio	NNP
cord-267965-84sotgds	34	5	and	and	CC
cord-267965-84sotgds	34	6	Coutinho	Coutinho	NNP
cord-267965-84sotgds	34	7	,	,	,
cord-267965-84sotgds	34	8	2007	2007	CD
cord-267965-84sotgds	34	9	)	)	-RRB-
cord-267965-84sotgds	34	10	.	.	.
cord-267965-84sotgds	35	1	To	to	IN
cord-267965-84sotgds	35	2	date	date	NN
cord-267965-84sotgds	35	3	,	,	,
cord-267965-84sotgds	35	4	over	over	IN
cord-267965-84sotgds	35	5	350	350	CD
cord-267965-84sotgds	35	6	genetically	genetically	RB
cord-267965-84sotgds	35	7	driven	drive	VBN
cord-267965-84sotgds	35	8	PIDs	pid	NNS
cord-267965-84sotgds	35	9	have	have	VBP
cord-267965-84sotgds	35	10	been	be	VBN
cord-267965-84sotgds	35	11	identified	identify	VBN
cord-267965-84sotgds	35	12	in	in	IN
cord-267965-84sotgds	35	13	humans	human	NNS
cord-267965-84sotgds	35	14	(	(	-LRB-
cord-267965-84sotgds	35	15	Picard	Picard	NNP
cord-267965-84sotgds	35	16	et	et	NNP
cord-267965-84sotgds	35	17	al	al	NNP
cord-267965-84sotgds	35	18	.	.	NNP
cord-267965-84sotgds	35	19	,	,	,
cord-267965-84sotgds	35	20	2018	2018	CD
cord-267965-84sotgds	35	21	)	)	-RRB-
cord-267965-84sotgds	35	22	.	.	.
cord-267965-84sotgds	36	1	The	the	DT
cord-267965-84sotgds	36	2	identification	identification	NN
cord-267965-84sotgds	36	3	of	of	IN
cord-267965-84sotgds	36	4	these	these	DT
cord-267965-84sotgds	36	5	monogenic	monogenic	NNP
cord-267965-84sotgds	36	6	resistance	resistance	NN
cord-267965-84sotgds	36	7	and	and	CC
cord-267965-84sotgds	36	8	susceptibility	susceptibility	NN
cord-267965-84sotgds	36	9	genes	gene	NNS
cord-267965-84sotgds	36	10	has	have	VBZ
cord-267965-84sotgds	36	11	enhanced	enhance	VBN
cord-267965-84sotgds	36	12	our	-PRON-	PRP$
cord-267965-84sotgds	36	13	understanding	understanding	NN
cord-267965-84sotgds	36	14	of	of	IN
cord-267965-84sotgds	36	15	human	human	JJ
cord-267965-84sotgds	36	16	immunity	immunity	NN
cord-267965-84sotgds	36	17	and	and	CC
cord-267965-84sotgds	36	18	hostpathogen	hostpathogen	NNP
cord-267965-84sotgds	36	19	interactions	interaction	NNS
cord-267965-84sotgds	36	20	while	while	IN
cord-267965-84sotgds	36	21	contributing	contribute	VBG
cord-267965-84sotgds	36	22	to	to	IN
cord-267965-84sotgds	36	23	the	the	DT
cord-267965-84sotgds	36	24	development	development	NN
cord-267965-84sotgds	36	25	of	of	IN
cord-267965-84sotgds	36	26	antiviral	antiviral	JJ
cord-267965-84sotgds	36	27	therapies	therapy	NNS
cord-267965-84sotgds	36	28	,	,	,
cord-267965-84sotgds	36	29	such	such	JJ
cord-267965-84sotgds	36	30	as	as	IN
cord-267965-84sotgds	36	31	HIV	HIV	NNP
cord-267965-84sotgds	36	32	entry	entry	NN
cord-267965-84sotgds	36	33	inhibitors	inhibitor	NNS
cord-267965-84sotgds	36	34	,	,	,
cord-267965-84sotgds	36	35	as	as	RB
cord-267965-84sotgds	36	36	well	well	RB
cord-267965-84sotgds	36	37	as	as	IN
cord-267965-84sotgds	36	38	gene	gene	NN
cord-267965-84sotgds	36	39	therapy	therapy	NN
cord-267965-84sotgds	36	40	and	and	CC
cord-267965-84sotgds	36	41	immune	immune	JJ
cord-267965-84sotgds	36	42	replacement	replacement	NN
cord-267965-84sotgds	36	43	therapies	therapy	NNS
cord-267965-84sotgds	36	44	(	(	-LRB-
cord-267965-84sotgds	36	45	Collins	Collins	NNP
cord-267965-84sotgds	36	46	and	and	CC
cord-267965-84sotgds	36	47	Thrasher	Thrasher	NNP
cord-267965-84sotgds	36	48	,	,	,
cord-267965-84sotgds	36	49	2015	2015	CD
cord-267965-84sotgds	36	50	;	;	:
cord-267965-84sotgds	36	51	Lenardo	Lenardo	NNP
cord-267965-84sotgds	36	52	et	et	NNP
cord-267965-84sotgds	36	53	al	al	NNP
cord-267965-84sotgds	36	54	.	.	NNP
cord-267965-84sotgds	36	55	,	,	,
cord-267965-84sotgds	36	56	2016	2016	CD
cord-267965-84sotgds	36	57	)	)	-RRB-
cord-267965-84sotgds	36	58	.	.	.
cord-267965-84sotgds	37	1	Though	though	IN
cord-267965-84sotgds	37	2	genes	gene	NNS
cord-267965-84sotgds	37	3	of	of	IN
cord-267965-84sotgds	37	4	large	large	JJ
cord-267965-84sotgds	37	5	effect	effect	NN
cord-267965-84sotgds	37	6	can	can	MD
cord-267965-84sotgds	37	7	impact	impact	VB
cord-267965-84sotgds	37	8	human	human	JJ
cord-267965-84sotgds	37	9	health	health	NN
cord-267965-84sotgds	37	10	,	,	,
cord-267965-84sotgds	37	11	inheritance	inheritance	NN
cord-267965-84sotgds	37	12	patterns	pattern	NNS
cord-267965-84sotgds	37	13	suggest	suggest	VBP
cord-267965-84sotgds	37	14	that	that	IN
cord-267965-84sotgds	37	15	susceptibility	susceptibility	NN
cord-267965-84sotgds	37	16	to	to	IN
cord-267965-84sotgds	37	17	infectious	infectious	JJ
cord-267965-84sotgds	37	18	disease	disease	NN
cord-267965-84sotgds	37	19	is	be	VBZ
cord-267965-84sotgds	37	20	largely	largely	RB
cord-267965-84sotgds	37	21	polygenic	polygenic	JJ
cord-267965-84sotgds	37	22	(	(	-LRB-
cord-267965-84sotgds	37	23	driven	drive	VBN
cord-267965-84sotgds	37	24	by	by	IN
cord-267965-84sotgds	37	25	tens	ten	NNS
cord-267965-84sotgds	37	26	to	to	IN
cord-267965-84sotgds	37	27	thousands	thousand	NNS
cord-267965-84sotgds	37	28	of	of	IN
cord-267965-84sotgds	37	29	variants	variant	NNS
cord-267965-84sotgds	37	30	of	of	IN
cord-267965-84sotgds	37	31	smaller	small	JJR
cord-267965-84sotgds	37	32	effect	effect	NN
cord-267965-84sotgds	37	33	)	)	-RRB-
cord-267965-84sotgds	38	1	(	(	-LRB-
cord-267965-84sotgds	38	2	Hill	Hill	NNP
cord-267965-84sotgds	38	3	,	,	,
cord-267965-84sotgds	38	4	2012	2012	CD
cord-267965-84sotgds	38	5	)	)	-RRB-
cord-267965-84sotgds	38	6	.	.	.
cord-267965-84sotgds	39	1	This	this	DT
cord-267965-84sotgds	39	2	is	be	VBZ
cord-267965-84sotgds	39	3	supported	support	VBN
cord-267965-84sotgds	39	4	by	by	IN
cord-267965-84sotgds	39	5	results	result	NNS
cord-267965-84sotgds	39	6	from	from	IN
cord-267965-84sotgds	39	7	genome	genome	NN
cord-267965-84sotgds	39	8	-	-	HYPH
cord-267965-84sotgds	39	9	wide	wide	JJ
cord-267965-84sotgds	39	10	association	association	NN
cord-267965-84sotgds	39	11	studies	study	NNS
cord-267965-84sotgds	39	12	(	(	-LRB-
cord-267965-84sotgds	39	13	GWAS	GWAS	NNP
cord-267965-84sotgds	39	14	)	)	-RRB-
cord-267965-84sotgds	39	15	designed	design	VBN
cord-267965-84sotgds	39	16	to	to	TO
cord-267965-84sotgds	39	17	map	map	VB
cord-267965-84sotgds	39	18	loci	locus	NNS
cord-267965-84sotgds	39	19	associated	associate	VBN
cord-267965-84sotgds	39	20	with	with	IN
cord-267965-84sotgds	39	21	variation	variation	NN
cord-267965-84sotgds	39	22	in	in	IN
cord-267965-84sotgds	39	23	pathogen	pathogen	NN
cord-267965-84sotgds	39	24	susceptibility	susceptibility	NN
cord-267965-84sotgds	39	25	and	and	CC
cord-267965-84sotgds	39	26	vaccine	vaccine	NN
cord-267965-84sotgds	39	27	response	response	NN
cord-267965-84sotgds	39	28	.	.	.
cord-267965-84sotgds	40	1	For	for	IN
cord-267965-84sotgds	40	2	example	example	NN
cord-267965-84sotgds	40	3	,	,	,
cord-267965-84sotgds	40	4	GWAS	GWAS	NNP
cord-267965-84sotgds	40	5	of	of	IN
cord-267965-84sotgds	40	6	HIV	HIV	NNP
cord-267965-84sotgds	40	7	viral	viral	JJ
cord-267965-84sotgds	40	8	load	load	NN
cord-267965-84sotgds	40	9	have	have	VBP
cord-267965-84sotgds	40	10	shown	show	VBN
cord-267965-84sotgds	40	11	that	that	IN
cord-267965-84sotgds	40	12	mutations	mutation	NNS
cord-267965-84sotgds	40	13	in	in	IN
cord-267965-84sotgds	40	14	the	the	DT
cord-267965-84sotgds	40	15	HIV	HIV	NNP
cord-267965-84sotgds	40	16	co	co	NN
cord-267965-84sotgds	40	17	-	-	NN
cord-267965-84sotgds	40	18	receptor	receptor	NN
cord-267965-84sotgds	40	19	CCR5	CCR5	NNP
cord-267965-84sotgds	40	20	and	and	CC
cord-267965-84sotgds	40	21	variants	variant	NNS
cord-267965-84sotgds	40	22	in	in	IN
cord-267965-84sotgds	40	23	human	human	JJ
cord-267965-84sotgds	40	24	leukocyte	leukocyte	NN
cord-267965-84sotgds	40	25	antigen	antigen	NN
cord-267965-84sotgds	40	26	(	(	-LRB-
cord-267965-84sotgds	40	27	HLA	HLA	NNP
cord-267965-84sotgds	40	28	)	)	-RRB-
cord-267965-84sotgds	40	29	explain	explain	VBP
cord-267965-84sotgds	40	30	approximately	approximately	RB
cord-267965-84sotgds	40	31	15	15	CD
cord-267965-84sotgds	40	32	%	%	NN
cord-267965-84sotgds	40	33	of	of	IN
cord-267965-84sotgds	40	34	the	the	DT
cord-267965-84sotgds	40	35	total	total	JJ
cord-267965-84sotgds	40	36	variance	variance	NN
cord-267965-84sotgds	40	37	,	,	,
cord-267965-84sotgds	40	38	with	with	IN
cord-267965-84sotgds	40	39	an	an	DT
cord-267965-84sotgds	40	40	additional	additional	JJ
cord-267965-84sotgds	40	41	5	5	CD
cord-267965-84sotgds	40	42	%	%	NN
cord-267965-84sotgds	40	43	of	of	IN
cord-267965-84sotgds	40	44	heritable	heritable	JJ
cord-267965-84sotgds	40	45	variance	variance	NN
cord-267965-84sotgds	40	46	explained	explain	VBN
cord-267965-84sotgds	40	47	by	by	IN
cord-267965-84sotgds	40	48	additive	additive	NN
cord-267965-84sotgds	40	49	effects	effect	NNS
cord-267965-84sotgds	40	50	of	of	IN
cord-267965-84sotgds	40	51	other	other	JJ
cord-267965-84sotgds	40	52	genes	gene	NNS
cord-267965-84sotgds	40	53	(	(	-LRB-
cord-267965-84sotgds	40	54	McLaren	McLaren	NNP
cord-267965-84sotgds	40	55	et	et	NNP
cord-267965-84sotgds	40	56	al	al	NNP
cord-267965-84sotgds	40	57	.	.	NNP
cord-267965-84sotgds	40	58	,	,	,
cord-267965-84sotgds	40	59	2015	2015	CD
cord-267965-84sotgds	40	60	)	)	-RRB-
cord-267965-84sotgds	40	61	.	.	.
cord-267965-84sotgds	41	1	GWAS	GWAS	NNP
cord-267965-84sotgds	41	2	on	on	IN
cord-267965-84sotgds	41	3	malaria	malaria	NN
cord-267965-84sotgds	41	4	susceptibility	susceptibility	NN
cord-267965-84sotgds	41	5	have	have	VBP
cord-267965-84sotgds	41	6	identified	identify	VBN
cord-267965-84sotgds	41	7	variants	variant	NNS
cord-267965-84sotgds	41	8	in	in	IN
cord-267965-84sotgds	41	9	multiple	multiple	JJ
cord-267965-84sotgds	41	10	genes	gene	NNS
cord-267965-84sotgds	41	11	including	include	VBG
cord-267965-84sotgds	41	12	the	the	DT
cord-267965-84sotgds	41	13	calcium	calcium	NN
cord-267965-84sotgds	41	14	ATPase	ATPase	NNP
cord-267965-84sotgds	41	15	ATP2B4	ATP2B4	NNP
cord-267965-84sotgds	41	16	,	,	,
cord-267965-84sotgds	41	17	the	the	DT
cord-267965-84sotgds	41	18	glucose	glucose	NN
cord-267965-84sotgds	41	19	phosphate	phosphate	NN
cord-267965-84sotgds	41	20	dehydrogenase	dehydrogenase	NN
cord-267965-84sotgds	41	21	GP6D	GP6D	NNP
cord-267965-84sotgds	41	22	,	,	,
cord-267965-84sotgds	41	23	and	and	CC
cord-267965-84sotgds	41	24	HLAs	HLAs	NNP
cord-267965-84sotgds	41	25	,	,	,
cord-267965-84sotgds	41	26	as	as	RB
cord-267965-84sotgds	41	27	well	well	RB
cord-267965-84sotgds	41	28	as	as	IN
cord-267965-84sotgds	41	29	confirming	confirm	VBG
cord-267965-84sotgds	41	30	previously	previously	RB
cord-267965-84sotgds	41	31	identified	identify	VBN
cord-267965-84sotgds	41	32	variants	variant	NNS
cord-267965-84sotgds	41	33	in	in	IN
cord-267965-84sotgds	41	34	hemoglobin	hemoglobin	NN
cord-267965-84sotgds	41	35	genes	gene	NNS
cord-267965-84sotgds	41	36	(	(	-LRB-
cord-267965-84sotgds	41	37	sickle	sickle	NN
cord-267965-84sotgds	41	38	cell	cell	NN
cord-267965-84sotgds	41	39	and	and	CC
cord-267965-84sotgds	41	40	thalassemia	thalassemia	NN
cord-267965-84sotgds	41	41	)	)	-RRB-
cord-267965-84sotgds	41	42	(	(	-LRB-
cord-267965-84sotgds	41	43	Hedrick	Hedrick	NNP
cord-267965-84sotgds	41	44	,	,	,
cord-267965-84sotgds	41	45	2011	2011	CD
cord-267965-84sotgds	41	46	;	;	:
cord-267965-84sotgds	42	1	Timmann	Timmann	NNP
cord-267965-84sotgds	42	2	et	et	NNP
cord-267965-84sotgds	42	3	al	al	NNP
cord-267965-84sotgds	42	4	.	.	NNP
cord-267965-84sotgds	42	5	,	,	,
cord-267965-84sotgds	42	6	2012	2012	CD
cord-267965-84sotgds	42	7	)	)	-RRB-
cord-267965-84sotgds	42	8	.	.	.
cord-267965-84sotgds	43	1	Multiple	multiple	JJ
cord-267965-84sotgds	43	2	loci	locus	NNS
cord-267965-84sotgds	43	3	have	have	VBP
cord-267965-84sotgds	43	4	been	be	VBN
cord-267965-84sotgds	43	5	associated	associate	VBN
cord-267965-84sotgds	43	6	with	with	IN
cord-267965-84sotgds	43	7	clearance	clearance	NN
cord-267965-84sotgds	43	8	of	of	IN
cord-267965-84sotgds	43	9	hepatitis	hepatitis	NN
cord-267965-84sotgds	43	10	C	C	NNP
cord-267965-84sotgds	43	11	virus	virus	NN
cord-267965-84sotgds	43	12	,	,	,
cord-267965-84sotgds	43	13	including	include	VBG
cord-267965-84sotgds	43	14	the	the	DT
cord-267965-84sotgds	43	15	cytokine	cytokine	NN
cord-267965-84sotgds	43	16	IL-28b	IL-28b	NNP
cord-267965-84sotgds	43	17	and	and	CC
cord-267965-84sotgds	43	18	HLA	HLA	NNP
cord-267965-84sotgds	43	19	genes	gene	NNS
cord-267965-84sotgds	43	20	(	(	-LRB-
cord-267965-84sotgds	43	21	Duggal	Duggal	NNP
cord-267965-84sotgds	43	22	et	et	FW
cord-267965-84sotgds	43	23	al	al	NNP
cord-267965-84sotgds	43	24	.	.	NNP
cord-267965-84sotgds	43	25	,	,	,
cord-267965-84sotgds	43	26	2013	2013	CD
cord-267965-84sotgds	43	27	)	)	-RRB-
cord-267965-84sotgds	43	28	,	,	,
cord-267965-84sotgds	43	29	and	and	CC
cord-267965-84sotgds	43	30	over	over	IN
cord-267965-84sotgds	43	31	20	20	CD
cord-267965-84sotgds	43	32	loci	locus	NNS
cord-267965-84sotgds	43	33	have	have	VBP
cord-267965-84sotgds	43	34	been	be	VBN
cord-267965-84sotgds	43	35	associated	associate	VBN
cord-267965-84sotgds	43	36	with	with	IN
cord-267965-84sotgds	43	37	leprosy	leprosy	NN
cord-267965-84sotgds	43	38	susceptibility	susceptibility	NN
cord-267965-84sotgds	43	39	(	(	-LRB-
cord-267965-84sotgds	43	40	Wang	Wang	NNP
cord-267965-84sotgds	43	41	et	et	NNP
cord-267965-84sotgds	43	42	al	al	NNP
cord-267965-84sotgds	43	43	.	.	NNP
cord-267965-84sotgds	43	44	,	,	,
cord-267965-84sotgds	43	45	2016	2016	CD
cord-267965-84sotgds	43	46	)	)	-RRB-
cord-267965-84sotgds	43	47	.	.	.
cord-267965-84sotgds	44	1	While	while	IN
cord-267965-84sotgds	44	2	GWAS	GWAS	NNP
cord-267965-84sotgds	44	3	have	have	VBP
cord-267965-84sotgds	44	4	been	be	VBN
cord-267965-84sotgds	44	5	applied	apply	VBN
cord-267965-84sotgds	44	6	to	to	IN
cord-267965-84sotgds	44	7	and	and	CC
cord-267965-84sotgds	44	8	enhanced	enhance	VBD
cord-267965-84sotgds	44	9	our	-PRON-	PRP$
cord-267965-84sotgds	44	10	understanding	understanding	NN
cord-267965-84sotgds	44	11	of	of	IN
cord-267965-84sotgds	44	12	infectious	infectious	JJ
cord-267965-84sotgds	44	13	diseases	disease	NNS
cord-267965-84sotgds	44	14	,	,	,
cord-267965-84sotgds	44	15	these	these	DT
cord-267965-84sotgds	44	16	studies	study	NNS
cord-267965-84sotgds	44	17	explain	explain	VBP
cord-267965-84sotgds	44	18	only	only	RB
cord-267965-84sotgds	44	19	a	a	DT
cord-267965-84sotgds	44	20	fraction	fraction	NN
cord-267965-84sotgds	44	21	of	of	IN
cord-267965-84sotgds	44	22	the	the	DT
cord-267965-84sotgds	44	23	heritable	heritable	JJ
cord-267965-84sotgds	44	24	variation	variation	NN
cord-267965-84sotgds	44	25	in	in	IN
cord-267965-84sotgds	44	26	pathogen	pathogen	NN
cord-267965-84sotgds	44	27	susceptibility	susceptibility	NN
cord-267965-84sotgds	44	28	(	(	-LRB-
cord-267965-84sotgds	44	29	Hill	Hill	NNP
cord-267965-84sotgds	44	30	,	,	,
cord-267965-84sotgds	44	31	2012	2012	CD
cord-267965-84sotgds	44	32	)	)	-RRB-
cord-267965-84sotgds	44	33	.	.	.
cord-267965-84sotgds	45	1	This	this	DT
cord-267965-84sotgds	45	2	is	be	VBZ
cord-267965-84sotgds	45	3	partly	partly	RB
cord-267965-84sotgds	45	4	attributable	attributable	JJ
cord-267965-84sotgds	45	5	to	to	IN
cord-267965-84sotgds	45	6	factors	factor	NNS
cord-267965-84sotgds	45	7	such	such	JJ
cord-267965-84sotgds	45	8	as	as	IN
cord-267965-84sotgds	45	9	small	small	JJ
cord-267965-84sotgds	45	10	cohort	cohort	NN
cord-267965-84sotgds	45	11	sizes	size	NNS
cord-267965-84sotgds	45	12	,	,	,
cord-267965-84sotgds	45	13	ethnic	ethnic	JJ
cord-267965-84sotgds	45	14	striations	striation	NNS
cord-267965-84sotgds	45	15	,	,	,
cord-267965-84sotgds	45	16	and	and	CC
cord-267965-84sotgds	45	17	lack	lack	NN
cord-267965-84sotgds	45	18	of	of	IN
cord-267965-84sotgds	45	19	replicates	replicate	NNS
cord-267965-84sotgds	45	20	,	,	,
cord-267965-84sotgds	45	21	which	which	WDT
cord-267965-84sotgds	45	22	limit	limit	VBP
cord-267965-84sotgds	45	23	detection	detection	NN
cord-267965-84sotgds	45	24	and	and	CC
cord-267965-84sotgds	45	25	interpretation	interpretation	NN
cord-267965-84sotgds	45	26	of	of	IN
cord-267965-84sotgds	45	27	results	result	NNS
cord-267965-84sotgds	45	28	(	(	-LRB-
cord-267965-84sotgds	45	29	Du	Du	NNP
cord-267965-84sotgds	45	30	et	et	FW
cord-267965-84sotgds	45	31	al	al	NNP
cord-267965-84sotgds	45	32	.	.	NNP
cord-267965-84sotgds	45	33	,	,	,
cord-267965-84sotgds	45	34	2012	2012	CD
cord-267965-84sotgds	45	35	)	)	-RRB-
cord-267965-84sotgds	45	36	.	.	.
cord-267965-84sotgds	46	1	Rare	rare	JJ
cord-267965-84sotgds	46	2	genetic	genetic	JJ
cord-267965-84sotgds	46	3	variants	variant	NNS
cord-267965-84sotgds	46	4	are	be	VBP
cord-267965-84sotgds	46	5	unlikely	unlikely	JJ
cord-267965-84sotgds	46	6	to	to	TO
cord-267965-84sotgds	46	7	be	be	VB
cord-267965-84sotgds	46	8	detected	detect	VBN
cord-267965-84sotgds	46	9	by	by	IN
cord-267965-84sotgds	46	10	GWAS	GWAS	NNP
cord-267965-84sotgds	46	11	,	,	,
cord-267965-84sotgds	46	12	due	due	IN
cord-267965-84sotgds	46	13	to	to	IN
cord-267965-84sotgds	46	14	both	both	DT
cord-267965-84sotgds	46	15	lack	lack	NN
cord-267965-84sotgds	46	16	of	of	IN
cord-267965-84sotgds	46	17	power	power	NN
cord-267965-84sotgds	46	18	and	and	CC
cord-267965-84sotgds	46	19	lack	lack	NN
cord-267965-84sotgds	46	20	of	of	IN
cord-267965-84sotgds	46	21	tagging	tagging	NN
cord-267965-84sotgds	46	22	on	on	IN
cord-267965-84sotgds	46	23	conventional	conventional	JJ
cord-267965-84sotgds	46	24	genotyping	genotyping	NN
cord-267965-84sotgds	46	25	arrays	array	NNS
cord-267965-84sotgds	46	26	(	(	-LRB-
cord-267965-84sotgds	46	27	Auer	Auer	NNP
cord-267965-84sotgds	46	28	and	and	CC
cord-267965-84sotgds	46	29	Lettre	Lettre	NNP
cord-267965-84sotgds	46	30	,	,	,
cord-267965-84sotgds	46	31	2015	2015	CD
cord-267965-84sotgds	46	32	)	)	-RRB-
cord-267965-84sotgds	46	33	.	.	.
cord-267965-84sotgds	47	1	A	a	DT
cord-267965-84sotgds	47	2	specific	specific	JJ
cord-267965-84sotgds	47	3	concern	concern	NN
cord-267965-84sotgds	47	4	for	for	IN
cord-267965-84sotgds	47	5	GWAS	GWAS	NNP
cord-267965-84sotgds	47	6	in	in	IN
cord-267965-84sotgds	47	7	infectious	infectious	JJ
cord-267965-84sotgds	47	8	diseases	disease	NNS
cord-267965-84sotgds	47	9	is	be	VBZ
cord-267965-84sotgds	47	10	that	that	IN
cord-267965-84sotgds	47	11	studies	study	NNS
cord-267965-84sotgds	47	12	can	can	MD
cord-267965-84sotgds	47	13	be	be	VB
cord-267965-84sotgds	47	14	confounded	confound	VBN
cord-267965-84sotgds	47	15	by	by	IN
cord-267965-84sotgds	47	16	pathogen	pathogen	NN
cord-267965-84sotgds	47	17	genetics	genetic	NNS
cord-267965-84sotgds	47	18	,	,	,
cord-267965-84sotgds	47	19	pathogen	pathogen	NN
cord-267965-84sotgds	47	20	dose	dose	NN
cord-267965-84sotgds	47	21	,	,	,
cord-267965-84sotgds	47	22	and	and	CC
cord-267965-84sotgds	47	23	other	other	JJ
cord-267965-84sotgds	47	24	environmental	environmental	JJ
cord-267965-84sotgds	47	25	factors	factor	NNS
cord-267965-84sotgds	47	26	.	.	.
cord-267965-84sotgds	48	1	Furthermore	furthermore	RB
cord-267965-84sotgds	48	2	,	,	,
cord-267965-84sotgds	48	3	validation	validation	NN
cord-267965-84sotgds	48	4	and	and	CC
cord-267965-84sotgds	48	5	mechanistic	mechanistic	JJ
cord-267965-84sotgds	48	6	analysis	analysis	NN
cord-267965-84sotgds	48	7	can	can	MD
cord-267965-84sotgds	48	8	be	be	VB
cord-267965-84sotgds	48	9	difficult	difficult	JJ
cord-267965-84sotgds	48	10	in	in	IN
cord-267965-84sotgds	48	11	humans	human	NNS
cord-267965-84sotgds	48	12	due	due	JJ
cord-267965-84sotgds	48	13	to	to	IN
cord-267965-84sotgds	48	14	factors	factor	NNS
cord-267965-84sotgds	48	15	such	such	JJ
cord-267965-84sotgds	48	16	as	as	IN
cord-267965-84sotgds	48	17	lack	lack	NN
cord-267965-84sotgds	48	18	of	of	IN
cord-267965-84sotgds	48	19	replicates	replicate	NNS
cord-267965-84sotgds	48	20	and	and	CC
cord-267965-84sotgds	48	21	inability	inability	NN
cord-267965-84sotgds	48	22	to	to	TO
cord-267965-84sotgds	48	23	routinely	routinely	RB
cord-267965-84sotgds	48	24	access	access	VB
cord-267965-84sotgds	48	25	many	many	JJ
cord-267965-84sotgds	48	26	affected	affect	VBN
cord-267965-84sotgds	48	27	tissue	tissue	NN
cord-267965-84sotgds	48	28	types	type	NNS
cord-267965-84sotgds	48	29	.	.	.
cord-267965-84sotgds	49	1	For	for	IN
cord-267965-84sotgds	49	2	these	these	DT
cord-267965-84sotgds	49	3	reasons	reason	NNS
cord-267965-84sotgds	49	4	,	,	,
cord-267965-84sotgds	49	5	the	the	DT
cord-267965-84sotgds	49	6	use	use	NN
cord-267965-84sotgds	49	7	of	of	IN
cord-267965-84sotgds	49	8	appropriate	appropriate	JJ
cord-267965-84sotgds	49	9	animal	animal	NN
cord-267965-84sotgds	49	10	models	model	NNS
cord-267965-84sotgds	49	11	has	have	VBZ
cord-267965-84sotgds	49	12	been	be	VBN
cord-267965-84sotgds	49	13	a	a	DT
cord-267965-84sotgds	49	14	critical	critical	JJ
cord-267965-84sotgds	49	15	resource	resource	NN
cord-267965-84sotgds	49	16	for	for	IN
cord-267965-84sotgds	49	17	identifying	identify	VBG
cord-267965-84sotgds	49	18	and	and	CC
cord-267965-84sotgds	49	19	studying	study	VBG
cord-267965-84sotgds	49	20	pathogen	pathogen	NN
cord-267965-84sotgds	49	21	susceptibility	susceptibility	NN
cord-267965-84sotgds	49	22	genes	gene	NNS
cord-267965-84sotgds	49	23	.	.	.
cord-267965-84sotgds	50	1	While	while	IN
cord-267965-84sotgds	50	2	a	a	DT
cord-267965-84sotgds	50	3	variety	variety	NN
cord-267965-84sotgds	50	4	of	of	IN
cord-267965-84sotgds	50	5	model	model	JJ
cord-267965-84sotgds	50	6	genetic	genetic	JJ
cord-267965-84sotgds	50	7	systems	system	NNS
cord-267965-84sotgds	50	8	have	have	VBP
cord-267965-84sotgds	50	9	been	be	VBN
cord-267965-84sotgds	50	10	used	use	VBN
cord-267965-84sotgds	50	11	to	to	TO
cord-267965-84sotgds	50	12	analyze	analyze	VB
cord-267965-84sotgds	50	13	host	host	NN
cord-267965-84sotgds	50	14	-	-	HYPH
cord-267965-84sotgds	50	15	pathogen	pathogen	NN
cord-267965-84sotgds	50	16	interactions	interaction	NNS
cord-267965-84sotgds	50	17	(	(	-LRB-
cord-267965-84sotgds	50	18	e.g.	e.g.	RB
cord-267965-84sotgds	50	19	,	,	,
cord-267965-84sotgds	50	20	Caenorhabditis	Caenorhabditis	NNP
cord-267965-84sotgds	50	21	elegans	elegan	NNS
cord-267965-84sotgds	50	22	,	,	,
cord-267965-84sotgds	50	23	Danio	Danio	NNP
cord-267965-84sotgds	50	24	rerio	rerio	NN
cord-267965-84sotgds	50	25	,	,	,
cord-267965-84sotgds	50	26	and	and	CC
cord-267965-84sotgds	50	27	Drosophila	Drosophila	NNP
cord-267965-84sotgds	50	28	melanogaster	melanogaster	NN
cord-267965-84sotgds	50	29	)	)	-RRB-
cord-267965-84sotgds	51	1	(	(	-LRB-
cord-267965-84sotgds	51	2	Allen	Allen	NNP
cord-267965-84sotgds	51	3	and	and	CC
cord-267965-84sotgds	51	4	Neely	Neely	NNP
cord-267965-84sotgds	51	5	,	,	,
cord-267965-84sotgds	51	6	2010	2010	CD
cord-267965-84sotgds	51	7	;	;	:
cord-267965-84sotgds	51	8	Dionne	Dionne	NNP
cord-267965-84sotgds	51	9	and	and	CC
cord-267965-84sotgds	51	10	Schneider	Schneider	NNP
cord-267965-84sotgds	51	11	,	,	,
cord-267965-84sotgds	51	12	2008	2008	CD
cord-267965-84sotgds	51	13	;	;	:
cord-267965-84sotgds	51	14	Marsh	Marsh	NNP
cord-267965-84sotgds	51	15	and	and	CC
cord-267965-84sotgds	51	16	May	May	NNP
cord-267965-84sotgds	51	17	,	,	,
cord-267965-84sotgds	51	18	2012	2012	CD
cord-267965-84sotgds	51	19	)	)	-RRB-
cord-267965-84sotgds	51	20	,	,	,
cord-267965-84sotgds	51	21	the	the	DT
cord-267965-84sotgds	51	22	laboratory	laboratory	NN
cord-267965-84sotgds	51	23	mouse	mouse	NN
cord-267965-84sotgds	51	24	(	(	-LRB-
cord-267965-84sotgds	51	25	Mus	Mus	NNP
cord-267965-84sotgds	51	26	musculus	musculus	NN
cord-267965-84sotgds	51	27	)	)	-RRB-
cord-267965-84sotgds	51	28	provides	provide	VBZ
cord-267965-84sotgds	51	29	the	the	DT
cord-267965-84sotgds	51	30	most	most	RBS
cord-267965-84sotgds	51	31	robust	robust	JJ
cord-267965-84sotgds	51	32	mammalian	mammalian	JJ
cord-267965-84sotgds	51	33	system	system	NN
cord-267965-84sotgds	51	34	for	for	IN
cord-267965-84sotgds	51	35	dissecting	dissect	VBG
cord-267965-84sotgds	51	36	genetic	genetic	JJ
cord-267965-84sotgds	51	37	regulation	regulation	NN
cord-267965-84sotgds	51	38	of	of	IN
cord-267965-84sotgds	51	39	immune	immune	JJ
cord-267965-84sotgds	51	40	responses	response	NNS
cord-267965-84sotgds	51	41	in	in	IN
cord-267965-84sotgds	51	42	human	human	NN
cord-267965-84sotgds	51	43	-	-	HYPH
cord-267965-84sotgds	51	44	relevant	relevant	JJ
cord-267965-84sotgds	51	45	diseases	disease	NNS
cord-267965-84sotgds	51	46	.	.	.
cord-267965-84sotgds	52	1	Mice	mouse	NNS
cord-267965-84sotgds	52	2	are	be	VBP
cord-267965-84sotgds	52	3	relatively	relatively	RB
cord-267965-84sotgds	52	4	inexpensive	inexpensive	JJ
cord-267965-84sotgds	52	5	,	,	,
cord-267965-84sotgds	52	6	can	can	MD
cord-267965-84sotgds	52	7	be	be	VB
cord-267965-84sotgds	52	8	easily	easily	RB
cord-267965-84sotgds	52	9	controlled	control	VBN
cord-267965-84sotgds	52	10	in	in	IN
cord-267965-84sotgds	52	11	diet	diet	NN
cord-267965-84sotgds	52	12	and	and	CC
cord-267965-84sotgds	52	13	environment	environment	NN
cord-267965-84sotgds	52	14	,	,	,
cord-267965-84sotgds	52	15	and	and	CC
cord-267965-84sotgds	52	16	reproduce	reproduce	VB
cord-267965-84sotgds	52	17	quickly	quickly	RB
cord-267965-84sotgds	52	18	.	.	.
cord-267965-84sotgds	53	1	A	a	DT
cord-267965-84sotgds	53	2	wide	wide	JJ
cord-267965-84sotgds	53	3	variety	variety	NN
cord-267965-84sotgds	53	4	of	of	IN
cord-267965-84sotgds	53	5	well	well	RB
cord-267965-84sotgds	53	6	-	-	HYPH
cord-267965-84sotgds	53	7	characterized	characterize	VBN
cord-267965-84sotgds	53	8	mouse	mouse	NN
cord-267965-84sotgds	53	9	immunological	immunological	JJ
cord-267965-84sotgds	53	10	reagents	reagent	NNS
cord-267965-84sotgds	53	11	are	be	VBP
cord-267965-84sotgds	53	12	available	available	JJ
cord-267965-84sotgds	53	13	,	,	,
cord-267965-84sotgds	53	14	as	as	RB
cord-267965-84sotgds	53	15	well	well	RB
cord-267965-84sotgds	53	16	as	as	IN
cord-267965-84sotgds	53	17	genetic	genetic	JJ
cord-267965-84sotgds	53	18	tools	tool	NNS
cord-267965-84sotgds	53	19	such	such	JJ
cord-267965-84sotgds	53	20	as	as	IN
cord-267965-84sotgds	53	21	reproducible	reproducible	JJ
cord-267965-84sotgds	53	22	inbred	inbred	JJ
cord-267965-84sotgds	53	23	strains	strain	NNS
cord-267965-84sotgds	53	24	,	,	,
cord-267965-84sotgds	53	25	gene	gene	NN
cord-267965-84sotgds	53	26	-	-	HYPH
cord-267965-84sotgds	53	27	specific	specific	JJ
cord-267965-84sotgds	53	28	knockouts	knockout	NNS
cord-267965-84sotgds	53	29	,	,	,
cord-267965-84sotgds	53	30	genome	genome	NN
cord-267965-84sotgds	53	31	-	-	HYPH
cord-267965-84sotgds	53	32	wide	wide	JJ
cord-267965-84sotgds	53	33	mutagenesis	mutagenesis	NN
cord-267965-84sotgds	53	34	strategies	strategy	NNS
cord-267965-84sotgds	53	35	(	(	-LRB-
cord-267965-84sotgds	53	36	e.g.	e.g.	RB
cord-267965-84sotgds	53	37	,	,	,
cord-267965-84sotgds	53	38	N	n	CD
cord-267965-84sotgds	53	39	-	-	HYPH
cord-267965-84sotgds	53	40	ethyl	ethyl	NNP
cord-267965-84sotgds	53	41	-	-	HYPH
cord-267965-84sotgds	53	42	N	N	NNP
cord-267965-84sotgds	53	43	-	-	HYPH
cord-267965-84sotgds	53	44	nitrosourea	nitrosourea	NNP
cord-267965-84sotgds	53	45	[	[	-LRB-
cord-267965-84sotgds	53	46	ENU	ENU	NNP
cord-267965-84sotgds	53	47	]	]	-RRB-
cord-267965-84sotgds	53	48	and	and	CC
cord-267965-84sotgds	53	49	CRISPR	CRISPR	NNP
cord-267965-84sotgds	53	50	/	/	SYM
cord-267965-84sotgds	53	51	Cas9	Cas9	NNP
cord-267965-84sotgds	53	52	)	)	-RRB-
cord-267965-84sotgds	53	53	,	,	,
cord-267965-84sotgds	53	54	and	and	CC
cord-267965-84sotgds	53	55	transgenic	transgenic	JJ
cord-267965-84sotgds	53	56	technologies	technology	NNS
cord-267965-84sotgds	53	57	.	.	.
cord-267965-84sotgds	54	1	These	these	DT
cord-267965-84sotgds	54	2	systems	system	NNS
cord-267965-84sotgds	54	3	facilitate	facilitate	VBP
cord-267965-84sotgds	54	4	the	the	DT
cord-267965-84sotgds	54	5	identification	identification	NN
cord-267965-84sotgds	54	6	and	and	CC
cord-267965-84sotgds	54	7	mechanistic	mechanistic	JJ
cord-267965-84sotgds	54	8	characterization	characterization	NN
cord-267965-84sotgds	54	9	of	of	IN
cord-267965-84sotgds	54	10	specific	specific	JJ
cord-267965-84sotgds	54	11	host	host	NN
cord-267965-84sotgds	54	12	genes	gene	NNS
cord-267965-84sotgds	54	13	that	that	WDT
cord-267965-84sotgds	54	14	affect	affect	VBP
cord-267965-84sotgds	54	15	disease	disease	NN
cord-267965-84sotgds	54	16	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	54	17	and/or	and/or	CC
cord-267965-84sotgds	54	18	immunity	immunity	NN
cord-267965-84sotgds	55	1	(	(	-LRB-
cord-267965-84sotgds	55	2	Pelletier	Pelletier	NNP
cord-267965-84sotgds	55	3	et	et	NNP
cord-267965-84sotgds	55	4	al	al	NNP
cord-267965-84sotgds	55	5	.	.	.
cord-267965-84sotgds	56	1	,	,	,
cord-267965-84sotgds	56	2	2015	2015	CD
cord-267965-84sotgds	56	3	;	;	:
cord-267965-84sotgds	56	4	Takaki	Takaki	NNP
cord-267965-84sotgds	56	5	et	et	NNP
cord-267965-84sotgds	56	6	al	al	NNP
cord-267965-84sotgds	56	7	.	.	NNP
cord-267965-84sotgds	56	8	,	,	,
cord-267965-84sotgds	56	9	2017	2017	CD
cord-267965-84sotgds	56	10	)	)	-RRB-
cord-267965-84sotgds	56	11	.	.	.
cord-267965-84sotgds	57	1	Though	though	IN
cord-267965-84sotgds	57	2	over	over	IN
cord-267965-84sotgds	57	3	450	450	CD
cord-267965-84sotgds	57	4	commercially	commercially	RB
cord-267965-84sotgds	57	5	available	available	JJ
cord-267965-84sotgds	57	6	inbred	inbred	JJ
cord-267965-84sotgds	57	7	mouse	mouse	NN
cord-267965-84sotgds	57	8	strains	strain	NNS
cord-267965-84sotgds	57	9	and	and	CC
cord-267965-84sotgds	57	10	outbred	outbred	JJ
cord-267965-84sotgds	57	11	stocks	stock	NNS
cord-267965-84sotgds	57	12	are	be	VBP
cord-267965-84sotgds	57	13	available	available	JJ
cord-267965-84sotgds	57	14	(	(	-LRB-
cord-267965-84sotgds	57	15	Beck	Beck	NNP
cord-267965-84sotgds	57	16	et	et	NNP
cord-267965-84sotgds	57	17	al	al	NNP
cord-267965-84sotgds	57	18	.	.	NNP
cord-267965-84sotgds	57	19	,	,	,
cord-267965-84sotgds	57	20	2000	2000	CD
cord-267965-84sotgds	57	21	)	)	-RRB-
cord-267965-84sotgds	57	22	,	,	,
cord-267965-84sotgds	57	23	the	the	DT
cord-267965-84sotgds	57	24	majority	majority	NN
cord-267965-84sotgds	57	25	of	of	IN
cord-267965-84sotgds	57	26	research	research	NN
cord-267965-84sotgds	57	27	in	in	IN
cord-267965-84sotgds	57	28	infectious	infectious	JJ
cord-267965-84sotgds	57	29	disease	disease	NN
cord-267965-84sotgds	57	30	and	and	CC
cord-267965-84sotgds	57	31	immunology	immunology	NN
cord-267965-84sotgds	57	32	is	be	VBZ
cord-267965-84sotgds	57	33	conducted	conduct	VBN
cord-267965-84sotgds	57	34	in	in	IN
cord-267965-84sotgds	57	35	a	a	DT
cord-267965-84sotgds	57	36	limited	limited	JJ
cord-267965-84sotgds	57	37	set	set	NN
cord-267965-84sotgds	57	38	of	of	IN
cord-267965-84sotgds	57	39	strains	strain	NNS
cord-267965-84sotgds	57	40	.	.	.
cord-267965-84sotgds	58	1	One	one	CD
cord-267965-84sotgds	58	2	of	of	IN
cord-267965-84sotgds	58	3	the	the	DT
cord-267965-84sotgds	58	4	major	major	JJ
cord-267965-84sotgds	58	5	reasons	reason	NNS
cord-267965-84sotgds	58	6	for	for	IN
cord-267965-84sotgds	58	7	the	the	DT
cord-267965-84sotgds	58	8	focus	focus	NN
cord-267965-84sotgds	58	9	on	on	IN
cord-267965-84sotgds	58	10	specific	specific	JJ
cord-267965-84sotgds	58	11	strains	strain	NNS
cord-267965-84sotgds	58	12	is	be	VBZ
cord-267965-84sotgds	58	13	the	the	DT
cord-267965-84sotgds	58	14	need	need	NN
cord-267965-84sotgds	58	15	to	to	TO
cord-267965-84sotgds	58	16	control	control	VB
cord-267965-84sotgds	58	17	for	for	IN
cord-267965-84sotgds	58	18	genetic	genetic	JJ
cord-267965-84sotgds	58	19	background	background	NN
cord-267965-84sotgds	58	20	when	when	WRB
cord-267965-84sotgds	58	21	analyzing	analyze	VBG
cord-267965-84sotgds	58	22	gene	gene	NN
cord-267965-84sotgds	58	23	-	-	HYPH
cord-267965-84sotgds	58	24	specific	specific	JJ
cord-267965-84sotgds	58	25	knockouts	knockout	NNS
cord-267965-84sotgds	58	26	or	or	CC
cord-267965-84sotgds	58	27	performing	perform	VBG
cord-267965-84sotgds	58	28	largescale	largescale	JJ
cord-267965-84sotgds	58	29	mutagenesis	mutagenesis	NN
cord-267965-84sotgds	58	30	screens	screen	NNS
cord-267965-84sotgds	58	31	.	.	.
cord-267965-84sotgds	59	1	Large	large	JJ
cord-267965-84sotgds	59	2	-	-	HYPH
cord-267965-84sotgds	59	3	scale	scale	NN
cord-267965-84sotgds	59	4	initiatives	initiative	NNS
cord-267965-84sotgds	59	5	such	such	JJ
cord-267965-84sotgds	59	6	as	as	IN
cord-267965-84sotgds	59	7	the	the	DT
cord-267965-84sotgds	59	8	International	International	NNP
cord-267965-84sotgds	59	9	Mouse	Mouse	NNP
cord-267965-84sotgds	59	10	Phenotyping	Phenotyping	NNP
cord-267965-84sotgds	59	11	Consortium	Consortium	NNP
cord-267965-84sotgds	59	12	(	(	-LRB-
cord-267965-84sotgds	59	13	IMPC	IMPC	NNP
cord-267965-84sotgds	59	14	)	)	-RRB-
cord-267965-84sotgds	59	15	depend	depend	VBP
cord-267965-84sotgds	59	16	upon	upon	IN
cord-267965-84sotgds	59	17	the	the	DT
cord-267965-84sotgds	59	18	ability	ability	NN
cord-267965-84sotgds	59	19	to	to	TO
cord-267965-84sotgds	59	20	control	control	VB
cord-267965-84sotgds	59	21	background	background	NN
cord-267965-84sotgds	59	22	strain	strain	NN
cord-267965-84sotgds	59	23	to	to	TO
cord-267965-84sotgds	59	24	analyze	analyze	VB
cord-267965-84sotgds	59	25	the	the	DT
cord-267965-84sotgds	59	26	impact	impact	NN
cord-267965-84sotgds	59	27	of	of	IN
cord-267965-84sotgds	59	28	specific	specific	JJ
cord-267965-84sotgds	59	29	gene	gene	NN
cord-267965-84sotgds	59	30	deletions	deletion	NNS
cord-267965-84sotgds	59	31	or	or	CC
cord-267965-84sotgds	59	32	mutations	mutation	NNS
cord-267965-84sotgds	59	33	on	on	IN
cord-267965-84sotgds	59	34	a	a	DT
cord-267965-84sotgds	59	35	wide	wide	JJ
cord-267965-84sotgds	59	36	range	range	NN
cord-267965-84sotgds	59	37	of	of	IN
cord-267965-84sotgds	59	38	developmental	developmental	JJ
cord-267965-84sotgds	59	39	and	and	CC
cord-267965-84sotgds	59	40	immune	immune	JJ
cord-267965-84sotgds	59	41	phenotypes	phenotype	NNS
cord-267965-84sotgds	59	42	(	(	-LRB-
cord-267965-84sotgds	59	43	Muñ	Muñ	NNP
cord-267965-84sotgds	59	44	oz	oz	NNP
cord-267965-84sotgds	59	45	-	-	HYPH
cord-267965-84sotgds	59	46	Fuentes	Fuentes	NNPS
cord-267965-84sotgds	59	47	et	et	NNP
cord-267965-84sotgds	59	48	al	al	NNP
cord-267965-84sotgds	59	49	.	.	NNP
cord-267965-84sotgds	59	50	,	,	,
cord-267965-84sotgds	59	51	2018	2018	CD
cord-267965-84sotgds	59	52	)	)	-RRB-
cord-267965-84sotgds	59	53	,	,	,
cord-267965-84sotgds	59	54	and	and	CC
cord-267965-84sotgds	59	55	have	have	VBP
cord-267965-84sotgds	59	56	thus	thus	RB
cord-267965-84sotgds	59	57	generated	generate	VBN
cord-267965-84sotgds	59	58	these	these	DT
cord-267965-84sotgds	59	59	mutants	mutant	NNS
cord-267965-84sotgds	59	60	on	on	IN
cord-267965-84sotgds	59	61	common	common	JJ
cord-267965-84sotgds	59	62	backgrounds	background	NNS
cord-267965-84sotgds	59	63	using	use	VBG
cord-267965-84sotgds	59	64	largely	largely	RB
cord-267965-84sotgds	59	65	identical	identical	JJ
cord-267965-84sotgds	59	66	procedures	procedure	NNS
cord-267965-84sotgds	59	67	.	.	.
cord-267965-84sotgds	60	1	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	60	2	is	be	VBZ
cord-267965-84sotgds	60	3	the	the	DT
cord-267965-84sotgds	60	4	most	most	RBS
cord-267965-84sotgds	60	5	commonly	commonly	RB
cord-267965-84sotgds	60	6	used	use	VBN
cord-267965-84sotgds	60	7	inbred	inbred	JJ
cord-267965-84sotgds	60	8	mouse	mouse	NN
cord-267965-84sotgds	60	9	strain	strain	NN
cord-267965-84sotgds	60	10	;	;	:
cord-267965-84sotgds	60	11	it	-PRON-	PRP
cord-267965-84sotgds	60	12	is	be	VBZ
cord-267965-84sotgds	60	13	the	the	DT
cord-267965-84sotgds	60	14	source	source	NN
cord-267965-84sotgds	60	15	of	of	IN
cord-267965-84sotgds	60	16	the	the	DT
cord-267965-84sotgds	60	17	mouse	mouse	NN
cord-267965-84sotgds	60	18	reference	reference	NN
cord-267965-84sotgds	60	19	genome	genome	NN
cord-267965-84sotgds	60	20	and	and	CC
cord-267965-84sotgds	60	21	the	the	DT
cord-267965-84sotgds	60	22	genetic	genetic	JJ
cord-267965-84sotgds	60	23	background	background	NN
cord-267965-84sotgds	60	24	for	for	IN
cord-267965-84sotgds	60	25	the	the	DT
cord-267965-84sotgds	60	26	majority	majority	NN
cord-267965-84sotgds	60	27	of	of	IN
cord-267965-84sotgds	60	28	knockout	knockout	NN
cord-267965-84sotgds	60	29	mice	mouse	NNS
cord-267965-84sotgds	60	30	.	.	.
cord-267965-84sotgds	61	1	Other	other	JJ
cord-267965-84sotgds	61	2	strains	strain	NNS
cord-267965-84sotgds	61	3	,	,	,
cord-267965-84sotgds	61	4	such	such	JJ
cord-267965-84sotgds	61	5	as	as	IN
cord-267965-84sotgds	61	6	the	the	DT
cord-267965-84sotgds	61	7	BALB	BALB	NNP
cord-267965-84sotgds	61	8	/	/	SYM
cord-267965-84sotgds	61	9	c	c	NN
cord-267965-84sotgds	61	10	substrains	substrain	NNS
cord-267965-84sotgds	61	11	,	,	,
cord-267965-84sotgds	61	12	also	also	RB
cord-267965-84sotgds	61	13	have	have	VBP
cord-267965-84sotgds	61	14	a	a	DT
cord-267965-84sotgds	61	15	rich	rich	JJ
cord-267965-84sotgds	61	16	history	history	NN
cord-267965-84sotgds	61	17	of	of	IN
cord-267965-84sotgds	61	18	use	use	NN
cord-267965-84sotgds	61	19	in	in	IN
cord-267965-84sotgds	61	20	immunology	immunology	NN
cord-267965-84sotgds	61	21	and	and	CC
cord-267965-84sotgds	61	22	infectious	infectious	JJ
cord-267965-84sotgds	61	23	disease	disease	NN
cord-267965-84sotgds	61	24	research	research	NN
cord-267965-84sotgds	62	1	(	(	-LRB-
cord-267965-84sotgds	62	2	Watanabe	Watanabe	NNP
cord-267965-84sotgds	62	3	et	et	NNP
cord-267965-84sotgds	62	4	al	al	NNP
cord-267965-84sotgds	62	5	.	.	NNP
cord-267965-84sotgds	62	6	,	,	,
cord-267965-84sotgds	62	7	2004	2004	CD
cord-267965-84sotgds	62	8	)	)	-RRB-
cord-267965-84sotgds	62	9	.	.	.
cord-267965-84sotgds	63	1	While	while	IN
cord-267965-84sotgds	63	2	the	the	DT
cord-267965-84sotgds	63	3	ongoing	ongoing	JJ
cord-267965-84sotgds	63	4	use	use	NN
cord-267965-84sotgds	63	5	of	of	IN
cord-267965-84sotgds	63	6	such	such	JJ
cord-267965-84sotgds	63	7	strains	strain	NNS
cord-267965-84sotgds	63	8	is	be	VBZ
cord-267965-84sotgds	63	9	driven	drive	VBN
cord-267965-84sotgds	63	10	by	by	IN
cord-267965-84sotgds	63	11	the	the	DT
cord-267965-84sotgds	63	12	need	need	NN
cord-267965-84sotgds	63	13	to	to	TO
cord-267965-84sotgds	63	14	compare	compare	VB
cord-267965-84sotgds	63	15	results	result	NNS
cord-267965-84sotgds	63	16	across	across	IN
cord-267965-84sotgds	63	17	studies	study	NNS
cord-267965-84sotgds	63	18	,	,	,
cord-267965-84sotgds	63	19	it	-PRON-	PRP
cord-267965-84sotgds	63	20	is	be	VBZ
cord-267965-84sotgds	63	21	important	important	JJ
cord-267965-84sotgds	63	22	to	to	TO
cord-267965-84sotgds	63	23	note	note	VB
cord-267965-84sotgds	63	24	that	that	IN
cord-267965-84sotgds	63	25	every	every	DT
cord-267965-84sotgds	63	26	inbred	inbred	JJ
cord-267965-84sotgds	63	27	strain	strain	NN
cord-267965-84sotgds	63	28	has	have	VBZ
cord-267965-84sotgds	63	29	a	a	DT
cord-267965-84sotgds	63	30	unique	unique	JJ
cord-267965-84sotgds	63	31	set	set	NN
cord-267965-84sotgds	63	32	of	of	IN
cord-267965-84sotgds	63	33	genetic	genetic	JJ
cord-267965-84sotgds	63	34	features	feature	NNS
cord-267965-84sotgds	63	35	,	,	,
cord-267965-84sotgds	63	36	and	and	CC
cord-267965-84sotgds	63	37	thus	thus	RB
cord-267965-84sotgds	63	38	no	no	DT
cord-267965-84sotgds	63	39	one	one	CD
cord-267965-84sotgds	63	40	strain	strain	NN
cord-267965-84sotgds	63	41	is	be	VBZ
cord-267965-84sotgds	63	42	representative	representative	JJ
cord-267965-84sotgds	63	43	of	of	IN
cord-267965-84sotgds	63	44	all	all	DT
cord-267965-84sotgds	63	45	mice	mouse	NNS
cord-267965-84sotgds	63	46	,	,	,
cord-267965-84sotgds	63	47	let	let	VB
cord-267965-84sotgds	63	48	alone	alone	RB
cord-267965-84sotgds	63	49	of	of	IN
cord-267965-84sotgds	63	50	a	a	DT
cord-267965-84sotgds	63	51	genetically	genetically	RB
cord-267965-84sotgds	63	52	complex	complex	JJ
cord-267965-84sotgds	63	53	population	population	NN
cord-267965-84sotgds	63	54	such	such	JJ
cord-267965-84sotgds	63	55	as	as	IN
cord-267965-84sotgds	63	56	humans	human	NNS
cord-267965-84sotgds	63	57	.	.	.
cord-267965-84sotgds	64	1	Although	although	IN
cord-267965-84sotgds	64	2	genetically	genetically	RB
cord-267965-84sotgds	64	3	modified	modify	VBN
cord-267965-84sotgds	64	4	mice	mouse	NNS
cord-267965-84sotgds	64	5	have	have	VBP
cord-267965-84sotgds	64	6	been	be	VBN
cord-267965-84sotgds	64	7	an	an	DT
cord-267965-84sotgds	64	8	essential	essential	JJ
cord-267965-84sotgds	64	9	resource	resource	NN
cord-267965-84sotgds	64	10	for	for	IN
cord-267965-84sotgds	64	11	gene	gene	NN
cord-267965-84sotgds	64	12	discovery	discovery	NN
cord-267965-84sotgds	64	13	and	and	CC
cord-267965-84sotgds	64	14	mechanistic	mechanistic	JJ
cord-267965-84sotgds	64	15	analysis	analysis	NN
cord-267965-84sotgds	64	16	,	,	,
cord-267965-84sotgds	64	17	there	there	EX
cord-267965-84sotgds	64	18	has	have	VBZ
cord-267965-84sotgds	64	19	been	be	VBN
cord-267965-84sotgds	64	20	a	a	DT
cord-267965-84sotgds	64	21	growing	grow	VBG
cord-267965-84sotgds	64	22	acknowledgment	acknowledgment	NN
cord-267965-84sotgds	64	23	in	in	IN
cord-267965-84sotgds	64	24	the	the	DT
cord-267965-84sotgds	64	25	field	field	NN
cord-267965-84sotgds	64	26	that	that	WDT
cord-267965-84sotgds	64	27	knockout	knockout	NN
cord-267965-84sotgds	64	28	approaches	approach	NNS
cord-267965-84sotgds	64	29	have	have	VBP
cord-267965-84sotgds	64	30	limitations	limitation	NNS
cord-267965-84sotgds	64	31	.	.	.
cord-267965-84sotgds	65	1	Approximately	approximately	RB
cord-267965-84sotgds	65	2	15	15	CD
cord-267965-84sotgds	65	3	%	%	NN
cord-267965-84sotgds	65	4	of	of	IN
cord-267965-84sotgds	65	5	genes	gene	NNS
cord-267965-84sotgds	65	6	can	can	MD
cord-267965-84sotgds	65	7	not	not	RB
cord-267965-84sotgds	65	8	be	be	VB
cord-267965-84sotgds	65	9	knocked	knock	VBN
cord-267965-84sotgds	65	10	out	out	RP
cord-267965-84sotgds	65	11	because	because	IN
cord-267965-84sotgds	65	12	they	-PRON-	PRP
cord-267965-84sotgds	65	13	are	be	VBP
cord-267965-84sotgds	65	14	developmentally	developmentally	RB
cord-267965-84sotgds	65	15	essential	essential	JJ
cord-267965-84sotgds	65	16	(	(	-LRB-
cord-267965-84sotgds	65	17	NIH	NIH	NNP
cord-267965-84sotgds	65	18	,	,	,
cord-267965-84sotgds	65	19	2015	2015	CD
cord-267965-84sotgds	65	20	)	)	-RRB-
cord-267965-84sotgds	65	21	.	.	.
cord-267965-84sotgds	66	1	Similarly	similarly	RB
cord-267965-84sotgds	66	2	,	,	,
cord-267965-84sotgds	66	3	other	other	JJ
cord-267965-84sotgds	66	4	knockouts	knockout	NNS
cord-267965-84sotgds	66	5	have	have	VBP
cord-267965-84sotgds	66	6	no	no	DT
cord-267965-84sotgds	66	7	observable	observable	JJ
cord-267965-84sotgds	66	8	phenotype	phenotype	NN
cord-267965-84sotgds	66	9	,	,	,
cord-267965-84sotgds	66	10	due	due	IN
cord-267965-84sotgds	66	11	to	to	IN
cord-267965-84sotgds	66	12	genetic	genetic	JJ
cord-267965-84sotgds	66	13	redundancy	redundancy	NN
cord-267965-84sotgds	66	14	and/or	and/or	CC
cord-267965-84sotgds	66	15	lack	lack	NN
cord-267965-84sotgds	66	16	of	of	IN
cord-267965-84sotgds	66	17	robustness	robustness	NN
cord-267965-84sotgds	66	18	in	in	IN
cord-267965-84sotgds	66	19	the	the	DT
cord-267965-84sotgds	66	20	phenotyping	phenotyping	NN
cord-267965-84sotgds	66	21	pipeline	pipeline	NN
cord-267965-84sotgds	66	22	(	(	-LRB-
cord-267965-84sotgds	66	23	Barbaric	barbaric	JJ
cord-267965-84sotgds	66	24	et	et	FW
cord-267965-84sotgds	66	25	al	al	NNP
cord-267965-84sotgds	66	26	.	.	NNP
cord-267965-84sotgds	66	27	,	,	,
cord-267965-84sotgds	66	28	2007	2007	CD
cord-267965-84sotgds	66	29	)	)	-RRB-
cord-267965-84sotgds	66	30	.	.	.
cord-267965-84sotgds	67	1	In	in	IN
cord-267965-84sotgds	67	2	other	other	JJ
cord-267965-84sotgds	67	3	cases	case	NNS
cord-267965-84sotgds	67	4	,	,	,
cord-267965-84sotgds	67	5	knockouts	knockout	NNS
cord-267965-84sotgds	67	6	have	have	VBP
cord-267965-84sotgds	67	7	disparate	disparate	JJ
cord-267965-84sotgds	67	8	phenotypes	phenotype	NNS
cord-267965-84sotgds	67	9	on	on	IN
cord-267965-84sotgds	67	10	different	different	JJ
cord-267965-84sotgds	67	11	genetic	genetic	JJ
cord-267965-84sotgds	67	12	backgrounds	background	NNS
cord-267965-84sotgds	67	13	due	due	JJ
cord-267965-84sotgds	67	14	to	to	IN
cord-267965-84sotgds	67	15	gene	gene	NN
cord-267965-84sotgds	67	16	-	-	HYPH
cord-267965-84sotgds	67	17	gene	gene	NN
cord-267965-84sotgds	67	18	interactions	interaction	NNS
cord-267965-84sotgds	67	19	(	(	-LRB-
cord-267965-84sotgds	67	20	Doetschman	Doetschman	NNP
cord-267965-84sotgds	67	21	,	,	,
cord-267965-84sotgds	67	22	2009	2009	CD
cord-267965-84sotgds	67	23	)	)	-RRB-
cord-267965-84sotgds	67	24	.	.	.
cord-267965-84sotgds	68	1	Furthermore	furthermore	RB
cord-267965-84sotgds	68	2	,	,	,
cord-267965-84sotgds	68	3	gene	gene	NN
cord-267965-84sotgds	68	4	knockouts	knockout	NNS
cord-267965-84sotgds	68	5	result	result	VBP
cord-267965-84sotgds	68	6	in	in	IN
cord-267965-84sotgds	68	7	null	null	JJ
cord-267965-84sotgds	68	8	alleles	allele	NNS
cord-267965-84sotgds	68	9	(	(	-LRB-
cord-267965-84sotgds	68	10	complete	complete	JJ
cord-267965-84sotgds	68	11	loss	loss	NN
cord-267965-84sotgds	68	12	of	of	IN
cord-267965-84sotgds	68	13	gene	gene	NN
cord-267965-84sotgds	68	14	function	function	NN
cord-267965-84sotgds	68	15	)	)	-RRB-
cord-267965-84sotgds	68	16	,	,	,
cord-267965-84sotgds	68	17	whereas	whereas	IN
cord-267965-84sotgds	68	18	naturally	naturally	RB
cord-267965-84sotgds	68	19	occurring	occur	VBG
cord-267965-84sotgds	68	20	genetic	genetic	JJ
cord-267965-84sotgds	68	21	variants	variant	NNS
cord-267965-84sotgds	68	22	are	be	VBP
cord-267965-84sotgds	68	23	most	most	RBS
cord-267965-84sotgds	68	24	likely	likely	JJ
cord-267965-84sotgds	68	25	to	to	TO
cord-267965-84sotgds	68	26	be	be	VB
cord-267965-84sotgds	68	27	hypomorphic	hypomorphic	JJ
cord-267965-84sotgds	68	28	or	or	CC
cord-267965-84sotgds	68	29	hypermorphic	hypermorphic	JJ
cord-267965-84sotgds	68	30	alleles	allele	NNS
cord-267965-84sotgds	68	31	(	(	-LRB-
cord-267965-84sotgds	68	32	partial	partial	JJ
cord-267965-84sotgds	68	33	loss	loss	NN
cord-267965-84sotgds	68	34	or	or	CC
cord-267965-84sotgds	68	35	gain	gain	NN
cord-267965-84sotgds	68	36	of	of	IN
cord-267965-84sotgds	68	37	gene	gene	NN
cord-267965-84sotgds	68	38	function	function	NN
cord-267965-84sotgds	68	39	;	;	:
cord-267965-84sotgds	68	40	alterations	alteration	NNS
cord-267965-84sotgds	68	41	in	in	IN
cord-267965-84sotgds	68	42	timing	timing	NN
cord-267965-84sotgds	68	43	and	and	CC
cord-267965-84sotgds	68	44	magnitude	magnitude	NN
cord-267965-84sotgds	68	45	of	of	IN
cord-267965-84sotgds	68	46	expression	expression	NN
cord-267965-84sotgds	68	47	)	)	-RRB-
cord-267965-84sotgds	68	48	.	.	.
cord-267965-84sotgds	69	1	Lastly	lastly	RB
cord-267965-84sotgds	69	2	,	,	,
cord-267965-84sotgds	69	3	while	while	IN
cord-267965-84sotgds	69	4	single	single	JJ
cord-267965-84sotgds	69	5	-	-	HYPH
cord-267965-84sotgds	69	6	gene	gene	NN
cord-267965-84sotgds	69	7	approaches	approach	NNS
cord-267965-84sotgds	69	8	are	be	VBP
cord-267965-84sotgds	69	9	straightforward	straightforward	JJ
cord-267965-84sotgds	69	10	,	,	,
cord-267965-84sotgds	69	11	they	-PRON-	PRP
cord-267965-84sotgds	69	12	are	be	VBP
cord-267965-84sotgds	69	13	isolated	isolate	VBN
cord-267965-84sotgds	69	14	systems	system	NNS
cord-267965-84sotgds	69	15	that	that	WDT
cord-267965-84sotgds	69	16	do	do	VBP
cord-267965-84sotgds	69	17	not	not	RB
cord-267965-84sotgds	69	18	model	model	VB
cord-267965-84sotgds	69	19	the	the	DT
cord-267965-84sotgds	69	20	simultaneous	simultaneous	JJ
cord-267965-84sotgds	69	21	contribution	contribution	NN
cord-267965-84sotgds	69	22	of	of	IN
cord-267965-84sotgds	69	23	variants	variant	NNS
cord-267965-84sotgds	69	24	in	in	IN
cord-267965-84sotgds	69	25	multiple	multiple	JJ
cord-267965-84sotgds	69	26	pathways	pathway	NNS
cord-267965-84sotgds	69	27	,	,	,
cord-267965-84sotgds	69	28	as	as	IN
cord-267965-84sotgds	69	29	would	would	MD
cord-267965-84sotgds	69	30	most	most	RBS
cord-267965-84sotgds	69	31	likely	likely	RB
cord-267965-84sotgds	69	32	be	be	VB
cord-267965-84sotgds	69	33	observed	observe	VBN
cord-267965-84sotgds	69	34	in	in	IN
cord-267965-84sotgds	69	35	a	a	DT
cord-267965-84sotgds	69	36	natural	natural	JJ
cord-267965-84sotgds	69	37	system	system	NN
cord-267965-84sotgds	69	38	.	.	.
cord-267965-84sotgds	70	1	Thus	thus	RB
cord-267965-84sotgds	70	2	,	,	,
cord-267965-84sotgds	70	3	to	to	TO
cord-267965-84sotgds	70	4	better	well	JJR
cord-267965-84sotgds	70	5	model	model	VB
cord-267965-84sotgds	70	6	and	and	CC
cord-267965-84sotgds	70	7	understand	understand	VB
cord-267965-84sotgds	70	8	the	the	DT
cord-267965-84sotgds	70	9	role	role	NN
cord-267965-84sotgds	70	10	of	of	IN
cord-267965-84sotgds	70	11	genes	gene	NNS
cord-267965-84sotgds	70	12	in	in	IN
cord-267965-84sotgds	70	13	complex	complex	JJ
cord-267965-84sotgds	70	14	phenotypes	phenotype	NNS
cord-267965-84sotgds	70	15	such	such	JJ
cord-267965-84sotgds	70	16	as	as	IN
cord-267965-84sotgds	70	17	immunity	immunity	NN
cord-267965-84sotgds	70	18	and	and	CC
cord-267965-84sotgds	70	19	infectious	infectious	JJ
cord-267965-84sotgds	70	20	disease	disease	NN
cord-267965-84sotgds	70	21	,	,	,
cord-267965-84sotgds	70	22	it	-PRON-	PRP
cord-267965-84sotgds	70	23	is	be	VBZ
cord-267965-84sotgds	70	24	pertinent	pertinent	JJ
cord-267965-84sotgds	70	25	to	to	TO
cord-267965-84sotgds	70	26	consider	consider	VB
cord-267965-84sotgds	70	27	complex	complex	JJ
cord-267965-84sotgds	70	28	genetic	genetic	JJ
cord-267965-84sotgds	70	29	interactions	interaction	NNS
cord-267965-84sotgds	70	30	across	across	IN
cord-267965-84sotgds	70	31	diverse	diverse	JJ
cord-267965-84sotgds	70	32	genetic	genetic	JJ
cord-267965-84sotgds	70	33	backgrounds	background	NNS
cord-267965-84sotgds	70	34	.	.	.
cord-267965-84sotgds	71	1	In	in	IN
cord-267965-84sotgds	71	2	contrast	contrast	NN
cord-267965-84sotgds	71	3	to	to	IN
cord-267965-84sotgds	71	4	the	the	DT
cord-267965-84sotgds	71	5	approaches	approach	NNS
cord-267965-84sotgds	71	6	discussed	discuss	VBN
cord-267965-84sotgds	71	7	above	above	RB
cord-267965-84sotgds	71	8	,	,	,
cord-267965-84sotgds	71	9	researchers	researcher	NNS
cord-267965-84sotgds	71	10	have	have	VBP
cord-267965-84sotgds	71	11	also	also	RB
cord-267965-84sotgds	71	12	studied	study	VBN
cord-267965-84sotgds	71	13	the	the	DT
cord-267965-84sotgds	71	14	role	role	NN
cord-267965-84sotgds	71	15	of	of	IN
cord-267965-84sotgds	71	16	natural	natural	JJ
cord-267965-84sotgds	71	17	genetic	genetic	JJ
cord-267965-84sotgds	71	18	variants	variant	NNS
cord-267965-84sotgds	71	19	by	by	IN
cord-267965-84sotgds	71	20	leveraging	leverage	VBG
cord-267965-84sotgds	71	21	differential	differential	JJ
cord-267965-84sotgds	71	22	phenotypes	phenotype	NNS
cord-267965-84sotgds	71	23	across	across	IN
cord-267965-84sotgds	71	24	inbred	inbred	JJ
cord-267965-84sotgds	71	25	strains	strain	NNS
cord-267965-84sotgds	71	26	,	,	,
cord-267965-84sotgds	71	27	using	use	VBG
cord-267965-84sotgds	71	28	classical	classical	JJ
cord-267965-84sotgds	71	29	genetic	genetic	JJ
cord-267965-84sotgds	71	30	breeding	breeding	NN
cord-267965-84sotgds	71	31	strategies	strategy	NNS
cord-267965-84sotgds	71	32	to	to	TO
cord-267965-84sotgds	71	33	identify	identify	VB
cord-267965-84sotgds	71	34	pathogen	pathogen	NN
cord-267965-84sotgds	71	35	susceptibility	susceptibility	NN
cord-267965-84sotgds	71	36	genes	gene	NNS
cord-267965-84sotgds	71	37	such	such	JJ
cord-267965-84sotgds	71	38	as	as	IN
cord-267965-84sotgds	71	39	Oas1b	Oas1b	NNP
cord-267965-84sotgds	71	40	,	,	,
cord-267965-84sotgds	71	41	immune	immune	JJ
cord-267965-84sotgds	71	42	cell	cell	NN
cord-267965-84sotgds	71	43	activating	activate	VBG
cord-267965-84sotgds	71	44	receptor	receptor	NNP
cord-267965-84sotgds	71	45	Ly49H	Ly49H	NNP
cord-267965-84sotgds	71	46	,	,	,
cord-267965-84sotgds	71	47	and	and	CC
cord-267965-84sotgds	71	48	large	large	JJ
cord-267965-84sotgds	71	49	interferon	interferon	NN
cord-267965-84sotgds	71	50	-	-	HYPH
cord-267965-84sotgds	71	51	induced	induce	VBN
cord-267965-84sotgds	71	52	GTPase	GTPase	NNP
cord-267965-84sotgds	71	53	Mx1	mx1	JJ
cord-267965-84sotgds	71	54	(	(	-LRB-
cord-267965-84sotgds	71	55	Casanova	Casanova	NNP
cord-267965-84sotgds	71	56	et	et	NNP
cord-267965-84sotgds	71	57	al	al	NNP
cord-267965-84sotgds	71	58	.	.	NNP
cord-267965-84sotgds	71	59	,	,	,
cord-267965-84sotgds	71	60	2002	2002	CD
cord-267965-84sotgds	71	61	)	)	-RRB-
cord-267965-84sotgds	71	62	.	.	.
cord-267965-84sotgds	72	1	In	in	IN
cord-267965-84sotgds	72	2	contrast	contrast	NN
cord-267965-84sotgds	72	3	to	to	IN
cord-267965-84sotgds	72	4	mapping	mapping	NN
cord-267965-84sotgds	72	5	crosses	crosse	NNS
cord-267965-84sotgds	72	6	between	between	IN
cord-267965-84sotgds	72	7	stocks	stock	NNS
cord-267965-84sotgds	72	8	(	(	-LRB-
cord-267965-84sotgds	72	9	e.g.	e.g.	RB
cord-267965-84sotgds	72	10	,	,	,
cord-267965-84sotgds	72	11	F2	f2	NN
cord-267965-84sotgds	72	12	crosses	cross	VBZ
cord-267965-84sotgds	72	13	)	)	-RRB-
cord-267965-84sotgds	72	14	,	,	,
cord-267965-84sotgds	72	15	where	where	WRB
cord-267965-84sotgds	72	16	each	each	DT
cord-267965-84sotgds	72	17	mouse	mouse	NN
cord-267965-84sotgds	72	18	is	be	VBZ
cord-267965-84sotgds	72	19	unique	unique	JJ
cord-267965-84sotgds	72	20	and	and	CC
cord-267965-84sotgds	72	21	therefore	therefore	RB
cord-267965-84sotgds	72	22	ephemeral	ephemeral	JJ
cord-267965-84sotgds	72	23	,	,	,
cord-267965-84sotgds	72	24	GRPs	grp	NNS
cord-267965-84sotgds	72	25	serve	serve	VBP
cord-267965-84sotgds	72	26	as	as	IN
cord-267965-84sotgds	72	27	reproducible	reproducible	JJ
cord-267965-84sotgds	72	28	models	model	NNS
cord-267965-84sotgds	72	29	to	to	TO
cord-267965-84sotgds	72	30	study	study	VB
cord-267965-84sotgds	72	31	the	the	DT
cord-267965-84sotgds	72	32	role	role	NN
cord-267965-84sotgds	72	33	of	of	IN
cord-267965-84sotgds	72	34	genetic	genetic	JJ
cord-267965-84sotgds	72	35	diversity	diversity	NN
cord-267965-84sotgds	72	36	.	.	.
cord-267965-84sotgds	73	1	GRPs	grp	NNS
cord-267965-84sotgds	73	2	consist	consist	VBP
cord-267965-84sotgds	73	3	of	of	IN
cord-267965-84sotgds	73	4	anywhere	anywhere	RB
cord-267965-84sotgds	73	5	from	from	IN
cord-267965-84sotgds	73	6	a	a	DT
cord-267965-84sotgds	73	7	few	few	JJ
cord-267965-84sotgds	73	8	to	to	IN
cord-267965-84sotgds	73	9	hundreds	hundred	NNS
cord-267965-84sotgds	73	10	of	of	IN
cord-267965-84sotgds	73	11	inbred	inbred	JJ
cord-267965-84sotgds	73	12	lines	line	NNS
cord-267965-84sotgds	73	13	derived	derive	VBN
cord-267965-84sotgds	73	14	and	and	CC
cord-267965-84sotgds	73	15	split	split	VBD
cord-267965-84sotgds	73	16	from	from	IN
cord-267965-84sotgds	73	17	a	a	DT
cord-267965-84sotgds	73	18	common	common	JJ
cord-267965-84sotgds	73	19	ancestral	ancestral	JJ
cord-267965-84sotgds	73	20	population	population	NN
cord-267965-84sotgds	73	21	,	,	,
cord-267965-84sotgds	73	22	and	and	CC
cord-267965-84sotgds	73	23	each	each	DT
cord-267965-84sotgds	73	24	line	line	NN
cord-267965-84sotgds	73	25	has	have	VBZ
cord-267965-84sotgds	73	26	a	a	DT
cord-267965-84sotgds	73	27	fixed	fix	VBN
cord-267965-84sotgds	73	28	and	and	CC
cord-267965-84sotgds	73	29	known	know	VBN
cord-267965-84sotgds	73	30	genome	genome	NN
cord-267965-84sotgds	73	31	that	that	WDT
cord-267965-84sotgds	73	32	can	can	MD
cord-267965-84sotgds	73	33	be	be	VB
cord-267965-84sotgds	73	34	replicated	replicate	VBN
cord-267965-84sotgds	73	35	indefinitely	indefinitely	RB
cord-267965-84sotgds	73	36	.	.	.
cord-267965-84sotgds	74	1	The	the	DT
cord-267965-84sotgds	74	2	existence	existence	NN
cord-267965-84sotgds	74	3	of	of	IN
cord-267965-84sotgds	74	4	reproducible	reproducible	JJ
cord-267965-84sotgds	74	5	yet	yet	CC
cord-267965-84sotgds	74	6	genetically	genetically	RB
cord-267965-84sotgds	74	7	diverse	diverse	JJ
cord-267965-84sotgds	74	8	individual	individual	JJ
cord-267965-84sotgds	74	9	mouse	mouse	NN
cord-267965-84sotgds	74	10	strains	strain	NNS
cord-267965-84sotgds	74	11	facilitates	facilitate	VBZ
cord-267965-84sotgds	74	12	study	study	NN
cord-267965-84sotgds	74	13	designs	design	NNS
cord-267965-84sotgds	74	14	that	that	WDT
cord-267965-84sotgds	74	15	involve	involve	VBP
cord-267965-84sotgds	74	16	case	case	NN
cord-267965-84sotgds	74	17	versus	versus	IN
cord-267965-84sotgds	74	18	control	control	NN
cord-267965-84sotgds	74	19	,	,	,
cord-267965-84sotgds	74	20	genotype	genotype	NN
cord-267965-84sotgds	74	21	by	by	IN
cord-267965-84sotgds	74	22	environment	environment	NN
cord-267965-84sotgds	74	23	interactions	interaction	NNS
cord-267965-84sotgds	74	24	(	(	-LRB-
cord-267965-84sotgds	74	25	GxE	GxE	NNP
cord-267965-84sotgds	74	26	)	)	-RRB-
cord-267965-84sotgds	74	27	,	,	,
cord-267965-84sotgds	74	28	and	and	CC
cord-267965-84sotgds	74	29	phenotypic	phenotypic	JJ
cord-267965-84sotgds	74	30	penetrance	penetrance	NN
cord-267965-84sotgds	74	31	or	or	CC
cord-267965-84sotgds	74	32	threshold	threshold	NN
cord-267965-84sotgds	74	33	traits	trait	NNS
cord-267965-84sotgds	74	34	.	.	.
cord-267965-84sotgds	75	1	These	these	DT
cord-267965-84sotgds	75	2	populations	population	NNS
cord-267965-84sotgds	75	3	further	further	RB
cord-267965-84sotgds	75	4	facilitate	facilitate	VBP
cord-267965-84sotgds	75	5	the	the	DT
cord-267965-84sotgds	75	6	integration	integration	NN
cord-267965-84sotgds	75	7	of	of	IN
cord-267965-84sotgds	75	8	phenotypic	phenotypic	JJ
cord-267965-84sotgds	75	9	,	,	,
cord-267965-84sotgds	75	10	genotypic	genotypic	JJ
cord-267965-84sotgds	75	11	,	,	,
cord-267965-84sotgds	75	12	and	and	CC
cord-267965-84sotgds	75	13	molecular	molecular	JJ
cord-267965-84sotgds	75	14	data	datum	NNS
cord-267965-84sotgds	75	15	for	for	IN
cord-267965-84sotgds	75	16	systems	system	NNS
cord-267965-84sotgds	75	17	-	-	HYPH
cord-267965-84sotgds	75	18	level	level	NN
cord-267965-84sotgds	75	19	data	datum	NNS
cord-267965-84sotgds	75	20	analysis	analysis	NN
cord-267965-84sotgds	75	21	while	while	IN
cord-267965-84sotgds	75	22	also	also	RB
cord-267965-84sotgds	75	23	allowing	allow	VBG
cord-267965-84sotgds	75	24	retrospective	retrospective	JJ
cord-267965-84sotgds	75	25	integration	integration	NN
cord-267965-84sotgds	75	26	of	of	IN
cord-267965-84sotgds	75	27	new	new	JJ
cord-267965-84sotgds	75	28	layers	layer	NNS
cord-267965-84sotgds	75	29	of	of	IN
cord-267965-84sotgds	75	30	data	datum	NNS
cord-267965-84sotgds	75	31	.	.	.
cord-267965-84sotgds	76	1	The	the	DT
cord-267965-84sotgds	76	2	first	first	JJ
cord-267965-84sotgds	76	3	recombinant	recombinant	JJ
cord-267965-84sotgds	76	4	inbred	inbred	JJ
cord-267965-84sotgds	76	5	panel	panel	NN
cord-267965-84sotgds	76	6	,	,	,
cord-267965-84sotgds	76	7	the	the	DT
cord-267965-84sotgds	76	8	CXB	CXB	NNP
cord-267965-84sotgds	76	9	(	(	-LRB-
cord-267965-84sotgds	76	10	BALB	BALB	NNP
cord-267965-84sotgds	76	11	/	/	SYM
cord-267965-84sotgds	76	12	cJ	cj	NN
cord-267965-84sotgds	76	13	3	3	CD
cord-267965-84sotgds	76	14	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	76	15	)	)	-RRB-
cord-267965-84sotgds	76	16	,	,	,
cord-267965-84sotgds	76	17	was	be	VBD
cord-267965-84sotgds	76	18	created	create	VBN
cord-267965-84sotgds	76	19	by	by	IN
cord-267965-84sotgds	76	20	Donald	Donald	NNP
cord-267965-84sotgds	76	21	Bailey	Bailey	NNP
cord-267965-84sotgds	76	22	to	to	TO
cord-267965-84sotgds	76	23	facilitate	facilitate	VB
cord-267965-84sotgds	76	24	mapping	mapping	NN
cord-267965-84sotgds	76	25	of	of	IN
cord-267965-84sotgds	76	26	the	the	DT
cord-267965-84sotgds	76	27	MHC	MHC	NNP
cord-267965-84sotgds	76	28	locus	locus	NN
cord-267965-84sotgds	76	29	(	(	-LRB-
cord-267965-84sotgds	76	30	Bailey	Bailey	NNP
cord-267965-84sotgds	76	31	,	,	,
cord-267965-84sotgds	76	32	1971	1971	CD
cord-267965-84sotgds	76	33	)	)	-RRB-
cord-267965-84sotgds	76	34	.	.	.
cord-267965-84sotgds	77	1	Subsequent	subsequent	JJ
cord-267965-84sotgds	77	2	biparental	biparental	JJ
cord-267965-84sotgds	77	3	recombinant	recombinant	JJ
cord-267965-84sotgds	77	4	inbred	inbred	JJ
cord-267965-84sotgds	77	5	panels	panel	NNS
cord-267965-84sotgds	77	6	include	include	VBP
cord-267965-84sotgds	77	7	the	the	DT
cord-267965-84sotgds	77	8	AXB	AXB	NNP
cord-267965-84sotgds	77	9	/	/	SYM
cord-267965-84sotgds	77	10	BXA	BXA	NNP
cord-267965-84sotgds	77	11	(	(	-LRB-
cord-267965-84sotgds	77	12	A	A	NNP
cord-267965-84sotgds	77	13	/	/	SYM
cord-267965-84sotgds	77	14	J	J	NNP
cord-267965-84sotgds	77	15	3	3	CD
cord-267965-84sotgds	77	16	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	77	17	,	,	,
cord-267965-84sotgds	77	18	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	77	19	3	3	CD
cord-267965-84sotgds	77	20	A	A	NNP
cord-267965-84sotgds	77	21	/	/	SYM
cord-267965-84sotgds	77	22	J	J	NNP
cord-267965-84sotgds	77	23	)	)	-RRB-
cord-267965-84sotgds	77	24	,	,	,
cord-267965-84sotgds	77	25	the	the	DT
cord-267965-84sotgds	77	26	BXH	BXH	NNP
cord-267965-84sotgds	77	27	(	(	-LRB-
cord-267965-84sotgds	77	28	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	77	29	3	3	CD
cord-267965-84sotgds	77	30	C3H	C3H	NNP
cord-267965-84sotgds	77	31	/	/	SYM
cord-267965-84sotgds	77	32	HeJ	HeJ	NNP
cord-267965-84sotgds	77	33	)	)	-RRB-
cord-267965-84sotgds	77	34	,	,	,
cord-267965-84sotgds	77	35	and	and	CC
cord-267965-84sotgds	77	36	the	the	DT
cord-267965-84sotgds	77	37	BXD	BXD	NNP
cord-267965-84sotgds	77	38	(	(	-LRB-
cord-267965-84sotgds	77	39	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	77	40	3	3	CD
cord-267965-84sotgds	77	41	DBA/2J	DBA/2J	NNS
cord-267965-84sotgds	77	42	)	)	-RRB-
cord-267965-84sotgds	77	43	,	,	,
cord-267965-84sotgds	77	44	which	which	WDT
cord-267965-84sotgds	77	45	is	be	VBZ
cord-267965-84sotgds	77	46	the	the	DT
cord-267965-84sotgds	77	47	largest	large	JJS
cord-267965-84sotgds	77	48	and	and	CC
cord-267965-84sotgds	77	49	most	most	RBS
cord-267965-84sotgds	77	50	extensively	extensively	RB
cord-267965-84sotgds	77	51	used	use	VBN
cord-267965-84sotgds	77	52	of	of	IN
cord-267965-84sotgds	77	53	these	these	DT
cord-267965-84sotgds	77	54	panels	panel	NNS
cord-267965-84sotgds	77	55	(	(	-LRB-
cord-267965-84sotgds	77	56	Peirce	Peirce	NNP
cord-267965-84sotgds	77	57	et	et	NNP
cord-267965-84sotgds	77	58	al	al	NNP
cord-267965-84sotgds	77	59	.	.	NNP
cord-267965-84sotgds	77	60	,	,	,
cord-267965-84sotgds	77	61	2004	2004	CD
cord-267965-84sotgds	77	62	)	)	-RRB-
cord-267965-84sotgds	77	63	.	.	.
cord-267965-84sotgds	78	1	Though	though	IN
cord-267965-84sotgds	78	2	originally	originally	RB
cord-267965-84sotgds	78	3	developed	develop	VBN
cord-267965-84sotgds	78	4	to	to	TO
cord-267965-84sotgds	78	5	study	study	VB
cord-267965-84sotgds	78	6	monogenic	monogenic	JJ
cord-267965-84sotgds	78	7	traits	trait	NNS
cord-267965-84sotgds	78	8	,	,	,
cord-267965-84sotgds	78	9	use	use	NN
cord-267965-84sotgds	78	10	of	of	IN
cord-267965-84sotgds	78	11	these	these	DT
cord-267965-84sotgds	78	12	panels	panel	NNS
cord-267965-84sotgds	78	13	has	have	VBZ
cord-267965-84sotgds	78	14	been	be	VBN
cord-267965-84sotgds	78	15	extended	extend	VBN
cord-267965-84sotgds	78	16	to	to	TO
cord-267965-84sotgds	78	17	study	study	VB
cord-267965-84sotgds	78	18	genetically	genetically	RB
cord-267965-84sotgds	78	19	complex	complex	JJ
cord-267965-84sotgds	78	20	traits	trait	NNS
cord-267965-84sotgds	78	21	such	such	JJ
cord-267965-84sotgds	78	22	as	as	IN
cord-267965-84sotgds	78	23	susceptibility	susceptibility	NN
cord-267965-84sotgds	78	24	to	to	IN
cord-267965-84sotgds	78	25	murine	murine	JJ
cord-267965-84sotgds	78	26	plasmodia	plasmodia	NNP
cord-267965-84sotgds	79	1	(	(	-LRB-
cord-267965-84sotgds	79	2	Hoffmann	Hoffmann	NNP
cord-267965-84sotgds	79	3	et	et	NNP
cord-267965-84sotgds	79	4	al	al	NNP
cord-267965-84sotgds	79	5	.	.	NNP
cord-267965-84sotgds	79	6	,	,	,
cord-267965-84sotgds	79	7	1984	1984	CD
cord-267965-84sotgds	79	8	)	)	-RRB-
cord-267965-84sotgds	79	9	,	,	,
cord-267965-84sotgds	79	10	murine	murine	JJ
cord-267965-84sotgds	79	11	leukemia	leukemia	NN
cord-267965-84sotgds	79	12	virus	virus	NN
cord-267965-84sotgds	80	1	(	(	-LRB-
cord-267965-84sotgds	80	2	Panoutsakopoulou	Panoutsakopoulou	NNP
cord-267965-84sotgds	80	3	et	et	NNP
cord-267965-84sotgds	80	4	al	al	NNP
cord-267965-84sotgds	80	5	.	.	NNP
cord-267965-84sotgds	80	6	,	,	,
cord-267965-84sotgds	80	7	1998	1998	CD
cord-267965-84sotgds	80	8	)	)	-RRB-
cord-267965-84sotgds	80	9	,	,	,
cord-267965-84sotgds	80	10	group	group	NN
cord-267965-84sotgds	80	11	A	a	DT
cord-267965-84sotgds	80	12	streptococcus	streptococcus	NN
cord-267965-84sotgds	80	13	(	(	-LRB-
cord-267965-84sotgds	80	14	Chella	Chella	NNP
cord-267965-84sotgds	80	15	Krishnan	Krishnan	NNP
cord-267965-84sotgds	80	16	et	et	NNP
cord-267965-84sotgds	80	17	al	al	NNP
cord-267965-84sotgds	80	18	.	.	NNP
cord-267965-84sotgds	80	19	,	,	,
cord-267965-84sotgds	80	20	2016	2016	CD
cord-267965-84sotgds	80	21	)	)	-RRB-
cord-267965-84sotgds	80	22	,	,	,
cord-267965-84sotgds	80	23	and	and	CC
cord-267965-84sotgds	80	24	influenza	influenza	VB
cord-267965-84sotgds	80	25	A	a	DT
cord-267965-84sotgds	80	26	virus	virus	NN
cord-267965-84sotgds	80	27	(	(	-LRB-
cord-267965-84sotgds	80	28	IAV	iav	NN
cord-267965-84sotgds	80	29	)	)	-RRB-
cord-267965-84sotgds	81	1	(	(	-LRB-
cord-267965-84sotgds	81	2	Nedelko	Nedelko	NNP
cord-267965-84sotgds	81	3	et	et	NNP
cord-267965-84sotgds	81	4	al	al	NNP
cord-267965-84sotgds	81	5	.	.	NNP
cord-267965-84sotgds	81	6	,	,	,
cord-267965-84sotgds	81	7	2012	2012	CD
cord-267965-84sotgds	81	8	)	)	-RRB-
cord-267965-84sotgds	81	9	.	.	.
cord-267965-84sotgds	82	1	As	as	IN
cord-267965-84sotgds	82	2	results	result	NNS
cord-267965-84sotgds	82	3	from	from	IN
cord-267965-84sotgds	82	4	these	these	DT
cord-267965-84sotgds	82	5	panels	panel	NNS
cord-267965-84sotgds	82	6	accumulated	accumulate	VBN
cord-267965-84sotgds	82	7	,	,	,
cord-267965-84sotgds	82	8	there	there	EX
cord-267965-84sotgds	82	9	was	be	VBD
cord-267965-84sotgds	82	10	a	a	DT
cord-267965-84sotgds	82	11	community	community	NN
cord-267965-84sotgds	82	12	-	-	HYPH
cord-267965-84sotgds	82	13	wide	wide	JJ
cord-267965-84sotgds	82	14	recognition	recognition	NN
cord-267965-84sotgds	82	15	that	that	IN
cord-267965-84sotgds	82	16	larger	large	JJR
cord-267965-84sotgds	82	17	and	and	CC
cord-267965-84sotgds	82	18	more	more	RBR
cord-267965-84sotgds	82	19	genetically	genetically	RB
cord-267965-84sotgds	82	20	diverse	diverse	JJ
cord-267965-84sotgds	82	21	GRPs	grp	NNS
cord-267965-84sotgds	82	22	would	would	MD
cord-267965-84sotgds	82	23	improve	improve	VB
cord-267965-84sotgds	82	24	the	the	DT
cord-267965-84sotgds	82	25	ability	ability	NN
cord-267965-84sotgds	82	26	to	to	TO
cord-267965-84sotgds	82	27	genetically	genetically	RB
cord-267965-84sotgds	82	28	dissect	dissect	VB
cord-267965-84sotgds	82	29	more	more	JJR
cord-267965-84sotgds	82	30	complex	complex	JJ
cord-267965-84sotgds	82	31	traits	trait	NNS
cord-267965-84sotgds	82	32	(	(	-LRB-
cord-267965-84sotgds	82	33	Threadgill	Threadgill	NNP
cord-267965-84sotgds	82	34	et	et	NNP
cord-267965-84sotgds	82	35	al	al	NNP
cord-267965-84sotgds	82	36	.	.	NNP
cord-267965-84sotgds	82	37	,	,	,
cord-267965-84sotgds	82	38	2002	2002	CD
cord-267965-84sotgds	82	39	)	)	-RRB-
cord-267965-84sotgds	82	40	.	.	.
cord-267965-84sotgds	83	1	Based	base	VBN
cord-267965-84sotgds	83	2	on	on	IN
cord-267965-84sotgds	83	3	results	result	NNS
cord-267965-84sotgds	83	4	from	from	IN
cord-267965-84sotgds	83	5	the	the	DT
cord-267965-84sotgds	83	6	early	early	JJ
cord-267965-84sotgds	83	7	GRPs	grp	NNS
cord-267965-84sotgds	83	8	as	as	RB
cord-267965-84sotgds	83	9	well	well	RB
cord-267965-84sotgds	83	10	as	as	IN
cord-267965-84sotgds	83	11	genetic	genetic	JJ
cord-267965-84sotgds	83	12	mapping	mapping	NN
cord-267965-84sotgds	83	13	studies	study	NNS
cord-267965-84sotgds	83	14	,	,	,
cord-267965-84sotgds	83	15	the	the	DT
cord-267965-84sotgds	83	16	Complex	Complex	NNP
cord-267965-84sotgds	83	17	Trait	Trait	NNP
cord-267965-84sotgds	83	18	Consortium	Consortium	NNP
cord-267965-84sotgds	83	19	proposed	propose	VBD
cord-267965-84sotgds	83	20	to	to	TO
cord-267965-84sotgds	83	21	create	create	VB
cord-267965-84sotgds	83	22	a	a	DT
cord-267965-84sotgds	83	23	second	second	JJ
cord-267965-84sotgds	83	24	-	-	HYPH
cord-267965-84sotgds	83	25	generation	generation	NN
cord-267965-84sotgds	83	26	,	,	,
cord-267965-84sotgds	83	27	multi	multi	JJ
cord-267965-84sotgds	83	28	-	-	JJ
cord-267965-84sotgds	83	29	parent	parent	JJ
cord-267965-84sotgds	83	30	advanced	advanced	JJ
cord-267965-84sotgds	83	31	intercross	intercross	NNP
cord-267965-84sotgds	83	32	GRP	GRP	NNP
cord-267965-84sotgds	83	33	to	to	TO
cord-267965-84sotgds	83	34	promote	promote	VB
cord-267965-84sotgds	83	35	complex	complex	JJ
cord-267965-84sotgds	83	36	trait	trait	NN
cord-267965-84sotgds	83	37	genetic	genetic	JJ
cord-267965-84sotgds	83	38	mapping	mapping	NN
cord-267965-84sotgds	83	39	and	and	CC
cord-267965-84sotgds	83	40	systems	system	NNS
cord-267965-84sotgds	83	41	genetics	genetic	NNS
cord-267965-84sotgds	83	42	research	research	NN
cord-267965-84sotgds	83	43	(	(	-LRB-
cord-267965-84sotgds	83	44	Threadgill	Threadgill	NNP
cord-267965-84sotgds	83	45	et	et	NNP
cord-267965-84sotgds	83	46	al	al	NNP
cord-267965-84sotgds	83	47	.	.	NNP
cord-267965-84sotgds	83	48	,	,	,
cord-267965-84sotgds	83	49	2002	2002	CD
cord-267965-84sotgds	83	50	)	)	-RRB-
cord-267965-84sotgds	83	51	.	.	.
cord-267965-84sotgds	84	1	In	in	IN
cord-267965-84sotgds	84	2	contrast	contrast	NN
cord-267965-84sotgds	84	3	to	to	IN
cord-267965-84sotgds	84	4	single	single	JJ
cord-267965-84sotgds	84	5	-	-	HYPH
cord-267965-84sotgds	84	6	gene	gene	NN
cord-267965-84sotgds	84	7	approaches	approach	NNS
cord-267965-84sotgds	84	8	,	,	,
cord-267965-84sotgds	84	9	systems	system	NNS
cord-267965-84sotgds	84	10	genetics	genetics	NN
cord-267965-84sotgds	84	11	considers	consider	VBZ
cord-267965-84sotgds	84	12	phenotypes	phenotype	NNS
cord-267965-84sotgds	84	13	in	in	IN
cord-267965-84sotgds	84	14	the	the	DT
cord-267965-84sotgds	84	15	context	context	NN
cord-267965-84sotgds	84	16	of	of	IN
cord-267965-84sotgds	84	17	global	global	JJ
cord-267965-84sotgds	84	18	genetic	genetic	JJ
cord-267965-84sotgds	84	19	variation	variation	NN
cord-267965-84sotgds	84	20	as	as	RB
cord-267965-84sotgds	84	21	well	well	RB
cord-267965-84sotgds	84	22	as	as	IN
cord-267965-84sotgds	84	23	intermediate	intermediate	JJ
cord-267965-84sotgds	84	24	molecular	molecular	JJ
cord-267965-84sotgds	84	25	factors	factor	NNS
cord-267965-84sotgds	84	26	such	such	JJ
cord-267965-84sotgds	84	27	as	as	IN
cord-267965-84sotgds	84	28	gene	gene	NN
cord-267965-84sotgds	84	29	expression	expression	NN
cord-267965-84sotgds	84	30	,	,	,
cord-267965-84sotgds	84	31	protein	protein	NN
cord-267965-84sotgds	84	32	abundance	abundance	NN
cord-267965-84sotgds	84	33	,	,	,
cord-267965-84sotgds	84	34	and	and	CC
cord-267965-84sotgds	84	35	environmental	environmental	JJ
cord-267965-84sotgds	84	36	interactions	interaction	NNS
cord-267965-84sotgds	84	37	.	.	.
cord-267965-84sotgds	85	1	The	the	DT
cord-267965-84sotgds	85	2	resource	resource	NN
cord-267965-84sotgds	85	3	ultimately	ultimately	RB
cord-267965-84sotgds	85	4	derived	derive	VBD
cord-267965-84sotgds	85	5	from	from	IN
cord-267965-84sotgds	85	6	this	this	DT
cord-267965-84sotgds	85	7	proposal	proposal	NN
cord-267965-84sotgds	85	8	was	be	VBD
cord-267965-84sotgds	85	9	the	the	DT
cord-267965-84sotgds	85	10	CC	CC	NNP
cord-267965-84sotgds	85	11	,	,	,
cord-267965-84sotgds	85	12	a	a	DT
cord-267965-84sotgds	85	13	large	large	JJ
cord-267965-84sotgds	85	14	panel	panel	NN
cord-267965-84sotgds	85	15	of	of	IN
cord-267965-84sotgds	85	16	recombinant	recombinant	JJ
cord-267965-84sotgds	85	17	inbred	inbred	JJ
cord-267965-84sotgds	85	18	strains	strain	NNS
cord-267965-84sotgds	85	19	derived	derive	VBN
cord-267965-84sotgds	85	20	from	from	IN
cord-267965-84sotgds	85	21	eight	eight	CD
cord-267965-84sotgds	85	22	genetically	genetically	RB
cord-267965-84sotgds	85	23	diverse	diverse	JJ
cord-267965-84sotgds	85	24	founder	founder	NN
cord-267965-84sotgds	85	25	strains	strain	NNS
cord-267965-84sotgds	85	26	.	.	.
cord-267965-84sotgds	86	1	The	the	DT
cord-267965-84sotgds	86	2	CC	CC	NNP
cord-267965-84sotgds	86	3	was	be	VBD
cord-267965-84sotgds	86	4	designed	design	VBN
cord-267965-84sotgds	86	5	to	to	TO
cord-267965-84sotgds	86	6	facilitate	facilitate	VB
cord-267965-84sotgds	86	7	systems	system	NNS
cord-267965-84sotgds	86	8	genetics	genetics	NN
cord-267965-84sotgds	86	9	approaches	approach	NNS
cord-267965-84sotgds	86	10	with	with	IN
cord-267965-84sotgds	86	11	improved	improved	JJ
cord-267965-84sotgds	86	12	resolution	resolution	NN
cord-267965-84sotgds	86	13	and	and	CC
cord-267965-84sotgds	86	14	higher	high	JJR
cord-267965-84sotgds	86	15	statistical	statistical	JJ
cord-267965-84sotgds	86	16	power	power	NN
cord-267965-84sotgds	86	17	compared	compare	VBN
cord-267965-84sotgds	86	18	to	to	IN
cord-267965-84sotgds	86	19	traditional	traditional	JJ
cord-267965-84sotgds	86	20	GRPs	grp	NNS
cord-267965-84sotgds	86	21	,	,	,
cord-267965-84sotgds	86	22	to	to	TO
cord-267965-84sotgds	86	23	expand	expand	VB
cord-267965-84sotgds	86	24	the	the	DT
cord-267965-84sotgds	86	25	pool	pool	NN
cord-267965-84sotgds	86	26	of	of	IN
cord-267965-84sotgds	86	27	genetic	genetic	JJ
cord-267965-84sotgds	86	28	variation	variation	NN
cord-267965-84sotgds	86	29	segregating	segregate	VBG
cord-267965-84sotgds	86	30	in	in	IN
cord-267965-84sotgds	86	31	the	the	DT
cord-267965-84sotgds	86	32	population	population	NN
cord-267965-84sotgds	86	33	,	,	,
cord-267965-84sotgds	86	34	and	and	CC
cord-267965-84sotgds	86	35	to	to	TO
cord-267965-84sotgds	86	36	bridge	bridge	VB
cord-267965-84sotgds	86	37	the	the	DT
cord-267965-84sotgds	86	38	analysis	analysis	NN
cord-267965-84sotgds	86	39	of	of	IN
cord-267965-84sotgds	86	40	genetic	genetic	JJ
cord-267965-84sotgds	86	41	and	and	CC
cord-267965-84sotgds	86	42	molecular	molecular	JJ
cord-267965-84sotgds	86	43	networks	network	NNS
cord-267965-84sotgds	86	44	across	across	IN
cord-267965-84sotgds	86	45	diverse	diverse	JJ
cord-267965-84sotgds	86	46	phenotypes	phenotype	NNS
cord-267965-84sotgds	86	47	(	(	-LRB-
cord-267965-84sotgds	87	1	Churchill	Churchill	NNP
cord-267965-84sotgds	87	2	et	et	NNP
cord-267965-84sotgds	87	3	al	al	NNP
cord-267965-84sotgds	87	4	.	.	NNP
cord-267965-84sotgds	87	5	,	,	,
cord-267965-84sotgds	87	6	2004	2004	CD
cord-267965-84sotgds	87	7	)	)	-RRB-
cord-267965-84sotgds	87	8	.	.	.
cord-267965-84sotgds	88	1	Of	of	IN
cord-267965-84sotgds	88	2	the	the	DT
cord-267965-84sotgds	88	3	eight	eight	CD
cord-267965-84sotgds	88	4	CC	CC	NNP
cord-267965-84sotgds	88	5	founder	founder	NN
cord-267965-84sotgds	88	6	strains	strain	NNS
cord-267965-84sotgds	88	7	,	,	,
cord-267965-84sotgds	88	8	five	five	CD
cord-267965-84sotgds	88	9	are	be	VBP
cord-267965-84sotgds	88	10	classical	classical	JJ
cord-267965-84sotgds	88	11	laboratory	laboratory	NN
cord-267965-84sotgds	88	12	strains	strain	NNS
cord-267965-84sotgds	88	13	chosen	choose	VBN
cord-267965-84sotgds	88	14	for	for	IN
cord-267965-84sotgds	88	15	their	-PRON-	PRP$
cord-267965-84sotgds	88	16	rich	rich	JJ
cord-267965-84sotgds	88	17	history	history	NN
cord-267965-84sotgds	88	18	of	of	IN
cord-267965-84sotgds	88	19	use	use	NN
cord-267965-84sotgds	88	20	in	in	IN
cord-267965-84sotgds	88	21	mouse	mouse	NN
cord-267965-84sotgds	88	22	genetics	genetic	NNS
cord-267965-84sotgds	88	23	(	(	-LRB-
cord-267965-84sotgds	89	1	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	89	2	and	and	CC
cord-267965-84sotgds	89	3	129S1	129S1	NNP
cord-267965-84sotgds	89	4	/	/	SYM
cord-267965-84sotgds	89	5	SvImJ	SvImJ	NNP
cord-267965-84sotgds	89	6	)	)	-RRB-
cord-267965-84sotgds	89	7	or	or	CC
cord-267965-84sotgds	89	8	their	-PRON-	PRP$
cord-267965-84sotgds	89	9	relevance	relevance	NN
cord-267965-84sotgds	89	10	as	as	IN
cord-267965-84sotgds	89	11	models	model	NNS
cord-267965-84sotgds	89	12	of	of	IN
cord-267965-84sotgds	89	13	common	common	JJ
cord-267965-84sotgds	89	14	diseases	disease	NNS
cord-267965-84sotgds	89	15	including	include	VBG
cord-267965-84sotgds	89	16	cancer	cancer	NN
cord-267965-84sotgds	89	17	,	,	,
cord-267965-84sotgds	89	18	type	type	NN
cord-267965-84sotgds	89	19	1	1	CD
cord-267965-84sotgds	89	20	diabetes	diabetes	NN
cord-267965-84sotgds	89	21	,	,	,
cord-267965-84sotgds	89	22	metabolic	metabolic	JJ
cord-267965-84sotgds	89	23	syndrome	syndrome	NN
cord-267965-84sotgds	89	24	,	,	,
cord-267965-84sotgds	89	25	and	and	CC
cord-267965-84sotgds	89	26	obesity	obesity	NN
cord-267965-84sotgds	89	27	(	(	-LRB-
cord-267965-84sotgds	89	28	A	A	NNP
cord-267965-84sotgds	89	29	/	/	SYM
cord-267965-84sotgds	89	30	J	J	NNP
cord-267965-84sotgds	89	31	,	,	,
cord-267965-84sotgds	89	32	NOD	NOD	NNP
cord-267965-84sotgds	89	33	/	/	SYM
cord-267965-84sotgds	89	34	ShiLtJ	shiltj	NN
cord-267965-84sotgds	89	35	,	,	,
cord-267965-84sotgds	89	36	and	and	CC
cord-267965-84sotgds	89	37	NZO	NZO	NNP
cord-267965-84sotgds	89	38	/	/	SYM
cord-267965-84sotgds	89	39	HiLtJ	HiLtJ	NNP
cord-267965-84sotgds	89	40	)	)	-RRB-
cord-267965-84sotgds	89	41	.	.	.
cord-267965-84sotgds	90	1	The	the	DT
cord-267965-84sotgds	90	2	other	other	JJ
cord-267965-84sotgds	90	3	three	three	CD
cord-267965-84sotgds	90	4	CC	CC	NNP
cord-267965-84sotgds	90	5	founders	founder	NNS
cord-267965-84sotgds	90	6	are	be	VBP
cord-267965-84sotgds	90	7	wild	wild	JJ
cord-267965-84sotgds	90	8	-	-	HYPH
cord-267965-84sotgds	90	9	derived	derive	VBN
cord-267965-84sotgds	90	10	inbred	inbred	JJ
cord-267965-84sotgds	90	11	strains	strain	NNS
cord-267965-84sotgds	90	12	,	,	,
cord-267965-84sotgds	90	13	which	which	WDT
cord-267965-84sotgds	90	14	represent	represent	VBP
cord-267965-84sotgds	90	15	the	the	DT
cord-267965-84sotgds	90	16	three	three	CD
cord-267965-84sotgds	90	17	major	major	JJ
cord-267965-84sotgds	90	18	subspecies	subspecie	NNS
cord-267965-84sotgds	90	19	of	of	IN
cord-267965-84sotgds	90	20	Mus	Mus	NNP
cord-267965-84sotgds	90	21	musculus	musculus	NN
cord-267965-84sotgds	90	22	:	:	:
cord-267965-84sotgds	90	23	casteneus	casteneus	NNP
cord-267965-84sotgds	90	24	(	(	-LRB-
cord-267965-84sotgds	90	25	CAST	cast	NN
cord-267965-84sotgds	90	26	/	/	SYM
cord-267965-84sotgds	90	27	EiJ	eij	NN
cord-267965-84sotgds	90	28	)	)	-RRB-
cord-267965-84sotgds	90	29	,	,	,
cord-267965-84sotgds	90	30	musculus	musculus	NN
cord-267965-84sotgds	90	31	(	(	-LRB-
cord-267965-84sotgds	90	32	PWK	PWK	NNP
cord-267965-84sotgds	90	33	/	/	SYM
cord-267965-84sotgds	90	34	PhJ	PhJ	NNP
cord-267965-84sotgds	90	35	)	)	-RRB-
cord-267965-84sotgds	90	36	,	,	,
cord-267965-84sotgds	90	37	and	and	CC
cord-267965-84sotgds	90	38	domesticus	domesticus	NN
cord-267965-84sotgds	90	39	(	(	-LRB-
cord-267965-84sotgds	90	40	WSB	WSB	NNP
cord-267965-84sotgds	90	41	/	/	SYM
cord-267965-84sotgds	90	42	EiJ	eij	NN
cord-267965-84sotgds	90	43	)	)	-RRB-
cord-267965-84sotgds	90	44	,	,	,
cord-267965-84sotgds	90	45	and	and	CC
cord-267965-84sotgds	90	46	introduce	introduce	VB
cord-267965-84sotgds	90	47	much	much	JJ
cord-267965-84sotgds	90	48	of	of	IN
cord-267965-84sotgds	90	49	the	the	DT
cord-267965-84sotgds	90	50	genetic	genetic	JJ
cord-267965-84sotgds	90	51	diversity	diversity	NN
cord-267965-84sotgds	90	52	into	into	IN
cord-267965-84sotgds	90	53	the	the	DT
cord-267965-84sotgds	90	54	CC	cc	NN
cord-267965-84sotgds	90	55	.	.	.
cord-267965-84sotgds	91	1	These	these	DT
cord-267965-84sotgds	91	2	eight	eight	CD
cord-267965-84sotgds	91	3	founder	founder	NN
cord-267965-84sotgds	91	4	strains	strain	NNS
cord-267965-84sotgds	91	5	were	be	VBD
cord-267965-84sotgds	91	6	interbred	interbreed	VBN
cord-267965-84sotgds	91	7	in	in	IN
cord-267965-84sotgds	91	8	a	a	DT
cord-267965-84sotgds	91	9	funnel	funnel	NN
cord-267965-84sotgds	91	10	breeding	breeding	NN
cord-267965-84sotgds	91	11	scheme	scheme	NN
cord-267965-84sotgds	91	12	to	to	TO
cord-267965-84sotgds	91	13	produce	produce	VB
cord-267965-84sotgds	91	14	recombinant	recombinant	JJ
cord-267965-84sotgds	91	15	mice	mouse	NNS
cord-267965-84sotgds	91	16	with	with	IN
cord-267965-84sotgds	91	17	genomic	genomic	JJ
cord-267965-84sotgds	91	18	contributions	contribution	NNS
cord-267965-84sotgds	91	19	from	from	IN
cord-267965-84sotgds	91	20	each	each	DT
cord-267965-84sotgds	91	21	founder	founder	NN
cord-267965-84sotgds	91	22	,	,	,
cord-267965-84sotgds	91	23	which	which	WDT
cord-267965-84sotgds	91	24	were	be	VBD
cord-267965-84sotgds	91	25	then	then	RB
cord-267965-84sotgds	91	26	bred	breed	VBN
cord-267965-84sotgds	91	27	to	to	IN
cord-267965-84sotgds	91	28	homozygosity	homozygosity	NN
cord-267965-84sotgds	91	29	to	to	TO
cord-267965-84sotgds	91	30	produce	produce	VB
cord-267965-84sotgds	91	31	recombinant	recombinant	JJ
cord-267965-84sotgds	91	32	inbred	inbred	JJ
cord-267965-84sotgds	91	33	(	(	-LRB-
cord-267965-84sotgds	91	34	RI	RI	NNP
cord-267965-84sotgds	91	35	)	)	-RRB-
cord-267965-84sotgds	91	36	CC	cc	NN
cord-267965-84sotgds	91	37	strains	strain	NNS
cord-267965-84sotgds	91	38	(	(	-LRB-
cord-267965-84sotgds	91	39	Figure	figure	NN
cord-267965-84sotgds	91	40	1	1	CD
cord-267965-84sotgds	91	41	)	)	-RRB-
cord-267965-84sotgds	91	42	.	.	.
cord-267965-84sotgds	92	1	Although	although	IN
cord-267965-84sotgds	92	2	the	the	DT
cord-267965-84sotgds	92	3	initial	initial	JJ
cord-267965-84sotgds	92	4	goal	goal	NN
cord-267965-84sotgds	92	5	was	be	VBD
cord-267965-84sotgds	92	6	to	to	TO
cord-267965-84sotgds	92	7	produce	produce	VB
cord-267965-84sotgds	92	8	1,000	1,000	CD
cord-267965-84sotgds	92	9	CC	cc	NN
cord-267965-84sotgds	92	10	strains	strain	NNS
cord-267965-84sotgds	92	11	,	,	,
cord-267965-84sotgds	92	12	only	only	RB
cord-267965-84sotgds	92	13	around	around	IN
cord-267965-84sotgds	92	14	100	100	CD
cord-267965-84sotgds	92	15	CC	cc	NN
cord-267965-84sotgds	92	16	strains	strain	NNS
cord-267965-84sotgds	92	17	survived	survive	VBD
cord-267965-84sotgds	92	18	the	the	DT
cord-267965-84sotgds	92	19	inbreeding	inbreeding	NN
cord-267965-84sotgds	92	20	process	process	NN
cord-267965-84sotgds	92	21	due	due	IN
cord-267965-84sotgds	92	22	to	to	IN
cord-267965-84sotgds	92	23	high	high	JJ
cord-267965-84sotgds	92	24	rates	rate	NNS
cord-267965-84sotgds	92	25	of	of	IN
cord-267965-84sotgds	92	26	infertility	infertility	NN
cord-267965-84sotgds	92	27	and	and	CC
cord-267965-84sotgds	92	28	breeding	breeding	NN
cord-267965-84sotgds	92	29	issues	issue	NNS
cord-267965-84sotgds	92	30	,	,	,
cord-267965-84sotgds	92	31	largely	largely	RB
cord-267965-84sotgds	92	32	caused	cause	VBN
cord-267965-84sotgds	92	33	by	by	IN
cord-267965-84sotgds	92	34	genomic	genomic	JJ
cord-267965-84sotgds	92	35	incompatibility	incompatibility	NN
cord-267965-84sotgds	92	36	introduced	introduce	VBN
cord-267965-84sotgds	92	37	by	by	IN
cord-267965-84sotgds	92	38	the	the	DT
cord-267965-84sotgds	92	39	wild	wild	NN
cord-267965-84sotgds	92	40	-	-	HYPH
cord-267965-84sotgds	92	41	derived	derive	VBN
cord-267965-84sotgds	92	42	strains	strain	NNS
cord-267965-84sotgds	92	43	.	.	.
cord-267965-84sotgds	93	1	Extinction	extinction	NN
cord-267965-84sotgds	93	2	of	of	IN
cord-267965-84sotgds	93	3	CC	CC	NNP
cord-267965-84sotgds	93	4	strains	strain	NNS
cord-267965-84sotgds	93	5	during	during	IN
cord-267965-84sotgds	93	6	the	the	DT
cord-267965-84sotgds	93	7	inbreeding	inbreeding	NN
cord-267965-84sotgds	93	8	process	process	NN
cord-267965-84sotgds	93	9	inspired	inspire	VBD
cord-267965-84sotgds	93	10	the	the	DT
cord-267965-84sotgds	93	11	creation	creation	NN
cord-267965-84sotgds	93	12	of	of	IN
cord-267965-84sotgds	93	13	the	the	DT
cord-267965-84sotgds	93	14	Diversity	Diversity	NNP
cord-267965-84sotgds	93	15	Outbred	Outbred	NNP
cord-267965-84sotgds	93	16	(	(	-LRB-
cord-267965-84sotgds	93	17	DO	DO	NNP
cord-267965-84sotgds	93	18	)	)	-RRB-
cord-267965-84sotgds	93	19	panel	panel	NN
cord-267965-84sotgds	93	20	,	,	,
cord-267965-84sotgds	93	21	an	an	DT
cord-267965-84sotgds	93	22	outbred	outbred	JJ
cord-267965-84sotgds	93	23	population	population	NN
cord-267965-84sotgds	93	24	derived	derive	VBN
cord-267965-84sotgds	93	25	from	from	IN
cord-267965-84sotgds	93	26	a	a	DT
cord-267965-84sotgds	93	27	set	set	NN
cord-267965-84sotgds	93	28	of	of	IN
cord-267965-84sotgds	93	29	incipient	incipient	JJ
cord-267965-84sotgds	93	30	CC	cc	NN
cord-267965-84sotgds	93	31	strains	strain	NNS
cord-267965-84sotgds	93	32	(	(	-LRB-
cord-267965-84sotgds	93	33	Churchill	Churchill	NNP
cord-267965-84sotgds	93	34	et	et	NNP
cord-267965-84sotgds	93	35	al	al	NNP
cord-267965-84sotgds	93	36	.	.	NNP
cord-267965-84sotgds	93	37	,	,	,
cord-267965-84sotgds	93	38	2012	2012	CD
cord-267965-84sotgds	93	39	)	)	-RRB-
cord-267965-84sotgds	93	40	.	.	.
cord-267965-84sotgds	94	1	The	the	DT
cord-267965-84sotgds	94	2	DO	DO	NNP
cord-267965-84sotgds	94	3	now	now	RB
cord-267965-84sotgds	94	4	serves	serve	VBZ
cord-267965-84sotgds	94	5	as	as	IN
cord-267965-84sotgds	94	6	its	-PRON-	PRP$
cord-267965-84sotgds	94	7	own	own	JJ
cord-267965-84sotgds	94	8	important	important	JJ
cord-267965-84sotgds	94	9	genetic	genetic	JJ
cord-267965-84sotgds	94	10	resource	resource	NN
cord-267965-84sotgds	94	11	that	that	WDT
cord-267965-84sotgds	94	12	has	have	VBZ
cord-267965-84sotgds	94	13	proven	prove	VBN
cord-267965-84sotgds	94	14	useful	useful	JJ
cord-267965-84sotgds	94	15	for	for	IN
cord-267965-84sotgds	94	16	high	high	JJ
cord-267965-84sotgds	94	17	-	-	HYPH
cord-267965-84sotgds	94	18	resolution	resolution	NN
cord-267965-84sotgds	94	19	genetic	genetic	JJ
cord-267965-84sotgds	94	20	mapping	mapping	NN
cord-267965-84sotgds	94	21	as	as	RB
cord-267965-84sotgds	94	22	well	well	RB
cord-267965-84sotgds	94	23	as	as	IN
cord-267965-84sotgds	94	24	exploration	exploration	NN
cord-267965-84sotgds	94	25	of	of	IN
cord-267965-84sotgds	94	26	phenotypic	phenotypic	JJ
cord-267965-84sotgds	94	27	diversity	diversity	NN
cord-267965-84sotgds	94	28	(	(	-LRB-
cord-267965-84sotgds	94	29	While	while	IN
cord-267965-84sotgds	94	30	the	the	DT
cord-267965-84sotgds	94	31	DO	DO	NNP
cord-267965-84sotgds	94	32	has	have	VBZ
cord-267965-84sotgds	94	33	only	only	RB
cord-267965-84sotgds	94	34	been	be	VBN
cord-267965-84sotgds	94	35	used	use	VBN
cord-267965-84sotgds	94	36	in	in	IN
cord-267965-84sotgds	94	37	a	a	DT
cord-267965-84sotgds	94	38	limited	limited	JJ
cord-267965-84sotgds	94	39	number	number	NN
cord-267965-84sotgds	94	40	of	of	IN
cord-267965-84sotgds	94	41	infectious	infectious	JJ
cord-267965-84sotgds	94	42	disease	disease	NN
cord-267965-84sotgds	94	43	studies	study	NNS
cord-267965-84sotgds	94	44	(	(	-LRB-
cord-267965-84sotgds	94	45	McHugh	McHugh	NNP
cord-267965-84sotgds	94	46	et	et	NNP
cord-267965-84sotgds	94	47	al	al	NNP
cord-267965-84sotgds	94	48	.	.	NNP
cord-267965-84sotgds	94	49	,	,	,
cord-267965-84sotgds	94	50	2013	2013	CD
cord-267965-84sotgds	94	51	;	;	:
cord-267965-84sotgds	95	1	Niazi	Niazi	NNP
cord-267965-84sotgds	95	2	et	et	IN
cord-267965-84sotgds	95	3	al	al	NNP
cord-267965-84sotgds	95	4	.	.	.
cord-267965-84sotgds	96	1	,	,	,
cord-267965-84sotgds	96	2	2015	2015	CD
cord-267965-84sotgds	96	3	)	)	-RRB-
cord-267965-84sotgds	96	4	,	,	,
cord-267965-84sotgds	96	5	the	the	DT
cord-267965-84sotgds	96	6	DO	DO	NNP
cord-267965-84sotgds	96	7	and	and	CC
cord-267965-84sotgds	96	8	CC	CC	NNP
cord-267965-84sotgds	96	9	should	should	MD
cord-267965-84sotgds	96	10	be	be	VB
cord-267965-84sotgds	96	11	viewed	view	VBN
cord-267965-84sotgds	96	12	as	as	IN
cord-267965-84sotgds	96	13	complementary	complementary	JJ
cord-267965-84sotgds	96	14	resources	resource	NNS
cord-267965-84sotgds	96	15	for	for	IN
cord-267965-84sotgds	96	16	studying	study	VBG
cord-267965-84sotgds	96	17	how	how	WRB
cord-267965-84sotgds	96	18	genetic	genetic	JJ
cord-267965-84sotgds	96	19	variation	variation	NN
cord-267965-84sotgds	96	20	affects	affect	VBZ
cord-267965-84sotgds	96	21	pathogen	pathogen	NN
cord-267965-84sotgds	96	22	susceptibility	susceptibility	NN
cord-267965-84sotgds	96	23	and	and	CC
cord-267965-84sotgds	96	24	immunity	immunity	NN
cord-267965-84sotgds	96	25	.	.	.
cord-267965-84sotgds	97	1	While	while	IN
cord-267965-84sotgds	97	2	classical	classical	JJ
cord-267965-84sotgds	97	3	mouse	mouse	NN
cord-267965-84sotgds	97	4	GRPs	grp	NNS
cord-267965-84sotgds	97	5	remain	remain	VBP
cord-267965-84sotgds	97	6	actively	actively	RB
cord-267965-84sotgds	97	7	used	use	VBN
cord-267965-84sotgds	97	8	,	,	,
cord-267965-84sotgds	97	9	and	and	CC
cord-267965-84sotgds	97	10	in	in	IN
cord-267965-84sotgds	97	11	some	some	DT
cord-267965-84sotgds	97	12	ways	way	NNS
cord-267965-84sotgds	97	13	provide	provide	VBP
cord-267965-84sotgds	97	14	a	a	DT
cord-267965-84sotgds	97	15	more	more	RBR
cord-267965-84sotgds	97	16	straightforward	straightforward	JJ
cord-267965-84sotgds	97	17	analytical	analytical	JJ
cord-267965-84sotgds	97	18	path	path	NN
cord-267965-84sotgds	97	19	than	than	IN
cord-267965-84sotgds	97	20	the	the	DT
cord-267965-84sotgds	97	21	CC	CC	NNP
cord-267965-84sotgds	97	22	due	due	JJ
cord-267965-84sotgds	97	23	to	to	IN
cord-267965-84sotgds	97	24	reduced	reduce	VBN
cord-267965-84sotgds	97	25	complexity	complexity	NN
cord-267965-84sotgds	97	26	,	,	,
cord-267965-84sotgds	97	27	several	several	JJ
cord-267965-84sotgds	97	28	aspects	aspect	NNS
cord-267965-84sotgds	97	29	of	of	IN
cord-267965-84sotgds	97	30	the	the	DT
cord-267965-84sotgds	97	31	CC	CC	NNP
cord-267965-84sotgds	97	32	make	make	VB
cord-267965-84sotgds	97	33	it	-PRON-	PRP
cord-267965-84sotgds	97	34	more	more	RBR
cord-267965-84sotgds	97	35	attractive	attractive	JJ
cord-267965-84sotgds	97	36	for	for	IN
cord-267965-84sotgds	97	37	discovery	discovery	NN
cord-267965-84sotgds	97	38	-	-	HYPH
cord-267965-84sotgds	97	39	based	base	VBN
cord-267965-84sotgds	97	40	research	research	NN
cord-267965-84sotgds	97	41	.	.	.
cord-267965-84sotgds	98	1	The	the	DT
cord-267965-84sotgds	98	2	CC	CC	NNP
cord-267965-84sotgds	98	3	captures	capture	VBZ
cord-267965-84sotgds	98	4	approximately	approximately	RB
cord-267965-84sotgds	98	5	90	90	CD
cord-267965-84sotgds	98	6	%	%	NN
cord-267965-84sotgds	98	7	of	of	IN
cord-267965-84sotgds	98	8	common	common	JJ
cord-267965-84sotgds	98	9	genetic	genetic	JJ
cord-267965-84sotgds	98	10	variants	variant	NNS
cord-267965-84sotgds	98	11	described	describe	VBN
cord-267965-84sotgds	98	12	within	within	IN
cord-267965-84sotgds	98	13	laboratory	laboratory	NN
cord-267965-84sotgds	98	14	mice	mouse	NNS
cord-267965-84sotgds	98	15	,	,	,
cord-267965-84sotgds	98	16	with	with	IN
cord-267965-84sotgds	98	17	up	up	IN
cord-267965-84sotgds	98	18	to	to	TO
cord-267965-84sotgds	98	19	eight	eight	CD
cord-267965-84sotgds	98	20	distinct	distinct	JJ
cord-267965-84sotgds	98	21	haplotypes	haplotype	NNS
cord-267965-84sotgds	98	22	at	at	IN
cord-267965-84sotgds	98	23	any	any	DT
cord-267965-84sotgds	98	24	region	region	NN
cord-267965-84sotgds	98	25	of	of	IN
cord-267965-84sotgds	98	26	the	the	DT
cord-267965-84sotgds	98	27	genome	genome	NN
cord-267965-84sotgds	99	1	(	(	-LRB-
cord-267965-84sotgds	99	2	Roberts	Roberts	NNP
cord-267965-84sotgds	99	3	et	et	NNP
cord-267965-84sotgds	99	4	al	al	NNP
cord-267965-84sotgds	99	5	.	.	NNP
cord-267965-84sotgds	99	6	,	,	,
cord-267965-84sotgds	99	7	2007	2007	CD
cord-267965-84sotgds	99	8	)	)	-RRB-
cord-267965-84sotgds	99	9	.	.	.
cord-267965-84sotgds	100	1	Due	due	IN
cord-267965-84sotgds	100	2	to	to	IN
cord-267965-84sotgds	100	3	higher	high	JJR
cord-267965-84sotgds	100	4	genetic	genetic	JJ
cord-267965-84sotgds	100	5	diversity	diversity	NN
cord-267965-84sotgds	100	6	with	with	IN
cord-267965-84sotgds	100	7	novel	novel	JJ
cord-267965-84sotgds	100	8	allele	allele	NN
cord-267965-84sotgds	100	9	combinations	combination	NNS
cord-267965-84sotgds	100	10	and	and	CC
cord-267965-84sotgds	100	11	epistatic	epistatic	JJ
cord-267965-84sotgds	100	12	interactions	interaction	NNS
cord-267965-84sotgds	100	13	,	,	,
cord-267965-84sotgds	100	14	the	the	DT
cord-267965-84sotgds	100	15	CC	CC	NNP
cord-267965-84sotgds	100	16	yields	yield	VBZ
cord-267965-84sotgds	100	17	more	more	JJR
cord-267965-84sotgds	100	18	phenotypic	phenotypic	JJ
cord-267965-84sotgds	100	19	variation	variation	NN
cord-267965-84sotgds	100	20	and	and	CC
cord-267965-84sotgds	100	21	extreme	extreme	JJ
cord-267965-84sotgds	100	22	phenotypes	phenotype	NNS
cord-267965-84sotgds	100	23	than	than	IN
cord-267965-84sotgds	100	24	classical	classical	JJ
cord-267965-84sotgds	100	25	GRPs	grp	NNS
cord-267965-84sotgds	100	26	.	.	.
cord-267965-84sotgds	101	1	The	the	DT
cord-267965-84sotgds	101	2	selection	selection	NN
cord-267965-84sotgds	101	3	of	of	IN
cord-267965-84sotgds	101	4	founder	founder	NN
cord-267965-84sotgds	101	5	strains	strain	NNS
cord-267965-84sotgds	101	6	and	and	CC
cord-267965-84sotgds	101	7	the	the	DT
cord-267965-84sotgds	101	8	breeding	breeding	NN
cord-267965-84sotgds	101	9	design	design	NN
cord-267965-84sotgds	101	10	,	,	,
cord-267965-84sotgds	101	11	as	as	RB
cord-267965-84sotgds	101	12	well	well	RB
cord-267965-84sotgds	101	13	as	as	IN
cord-267965-84sotgds	101	14	higher	high	JJR
cord-267965-84sotgds	101	15	levels	level	NNS
cord-267965-84sotgds	101	16	of	of	IN
cord-267965-84sotgds	101	17	recombination	recombination	NN
cord-267965-84sotgds	101	18	,	,	,
cord-267965-84sotgds	101	19	result	result	VBP
cord-267965-84sotgds	101	20	in	in	IN
cord-267965-84sotgds	101	21	lower	low	JJR
cord-267965-84sotgds	101	22	levels	level	NNS
cord-267965-84sotgds	101	23	of	of	IN
cord-267965-84sotgds	101	24	long	long	JJ
cord-267965-84sotgds	101	25	-	-	HYPH
cord-267965-84sotgds	101	26	range	range	NN
cord-267965-84sotgds	101	27	disequilibrium	disequilibrium	NN
cord-267965-84sotgds	101	28	and	and	CC
cord-267965-84sotgds	101	29	population	population	NN
cord-267965-84sotgds	101	30	structure	structure	NN
cord-267965-84sotgds	101	31	than	than	IN
cord-267965-84sotgds	101	32	classical	classical	JJ
cord-267965-84sotgds	101	33	GRPs	grp	NNS
cord-267965-84sotgds	101	34	,	,	,
cord-267965-84sotgds	101	35	allowing	allow	VBG
cord-267965-84sotgds	101	36	for	for	IN
cord-267965-84sotgds	101	37	higher	high	JJR
cord-267965-84sotgds	101	38	resolution	resolution	NN
cord-267965-84sotgds	101	39	quantitative	quantitative	JJ
cord-267965-84sotgds	101	40	trait	trait	NN
cord-267965-84sotgds	101	41	locus	locus	NN
cord-267965-84sotgds	101	42	(	(	-LRB-
cord-267965-84sotgds	101	43	QTL	QTL	NNP
cord-267965-84sotgds	101	44	)	)	-RRB-
cord-267965-84sotgds	101	45	mapping	mapping	NN
cord-267965-84sotgds	101	46	(	(	-LRB-
cord-267965-84sotgds	101	47	Iraqi	iraqi	JJ
cord-267965-84sotgds	101	48	et	et	NNP
cord-267965-84sotgds	101	49	al	al	NNP
cord-267965-84sotgds	101	50	.	.	NNP
cord-267965-84sotgds	101	51	,	,	,
cord-267965-84sotgds	101	52	2012	2012	CD
cord-267965-84sotgds	101	53	;	;	:
cord-267965-84sotgds	101	54	Threadgill	Threadgill	NNP
cord-267965-84sotgds	101	55	et	et	NNP
cord-267965-84sotgds	101	56	al	al	NNP
cord-267965-84sotgds	101	57	.	.	NNP
cord-267965-84sotgds	101	58	,	,	,
cord-267965-84sotgds	101	59	2002	2002	CD
cord-267965-84sotgds	101	60	)	)	-RRB-
cord-267965-84sotgds	101	61	.	.	.
cord-267965-84sotgds	102	1	Genetic	genetic	JJ
cord-267965-84sotgds	102	2	variation	variation	NN
cord-267965-84sotgds	102	3	is	be	VBZ
cord-267965-84sotgds	102	4	also	also	RB
cord-267965-84sotgds	102	5	more	more	RBR
cord-267965-84sotgds	102	6	uniformly	uniformly	RB
cord-267965-84sotgds	102	7	distributed	distribute	VBN
cord-267965-84sotgds	102	8	across	across	IN
cord-267965-84sotgds	102	9	the	the	DT
cord-267965-84sotgds	102	10	genome	genome	NN
cord-267965-84sotgds	102	11	,	,	,
cord-267965-84sotgds	102	12	removing	remove	VBG
cord-267965-84sotgds	102	13	several	several	JJ
cord-267965-84sotgds	102	14	genomic	genomic	NNS
cord-267965-84sotgds	102	15	'	'	''
cord-267965-84sotgds	102	16	'	'	``
cord-267965-84sotgds	102	17	blind	blind	JJ
cord-267965-84sotgds	102	18	spots	spot	NNS
cord-267965-84sotgds	102	19	'	'	''
cord-267965-84sotgds	102	20	'	'	''
cord-267965-84sotgds	102	21	that	that	WDT
cord-267965-84sotgds	102	22	interfere	interfere	VBP
cord-267965-84sotgds	102	23	with	with	IN
cord-267965-84sotgds	102	24	mapping	mapping	NN
cord-267965-84sotgds	102	25	in	in	IN
cord-267965-84sotgds	102	26	classical	classical	JJ
cord-267965-84sotgds	102	27	inbred	inbred	JJ
cord-267965-84sotgds	102	28	strains	strain	NNS
cord-267965-84sotgds	102	29	and	and	CC
cord-267965-84sotgds	102	30	GRPs	grp	NNS
cord-267965-84sotgds	102	31	(	(	-LRB-
cord-267965-84sotgds	102	32	Roberts	Roberts	NNP
cord-267965-84sotgds	102	33	et	et	NNP
cord-267965-84sotgds	102	34	al	al	NNP
cord-267965-84sotgds	102	35	.	.	NNP
cord-267965-84sotgds	102	36	,	,	,
cord-267965-84sotgds	102	37	2007	2007	CD
cord-267965-84sotgds	102	38	)	)	-RRB-
cord-267965-84sotgds	102	39	.	.	.
cord-267965-84sotgds	103	1	Although	although	IN
cord-267965-84sotgds	103	2	the	the	DT
cord-267965-84sotgds	103	3	CC	CC	NNP
cord-267965-84sotgds	103	4	has	have	VBZ
cord-267965-84sotgds	103	5	only	only	RB
cord-267965-84sotgds	103	6	been	be	VBN
cord-267965-84sotgds	103	7	available	available	JJ
cord-267965-84sotgds	103	8	for	for	IN
cord-267965-84sotgds	103	9	a	a	DT
cord-267965-84sotgds	103	10	relatively	relatively	RB
cord-267965-84sotgds	103	11	short	short	JJ
cord-267965-84sotgds	103	12	period	period	NN
cord-267965-84sotgds	103	13	of	of	IN
cord-267965-84sotgds	103	14	time	time	NN
cord-267965-84sotgds	103	15	,	,	,
cord-267965-84sotgds	103	16	it	-PRON-	PRP
cord-267965-84sotgds	103	17	has	have	VBZ
cord-267965-84sotgds	103	18	been	be	VBN
cord-267965-84sotgds	103	19	utilized	utilize	VBN
cord-267965-84sotgds	103	20	across	across	IN
cord-267965-84sotgds	103	21	a	a	DT
cord-267965-84sotgds	103	22	number	number	NN
cord-267965-84sotgds	103	23	of	of	IN
cord-267965-84sotgds	103	24	disciplines	discipline	NNS
cord-267965-84sotgds	103	25	,	,	,
cord-267965-84sotgds	103	26	including	include	VBG
cord-267965-84sotgds	103	27	response	response	NN
cord-267965-84sotgds	103	28	to	to	IN
cord-267965-84sotgds	103	29	environmental	environmental	JJ
cord-267965-84sotgds	103	30	toxins	toxin	NNS
cord-267965-84sotgds	104	1	(	(	-LRB-
cord-267965-84sotgds	104	2	Venkatratnam	Venkatratnam	NNP
cord-267965-84sotgds	104	3	et	et	NNP
cord-267965-84sotgds	104	4	al	al	NNP
cord-267965-84sotgds	104	5	.	.	NNP
cord-267965-84sotgds	104	6	,	,	,
cord-267965-84sotgds	104	7	2017	2017	CD
cord-267965-84sotgds	104	8	)	)	-RRB-
cord-267965-84sotgds	104	9	,	,	,
cord-267965-84sotgds	104	10	nutrition	nutrition	NN
cord-267965-84sotgds	104	11	(	(	-LRB-
cord-267965-84sotgds	104	12	Schoenrock	Schoenrock	NNP
cord-267965-84sotgds	104	13	et	et	NNP
cord-267965-84sotgds	104	14	al	al	NNP
cord-267965-84sotgds	104	15	.	.	NNP
cord-267965-84sotgds	104	16	,	,	,
cord-267965-84sotgds	104	17	2018	2018	CD
cord-267965-84sotgds	104	18	)	)	-RRB-
cord-267965-84sotgds	104	19	,	,	,
cord-267965-84sotgds	104	20	body	body	NN
cord-267965-84sotgds	104	21	composition	composition	NN
cord-267965-84sotgds	104	22	(	(	-LRB-
cord-267965-84sotgds	104	23	Mathes	Mathes	NNP
cord-267965-84sotgds	104	24	et	et	NNP
cord-267965-84sotgds	104	25	al	al	NNP
cord-267965-84sotgds	104	26	.	.	NNP
cord-267965-84sotgds	104	27	,	,	,
cord-267965-84sotgds	104	28	2011	2011	CD
cord-267965-84sotgds	104	29	)	)	-RRB-
cord-267965-84sotgds	104	30	,	,	,
cord-267965-84sotgds	104	31	and	and	CC
cord-267965-84sotgds	104	32	immunity	immunity	NN
cord-267965-84sotgds	104	33	and	and	CC
cord-267965-84sotgds	104	34	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	104	35	(	(	-LRB-
cord-267965-84sotgds	104	36	discussed	discuss	VBN
cord-267965-84sotgds	104	37	further	further	RB
cord-267965-84sotgds	104	38	here	here	RB
cord-267965-84sotgds	104	39	)	)	-RRB-
cord-267965-84sotgds	104	40	.	.	.
cord-267965-84sotgds	105	1	Importantly	importantly	RB
cord-267965-84sotgds	105	2	,	,	,
cord-267965-84sotgds	105	3	these	these	DT
cord-267965-84sotgds	105	4	studies	study	NNS
cord-267965-84sotgds	105	5	have	have	VBP
cord-267965-84sotgds	105	6	highlighted	highlight	VBN
cord-267965-84sotgds	105	7	previously	previously	RB
cord-267965-84sotgds	105	8	uncharacterized	uncharacterized	JJ
cord-267965-84sotgds	105	9	phenotypic	phenotypic	JJ
cord-267965-84sotgds	105	10	diversity	diversity	NN
cord-267965-84sotgds	105	11	,	,	,
cord-267965-84sotgds	105	12	including	include	VBG
cord-267965-84sotgds	105	13	expansion	expansion	NN
cord-267965-84sotgds	105	14	of	of	IN
cord-267965-84sotgds	105	15	the	the	DT
cord-267965-84sotgds	105	16	phenotypic	phenotypic	JJ
cord-267965-84sotgds	105	17	range	range	NN
cord-267965-84sotgds	105	18	,	,	,
cord-267965-84sotgds	105	19	disassociation	disassociation	NN
cord-267965-84sotgds	105	20	of	of	IN
cord-267965-84sotgds	105	21	traits	trait	NNS
cord-267965-84sotgds	105	22	previously	previously	RB
cord-267965-84sotgds	105	23	thought	think	VBD
cord-267965-84sotgds	105	24	to	to	TO
cord-267965-84sotgds	105	25	be	be	VB
cord-267965-84sotgds	105	26	connected	connect	VBN
cord-267965-84sotgds	105	27	,	,	,
cord-267965-84sotgds	105	28	and	and	CC
cord-267965-84sotgds	105	29	identification	identification	NN
cord-267965-84sotgds	105	30	of	of	IN
cord-267965-84sotgds	105	31	completely	completely	RB
cord-267965-84sotgds	105	32	novel	novel	JJ
cord-267965-84sotgds	105	33	phenotypes	phenotype	NNS
cord-267965-84sotgds	105	34	(	(	-LRB-
cord-267965-84sotgds	105	35	Srivastava	Srivastava	NNP
cord-267965-84sotgds	105	36	et	et	NNP
cord-267965-84sotgds	105	37	al	al	NNP
cord-267965-84sotgds	105	38	.	.	NNP
cord-267965-84sotgds	105	39	,	,	,
cord-267965-84sotgds	105	40	2017	2017	CD
cord-267965-84sotgds	105	41	)	)	-RRB-
cord-267965-84sotgds	105	42	.	.	.
cord-267965-84sotgds	106	1	The	the	DT
cord-267965-84sotgds	106	2	CC	CC	NNP
cord-267965-84sotgds	106	3	is	be	VBZ
cord-267965-84sotgds	106	4	an	an	DT
cord-267965-84sotgds	106	5	especially	especially	RB
cord-267965-84sotgds	106	6	useful	useful	JJ
cord-267965-84sotgds	106	7	resource	resource	NN
cord-267965-84sotgds	106	8	for	for	IN
cord-267965-84sotgds	106	9	studying	study	VBG
cord-267965-84sotgds	106	10	the	the	DT
cord-267965-84sotgds	106	11	role	role	NN
cord-267965-84sotgds	106	12	of	of	IN
cord-267965-84sotgds	106	13	host	host	NN
cord-267965-84sotgds	106	14	genetics	genetics	NN
cord-267965-84sotgds	106	15	in	in	IN
cord-267965-84sotgds	106	16	hostpathogen	hostpathogen	NNP
cord-267965-84sotgds	106	17	interactions	interaction	NNS
cord-267965-84sotgds	106	18	because	because	IN
cord-267965-84sotgds	106	19	it	-PRON-	PRP
cord-267965-84sotgds	106	20	allows	allow	VBZ
cord-267965-84sotgds	106	21	for	for	IN
cord-267965-84sotgds	106	22	control	control	NN
cord-267965-84sotgds	106	23	of	of	IN
cord-267965-84sotgds	106	24	many	many	JJ
cord-267965-84sotgds	106	25	of	of	IN
cord-267965-84sotgds	106	26	the	the	DT
cord-267965-84sotgds	106	27	factors	factor	NNS
cord-267965-84sotgds	106	28	described	describe	VBN
cord-267965-84sotgds	106	29	above	above	IN
cord-267965-84sotgds	106	30	that	that	DT
cord-267965-84sotgds	106	31	confound	confound	VBP
cord-267965-84sotgds	106	32	infectious	infectious	JJ
cord-267965-84sotgds	106	33	disease	disease	NN
cord-267965-84sotgds	106	34	studies	study	NNS
cord-267965-84sotgds	106	35	in	in	IN
cord-267965-84sotgds	106	36	humans	human	NNS
cord-267965-84sotgds	106	37	.	.	.
cord-267965-84sotgds	107	1	Over	over	IN
cord-267965-84sotgds	107	2	the	the	DT
cord-267965-84sotgds	107	3	past	past	JJ
cord-267965-84sotgds	107	4	decade	decade	NN
cord-267965-84sotgds	107	5	,	,	,
cord-267965-84sotgds	107	6	a	a	DT
cord-267965-84sotgds	107	7	variety	variety	NN
cord-267965-84sotgds	107	8	of	of	IN
cord-267965-84sotgds	107	9	studies	study	NNS
cord-267965-84sotgds	107	10	utilizing	utilize	VBG
cord-267965-84sotgds	107	11	the	the	DT
cord-267965-84sotgds	107	12	CC	CC	NNP
cord-267965-84sotgds	107	13	,	,	,
cord-267965-84sotgds	107	14	including	include	VBG
cord-267965-84sotgds	107	15	non	non	AFX
cord-267965-84sotgds	107	16	-	-	JJ
cord-267965-84sotgds	107	17	fully	fully	RB
cord-267965-84sotgds	107	18	inbred	inbred	JJ
cord-267965-84sotgds	107	19	incipient	incipient	JJ
cord-267965-84sotgds	107	20	CC	cc	NN
cord-267965-84sotgds	107	21	lines	line	NNS
cord-267965-84sotgds	107	22	(	(	-LRB-
cord-267965-84sotgds	107	23	commonly	commonly	RB
cord-267965-84sotgds	107	24	termed	term	VBN
cord-267965-84sotgds	107	25	the	the	DT
cord-267965-84sotgds	107	26	pre	pre	JJ
cord-267965-84sotgds	107	27	-	-	NN
cord-267965-84sotgds	107	28	CC	CC	NNP
cord-267965-84sotgds	107	29	)	)	-RRB-
cord-267965-84sotgds	107	30	and	and	CC
cord-267965-84sotgds	107	31	derived	derive	VBN
cord-267965-84sotgds	107	32	CC	CC	NNP
cord-267965-84sotgds	107	33	populations	population	NNS
cord-267965-84sotgds	107	34	(	(	-LRB-
cord-267965-84sotgds	107	35	such	such	JJ
cord-267965-84sotgds	107	36	as	as	IN
cord-267965-84sotgds	107	37	CC	CC	NNP
cord-267965-84sotgds	107	38	-	-	HYPH
cord-267965-84sotgds	107	39	F1s	F1s	NNP
cord-267965-84sotgds	107	40	)	)	-RRB-
cord-267965-84sotgds	107	41	,	,	,
cord-267965-84sotgds	107	42	have	have	VBP
cord-267965-84sotgds	107	43	been	be	VBN
cord-267965-84sotgds	107	44	used	use	VBN
cord-267965-84sotgds	107	45	to	to	TO
cord-267965-84sotgds	107	46	probe	probe	VB
cord-267965-84sotgds	107	47	the	the	DT
cord-267965-84sotgds	107	48	role	role	NN
cord-267965-84sotgds	107	49	of	of	IN
cord-267965-84sotgds	107	50	host	host	NN
cord-267965-84sotgds	107	51	genetics	genetic	NNS
cord-267965-84sotgds	107	52	in	in	IN
cord-267965-84sotgds	107	53	the	the	DT
cord-267965-84sotgds	107	54	response	response	NN
cord-267965-84sotgds	107	55	to	to	IN
cord-267965-84sotgds	107	56	infectious	infectious	JJ
cord-267965-84sotgds	107	57	disease	disease	NN
cord-267965-84sotgds	107	58	.	.	.
cord-267965-84sotgds	108	1	Here	here	RB
cord-267965-84sotgds	108	2	we	-PRON-	PRP
cord-267965-84sotgds	108	3	will	will	MD
cord-267965-84sotgds	108	4	discuss	discuss	VB
cord-267965-84sotgds	108	5	the	the	DT
cord-267965-84sotgds	108	6	current	current	JJ
cord-267965-84sotgds	108	7	work	work	NN
cord-267965-84sotgds	108	8	in	in	IN
cord-267965-84sotgds	108	9	this	this	DT
cord-267965-84sotgds	108	10	field	field	NN
cord-267965-84sotgds	108	11	,	,	,
cord-267965-84sotgds	108	12	including	include	VBG
cord-267965-84sotgds	108	13	studies	study	NNS
cord-267965-84sotgds	108	14	focusing	focus	VBG
cord-267965-84sotgds	108	15	on	on	IN
cord-267965-84sotgds	108	16	phenotypic	phenotypic	JJ
cord-267965-84sotgds	108	17	characterization	characterization	NN
cord-267965-84sotgds	108	18	(	(	-LRB-
cord-267965-84sotgds	108	19	e.g.	e.g.	RB
cord-267965-84sotgds	108	20	,	,	,
cord-267965-84sotgds	108	21	model	model	NN
cord-267965-84sotgds	108	22	development	development	NN
cord-267965-84sotgds	108	23	and	and	CC
cord-267965-84sotgds	108	24	molecular	molecular	JJ
cord-267965-84sotgds	108	25	signatures	signature	NNS
cord-267965-84sotgds	108	26	of	of	IN
cord-267965-84sotgds	108	27	disease	disease	NN
cord-267965-84sotgds	108	28	response	response	NN
cord-267965-84sotgds	108	29	)	)	-RRB-
cord-267965-84sotgds	108	30	and	and	CC
cord-267965-84sotgds	108	31	genetic	genetic	JJ
cord-267965-84sotgds	108	32	mapping	mapping	NN
cord-267965-84sotgds	108	33	of	of	IN
cord-267965-84sotgds	108	34	disease	disease	NN
cord-267965-84sotgds	108	35	trait	trait	NN
cord-267965-84sotgds	108	36	-	-	HYPH
cord-267965-84sotgds	108	37	associated	associate	VBN
cord-267965-84sotgds	108	38	QTL	QTL	NNP
cord-267965-84sotgds	108	39	.	.	.
cord-267965-84sotgds	109	1	There	there	EX
cord-267965-84sotgds	109	2	is	be	VBZ
cord-267965-84sotgds	109	3	an	an	DT
cord-267965-84sotgds	109	4	ongoing	ongoing	JJ
cord-267965-84sotgds	109	5	debate	debate	NN
cord-267965-84sotgds	109	6	over	over	IN
cord-267965-84sotgds	109	7	the	the	DT
cord-267965-84sotgds	109	8	validity	validity	NN
cord-267965-84sotgds	109	9	of	of	IN
cord-267965-84sotgds	109	10	mouse	mouse	NN
cord-267965-84sotgds	109	11	models	model	NNS
cord-267965-84sotgds	109	12	in	in	IN
cord-267965-84sotgds	109	13	recapitulating	recapitulate	VBG
cord-267965-84sotgds	109	14	human	human	JJ
cord-267965-84sotgds	109	15	disease	disease	NN
cord-267965-84sotgds	109	16	(	(	-LRB-
cord-267965-84sotgds	109	17	Seok	Seok	NNP
cord-267965-84sotgds	109	18	et	et	NNP
cord-267965-84sotgds	109	19	al	al	NNP
cord-267965-84sotgds	109	20	.	.	NNP
cord-267965-84sotgds	109	21	,	,	,
cord-267965-84sotgds	109	22	2013	2013	CD
cord-267965-84sotgds	109	23	;	;	:
cord-267965-84sotgds	109	24	Takao	Takao	NNP
cord-267965-84sotgds	109	25	and	and	CC
cord-267965-84sotgds	109	26	Miyakawa	Miyakawa	NNP
cord-267965-84sotgds	109	27	,	,	,
cord-267965-84sotgds	109	28	2015	2015	CD
cord-267965-84sotgds	109	29	)	)	-RRB-
cord-267965-84sotgds	109	30	.	.	.
cord-267965-84sotgds	110	1	While	while	IN
cord-267965-84sotgds	110	2	the	the	DT
cord-267965-84sotgds	110	3	utility	utility	NN
cord-267965-84sotgds	110	4	of	of	IN
cord-267965-84sotgds	110	5	the	the	DT
cord-267965-84sotgds	110	6	mouse	mouse	NN
cord-267965-84sotgds	110	7	is	be	VBZ
cord-267965-84sotgds	110	8	undeniable	undeniable	JJ
cord-267965-84sotgds	110	9	in	in	IN
cord-267965-84sotgds	110	10	the	the	DT
cord-267965-84sotgds	110	11	infectious	infectious	JJ
cord-267965-84sotgds	110	12	disease	disease	NN
cord-267965-84sotgds	110	13	field	field	NN
cord-267965-84sotgds	110	14	,	,	,
cord-267965-84sotgds	110	15	it	-PRON-	PRP
cord-267965-84sotgds	110	16	is	be	VBZ
cord-267965-84sotgds	110	17	equally	equally	RB
cord-267965-84sotgds	110	18	true	true	JJ
cord-267965-84sotgds	110	19	that	that	IN
cord-267965-84sotgds	110	20	individual	individual	JJ
cord-267965-84sotgds	110	21	classical	classical	JJ
cord-267965-84sotgds	110	22	inbred	inbred	JJ
cord-267965-84sotgds	110	23	strains	strain	NNS
cord-267965-84sotgds	110	24	do	do	VBP
cord-267965-84sotgds	110	25	not	not	RB
cord-267965-84sotgds	110	26	fully	fully	RB
cord-267965-84sotgds	110	27	recapitulate	recapitulate	VB
cord-267965-84sotgds	110	28	human	human	JJ
cord-267965-84sotgds	110	29	disease	disease	NN
cord-267965-84sotgds	110	30	and	and	CC
cord-267965-84sotgds	110	31	most	most	JJS
cord-267965-84sotgds	110	32	models	model	NNS
cord-267965-84sotgds	110	33	recapitulate	recapitulate	VBP
cord-267965-84sotgds	110	34	only	only	RB
cord-267965-84sotgds	110	35	a	a	DT
cord-267965-84sotgds	110	36	portion	portion	NN
cord-267965-84sotgds	110	37	of	of	IN
cord-267965-84sotgds	110	38	the	the	DT
cord-267965-84sotgds	110	39	disease	disease	NN
cord-267965-84sotgds	110	40	phenotypes	phenotype	NNS
cord-267965-84sotgds	110	41	observed	observe	VBN
cord-267965-84sotgds	110	42	in	in	IN
cord-267965-84sotgds	110	43	humans	human	NNS
cord-267965-84sotgds	110	44	.	.	.
cord-267965-84sotgds	111	1	In	in	IN
cord-267965-84sotgds	111	2	an	an	DT
cord-267965-84sotgds	111	3	effort	effort	NN
cord-267965-84sotgds	111	4	to	to	TO
cord-267965-84sotgds	111	5	improve	improve	VB
cord-267965-84sotgds	111	6	model	model	NN
cord-267965-84sotgds	111	7	fidelity	fidelity	NN
cord-267965-84sotgds	111	8	to	to	IN
cord-267965-84sotgds	111	9	human	human	JJ
cord-267965-84sotgds	111	10	disease	disease	NN
cord-267965-84sotgds	111	11	,	,	,
cord-267965-84sotgds	111	12	a	a	DT
cord-267965-84sotgds	111	13	number	number	NN
cord-267965-84sotgds	111	14	of	of	IN
cord-267965-84sotgds	111	15	researchers	researcher	NNS
cord-267965-84sotgds	111	16	have	have	VBP
cord-267965-84sotgds	111	17	turned	turn	VBN
cord-267965-84sotgds	111	18	to	to	IN
cord-267965-84sotgds	111	19	the	the	DT
cord-267965-84sotgds	111	20	CC	CC	NNP
cord-267965-84sotgds	111	21	to	to	TO
cord-267965-84sotgds	111	22	develop	develop	VB
cord-267965-84sotgds	111	23	new	new	JJ
cord-267965-84sotgds	111	24	mouse	mouse	NN
cord-267965-84sotgds	111	25	models	model	NNS
cord-267965-84sotgds	111	26	.	.	.
cord-267965-84sotgds	112	1	Genetically	genetically	RB
cord-267965-84sotgds	112	2	diverse	diverse	JJ
cord-267965-84sotgds	112	3	CC	cc	NN
cord-267965-84sotgds	112	4	strains	strain	NNS
cord-267965-84sotgds	112	5	show	show	VBP
cord-267965-84sotgds	112	6	a	a	DT
cord-267965-84sotgds	112	7	range	range	NN
cord-267965-84sotgds	112	8	of	of	IN
cord-267965-84sotgds	112	9	responses	response	NNS
cord-267965-84sotgds	112	10	to	to	IN
cord-267965-84sotgds	112	11	pathogens	pathogen	NNS
cord-267965-84sotgds	112	12	,	,	,
cord-267965-84sotgds	112	13	from	from	IN
cord-267965-84sotgds	112	14	variation	variation	NN
cord-267965-84sotgds	112	15	in	in	IN
cord-267965-84sotgds	112	16	disease	disease	NN
cord-267965-84sotgds	112	17	severity	severity	NN
cord-267965-84sotgds	112	18	to	to	IN
cord-267965-84sotgds	112	19	completely	completely	RB
cord-267965-84sotgds	112	20	novel	novel	JJ
cord-267965-84sotgds	112	21	disease	disease	NN
cord-267965-84sotgds	112	22	phenotypes	phenotype	NNS
cord-267965-84sotgds	112	23	.	.	.
cord-267965-84sotgds	113	1	This	this	DT
cord-267965-84sotgds	113	2	phenotypic	phenotypic	JJ
cord-267965-84sotgds	113	3	variability	variability	NN
cord-267965-84sotgds	113	4	better	well	JJR
cord-267965-84sotgds	113	5	mimics	mimic	VBZ
cord-267965-84sotgds	113	6	the	the	DT
cord-267965-84sotgds	113	7	diversity	diversity	NN
cord-267965-84sotgds	113	8	of	of	IN
cord-267965-84sotgds	113	9	disease	disease	NN
cord-267965-84sotgds	113	10	presentation	presentation	NN
cord-267965-84sotgds	113	11	across	across	IN
cord-267965-84sotgds	113	12	the	the	DT
cord-267965-84sotgds	113	13	human	human	JJ
cord-267965-84sotgds	113	14	population	population	NN
cord-267965-84sotgds	113	15	,	,	,
cord-267965-84sotgds	113	16	thus	thus	RB
cord-267965-84sotgds	113	17	providing	provide	VBG
cord-267965-84sotgds	113	18	a	a	DT
cord-267965-84sotgds	113	19	more	more	RBR
cord-267965-84sotgds	113	20	comprehensive	comprehensive	JJ
cord-267965-84sotgds	113	21	platform	platform	NN
cord-267965-84sotgds	113	22	to	to	TO
cord-267965-84sotgds	113	23	develop	develop	VB
cord-267965-84sotgds	113	24	newer	new	JJR
cord-267965-84sotgds	113	25	,	,	,
cord-267965-84sotgds	113	26	more	more	RBR
cord-267965-84sotgds	113	27	representative	representative	JJ
cord-267965-84sotgds	113	28	mouse	mouse	NN
cord-267965-84sotgds	113	29	models	model	NNS
cord-267965-84sotgds	113	30	.	.	.
cord-267965-84sotgds	114	1	Ebola	Ebola	NNP
cord-267965-84sotgds	114	2	Virus	Virus	NNP
cord-267965-84sotgds	114	3	Ebola	Ebola	NNP
cord-267965-84sotgds	114	4	virus	virus	NN
cord-267965-84sotgds	114	5	(	(	-LRB-
cord-267965-84sotgds	114	6	EBOV	EBOV	NNP
cord-267965-84sotgds	114	7	)	)	-RRB-
cord-267965-84sotgds	114	8	causes	cause	VBZ
cord-267965-84sotgds	114	9	severe	severe	JJ
cord-267965-84sotgds	114	10	,	,	,
cord-267965-84sotgds	114	11	and	and	CC
cord-267965-84sotgds	114	12	often	often	RB
cord-267965-84sotgds	114	13	lethal	lethal	JJ
cord-267965-84sotgds	114	14	,	,	,
cord-267965-84sotgds	114	15	hemorrhagic	hemorrhagic	JJ
cord-267965-84sotgds	114	16	fever	fever	NN
cord-267965-84sotgds	114	17	in	in	IN
cord-267965-84sotgds	114	18	humans	human	NNS
cord-267965-84sotgds	114	19	.	.	.
cord-267965-84sotgds	115	1	While	while	IN
cord-267965-84sotgds	115	2	classical	classical	JJ
cord-267965-84sotgds	115	3	inbred	inbred	JJ
cord-267965-84sotgds	115	4	strains	strain	NNS
cord-267965-84sotgds	115	5	are	be	VBP
cord-267965-84sotgds	115	6	susceptible	susceptible	JJ
cord-267965-84sotgds	115	7	to	to	IN
cord-267965-84sotgds	115	8	mouse	mouse	NN
cord-267965-84sotgds	115	9	-	-	HYPH
cord-267965-84sotgds	115	10	adapted	adapt	VBN
cord-267965-84sotgds	115	11	EBOV	EBOV	NNP
cord-267965-84sotgds	116	1	(	(	-LRB-
cord-267965-84sotgds	116	2	MA	MA	NNP
cord-267965-84sotgds	116	3	-	-	HYPH
cord-267965-84sotgds	116	4	EBOV	EBOV	NNP
cord-267965-84sotgds	116	5	)	)	-RRB-
cord-267965-84sotgds	117	1	,	,	,
cord-267965-84sotgds	117	2	they	-PRON-	PRP
cord-267965-84sotgds	117	3	do	do	VBP
cord-267965-84sotgds	117	4	not	not	RB
cord-267965-84sotgds	117	5	display	display	VB
cord-267965-84sotgds	117	6	many	many	JJ
cord-267965-84sotgds	117	7	of	of	IN
cord-267965-84sotgds	117	8	the	the	DT
cord-267965-84sotgds	117	9	characteristic	characteristic	JJ
cord-267965-84sotgds	117	10	symptoms	symptom	NNS
cord-267965-84sotgds	117	11	observed	observe	VBN
cord-267965-84sotgds	117	12	in	in	IN
cord-267965-84sotgds	117	13	severe	severe	JJ
cord-267965-84sotgds	117	14	human	human	JJ
cord-267965-84sotgds	117	15	cases	case	NNS
cord-267965-84sotgds	117	16	such	such	JJ
cord-267965-84sotgds	117	17	as	as	IN
cord-267965-84sotgds	117	18	coagulopathy	coagulopathy	NN
cord-267965-84sotgds	117	19	,	,	,
cord-267965-84sotgds	117	20	hemorrhagic	hemorrhagic	JJ
cord-267965-84sotgds	117	21	manifestations	manifestation	NNS
cord-267965-84sotgds	117	22	,	,	,
cord-267965-84sotgds	117	23	and	and	CC
cord-267965-84sotgds	117	24	rash	rash	JJ
cord-267965-84sotgds	118	1	(	(	-LRB-
cord-267965-84sotgds	118	2	St	St	NNP
cord-267965-84sotgds	118	3	Claire	Claire	NNP
cord-267965-84sotgds	118	4	et	et	NNP
cord-267965-84sotgds	118	5	al	al	NNP
cord-267965-84sotgds	118	6	.	.	NNP
cord-267965-84sotgds	118	7	,	,	,
cord-267965-84sotgds	118	8	2017	2017	CD
cord-267965-84sotgds	118	9	)	)	-RRB-
cord-267965-84sotgds	118	10	.	.	.
cord-267965-84sotgds	119	1	Rasmussen	Rasmussen	NNP
cord-267965-84sotgds	119	2	et	et	NNP
cord-267965-84sotgds	119	3	al	al	NNP
cord-267965-84sotgds	119	4	.	.	.
cord-267965-84sotgds	120	1	infected	infect	VBD
cord-267965-84sotgds	120	2	a	a	DT
cord-267965-84sotgds	120	3	panel	panel	NN
cord-267965-84sotgds	120	4	of	of	IN
cord-267965-84sotgds	120	5	F1	F1	NNP
cord-267965-84sotgds	120	6	crosses	crosse	NNS
cord-267965-84sotgds	120	7	between	between	IN
cord-267965-84sotgds	120	8	CC	cc	NN
cord-267965-84sotgds	120	9	strains	strain	NNS
cord-267965-84sotgds	120	10	(	(	-LRB-
cord-267965-84sotgds	120	11	CC	cc	NN
cord-267965-84sotgds	120	12	-	-	HYPH
cord-267965-84sotgds	120	13	F1s	F1s	NNP
cord-267965-84sotgds	120	14	)	)	-RRB-
cord-267965-84sotgds	120	15	following	follow	VBG
cord-267965-84sotgds	120	16	an	an	DT
cord-267965-84sotgds	120	17	initial	initial	JJ
cord-267965-84sotgds	120	18	assessment	assessment	NN
cord-267965-84sotgds	120	19	in	in	IN
cord-267965-84sotgds	120	20	founder	founder	NN
cord-267965-84sotgds	120	21	strains	strain	NNS
cord-267965-84sotgds	120	22	(	(	-LRB-
cord-267965-84sotgds	120	23	Rasmussen	Rasmussen	NNP
cord-267965-84sotgds	120	24	et	et	NNP
cord-267965-84sotgds	120	25	al	al	NNP
cord-267965-84sotgds	120	26	.	.	NNP
cord-267965-84sotgds	120	27	,	,	,
cord-267965-84sotgds	120	28	2014	2014	CD
cord-267965-84sotgds	120	29	)	)	-RRB-
cord-267965-84sotgds	120	30	.	.	.
cord-267965-84sotgds	121	1	They	-PRON-	PRP
cord-267965-84sotgds	121	2	observed	observe	VBD
cord-267965-84sotgds	121	3	significant	significant	JJ
cord-267965-84sotgds	121	4	phenotypic	phenotypic	JJ
cord-267965-84sotgds	121	5	variation	variation	NN
cord-267965-84sotgds	121	6	following	follow	VBG
cord-267965-84sotgds	121	7	MA	MA	NNP
cord-267965-84sotgds	121	8	-	-	HYPH
cord-267965-84sotgds	121	9	EBOV	EBOV	NNP
cord-267965-84sotgds	121	10	infection	infection	NN
cord-267965-84sotgds	121	11	,	,	,
cord-267965-84sotgds	121	12	from	from	IN
cord-267965-84sotgds	121	13	high	high	JJ
cord-267965-84sotgds	121	14	resistance	resistance	NN
cord-267965-84sotgds	121	15	to	to	TO
cord-267965-84sotgds	121	16	complete	complete	VB
cord-267965-84sotgds	121	17	lethality	lethality	NN
cord-267965-84sotgds	121	18	,	,	,
cord-267965-84sotgds	121	19	and	and	CC
cord-267965-84sotgds	121	20	covering	cover	VBG
cord-267965-84sotgds	121	21	a	a	DT
cord-267965-84sotgds	121	22	spectrum	spectrum	NN
cord-267965-84sotgds	121	23	of	of	IN
cord-267965-84sotgds	121	24	different	different	JJ
cord-267965-84sotgds	121	25	pathologies	pathology	NNS
cord-267965-84sotgds	121	26	similar	similar	JJ
cord-267965-84sotgds	121	27	to	to	IN
cord-267965-84sotgds	121	28	the	the	DT
cord-267965-84sotgds	121	29	range	range	NN
cord-267965-84sotgds	121	30	of	of	IN
cord-267965-84sotgds	121	31	clinical	clinical	JJ
cord-267965-84sotgds	121	32	disease	disease	NN
cord-267965-84sotgds	121	33	observed	observe	VBN
cord-267965-84sotgds	121	34	in	in	IN
cord-267965-84sotgds	121	35	humans	human	NNS
cord-267965-84sotgds	121	36	.	.	.
cord-267965-84sotgds	122	1	Importantly	importantly	RB
cord-267965-84sotgds	122	2	,	,	,
cord-267965-84sotgds	122	3	some	some	DT
cord-267965-84sotgds	122	4	strains	strain	NNS
cord-267965-84sotgds	122	5	presented	present	VBN
cord-267965-84sotgds	122	6	with	with	IN
cord-267965-84sotgds	122	7	severe	severe	JJ
cord-267965-84sotgds	122	8	hemorrhagic	hemorrhagic	JJ
cord-267965-84sotgds	122	9	disease	disease	NN
cord-267965-84sotgds	122	10	and	and	CC
cord-267965-84sotgds	122	11	liver	liver	NN
cord-267965-84sotgds	122	12	damage	damage	NN
cord-267965-84sotgds	122	13	,	,	,
cord-267965-84sotgds	122	14	consistent	consistent	JJ
cord-267965-84sotgds	122	15	with	with	IN
cord-267965-84sotgds	122	16	human	human	JJ
cord-267965-84sotgds	122	17	EBOV	EBOV	NNP
cord-267965-84sotgds	122	18	disease	disease	NN
cord-267965-84sotgds	122	19	.	.	.
cord-267965-84sotgds	123	1	Follow	follow	VB
cord-267965-84sotgds	123	2	-	-	HYPH
cord-267965-84sotgds	123	3	up	up	NN
cord-267965-84sotgds	123	4	studies	study	NNS
cord-267965-84sotgds	123	5	with	with	IN
cord-267965-84sotgds	123	6	representative	representative	JJ
cord-267965-84sotgds	123	7	susceptible	susceptible	JJ
cord-267965-84sotgds	123	8	and	and	CC
cord-267965-84sotgds	123	9	resistant	resistant	JJ
cord-267965-84sotgds	123	10	strains	strain	NNS
cord-267965-84sotgds	123	11	found	find	VBD
cord-267965-84sotgds	123	12	differential	differential	JJ
cord-267965-84sotgds	123	13	transcriptional	transcriptional	JJ
cord-267965-84sotgds	123	14	responses	response	NNS
cord-267965-84sotgds	123	15	,	,	,
cord-267965-84sotgds	123	16	highlighting	highlight	VBG
cord-267965-84sotgds	123	17	the	the	DT
cord-267965-84sotgds	123	18	central	central	JJ
cord-267965-84sotgds	123	19	transcriptional	transcriptional	JJ
cord-267965-84sotgds	123	20	regulatory	regulatory	JJ
cord-267965-84sotgds	123	21	gene	gene	NN
cord-267965-84sotgds	123	22	Tek	Tek	NNP
cord-267965-84sotgds	123	23	,	,	,
cord-267965-84sotgds	123	24	for	for	IN
cord-267965-84sotgds	123	25	which	which	WDT
cord-267965-84sotgds	123	26	haplotypes	haplotype	NNS
cord-267965-84sotgds	123	27	across	across	IN
cord-267965-84sotgds	123	28	these	these	DT
cord-267965-84sotgds	123	29	CC	CC	NNP
cord-267965-84sotgds	123	30	-	-	HYPH
cord-267965-84sotgds	123	31	F1s	F1s	NNP
cord-267965-84sotgds	123	32	correlated	correlate	VBN
cord-267965-84sotgds	123	33	with	with	IN
cord-267965-84sotgds	123	34	weight	weight	NN
cord-267965-84sotgds	123	35	loss	loss	NN
cord-267965-84sotgds	123	36	and	and	CC
cord-267965-84sotgds	123	37	mortality	mortality	NN
cord-267965-84sotgds	123	38	following	follow	VBG
cord-267965-84sotgds	123	39	MA	MA	NNP
cord-267965-84sotgds	123	40	-	-	HYPH
cord-267965-84sotgds	123	41	EBOV	EBOV	NNP
cord-267965-84sotgds	123	42	infection	infection	NN
cord-267965-84sotgds	123	43	.	.	.
cord-267965-84sotgds	124	1	West	West	NNP
cord-267965-84sotgds	124	2	Nile	Nile	NNP
cord-267965-84sotgds	124	3	virus	virus	NN
cord-267965-84sotgds	124	4	(	(	-LRB-
cord-267965-84sotgds	124	5	WNV	WNV	NNP
cord-267965-84sotgds	124	6	)	)	-RRB-
cord-267965-84sotgds	124	7	,	,	,
cord-267965-84sotgds	124	8	a	a	DT
cord-267965-84sotgds	124	9	neuroinvasive	neuroinvasive	JJ
cord-267965-84sotgds	124	10	flavivirus	flavivirus	NN
cord-267965-84sotgds	124	11	,	,	,
cord-267965-84sotgds	124	12	induces	induce	VBZ
cord-267965-84sotgds	124	13	a	a	DT
cord-267965-84sotgds	124	14	diverse	diverse	JJ
cord-267965-84sotgds	124	15	spectrum	spectrum	NN
cord-267965-84sotgds	124	16	of	of	IN
cord-267965-84sotgds	124	17	immune	immune	JJ
cord-267965-84sotgds	124	18	responses	response	NNS
cord-267965-84sotgds	124	19	and	and	CC
cord-267965-84sotgds	124	20	clinical	clinical	JJ
cord-267965-84sotgds	124	21	outcomes	outcome	NNS
cord-267965-84sotgds	124	22	in	in	IN
cord-267965-84sotgds	124	23	humans	human	NNS
cord-267965-84sotgds	124	24	that	that	IN
cord-267965-84sotgds	124	25	classical	classical	JJ
cord-267965-84sotgds	124	26	mouse	mouse	NN
cord-267965-84sotgds	124	27	models	model	NNS
cord-267965-84sotgds	124	28	do	do	VBP
cord-267965-84sotgds	124	29	not	not	RB
cord-267965-84sotgds	124	30	fully	fully	RB
cord-267965-84sotgds	124	31	recapitulate	recapitulate	VB
cord-267965-84sotgds	124	32	(	(	-LRB-
cord-267965-84sotgds	124	33	Graham	Graham	NNP
cord-267965-84sotgds	124	34	et	et	NNP
cord-267965-84sotgds	124	35	al	al	NNP
cord-267965-84sotgds	124	36	.	.	NNP
cord-267965-84sotgds	124	37	,	,	,
cord-267965-84sotgds	124	38	2015	2015	CD
cord-267965-84sotgds	124	39	)	)	-RRB-
cord-267965-84sotgds	124	40	.	.	.
cord-267965-84sotgds	125	1	Graham	Graham	NNP
cord-267965-84sotgds	125	2	et	et	NNP
cord-267965-84sotgds	125	3	al	al	NNP
cord-267965-84sotgds	125	4	.	.	.
cord-267965-84sotgds	126	1	assessed	assess	VBN
cord-267965-84sotgds	126	2	WNV	WNV	NNP
cord-267965-84sotgds	126	3	susceptibility	susceptibility	NN
cord-267965-84sotgds	126	4	in	in	IN
cord-267965-84sotgds	126	5	a	a	DT
cord-267965-84sotgds	126	6	panel	panel	NN
cord-267965-84sotgds	126	7	of	of	IN
cord-267965-84sotgds	126	8	CC	CC	NNP
cord-267965-84sotgds	126	9	-	-	HYPH
cord-267965-84sotgds	126	10	F1	F1	NNP
cord-267965-84sotgds	126	11	crosses	crosse	NNS
cord-267965-84sotgds	126	12	that	that	WDT
cord-267965-84sotgds	126	13	were	be	VBD
cord-267965-84sotgds	126	14	heterozygous	heterozygous	JJ
cord-267965-84sotgds	126	15	for	for	IN
cord-267965-84sotgds	126	16	the	the	DT
cord-267965-84sotgds	126	17	H-2b	H-2b	NNP
cord-267965-84sotgds	126	18	MHC	MHC	NNP
cord-267965-84sotgds	126	19	haplotype	haplotype	NN
cord-267965-84sotgds	126	20	,	,	,
cord-267965-84sotgds	126	21	which	which	WDT
cord-267965-84sotgds	126	22	allowed	allow	VBD
cord-267965-84sotgds	126	23	quantification	quantification	NN
cord-267965-84sotgds	126	24	of	of	IN
cord-267965-84sotgds	126	25	WNV	WNV	NNP
cord-267965-84sotgds	126	26	-	-	HYPH
cord-267965-84sotgds	126	27	specific	specific	JJ
cord-267965-84sotgds	126	28	T	t	NN
cord-267965-84sotgds	126	29	cells	cell	NNS
cord-267965-84sotgds	126	30	with	with	IN
cord-267965-84sotgds	126	31	the	the	DT
cord-267965-84sotgds	126	32	same	same	JJ
cord-267965-84sotgds	126	33	MHC	MHC	NNP
cord-267965-84sotgds	126	34	tetramer	tetramer	NN
cord-267965-84sotgds	126	35	.	.	.
cord-267965-84sotgds	127	1	WNV	WNV	NNP
cord-267965-84sotgds	127	2	outcome	outcome	NN
cord-267965-84sotgds	127	3	ranged	range	VBD
cord-267965-84sotgds	127	4	from	from	IN
cord-267965-84sotgds	127	5	highly	highly	RB
cord-267965-84sotgds	127	6	resistant	resistant	JJ
cord-267965-84sotgds	127	7	to	to	IN
cord-267965-84sotgds	127	8	highly	highly	RB
cord-267965-84sotgds	127	9	susceptible	susceptible	JJ
cord-267965-84sotgds	127	10	,	,	,
cord-267965-84sotgds	127	11	including	include	VBG
cord-267965-84sotgds	127	12	a	a	DT
cord-267965-84sotgds	127	13	novel	novel	JJ
cord-267965-84sotgds	127	14	outcome	outcome	NN
cord-267965-84sotgds	127	15	group	group	NN
cord-267965-84sotgds	127	16	in	in	IN
cord-267965-84sotgds	127	17	which	which	WDT
cord-267965-84sotgds	127	18	mice	mouse	NNS
cord-267965-84sotgds	127	19	were	be	VBD
cord-267965-84sotgds	127	20	outwardly	outwardly	RB
cord-267965-84sotgds	127	21	asymptomatic	asymptomatic	JJ
cord-267965-84sotgds	127	22	despite	despite	IN
cord-267965-84sotgds	127	23	higher	high	JJR
cord-267965-84sotgds	127	24	viral	viral	JJ
cord-267965-84sotgds	127	25	titers	titer	NNS
cord-267965-84sotgds	127	26	and	and	CC
cord-267965-84sotgds	127	27	immunopathology	immunopathology	NN
cord-267965-84sotgds	127	28	in	in	IN
cord-267965-84sotgds	127	29	the	the	DT
cord-267965-84sotgds	127	30	brain	brain	NN
cord-267965-84sotgds	127	31	.	.	.
cord-267965-84sotgds	128	1	Graham	Graham	NNP
cord-267965-84sotgds	128	2	et	et	NNP
cord-267965-84sotgds	128	3	al	al	NNP
cord-267965-84sotgds	128	4	.	.	NNP
cord-267965-84sotgds	128	5	followed	follow	VBD
cord-267965-84sotgds	128	6	up	up	RP
cord-267965-84sotgds	128	7	on	on	IN
cord-267965-84sotgds	128	8	one	one	CD
cord-267965-84sotgds	128	9	unique	unique	JJ
cord-267965-84sotgds	128	10	CC	CC	NNP
cord-267965-84sotgds	128	11	-	-	HYPH
cord-267965-84sotgds	128	12	F1	F1	NNP
cord-267965-84sotgds	128	13	(	(	-LRB-
cord-267965-84sotgds	128	14	(	(	-LRB-
cord-267965-84sotgds	128	15	CC032/	CC032/	NNP
cord-267965-84sotgds	128	16	GeniUnc	GeniUnc	NNP
cord-267965-84sotgds	128	17	3	3	CD
cord-267965-84sotgds	128	18	CC013	CC013	NNP
cord-267965-84sotgds	128	19	/	/	SYM
cord-267965-84sotgds	128	20	GeniUnc)-F1	GeniUnc)-F1	NNP
cord-267965-84sotgds	128	21	)	)	-RRB-
cord-267965-84sotgds	128	22	,	,	,
cord-267965-84sotgds	128	23	in	in	IN
cord-267965-84sotgds	128	24	which	which	WDT
cord-267965-84sotgds	128	25	half	half	NN
cord-267965-84sotgds	128	26	of	of	IN
cord-267965-84sotgds	128	27	the	the	DT
cord-267965-84sotgds	128	28	mice	mouse	NNS
cord-267965-84sotgds	128	29	that	that	WDT
cord-267965-84sotgds	128	30	survived	survive	VBD
cord-267965-84sotgds	128	31	infection	infection	NN
cord-267965-84sotgds	128	32	displayed	display	VBD
cord-267965-84sotgds	128	33	sustained	sustained	JJ
cord-267965-84sotgds	128	34	weight	weight	NN
cord-267965-84sotgds	128	35	loss	loss	NN
cord-267965-84sotgds	128	36	and	and	CC
cord-267965-84sotgds	128	37	persistent	persistent	JJ
cord-267965-84sotgds	128	38	viral	viral	JJ
cord-267965-84sotgds	128	39	loads	load	NNS
cord-267965-84sotgds	128	40	in	in	IN
cord-267965-84sotgds	128	41	the	the	DT
cord-267965-84sotgds	128	42	CNS	CNS	NNP
cord-267965-84sotgds	128	43	.	.	.
cord-267965-84sotgds	129	1	They	-PRON-	PRP
cord-267965-84sotgds	129	2	found	find	VBD
cord-267965-84sotgds	129	3	that	that	IN
cord-267965-84sotgds	129	4	these	these	DT
cord-267965-84sotgds	129	5	mice	mouse	NNS
cord-267965-84sotgds	129	6	exhibited	exhibit	VBD
cord-267965-84sotgds	129	7	a	a	DT
cord-267965-84sotgds	129	8	rapid	rapid	JJ
cord-267965-84sotgds	129	9	early	early	JJ
cord-267965-84sotgds	129	10	innate	innate	JJ
cord-267965-84sotgds	129	11	inflammatory	inflammatory	JJ
cord-267965-84sotgds	129	12	response	response	NN
cord-267965-84sotgds	129	13	characterized	characterize	VBN
cord-267965-84sotgds	129	14	by	by	IN
cord-267965-84sotgds	129	15	increased	increase	VBN
cord-267965-84sotgds	129	16	early	early	JJ
cord-267965-84sotgds	129	17	expression	expression	NN
cord-267965-84sotgds	129	18	of	of	IN
cord-267965-84sotgds	129	19	IFN	IFN	NNP
cord-267965-84sotgds	129	20	-	-	HYPH
cord-267965-84sotgds	129	21	b	b	NNP
cord-267965-84sotgds	129	22	and	and	CC
cord-267965-84sotgds	129	23	the	the	DT
cord-267965-84sotgds	129	24	interferonstimulated	interferonstimulate	VBN
cord-267965-84sotgds	129	25	gene	gene	NN
cord-267965-84sotgds	129	26	IFN1	IFN1	NNP
cord-267965-84sotgds	129	27	,	,	,
cord-267965-84sotgds	129	28	as	as	RB
cord-267965-84sotgds	129	29	well	well	RB
cord-267965-84sotgds	129	30	as	as	IN
cord-267965-84sotgds	129	31	high	high	JJ
cord-267965-84sotgds	129	32	early	early	JJ
cord-267965-84sotgds	129	33	viral	viral	JJ
cord-267965-84sotgds	129	34	titers	titer	NNS
cord-267965-84sotgds	129	35	and	and	CC
cord-267965-84sotgds	129	36	the	the	DT
cord-267965-84sotgds	129	37	ability	ability	NN
cord-267965-84sotgds	129	38	to	to	TO
cord-267965-84sotgds	129	39	control	control	VB
cord-267965-84sotgds	129	40	,	,	,
cord-267965-84sotgds	129	41	but	but	CC
cord-267965-84sotgds	129	42	not	not	RB
cord-267965-84sotgds	129	43	clear	clear	JJ
cord-267965-84sotgds	129	44	,	,	,
cord-267965-84sotgds	129	45	viral	viral	JJ
cord-267965-84sotgds	129	46	replication	replication	NN
cord-267965-84sotgds	129	47	in	in	IN
cord-267965-84sotgds	129	48	the	the	DT
cord-267965-84sotgds	129	49	CNS	CNS	NNP
cord-267965-84sotgds	129	50	Figure	Figure	NNP
cord-267965-84sotgds	129	51	1	1	CD
cord-267965-84sotgds	129	52	.	.	.
cord-267965-84sotgds	130	1	Representative	Representative	NNP
cord-267965-84sotgds	130	2	CC	CC	NNP
cord-267965-84sotgds	130	3	Funnels	funnel	NNS
cord-267965-84sotgds	130	4	CC	CC	NNP
cord-267965-84sotgds	130	5	founders	founder	NNS
cord-267965-84sotgds	130	6	were	be	VBD
cord-267965-84sotgds	130	7	bred	breed	VBN
cord-267965-84sotgds	130	8	in	in	IN
cord-267965-84sotgds	130	9	funnel	funnel	NN
cord-267965-84sotgds	130	10	breeding	breeding	NN
cord-267965-84sotgds	130	11	schemes	scheme	NNS
cord-267965-84sotgds	130	12	to	to	TO
cord-267965-84sotgds	130	13	produce	produce	VB
cord-267965-84sotgds	130	14	progeny	progeny	NNS
cord-267965-84sotgds	130	15	with	with	IN
cord-267965-84sotgds	130	16	genetic	genetic	JJ
cord-267965-84sotgds	130	17	contributions	contribution	NNS
cord-267965-84sotgds	130	18	from	from	IN
cord-267965-84sotgds	130	19	each	each	DT
cord-267965-84sotgds	130	20	of	of	IN
cord-267965-84sotgds	130	21	the	the	DT
cord-267965-84sotgds	130	22	eight	eight	CD
cord-267965-84sotgds	130	23	founders	founder	NNS
cord-267965-84sotgds	130	24	,	,	,
cord-267965-84sotgds	130	25	at	at	IN
cord-267965-84sotgds	130	26	which	which	WDT
cord-267965-84sotgds	130	27	point	point	NN
cord-267965-84sotgds	130	28	they	-PRON-	PRP
cord-267965-84sotgds	130	29	were	be	VBD
cord-267965-84sotgds	130	30	inbred	inbreed	VBN
cord-267965-84sotgds	130	31	for	for	IN
cord-267965-84sotgds	130	32	generations	generation	NNS
cord-267965-84sotgds	130	33	until	until	IN
cord-267965-84sotgds	130	34	reaching	reach	VBG
cord-267965-84sotgds	130	35	near	near	IN
cord-267965-84sotgds	130	36	homozygosity	homozygosity	NN
cord-267965-84sotgds	130	37	.	.	.
cord-267965-84sotgds	131	1	Many	many	JJ
cord-267965-84sotgds	131	2	different	different	JJ
cord-267965-84sotgds	131	3	funnels	funnel	NNS
cord-267965-84sotgds	131	4	were	be	VBD
cord-267965-84sotgds	131	5	set	set	VBN
cord-267965-84sotgds	131	6	up	up	RP
cord-267965-84sotgds	131	7	,	,	,
cord-267965-84sotgds	131	8	each	each	DT
cord-267965-84sotgds	131	9	to	to	TO
cord-267965-84sotgds	131	10	produce	produce	VB
cord-267965-84sotgds	131	11	a	a	DT
cord-267965-84sotgds	131	12	unique	unique	JJ
cord-267965-84sotgds	131	13	CC	cc	NN
cord-267965-84sotgds	131	14	RI	RI	NNP
cord-267965-84sotgds	131	15	line	line	NN
cord-267965-84sotgds	131	16	.	.	.
cord-267965-84sotgds	132	1	(	(	-LRB-
cord-267965-84sotgds	132	2	Graham	Graham	NNP
cord-267965-84sotgds	132	3	et	et	NNP
cord-267965-84sotgds	132	4	al	al	NNP
cord-267965-84sotgds	132	5	.	.	NNP
cord-267965-84sotgds	132	6	,	,	,
cord-267965-84sotgds	132	7	2016	2016	CD
cord-267965-84sotgds	132	8	)	)	-RRB-
cord-267965-84sotgds	132	9	.	.	.
cord-267965-84sotgds	133	1	Additionally	additionally	RB
cord-267965-84sotgds	133	2	,	,	,
cord-267965-84sotgds	133	3	(	(	-LRB-
cord-267965-84sotgds	133	4	CC032	CC032	NNP
cord-267965-84sotgds	133	5	/	/	SYM
cord-267965-84sotgds	133	6	GeniUnc	GeniUnc	NNP
cord-267965-84sotgds	133	7	3	3	CD
cord-267965-84sotgds	133	8	CC013/	CC013/	NNP
cord-267965-84sotgds	133	9	GeniUnc)-F1	geniunc)-f1	CD
cord-267965-84sotgds	133	10	mice	mouse	NNS
cord-267965-84sotgds	133	11	had	have	VBD
cord-267965-84sotgds	133	12	a	a	DT
cord-267965-84sotgds	133	13	unique	unique	JJ
cord-267965-84sotgds	133	14	immunoregulatory	immunoregulatory	JJ
cord-267965-84sotgds	133	15	signature	signature	NN
cord-267965-84sotgds	133	16	,	,	,
cord-267965-84sotgds	133	17	with	with	IN
cord-267965-84sotgds	133	18	a	a	DT
cord-267965-84sotgds	133	19	high	high	JJ
cord-267965-84sotgds	133	20	number	number	NN
cord-267965-84sotgds	133	21	of	of	IN
cord-267965-84sotgds	133	22	T	T	NNP
cord-267965-84sotgds	133	23	regulatory	regulatory	JJ
cord-267965-84sotgds	133	24	cells	cell	NNS
cord-267965-84sotgds	133	25	in	in	IN
cord-267965-84sotgds	133	26	both	both	CC
cord-267965-84sotgds	133	27	infected	infected	JJ
cord-267965-84sotgds	133	28	and	and	CC
cord-267965-84sotgds	133	29	uninfected	uninfected	JJ
cord-267965-84sotgds	133	30	animals	animal	NNS
cord-267965-84sotgds	133	31	and	and	CC
cord-267965-84sotgds	133	32	a	a	DT
cord-267965-84sotgds	133	33	distinctive	distinctive	JJ
cord-267965-84sotgds	133	34	post	post	JJ
cord-267965-84sotgds	133	35	-	-	JJ
cord-267965-84sotgds	133	36	infection	infection	JJ
cord-267965-84sotgds	133	37	gene	gene	NN
cord-267965-84sotgds	133	38	expression	expression	NN
cord-267965-84sotgds	133	39	profile	profile	NN
cord-267965-84sotgds	133	40	that	that	WDT
cord-267965-84sotgds	133	41	indicated	indicate	VBD
cord-267965-84sotgds	133	42	reduced	reduce	VBN
cord-267965-84sotgds	133	43	cytolytic	cytolytic	JJ
cord-267965-84sotgds	133	44	ability	ability	NN
cord-267965-84sotgds	133	45	.	.	.
cord-267965-84sotgds	134	1	The	the	DT
cord-267965-84sotgds	134	2	initial	initial	JJ
cord-267965-84sotgds	134	3	Graham	Graham	NNP
cord-267965-84sotgds	134	4	et	et	FW
cord-267965-84sotgds	134	5	al	al	NNP
cord-267965-84sotgds	134	6	.	.	.
cord-267965-84sotgds	134	7	study	study	NNP
cord-267965-84sotgds	134	8	(	(	-LRB-
cord-267965-84sotgds	134	9	Graham	Graham	NNP
cord-267965-84sotgds	134	10	et	et	NNP
cord-267965-84sotgds	134	11	al	al	NNP
cord-267965-84sotgds	134	12	.	.	NNP
cord-267965-84sotgds	134	13	,	,	,
cord-267965-84sotgds	134	14	2015	2015	CD
cord-267965-84sotgds	134	15	)	)	-RRB-
cord-267965-84sotgds	134	16	found	find	VBD
cord-267965-84sotgds	134	17	that	that	IN
cord-267965-84sotgds	134	18	WNV	WNV	NNP
cord-267965-84sotgds	134	19	response	response	NN
cord-267965-84sotgds	134	20	largely	largely	RB
cord-267965-84sotgds	134	21	tracked	track	VBD
cord-267965-84sotgds	134	22	with	with	IN
cord-267965-84sotgds	134	23	the	the	DT
cord-267965-84sotgds	134	24	haplotype	haplotype	NN
cord-267965-84sotgds	134	25	of	of	IN
cord-267965-84sotgds	134	26	Oas1b	Oas1b	NNP
cord-267965-84sotgds	134	27	,	,	,
cord-267965-84sotgds	134	28	a	a	DT
cord-267965-84sotgds	134	29	known	know	VBN
cord-267965-84sotgds	134	30	flavivirus	flavivirus	JJ
cord-267965-84sotgds	134	31	resistance	resistance	NN
cord-267965-84sotgds	134	32	gene	gene	NN
cord-267965-84sotgds	134	33	,	,	,
cord-267965-84sotgds	134	34	although	although	IN
cord-267965-84sotgds	134	35	there	there	EX
cord-267965-84sotgds	134	36	was	be	VBD
cord-267965-84sotgds	134	37	still	still	RB
cord-267965-84sotgds	134	38	considerable	considerable	JJ
cord-267965-84sotgds	134	39	disease	disease	NN
cord-267965-84sotgds	134	40	variation	variation	NN
cord-267965-84sotgds	134	41	within	within	IN
cord-267965-84sotgds	134	42	Oas1b	Oas1b	NNP
cord-267965-84sotgds	134	43	haplotype	haplotype	NN
cord-267965-84sotgds	134	44	groups	group	NNS
cord-267965-84sotgds	134	45	.	.	.
cord-267965-84sotgds	135	1	Green	Green	NNP
cord-267965-84sotgds	135	2	et	et	FW
cord-267965-84sotgds	135	3	al	al	NNP
cord-267965-84sotgds	135	4	.	.	.
cord-267965-84sotgds	136	1	continued	continue	VBD
cord-267965-84sotgds	136	2	to	to	TO
cord-267965-84sotgds	136	3	dissect	dissect	VB
cord-267965-84sotgds	136	4	the	the	DT
cord-267965-84sotgds	136	5	impact	impact	NN
cord-267965-84sotgds	136	6	of	of	IN
cord-267965-84sotgds	136	7	Oas1b	Oas1b	NNP
cord-267965-84sotgds	136	8	on	on	IN
cord-267965-84sotgds	136	9	the	the	DT
cord-267965-84sotgds	136	10	innate	innate	JJ
cord-267965-84sotgds	136	11	immune	immune	JJ
cord-267965-84sotgds	136	12	transcriptional	transcriptional	JJ
cord-267965-84sotgds	136	13	landscape	landscape	NN
cord-267965-84sotgds	136	14	following	follow	VBG
cord-267965-84sotgds	136	15	WNV	WNV	NNP
cord-267965-84sotgds	136	16	infection	infection	NN
cord-267965-84sotgds	137	1	(	(	-LRB-
cord-267965-84sotgds	137	2	Green	Green	NNP
cord-267965-84sotgds	137	3	et	et	FW
cord-267965-84sotgds	137	4	al	al	NNP
cord-267965-84sotgds	137	5	.	.	NNP
cord-267965-84sotgds	137	6	,	,	,
cord-267965-84sotgds	137	7	2017	2017	CD
cord-267965-84sotgds	137	8	)	)	-RRB-
cord-267965-84sotgds	137	9	by	by	IN
cord-267965-84sotgds	137	10	performing	perform	VBG
cord-267965-84sotgds	137	11	genome	genome	NN
cord-267965-84sotgds	137	12	-	-	HYPH
cord-267965-84sotgds	137	13	wide	wide	JJ
cord-267965-84sotgds	137	14	micro	micro	JJ
cord-267965-84sotgds	137	15	-	-	JJ
cord-267965-84sotgds	137	16	array	array	JJ
cord-267965-84sotgds	137	17	analysis	analysis	NN
cord-267965-84sotgds	137	18	across	across	IN
cord-267965-84sotgds	137	19	multiple	multiple	JJ
cord-267965-84sotgds	137	20	time	time	NN
cord-267965-84sotgds	137	21	points	point	NNS
cord-267965-84sotgds	137	22	post	post	NN
cord-267965-84sotgds	137	23	-	-	NN
cord-267965-84sotgds	137	24	infection	infection	NN
cord-267965-84sotgds	137	25	in	in	IN
cord-267965-84sotgds	137	26	seven	seven	CD
cord-267965-84sotgds	137	27	CC	cc	NN
cord-267965-84sotgds	137	28	-	-	HYPH
cord-267965-84sotgds	137	29	F1s	f1s	NN
cord-267965-84sotgds	137	30	carrying	carry	VBG
cord-267965-84sotgds	137	31	different	different	JJ
cord-267965-84sotgds	137	32	combinations	combination	NNS
cord-267965-84sotgds	137	33	of	of	IN
cord-267965-84sotgds	137	34	functional	functional	JJ
cord-267965-84sotgds	137	35	(	(	-LRB-
cord-267965-84sotgds	137	36	wild	wild	NN
cord-267965-84sotgds	137	37	-	-	HYPH
cord-267965-84sotgds	137	38	derived	derive	VBN
cord-267965-84sotgds	137	39	)	)	-RRB-
cord-267965-84sotgds	137	40	or	or	CC
cord-267965-84sotgds	137	41	nonfunctional	nonfunctional	JJ
cord-267965-84sotgds	137	42	(	(	-LRB-
cord-267965-84sotgds	137	43	classical	classical	JJ
cord-267965-84sotgds	137	44	inbred	inbred	JJ
cord-267965-84sotgds	137	45	strain	strain	NN
cord-267965-84sotgds	137	46	-	-	HYPH
cord-267965-84sotgds	137	47	derived	derive	VBN
cord-267965-84sotgds	137	48	)	)	-RRB-
cord-267965-84sotgds	137	49	Oas1b	oas1b	CC
cord-267965-84sotgds	137	50	haplotypes	haplotype	NNS
cord-267965-84sotgds	137	51	.	.	.
cord-267965-84sotgds	138	1	Transcriptional	transcriptional	JJ
cord-267965-84sotgds	138	2	correlation	correlation	NN
cord-267965-84sotgds	138	3	analysis	analysis	NN
cord-267965-84sotgds	138	4	of	of	IN
cord-267965-84sotgds	138	5	differentially	differentially	RB
cord-267965-84sotgds	138	6	expressed	express	VBN
cord-267965-84sotgds	138	7	immune	immune	JJ
cord-267965-84sotgds	138	8	genes	gene	NNS
cord-267965-84sotgds	138	9	across	across	IN
cord-267965-84sotgds	138	10	CC	CC	NNP
cord-267965-84sotgds	138	11	-	-	HYPH
cord-267965-84sotgds	138	12	F1s	f1s	NN
cord-267965-84sotgds	138	13	yielded	yield	VBD
cord-267965-84sotgds	138	14	three	three	CD
cord-267965-84sotgds	138	15	gene	gene	NN
cord-267965-84sotgds	138	16	clusters	cluster	NNS
cord-267965-84sotgds	138	17	,	,	,
cord-267965-84sotgds	138	18	and	and	CC
cord-267965-84sotgds	138	19	pathway	pathway	NN
cord-267965-84sotgds	138	20	analysis	analysis	NN
cord-267965-84sotgds	138	21	led	lead	VBD
cord-267965-84sotgds	138	22	to	to	IN
cord-267965-84sotgds	138	23	the	the	DT
cord-267965-84sotgds	138	24	construction	construction	NN
cord-267965-84sotgds	138	25	of	of	IN
cord-267965-84sotgds	138	26	innate	innate	JJ
cord-267965-84sotgds	138	27	immune	immune	JJ
cord-267965-84sotgds	138	28	regulatory	regulatory	JJ
cord-267965-84sotgds	138	29	networks	network	NNS
cord-267965-84sotgds	138	30	associated	associate	VBN
cord-267965-84sotgds	138	31	with	with	IN
cord-267965-84sotgds	138	32	WNV	WNV	NNP
cord-267965-84sotgds	138	33	infection	infection	NN
cord-267965-84sotgds	138	34	between	between	IN
cord-267965-84sotgds	138	35	Oas1b	oas1b	JJ
cord-267965-84sotgds	138	36	haplotype	haplotype	NN
cord-267965-84sotgds	138	37	groups	group	NNS
cord-267965-84sotgds	138	38	.	.	.
cord-267965-84sotgds	139	1	Mycobacterium	Mycobacterium	NNP
cord-267965-84sotgds	139	2	tuberculosis	tuberculosis	NN
cord-267965-84sotgds	139	3	(	(	-LRB-
cord-267965-84sotgds	139	4	Mtb	Mtb	NNP
cord-267965-84sotgds	139	5	)	)	-RRB-
cord-267965-84sotgds	139	6	infection	infection	NN
cord-267965-84sotgds	139	7	varies	vary	VBZ
cord-267965-84sotgds	139	8	broadly	broadly	RB
cord-267965-84sotgds	139	9	in	in	IN
cord-267965-84sotgds	139	10	disease	disease	NN
cord-267965-84sotgds	139	11	presentation	presentation	NN
cord-267965-84sotgds	139	12	and	and	CC
cord-267965-84sotgds	139	13	pathology	pathology	NN
cord-267965-84sotgds	139	14	in	in	IN
cord-267965-84sotgds	139	15	humans	human	NNS
cord-267965-84sotgds	139	16	.	.	.
cord-267965-84sotgds	140	1	Likewise	likewise	RB
cord-267965-84sotgds	140	2	,	,	,
cord-267965-84sotgds	140	3	the	the	DT
cord-267965-84sotgds	140	4	efficacy	efficacy	NN
cord-267965-84sotgds	140	5	of	of	IN
cord-267965-84sotgds	140	6	the	the	DT
cord-267965-84sotgds	140	7	standard	standard	JJ
cord-267965-84sotgds	140	8	TB	TB	NNP
cord-267965-84sotgds	140	9	vaccine	vaccine	NN
cord-267965-84sotgds	140	10	,	,	,
cord-267965-84sotgds	140	11	the	the	DT
cord-267965-84sotgds	140	12	live	live	RB
cord-267965-84sotgds	140	13	-	-	HYPH
cord-267965-84sotgds	140	14	attenuated	attenuate	VBN
cord-267965-84sotgds	140	15	BCG	BCG	NNP
cord-267965-84sotgds	140	16	,	,	,
cord-267965-84sotgds	140	17	is	be	VBZ
cord-267965-84sotgds	140	18	variable	variable	JJ
cord-267965-84sotgds	140	19	across	across	IN
cord-267965-84sotgds	140	20	individuals	individual	NNS
cord-267965-84sotgds	140	21	(	(	-LRB-
cord-267965-84sotgds	140	22	Mangtani	Mangtani	NNP
cord-267965-84sotgds	140	23	et	et	NNP
cord-267965-84sotgds	140	24	al	al	NNP
cord-267965-84sotgds	140	25	.	.	NNP
cord-267965-84sotgds	140	26	,	,	,
cord-267965-84sotgds	140	27	2014	2014	CD
cord-267965-84sotgds	140	28	)	)	-RRB-
cord-267965-84sotgds	140	29	.	.	.
cord-267965-84sotgds	141	1	Smith	Smith	NNP
cord-267965-84sotgds	141	2	et	et	NNP
cord-267965-84sotgds	141	3	al	al	NNP
cord-267965-84sotgds	141	4	.	.	NNP
cord-267965-84sotgds	141	5	studied	study	VBD
cord-267965-84sotgds	141	6	Mtb	Mtb	NNP
cord-267965-84sotgds	141	7	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	141	8	and	and	CC
cord-267965-84sotgds	141	9	BCG	BCG	NNP
cord-267965-84sotgds	141	10	vaccine	vaccine	NN
cord-267965-84sotgds	141	11	efficacy	efficacy	NN
cord-267965-84sotgds	141	12	in	in	IN
cord-267965-84sotgds	141	13	the	the	DT
cord-267965-84sotgds	141	14	CC	CC	NNP
cord-267965-84sotgds	141	15	founders	founder	NNS
cord-267965-84sotgds	141	16	and	and	CC
cord-267965-84sotgds	141	17	three	three	CD
cord-267965-84sotgds	141	18	RI	RI	NNP
cord-267965-84sotgds	141	19	strains	strain	NNS
cord-267965-84sotgds	141	20	that	that	WDT
cord-267965-84sotgds	141	21	were	be	VBD
cord-267965-84sotgds	141	22	selected	select	VBN
cord-267965-84sotgds	141	23	based	base	VBN
cord-267965-84sotgds	141	24	on	on	IN
cord-267965-84sotgds	141	25	a	a	DT
cord-267965-84sotgds	141	26	pilot	pilot	NN
cord-267965-84sotgds	141	27	study	study	NN
cord-267965-84sotgds	141	28	assessing	assess	VBG
cord-267965-84sotgds	141	29	Mtb	Mtb	NNP
cord-267965-84sotgds	141	30	susceptibility	susceptibility	NN
cord-267965-84sotgds	141	31	(	(	-LRB-
cord-267965-84sotgds	141	32	Smith	Smith	NNP
cord-267965-84sotgds	141	33	et	et	NNP
cord-267965-84sotgds	141	34	al	al	NNP
cord-267965-84sotgds	141	35	.	.	NNP
cord-267965-84sotgds	141	36	,	,	,
cord-267965-84sotgds	141	37	2016	2016	CD
cord-267965-84sotgds	141	38	)	)	-RRB-
cord-267965-84sotgds	141	39	.	.	.
cord-267965-84sotgds	142	1	The	the	DT
cord-267965-84sotgds	142	2	authors	author	NNS
cord-267965-84sotgds	142	3	observed	observe	VBD
cord-267965-84sotgds	142	4	a	a	DT
cord-267965-84sotgds	142	5	wide	wide	JJ
cord-267965-84sotgds	142	6	range	range	NN
cord-267965-84sotgds	142	7	of	of	IN
cord-267965-84sotgds	142	8	susceptibility	susceptibility	NN
cord-267965-84sotgds	142	9	to	to	IN
cord-267965-84sotgds	142	10	Mtb	Mtb	NNP
cord-267965-84sotgds	142	11	and	and	CC
cord-267965-84sotgds	142	12	dissociation	dissociation	NN
cord-267965-84sotgds	142	13	of	of	IN
cord-267965-84sotgds	142	14	previously	previously	RB
cord-267965-84sotgds	142	15	associated	associate	VBN
cord-267965-84sotgds	142	16	phenotypes	phenotype	NNS
cord-267965-84sotgds	142	17	such	such	JJ
cord-267965-84sotgds	142	18	as	as	IN
cord-267965-84sotgds	142	19	bacterial	bacterial	JJ
cord-267965-84sotgds	142	20	burden	burden	NN
cord-267965-84sotgds	142	21	,	,	,
cord-267965-84sotgds	142	22	immune	immune	JJ
cord-267965-84sotgds	142	23	cell	cell	NN
cord-267965-84sotgds	142	24	recruitment	recruitment	NN
cord-267965-84sotgds	142	25	,	,	,
cord-267965-84sotgds	142	26	and	and	CC
cord-267965-84sotgds	142	27	tissue	tissue	NN
cord-267965-84sotgds	142	28	damage	damage	NN
cord-267965-84sotgds	142	29	.	.	.
cord-267965-84sotgds	143	1	When	when	WRB
cord-267965-84sotgds	143	2	the	the	DT
cord-267965-84sotgds	143	3	BCG	BCG	NNP
cord-267965-84sotgds	143	4	vaccine	vaccine	NN
cord-267965-84sotgds	143	5	was	be	VBD
cord-267965-84sotgds	143	6	administered	administer	VBN
cord-267965-84sotgds	143	7	prior	prior	RB
cord-267965-84sotgds	143	8	to	to	IN
cord-267965-84sotgds	143	9	Mtb	Mtb	NNP
cord-267965-84sotgds	143	10	challenge	challenge	NN
cord-267965-84sotgds	143	11	,	,	,
cord-267965-84sotgds	143	12	vaccine	vaccine	NN
cord-267965-84sotgds	143	13	efficacy	efficacy	NN
cord-267965-84sotgds	143	14	was	be	VBD
cord-267965-84sotgds	143	15	low	low	JJ
cord-267965-84sotgds	143	16	overall	overall	RB
cord-267965-84sotgds	143	17	and	and	CC
cord-267965-84sotgds	143	18	not	not	RB
cord-267965-84sotgds	143	19	correlated	correlate	VBN
cord-267965-84sotgds	143	20	with	with	IN
cord-267965-84sotgds	143	21	susceptibility	susceptibility	NN
cord-267965-84sotgds	143	22	to	to	IN
cord-267965-84sotgds	143	23	primary	primary	JJ
cord-267965-84sotgds	143	24	infection	infection	NN
cord-267965-84sotgds	143	25	.	.	.
cord-267965-84sotgds	144	1	While	while	IN
cord-267965-84sotgds	144	2	BCG	BCG	NNP
cord-267965-84sotgds	144	3	vaccination	vaccination	NN
cord-267965-84sotgds	144	4	reduced	reduce	VBD
cord-267965-84sotgds	144	5	Mtb	Mtb	NNP
cord-267965-84sotgds	144	6	burden	burden	NN
cord-267965-84sotgds	144	7	in	in	IN
cord-267965-84sotgds	144	8	four	four	CD
cord-267965-84sotgds	144	9	strains	strain	NNS
cord-267965-84sotgds	144	10	,	,	,
cord-267965-84sotgds	144	11	there	there	EX
cord-267965-84sotgds	144	12	was	be	VBD
cord-267965-84sotgds	144	13	an	an	DT
cord-267965-84sotgds	144	14	increased	increase	VBN
cord-267965-84sotgds	144	15	bacterial	bacterial	JJ
cord-267965-84sotgds	144	16	burden	burden	NN
cord-267965-84sotgds	144	17	in	in	IN
cord-267965-84sotgds	144	18	NZO	NZO	NNP
cord-267965-84sotgds	144	19	/	/	SYM
cord-267965-84sotgds	144	20	HlLtJ	HlLtJ	NNP
cord-267965-84sotgds	144	21	mice	mouse	NNS
cord-267965-84sotgds	144	22	,	,	,
cord-267965-84sotgds	144	23	a	a	DT
cord-267965-84sotgds	144	24	model	model	NN
cord-267965-84sotgds	144	25	for	for	IN
cord-267965-84sotgds	144	26	obesity	obesity	NN
cord-267965-84sotgds	144	27	and	and	CC
cord-267965-84sotgds	144	28	type	type	NN
cord-267965-84sotgds	144	29	2	2	CD
cord-267965-84sotgds	144	30	diabetes	diabete	NNS
cord-267965-84sotgds	144	31	.	.	.
cord-267965-84sotgds	145	1	In	in	IN
cord-267965-84sotgds	145	2	addition	addition	NN
cord-267965-84sotgds	145	3	to	to	IN
cord-267965-84sotgds	145	4	highlighting	highlight	VBG
cord-267965-84sotgds	145	5	the	the	DT
cord-267965-84sotgds	145	6	importance	importance	NN
cord-267965-84sotgds	145	7	of	of	IN
cord-267965-84sotgds	145	8	host	host	NN
cord-267965-84sotgds	145	9	genetics	genetics	NN
cord-267965-84sotgds	145	10	on	on	IN
cord-267965-84sotgds	145	11	Mtb	Mtb	NNP
cord-267965-84sotgds	145	12	susceptibility	susceptibility	NN
cord-267965-84sotgds	145	13	and	and	CC
cord-267965-84sotgds	145	14	BCG	BCG	NNP
cord-267965-84sotgds	145	15	-	-	HYPH
cord-267965-84sotgds	145	16	induced	induce	VBN
cord-267965-84sotgds	145	17	vaccine	vaccine	NN
cord-267965-84sotgds	145	18	responses	response	NNS
cord-267965-84sotgds	145	19	,	,	,
cord-267965-84sotgds	145	20	the	the	DT
cord-267965-84sotgds	145	21	study	study	NN
cord-267965-84sotgds	145	22	illustrates	illustrate	VBZ
cord-267965-84sotgds	145	23	the	the	DT
cord-267965-84sotgds	145	24	potential	potential	JJ
cord-267965-84sotgds	145	25	impact	impact	NN
cord-267965-84sotgds	145	26	of	of	IN
cord-267965-84sotgds	145	27	comorbidities	comorbiditie	NNS
cord-267965-84sotgds	145	28	,	,	,
cord-267965-84sotgds	145	29	such	such	JJ
cord-267965-84sotgds	145	30	as	as	IN
cord-267965-84sotgds	145	31	type	type	NN
cord-267965-84sotgds	145	32	2	2	CD
cord-267965-84sotgds	145	33	diabetes	diabetes	NN
cord-267965-84sotgds	145	34	in	in	IN
cord-267965-84sotgds	145	35	NZO	NZO	NNP
cord-267965-84sotgds	145	36	/	/	SYM
cord-267965-84sotgds	145	37	HlLtJ	HlLtJ	NNP
cord-267965-84sotgds	145	38	mice	mouse	NNS
cord-267965-84sotgds	145	39	,	,	,
cord-267965-84sotgds	145	40	on	on	IN
cord-267965-84sotgds	145	41	vaccine	vaccine	NN
cord-267965-84sotgds	145	42	responses	response	NNS
cord-267965-84sotgds	145	43	in	in	IN
cord-267965-84sotgds	145	44	genetically	genetically	RB
cord-267965-84sotgds	145	45	diverse	diverse	JJ
cord-267965-84sotgds	145	46	populations	population	NNS
cord-267965-84sotgds	145	47	.	.	.
cord-267965-84sotgds	146	1	Maurizio	Maurizio	NNP
cord-267965-84sotgds	146	2	et	et	NNP
cord-267965-84sotgds	146	3	al	al	NNP
cord-267965-84sotgds	146	4	.	.	.
cord-267965-84sotgds	146	5	analyzed	analyze	VBD
cord-267965-84sotgds	146	6	the	the	DT
cord-267965-84sotgds	146	7	heritability	heritability	NN
cord-267965-84sotgds	146	8	of	of	IN
cord-267965-84sotgds	146	9	IAV	IAV	NNP
cord-267965-84sotgds	146	10	-	-	HYPH
cord-267965-84sotgds	146	11	induced	induce	VBN
cord-267965-84sotgds	146	12	disease	disease	NN
cord-267965-84sotgds	146	13	using	use	VBG
cord-267965-84sotgds	146	14	CC	CC	NNP
cord-267965-84sotgds	146	15	-	-	HYPH
cord-267965-84sotgds	146	16	F1s	F1s	NNP
cord-267965-84sotgds	146	17	as	as	RB
cord-267965-84sotgds	146	18	well	well	RB
cord-267965-84sotgds	146	19	as	as	IN
cord-267965-84sotgds	146	20	F1	f1	NN
cord-267965-84sotgds	146	21	crosses	cross	VBZ
cord-267965-84sotgds	146	22	between	between	IN
cord-267965-84sotgds	146	23	founder	founder	NN
cord-267965-84sotgds	146	24	strains	strain	NNS
cord-267965-84sotgds	146	25	(	(	-LRB-
cord-267965-84sotgds	146	26	Maurizio	Maurizio	NNP
cord-267965-84sotgds	146	27	et	et	NNP
cord-267965-84sotgds	146	28	al	al	NNP
cord-267965-84sotgds	146	29	.	.	NNP
cord-267965-84sotgds	146	30	,	,	,
cord-267965-84sotgds	146	31	2018	2018	CD
cord-267965-84sotgds	146	32	)	)	-RRB-
cord-267965-84sotgds	146	33	.	.	.
cord-267965-84sotgds	147	1	These	these	DT
cord-267965-84sotgds	147	2	studies	study	NNS
cord-267965-84sotgds	147	3	determined	determine	VBD
cord-267965-84sotgds	147	4	that	that	IN
cord-267965-84sotgds	147	5	IAVinduced	iavinduce	VBN
cord-267965-84sotgds	147	6	weight	weight	NN
cord-267965-84sotgds	147	7	loss	loss	NN
cord-267965-84sotgds	147	8	was	be	VBD
cord-267965-84sotgds	147	9	57	57	CD
cord-267965-84sotgds	147	10	%	%	NN
cord-267965-84sotgds	147	11	heritable	heritable	JJ
cord-267965-84sotgds	147	12	at	at	IN
cord-267965-84sotgds	147	13	day	day	NN
cord-267965-84sotgds	147	14	4	4	CD
cord-267965-84sotgds	147	15	post	post	NN
cord-267965-84sotgds	147	16	-	-	NN
cord-267965-84sotgds	147	17	infection	infection	NN
cord-267965-84sotgds	147	18	,	,	,
cord-267965-84sotgds	147	19	and	and	CC
cord-267965-84sotgds	147	20	that	that	IN
cord-267965-84sotgds	147	21	this	this	DT
cord-267965-84sotgds	147	22	heritability	heritability	NN
cord-267965-84sotgds	147	23	was	be	VBD
cord-267965-84sotgds	147	24	mostly	mostly	RB
cord-267965-84sotgds	147	25	composed	compose	VBN
cord-267965-84sotgds	147	26	of	of	IN
cord-267965-84sotgds	147	27	additive	additive	NN
cord-267965-84sotgds	147	28	effects	effect	NNS
cord-267965-84sotgds	147	29	largely	largely	RB
cord-267965-84sotgds	147	30	attributable	attributable	JJ
cord-267965-84sotgds	147	31	to	to	IN
cord-267965-84sotgds	147	32	the	the	DT
cord-267965-84sotgds	147	33	haplotype	haplotype	NN
cord-267965-84sotgds	147	34	of	of	IN
cord-267965-84sotgds	147	35	Mx1	Mx1	NNP
cord-267965-84sotgds	147	36	,	,	,
cord-267965-84sotgds	147	37	a	a	DT
cord-267965-84sotgds	147	38	polymorphic	polymorphic	JJ
cord-267965-84sotgds	147	39	largeeffect	largeeffect	JJ
cord-267965-84sotgds	147	40	anti	anti	JJ
cord-267965-84sotgds	147	41	-	-	JJ
cord-267965-84sotgds	147	42	IAV	IAV	NNP
cord-267965-84sotgds	147	43	gene	gene	NN
cord-267965-84sotgds	147	44	.	.	.
cord-267965-84sotgds	148	1	The	the	DT
cord-267965-84sotgds	148	2	genetic	genetic	JJ
cord-267965-84sotgds	148	3	dominance	dominance	NN
cord-267965-84sotgds	148	4	of	of	IN
cord-267965-84sotgds	148	5	the	the	DT
cord-267965-84sotgds	148	6	protective	protective	JJ
cord-267965-84sotgds	148	7	Mx1	mx1	JJ
cord-267965-84sotgds	148	8	haplotype	haplotype	NN
cord-267965-84sotgds	148	9	varied	varied	JJ
cord-267965-84sotgds	148	10	depending	depend	VBG
cord-267965-84sotgds	148	11	on	on	IN
cord-267965-84sotgds	148	12	subspecies	subspecies	NN
cord-267965-84sotgds	148	13	origin	origin	NN
cord-267965-84sotgds	148	14	,	,	,
cord-267965-84sotgds	148	15	with	with	IN
cord-267965-84sotgds	148	16	the	the	DT
cord-267965-84sotgds	148	17	M.	M.	NNP
cord-267965-84sotgds	148	18	musculus	musculus	NN
cord-267965-84sotgds	148	19	musculus	musculus	NN
cord-267965-84sotgds	148	20	allele	allele	NN
cord-267965-84sotgds	148	21	acting	act	VBG
cord-267965-84sotgds	148	22	dominantly	dominantly	RB
cord-267965-84sotgds	148	23	and	and	CC
cord-267965-84sotgds	148	24	the	the	DT
cord-267965-84sotgds	148	25	CAST	cast	NN
cord-267965-84sotgds	148	26	/	/	SYM
cord-267965-84sotgds	148	27	EiJ	eij	NN
cord-267965-84sotgds	148	28	allele	allele	NN
cord-267965-84sotgds	148	29	,	,	,
cord-267965-84sotgds	148	30	identified	identify	VBN
cord-267965-84sotgds	148	31	by	by	IN
cord-267965-84sotgds	148	32	Ferris	Ferris	NNP
cord-267965-84sotgds	148	33	et	et	NNP
cord-267965-84sotgds	148	34	al	al	NNP
cord-267965-84sotgds	148	35	.	.	.
cord-267965-84sotgds	149	1	(	(	-LRB-
cord-267965-84sotgds	149	2	2013	2013	CD
cord-267965-84sotgds	149	3	)	)	-RRB-
cord-267965-84sotgds	149	4	,	,	,
cord-267965-84sotgds	149	5	acting	act	VBG
cord-267965-84sotgds	149	6	additively	additively	RB
cord-267965-84sotgds	149	7	.	.	.
cord-267965-84sotgds	150	1	Consistent	consistent	JJ
cord-267965-84sotgds	150	2	with	with	IN
cord-267965-84sotgds	150	3	Ferris	Ferris	NNP
cord-267965-84sotgds	150	4	et	et	NNP
cord-267965-84sotgds	150	5	al	al	NNP
cord-267965-84sotgds	150	6	.	.	.
cord-267965-84sotgds	151	1	(	(	-LRB-
cord-267965-84sotgds	151	2	discussed	discuss	VBN
cord-267965-84sotgds	151	3	below	below	RB
cord-267965-84sotgds	151	4	)	)	-RRB-
cord-267965-84sotgds	151	5	,	,	,
cord-267965-84sotgds	151	6	these	these	DT
cord-267965-84sotgds	151	7	authors	author	NNS
cord-267965-84sotgds	151	8	determined	determine	VBD
cord-267965-84sotgds	151	9	that	that	IN
cord-267965-84sotgds	151	10	when	when	WRB
cord-267965-84sotgds	151	11	controlling	control	VBG
cord-267965-84sotgds	151	12	for	for	IN
cord-267965-84sotgds	151	13	Mx1	mx1	JJ
cord-267965-84sotgds	151	14	,	,	,
cord-267965-84sotgds	151	15	non	non	JJ
cord-267965-84sotgds	151	16	-	-	JJ
cord-267965-84sotgds	151	17	Mx1	mx1	JJ
cord-267965-84sotgds	151	18	heritable	heritable	JJ
cord-267965-84sotgds	151	19	effects	effect	NNS
cord-267965-84sotgds	151	20	still	still	RB
cord-267965-84sotgds	151	21	accounted	account	VBD
cord-267965-84sotgds	151	22	for	for	IN
cord-267965-84sotgds	151	23	34	34	CD
cord-267965-84sotgds	151	24	%	%	NN
cord-267965-84sotgds	151	25	of	of	IN
cord-267965-84sotgds	151	26	the	the	DT
cord-267965-84sotgds	151	27	phenotypic	phenotypic	JJ
cord-267965-84sotgds	151	28	variation	variation	NN
cord-267965-84sotgds	151	29	,	,	,
cord-267965-84sotgds	151	30	and	and	CC
cord-267965-84sotgds	151	31	this	this	DT
cord-267965-84sotgds	151	32	effect	effect	NN
cord-267965-84sotgds	151	33	was	be	VBD
cord-267965-84sotgds	151	34	consistent	consistent	JJ
cord-267965-84sotgds	151	35	across	across	IN
cord-267965-84sotgds	151	36	founder	founder	NN
cord-267965-84sotgds	151	37	diallel	diallel	NNS
cord-267965-84sotgds	151	38	,	,	,
cord-267965-84sotgds	151	39	pre	pre	JJ
cord-267965-84sotgds	151	40	-	-	NN
cord-267965-84sotgds	151	41	CC	CC	NNP
cord-267965-84sotgds	151	42	,	,	,
cord-267965-84sotgds	151	43	and	and	CC
cord-267965-84sotgds	151	44	CC	CC	NNP
cord-267965-84sotgds	151	45	-	-	HYPH
cord-267965-84sotgds	151	46	F1	F1	NNP
cord-267965-84sotgds	151	47	populations	population	NNS
cord-267965-84sotgds	151	48	.	.	.
cord-267965-84sotgds	152	1	Human	human	JJ
cord-267965-84sotgds	152	2	studies	study	NNS
cord-267965-84sotgds	152	3	have	have	VBP
cord-267965-84sotgds	152	4	identified	identify	VBN
cord-267965-84sotgds	152	5	blood	blood	NN
cord-267965-84sotgds	152	6	transcriptomic	transcriptomic	JJ
cord-267965-84sotgds	152	7	and	and	CC
cord-267965-84sotgds	152	8	proteomic	proteomic	JJ
cord-267965-84sotgds	152	9	signatures	signature	NNS
cord-267965-84sotgds	152	10	associated	associate	VBN
cord-267965-84sotgds	152	11	with	with	IN
cord-267965-84sotgds	152	12	IAV	IAV	NNP
cord-267965-84sotgds	152	13	infection	infection	NN
cord-267965-84sotgds	152	14	that	that	WDT
cord-267965-84sotgds	152	15	could	could	MD
cord-267965-84sotgds	152	16	be	be	VB
cord-267965-84sotgds	152	17	used	use	VBN
cord-267965-84sotgds	152	18	to	to	TO
cord-267965-84sotgds	152	19	predict	predict	VB
cord-267965-84sotgds	152	20	patient	patient	JJ
cord-267965-84sotgds	152	21	outcome	outcome	NN
cord-267965-84sotgds	152	22	.	.	.
cord-267965-84sotgds	153	1	Elbahesh	Elbahesh	NNP
cord-267965-84sotgds	153	2	and	and	CC
cord-267965-84sotgds	153	3	Schughart	Schughart	NNP
cord-267965-84sotgds	153	4	observed	observe	VBD
cord-267965-84sotgds	153	5	that	that	IN
cord-267965-84sotgds	153	6	gene	gene	NN
cord-267965-84sotgds	153	7	signatures	signature	NNS
cord-267965-84sotgds	153	8	from	from	IN
cord-267965-84sotgds	153	9	IAV	IAV	NNP
cord-267965-84sotgds	153	10	-	-	HYPH
cord-267965-84sotgds	153	11	infected	infect	VBN
cord-267965-84sotgds	153	12	humans	human	NNS
cord-267965-84sotgds	153	13	were	be	VBD
cord-267965-84sotgds	153	14	reproduced	reproduce	VBN
cord-267965-84sotgds	153	15	in	in	IN
cord-267965-84sotgds	153	16	the	the	DT
cord-267965-84sotgds	153	17	peripheral	peripheral	JJ
cord-267965-84sotgds	153	18	blood	blood	NN
cord-267965-84sotgds	153	19	of	of	IN
cord-267965-84sotgds	153	20	CC	CC	NNP
cord-267965-84sotgds	153	21	founders	founder	NNS
cord-267965-84sotgds	153	22	(	(	-LRB-
cord-267965-84sotgds	153	23	Elbahesh	Elbahesh	NNP
cord-267965-84sotgds	153	24	and	and	CC
cord-267965-84sotgds	153	25	Schughart	Schughart	NNP
cord-267965-84sotgds	153	26	,	,	,
cord-267965-84sotgds	153	27	2016	2016	CD
cord-267965-84sotgds	153	28	)	)	-RRB-
cord-267965-84sotgds	153	29	.	.	.
cord-267965-84sotgds	154	1	In	in	IN
cord-267965-84sotgds	154	2	a	a	DT
cord-267965-84sotgds	154	3	follow	follow	NN
cord-267965-84sotgds	154	4	-	-	HYPH
cord-267965-84sotgds	154	5	up	up	NN
cord-267965-84sotgds	154	6	study	study	NN
cord-267965-84sotgds	154	7	,	,	,
cord-267965-84sotgds	154	8	Kollmus	Kollmus	NNP
cord-267965-84sotgds	154	9	et	et	NNP
cord-267965-84sotgds	154	10	al	al	NNP
cord-267965-84sotgds	154	11	.	.	NNP
cord-267965-84sotgds	154	12	characterized	characterize	VBD
cord-267965-84sotgds	154	13	the	the	DT
cord-267965-84sotgds	154	14	transcriptional	transcriptional	JJ
cord-267965-84sotgds	154	15	response	response	NN
cord-267965-84sotgds	154	16	to	to	IN
cord-267965-84sotgds	154	17	IAV	IAV	NNP
cord-267965-84sotgds	154	18	in	in	IN
cord-267965-84sotgds	154	19	the	the	DT
cord-267965-84sotgds	154	20	peripheral	peripheral	JJ
cord-267965-84sotgds	154	21	blood	blood	NN
cord-267965-84sotgds	154	22	of	of	IN
cord-267965-84sotgds	154	23	eleven	eleven	CD
cord-267965-84sotgds	154	24	CC	cc	NN
cord-267965-84sotgds	154	25	strains	strain	NNS
cord-267965-84sotgds	154	26	(	(	-LRB-
cord-267965-84sotgds	154	27	Kollmus	Kollmus	NNP
cord-267965-84sotgds	154	28	et	et	NNP
cord-267965-84sotgds	154	29	al	al	NNP
cord-267965-84sotgds	154	30	.	.	NNP
cord-267965-84sotgds	154	31	,	,	,
cord-267965-84sotgds	154	32	2018	2018	CD
cord-267965-84sotgds	154	33	)	)	-RRB-
cord-267965-84sotgds	154	34	.	.	.
cord-267965-84sotgds	155	1	Though	though	IN
cord-267965-84sotgds	155	2	both	both	DT
cord-267965-84sotgds	155	3	human	human	JJ
cord-267965-84sotgds	155	4	and	and	CC
cord-267965-84sotgds	155	5	mouse	mouse	NN
cord-267965-84sotgds	155	6	datasets	dataset	NNS
cord-267965-84sotgds	155	7	were	be	VBD
cord-267965-84sotgds	155	8	globally	globally	RB
cord-267965-84sotgds	155	9	heterogeneous	heterogeneous	JJ
cord-267965-84sotgds	155	10	,	,	,
cord-267965-84sotgds	155	11	the	the	DT
cord-267965-84sotgds	155	12	CC	CC	NNP
cord-267965-84sotgds	155	13	dataset	dataset	NN
cord-267965-84sotgds	155	14	showed	show	VBD
cord-267965-84sotgds	155	15	that	that	IN
cord-267965-84sotgds	155	16	genetic	genetic	JJ
cord-267965-84sotgds	155	17	background	background	NN
cord-267965-84sotgds	155	18	strongly	strongly	RB
cord-267965-84sotgds	155	19	influenced	influence	VBD
cord-267965-84sotgds	155	20	gene	gene	NN
cord-267965-84sotgds	155	21	expression	expression	NN
cord-267965-84sotgds	155	22	,	,	,
cord-267965-84sotgds	155	23	highlighting	highlight	VBG
cord-267965-84sotgds	155	24	the	the	DT
cord-267965-84sotgds	155	25	importance	importance	NN
cord-267965-84sotgds	155	26	of	of	IN
cord-267965-84sotgds	155	27	genetics	genetic	NNS
cord-267965-84sotgds	155	28	in	in	IN
cord-267965-84sotgds	155	29	driving	drive	VBG
cord-267965-84sotgds	155	30	the	the	DT
cord-267965-84sotgds	155	31	immune	immune	JJ
cord-267965-84sotgds	155	32	response	response	NN
cord-267965-84sotgds	155	33	.	.	.
cord-267965-84sotgds	156	1	For	for	IN
cord-267965-84sotgds	156	2	the	the	DT
cord-267965-84sotgds	156	3	most	most	RBS
cord-267965-84sotgds	156	4	differentially	differentially	RB
cord-267965-84sotgds	156	5	expressed	express	VBN
cord-267965-84sotgds	156	6	genes	gene	NNS
cord-267965-84sotgds	156	7	,	,	,
cord-267965-84sotgds	156	8	the	the	DT
cord-267965-84sotgds	156	9	transcriptional	transcriptional	JJ
cord-267965-84sotgds	156	10	responses	response	NNS
cord-267965-84sotgds	156	11	in	in	IN
cord-267965-84sotgds	156	12	mice	mouse	NNS
cord-267965-84sotgds	156	13	and	and	CC
cord-267965-84sotgds	156	14	humans	human	NNS
cord-267965-84sotgds	156	15	were	be	VBD
cord-267965-84sotgds	156	16	largely	largely	RB
cord-267965-84sotgds	156	17	similar	similar	JJ
cord-267965-84sotgds	156	18	,	,	,
cord-267965-84sotgds	156	19	demonstrating	demonstrate	VBG
cord-267965-84sotgds	156	20	the	the	DT
cord-267965-84sotgds	156	21	utility	utility	NN
cord-267965-84sotgds	156	22	of	of	IN
cord-267965-84sotgds	156	23	the	the	DT
cord-267965-84sotgds	156	24	CC	CC	NNP
cord-267965-84sotgds	156	25	in	in	IN
cord-267965-84sotgds	156	26	recapitulating	recapitulate	VBG
cord-267965-84sotgds	156	27	IAV	iav	NN
cord-267965-84sotgds	156	28	-	-	HYPH
cord-267965-84sotgds	156	29	induced	induce	VBN
cord-267965-84sotgds	156	30	host	host	NN
cord-267965-84sotgds	156	31	response	response	NN
cord-267965-84sotgds	156	32	in	in	IN
cord-267965-84sotgds	156	33	humans	human	NNS
cord-267965-84sotgds	156	34	.	.	.
cord-267965-84sotgds	157	1	Xiong	Xiong	NNP
cord-267965-84sotgds	157	2	et	et	NNP
cord-267965-84sotgds	157	3	al	al	NNP
cord-267965-84sotgds	157	4	.	.	.
cord-267965-84sotgds	158	1	characterized	characterize	VBD
cord-267965-84sotgds	158	2	transcriptomic	transcriptomic	JJ
cord-267965-84sotgds	158	3	variation	variation	NN
cord-267965-84sotgds	158	4	in	in	IN
cord-267965-84sotgds	158	5	response	response	NN
cord-267965-84sotgds	158	6	to	to	IN
cord-267965-84sotgds	158	7	severe	severe	JJ
cord-267965-84sotgds	158	8	acute	acute	JJ
cord-267965-84sotgds	158	9	respiratory	respiratory	JJ
cord-267965-84sotgds	158	10	syndrome	syndrome	NN
cord-267965-84sotgds	158	11	coronavirus	coronavirus	NN
cord-267965-84sotgds	158	12	(	(	-LRB-
cord-267965-84sotgds	158	13	SARS	SARS	NNP
cord-267965-84sotgds	158	14	-	-	HYPH
cord-267965-84sotgds	158	15	CoV	CoV	NNP
cord-267965-84sotgds	158	16	)	)	-RRB-
cord-267965-84sotgds	158	17	and	and	CC
cord-267965-84sotgds	158	18	IAV	IAV	NNP
cord-267965-84sotgds	158	19	across	across	IN
cord-267965-84sotgds	158	20	the	the	DT
cord-267965-84sotgds	158	21	eight	eight	CD
cord-267965-84sotgds	158	22	CC	CC	NNP
cord-267965-84sotgds	158	23	founder	founder	NN
cord-267965-84sotgds	158	24	strains	strain	NNS
cord-267965-84sotgds	158	25	(	(	-LRB-
cord-267965-84sotgds	158	26	Xiong	Xiong	NNP
cord-267965-84sotgds	158	27	et	et	NNP
cord-267965-84sotgds	158	28	al	al	NNP
cord-267965-84sotgds	158	29	.	.	NNP
cord-267965-84sotgds	158	30	,	,	,
cord-267965-84sotgds	158	31	2014	2014	CD
cord-267965-84sotgds	158	32	)	)	-RRB-
cord-267965-84sotgds	158	33	.	.	.
cord-267965-84sotgds	159	1	Differential	differential	JJ
cord-267965-84sotgds	159	2	gene	gene	NN
cord-267965-84sotgds	159	3	expression	expression	NN
cord-267965-84sotgds	159	4	analysis	analysis	NN
cord-267965-84sotgds	159	5	at	at	IN
cord-267965-84sotgds	159	6	days	day	NNS
cord-267965-84sotgds	159	7	2	2	CD
cord-267965-84sotgds	159	8	and	and	CC
cord-267965-84sotgds	159	9	4	4	CD
cord-267965-84sotgds	159	10	post	post	NN
cord-267965-84sotgds	160	1	SARS	SARS	NNP
cord-267965-84sotgds	160	2	-	-	HYPH
cord-267965-84sotgds	160	3	CoV	CoV	NNP
cord-267965-84sotgds	160	4	or	or	CC
cord-267965-84sotgds	160	5	IAV	IAV	NNP
cord-267965-84sotgds	160	6	infection	infection	NN
cord-267965-84sotgds	160	7	showed	show	VBD
cord-267965-84sotgds	160	8	significant	significant	JJ
cord-267965-84sotgds	160	9	differences	difference	NNS
cord-267965-84sotgds	160	10	driven	drive	VBN
cord-267965-84sotgds	160	11	by	by	IN
cord-267965-84sotgds	160	12	mouse	mouse	NN
cord-267965-84sotgds	160	13	strain	strain	NN
cord-267965-84sotgds	160	14	,	,	,
cord-267965-84sotgds	160	15	infection	infection	NN
cord-267965-84sotgds	160	16	status	status	NN
cord-267965-84sotgds	160	17	,	,	,
cord-267965-84sotgds	160	18	and	and	CC
cord-267965-84sotgds	160	19	time	time	NN
cord-267965-84sotgds	160	20	point	point	NN
cord-267965-84sotgds	160	21	.	.	.
cord-267965-84sotgds	161	1	Genes	gene	NNS
cord-267965-84sotgds	161	2	with	with	IN
cord-267965-84sotgds	161	3	strain	strain	NN
cord-267965-84sotgds	161	4	-	-	HYPH
cord-267965-84sotgds	161	5	specific	specific	JJ
cord-267965-84sotgds	161	6	differential	differential	JJ
cord-267965-84sotgds	161	7	expression	expression	NN
cord-267965-84sotgds	161	8	patterns	pattern	NNS
cord-267965-84sotgds	161	9	were	be	VBD
cord-267965-84sotgds	161	10	largely	largely	RB
cord-267965-84sotgds	161	11	enriched	enrich	VBN
cord-267965-84sotgds	161	12	for	for	IN
cord-267965-84sotgds	161	13	immune	immune	JJ
cord-267965-84sotgds	161	14	pathways	pathway	NNS
cord-267965-84sotgds	161	15	,	,	,
cord-267965-84sotgds	161	16	while	while	IN
cord-267965-84sotgds	161	17	more	more	RBR
cord-267965-84sotgds	161	18	generic	generic	JJ
cord-267965-84sotgds	161	19	differential	differential	JJ
cord-267965-84sotgds	161	20	expression	expression	NN
cord-267965-84sotgds	161	21	patterns	pattern	NNS
cord-267965-84sotgds	161	22	were	be	VBD
cord-267965-84sotgds	161	23	enriched	enrich	VBN
cord-267965-84sotgds	161	24	for	for	IN
cord-267965-84sotgds	161	25	basic	basic	JJ
cord-267965-84sotgds	161	26	biological	biological	JJ
cord-267965-84sotgds	161	27	functions	function	NNS
cord-267965-84sotgds	161	28	.	.	.
cord-267965-84sotgds	162	1	The	the	DT
cord-267965-84sotgds	162	2	study	study	NN
cord-267965-84sotgds	162	3	also	also	RB
cord-267965-84sotgds	162	4	noted	note	VBD
cord-267965-84sotgds	162	5	the	the	DT
cord-267965-84sotgds	162	6	presence	presence	NN
cord-267965-84sotgds	162	7	of	of	IN
cord-267965-84sotgds	162	8	strain	strain	NN
cord-267965-84sotgds	162	9	-	-	HYPH
cord-267965-84sotgds	162	10	specific	specific	JJ
cord-267965-84sotgds	162	11	isoforms	isoform	NNS
cord-267965-84sotgds	162	12	and	and	CC
cord-267965-84sotgds	162	13	novel	novel	NN
cord-267965-84sotgds	162	14	transcripts	transcript	NNS
cord-267965-84sotgds	162	15	not	not	RB
cord-267965-84sotgds	162	16	present	present	JJ
cord-267965-84sotgds	162	17	in	in	IN
cord-267965-84sotgds	162	18	the	the	DT
cord-267965-84sotgds	162	19	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	162	20	reference	reference	NN
cord-267965-84sotgds	162	21	annotation	annotation	NN
cord-267965-84sotgds	162	22	.	.	.
cord-267965-84sotgds	163	1	Pseudomonas	Pseudomonas	NNP
cord-267965-84sotgds	163	2	aeruginosa	aeruginosa	NN
cord-267965-84sotgds	163	3	is	be	VBZ
cord-267965-84sotgds	163	4	an	an	DT
cord-267965-84sotgds	163	5	opportunistic	opportunistic	JJ
cord-267965-84sotgds	163	6	bacterial	bacterial	JJ
cord-267965-84sotgds	163	7	pathogen	pathogen	NN
cord-267965-84sotgds	163	8	with	with	IN
cord-267965-84sotgds	163	9	variable	variable	JJ
cord-267965-84sotgds	163	10	clinical	clinical	JJ
cord-267965-84sotgds	163	11	outcomes	outcome	NNS
cord-267965-84sotgds	163	12	across	across	IN
cord-267965-84sotgds	163	13	susceptible	susceptible	JJ
cord-267965-84sotgds	163	14	individuals	individual	NNS
cord-267965-84sotgds	163	15	.	.	.
cord-267965-84sotgds	164	1	Human	human	JJ
cord-267965-84sotgds	164	2	studies	study	NNS
cord-267965-84sotgds	164	3	,	,	,
cord-267965-84sotgds	164	4	including	include	VBG
cord-267965-84sotgds	164	5	twin	twin	JJ
cord-267965-84sotgds	164	6	studies	study	NNS
cord-267965-84sotgds	164	7	as	as	RB
cord-267965-84sotgds	164	8	well	well	RB
cord-267965-84sotgds	164	9	as	as	IN
cord-267965-84sotgds	164	10	association	association	NN
cord-267965-84sotgds	164	11	studies	study	NNS
cord-267965-84sotgds	164	12	,	,	,
cord-267965-84sotgds	164	13	have	have	VBP
cord-267965-84sotgds	164	14	identified	identify	VBN
cord-267965-84sotgds	164	15	multiple	multiple	JJ
cord-267965-84sotgds	164	16	genes	gene	NNS
cord-267965-84sotgds	164	17	associated	associate	VBN
cord-267965-84sotgds	164	18	with	with	IN
cord-267965-84sotgds	164	19	susceptibility	susceptibility	NN
cord-267965-84sotgds	164	20	to	to	IN
cord-267965-84sotgds	164	21	P.	P.	NNP
cord-267965-84sotgds	164	22	aeruginosa	aeruginosa	NN
cord-267965-84sotgds	164	23	.	.	.
cord-267965-84sotgds	165	1	Lorè	Lorè	NNP
cord-267965-84sotgds	165	2	et	et	NNP
cord-267965-84sotgds	165	3	al	al	NNP
cord-267965-84sotgds	165	4	.	.	NNP
cord-267965-84sotgds	165	5	studied	study	VBD
cord-267965-84sotgds	165	6	P.	P.	NNP
cord-267965-84sotgds	165	7	aeruginosa	aeruginosa	NN
cord-267965-84sotgds	165	8	infection	infection	NN
cord-267965-84sotgds	165	9	in	in	IN
cord-267965-84sotgds	165	10	17	17	CD
cord-267965-84sotgds	165	11	pre	pre	JJ
cord-267965-84sotgds	165	12	-	-	JJ
cord-267965-84sotgds	165	13	CC	cc	JJ
cord-267965-84sotgds	165	14	lines	line	NNS
cord-267965-84sotgds	165	15	,	,	,
cord-267965-84sotgds	165	16	focusing	focus	VBG
cord-267965-84sotgds	165	17	on	on	IN
cord-267965-84sotgds	165	18	survival	survival	NN
cord-267965-84sotgds	165	19	time	time	NN
cord-267965-84sotgds	165	20	and	and	CC
cord-267965-84sotgds	165	21	early	early	JJ
cord-267965-84sotgds	165	22	body	body	NN
cord-267965-84sotgds	165	23	weight	weight	NN
cord-267965-84sotgds	165	24	change	change	NN
cord-267965-84sotgds	165	25	,	,	,
cord-267965-84sotgds	165	26	and	and	CC
cord-267965-84sotgds	165	27	observed	observe	VBD
cord-267965-84sotgds	165	28	a	a	DT
cord-267965-84sotgds	165	29	large	large	JJ
cord-267965-84sotgds	165	30	amount	amount	NN
cord-267965-84sotgds	165	31	of	of	IN
cord-267965-84sotgds	165	32	variation	variation	NN
cord-267965-84sotgds	165	33	in	in	IN
cord-267965-84sotgds	165	34	these	these	DT
cord-267965-84sotgds	165	35	phenotypes	phenotype	NNS
cord-267965-84sotgds	165	36	(	(	-LRB-
cord-267965-84sotgds	165	37	Lorè	Lorè	NNP
cord-267965-84sotgds	165	38	et	et	FW
cord-267965-84sotgds	165	39	al	al	NNP
cord-267965-84sotgds	165	40	.	.	NNP
cord-267965-84sotgds	165	41	,	,	,
cord-267965-84sotgds	165	42	2015	2015	CD
cord-267965-84sotgds	165	43	)	)	-RRB-
cord-267965-84sotgds	165	44	.	.	.
cord-267965-84sotgds	166	1	Genetic	genetic	JJ
cord-267965-84sotgds	166	2	Mapping	mapping	NN
cord-267965-84sotgds	166	3	of	of	IN
cord-267965-84sotgds	166	4	Disease	Disease	NNP
cord-267965-84sotgds	166	5	Response	Response	NNP
cord-267965-84sotgds	166	6	in	in	IN
cord-267965-84sotgds	166	7	the	the	DT
cord-267965-84sotgds	166	8	CC	cc	NN
cord-267965-84sotgds	167	1	As	as	IN
cord-267965-84sotgds	167	2	described	describe	VBN
cord-267965-84sotgds	167	3	above	above	RB
cord-267965-84sotgds	167	4	,	,	,
cord-267965-84sotgds	167	5	the	the	DT
cord-267965-84sotgds	167	6	CC	CC	NNP
cord-267965-84sotgds	167	7	was	be	VBD
cord-267965-84sotgds	167	8	initially	initially	RB
cord-267965-84sotgds	167	9	envisioned	envision	VBN
cord-267965-84sotgds	167	10	as	as	IN
cord-267965-84sotgds	167	11	a	a	DT
cord-267965-84sotgds	167	12	genetic	genetic	JJ
cord-267965-84sotgds	167	13	mapping	mapping	NN
cord-267965-84sotgds	167	14	population	population	NN
cord-267965-84sotgds	167	15	with	with	IN
cord-267965-84sotgds	167	16	approximately	approximately	RB
cord-267965-84sotgds	167	17	1,000	1,000	CD
cord-267965-84sotgds	167	18	strains	strain	NNS
cord-267965-84sotgds	167	19	(	(	-LRB-
cord-267965-84sotgds	167	20	Threadgill	Threadgill	NNP
cord-267965-84sotgds	167	21	et	et	NNP
cord-267965-84sotgds	167	22	al	al	NNP
cord-267965-84sotgds	167	23	.	.	NNP
cord-267965-84sotgds	167	24	,	,	,
cord-267965-84sotgds	167	25	2002	2002	CD
cord-267965-84sotgds	167	26	)	)	-RRB-
cord-267965-84sotgds	167	27	.	.	.
cord-267965-84sotgds	168	1	While	while	IN
cord-267965-84sotgds	168	2	the	the	DT
cord-267965-84sotgds	168	3	number	number	NN
cord-267965-84sotgds	168	4	of	of	IN
cord-267965-84sotgds	168	5	available	available	JJ
cord-267965-84sotgds	168	6	CC	cc	NN
cord-267965-84sotgds	168	7	RI	RI	NNP
cord-267965-84sotgds	168	8	strains	strain	NNS
cord-267965-84sotgds	168	9	is	be	VBZ
cord-267965-84sotgds	168	10	closer	close	JJR
cord-267965-84sotgds	168	11	to	to	IN
cord-267965-84sotgds	168	12	100	100	CD
cord-267965-84sotgds	168	13	,	,	,
cord-267965-84sotgds	168	14	this	this	DT
cord-267965-84sotgds	168	15	population	population	NN
cord-267965-84sotgds	168	16	has	have	VBZ
cord-267965-84sotgds	168	17	proven	prove	VBN
cord-267965-84sotgds	168	18	to	to	TO
cord-267965-84sotgds	168	19	be	be	VB
cord-267965-84sotgds	168	20	sufficient	sufficient	JJ
cord-267965-84sotgds	168	21	for	for	IN
cord-267965-84sotgds	168	22	successful	successful	JJ
cord-267965-84sotgds	168	23	QTL	QTL	NNP
cord-267965-84sotgds	168	24	mapping	mapping	NN
cord-267965-84sotgds	168	25	.	.	.
cord-267965-84sotgds	169	1	Mapping	mapping	NN
cord-267965-84sotgds	169	2	studies	study	NNS
cord-267965-84sotgds	169	3	have	have	VBP
cord-267965-84sotgds	169	4	identified	identify	VBN
cord-267965-84sotgds	169	5	QTLs	qtl	NNS
cord-267965-84sotgds	169	6	spanning	span	VBG
cord-267965-84sotgds	169	7	the	the	DT
cord-267965-84sotgds	169	8	genome	genome	NN
cord-267965-84sotgds	169	9	that	that	WDT
cord-267965-84sotgds	169	10	are	be	VBP
cord-267965-84sotgds	169	11	driven	drive	VBN
cord-267965-84sotgds	169	12	by	by	IN
cord-267965-84sotgds	169	13	variants	variant	NNS
cord-267965-84sotgds	169	14	from	from	IN
cord-267965-84sotgds	169	15	all	all	DT
cord-267965-84sotgds	169	16	eight	eight	CD
cord-267965-84sotgds	169	17	CC	CC	NNP
cord-267965-84sotgds	169	18	founders	founder	NNS
cord-267965-84sotgds	169	19	and	and	CC
cord-267965-84sotgds	169	20	show	show	VBP
cord-267965-84sotgds	169	21	very	very	RB
cord-267965-84sotgds	169	22	little	little	JJ
cord-267965-84sotgds	169	23	overlap	overlap	VBP
cord-267965-84sotgds	169	24	across	across	IN
cord-267965-84sotgds	169	25	pathogens	pathogen	NNS
cord-267965-84sotgds	169	26	(	(	-LRB-
cord-267965-84sotgds	169	27	Figure	figure	NN
cord-267965-84sotgds	169	28	2	2	CD
cord-267965-84sotgds	169	29	;	;	:
cord-267965-84sotgds	169	30	Table	table	NN
cord-267965-84sotgds	169	31	1	1	CD
cord-267965-84sotgds	169	32	;	;	:
cord-267965-84sotgds	169	33	discussed	discuss	VBN
cord-267965-84sotgds	169	34	below	below	RB
cord-267965-84sotgds	169	35	)	)	-RRB-
cord-267965-84sotgds	169	36	.	.	.
cord-267965-84sotgds	170	1	Overall	overall	RB
cord-267965-84sotgds	170	2	,	,	,
cord-267965-84sotgds	170	3	infectious	infectious	JJ
cord-267965-84sotgds	170	4	disease	disease	NN
cord-267965-84sotgds	170	5	phenotypes	phenotype	NNS
cord-267965-84sotgds	170	6	mapped	map	VBN
cord-267965-84sotgds	170	7	in	in	IN
cord-267965-84sotgds	170	8	the	the	DT
cord-267965-84sotgds	170	9	CC	CC	NNP
cord-267965-84sotgds	170	10	show	show	VBP
cord-267965-84sotgds	170	11	a	a	DT
cord-267965-84sotgds	170	12	broad	broad	JJ
cord-267965-84sotgds	170	13	range	range	NN
cord-267965-84sotgds	170	14	in	in	IN
cord-267965-84sotgds	170	15	overall	overall	JJ
cord-267965-84sotgds	170	16	heritability	heritability	NN
cord-267965-84sotgds	170	17	(	(	-LRB-
cord-267965-84sotgds	170	18	the	the	DT
cord-267965-84sotgds	170	19	proportion	proportion	NN
cord-267965-84sotgds	170	20	of	of	IN
cord-267965-84sotgds	170	21	population	population	NN
cord-267965-84sotgds	170	22	-	-	HYPH
cord-267965-84sotgds	170	23	wide	wide	JJ
cord-267965-84sotgds	170	24	variation	variation	NN
cord-267965-84sotgds	170	25	explained	explain	VBN
cord-267965-84sotgds	170	26	by	by	IN
cord-267965-84sotgds	170	27	differences	difference	NNS
cord-267965-84sotgds	170	28	between	between	IN
cord-267965-84sotgds	170	29	strains	strain	NNS
cord-267965-84sotgds	170	30	)	)	-RRB-
cord-267965-84sotgds	170	31	as	as	RB
cord-267965-84sotgds	170	32	well	well	RB
cord-267965-84sotgds	170	33	as	as	IN
cord-267965-84sotgds	170	34	effect	effect	NN
cord-267965-84sotgds	170	35	sizes	size	NNS
cord-267965-84sotgds	170	36	(	(	-LRB-
cord-267965-84sotgds	170	37	the	the	DT
cord-267965-84sotgds	170	38	proportion	proportion	NN
cord-267965-84sotgds	170	39	of	of	IN
cord-267965-84sotgds	170	40	population	population	NN
cord-267965-84sotgds	170	41	-	-	HYPH
cord-267965-84sotgds	170	42	wide	wide	JJ
cord-267965-84sotgds	170	43	variation	variation	NN
cord-267965-84sotgds	170	44	explained	explain	VBN
cord-267965-84sotgds	170	45	by	by	IN
cord-267965-84sotgds	170	46	specific	specific	JJ
cord-267965-84sotgds	170	47	loci	locus	NNS
cord-267965-84sotgds	170	48	)	)	-RRB-
cord-267965-84sotgds	170	49	.	.	.
cord-267965-84sotgds	171	1	Across	across	IN
cord-267965-84sotgds	171	2	the	the	DT
cord-267965-84sotgds	171	3	studies	study	NNS
cord-267965-84sotgds	171	4	described	describe	VBN
cord-267965-84sotgds	171	5	in	in	IN
cord-267965-84sotgds	171	6	Table	Table	NNP
cord-267965-84sotgds	171	7	1	1	CD
cord-267965-84sotgds	171	8	,	,	,
cord-267965-84sotgds	171	9	reported	report	VBD
cord-267965-84sotgds	171	10	estimates	estimate	NNS
cord-267965-84sotgds	171	11	for	for	IN
cord-267965-84sotgds	171	12	heritability	heritability	NN
cord-267965-84sotgds	171	13	range	range	NN
cord-267965-84sotgds	171	14	from	from	IN
cord-267965-84sotgds	171	15	12	12	CD
cord-267965-84sotgds	171	16	%	%	NN
cord-267965-84sotgds	171	17	to	to	IN
cord-267965-84sotgds	171	18	over	over	IN
cord-267965-84sotgds	171	19	80	80	CD
cord-267965-84sotgds	171	20	%	%	NN
cord-267965-84sotgds	171	21	,	,	,
cord-267965-84sotgds	171	22	while	while	IN
cord-267965-84sotgds	171	23	reported	report	VBN
cord-267965-84sotgds	171	24	estimates	estimate	NNS
cord-267965-84sotgds	171	25	for	for	IN
cord-267965-84sotgds	171	26	effect	effect	NN
cord-267965-84sotgds	171	27	size	size	NN
cord-267965-84sotgds	171	28	range	range	NN
cord-267965-84sotgds	171	29	from	from	IN
cord-267965-84sotgds	171	30	5	5	CD
cord-267965-84sotgds	171	31	%	%	NN
cord-267965-84sotgds	171	32	(	(	-LRB-
cord-267965-84sotgds	171	33	for	for	IN
cord-267965-84sotgds	171	34	a	a	DT
cord-267965-84sotgds	171	35	QTL	QTL	NNP
cord-267965-84sotgds	171	36	of	of	IN
cord-267965-84sotgds	171	37	small	small	JJ
cord-267965-84sotgds	171	38	effect	effect	NN
cord-267965-84sotgds	171	39	influencing	influence	VBG
cord-267965-84sotgds	171	40	SARS	SARS	NNP
cord-267965-84sotgds	171	41	-	-	HYPH
cord-267965-84sotgds	171	42	CoV	CoV	NNP
cord-267965-84sotgds	171	43	viral	viral	NNP
cord-267965-84sotgds	171	44	titer	titer	NN
cord-267965-84sotgds	171	45	)	)	-RRB-
cord-267965-84sotgds	171	46	to	to	IN
cord-267965-84sotgds	171	47	over	over	IN
cord-267965-84sotgds	171	48	40	40	CD
cord-267965-84sotgds	171	49	%	%	NN
cord-267965-84sotgds	171	50	(	(	-LRB-
cord-267965-84sotgds	171	51	for	for	IN
cord-267965-84sotgds	171	52	a	a	DT
cord-267965-84sotgds	171	53	large	large	JJ
cord-267965-84sotgds	171	54	effect	effect	NN
cord-267965-84sotgds	171	55	QTL	qtl	NN
cord-267965-84sotgds	171	56	containing	contain	VBG
cord-267965-84sotgds	171	57	the	the	DT
cord-267965-84sotgds	171	58	gene	gene	NN
cord-267965-84sotgds	171	59	Mx1	mx1	JJ
cord-267965-84sotgds	171	60	on	on	IN
cord-267965-84sotgds	171	61	influenza	influenza	NN
cord-267965-84sotgds	171	62	-	-	HYPH
cord-267965-84sotgds	171	63	induced	induce	VBN
cord-267965-84sotgds	171	64	weight	weight	NN
cord-267965-84sotgds	171	65	loss	loss	NN
cord-267965-84sotgds	171	66	)	)	-RRB-
cord-267965-84sotgds	171	67	.	.	.
cord-267965-84sotgds	172	1	Authors	author	NNS
cord-267965-84sotgds	172	2	have	have	VBP
cord-267965-84sotgds	172	3	narrowed	narrow	VBN
cord-267965-84sotgds	172	4	many	many	JJ
cord-267965-84sotgds	172	5	of	of	IN
cord-267965-84sotgds	172	6	these	these	DT
cord-267965-84sotgds	172	7	QTLs	qtl	NNS
cord-267965-84sotgds	172	8	to	to	IN
cord-267965-84sotgds	172	9	lists	list	NNS
cord-267965-84sotgds	172	10	of	of	IN
cord-267965-84sotgds	172	11	candidate	candidate	NN
cord-267965-84sotgds	172	12	genes	gene	NNS
cord-267965-84sotgds	172	13	,	,	,
cord-267965-84sotgds	172	14	and	and	CC
cord-267965-84sotgds	172	15	a	a	DT
cord-267965-84sotgds	172	16	small	small	JJ
cord-267965-84sotgds	172	17	number	number	NN
cord-267965-84sotgds	172	18	of	of	IN
cord-267965-84sotgds	172	19	these	these	DT
cord-267965-84sotgds	172	20	candidates	candidate	NNS
cord-267965-84sotgds	172	21	have	have	VBP
cord-267965-84sotgds	172	22	been	be	VBN
cord-267965-84sotgds	172	23	subsequently	subsequently	RB
cord-267965-84sotgds	172	24	validated	validate	VBN
cord-267965-84sotgds	172	25	.	.	.
cord-267965-84sotgds	173	1	To	to	IN
cord-267965-84sotgds	173	2	date	date	NN
cord-267965-84sotgds	173	3	,	,	,
cord-267965-84sotgds	173	4	most	most	JJS
cord-267965-84sotgds	173	5	publications	publication	NNS
cord-267965-84sotgds	173	6	have	have	VBP
cord-267965-84sotgds	173	7	highlighted	highlight	VBN
cord-267965-84sotgds	173	8	QTLs	qtls	NN
cord-267965-84sotgds	173	9	mapped	map	VBN
cord-267965-84sotgds	173	10	by	by	IN
cord-267965-84sotgds	173	11	phenotyping	phenotype	VBG
cord-267965-84sotgds	173	12	large	large	JJ
cord-267965-84sotgds	173	13	panels	panel	NNS
cord-267965-84sotgds	173	14	of	of	IN
cord-267965-84sotgds	173	15	CC	cc	NN
cord-267965-84sotgds	173	16	strains	strain	NNS
cord-267965-84sotgds	173	17	;	;	:
cord-267965-84sotgds	173	18	however	however	RB
cord-267965-84sotgds	173	19	,	,	,
cord-267965-84sotgds	173	20	this	this	DT
cord-267965-84sotgds	173	21	is	be	VBZ
cord-267965-84sotgds	173	22	not	not	RB
cord-267965-84sotgds	173	23	the	the	DT
cord-267965-84sotgds	173	24	only	only	JJ
cord-267965-84sotgds	173	25	successful	successful	JJ
cord-267965-84sotgds	173	26	strategy	strategy	NN
cord-267965-84sotgds	173	27	.	.	.
cord-267965-84sotgds	174	1	As	as	IN
cord-267965-84sotgds	174	2	mentioned	mention	VBN
cord-267965-84sotgds	174	3	above	above	RB
cord-267965-84sotgds	174	4	,	,	,
cord-267965-84sotgds	174	5	some	some	DT
cord-267965-84sotgds	174	6	CC	cc	NN
cord-267965-84sotgds	174	7	strains	strain	NNS
cord-267965-84sotgds	174	8	present	present	JJ
cord-267965-84sotgds	174	9	with	with	IN
cord-267965-84sotgds	174	10	unique	unique	JJ
cord-267965-84sotgds	174	11	disease	disease	NN
cord-267965-84sotgds	174	12	phenotypes	phenotype	NNS
cord-267965-84sotgds	174	13	,	,	,
cord-267965-84sotgds	174	14	which	which	WDT
cord-267965-84sotgds	174	15	may	may	MD
cord-267965-84sotgds	174	16	be	be	VB
cord-267965-84sotgds	174	17	driven	drive	VBN
cord-267965-84sotgds	174	18	by	by	IN
cord-267965-84sotgds	174	19	complex	complex	JJ
cord-267965-84sotgds	174	20	genetic	genetic	JJ
cord-267965-84sotgds	174	21	regulatory	regulatory	JJ
cord-267965-84sotgds	174	22	networks	network	NNS
cord-267965-84sotgds	174	23	involving	involve	VBG
cord-267965-84sotgds	174	24	multiple	multiple	JJ
cord-267965-84sotgds	174	25	loci	locus	NNS
cord-267965-84sotgds	174	26	with	with	IN
cord-267965-84sotgds	174	27	epistatic	epistatic	JJ
cord-267965-84sotgds	174	28	interactions	interaction	NNS
cord-267965-84sotgds	174	29	.	.	.
cord-267965-84sotgds	175	1	When	when	WRB
cord-267965-84sotgds	175	2	one	one	CD
cord-267965-84sotgds	175	3	or	or	CC
cord-267965-84sotgds	175	4	a	a	DT
cord-267965-84sotgds	175	5	few	few	JJ
cord-267965-84sotgds	175	6	CC	cc	NN
cord-267965-84sotgds	175	7	strains	strain	NNS
cord-267965-84sotgds	175	8	possess	possess	VBP
cord-267965-84sotgds	175	9	the	the	DT
cord-267965-84sotgds	175	10	combination	combination	NN
cord-267965-84sotgds	175	11	of	of	IN
cord-267965-84sotgds	175	12	genetic	genetic	JJ
cord-267965-84sotgds	175	13	variants	variant	NNS
cord-267965-84sotgds	175	14	needed	need	VBN
cord-267965-84sotgds	175	15	to	to	TO
cord-267965-84sotgds	175	16	manifest	manifest	VB
cord-267965-84sotgds	175	17	the	the	DT
cord-267965-84sotgds	175	18	novel	novel	JJ
cord-267965-84sotgds	175	19	phenotype	phenotype	NN
cord-267965-84sotgds	175	20	,	,	,
cord-267965-84sotgds	175	21	population	population	NN
cord-267965-84sotgds	175	22	-	-	HYPH
cord-267965-84sotgds	175	23	wide	wide	JJ
cord-267965-84sotgds	175	24	studies	study	NNS
cord-267965-84sotgds	175	25	may	may	MD
cord-267965-84sotgds	175	26	not	not	RB
cord-267965-84sotgds	175	27	possess	possess	VB
cord-267965-84sotgds	175	28	sufficient	sufficient	JJ
cord-267965-84sotgds	175	29	mapping	mapping	NN
cord-267965-84sotgds	175	30	power	power	NN
cord-267965-84sotgds	175	31	.	.	.
cord-267965-84sotgds	176	1	In	in	IN
cord-267965-84sotgds	176	2	these	these	DT
cord-267965-84sotgds	176	3	cases	case	NNS
cord-267965-84sotgds	176	4	,	,	,
cord-267965-84sotgds	176	5	researchers	researcher	NNS
cord-267965-84sotgds	176	6	have	have	VBP
cord-267965-84sotgds	176	7	successfully	successfully	RB
cord-267965-84sotgds	176	8	used	use	VBN
cord-267965-84sotgds	176	9	more	more	JJR
cord-267965-84sotgds	176	10	traditional	traditional	JJ
cord-267965-84sotgds	176	11	F2	f2	NN
cord-267965-84sotgds	176	12	or	or	CC
cord-267965-84sotgds	176	13	backcross	backcross	JJ
cord-267965-84sotgds	176	14	approaches	approach	NNS
cord-267965-84sotgds	176	15	to	to	TO
cord-267965-84sotgds	176	16	identify	identify	VB
cord-267965-84sotgds	176	17	causal	causal	JJ
cord-267965-84sotgds	176	18	genes	gene	NNS
cord-267965-84sotgds	176	19	(	(	-LRB-
cord-267965-84sotgds	176	20	Rogala	Rogala	NNP
cord-267965-84sotgds	176	21	et	et	FW
cord-267965-84sotgds	176	22	al	al	NNP
cord-267965-84sotgds	176	23	.	.	NNP
cord-267965-84sotgds	176	24	,	,	,
cord-267965-84sotgds	176	25	2014	2014	CD
cord-267965-84sotgds	176	26	)	)	-RRB-
cord-267965-84sotgds	176	27	.	.	.
cord-267965-84sotgds	177	1	In	in	IN
cord-267965-84sotgds	177	2	this	this	DT
cord-267965-84sotgds	177	3	section	section	NN
cord-267965-84sotgds	177	4	,	,	,
cord-267965-84sotgds	177	5	we	-PRON-	PRP
cord-267965-84sotgds	177	6	will	will	MD
cord-267965-84sotgds	177	7	highlight	highlight	VB
cord-267965-84sotgds	177	8	results	result	NNS
cord-267965-84sotgds	177	9	of	of	IN
cord-267965-84sotgds	177	10	both	both	DT
cord-267965-84sotgds	177	11	population	population	NN
cord-267965-84sotgds	177	12	-	-	HYPH
cord-267965-84sotgds	177	13	wide	wide	RB
cord-267965-84sotgds	177	14	and	and	CC
cord-267965-84sotgds	177	15	intercrossmediated	intercrossmediated	JJ
cord-267965-84sotgds	177	16	CC	CC	NNP
cord-267965-84sotgds	177	17	studies	study	NNS
cord-267965-84sotgds	177	18	of	of	IN
cord-267965-84sotgds	177	19	relevance	relevance	NN
cord-267965-84sotgds	177	20	to	to	IN
cord-267965-84sotgds	177	21	infectious	infectious	JJ
cord-267965-84sotgds	177	22	disease	disease	NN
cord-267965-84sotgds	177	23	research	research	NN
cord-267965-84sotgds	177	24	.	.	.
cord-267965-84sotgds	178	1	The	the	DT
cord-267965-84sotgds	178	2	first	first	JJ
cord-267965-84sotgds	178	3	host	host	NN
cord-267965-84sotgds	178	4	-	-	HYPH
cord-267965-84sotgds	178	5	pathogen	pathogen	NN
cord-267965-84sotgds	178	6	study	study	NN
cord-267965-84sotgds	178	7	in	in	IN
cord-267965-84sotgds	178	8	the	the	DT
cord-267965-84sotgds	178	9	CC	CC	NNP
cord-267965-84sotgds	178	10	examined	examine	VBD
cord-267965-84sotgds	178	11	susceptibility	susceptibility	NN
cord-267965-84sotgds	178	12	to	to	IN
cord-267965-84sotgds	178	13	the	the	DT
cord-267965-84sotgds	178	14	fungus	fungus	NN
cord-267965-84sotgds	178	15	Aspergillus	aspergillus	NN
cord-267965-84sotgds	178	16	fumigatus	fumigatus	NN
cord-267965-84sotgds	178	17	,	,	,
cord-267965-84sotgds	178	18	which	which	WDT
cord-267965-84sotgds	178	19	is	be	VBZ
cord-267965-84sotgds	178	20	pathogenic	pathogenic	JJ
cord-267965-84sotgds	178	21	in	in	IN
cord-267965-84sotgds	178	22	immunocompromised	immunocompromised	JJ
cord-267965-84sotgds	178	23	individuals	individual	NNS
cord-267965-84sotgds	178	24	.	.	.
cord-267965-84sotgds	179	1	Durrant	Durrant	NNP
cord-267965-84sotgds	179	2	et	et	NNP
cord-267965-84sotgds	179	3	al	al	NNP
cord-267965-84sotgds	179	4	.	.	.
cord-267965-84sotgds	180	1	found	find	VBD
cord-267965-84sotgds	180	2	that	that	IN
cord-267965-84sotgds	180	3	survival	survival	NN
cord-267965-84sotgds	180	4	time	time	NN
cord-267965-84sotgds	180	5	varied	vary	VBN
cord-267965-84sotgds	180	6	between	between	IN
cord-267965-84sotgds	180	7	4	4	CD
cord-267965-84sotgds	180	8	days	day	NNS
cord-267965-84sotgds	180	9	and	and	CC
cord-267965-84sotgds	180	10	over	over	IN
cord-267965-84sotgds	180	11	28	28	CD
cord-267965-84sotgds	180	12	days	day	NNS
cord-267965-84sotgds	180	13	post	post	NN
cord-267965-84sotgds	180	14	-	-	NN
cord-267965-84sotgds	180	15	infection	infection	NN
cord-267965-84sotgds	180	16	in	in	IN
cord-267965-84sotgds	180	17	66	66	CD
cord-267965-84sotgds	180	18	pre	pre	JJ
cord-267965-84sotgds	180	19	-	-	JJ
cord-267965-84sotgds	180	20	CC	cc	JJ
cord-267965-84sotgds	180	21	lines	line	NNS
cord-267965-84sotgds	180	22	(	(	-LRB-
cord-267965-84sotgds	180	23	Durrant	Durrant	NNP
cord-267965-84sotgds	180	24	et	et	NNP
cord-267965-84sotgds	180	25	al	al	NNP
cord-267965-84sotgds	180	26	.	.	NNP
cord-267965-84sotgds	180	27	,	,	,
cord-267965-84sotgds	180	28	2011	2011	CD
cord-267965-84sotgds	180	29	)	)	-RRB-
cord-267965-84sotgds	180	30	.	.	.
cord-267965-84sotgds	181	1	The	the	DT
cord-267965-84sotgds	181	2	authors	author	NNS
cord-267965-84sotgds	181	3	mapped	map	VBD
cord-267965-84sotgds	181	4	multiple	multiple	JJ
cord-267965-84sotgds	181	5	genome	genome	NN
cord-267965-84sotgds	181	6	-	-	HYPH
cord-267965-84sotgds	181	7	wide	wide	JJ
cord-267965-84sotgds	181	8	significant	significant	JJ
cord-267965-84sotgds	181	9	QTLs	qtl	NNS
cord-267965-84sotgds	181	10	for	for	IN
cord-267965-84sotgds	181	11	survival	survival	NN
cord-267965-84sotgds	181	12	time	time	NN
cord-267965-84sotgds	181	13	that	that	WDT
cord-267965-84sotgds	181	14	were	be	VBD
cord-267965-84sotgds	181	15	largely	largely	RB
cord-267965-84sotgds	181	16	driven	drive	VBN
cord-267965-84sotgds	181	17	by	by	IN
cord-267965-84sotgds	181	18	wild	wild	NN
cord-267965-84sotgds	181	19	-	-	HYPH
cord-267965-84sotgds	181	20	derived	derive	VBN
cord-267965-84sotgds	181	21	founder	founder	NN
cord-267965-84sotgds	181	22	haplotypes	haplotype	NNS
cord-267965-84sotgds	181	23	.	.	.
cord-267965-84sotgds	182	1	Candidate	candidate	NN
cord-267965-84sotgds	182	2	genes	gene	NNS
cord-267965-84sotgds	182	3	were	be	VBD
cord-267965-84sotgds	182	4	identified	identify	VBN
cord-267965-84sotgds	182	5	using	use	VBG
cord-267965-84sotgds	182	6	merge	merge	VB
cord-267965-84sotgds	182	7	analysis	analysis	NN
cord-267965-84sotgds	182	8	,	,	,
cord-267965-84sotgds	182	9	a	a	DT
cord-267965-84sotgds	182	10	procedure	procedure	NN
cord-267965-84sotgds	182	11	that	that	WDT
cord-267965-84sotgds	182	12	compares	compare	VBZ
cord-267965-84sotgds	182	13	the	the	DT
cord-267965-84sotgds	182	14	pattern	pattern	NN
cord-267965-84sotgds	182	15	of	of	IN
cord-267965-84sotgds	182	16	sequence	sequence	NN
cord-267965-84sotgds	182	17	variants	variant	NNS
cord-267965-84sotgds	182	18	(	(	-LRB-
cord-267965-84sotgds	182	19	e.g.	e.g.	RB
cord-267965-84sotgds	182	20	,	,	,
cord-267965-84sotgds	182	21	SNPs	SNPs	NNPS
cord-267965-84sotgds	182	22	or	or	CC
cord-267965-84sotgds	182	23	indels	indel	NNS
cord-267965-84sotgds	182	24	)	)	-RRB-
cord-267965-84sotgds	182	25	to	to	IN
cord-267965-84sotgds	182	26	the	the	DT
cord-267965-84sotgds	182	27	pattern	pattern	NN
cord-267965-84sotgds	182	28	of	of	IN
cord-267965-84sotgds	182	29	haplotype	haplotype	NN
cord-267965-84sotgds	182	30	effects	effect	NNS
cord-267965-84sotgds	182	31	(	(	-LRB-
cord-267965-84sotgds	182	32	impact	impact	NN
cord-267965-84sotgds	182	33	of	of	IN
cord-267965-84sotgds	182	34	each	each	DT
cord-267965-84sotgds	182	35	founder	founder	NN
cord-267965-84sotgds	182	36	strain	strain	NN
cord-267965-84sotgds	182	37	haplotype	haplotype	NN
cord-267965-84sotgds	182	38	on	on	IN
cord-267965-84sotgds	182	39	the	the	DT
cord-267965-84sotgds	182	40	phenotype	phenotype	NN
cord-267965-84sotgds	182	41	)	)	-RRB-
cord-267965-84sotgds	182	42	observed	observe	VBN
cord-267965-84sotgds	182	43	under	under	IN
cord-267965-84sotgds	182	44	the	the	DT
cord-267965-84sotgds	182	45	QTL	QTL	NNP
cord-267965-84sotgds	182	46	(	(	-LRB-
cord-267965-84sotgds	182	47	Yalcin	Yalcin	NNP
cord-267965-84sotgds	182	48	et	et	FW
cord-267965-84sotgds	182	49	al	al	NNP
cord-267965-84sotgds	182	50	.	.	NNP
cord-267965-84sotgds	182	51	,	,	,
cord-267965-84sotgds	182	52	2005	2005	CD
cord-267965-84sotgds	182	53	)	)	-RRB-
cord-267965-84sotgds	182	54	.	.	.
cord-267965-84sotgds	183	1	The	the	DT
cord-267965-84sotgds	183	2	application	application	NN
cord-267965-84sotgds	183	3	of	of	IN
cord-267965-84sotgds	183	4	merge	merge	VB
cord-267965-84sotgds	183	5	analysis	analysis	NN
cord-267965-84sotgds	183	6	to	to	IN
cord-267965-84sotgds	183	7	the	the	DT
cord-267965-84sotgds	183	8	CC	CC	NNP
cord-267965-84sotgds	183	9	enables	enable	VBZ
cord-267965-84sotgds	183	10	more	more	JJR
cord-267965-84sotgds	183	11	effective	effective	JJ
cord-267965-84sotgds	183	12	gene	gene	NN
cord-267965-84sotgds	183	13	refinement	refinement	NN
cord-267965-84sotgds	183	14	compared	compare	VBN
cord-267965-84sotgds	183	15	to	to	IN
cord-267965-84sotgds	183	16	studies	study	NNS
cord-267965-84sotgds	183	17	in	in	IN
cord-267965-84sotgds	183	18	classic	classic	JJ
cord-267965-84sotgds	183	19	biparental	biparental	NNP
cord-267965-84sotgds	183	20	GRPs	GRPs	NNP
cord-267965-84sotgds	183	21	,	,	,
cord-267965-84sotgds	183	22	where	where	WRB
cord-267965-84sotgds	183	23	the	the	DT
cord-267965-84sotgds	183	24	presence	presence	NN
cord-267965-84sotgds	183	25	of	of	IN
cord-267965-84sotgds	183	26	only	only	RB
cord-267965-84sotgds	183	27	two	two	CD
cord-267965-84sotgds	183	28	haplotypes	haplotype	NNS
cord-267965-84sotgds	183	29	means	mean	VBZ
cord-267965-84sotgds	183	30	that	that	IN
cord-267965-84sotgds	183	31	every	every	DT
cord-267965-84sotgds	183	32	genetic	genetic	JJ
cord-267965-84sotgds	183	33	variant	variant	NN
cord-267965-84sotgds	183	34	in	in	IN
cord-267965-84sotgds	183	35	a	a	DT
cord-267965-84sotgds	183	36	locus	locus	NN
cord-267965-84sotgds	183	37	is	be	VBZ
cord-267965-84sotgds	183	38	a	a	DT
cord-267965-84sotgds	183	39	putative	putative	JJ
cord-267965-84sotgds	183	40	candidate	candidate	NN
cord-267965-84sotgds	183	41	causal	causal	NN
cord-267965-84sotgds	183	42	variant	variant	NN
cord-267965-84sotgds	183	43	.	.	.
cord-267965-84sotgds	184	1	Merge	merge	VB
cord-267965-84sotgds	184	2	analysis	analysis	NN
cord-267965-84sotgds	184	3	supported	support	VBD
cord-267965-84sotgds	184	4	the	the	DT
cord-267965-84sotgds	184	5	candidate	candidate	NN
cord-267965-84sotgds	184	6	gene	gene	NN
cord-267965-84sotgds	184	7	Irf2	Irf2	NNP
cord-267965-84sotgds	184	8	,	,	,
cord-267965-84sotgds	184	9	an	an	DT
cord-267965-84sotgds	184	10	interferon	interferon	NN
cord-267965-84sotgds	184	11	regulatory	regulatory	JJ
cord-267965-84sotgds	184	12	transcriptional	transcriptional	JJ
cord-267965-84sotgds	184	13	factor	factor	NN
cord-267965-84sotgds	184	14	gene	gene	NN
cord-267965-84sotgds	184	15	,	,	,
cord-267965-84sotgds	184	16	under	under	IN
cord-267965-84sotgds	184	17	the	the	DT
cord-267965-84sotgds	184	18	most	most	RBS
cord-267965-84sotgds	184	19	significant	significant	JJ
cord-267965-84sotgds	184	20	QTL	qtl	NN
cord-267965-84sotgds	184	21	;	;	:
cord-267965-84sotgds	184	22	however	however	RB
cord-267965-84sotgds	184	23	,	,	,
cord-267965-84sotgds	184	24	for	for	IN
cord-267965-84sotgds	184	25	the	the	DT
cord-267965-84sotgds	184	26	remaining	remain	VBG
cord-267965-84sotgds	184	27	QTLs	qtl	NNS
cord-267965-84sotgds	184	28	there	there	EX
cord-267965-84sotgds	184	29	was	be	VBD
cord-267965-84sotgds	184	30	no	no	DT
cord-267965-84sotgds	184	31	strong	strong	JJ
cord-267965-84sotgds	184	32	concordance	concordance	NN
cord-267965-84sotgds	184	33	between	between	IN
cord-267965-84sotgds	184	34	a	a	DT
cord-267965-84sotgds	184	35	priori	priori	JJ
cord-267965-84sotgds	184	36	and	and	CC
cord-267965-84sotgds	184	37	merge	merge	VB
cord-267965-84sotgds	184	38	-	-	HYPH
cord-267965-84sotgds	184	39	supported	support	VBN
cord-267965-84sotgds	184	40	candidates	candidate	NNS
cord-267965-84sotgds	184	41	.	.	.
cord-267965-84sotgds	185	1	Klebsiella	Klebsiella	NNP
cord-267965-84sotgds	185	2	pneumoniae	pneumoniae	NN
cord-267965-84sotgds	185	3	Vered	Vered	NNP
cord-267965-84sotgds	185	4	et	et	NNP
cord-267965-84sotgds	185	5	al	al	NNP
cord-267965-84sotgds	185	6	.	.	.
cord-267965-84sotgds	185	7	challenged	challenge	VBD
cord-267965-84sotgds	185	8	73	73	CD
cord-267965-84sotgds	185	9	pre	pre	JJ
cord-267965-84sotgds	185	10	-	-	JJ
cord-267965-84sotgds	185	11	CC	cc	JJ
cord-267965-84sotgds	185	12	lines	line	NNS
cord-267965-84sotgds	185	13	with	with	IN
cord-267965-84sotgds	185	14	K.	K.	NNP
cord-267965-84sotgds	185	15	pneuomonia	pneuomonia	NNP
cord-267965-84sotgds	185	16	,	,	,
cord-267965-84sotgds	185	17	which	which	WDT
cord-267965-84sotgds	185	18	causes	cause	VBZ
cord-267965-84sotgds	185	19	severe	severe	JJ
cord-267965-84sotgds	185	20	pneumonia	pneumonia	NN
cord-267965-84sotgds	185	21	and	and	CC
cord-267965-84sotgds	185	22	sepsis	sepsis	NN
cord-267965-84sotgds	185	23	in	in	IN
cord-267965-84sotgds	185	24	immunocompromised	immunocompromised	JJ
cord-267965-84sotgds	185	25	individuals	individual	NNS
cord-267965-84sotgds	185	26	(	(	-LRB-
cord-267965-84sotgds	186	1	Vered	Vered	NNP
cord-267965-84sotgds	186	2	et	et	NNP
cord-267965-84sotgds	186	3	al	al	NNP
cord-267965-84sotgds	186	4	.	.	.
cord-267965-84sotgds	187	1	,	,	,
cord-267965-84sotgds	187	2	2014	2014	CD
cord-267965-84sotgds	187	3	)	)	-RRB-
cord-267965-84sotgds	187	4	.	.	.
cord-267965-84sotgds	188	1	The	the	DT
cord-267965-84sotgds	188	2	pre	pre	JJ
cord-267965-84sotgds	188	3	-	-	JJ
cord-267965-84sotgds	188	4	CC	cc	JJ
cord-267965-84sotgds	188	5	mice	mouse	NNS
cord-267965-84sotgds	188	6	displayed	display	VBD
cord-267965-84sotgds	188	7	broad	broad	JJ
cord-267965-84sotgds	188	8	and	and	CC
cord-267965-84sotgds	188	9	heritable	heritable	JJ
cord-267965-84sotgds	188	10	variation	variation	NN
cord-267965-84sotgds	188	11	in	in	IN
cord-267965-84sotgds	188	12	survival	survival	NN
cord-267965-84sotgds	188	13	time	time	NN
cord-267965-84sotgds	188	14	exceeding	exceed	VBG
cord-267965-84sotgds	188	15	that	that	WDT
cord-267965-84sotgds	188	16	observed	observe	VBD
cord-267965-84sotgds	188	17	in	in	IN
cord-267965-84sotgds	188	18	classic	classic	JJ
cord-267965-84sotgds	188	19	inbred	inbred	JJ
cord-267965-84sotgds	188	20	strains	strain	NNS
cord-267965-84sotgds	188	21	,	,	,
cord-267965-84sotgds	188	22	as	as	RB
cord-267965-84sotgds	188	23	well	well	RB
cord-267965-84sotgds	188	24	as	as	IN
cord-267965-84sotgds	188	25	dissociation	dissociation	NN
cord-267965-84sotgds	188	26	of	of	IN
cord-267965-84sotgds	188	27	survival	survival	NN
cord-267965-84sotgds	188	28	time	time	NN
cord-267965-84sotgds	188	29	from	from	IN
cord-267965-84sotgds	188	30	temperature	temperature	NN
cord-267965-84sotgds	188	31	or	or	CC
cord-267965-84sotgds	188	32	body	body	NN
cord-267965-84sotgds	188	33	weight	weight	NN
cord-267965-84sotgds	188	34	changes	change	NNS
cord-267965-84sotgds	188	35	.	.	.
cord-267965-84sotgds	189	1	The	the	DT
cord-267965-84sotgds	189	2	study	study	NN
cord-267965-84sotgds	189	3	identified	identify	VBD
cord-267965-84sotgds	189	4	one	one	CD
cord-267965-84sotgds	189	5	QTL	QTL	NNP
cord-267965-84sotgds	189	6	at	at	IN
cord-267965-84sotgds	189	7	day	day	NN
cord-267965-84sotgds	189	8	2	2	CD
cord-267965-84sotgds	189	9	post	post	NN
cord-267965-84sotgds	189	10	-	-	NN
cord-267965-84sotgds	189	11	infection	infection	NN
cord-267965-84sotgds	189	12	and	and	CC
cord-267965-84sotgds	189	13	two	two	CD
cord-267965-84sotgds	189	14	at	at	IN
cord-267965-84sotgds	189	15	day	day	NN
cord-267965-84sotgds	189	16	8	8	CD
cord-267965-84sotgds	189	17	post	post	NN
cord-267965-84sotgds	189	18	-	-	NN
cord-267965-84sotgds	189	19	infection	infection	NN
cord-267965-84sotgds	189	20	.	.	.
cord-267965-84sotgds	190	1	The	the	DT
cord-267965-84sotgds	190	2	authors	author	NNS
cord-267965-84sotgds	190	3	used	use	VBD
cord-267965-84sotgds	190	4	merge	merge	VB
cord-267965-84sotgds	190	5	analysis	analysis	NN
cord-267965-84sotgds	190	6	to	to	TO
cord-267965-84sotgds	190	7	refine	refine	VB
cord-267965-84sotgds	190	8	candidate	candidate	NN
cord-267965-84sotgds	190	9	genes	gene	NNS
cord-267965-84sotgds	190	10	;	;	:
cord-267965-84sotgds	190	11	however	however	RB
cord-267965-84sotgds	190	12	,	,	,
cord-267965-84sotgds	190	13	they	-PRON-	PRP
cord-267965-84sotgds	190	14	found	find	VBD
cord-267965-84sotgds	190	15	that	that	IN
cord-267965-84sotgds	190	16	the	the	DT
cord-267965-84sotgds	190	17	best	good	JJS
cord-267965-84sotgds	190	18	merge	merge	NN
cord-267965-84sotgds	190	19	candidates	candidate	NNS
cord-267965-84sotgds	190	20	showed	show	VBD
cord-267965-84sotgds	190	21	simpler	simple	JJR
cord-267965-84sotgds	190	22	allele	allele	NN
cord-267965-84sotgds	190	23	effect	effect	NN
cord-267965-84sotgds	190	24	patterns	pattern	NNS
cord-267965-84sotgds	190	25	than	than	IN
cord-267965-84sotgds	190	26	the	the	DT
cord-267965-84sotgds	190	27	more	more	RBR
cord-267965-84sotgds	190	28	complex	complex	JJ
cord-267965-84sotgds	190	29	haplotype	haplotype	NN
cord-267965-84sotgds	190	30	effects	effect	NNS
cord-267965-84sotgds	190	31	observed	observe	VBN
cord-267965-84sotgds	190	32	under	under	IN
cord-267965-84sotgds	190	33	the	the	DT
cord-267965-84sotgds	190	34	QTL	QTL	NNP
cord-267965-84sotgds	190	35	.	.	.
cord-267965-84sotgds	191	1	The	the	DT
cord-267965-84sotgds	191	2	strongest	strong	JJS
cord-267965-84sotgds	191	3	candidate	candidate	NN
cord-267965-84sotgds	191	4	genes	gene	NNS
cord-267965-84sotgds	191	5	identified	identify	VBN
cord-267965-84sotgds	191	6	were	be	VBD
cord-267965-84sotgds	191	7	Ikbkap	Ikbkap	NNP
cord-267965-84sotgds	191	8	,	,	,
cord-267965-84sotgds	191	9	a	a	DT
cord-267965-84sotgds	191	10	transcriptional	transcriptional	JJ
cord-267965-84sotgds	191	11	elongation	elongation	NN
cord-267965-84sotgds	191	12	factor	factor	NN
cord-267965-84sotgds	191	13	complex	complex	JJ
cord-267965-84sotgds	191	14	component	component	NN
cord-267965-84sotgds	191	15	,	,	,
cord-267965-84sotgds	191	16	and	and	CC
cord-267965-84sotgds	191	17	Actl7a	Actl7a	NNP
cord-267965-84sotgds	191	18	,	,	,
cord-267965-84sotgds	191	19	Actl7b	Actl7b	NNP
cord-267965-84sotgds	191	20	,	,	,
cord-267965-84sotgds	191	21	and	and	CC
cord-267965-84sotgds	191	22	Ctnnal1	Ctnnal1	NNP
cord-267965-84sotgds	191	23	,	,	,
cord-267965-84sotgds	191	24	which	which	WDT
cord-267965-84sotgds	191	25	are	be	VBP
cord-267965-84sotgds	191	26	involved	involve	VBN
cord-267965-84sotgds	191	27	in	in	IN
cord-267965-84sotgds	191	28	cell	cell	NN
cord-267965-84sotgds	191	29	adhesion	adhesion	NN
cord-267965-84sotgds	191	30	and	and	CC
cord-267965-84sotgds	191	31	cytoskeletal	cytoskeletal	JJ
cord-267965-84sotgds	191	32	structure	structure	NN
cord-267965-84sotgds	191	33	.	.	.
cord-267965-84sotgds	192	1	Bottomly	Bottomly	NNP
cord-267965-84sotgds	192	2	et	et	NNP
cord-267965-84sotgds	192	3	al	al	NNP
cord-267965-84sotgds	192	4	.	.	.
cord-267965-84sotgds	192	5	analyzed	analyze	VBD
cord-267965-84sotgds	192	6	a	a	DT
cord-267965-84sotgds	192	7	set	set	NN
cord-267965-84sotgds	192	8	of	of	IN
cord-267965-84sotgds	192	9	99	99	CD
cord-267965-84sotgds	192	10	pre	pre	JJ
cord-267965-84sotgds	192	11	-	-	JJ
cord-267965-84sotgds	192	12	CC	cc	JJ
cord-267965-84sotgds	192	13	lines	line	NNS
cord-267965-84sotgds	192	14	infected	infect	VBN
cord-267965-84sotgds	192	15	with	with	IN
cord-267965-84sotgds	192	16	mouse	mouse	NN
cord-267965-84sotgds	192	17	-	-	HYPH
cord-267965-84sotgds	192	18	adapted	adapt	VBN
cord-267965-84sotgds	192	19	influenza	influenza	NN
cord-267965-84sotgds	192	20	A	a	NN
cord-267965-84sotgds	192	21	/	/	SYM
cord-267965-84sotgds	192	22	PR/8/34	PR/8/34	NNP
cord-267965-84sotgds	192	23	and	and	CC
cord-267965-84sotgds	192	24	assessed	assess	VBD
cord-267965-84sotgds	192	25	weight	weight	NN
cord-267965-84sotgds	192	26	loss	loss	NN
cord-267965-84sotgds	192	27	,	,	,
cord-267965-84sotgds	192	28	clinical	clinical	JJ
cord-267965-84sotgds	192	29	score	score	NN
cord-267965-84sotgds	192	30	,	,	,
cord-267965-84sotgds	192	31	and	and	CC
cord-267965-84sotgds	192	32	mortality	mortality	NN
cord-267965-84sotgds	192	33	through	through	IN
cord-267965-84sotgds	192	34	4	4	CD
cord-267965-84sotgds	192	35	days	day	NNS
cord-267965-84sotgds	192	36	post	post	NN
cord-267965-84sotgds	192	37	-	-	NN
cord-267965-84sotgds	192	38	infection	infection	JJ
cord-267965-84sotgds	193	1	(	(	-LRB-
cord-267965-84sotgds	193	2	Bottomly	Bottomly	NNP
cord-267965-84sotgds	193	3	et	et	NNP
cord-267965-84sotgds	193	4	al	al	NNP
cord-267965-84sotgds	193	5	.	.	NNP
cord-267965-84sotgds	193	6	,	,	,
cord-267965-84sotgds	193	7	2012	2012	CD
cord-267965-84sotgds	193	8	)	)	-RRB-
cord-267965-84sotgds	193	9	.	.	.
cord-267965-84sotgds	194	1	A	a	DT
cord-267965-84sotgds	194	2	subset	subset	NN
cord-267965-84sotgds	194	3	of	of	IN
cord-267965-84sotgds	194	4	pre	pre	JJ
cord-267965-84sotgds	194	5	-	-	JJ
cord-267965-84sotgds	194	6	CC	cc	JJ
cord-267965-84sotgds	194	7	lines	line	NNS
cord-267965-84sotgds	194	8	,	,	,
cord-267965-84sotgds	194	9	classified	classify	VBN
cord-267965-84sotgds	194	10	as	as	IN
cord-267965-84sotgds	194	11	high	high	JJ
cord-267965-84sotgds	194	12	and	and	CC
cord-267965-84sotgds	194	13	low	low	JJ
cord-267965-84sotgds	194	14	responders	responder	NNS
cord-267965-84sotgds	194	15	based	base	VBN
cord-267965-84sotgds	194	16	on	on	IN
cord-267965-84sotgds	194	17	a	a	DT
cord-267965-84sotgds	194	18	composite	composite	JJ
cord-267965-84sotgds	194	19	metric	metric	NN
cord-267965-84sotgds	194	20	of	of	IN
cord-267965-84sotgds	194	21	weight	weight	NN
cord-267965-84sotgds	194	22	loss	loss	NN
cord-267965-84sotgds	194	23	and	and	CC
cord-267965-84sotgds	194	24	histopathological	histopathological	JJ
cord-267965-84sotgds	194	25	scoring	scoring	NN
cord-267965-84sotgds	194	26	,	,	,
cord-267965-84sotgds	194	27	were	be	VBD
cord-267965-84sotgds	194	28	selected	select	VBN
cord-267965-84sotgds	194	29	for	for	IN
cord-267965-84sotgds	194	30	transcriptomic	transcriptomic	JJ
cord-267965-84sotgds	194	31	profiling	profiling	NN
cord-267965-84sotgds	194	32	.	.	.
cord-267965-84sotgds	195	1	Over	over	IN
cord-267965-84sotgds	195	2	2,000	2,000	CD
cord-267965-84sotgds	195	3	transcripts	transcript	NNS
cord-267965-84sotgds	195	4	were	be	VBD
cord-267965-84sotgds	195	5	differentially	differentially	RB
cord-267965-84sotgds	195	6	expressed	express	VBN
cord-267965-84sotgds	195	7	between	between	IN
cord-267965-84sotgds	195	8	susceptible	susceptible	JJ
cord-267965-84sotgds	195	9	and	and	CC
cord-267965-84sotgds	195	10	resistant	resistant	JJ
cord-267965-84sotgds	195	11	classes	class	NNS
cord-267965-84sotgds	195	12	,	,	,
cord-267965-84sotgds	195	13	and	and	CC
cord-267965-84sotgds	195	14	mapping	mapping	NN
cord-267965-84sotgds	195	15	identified	identify	VBD
cord-267965-84sotgds	195	16	21	21	CD
cord-267965-84sotgds	195	17	significant	significant	JJ
cord-267965-84sotgds	195	18	expression	expression	NN
cord-267965-84sotgds	195	19	QTLs	QTLs	NNP
cord-267965-84sotgds	195	20	(	(	-LRB-
cord-267965-84sotgds	195	21	eQTLs	eqtls	NN
cord-267965-84sotgds	195	22	)	)	-RRB-
cord-267965-84sotgds	195	23	.	.	.
cord-267965-84sotgds	196	1	Twelve	twelve	CD
cord-267965-84sotgds	196	2	of	of	IN
cord-267965-84sotgds	196	3	the	the	DT
cord-267965-84sotgds	196	4	eQTLs	eqtls	NN
cord-267965-84sotgds	196	5	were	be	VBD
cord-267965-84sotgds	196	6	validated	validate	VBN
cord-267965-84sotgds	196	7	in	in	IN
cord-267965-84sotgds	196	8	CC	CC	NNP
cord-267965-84sotgds	196	9	founder	founder	NN
cord-267965-84sotgds	196	10	strains	strain	NNS
cord-267965-84sotgds	196	11	,	,	,
cord-267965-84sotgds	196	12	and	and	CC
cord-267965-84sotgds	196	13	structural	structural	JJ
cord-267965-84sotgds	196	14	equation	equation	NN
cord-267965-84sotgds	196	15	modeling	modeling	NN
cord-267965-84sotgds	196	16	was	be	VBD
cord-267965-84sotgds	196	17	applied	apply	VBN
cord-267965-84sotgds	196	18	to	to	IN
cord-267965-84sotgds	196	19	these	these	DT
cord-267965-84sotgds	196	20	candidates	candidate	NNS
cord-267965-84sotgds	196	21	to	to	TO
cord-267965-84sotgds	196	22	infer	infer	VB
cord-267965-84sotgds	196	23	reactive	reactive	JJ
cord-267965-84sotgds	196	24	expression	expression	NN
cord-267965-84sotgds	196	25	networks	network	NNS
cord-267965-84sotgds	196	26	underlying	underlie	VBG
cord-267965-84sotgds	196	27	the	the	DT
cord-267965-84sotgds	196	28	transcriptional	transcriptional	JJ
cord-267965-84sotgds	196	29	differences	difference	NNS
cord-267965-84sotgds	196	30	.	.	.
cord-267965-84sotgds	197	1	In	in	IN
cord-267965-84sotgds	197	2	a	a	DT
cord-267965-84sotgds	197	3	companion	companion	NN
cord-267965-84sotgds	197	4	study	study	NN
cord-267965-84sotgds	197	5	,	,	,
cord-267965-84sotgds	197	6	Ferris	Ferris	NNP
cord-267965-84sotgds	197	7	et	et	NNP
cord-267965-84sotgds	197	8	al	al	NNP
cord-267965-84sotgds	197	9	.	.	.
cord-267965-84sotgds	198	1	further	further	RB
cord-267965-84sotgds	198	2	characterized	characterize	VBN
cord-267965-84sotgds	198	3	variation	variation	NN
cord-267965-84sotgds	198	4	in	in	IN
cord-267965-84sotgds	198	5	response	response	NN
cord-267965-84sotgds	198	6	to	to	IN
cord-267965-84sotgds	198	7	influenza	influenza	VB
cord-267965-84sotgds	198	8	A	A	NNP
cord-267965-84sotgds	198	9	/	/	SYM
cord-267965-84sotgds	198	10	PR/8/34	pr/8/34	CD
cord-267965-84sotgds	198	11	in	in	IN
cord-267965-84sotgds	198	12	155	155	CD
cord-267965-84sotgds	198	13	pre	pre	JJ
cord-267965-84sotgds	198	14	-	-	JJ
cord-267965-84sotgds	198	15	CC	cc	JJ
cord-267965-84sotgds	198	16	lines	line	NNS
cord-267965-84sotgds	199	1	(	(	-LRB-
cord-267965-84sotgds	199	2	Ferris	Ferris	NNP
cord-267965-84sotgds	199	3	et	et	NNP
cord-267965-84sotgds	199	4	al	al	NNP
cord-267965-84sotgds	199	5	.	.	NNP
cord-267965-84sotgds	199	6	,	,	,
cord-267965-84sotgds	199	7	2013	2013	CD
cord-267965-84sotgds	199	8	)	)	-RRB-
cord-267965-84sotgds	199	9	.	.	.
cord-267965-84sotgds	200	1	While	while	IN
cord-267965-84sotgds	200	2	disease	disease	NN
cord-267965-84sotgds	200	3	-	-	HYPH
cord-267965-84sotgds	200	4	associated	associate	VBN
cord-267965-84sotgds	200	5	phenotypes	phenotype	NNS
cord-267965-84sotgds	200	6	(	(	-LRB-
cord-267965-84sotgds	200	7	weight	weight	NN
cord-267965-84sotgds	200	8	loss	loss	NN
cord-267965-84sotgds	200	9	,	,	,
cord-267965-84sotgds	200	10	viral	viral	JJ
cord-267965-84sotgds	200	11	titer	titer	NN
cord-267965-84sotgds	200	12	,	,	,
cord-267965-84sotgds	200	13	and	and	CC
cord-267965-84sotgds	200	14	inflammation	inflammation	NN
cord-267965-84sotgds	200	15	)	)	-RRB-
cord-267965-84sotgds	200	16	were	be	VBD
cord-267965-84sotgds	200	17	largely	largely	RB
cord-267965-84sotgds	200	18	correlated	correlate	VBN
cord-267965-84sotgds	200	19	,	,	,
cord-267965-84sotgds	200	20	subsets	subset	NNS
cord-267965-84sotgds	200	21	of	of	IN
cord-267965-84sotgds	200	22	these	these	DT
cord-267965-84sotgds	200	23	pre	pre	JJ
cord-267965-84sotgds	200	24	-	-	JJ
cord-267965-84sotgds	200	25	CC	cc	JJ
cord-267965-84sotgds	200	26	mice	mouse	NNS
cord-267965-84sotgds	200	27	showed	show	VBD
cord-267965-84sotgds	200	28	breakdowns	breakdown	NNS
cord-267965-84sotgds	200	29	in	in	IN
cord-267965-84sotgds	200	30	these	these	DT
cord-267965-84sotgds	200	31	relationships	relationship	NNS
cord-267965-84sotgds	200	32	,	,	,
cord-267965-84sotgds	200	33	resulting	result	VBG
cord-267965-84sotgds	200	34	in	in	IN
cord-267965-84sotgds	200	35	novel	novel	JJ
cord-267965-84sotgds	200	36	phenotypic	phenotypic	JJ
cord-267965-84sotgds	200	37	combinations	combination	NNS
cord-267965-84sotgds	200	38	not	not	RB
cord-267965-84sotgds	200	39	observed	observe	VBN
cord-267965-84sotgds	200	40	in	in	IN
cord-267965-84sotgds	200	41	classical	classical	JJ
cord-267965-84sotgds	200	42	mouse	mouse	NN
cord-267965-84sotgds	200	43	strains	strain	NNS
cord-267965-84sotgds	200	44	(	(	-LRB-
cord-267965-84sotgds	200	45	e.g.	e.g.	RB
cord-267965-84sotgds	200	46	,	,	,
cord-267965-84sotgds	200	47	high	high	JJ
cord-267965-84sotgds	200	48	weight	weight	NN
cord-267965-84sotgds	200	49	loss	loss	NN
cord-267965-84sotgds	200	50	with	with	IN
cord-267965-84sotgds	200	51	minimal	minimal	JJ
cord-267965-84sotgds	200	52	inflammation	inflammation	NN
cord-267965-84sotgds	200	53	)	)	-RRB-
cord-267965-84sotgds	200	54	.	.	.
cord-267965-84sotgds	201	1	This	this	DT
cord-267965-84sotgds	201	2	study	study	NN
cord-267965-84sotgds	201	3	identified	identify	VBD
cord-267965-84sotgds	201	4	four	four	CD
cord-267965-84sotgds	201	5	significant	significant	JJ
cord-267965-84sotgds	201	6	QTLs	qtl	NNS
cord-267965-84sotgds	201	7	,	,	,
cord-267965-84sotgds	201	8	including	include	VBG
cord-267965-84sotgds	201	9	one	one	CD
cord-267965-84sotgds	201	10	strong	strong	JJ
cord-267965-84sotgds	201	11	QTL	QTL	NNP
cord-267965-84sotgds	201	12	that	that	WDT
cord-267965-84sotgds	201	13	explained	explain	VBD
cord-267965-84sotgds	201	14	approximately	approximately	RB
cord-267965-84sotgds	201	15	42	42	CD
cord-267965-84sotgds	201	16	%	%	NN
cord-267965-84sotgds	201	17	of	of	IN
cord-267965-84sotgds	201	18	IAV	iav	NN
cord-267965-84sotgds	201	19	-	-	HYPH
cord-267965-84sotgds	201	20	induced	induce	VBN
cord-267965-84sotgds	201	21	weight	weight	NN
cord-267965-84sotgds	201	22	loss	loss	NN
cord-267965-84sotgds	201	23	,	,	,
cord-267965-84sotgds	201	24	over	over	IN
cord-267965-84sotgds	201	25	the	the	DT
cord-267965-84sotgds	201	26	IAV	IAV	NNP
cord-267965-84sotgds	201	27	resistance	resistance	NN
cord-267965-84sotgds	201	28	gene	gene	NN
cord-267965-84sotgds	201	29	Mx1	mx1	CD
cord-267965-84sotgds	201	30	.	.	.
cord-267965-84sotgds	202	1	Importantly	importantly	RB
cord-267965-84sotgds	202	2	,	,	,
cord-267965-84sotgds	202	3	while	while	IN
cord-267965-84sotgds	202	4	Mx1	mx1	JJ
cord-267965-84sotgds	202	5	is	be	VBZ
cord-267965-84sotgds	202	6	well	well	RB
cord-267965-84sotgds	202	7	studied	study	VBN
cord-267965-84sotgds	202	8	,	,	,
cord-267965-84sotgds	202	9	the	the	DT
cord-267965-84sotgds	202	10	authors	author	NNS
cord-267965-84sotgds	202	11	identified	identify	VBD
cord-267965-84sotgds	202	12	a	a	DT
cord-267965-84sotgds	202	13	novel	novel	JJ
cord-267965-84sotgds	202	14	allelic	allelic	JJ
cord-267965-84sotgds	202	15	variant	variant	NN
cord-267965-84sotgds	202	16	derived	derive	VBN
cord-267965-84sotgds	202	17	from	from	IN
cord-267965-84sotgds	202	18	CAST	cast	NN
cord-267965-84sotgds	202	19	/	/	SYM
cord-267965-84sotgds	202	20	EiJ	eij	NN
cord-267965-84sotgds	202	21	that	that	WDT
cord-267965-84sotgds	202	22	protects	protect	VBZ
cord-267965-84sotgds	202	23	from	from	IN
cord-267965-84sotgds	202	24	weight	weight	NN
cord-267965-84sotgds	202	25	loss	loss	NN
cord-267965-84sotgds	202	26	but	but	CC
cord-267965-84sotgds	202	27	less	less	RBR
cord-267965-84sotgds	202	28	efficiently	efficiently	RB
cord-267965-84sotgds	202	29	inhibits	inhibit	VBZ
cord-267965-84sotgds	202	30	viral	viral	JJ
cord-267965-84sotgds	202	31	replication	replication	NN
cord-267965-84sotgds	202	32	compared	compare	VBN
cord-267965-84sotgds	202	33	to	to	IN
cord-267965-84sotgds	202	34	the	the	DT
cord-267965-84sotgds	202	35	functional	functional	JJ
cord-267965-84sotgds	202	36	M.	M.	NNP
cord-267965-84sotgds	202	37	musculus	musculus	NN
cord-267965-84sotgds	202	38	musculus	musculus	NN
cord-267965-84sotgds	202	39	-	-	HYPH
cord-267965-84sotgds	202	40	derived	derive	VBN
cord-267965-84sotgds	202	41	allele	allele	NN
cord-267965-84sotgds	202	42	carried	carry	VBN
cord-267965-84sotgds	202	43	by	by	IN
cord-267965-84sotgds	202	44	NZO	NZO	NNP
cord-267965-84sotgds	202	45	/	/	SYM
cord-267965-84sotgds	202	46	HiLtJ	HiLtJ	NNP
cord-267965-84sotgds	202	47	and	and	CC
cord-267965-84sotgds	203	1	PWK	PWK	NNP
cord-267965-84sotgds	203	2	/	/	SYM
cord-267965-84sotgds	203	3	PhJ.	PhJ.	NNP
cord-267965-84sotgds	203	4	Consistent	Consistent	NNP
cord-267965-84sotgds	203	5	with	with	IN
cord-267965-84sotgds	203	6	Ferris	Ferris	NNP
cord-267965-84sotgds	203	7	et	et	NNP
cord-267965-84sotgds	203	8	al	al	NNP
cord-267965-84sotgds	203	9	.	.	NNP
cord-267965-84sotgds	203	10	's	's	POS
cord-267965-84sotgds	203	11	finding	finding	NN
cord-267965-84sotgds	203	12	of	of	IN
cord-267965-84sotgds	203	13	a	a	DT
cord-267965-84sotgds	203	14	uniquely	uniquely	RB
cord-267965-84sotgds	203	15	functional	functional	JJ
cord-267965-84sotgds	203	16	CAST	cast	NN
cord-267965-84sotgds	203	17	/	/	SYM
cord-267965-84sotgds	203	18	EiJ	eij	NN
cord-267965-84sotgds	203	19	Mx1	mx1	JJ
cord-267965-84sotgds	203	20	variant	variant	NN
cord-267965-84sotgds	203	21	,	,	,
cord-267965-84sotgds	203	22	Leist	Leist	NNP
cord-267965-84sotgds	203	23	et	et	FW
cord-267965-84sotgds	203	24	al	al	NNP
cord-267965-84sotgds	203	25	.	.	.
cord-267965-84sotgds	204	1	found	find	VBD
cord-267965-84sotgds	204	2	that	that	IN
cord-267965-84sotgds	204	3	CAST	cast	NN
cord-267965-84sotgds	204	4	/	/	SYM
cord-267965-84sotgds	204	5	EiJ	eij	NN
cord-267965-84sotgds	204	6	mice	mouse	NNS
cord-267965-84sotgds	204	7	have	have	VBP
cord-267965-84sotgds	204	8	a	a	DT
cord-267965-84sotgds	204	9	unique	unique	JJ
cord-267965-84sotgds	204	10	response	response	NN
cord-267965-84sotgds	204	11	to	to	IN
cord-267965-84sotgds	204	12	an	an	DT
cord-267965-84sotgds	204	13	H3N2	H3N2	NNP
cord-267965-84sotgds	204	14	strain	strain	NN
cord-267965-84sotgds	204	15	of	of	IN
cord-267965-84sotgds	204	16	IAV	IAV	NNP
cord-267965-84sotgds	205	1	(	(	-LRB-
cord-267965-84sotgds	205	2	Leist	Leist	NNP
cord-267965-84sotgds	205	3	et	et	FW
cord-267965-84sotgds	205	4	al	al	NNP
cord-267965-84sotgds	205	5	.	.	NNP
cord-267965-84sotgds	205	6	,	,	,
cord-267965-84sotgds	205	7	2016	2016	CD
cord-267965-84sotgds	205	8	)	)	-RRB-
cord-267965-84sotgds	205	9	.	.	.
cord-267965-84sotgds	206	1	While	while	IN
cord-267965-84sotgds	206	2	the	the	DT
cord-267965-84sotgds	206	3	Mx1	mx1	JJ
cord-267965-84sotgds	206	4	locus	locus	NN
cord-267965-84sotgds	206	5	had	have	VBD
cord-267965-84sotgds	206	6	a	a	DT
cord-267965-84sotgds	206	7	dominating	dominating	JJ
cord-267965-84sotgds	206	8	effect	effect	NN
cord-267965-84sotgds	206	9	in	in	IN
cord-267965-84sotgds	206	10	the	the	DT
cord-267965-84sotgds	206	11	Ferris	Ferris	NNP
cord-267965-84sotgds	206	12	et	et	NNP
cord-267965-84sotgds	206	13	al	al	NNP
cord-267965-84sotgds	206	14	.	.	NNP
cord-267965-84sotgds	206	15	study	study	NN
cord-267965-84sotgds	206	16	,	,	,
cord-267965-84sotgds	206	17	large	large	JJ
cord-267965-84sotgds	206	18	phenotypic	phenotypic	JJ
cord-267965-84sotgds	206	19	variation	variation	NN
cord-267965-84sotgds	206	20	occurred	occur	VBD
cord-267965-84sotgds	206	21	within	within	IN
cord-267965-84sotgds	206	22	Mx1	mx1	JJ
cord-267965-84sotgds	206	23	classes	class	NNS
cord-267965-84sotgds	206	24	,	,	,
cord-267965-84sotgds	206	25	suggesting	suggest	VBG
cord-267965-84sotgds	206	26	the	the	DT
cord-267965-84sotgds	206	27	presence	presence	NN
cord-267965-84sotgds	206	28	of	of	IN
cord-267965-84sotgds	206	29	modifier	modifier	NN
cord-267965-84sotgds	206	30	alleles	allele	NNS
cord-267965-84sotgds	206	31	.	.	.
cord-267965-84sotgds	207	1	Three	three	CD
cord-267965-84sotgds	207	2	additional	additional	JJ
cord-267965-84sotgds	207	3	QTLs	qtl	NNS
cord-267965-84sotgds	207	4	were	be	VBD
cord-267965-84sotgds	207	5	mapped	map	VBN
cord-267965-84sotgds	207	6	when	when	WRB
cord-267965-84sotgds	207	7	controlling	control	VBG
cord-267965-84sotgds	207	8	for	for	IN
cord-267965-84sotgds	207	9	Mx1	mx1	JJ
cord-267965-84sotgds	207	10	haplotype	haplotype	NN
cord-267965-84sotgds	207	11	,	,	,
cord-267965-84sotgds	207	12	corresponding	correspond	VBG
cord-267965-84sotgds	207	13	to	to	IN
cord-267965-84sotgds	207	14	variation	variation	NN
cord-267965-84sotgds	207	15	in	in	IN
cord-267965-84sotgds	207	16	weight	weight	NN
cord-267965-84sotgds	207	17	loss	loss	NN
cord-267965-84sotgds	207	18	,	,	,
cord-267965-84sotgds	207	19	pulmonary	pulmonary	JJ
cord-267965-84sotgds	207	20	edema	edema	NN
cord-267965-84sotgds	207	21	,	,	,
cord-267965-84sotgds	207	22	and	and	CC
cord-267965-84sotgds	207	23	airway	airway	JJ
cord-267965-84sotgds	207	24	neutrophils	neutrophil	NNS
cord-267965-84sotgds	207	25	.	.	.
cord-267965-84sotgds	208	1	Notably	notably	RB
cord-267965-84sotgds	208	2	,	,	,
cord-267965-84sotgds	208	3	aside	aside	RB
cord-267965-84sotgds	208	4	from	from	IN
cord-267965-84sotgds	208	5	the	the	DT
cord-267965-84sotgds	208	6	Mx1	mx1	JJ
cord-267965-84sotgds	208	7	locus	locus	NN
cord-267965-84sotgds	208	8	,	,	,
cord-267965-84sotgds	208	9	none	none	NN
cord-267965-84sotgds	208	10	of	of	IN
cord-267965-84sotgds	208	11	the	the	DT
cord-267965-84sotgds	208	12	QTLs	qtl	NNS
cord-267965-84sotgds	208	13	identified	identify	VBN
cord-267965-84sotgds	208	14	by	by	IN
cord-267965-84sotgds	208	15	Ferris	Ferris	NNP
cord-267965-84sotgds	208	16	et	et	NNP
cord-267965-84sotgds	208	17	al	al	NNP
cord-267965-84sotgds	208	18	.	.	.
cord-267965-84sotgds	209	1	matched	match	VBN
cord-267965-84sotgds	209	2	influenza	influenza	NN
cord-267965-84sotgds	209	3	susceptibility	susceptibility	NN
cord-267965-84sotgds	209	4	loci	locus	NNS
cord-267965-84sotgds	209	5	found	find	VBN
cord-267965-84sotgds	209	6	in	in	IN
cord-267965-84sotgds	209	7	mapping	mapping	NN
cord-267965-84sotgds	209	8	studies	study	NNS
cord-267965-84sotgds	209	9	conducted	conduct	VBN
cord-267965-84sotgds	209	10	in	in	IN
cord-267965-84sotgds	209	11	the	the	DT
cord-267965-84sotgds	209	12	BXD	BXD	NNP
cord-267965-84sotgds	209	13	population	population	NN
cord-267965-84sotgds	209	14	.	.	.
cord-267965-84sotgds	210	1	(	(	-LRB-
cord-267965-84sotgds	210	2	Boon	Boon	NNP
cord-267965-84sotgds	210	3	et	et	NNP
cord-267965-84sotgds	210	4	al	al	NNP
cord-267965-84sotgds	210	5	.	.	.
cord-267965-84sotgds	211	1	,	,	,
cord-267965-84sotgds	211	2	2009	2009	CD
cord-267965-84sotgds	211	3	;	;	:
cord-267965-84sotgds	211	4	Nedelko	Nedelko	NNP
cord-267965-84sotgds	211	5	et	et	NNP
cord-267965-84sotgds	211	6	al	al	NNP
cord-267965-84sotgds	211	7	.	.	NNP
cord-267965-84sotgds	211	8	,	,	,
cord-267965-84sotgds	211	9	2012	2012	CD
cord-267965-84sotgds	211	10	)	)	-RRB-
cord-267965-84sotgds	211	11	.	.	.
cord-267965-84sotgds	212	1	These	these	DT
cord-267965-84sotgds	212	2	differences	difference	NNS
cord-267965-84sotgds	212	3	may	may	MD
cord-267965-84sotgds	212	4	reflect	reflect	VB
cord-267965-84sotgds	212	5	the	the	DT
cord-267965-84sotgds	212	6	more	more	RBR
cord-267965-84sotgds	212	7	complex	complex	JJ
cord-267965-84sotgds	212	8	genetics	genetic	NNS
cord-267965-84sotgds	212	9	of	of	IN
cord-267965-84sotgds	212	10	the	the	DT
cord-267965-84sotgds	212	11	CC	CC	NNP
cord-267965-84sotgds	212	12	compared	compare	VBN
cord-267965-84sotgds	212	13	to	to	IN
cord-267965-84sotgds	212	14	the	the	DT
cord-267965-84sotgds	212	15	BXD	BXD	NNP
cord-267965-84sotgds	212	16	and/or	and/or	CC
cord-267965-84sotgds	212	17	differences	difference	NNS
cord-267965-84sotgds	212	18	in	in	IN
cord-267965-84sotgds	212	19	the	the	DT
cord-267965-84sotgds	212	20	strain	strain	NN
cord-267965-84sotgds	212	21	of	of	IN
cord-267965-84sotgds	212	22	influenza	influenza	NN
cord-267965-84sotgds	212	23	or	or	CC
cord-267965-84sotgds	212	24	other	other	JJ
cord-267965-84sotgds	212	25	experimental	experimental	JJ
cord-267965-84sotgds	212	26	variables	variable	NNS
cord-267965-84sotgds	212	27	across	across	IN
cord-267965-84sotgds	212	28	studies	study	NNS
cord-267965-84sotgds	212	29	.	.	.
cord-267965-84sotgds	213	1	Salmonella	Salmonella	NNP
cord-267965-84sotgds	213	2	enterica	enterica	NNP
cord-267965-84sotgds	214	1	Salmonella	Salmonella	NNP
cord-267965-84sotgds	214	2	enterica	enterica	NNP
cord-267965-84sotgds	214	3	serovar	serovar	NNP
cord-267965-84sotgds	214	4	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	214	5	(	(	-LRB-
cord-267965-84sotgds	214	6	S.	S.	NNP
cord-267965-84sotgds	214	7	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	214	8	)	)	-RRB-
cord-267965-84sotgds	214	9	causes	cause	VBZ
cord-267965-84sotgds	214	10	typhoid	typhoid	NN
cord-267965-84sotgds	214	11	fever	fever	NN
cord-267965-84sotgds	214	12	,	,	,
cord-267965-84sotgds	214	13	and	and	CC
cord-267965-84sotgds	214	14	previous	previous	JJ
cord-267965-84sotgds	214	15	mouse	mouse	NN
cord-267965-84sotgds	214	16	mapping	mapping	NN
cord-267965-84sotgds	214	17	studies	study	NNS
cord-267965-84sotgds	214	18	have	have	VBP
cord-267965-84sotgds	214	19	identified	identify	VBN
cord-267965-84sotgds	214	20	multiple	multiple	JJ
cord-267965-84sotgds	214	21	loci	locus	NNS
cord-267965-84sotgds	214	22	associated	associate	VBN
cord-267965-84sotgds	214	23	with	with	IN
cord-267965-84sotgds	214	24	susceptibility	susceptibility	NN
cord-267965-84sotgds	214	25	(	(	-LRB-
cord-267965-84sotgds	214	26	Roy	Roy	NNP
cord-267965-84sotgds	214	27	Significance	significance	NN
cord-267965-84sotgds	214	28	threshold	threshold	NN
cord-267965-84sotgds	214	29	levels	level	NNS
cord-267965-84sotgds	214	30	:	:	:
cord-267965-84sotgds	214	31	*	*	NFP
cord-267965-84sotgds	214	32	<	<	XX
cord-267965-84sotgds	214	33	0.1	0.1	CD
cord-267965-84sotgds	214	34	,	,	,
cord-267965-84sotgds	215	1	*	*	NFP
cord-267965-84sotgds	215	2	*	*	NFP
cord-267965-84sotgds	215	3	0.1	0.1	CD
cord-267965-84sotgds	215	4	,	,	,
cord-267965-84sotgds	216	1	*	*	NFP
cord-267965-84sotgds	216	2	*	*	NFP
cord-267965-84sotgds	216	3	*	*	NFP
cord-267965-84sotgds	216	4	0.05	0.05	CD
cord-267965-84sotgds	216	5	.	.	.
cord-267965-84sotgds	217	1	Genome	genome	NN
cord-267965-84sotgds	217	2	coordinates	coordinate	VBZ
cord-267965-84sotgds	217	3	marked	mark	VBN
cord-267965-84sotgds	217	4	with	with	IN
cord-267965-84sotgds	217	5	0	0	CD
cord-267965-84sotgds	217	6	refer	refer	NN
cord-267965-84sotgds	217	7	to	to	IN
cord-267965-84sotgds	217	8	genome	genome	NN
cord-267965-84sotgds	217	9	assembly	assembly	NN
cord-267965-84sotgds	217	10	GSCv38	GSCv38	NNP
cord-267965-84sotgds	217	11	/	/	SYM
cord-267965-84sotgds	217	12	mm10	mm10	NNP
cord-267965-84sotgds	217	13	;	;	:
cord-267965-84sotgds	217	14	otherwise	otherwise	RB
cord-267965-84sotgds	217	15	,	,	,
cord-267965-84sotgds	217	16	coordinates	coordinate	VBZ
cord-267965-84sotgds	217	17	refer	refer	VBP
cord-267965-84sotgds	217	18	to	to	IN
cord-267965-84sotgds	217	19	MGSCv37	MGSCv37	NNP
cord-267965-84sotgds	217	20	/	/	SYM
cord-267965-84sotgds	217	21	mm9	mm9	NN
cord-267965-84sotgds	217	22	.	.	.
cord-267965-84sotgds	218	1	et	et	NNP
cord-267965-84sotgds	218	2	al	al	NNP
cord-267965-84sotgds	218	3	.	.	NNP
cord-267965-84sotgds	218	4	,	,	,
cord-267965-84sotgds	218	5	2006	2006	CD
cord-267965-84sotgds	218	6	;	;	:
cord-267965-84sotgds	218	7	Sebastiani	Sebastiani	NNP
cord-267965-84sotgds	218	8	et	et	NNP
cord-267965-84sotgds	218	9	al	al	NNP
cord-267965-84sotgds	218	10	.	.	NNP
cord-267965-84sotgds	218	11	,	,	,
cord-267965-84sotgds	218	12	1998	1998	CD
cord-267965-84sotgds	218	13	)	)	-RRB-
cord-267965-84sotgds	218	14	.	.	.
cord-267965-84sotgds	219	1	To	to	TO
cord-267965-84sotgds	219	2	identify	identify	VB
cord-267965-84sotgds	219	3	novel	novel	JJ
cord-267965-84sotgds	219	4	loci	locus	NNS
cord-267965-84sotgds	219	5	associated	associate	VBN
cord-267965-84sotgds	219	6	with	with	IN
cord-267965-84sotgds	219	7	S.	S.	NNP
cord-267965-84sotgds	219	8	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	219	9	susceptibility	susceptibility	NN
cord-267965-84sotgds	219	10	,	,	,
cord-267965-84sotgds	219	11	Zhang	Zhang	NNP
cord-267965-84sotgds	219	12	et	et	NNP
cord-267965-84sotgds	219	13	al	al	NNP
cord-267965-84sotgds	219	14	.	.	.
cord-267965-84sotgds	220	1	infected	infected	JJ
cord-267965-84sotgds	220	2	35	35	CD
cord-267965-84sotgds	220	3	CC	cc	NN
cord-267965-84sotgds	220	4	RI	RI	NNP
cord-267965-84sotgds	220	5	strains	strain	NNS
cord-267965-84sotgds	220	6	and	and	CC
cord-267965-84sotgds	220	7	measured	measure	VBN
cord-267965-84sotgds	220	8	bacterial	bacterial	JJ
cord-267965-84sotgds	220	9	load	load	NN
cord-267965-84sotgds	220	10	in	in	IN
cord-267965-84sotgds	220	11	the	the	DT
cord-267965-84sotgds	220	12	liver	liver	NN
cord-267965-84sotgds	220	13	and	and	CC
cord-267965-84sotgds	220	14	spleen	spleen	NNS
cord-267965-84sotgds	220	15	at	at	IN
cord-267965-84sotgds	220	16	4	4	CD
cord-267965-84sotgds	220	17	days	day	NNS
cord-267965-84sotgds	220	18	post	post	NN
cord-267965-84sotgds	220	19	-	-	NN
cord-267965-84sotgds	220	20	infection	infection	JJ
cord-267965-84sotgds	221	1	(	(	-LRB-
cord-267965-84sotgds	221	2	Zhang	Zhang	NNP
cord-267965-84sotgds	221	3	et	et	NNP
cord-267965-84sotgds	221	4	al	al	NNP
cord-267965-84sotgds	221	5	.	.	NNP
cord-267965-84sotgds	221	6	,	,	,
cord-267965-84sotgds	221	7	2018	2018	CD
cord-267965-84sotgds	221	8	)	)	-RRB-
cord-267965-84sotgds	221	9	.	.	.
cord-267965-84sotgds	222	1	QTL	QTL	NNP
cord-267965-84sotgds	222	2	scans	scan	VBZ
cord-267965-84sotgds	222	3	for	for	IN
cord-267965-84sotgds	222	4	bacterial	bacterial	JJ
cord-267965-84sotgds	222	5	load	load	NN
cord-267965-84sotgds	222	6	mapped	map	VBD
cord-267965-84sotgds	222	7	multiple	multiple	JJ
cord-267965-84sotgds	222	8	significant	significant	JJ
cord-267965-84sotgds	222	9	or	or	CC
cord-267965-84sotgds	222	10	suggestive	suggestive	JJ
cord-267965-84sotgds	222	11	QTL	qtl	NN
cord-267965-84sotgds	222	12	(	(	-LRB-
cord-267965-84sotgds	222	13	Figure	figure	NN
cord-267965-84sotgds	222	14	2	2	CD
cord-267965-84sotgds	222	15	;	;	:
cord-267965-84sotgds	222	16	Table	table	NN
cord-267965-84sotgds	222	17	1	1	CD
cord-267965-84sotgds	222	18	)	)	-RRB-
cord-267965-84sotgds	222	19	,	,	,
cord-267965-84sotgds	222	20	which	which	WDT
cord-267965-84sotgds	222	21	differed	differ	VBD
cord-267965-84sotgds	222	22	from	from	IN
cord-267965-84sotgds	222	23	those	those	DT
cord-267965-84sotgds	222	24	identified	identify	VBN
cord-267965-84sotgds	222	25	in	in	IN
cord-267965-84sotgds	222	26	studies	study	NNS
cord-267965-84sotgds	222	27	conducted	conduct	VBN
cord-267965-84sotgds	222	28	in	in	IN
cord-267965-84sotgds	222	29	other	other	JJ
cord-267965-84sotgds	222	30	mapping	mapping	NN
cord-267965-84sotgds	222	31	populations	population	NNS
cord-267965-84sotgds	222	32	(	(	-LRB-
cord-267965-84sotgds	222	33	Roy	Roy	NNP
cord-267965-84sotgds	222	34	et	et	NNP
cord-267965-84sotgds	222	35	al	al	NNP
cord-267965-84sotgds	222	36	.	.	NNP
cord-267965-84sotgds	222	37	,	,	,
cord-267965-84sotgds	222	38	2006	2006	CD
cord-267965-84sotgds	222	39	;	;	.
cord-267965-84sotgds	223	1	Sebastiani	Sebastiani	NNP
cord-267965-84sotgds	223	2	et	et	NNP
cord-267965-84sotgds	223	3	al	al	NNP
cord-267965-84sotgds	223	4	.	.	NNP
cord-267965-84sotgds	223	5	,	,	,
cord-267965-84sotgds	223	6	1998	1998	CD
cord-267965-84sotgds	223	7	)	)	-RRB-
cord-267965-84sotgds	223	8	.	.	.
cord-267965-84sotgds	224	1	Zhang	Zhang	NNP
cord-267965-84sotgds	224	2	et	et	NNP
cord-267965-84sotgds	224	3	al	al	NNP
cord-267965-84sotgds	224	4	.	.	.
cord-267965-84sotgds	225	1	used	use	VBN
cord-267965-84sotgds	225	2	merge	merge	VB
cord-267965-84sotgds	225	3	analysis	analysis	NN
cord-267965-84sotgds	225	4	in	in	IN
cord-267965-84sotgds	225	5	combination	combination	NN
cord-267965-84sotgds	225	6	with	with	IN
cord-267965-84sotgds	225	7	immune	immune	JJ
cord-267965-84sotgds	225	8	cell	cell	NN
cord-267965-84sotgds	225	9	gene	gene	NN
cord-267965-84sotgds	225	10	expression	expression	NN
cord-267965-84sotgds	225	11	,	,	,
cord-267965-84sotgds	225	12	gene	gene	NN
cord-267965-84sotgds	225	13	ontology	ontology	NN
cord-267965-84sotgds	225	14	,	,	,
cord-267965-84sotgds	225	15	and	and	CC
cord-267965-84sotgds	225	16	analysis	analysis	NN
cord-267965-84sotgds	225	17	of	of	IN
cord-267965-84sotgds	225	18	known	know	VBN
cord-267965-84sotgds	225	19	protein	protein	NN
cord-267965-84sotgds	225	20	functions	function	NNS
cord-267965-84sotgds	225	21	to	to	TO
cord-267965-84sotgds	225	22	narrow	narrow	VB
cord-267965-84sotgds	225	23	the	the	DT
cord-267965-84sotgds	225	24	list	list	NN
cord-267965-84sotgds	225	25	of	of	IN
cord-267965-84sotgds	225	26	candidate	candidate	NN
cord-267965-84sotgds	225	27	genes	gene	NNS
cord-267965-84sotgds	225	28	under	under	IN
cord-267965-84sotgds	225	29	the	the	DT
cord-267965-84sotgds	225	30	two	two	CD
cord-267965-84sotgds	225	31	significant	significant	JJ
cord-267965-84sotgds	225	32	loci	locus	NNS
cord-267965-84sotgds	225	33	.	.	.
cord-267965-84sotgds	226	1	They	-PRON-	PRP
cord-267965-84sotgds	226	2	identified	identify	VBD
cord-267965-84sotgds	226	3	candidate	candidate	NN
cord-267965-84sotgds	226	4	genes	gene	NNS
cord-267965-84sotgds	226	5	Cul4a	cul4a	NN
cord-267965-84sotgds	226	6	(	(	-LRB-
cord-267965-84sotgds	226	7	ubiquitin	ubiquitin	NNP
cord-267965-84sotgds	226	8	ligase	ligase	NN
cord-267965-84sotgds	226	9	)	)	-RRB-
cord-267965-84sotgds	226	10	,	,	.
cord-267965-84sotgds	227	1	Lamp1	lamp1	JJ
cord-267965-84sotgds	227	2	(	(	-LRB-
cord-267965-84sotgds	227	3	lysosomal	lysosomal	JJ
cord-267965-84sotgds	227	4	membrane	membrane	NN
cord-267965-84sotgds	227	5	protein	protein	NN
cord-267965-84sotgds	227	6	)	)	-RRB-
cord-267965-84sotgds	227	7	,	,	,
cord-267965-84sotgds	227	8	Mcf2l	Mcf2l	NNP
cord-267965-84sotgds	227	9	(	(	-LRB-
cord-267965-84sotgds	227	10	guanine	guanine	NNP
cord-267965-84sotgds	227	11	nucleotide	nucleotide	JJ
cord-267965-84sotgds	227	12	exchange	exchange	NN
cord-267965-84sotgds	227	13	factor	factor	NN
cord-267965-84sotgds	227	14	)	)	-RRB-
cord-267965-84sotgds	227	15	,	,	,
cord-267965-84sotgds	227	16	Pcid2	Pcid2	NNP
cord-267965-84sotgds	227	17	(	(	-LRB-
cord-267965-84sotgds	227	18	TREX-2	trex-2	JJ
cord-267965-84sotgds	227	19	complex	complex	JJ
cord-267965-84sotgds	227	20	component	component	NN
cord-267965-84sotgds	227	21	involved	involve	VBN
cord-267965-84sotgds	227	22	in	in	IN
cord-267965-84sotgds	227	23	mRNA	mRNA	NNP
cord-267965-84sotgds	227	24	nuclear	nuclear	JJ
cord-267965-84sotgds	227	25	export	export	NNP
cord-267965-84sotgds	227	26	)	)	-RRB-
cord-267965-84sotgds	227	27	,	,	,
cord-267965-84sotgds	227	28	and	and	CC
cord-267965-84sotgds	227	29	a	a	DT
cord-267965-84sotgds	227	30	high	high	JJ
cord-267965-84sotgds	227	31	-	-	HYPH
cord-267965-84sotgds	227	32	priority	priority	NN
cord-267965-84sotgds	227	33	candidate	candidate	NN
cord-267965-84sotgds	227	34	Slc35f1	slc35f1	NN
cord-267965-84sotgds	227	35	,	,	,
cord-267965-84sotgds	227	36	which	which	WDT
cord-267965-84sotgds	227	37	has	have	VBZ
cord-267965-84sotgds	227	38	lactate	lactate	NN
cord-267965-84sotgds	227	39	dehydrogenase	dehydrogenase	NN
cord-267965-84sotgds	227	40	activity	activity	NN
cord-267965-84sotgds	227	41	that	that	WDT
cord-267965-84sotgds	227	42	may	may	MD
cord-267965-84sotgds	227	43	be	be	VB
cord-267965-84sotgds	227	44	important	important	JJ
cord-267965-84sotgds	227	45	in	in	IN
cord-267965-84sotgds	227	46	the	the	DT
cord-267965-84sotgds	227	47	S.	S.	NNP
cord-267965-84sotgds	227	48	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	227	49	pyruvate	pyruvate	NN
cord-267965-84sotgds	227	50	metabolism	metabolism	NN
cord-267965-84sotgds	227	51	pathway	pathway	NN
cord-267965-84sotgds	227	52	.	.	.
cord-267965-84sotgds	228	1	The	the	DT
cord-267965-84sotgds	228	2	study	study	NN
cord-267965-84sotgds	228	3	also	also	RB
cord-267965-84sotgds	228	4	noted	note	VBD
cord-267965-84sotgds	228	5	that	that	IN
cord-267965-84sotgds	228	6	one	one	CD
cord-267965-84sotgds	228	7	strain	strain	NN
cord-267965-84sotgds	228	8	,	,	,
cord-267965-84sotgds	228	9	CC042	CC042	NNP
cord-267965-84sotgds	228	10	/	/	SYM
cord-267965-84sotgds	228	11	GeniUnc	GeniUnc	NNP
cord-267965-84sotgds	228	12	,	,	,
cord-267965-84sotgds	228	13	had	have	VBD
cord-267965-84sotgds	228	14	extremely	extremely	RB
cord-267965-84sotgds	228	15	high	high	JJ
cord-267965-84sotgds	228	16	bacterial	bacterial	JJ
cord-267965-84sotgds	228	17	loads	load	NNS
cord-267965-84sotgds	228	18	,	,	,
cord-267965-84sotgds	228	19	suggesting	suggest	VBG
cord-267965-84sotgds	228	20	that	that	IN
cord-267965-84sotgds	228	21	it	-PRON-	PRP
cord-267965-84sotgds	228	22	may	may	MD
cord-267965-84sotgds	228	23	be	be	VB
cord-267965-84sotgds	228	24	uniquely	uniquely	RB
cord-267965-84sotgds	228	25	susceptible	susceptible	JJ
cord-267965-84sotgds	228	26	to	to	IN
cord-267965-84sotgds	228	27	S.	S.	NNP
cord-267965-84sotgds	228	28	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	228	29	.	.	.
cord-267965-84sotgds	229	1	SARS	SARS	NNP
cord-267965-84sotgds	229	2	-	-	HYPH
cord-267965-84sotgds	229	3	CoV	CoV	NNP
cord-267965-84sotgds	229	4	causes	cause	VBZ
cord-267965-84sotgds	229	5	severe	severe	JJ
cord-267965-84sotgds	229	6	acute	acute	JJ
cord-267965-84sotgds	229	7	respiratory	respiratory	JJ
cord-267965-84sotgds	229	8	syndrome	syndrome	NN
cord-267965-84sotgds	229	9	in	in	IN
cord-267965-84sotgds	229	10	humans	human	NNS
cord-267965-84sotgds	229	11	,	,	,
cord-267965-84sotgds	229	12	but	but	CC
cord-267965-84sotgds	229	13	the	the	DT
cord-267965-84sotgds	229	14	genes	gene	NNS
cord-267965-84sotgds	229	15	regulating	regulate	VBG
cord-267965-84sotgds	229	16	these	these	DT
cord-267965-84sotgds	229	17	processes	process	NNS
cord-267965-84sotgds	229	18	are	be	VBP
cord-267965-84sotgds	229	19	poorly	poorly	RB
cord-267965-84sotgds	229	20	understood	understand	VBN
cord-267965-84sotgds	229	21	.	.	.
cord-267965-84sotgds	230	1	Gralinski	Gralinski	NNP
cord-267965-84sotgds	230	2	et	et	FW
cord-267965-84sotgds	230	3	al	al	NNP
cord-267965-84sotgds	230	4	.	.	.
cord-267965-84sotgds	231	1	infected	infect	VBN
cord-267965-84sotgds	231	2	the	the	DT
cord-267965-84sotgds	231	3	CC	CC	NNP
cord-267965-84sotgds	231	4	founder	founder	NN
cord-267965-84sotgds	231	5	strains	strain	NNS
cord-267965-84sotgds	231	6	and	and	CC
cord-267965-84sotgds	231	7	147	147	CD
cord-267965-84sotgds	231	8	pre	pre	JJ
cord-267965-84sotgds	231	9	-	-	JJ
cord-267965-84sotgds	231	10	CC	cc	JJ
cord-267965-84sotgds	231	11	lines	line	NNS
cord-267965-84sotgds	231	12	with	with	IN
cord-267965-84sotgds	231	13	mouse	mouse	NN
cord-267965-84sotgds	231	14	-	-	HYPH
cord-267965-84sotgds	231	15	adapted	adapt	VBN
cord-267965-84sotgds	231	16	SARS	SARS	NNP
cord-267965-84sotgds	231	17	-	-	HYPH
cord-267965-84sotgds	231	18	CoV	CoV	NNP
cord-267965-84sotgds	231	19	and	and	CC
cord-267965-84sotgds	231	20	studied	study	VBD
cord-267965-84sotgds	231	21	disease	disease	NN
cord-267965-84sotgds	231	22	through	through	IN
cord-267965-84sotgds	231	23	day	day	NN
cord-267965-84sotgds	231	24	4	4	CD
cord-267965-84sotgds	231	25	post	post	NN
cord-267965-84sotgds	231	26	-	-	NN
cord-267965-84sotgds	231	27	infection	infection	JJ
cord-267965-84sotgds	232	1	(	(	-LRB-
cord-267965-84sotgds	232	2	Gralinski	Gralinski	NNP
cord-267965-84sotgds	232	3	et	et	FW
cord-267965-84sotgds	232	4	al	al	NNP
cord-267965-84sotgds	232	5	.	.	NNP
cord-267965-84sotgds	232	6	,	,	,
cord-267965-84sotgds	232	7	2015	2015	CD
cord-267965-84sotgds	232	8	)	)	-RRB-
cord-267965-84sotgds	232	9	.	.	.
cord-267965-84sotgds	233	1	Variation	variation	NN
cord-267965-84sotgds	233	2	in	in	IN
cord-267965-84sotgds	233	3	weight	weight	NN
cord-267965-84sotgds	233	4	loss	loss	NN
cord-267965-84sotgds	233	5	and	and	CC
cord-267965-84sotgds	233	6	viral	viral	JJ
cord-267965-84sotgds	233	7	titer	titer	NN
cord-267965-84sotgds	233	8	was	be	VBD
cord-267965-84sotgds	233	9	significant	significant	JJ
cord-267965-84sotgds	233	10	in	in	IN
cord-267965-84sotgds	233	11	the	the	DT
cord-267965-84sotgds	233	12	CC	CC	NNP
cord-267965-84sotgds	233	13	founders	founder	NNS
cord-267965-84sotgds	233	14	and	and	CC
cord-267965-84sotgds	233	15	even	even	RB
cord-267965-84sotgds	233	16	broader	broader	RBR
cord-267965-84sotgds	233	17	in	in	IN
cord-267965-84sotgds	233	18	the	the	DT
cord-267965-84sotgds	233	19	pre	pre	JJ
cord-267965-84sotgds	233	20	-	-	JJ
cord-267965-84sotgds	233	21	CC	cc	JJ
cord-267965-84sotgds	233	22	mice	mouse	NNS
cord-267965-84sotgds	233	23	.	.	.
cord-267965-84sotgds	234	1	Similar	similar	JJ
cord-267965-84sotgds	234	2	to	to	IN
cord-267965-84sotgds	234	3	IAV	IAV	NNP
cord-267965-84sotgds	234	4	,	,	,
cord-267965-84sotgds	234	5	phenotypic	phenotypic	JJ
cord-267965-84sotgds	234	6	dissociation	dissociation	NN
cord-267965-84sotgds	234	7	was	be	VBD
cord-267965-84sotgds	234	8	observed	observe	VBN
cord-267965-84sotgds	234	9	in	in	IN
cord-267965-84sotgds	234	10	some	some	DT
cord-267965-84sotgds	234	11	pre	pre	JJ
cord-267965-84sotgds	234	12	-	-	JJ
cord-267965-84sotgds	234	13	CC	cc	JJ
cord-267965-84sotgds	234	14	lines	line	NNS
cord-267965-84sotgds	234	15	,	,	,
cord-267965-84sotgds	234	16	with	with	IN
cord-267965-84sotgds	234	17	viral	viral	JJ
cord-267965-84sotgds	234	18	titer	titer	NN
cord-267965-84sotgds	234	19	not	not	RB
cord-267965-84sotgds	234	20	correlated	correlate	VBN
cord-267965-84sotgds	234	21	with	with	IN
cord-267965-84sotgds	234	22	weight	weight	NN
cord-267965-84sotgds	234	23	loss	loss	NN
cord-267965-84sotgds	234	24	.	.	.
cord-267965-84sotgds	235	1	QTL	qtl	NN
cord-267965-84sotgds	235	2	mapping	mapping	NN
cord-267965-84sotgds	235	3	identified	identify	VBD
cord-267965-84sotgds	235	4	a	a	DT
cord-267965-84sotgds	235	5	significant	significant	JJ
cord-267965-84sotgds	235	6	main	main	JJ
cord-267965-84sotgds	235	7	effect	effect	NN
cord-267965-84sotgds	235	8	QTL	QTL	NNP
cord-267965-84sotgds	235	9	,	,	,
cord-267965-84sotgds	235	10	as	as	RB
cord-267965-84sotgds	235	11	well	well	RB
cord-267965-84sotgds	235	12	as	as	IN
cord-267965-84sotgds	235	13	a	a	DT
cord-267965-84sotgds	235	14	modifier	modifier	NN
cord-267965-84sotgds	235	15	QTL	QTL	NNP
cord-267965-84sotgds	235	16	for	for	IN
cord-267965-84sotgds	235	17	vascular	vascular	JJ
cord-267965-84sotgds	235	18	cuffing	cuffing	NN
cord-267965-84sotgds	235	19	in	in	IN
cord-267965-84sotgds	235	20	the	the	DT
cord-267965-84sotgds	235	21	lungs	lung	NNS
cord-267965-84sotgds	235	22	,	,	,
cord-267965-84sotgds	235	23	explaining	explain	VBG
cord-267965-84sotgds	235	24	26	26	CD
cord-267965-84sotgds	235	25	%	%	NN
cord-267965-84sotgds	235	26	and	and	CC
cord-267965-84sotgds	235	27	21	21	CD
cord-267965-84sotgds	235	28	%	%	NN
cord-267965-84sotgds	235	29	of	of	IN
cord-267965-84sotgds	235	30	the	the	DT
cord-267965-84sotgds	235	31	variation	variation	NN
cord-267965-84sotgds	235	32	,	,	,
cord-267965-84sotgds	235	33	respectively	respectively	RB
cord-267965-84sotgds	235	34	.	.	.
cord-267965-84sotgds	236	1	Suggestive	suggestive	JJ
cord-267965-84sotgds	236	2	QTLs	qtl	NNS
cord-267965-84sotgds	236	3	were	be	VBD
cord-267965-84sotgds	236	4	identified	identify	VBN
cord-267965-84sotgds	236	5	for	for	IN
cord-267965-84sotgds	236	6	eosinophilia	eosinophilia	NN
cord-267965-84sotgds	236	7	(	(	-LRB-
cord-267965-84sotgds	236	8	26	26	CD
cord-267965-84sotgds	236	9	%	%	NN
cord-267965-84sotgds	236	10	of	of	IN
cord-267965-84sotgds	236	11	variation	variation	NN
cord-267965-84sotgds	236	12	)	)	-RRB-
cord-267965-84sotgds	236	13	and	and	CC
cord-267965-84sotgds	236	14	viral	viral	JJ
cord-267965-84sotgds	236	15	titer	titer	NN
cord-267965-84sotgds	236	16	(	(	-LRB-
cord-267965-84sotgds	236	17	22	22	CD
cord-267965-84sotgds	236	18	%	%	NN
cord-267965-84sotgds	236	19	of	of	IN
cord-267965-84sotgds	236	20	variation	variation	NN
cord-267965-84sotgds	236	21	)	)	-RRB-
cord-267965-84sotgds	237	1	(	(	-LRB-
cord-267965-84sotgds	237	2	Figure	figure	NN
cord-267965-84sotgds	237	3	2	2	CD
cord-267965-84sotgds	237	4	;	;	:
cord-267965-84sotgds	237	5	Table	table	NN
cord-267965-84sotgds	237	6	1	1	CD
cord-267965-84sotgds	237	7	)	)	-RRB-
cord-267965-84sotgds	237	8	.	.	.
cord-267965-84sotgds	238	1	The	the	DT
cord-267965-84sotgds	238	2	candidate	candidate	NN
cord-267965-84sotgds	238	3	region	region	NN
cord-267965-84sotgds	238	4	for	for	IN
cord-267965-84sotgds	238	5	the	the	DT
cord-267965-84sotgds	238	6	main	main	JJ
cord-267965-84sotgds	238	7	effect	effect	NN
cord-267965-84sotgds	238	8	vascular	vascular	JJ
cord-267965-84sotgds	238	9	cuffing	cuffing	NN
cord-267965-84sotgds	238	10	QTL	QTL	NNP
cord-267965-84sotgds	238	11	was	be	VBD
cord-267965-84sotgds	238	12	narrowed	narrow	VBN
cord-267965-84sotgds	238	13	to	to	IN
cord-267965-84sotgds	238	14	a	a	DT
cord-267965-84sotgds	238	15	small	small	JJ
cord-267965-84sotgds	238	16	450	450	CD
cord-267965-84sotgds	238	17	kb	kb	NNP
cord-267965-84sotgds	238	18	region	region	NN
cord-267965-84sotgds	238	19	of	of	IN
cord-267965-84sotgds	238	20	shared	share	VBN
cord-267965-84sotgds	238	21	ancestry	ancestry	NN
cord-267965-84sotgds	238	22	between	between	IN
cord-267965-84sotgds	238	23	the	the	DT
cord-267965-84sotgds	238	24	high	high	JJ
cord-267965-84sotgds	238	25	-	-	HYPH
cord-267965-84sotgds	238	26	response	response	NN
cord-267965-84sotgds	238	27	haplotypes	haplotype	NNS
cord-267965-84sotgds	238	28	.	.	.
cord-267965-84sotgds	239	1	This	this	DT
cord-267965-84sotgds	239	2	region	region	NN
cord-267965-84sotgds	239	3	contained	contain	VBD
cord-267965-84sotgds	239	4	only	only	RB
cord-267965-84sotgds	239	5	one	one	CD
cord-267965-84sotgds	239	6	functional	functional	JJ
cord-267965-84sotgds	239	7	gene	gene	NN
cord-267965-84sotgds	239	8	,	,	,
cord-267965-84sotgds	239	9	Trim55	trim55	CD
cord-267965-84sotgds	239	10	,	,	,
cord-267965-84sotgds	239	11	a	a	DT
cord-267965-84sotgds	239	12	RING	ring	NN
cord-267965-84sotgds	239	13	zinc	zinc	NN
cord-267965-84sotgds	239	14	-	-	HYPH
cord-267965-84sotgds	239	15	finger	finger	NN
cord-267965-84sotgds	239	16	-	-	HYPH
cord-267965-84sotgds	239	17	containing	contain	VBG
cord-267965-84sotgds	239	18	protein	protein	NN
cord-267965-84sotgds	239	19	expressed	express	VBN
cord-267965-84sotgds	239	20	in	in	IN
cord-267965-84sotgds	239	21	smooth	smooth	JJ
cord-267965-84sotgds	239	22	muscle	muscle	NN
cord-267965-84sotgds	239	23	,	,	,
cord-267965-84sotgds	239	24	which	which	WDT
cord-267965-84sotgds	239	25	had	have	VBD
cord-267965-84sotgds	239	26	not	not	RB
cord-267965-84sotgds	239	27	previously	previously	RB
cord-267965-84sotgds	239	28	been	be	VBN
cord-267965-84sotgds	239	29	implicated	implicate	VBN
cord-267965-84sotgds	239	30	in	in	IN
cord-267965-84sotgds	239	31	any	any	DT
cord-267965-84sotgds	239	32	immune	immune	JJ
cord-267965-84sotgds	239	33	phenotypes	phenotype	NNS
cord-267965-84sotgds	239	34	.	.	.
cord-267965-84sotgds	240	1	Follow	follow	VB
cord-267965-84sotgds	240	2	-	-	HYPH
cord-267965-84sotgds	240	3	up	up	RP
cord-267965-84sotgds	240	4	validation	validation	NN
cord-267965-84sotgds	240	5	studies	study	NNS
cord-267965-84sotgds	240	6	using	use	VBG
cord-267965-84sotgds	240	7	Trim55	trim55	CD
cord-267965-84sotgds	240	8	knockout	knockout	NN
cord-267965-84sotgds	240	9	mice	mouse	NNS
cord-267965-84sotgds	240	10	,	,	,
cord-267965-84sotgds	240	11	which	which	WDT
cord-267965-84sotgds	240	12	showed	show	VBD
cord-267965-84sotgds	240	13	altered	altered	JJ
cord-267965-84sotgds	240	14	chemokine	chemokine	NN
cord-267965-84sotgds	240	15	and	and	CC
cord-267965-84sotgds	240	16	tight	tight	JJ
cord-267965-84sotgds	240	17	junction	junction	NN
cord-267965-84sotgds	240	18	gene	gene	NN
cord-267965-84sotgds	240	19	expression	expression	NN
cord-267965-84sotgds	240	20	as	as	RB
cord-267965-84sotgds	240	21	well	well	RB
cord-267965-84sotgds	240	22	as	as	IN
cord-267965-84sotgds	240	23	altered	alter	VBN
cord-267965-84sotgds	240	24	inflammatory	inflammatory	JJ
cord-267965-84sotgds	240	25	cell	cell	NN
cord-267965-84sotgds	240	26	recruitment	recruitment	NN
cord-267965-84sotgds	240	27	,	,	,
cord-267965-84sotgds	240	28	confirmed	confirm	VBD
cord-267965-84sotgds	240	29	a	a	DT
cord-267965-84sotgds	240	30	role	role	NN
cord-267965-84sotgds	240	31	for	for	IN
cord-267965-84sotgds	240	32	this	this	DT
cord-267965-84sotgds	240	33	gene	gene	NN
cord-267965-84sotgds	240	34	in	in	IN
cord-267965-84sotgds	240	35	SARS	SARS	NNP
cord-267965-84sotgds	240	36	-	-	HYPH
cord-267965-84sotgds	240	37	CoVinduced	CoVinduced	NNP
cord-267965-84sotgds	240	38	vascular	vascular	JJ
cord-267965-84sotgds	240	39	cuffing	cuffing	NN
cord-267965-84sotgds	240	40	.	.	.
cord-267965-84sotgds	241	1	The	the	DT
cord-267965-84sotgds	241	2	authors	author	NNS
cord-267965-84sotgds	241	3	also	also	RB
cord-267965-84sotgds	241	4	noted	note	VBD
cord-267965-84sotgds	241	5	a	a	DT
cord-267965-84sotgds	241	6	high	high	JJ
cord-267965-84sotgds	241	7	-	-	HYPH
cord-267965-84sotgds	241	8	priority	priority	NN
cord-267965-84sotgds	241	9	candidate	candidate	NN
cord-267965-84sotgds	241	10	under	under	IN
cord-267965-84sotgds	241	11	the	the	DT
cord-267965-84sotgds	241	12	modifier	modifier	NN
cord-267965-84sotgds	241	13	QTL	QTL	NNP
cord-267965-84sotgds	241	14	,	,	,
cord-267965-84sotgds	241	15	the	the	DT
cord-267965-84sotgds	241	16	cadherin	cadherin	NN
cord-267965-84sotgds	241	17	family	family	NN
cord-267965-84sotgds	241	18	member	member	NN
cord-267965-84sotgds	241	19	Cdhr2	Cdhr2	NNP
cord-267965-84sotgds	241	20	,	,	,
cord-267965-84sotgds	241	21	which	which	WDT
cord-267965-84sotgds	241	22	may	may	MD
cord-267965-84sotgds	241	23	be	be	VB
cord-267965-84sotgds	241	24	involved	involve	VBN
cord-267965-84sotgds	241	25	in	in	IN
cord-267965-84sotgds	241	26	migration	migration	NN
cord-267965-84sotgds	241	27	of	of	IN
cord-267965-84sotgds	241	28	inflammatory	inflammatory	JJ
cord-267965-84sotgds	241	29	cell	cell	NN
cord-267965-84sotgds	241	30	from	from	IN
cord-267965-84sotgds	241	31	the	the	DT
cord-267965-84sotgds	241	32	blood	blood	NN
cord-267965-84sotgds	241	33	into	into	IN
cord-267965-84sotgds	241	34	the	the	DT
cord-267965-84sotgds	241	35	lung	lung	NN
cord-267965-84sotgds	241	36	.	.	.
cord-267965-84sotgds	242	1	In	in	IN
cord-267965-84sotgds	242	2	a	a	DT
cord-267965-84sotgds	242	3	subsequent	subsequent	JJ
cord-267965-84sotgds	242	4	study	study	NN
cord-267965-84sotgds	242	5	,	,	,
cord-267965-84sotgds	242	6	Gralinksi	Gralinksi	NNP
cord-267965-84sotgds	242	7	et	et	NNP
cord-267965-84sotgds	242	8	al	al	NNP
cord-267965-84sotgds	242	9	.	.	NNP
cord-267965-84sotgds	242	10	used	use	VBD
cord-267965-84sotgds	242	11	an	an	DT
cord-267965-84sotgds	242	12	F2	f2	NN
cord-267965-84sotgds	242	13	cross	cross	NN
cord-267965-84sotgds	242	14	between	between	IN
cord-267965-84sotgds	242	15	two	two	CD
cord-267965-84sotgds	242	16	CC	CC	NNP
cord-267965-84sotgds	242	17	-	-	HYPH
cord-267965-84sotgds	242	18	RI	RI	NNP
cord-267965-84sotgds	242	19	strains	strain	NNS
cord-267965-84sotgds	242	20	with	with	IN
cord-267965-84sotgds	242	21	highly	highly	RB
cord-267965-84sotgds	242	22	divergent	divergent	JJ
cord-267965-84sotgds	242	23	SARS	SARS	NNP
cord-267965-84sotgds	242	24	-	-	HYPH
cord-267965-84sotgds	242	25	CoV	cov	NN
cord-267965-84sotgds	242	26	susceptibilities	susceptibility	NNS
cord-267965-84sotgds	242	27	to	to	TO
cord-267965-84sotgds	242	28	map	map	VB
cord-267965-84sotgds	242	29	five	five	CD
cord-267965-84sotgds	242	30	significant	significant	JJ
cord-267965-84sotgds	242	31	loci	locus	NNS
cord-267965-84sotgds	242	32	affecting	affect	VBG
cord-267965-84sotgds	242	33	weight	weight	NN
cord-267965-84sotgds	242	34	loss	loss	NN
cord-267965-84sotgds	242	35	,	,	,
cord-267965-84sotgds	242	36	viral	viral	JJ
cord-267965-84sotgds	242	37	titer	titer	NN
cord-267965-84sotgds	242	38	,	,	,
cord-267965-84sotgds	242	39	and	and	CC
cord-267965-84sotgds	242	40	other	other	JJ
cord-267965-84sotgds	242	41	disease	disease	NN
cord-267965-84sotgds	242	42	phenotypes	phenotype	NNS
cord-267965-84sotgds	242	43	,	,	,
cord-267965-84sotgds	242	44	including	include	VBG
cord-267965-84sotgds	242	45	one	one	CD
cord-267965-84sotgds	242	46	main	main	JJ
cord-267965-84sotgds	242	47	effect	effect	NN
cord-267965-84sotgds	242	48	QTL	QTL	NNP
cord-267965-84sotgds	242	49	that	that	WDT
cord-267965-84sotgds	242	50	explained	explain	VBD
cord-267965-84sotgds	242	51	between	between	IN
cord-267965-84sotgds	242	52	6	6	CD
cord-267965-84sotgds	242	53	%	%	NN
cord-267965-84sotgds	242	54	and	and	CC
cord-267965-84sotgds	242	55	12	12	CD
cord-267965-84sotgds	242	56	%	%	NN
cord-267965-84sotgds	242	57	of	of	IN
cord-267965-84sotgds	242	58	the	the	DT
cord-267965-84sotgds	242	59	variation	variation	NN
cord-267965-84sotgds	242	60	in	in	IN
cord-267965-84sotgds	242	61	every	every	DT
cord-267965-84sotgds	242	62	phenotype	phenotype	NN
cord-267965-84sotgds	242	63	(	(	-LRB-
cord-267965-84sotgds	242	64	Gralinski	Gralinski	NNP
cord-267965-84sotgds	242	65	et	et	FW
cord-267965-84sotgds	242	66	al	al	NNP
cord-267965-84sotgds	242	67	.	.	NNP
cord-267965-84sotgds	242	68	,	,	,
cord-267965-84sotgds	242	69	2017	2017	CD
cord-267965-84sotgds	242	70	)	)	-RRB-
cord-267965-84sotgds	242	71	.	.	.
cord-267965-84sotgds	243	1	Ticam2	Ticam2	NNP
cord-267965-84sotgds	243	2	,	,	,
cord-267965-84sotgds	243	3	a	a	DT
cord-267965-84sotgds	243	4	TLR4	TLR4	NNP
cord-267965-84sotgds	243	5	adaptor	adaptor	NN
cord-267965-84sotgds	243	6	protein	protein	NN
cord-267965-84sotgds	243	7	,	,	,
cord-267965-84sotgds	243	8	was	be	VBD
cord-267965-84sotgds	243	9	identified	identify	VBN
cord-267965-84sotgds	243	10	as	as	IN
cord-267965-84sotgds	243	11	a	a	DT
cord-267965-84sotgds	243	12	high	high	JJ
cord-267965-84sotgds	243	13	-	-	HYPH
cord-267965-84sotgds	243	14	priority	priority	NN
cord-267965-84sotgds	243	15	candidate	candidate	NN
cord-267965-84sotgds	243	16	gene	gene	NN
cord-267965-84sotgds	243	17	under	under	IN
cord-267965-84sotgds	243	18	the	the	DT
cord-267965-84sotgds	243	19	main	main	JJ
cord-267965-84sotgds	243	20	effect	effect	NN
cord-267965-84sotgds	243	21	QTL	QTL	NNP
cord-267965-84sotgds	243	22	given	give	VBD
cord-267965-84sotgds	243	23	the	the	DT
cord-267965-84sotgds	243	24	known	know	VBN
cord-267965-84sotgds	243	25	importance	importance	NN
cord-267965-84sotgds	243	26	of	of	IN
cord-267965-84sotgds	243	27	TLR4	TLR4	NNP
cord-267965-84sotgds	243	28	in	in	IN
cord-267965-84sotgds	243	29	SARS	SARS	NNP
cord-267965-84sotgds	243	30	-	-	HYPH
cord-267965-84sotgds	243	31	CoV	CoV	NNP
cord-267965-84sotgds	243	32	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	244	1	(	(	-LRB-
cord-267965-84sotgds	244	2	Totura	Totura	NNP
cord-267965-84sotgds	244	3	et	et	FW
cord-267965-84sotgds	244	4	al	al	NNP
cord-267965-84sotgds	244	5	.	.	NNP
cord-267965-84sotgds	244	6	,	,	,
cord-267965-84sotgds	244	7	2015	2015	CD
cord-267965-84sotgds	244	8	)	)	-RRB-
cord-267965-84sotgds	244	9	.	.	.
cord-267965-84sotgds	245	1	Ticam2	ticam2	CD
cord-267965-84sotgds	245	2	knockout	knockout	NN
cord-267965-84sotgds	245	3	mice	mouse	NNS
cord-267965-84sotgds	245	4	had	have	VBD
cord-267965-84sotgds	245	5	increased	increase	VBN
cord-267965-84sotgds	245	6	SARS	SARS	NNP
cord-267965-84sotgds	245	7	-	-	HYPH
cord-267965-84sotgds	245	8	CoV	CoV	NNP
cord-267965-84sotgds	245	9	-	-	HYPH
cord-267965-84sotgds	245	10	induced	induce	VBN
cord-267965-84sotgds	245	11	weight	weight	NN
cord-267965-84sotgds	245	12	loss	loss	NN
cord-267965-84sotgds	245	13	,	,	,
cord-267965-84sotgds	245	14	early	early	JJ
cord-267965-84sotgds	245	15	viral	viral	JJ
cord-267965-84sotgds	245	16	titers	titer	NNS
cord-267965-84sotgds	245	17	,	,	,
cord-267965-84sotgds	245	18	and	and	CC
cord-267965-84sotgds	245	19	pulmonary	pulmonary	JJ
cord-267965-84sotgds	245	20	hemorrhage	hemorrhage	NN
cord-267965-84sotgds	245	21	.	.	.
cord-267965-84sotgds	246	1	In	in	IN
cord-267965-84sotgds	246	2	addition	addition	NN
cord-267965-84sotgds	246	3	to	to	IN
cord-267965-84sotgds	246	4	exhibiting	exhibit	VBG
cord-267965-84sotgds	246	5	high	high	JJ
cord-267965-84sotgds	246	6	levels	level	NNS
cord-267965-84sotgds	246	7	of	of	IN
cord-267965-84sotgds	246	8	variation	variation	NN
cord-267965-84sotgds	246	9	in	in	IN
cord-267965-84sotgds	246	10	pathogeninduced	pathogeninduce	VBN
cord-267965-84sotgds	246	11	responses	response	NNS
cord-267965-84sotgds	246	12	,	,	,
cord-267965-84sotgds	246	13	the	the	DT
cord-267965-84sotgds	246	14	CC	CC	NNP
cord-267965-84sotgds	246	15	also	also	RB
cord-267965-84sotgds	246	16	exhibits	exhibit	VBZ
cord-267965-84sotgds	246	17	variation	variation	NN
cord-267965-84sotgds	246	18	in	in	IN
cord-267965-84sotgds	246	19	baseline	baseline	JJ
cord-267965-84sotgds	246	20	(	(	-LRB-
cord-267965-84sotgds	246	21	homeostatic	homeostatic	JJ
cord-267965-84sotgds	246	22	)	)	-RRB-
cord-267965-84sotgds	246	23	immunity	immunity	NN
cord-267965-84sotgds	246	24	.	.	.
cord-267965-84sotgds	247	1	Variation	variation	NN
cord-267965-84sotgds	247	2	in	in	IN
cord-267965-84sotgds	247	3	immune	immune	JJ
cord-267965-84sotgds	247	4	homeostasis	homeostasis	NN
cord-267965-84sotgds	247	5	has	have	VBZ
cord-267965-84sotgds	247	6	been	be	VBN
cord-267965-84sotgds	247	7	associated	associate	VBN
cord-267965-84sotgds	247	8	with	with	IN
cord-267965-84sotgds	247	9	variation	variation	NN
cord-267965-84sotgds	247	10	in	in	IN
cord-267965-84sotgds	247	11	vaccine	vaccine	NN
cord-267965-84sotgds	247	12	responses	response	NNS
cord-267965-84sotgds	247	13	in	in	IN
cord-267965-84sotgds	247	14	humans	human	NNS
cord-267965-84sotgds	247	15	(	(	-LRB-
cord-267965-84sotgds	247	16	Tsang	Tsang	NNP
cord-267965-84sotgds	247	17	et	et	NNP
cord-267965-84sotgds	247	18	al	al	NNP
cord-267965-84sotgds	247	19	.	.	.
cord-267965-84sotgds	248	1	,	,	,
cord-267965-84sotgds	248	2	2014	2014	CD
cord-267965-84sotgds	248	3	)	)	-RRB-
cord-267965-84sotgds	248	4	,	,	,
cord-267965-84sotgds	248	5	and	and	CC
cord-267965-84sotgds	248	6	the	the	DT
cord-267965-84sotgds	248	7	CC	CC	NNP
cord-267965-84sotgds	248	8	provides	provide	VBZ
cord-267965-84sotgds	248	9	a	a	DT
cord-267965-84sotgds	248	10	novel	novel	JJ
cord-267965-84sotgds	248	11	resource	resource	NN
cord-267965-84sotgds	248	12	to	to	TO
cord-267965-84sotgds	248	13	study	study	VB
cord-267965-84sotgds	248	14	how	how	WRB
cord-267965-84sotgds	248	15	variation	variation	NN
cord-267965-84sotgds	248	16	in	in	IN
cord-267965-84sotgds	248	17	pre	pre	JJ
cord-267965-84sotgds	248	18	-	-	JJ
cord-267965-84sotgds	248	19	existing	existing	JJ
cord-267965-84sotgds	248	20	immunity	immunity	NN
cord-267965-84sotgds	248	21	affects	affect	VBZ
cord-267965-84sotgds	248	22	the	the	DT
cord-267965-84sotgds	248	23	host	host	NN
cord-267965-84sotgds	248	24	response	response	NN
cord-267965-84sotgds	248	25	to	to	IN
cord-267965-84sotgds	248	26	infection	infection	NN
cord-267965-84sotgds	248	27	or	or	CC
cord-267965-84sotgds	248	28	vaccination	vaccination	NN
cord-267965-84sotgds	248	29	.	.	.
cord-267965-84sotgds	249	1	Phillippi	Phillippi	NNP
cord-267965-84sotgds	249	2	et	et	NNP
cord-267965-84sotgds	249	3	al	al	NNP
cord-267965-84sotgds	249	4	.	.	.
cord-267965-84sotgds	249	5	analyzed	analyze	VBD
cord-267965-84sotgds	249	6	subsets	subset	NNS
cord-267965-84sotgds	249	7	of	of	IN
cord-267965-84sotgds	249	8	lymphocytes	lymphocyte	NNS
cord-267965-84sotgds	249	9	and	and	CC
cord-267965-84sotgds	249	10	antigen	antigen	NN
cord-267965-84sotgds	249	11	-	-	HYPH
cord-267965-84sotgds	249	12	presenting	present	VBG
cord-267965-84sotgds	249	13	cells	cell	NNS
cord-267965-84sotgds	249	14	in	in	IN
cord-267965-84sotgds	249	15	the	the	DT
cord-267965-84sotgds	249	16	CC	CC	NNP
cord-267965-84sotgds	249	17	founders	founder	NNS
cord-267965-84sotgds	249	18	,	,	,
cord-267965-84sotgds	249	19	CC	CC	NNP
cord-267965-84sotgds	249	20	founder	founder	NN
cord-267965-84sotgds	249	21	F1s	F1s	NNP
cord-267965-84sotgds	249	22	,	,	,
cord-267965-84sotgds	249	23	and	and	CC
cord-267965-84sotgds	249	24	66	66	CD
cord-267965-84sotgds	249	25	pre	pre	JJ
cord-267965-84sotgds	249	26	-	-	JJ
cord-267965-84sotgds	249	27	CC	cc	JJ
cord-267965-84sotgds	249	28	strains	strain	NNS
cord-267965-84sotgds	249	29	(	(	-LRB-
cord-267965-84sotgds	249	30	Phillippi	Phillippi	NNP
cord-267965-84sotgds	249	31	et	et	NNP
cord-267965-84sotgds	249	32	al	al	NNP
cord-267965-84sotgds	249	33	.	.	NNP
cord-267965-84sotgds	249	34	,	,	,
cord-267965-84sotgds	249	35	2014	2014	CD
cord-267965-84sotgds	249	36	)	)	-RRB-
cord-267965-84sotgds	249	37	.	.	.
cord-267965-84sotgds	250	1	They	-PRON-	PRP
cord-267965-84sotgds	250	2	observed	observe	VBD
cord-267965-84sotgds	250	3	variation	variation	NN
cord-267965-84sotgds	250	4	in	in	IN
cord-267965-84sotgds	250	5	the	the	DT
cord-267965-84sotgds	250	6	pre	pre	JJ
cord-267965-84sotgds	250	7	-	-	NN
cord-267965-84sotgds	250	8	CC	cc	NN
cord-267965-84sotgds	250	9	exceeding	exceed	VBG
cord-267965-84sotgds	250	10	that	that	IN
cord-267965-84sotgds	250	11	in	in	IN
cord-267965-84sotgds	250	12	the	the	DT
cord-267965-84sotgds	250	13	founders	founder	NNS
cord-267965-84sotgds	250	14	,	,	,
cord-267965-84sotgds	250	15	as	as	RB
cord-267965-84sotgds	250	16	well	well	RB
cord-267965-84sotgds	250	17	as	as	IN
cord-267965-84sotgds	250	18	novel	novel	JJ
cord-267965-84sotgds	250	19	extreme	extreme	JJ
cord-267965-84sotgds	250	20	phenotypes	phenotype	NNS
cord-267965-84sotgds	250	21	such	such	JJ
cord-267965-84sotgds	250	22	as	as	IN
cord-267965-84sotgds	250	23	lymphopenia	lymphopenia	NNP
cord-267965-84sotgds	250	24	and	and	CC
cord-267965-84sotgds	250	25	inverted	invert	VBN
cord-267965-84sotgds	250	26	CD4	CD4	NNP
cord-267965-84sotgds	250	27	/	/	SYM
cord-267965-84sotgds	250	28	CD8	CD8	NNP
cord-267965-84sotgds	250	29	ratios	ratio	NNS
cord-267965-84sotgds	250	30	.	.	.
cord-267965-84sotgds	251	1	While	while	IN
cord-267965-84sotgds	251	2	some	some	DT
cord-267965-84sotgds	251	3	immune	immune	JJ
cord-267965-84sotgds	251	4	phenotypes	phenotype	NNS
cord-267965-84sotgds	251	5	were	be	VBD
cord-267965-84sotgds	251	6	highly	highly	RB
cord-267965-84sotgds	251	7	correlated	correlate	VBN
cord-267965-84sotgds	251	8	,	,	,
cord-267965-84sotgds	251	9	others	other	NNS
cord-267965-84sotgds	251	10	showed	show	VBD
cord-267965-84sotgds	251	11	little	little	JJ
cord-267965-84sotgds	251	12	or	or	CC
cord-267965-84sotgds	251	13	no	no	DT
cord-267965-84sotgds	251	14	correlation	correlation	NN
cord-267965-84sotgds	251	15	to	to	IN
cord-267965-84sotgds	251	16	other	other	JJ
cord-267965-84sotgds	251	17	immune	immune	JJ
cord-267965-84sotgds	251	18	populations	population	NNS
cord-267965-84sotgds	251	19	.	.	.
cord-267965-84sotgds	252	1	Mapping	mapping	NN
cord-267965-84sotgds	252	2	identified	identify	VBD
cord-267965-84sotgds	252	3	10	10	CD
cord-267965-84sotgds	252	4	significant	significant	JJ
cord-267965-84sotgds	252	5	QTLs	qtl	NNS
cord-267965-84sotgds	252	6	across	across	IN
cord-267965-84sotgds	252	7	8	8	CD
cord-267965-84sotgds	252	8	phenotypes	phenotype	NNS
cord-267965-84sotgds	252	9	,	,	,
cord-267965-84sotgds	252	10	including	include	VBG
cord-267965-84sotgds	252	11	B	b	NN
cord-267965-84sotgds	252	12	/	/	SYM
cord-267965-84sotgds	252	13	T	t	NN
cord-267965-84sotgds	252	14	cell	cell	NN
cord-267965-84sotgds	252	15	ratio	ratio	NN
cord-267965-84sotgds	252	16	and	and	CC
cord-267965-84sotgds	252	17	mean	mean	VB
cord-267965-84sotgds	252	18	fluorescence	fluorescence	NN
cord-267965-84sotgds	252	19	intensity	intensity	NN
cord-267965-84sotgds	252	20	for	for	IN
cord-267965-84sotgds	252	21	CD23	CD23	NNP
cord-267965-84sotgds	252	22	,	,	,
cord-267965-84sotgds	252	23	also	also	RB
cord-267965-84sotgds	252	24	known	know	VBN
cord-267965-84sotgds	252	25	as	as	IN
cord-267965-84sotgds	252	26	Fc	Fc	NNP
cord-267965-84sotgds	252	27	epsilon	epsilon	NN
cord-267965-84sotgds	252	28	RII	RII	NNP
cord-267965-84sotgds	252	29	.	.	.
cord-267965-84sotgds	253	1	The	the	DT
cord-267965-84sotgds	253	2	CD23	CD23	NNP
cord-267965-84sotgds	253	3	QTL	QTL	NNP
cord-267965-84sotgds	253	4	contains	contain	VBZ
cord-267965-84sotgds	253	5	the	the	DT
cord-267965-84sotgds	253	6	gene	gene	NN
cord-267965-84sotgds	253	7	Fcer2a	Fcer2a	NNP
cord-267965-84sotgds	253	8	,	,	,
cord-267965-84sotgds	253	9	which	which	WDT
cord-267965-84sotgds	253	10	codes	code	VBZ
cord-267965-84sotgds	253	11	for	for	IN
cord-267965-84sotgds	253	12	CD23	CD23	NNP
cord-267965-84sotgds	253	13	itself	-PRON-	PRP
cord-267965-84sotgds	253	14	,	,	,
cord-267965-84sotgds	253	15	and	and	CC
cord-267965-84sotgds	253	16	a	a	DT
cord-267965-84sotgds	253	17	combination	combination	NN
cord-267965-84sotgds	253	18	of	of	IN
cord-267965-84sotgds	253	19	merge	merge	NN
cord-267965-84sotgds	253	20	analysis	analysis	NN
cord-267965-84sotgds	253	21	,	,	,
cord-267965-84sotgds	253	22	conditional	conditional	NNP
cord-267965-84sotgds	253	23	association	association	NNP
cord-267965-84sotgds	253	24	,	,	,
cord-267965-84sotgds	253	25	and	and	CC
cord-267965-84sotgds	253	26	residue	residue	NN
cord-267965-84sotgds	253	27	conservation	conservation	NN
cord-267965-84sotgds	253	28	was	be	VBD
cord-267965-84sotgds	253	29	used	use	VBN
cord-267965-84sotgds	253	30	to	to	TO
cord-267965-84sotgds	253	31	identify	identify	VB
cord-267965-84sotgds	253	32	specific	specific	JJ
cord-267965-84sotgds	253	33	coding	code	VBG
cord-267965-84sotgds	253	34	polymorphisms	polymorphism	NNS
cord-267965-84sotgds	253	35	within	within	IN
cord-267965-84sotgds	253	36	Fcer2a	fcer2a	NN
cord-267965-84sotgds	253	37	driving	drive	VBG
cord-267965-84sotgds	253	38	the	the	DT
cord-267965-84sotgds	253	39	QTL	QTL	NNP
cord-267965-84sotgds	253	40	.	.	.
cord-267965-84sotgds	254	1	Graham	Graham	NNP
cord-267965-84sotgds	254	2	et	et	NNP
cord-267965-84sotgds	254	3	al	al	NNP
cord-267965-84sotgds	254	4	.	.	.
cord-267965-84sotgds	255	1	also	also	RB
cord-267965-84sotgds	255	2	performed	perform	VBD
cord-267965-84sotgds	255	3	an	an	DT
cord-267965-84sotgds	255	4	extensive	extensive	JJ
cord-267965-84sotgds	255	5	examination	examination	NN
cord-267965-84sotgds	255	6	of	of	IN
cord-267965-84sotgds	255	7	homeostatic	homeostatic	JJ
cord-267965-84sotgds	255	8	immunity	immunity	NN
cord-267965-84sotgds	255	9	in	in	IN
cord-267965-84sotgds	255	10	over	over	IN
cord-267965-84sotgds	255	11	100	100	CD
cord-267965-84sotgds	255	12	CC	CC	NNP
cord-267965-84sotgds	255	13	-	-	HYPH
cord-267965-84sotgds	255	14	F1	F1	NNP
cord-267965-84sotgds	255	15	crosses	cross	VBZ
cord-267965-84sotgds	255	16	,	,	,
cord-267965-84sotgds	255	17	with	with	IN
cord-267965-84sotgds	255	18	a	a	DT
cord-267965-84sotgds	255	19	focus	focus	NN
cord-267965-84sotgds	255	20	on	on	IN
cord-267965-84sotgds	255	21	T	T	NNP
cord-267965-84sotgds	255	22	cell	cell	NN
cord-267965-84sotgds	255	23	populations	population	NNS
cord-267965-84sotgds	255	24	,	,	,
cord-267965-84sotgds	255	25	expression	expression	NN
cord-267965-84sotgds	255	26	of	of	IN
cord-267965-84sotgds	255	27	activation	activation	NN
cord-267965-84sotgds	255	28	markers	marker	NNS
cord-267965-84sotgds	255	29	,	,	,
cord-267965-84sotgds	255	30	and	and	CC
cord-267965-84sotgds	255	31	production	production	NN
cord-267965-84sotgds	255	32	of	of	IN
cord-267965-84sotgds	255	33	inflammatory	inflammatory	JJ
cord-267965-84sotgds	255	34	cytokines	cytokine	NNS
cord-267965-84sotgds	255	35	(	(	-LRB-
cord-267965-84sotgds	255	36	Graham	Graham	NNP
cord-267965-84sotgds	255	37	et	et	NNP
cord-267965-84sotgds	255	38	al	al	NNP
cord-267965-84sotgds	255	39	.	.	NNP
cord-267965-84sotgds	255	40	,	,	,
cord-267965-84sotgds	255	41	2017	2017	CD
cord-267965-84sotgds	255	42	)	)	-RRB-
cord-267965-84sotgds	255	43	.	.	.
cord-267965-84sotgds	256	1	CC	CC	NNP
cord-267965-84sotgds	256	2	strains	strain	NNS
cord-267965-84sotgds	256	3	exhibited	exhibit	VBD
cord-267965-84sotgds	256	4	high	high	JJ
cord-267965-84sotgds	256	5	levels	level	NNS
cord-267965-84sotgds	256	6	of	of	IN
cord-267965-84sotgds	256	7	phenotypic	phenotypic	JJ
cord-267965-84sotgds	256	8	variation	variation	NN
cord-267965-84sotgds	256	9	that	that	WDT
cord-267965-84sotgds	256	10	extended	extend	VBD
cord-267965-84sotgds	256	11	well	well	RB
cord-267965-84sotgds	256	12	beyond	beyond	IN
cord-267965-84sotgds	256	13	the	the	DT
cord-267965-84sotgds	256	14	variation	variation	NN
cord-267965-84sotgds	256	15	observed	observe	VBN
cord-267965-84sotgds	256	16	between	between	IN
cord-267965-84sotgds	256	17	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	256	18	and	and	CC
cord-267965-84sotgds	256	19	BALB	BALB	NNP
cord-267965-84sotgds	256	20	/	/	SYM
cord-267965-84sotgds	256	21	c	c	NNP
cord-267965-84sotgds	256	22	,	,	,
cord-267965-84sotgds	256	23	the	the	DT
cord-267965-84sotgds	256	24	most	most	RBS
cord-267965-84sotgds	256	25	common	common	JJ
cord-267965-84sotgds	256	26	laboratory	laboratory	NN
cord-267965-84sotgds	256	27	strains	strain	NNS
cord-267965-84sotgds	256	28	in	in	IN
cord-267965-84sotgds	256	29	immunological	immunological	JJ
cord-267965-84sotgds	256	30	studies	study	NNS
cord-267965-84sotgds	256	31	.	.	.
cord-267965-84sotgds	257	1	Mapping	mapping	NN
cord-267965-84sotgds	257	2	identified	identify	VBD
cord-267965-84sotgds	257	3	two	two	CD
cord-267965-84sotgds	257	4	highly	highly	RB
cord-267965-84sotgds	257	5	significant	significant	JJ
cord-267965-84sotgds	257	6	QTLs	qtl	NNS
cord-267965-84sotgds	257	7	driving	drive	VBG
cord-267965-84sotgds	257	8	the	the	DT
cord-267965-84sotgds	257	9	frequency	frequency	NN
cord-267965-84sotgds	257	10	of	of	IN
cord-267965-84sotgds	257	11	specific	specific	JJ
cord-267965-84sotgds	257	12	T	T	NNP
cord-267965-84sotgds	257	13	regulatory	regulatory	JJ
cord-267965-84sotgds	257	14	subsets	subset	NNS
cord-267965-84sotgds	257	15	,	,	,
cord-267965-84sotgds	257	16	and	and	CC
cord-267965-84sotgds	257	17	candidates	candidate	NNS
cord-267965-84sotgds	257	18	were	be	VBD
cord-267965-84sotgds	257	19	chosen	choose	VBN
cord-267965-84sotgds	257	20	based	base	VBN
cord-267965-84sotgds	257	21	on	on	IN
cord-267965-84sotgds	257	22	concordance	concordance	NN
cord-267965-84sotgds	257	23	of	of	IN
cord-267965-84sotgds	257	24	haplotype	haplotype	NN
cord-267965-84sotgds	257	25	effects	effect	NNS
cord-267965-84sotgds	257	26	with	with	IN
cord-267965-84sotgds	257	27	founder	founder	NN
cord-267965-84sotgds	257	28	polymorphisms	polymorphism	NNS
cord-267965-84sotgds	257	29	that	that	WDT
cord-267965-84sotgds	257	30	were	be	VBD
cord-267965-84sotgds	257	31	coding	code	VBG
cord-267965-84sotgds	257	32	or	or	CC
cord-267965-84sotgds	257	33	splice	splice	NN
cord-267965-84sotgds	257	34	variants	variant	NNS
cord-267965-84sotgds	257	35	.	.	.
cord-267965-84sotgds	258	1	Similar	similar	JJ
cord-267965-84sotgds	258	2	to	to	IN
cord-267965-84sotgds	258	3	the	the	DT
cord-267965-84sotgds	258	4	cis	cis	NNP
cord-267965-84sotgds	258	5	-	-	HYPH
cord-267965-84sotgds	258	6	QTL	QTL	NNP
cord-267965-84sotgds	258	7	for	for	IN
cord-267965-84sotgds	258	8	CD23	CD23	NNP
cord-267965-84sotgds	258	9	expression	expression	NN
cord-267965-84sotgds	258	10	identified	identify	VBN
cord-267965-84sotgds	258	11	by	by	IN
cord-267965-84sotgds	258	12	Phillippi	Phillippi	NNP
cord-267965-84sotgds	258	13	et	et	NNP
cord-267965-84sotgds	258	14	al	al	NNP
cord-267965-84sotgds	258	15	.	.	NNP
cord-267965-84sotgds	258	16	,	,	,
cord-267965-84sotgds	258	17	the	the	DT
cord-267965-84sotgds	258	18	QTL	QTL	NNP
cord-267965-84sotgds	258	19	mapped	map	VBN
cord-267965-84sotgds	258	20	by	by	IN
cord-267965-84sotgds	258	21	Graham	Graham	NNP
cord-267965-84sotgds	258	22	et	et	NNP
cord-267965-84sotgds	258	23	al	al	NNP
cord-267965-84sotgds	258	24	.	.	.
cord-267965-84sotgds	259	1	for	for	IN
cord-267965-84sotgds	259	2	CXCR3	CXCR3	NNP
cord-267965-84sotgds	260	1	+	+	CC
cord-267965-84sotgds	261	1	T	T	NNP
cord-267965-84sotgds	261	2	regulatory	regulatory	JJ
cord-267965-84sotgds	261	3	cells	cell	NNS
cord-267965-84sotgds	261	4	contains	contain	VBZ
cord-267965-84sotgds	261	5	the	the	DT
cord-267965-84sotgds	261	6	Cxcr3	Cxcr3	NNP
cord-267965-84sotgds	261	7	gene	gene	NN
cord-267965-84sotgds	261	8	itself	-PRON-	PRP
cord-267965-84sotgds	261	9	.	.	.
cord-267965-84sotgds	262	1	Kri	Kri	NNP
cord-267965-84sotgds	262	2	sti	sti	NNP
cord-267965-84sotgds	262	3	c	c	NNP
cord-267965-84sotgds	262	4	et	et	NNP
cord-267965-84sotgds	262	5	al	al	NNP
cord-267965-84sotgds	262	6	.	.	.
cord-267965-84sotgds	263	1	studied	study	VBN
cord-267965-84sotgds	263	2	variation	variation	NN
cord-267965-84sotgds	263	3	in	in	IN
cord-267965-84sotgds	263	4	IgG	igg	NN
cord-267965-84sotgds	263	5	glycosylation	glycosylation	NN
cord-267965-84sotgds	263	6	,	,	,
cord-267965-84sotgds	263	7	which	which	WDT
cord-267965-84sotgds	263	8	is	be	VBZ
cord-267965-84sotgds	263	9	important	important	JJ
cord-267965-84sotgds	263	10	for	for	IN
cord-267965-84sotgds	263	11	antibody	antibody	NN
cord-267965-84sotgds	263	12	structure	structure	NN
cord-267965-84sotgds	263	13	and	and	CC
cord-267965-84sotgds	263	14	function	function	NN
cord-267965-84sotgds	263	15	,	,	,
cord-267965-84sotgds	263	16	in	in	IN
cord-267965-84sotgds	263	17	95	95	CD
cord-267965-84sotgds	263	18	CC	cc	NN
cord-267965-84sotgds	263	19	strains	strain	NNS
cord-267965-84sotgds	263	20	and	and	CC
cord-267965-84sotgds	263	21	observed	observe	VBD
cord-267965-84sotgds	263	22	nearly	nearly	RB
cord-267965-84sotgds	263	23	double	double	PDT
cord-267965-84sotgds	263	24	the	the	DT
cord-267965-84sotgds	263	25	variation	variation	NN
cord-267965-84sotgds	263	26	observed	observe	VBN
cord-267965-84sotgds	263	27	in	in	IN
cord-267965-84sotgds	263	28	humans	human	NNS
cord-267965-84sotgds	263	29	(	(	-LRB-
cord-267965-84sotgds	263	30	Kri	Kri	NNP
cord-267965-84sotgds	263	31	sti	sti	NNP
cord-267965-84sotgds	263	32	c	c	NNP
cord-267965-84sotgds	263	33	et	et	NNP
cord-267965-84sotgds	263	34	al	al	NNP
cord-267965-84sotgds	263	35	.	.	NNP
cord-267965-84sotgds	263	36	,	,	,
cord-267965-84sotgds	263	37	2018	2018	CD
cord-267965-84sotgds	263	38	)	)	-RRB-
cord-267965-84sotgds	263	39	.	.	.
cord-267965-84sotgds	264	1	Glycosylation	glycosylation	NN
cord-267965-84sotgds	264	2	patterns	pattern	NNS
cord-267965-84sotgds	264	3	were	be	VBD
cord-267965-84sotgds	264	4	up	up	RB
cord-267965-84sotgds	264	5	to	to	TO
cord-267965-84sotgds	264	6	80	80	CD
cord-267965-84sotgds	264	7	%	%	NN
cord-267965-84sotgds	264	8	heritable	heritable	JJ
cord-267965-84sotgds	264	9	,	,	,
cord-267965-84sotgds	264	10	and	and	CC
cord-267965-84sotgds	264	11	multiple	multiple	JJ
cord-267965-84sotgds	264	12	QTLs	qtl	NNS
cord-267965-84sotgds	264	13	associated	associate	VBN
cord-267965-84sotgds	264	14	with	with	IN
cord-267965-84sotgds	264	15	variation	variation	NN
cord-267965-84sotgds	264	16	in	in	IN
cord-267965-84sotgds	264	17	different	different	JJ
cord-267965-84sotgds	264	18	glycans	glycan	NNS
cord-267965-84sotgds	264	19	were	be	VBD
cord-267965-84sotgds	264	20	identified	identify	VBN
cord-267965-84sotgds	264	21	.	.	.
cord-267965-84sotgds	265	1	Variation	variation	NN
cord-267965-84sotgds	265	2	in	in	IN
cord-267965-84sotgds	265	3	5	5	CD
cord-267965-84sotgds	265	4	different	different	JJ
cord-267965-84sotgds	265	5	glycans	glycan	NNS
cord-267965-84sotgds	265	6	all	all	DT
cord-267965-84sotgds	265	7	mapped	map	VBN
cord-267965-84sotgds	265	8	to	to	IN
cord-267965-84sotgds	265	9	the	the	DT
cord-267965-84sotgds	265	10	immunoglobulin	immunoglobulin	NN
cord-267965-84sotgds	265	11	heavy	heavy	JJ
cord-267965-84sotgds	265	12	chain	chain	NN
cord-267965-84sotgds	265	13	locus	locus	NN
cord-267965-84sotgds	265	14	.	.	.
cord-267965-84sotgds	266	1	Variation	variation	NN
cord-267965-84sotgds	266	2	in	in	IN
cord-267965-84sotgds	266	3	2	2	CD
cord-267965-84sotgds	266	4	other	other	JJ
cord-267965-84sotgds	266	5	glycans	glycan	NNS
cord-267965-84sotgds	266	6	mapped	map	VBN
cord-267965-84sotgds	266	7	to	to	IN
cord-267965-84sotgds	266	8	a	a	DT
cord-267965-84sotgds	266	9	locus	locus	NN
cord-267965-84sotgds	266	10	containing	contain	VBG
cord-267965-84sotgds	266	11	the	the	DT
cord-267965-84sotgds	266	12	glycosyltransferaseencoding	glycosyltransferaseencode	VBG
cord-267965-84sotgds	266	13	gene	gene	NN
cord-267965-84sotgds	266	14	Mgat3	Mgat3	NNP
cord-267965-84sotgds	266	15	,	,	,
cord-267965-84sotgds	266	16	which	which	WDT
cord-267965-84sotgds	266	17	was	be	VBD
cord-267965-84sotgds	266	18	identified	identify	VBN
cord-267965-84sotgds	266	19	as	as	IN
cord-267965-84sotgds	266	20	a	a	DT
cord-267965-84sotgds	266	21	strong	strong	JJ
cord-267965-84sotgds	266	22	candidate	candidate	NN
cord-267965-84sotgds	266	23	.	.	.
cord-267965-84sotgds	267	1	Commensals	Commensals	NNP
cord-267965-84sotgds	267	2	and	and	CC
cord-267965-84sotgds	267	3	the	the	DT
cord-267965-84sotgds	267	4	Microbiome	Microbiome	NNP
cord-267965-84sotgds	267	5	in	in	IN
cord-267965-84sotgds	267	6	the	the	DT
cord-267965-84sotgds	267	7	CC	cc	NN
cord-267965-84sotgds	268	1	While	while	IN
cord-267965-84sotgds	268	2	the	the	DT
cord-267965-84sotgds	268	3	focus	focus	NN
cord-267965-84sotgds	268	4	of	of	IN
cord-267965-84sotgds	268	5	this	this	DT
cord-267965-84sotgds	268	6	review	review	NN
cord-267965-84sotgds	268	7	is	be	VBZ
cord-267965-84sotgds	268	8	on	on	IN
cord-267965-84sotgds	268	9	genetic	genetic	JJ
cord-267965-84sotgds	268	10	control	control	NN
cord-267965-84sotgds	268	11	of	of	IN
cord-267965-84sotgds	268	12	immune	immune	JJ
cord-267965-84sotgds	268	13	populations	population	NNS
cord-267965-84sotgds	268	14	and	and	CC
cord-267965-84sotgds	268	15	response	response	NN
cord-267965-84sotgds	268	16	to	to	IN
cord-267965-84sotgds	268	17	infectious	infectious	JJ
cord-267965-84sotgds	268	18	agents	agent	NNS
cord-267965-84sotgds	268	19	,	,	,
cord-267965-84sotgds	268	20	there	there	EX
cord-267965-84sotgds	268	21	is	be	VBZ
cord-267965-84sotgds	268	22	a	a	DT
cord-267965-84sotgds	268	23	growing	grow	VBG
cord-267965-84sotgds	268	24	appreciation	appreciation	NN
cord-267965-84sotgds	268	25	for	for	IN
cord-267965-84sotgds	268	26	the	the	DT
cord-267965-84sotgds	268	27	role	role	NN
cord-267965-84sotgds	268	28	commensals	commensal	NNS
cord-267965-84sotgds	268	29	play	play	VBP
cord-267965-84sotgds	268	30	in	in	IN
cord-267965-84sotgds	268	31	shaping	shape	VBG
cord-267965-84sotgds	268	32	health	health	NN
cord-267965-84sotgds	268	33	and	and	CC
cord-267965-84sotgds	268	34	modulating	modulate	VBG
cord-267965-84sotgds	268	35	immune	immune	JJ
cord-267965-84sotgds	268	36	responses	response	NNS
cord-267965-84sotgds	268	37	.	.	.
cord-267965-84sotgds	269	1	Two	two	CD
cord-267965-84sotgds	269	2	studies	study	NNS
cord-267965-84sotgds	269	3	have	have	VBP
cord-267965-84sotgds	269	4	addressed	address	VBN
cord-267965-84sotgds	269	5	these	these	DT
cord-267965-84sotgds	269	6	responses	response	NNS
cord-267965-84sotgds	269	7	in	in	IN
cord-267965-84sotgds	269	8	the	the	DT
cord-267965-84sotgds	269	9	CC	cc	NN
cord-267965-84sotgds	270	1	(	(	-LRB-
cord-267965-84sotgds	270	2	Snijders	Snijders	NNP
cord-267965-84sotgds	270	3	et	et	NNP
cord-267965-84sotgds	270	4	al	al	NNP
cord-267965-84sotgds	270	5	.	.	NNP
cord-267965-84sotgds	270	6	,	,	,
cord-267965-84sotgds	270	7	2016	2016	CD
cord-267965-84sotgds	270	8	)	)	-RRB-
cord-267965-84sotgds	270	9	and	and	CC
cord-267965-84sotgds	270	10	DO	do	VB
cord-267965-84sotgds	270	11	(	(	-LRB-
cord-267965-84sotgds	270	12	Carmody	Carmody	NNP
cord-267965-84sotgds	270	13	et	et	NNP
cord-267965-84sotgds	270	14	al	al	NNP
cord-267965-84sotgds	270	15	.	.	NNP
cord-267965-84sotgds	270	16	,	,	,
cord-267965-84sotgds	270	17	2015	2015	CD
cord-267965-84sotgds	270	18	)	)	-RRB-
cord-267965-84sotgds	270	19	populations	population	NNS
cord-267965-84sotgds	270	20	.	.	.
cord-267965-84sotgds	271	1	Both	both	DT
cord-267965-84sotgds	271	2	found	find	VBD
cord-267965-84sotgds	271	3	that	that	IN
cord-267965-84sotgds	271	4	there	there	EX
cord-267965-84sotgds	271	5	were	be	VBD
cord-267965-84sotgds	271	6	significant	significant	JJ
cord-267965-84sotgds	271	7	contributions	contribution	NNS
cord-267965-84sotgds	271	8	of	of	IN
cord-267965-84sotgds	271	9	host	host	NN
cord-267965-84sotgds	271	10	genetic	genetic	JJ
cord-267965-84sotgds	271	11	backgrounds	background	NNS
cord-267965-84sotgds	271	12	.	.	.
cord-267965-84sotgds	272	1	Further	further	RB
cord-267965-84sotgds	272	2	,	,	,
cord-267965-84sotgds	272	3	the	the	DT
cord-267965-84sotgds	272	4	CC	CC	NNP
cord-267965-84sotgds	272	5	study	study	NN
cord-267965-84sotgds	272	6	found	find	VBD
cord-267965-84sotgds	272	7	strong	strong	JJ
cord-267965-84sotgds	272	8	genomic	genomic	JJ
cord-267965-84sotgds	272	9	signals	signal	NNS
cord-267965-84sotgds	272	10	for	for	IN
cord-267965-84sotgds	272	11	many	many	JJ
cord-267965-84sotgds	272	12	bacterial	bacterial	JJ
cord-267965-84sotgds	272	13	groups	group	NNS
cord-267965-84sotgds	272	14	(	(	-LRB-
cord-267965-84sotgds	272	15	OTUs	OTUs	NNPS
cord-267965-84sotgds	272	16	)	)	-RRB-
cord-267965-84sotgds	272	17	around	around	IN
cord-267965-84sotgds	272	18	the	the	DT
cord-267965-84sotgds	272	19	genome	genome	NN
cord-267965-84sotgds	272	20	.	.	.
cord-267965-84sotgds	273	1	Given	give	VBN
cord-267965-84sotgds	273	2	the	the	DT
cord-267965-84sotgds	273	3	increasing	increase	VBG
cord-267965-84sotgds	273	4	appreciation	appreciation	NN
cord-267965-84sotgds	273	5	and	and	CC
cord-267965-84sotgds	273	6	awareness	awareness	NN
cord-267965-84sotgds	273	7	of	of	IN
cord-267965-84sotgds	273	8	the	the	DT
cord-267965-84sotgds	273	9	microbiome	microbiome	NN
cord-267965-84sotgds	273	10	in	in	IN
cord-267965-84sotgds	273	11	modulating	modulate	VBG
cord-267965-84sotgds	273	12	a	a	DT
cord-267965-84sotgds	273	13	variety	variety	NN
cord-267965-84sotgds	273	14	of	of	IN
cord-267965-84sotgds	273	15	biomedically	biomedically	RB
cord-267965-84sotgds	273	16	relevant	relevant	JJ
cord-267965-84sotgds	273	17	traits	trait	NNS
cord-267965-84sotgds	273	18	,	,	,
cord-267965-84sotgds	273	19	as	as	RB
cord-267965-84sotgds	273	20	well	well	RB
cord-267965-84sotgds	273	21	as	as	IN
cord-267965-84sotgds	273	22	the	the	DT
cord-267965-84sotgds	273	23	impact	impact	NN
cord-267965-84sotgds	273	24	of	of	IN
cord-267965-84sotgds	273	25	commensals	commensal	NNS
cord-267965-84sotgds	273	26	and	and	CC
cord-267965-84sotgds	273	27	the	the	DT
cord-267965-84sotgds	273	28	virome	virome	NN
cord-267965-84sotgds	273	29	(	(	-LRB-
cord-267965-84sotgds	273	30	Virgin	Virgin	NNP
cord-267965-84sotgds	273	31	,	,	,
cord-267965-84sotgds	273	32	2014	2014	CD
cord-267965-84sotgds	273	33	)	)	-RRB-
cord-267965-84sotgds	273	34	on	on	IN
cord-267965-84sotgds	273	35	directly	directly	RB
cord-267965-84sotgds	273	36	modulating	modulate	VBG
cord-267965-84sotgds	273	37	immune	immune	JJ
cord-267965-84sotgds	273	38	responses	response	NNS
cord-267965-84sotgds	273	39	(	(	-LRB-
cord-267965-84sotgds	273	40	Masopust	Masopust	NNP
cord-267965-84sotgds	273	41	et	et	NNP
cord-267965-84sotgds	273	42	al	al	NNP
cord-267965-84sotgds	273	43	.	.	NNP
cord-267965-84sotgds	273	44	,	,	,
cord-267965-84sotgds	273	45	2017	2017	CD
cord-267965-84sotgds	273	46	)	)	-RRB-
cord-267965-84sotgds	273	47	,	,	,
cord-267965-84sotgds	273	48	future	future	JJ
cord-267965-84sotgds	273	49	work	work	NN
cord-267965-84sotgds	273	50	within	within	IN
cord-267965-84sotgds	273	51	the	the	DT
cord-267965-84sotgds	273	52	CC	CC	NNP
cord-267965-84sotgds	273	53	will	will	MD
cord-267965-84sotgds	273	54	allow	allow	VB
cord-267965-84sotgds	273	55	for	for	IN
cord-267965-84sotgds	273	56	the	the	DT
cord-267965-84sotgds	273	57	disentangling	disentangling	NN
cord-267965-84sotgds	273	58	of	of	IN
cord-267965-84sotgds	273	59	direct	direct	JJ
cord-267965-84sotgds	273	60	roles	role	NNS
cord-267965-84sotgds	273	61	on	on	IN
cord-267965-84sotgds	273	62	host	host	JJ
cord-267965-84sotgds	273	63	genetic	genetic	JJ
cord-267965-84sotgds	273	64	variants	variant	NNS
cord-267965-84sotgds	273	65	on	on	IN
cord-267965-84sotgds	273	66	disease	disease	NN
cord-267965-84sotgds	273	67	responses	response	NNS
cord-267965-84sotgds	273	68	,	,	,
cord-267965-84sotgds	273	69	as	as	RB
cord-267965-84sotgds	273	70	well	well	RB
cord-267965-84sotgds	273	71	as	as	IN
cord-267965-84sotgds	273	72	indirect	indirect	JJ
cord-267965-84sotgds	273	73	roles	role	NNS
cord-267965-84sotgds	273	74	mediated	mediate	VBN
cord-267965-84sotgds	273	75	through	through	IN
cord-267965-84sotgds	273	76	effects	effect	NNS
cord-267965-84sotgds	273	77	on	on	IN
cord-267965-84sotgds	273	78	commensals	commensal	NNS
cord-267965-84sotgds	273	79	or	or	CC
cord-267965-84sotgds	273	80	prior	prior	JJ
cord-267965-84sotgds	273	81	immune	immune	JJ
cord-267965-84sotgds	273	82	exposure	exposure	NN
cord-267965-84sotgds	273	83	.	.	.
cord-267965-84sotgds	274	1	The	the	DT
cord-267965-84sotgds	274	2	CC	CC	NNP
cord-267965-84sotgds	274	3	is	be	VBZ
cord-267965-84sotgds	274	4	a	a	DT
cord-267965-84sotgds	274	5	powerful	powerful	JJ
cord-267965-84sotgds	274	6	resource	resource	NN
cord-267965-84sotgds	274	7	for	for	IN
cord-267965-84sotgds	274	8	model	model	NN
cord-267965-84sotgds	274	9	development	development	NN
cord-267965-84sotgds	274	10	,	,	,
cord-267965-84sotgds	274	11	extreme	extreme	JJ
cord-267965-84sotgds	274	12	phenotype	phenotype	NN
cord-267965-84sotgds	274	13	discovery	discovery	NN
cord-267965-84sotgds	274	14	,	,	,
cord-267965-84sotgds	274	15	population	population	NN
cord-267965-84sotgds	274	16	-	-	HYPH
cord-267965-84sotgds	274	17	based	base	VBN
cord-267965-84sotgds	274	18	QTL	QTL	NNP
cord-267965-84sotgds	274	19	mapping	mapping	NN
cord-267965-84sotgds	274	20	,	,	,
cord-267965-84sotgds	274	21	intercross	intercross	NNP
cord-267965-84sotgds	274	22	mapping	mapping	NN
cord-267965-84sotgds	274	23	,	,	,
cord-267965-84sotgds	274	24	validation	validation	NN
cord-267965-84sotgds	274	25	of	of	IN
cord-267965-84sotgds	274	26	candidate	candidate	NN
cord-267965-84sotgds	274	27	genes	gene	NNS
cord-267965-84sotgds	274	28	across	across	IN
cord-267965-84sotgds	274	29	genetic	genetic	JJ
cord-267965-84sotgds	274	30	backgrounds	background	NNS
cord-267965-84sotgds	274	31	,	,	,
cord-267965-84sotgds	274	32	and	and	CC
cord-267965-84sotgds	274	33	a	a	DT
cord-267965-84sotgds	274	34	variety	variety	NN
cord-267965-84sotgds	274	35	of	of	IN
cord-267965-84sotgds	274	36	other	other	JJ
cord-267965-84sotgds	274	37	approaches	approach	NNS
cord-267965-84sotgds	274	38	.	.	.
cord-267965-84sotgds	275	1	Here	here	RB
cord-267965-84sotgds	275	2	,	,	,
cord-267965-84sotgds	275	3	we	-PRON-	PRP
cord-267965-84sotgds	275	4	provide	provide	VBP
cord-267965-84sotgds	275	5	an	an	DT
cord-267965-84sotgds	275	6	overview	overview	NN
cord-267965-84sotgds	275	7	of	of	IN
cord-267965-84sotgds	275	8	different	different	JJ
cord-267965-84sotgds	275	9	study	study	NN
cord-267965-84sotgds	275	10	designs	design	NNS
cord-267965-84sotgds	275	11	that	that	WDT
cord-267965-84sotgds	275	12	can	can	MD
cord-267965-84sotgds	275	13	be	be	VB
cord-267965-84sotgds	275	14	implemented	implement	VBN
cord-267965-84sotgds	275	15	to	to	TO
cord-267965-84sotgds	275	16	study	study	VB
cord-267965-84sotgds	275	17	the	the	DT
cord-267965-84sotgds	275	18	impact	impact	NN
cord-267965-84sotgds	275	19	of	of	IN
cord-267965-84sotgds	275	20	host	host	JJ
cord-267965-84sotgds	275	21	genetic	genetic	JJ
cord-267965-84sotgds	275	22	variation	variation	NN
cord-267965-84sotgds	275	23	on	on	IN
cord-267965-84sotgds	275	24	pathogen	pathogen	NN
cord-267965-84sotgds	275	25	outcomes	outcome	NNS
cord-267965-84sotgds	275	26	or	or	CC
cord-267965-84sotgds	275	27	immunity	immunity	NN
cord-267965-84sotgds	275	28	using	use	VBG
cord-267965-84sotgds	275	29	the	the	DT
cord-267965-84sotgds	275	30	CC	CC	NNP
cord-267965-84sotgds	275	31	(	(	-LRB-
cord-267965-84sotgds	275	32	Figure	figure	NN
cord-267965-84sotgds	275	33	3	3	CD
cord-267965-84sotgds	275	34	)	)	-RRB-
cord-267965-84sotgds	275	35	.	.	.
cord-267965-84sotgds	276	1	Many	many	JJ
cord-267965-84sotgds	276	2	of	of	IN
cord-267965-84sotgds	276	3	the	the	DT
cord-267965-84sotgds	276	4	genetic	genetic	JJ
cord-267965-84sotgds	276	5	mapping	mapping	NN
cord-267965-84sotgds	276	6	studies	study	NNS
cord-267965-84sotgds	276	7	described	describe	VBN
cord-267965-84sotgds	276	8	above	above	RB
cord-267965-84sotgds	276	9	utilized	utilize	VBN
cord-267965-84sotgds	276	10	large	large	JJ
cord-267965-84sotgds	276	11	panels	panel	NNS
cord-267965-84sotgds	276	12	of	of	IN
cord-267965-84sotgds	276	13	CC	cc	NN
cord-267965-84sotgds	276	14	strains	strain	NNS
cord-267965-84sotgds	276	15	and	and	CC
cord-267965-84sotgds	276	16	were	be	VBD
cord-267965-84sotgds	276	17	able	able	JJ
cord-267965-84sotgds	276	18	to	to	TO
cord-267965-84sotgds	276	19	identify	identify	VB
cord-267965-84sotgds	276	20	loci	locus	NNS
cord-267965-84sotgds	276	21	of	of	IN
cord-267965-84sotgds	276	22	moderate	moderate	JJ
cord-267965-84sotgds	276	23	to	to	IN
cord-267965-84sotgds	276	24	large	large	JJ
cord-267965-84sotgds	276	25	effects	effect	NNS
cord-267965-84sotgds	276	26	on	on	IN
cord-267965-84sotgds	276	27	pathogen	pathogen	NN
cord-267965-84sotgds	276	28	outcomes	outcome	NNS
cord-267965-84sotgds	276	29	.	.	.
cord-267965-84sotgds	277	1	However	however	RB
cord-267965-84sotgds	277	2	,	,	,
cord-267965-84sotgds	277	3	these	these	DT
cord-267965-84sotgds	277	4	types	type	NNS
cord-267965-84sotgds	277	5	of	of	IN
cord-267965-84sotgds	277	6	studies	study	NNS
cord-267965-84sotgds	277	7	are	be	VBP
cord-267965-84sotgds	277	8	extremely	extremely	RB
cord-267965-84sotgds	277	9	resource	resource	NN
cord-267965-84sotgds	277	10	intensive	intensive	JJ
cord-267965-84sotgds	277	11	and	and	CC
cord-267965-84sotgds	277	12	may	may	MD
cord-267965-84sotgds	277	13	not	not	RB
cord-267965-84sotgds	277	14	always	always	RB
cord-267965-84sotgds	277	15	be	be	VB
cord-267965-84sotgds	277	16	the	the	DT
cord-267965-84sotgds	277	17	optimal	optimal	JJ
cord-267965-84sotgds	277	18	approach	approach	NN
cord-267965-84sotgds	277	19	.	.	.
cord-267965-84sotgds	278	1	Rather	rather	RB
cord-267965-84sotgds	278	2	,	,	,
cord-267965-84sotgds	278	3	we	-PRON-	PRP
cord-267965-84sotgds	278	4	suggest	suggest	VBP
cord-267965-84sotgds	278	5	a	a	DT
cord-267965-84sotgds	278	6	tiered	tiered	JJ
cord-267965-84sotgds	278	7	approach	approach	NN
cord-267965-84sotgds	278	8	to	to	TO
cord-267965-84sotgds	278	9	study	study	VB
cord-267965-84sotgds	278	10	design	design	NN
cord-267965-84sotgds	278	11	within	within	IN
cord-267965-84sotgds	278	12	the	the	DT
cord-267965-84sotgds	278	13	CC	cc	NN
cord-267965-84sotgds	278	14	,	,	,
cord-267965-84sotgds	278	15	starting	start	VBG
cord-267965-84sotgds	278	16	with	with	IN
cord-267965-84sotgds	278	17	a	a	DT
cord-267965-84sotgds	278	18	small	small	JJ
cord-267965-84sotgds	278	19	-	-	HYPH
cord-267965-84sotgds	278	20	scale	scale	NN
cord-267965-84sotgds	278	21	analysis	analysis	NN
cord-267965-84sotgds	278	22	in	in	IN
cord-267965-84sotgds	278	23	a	a	DT
cord-267965-84sotgds	278	24	set	set	NN
cord-267965-84sotgds	278	25	of	of	IN
cord-267965-84sotgds	278	26	strains	strain	NNS
cord-267965-84sotgds	278	27	(	(	-LRB-
cord-267965-84sotgds	278	28	e.g.	e.g.	RB
cord-267965-84sotgds	278	29	,	,	,
cord-267965-84sotgds	278	30	12	12	CD
cord-267965-84sotgds	278	31	-	-	SYM
cord-267965-84sotgds	278	32	16	16	CD
cord-267965-84sotgds	278	33	)	)	-RRB-
cord-267965-84sotgds	278	34	that	that	IN
cord-267965-84sotgds	278	35	sample	sample	NN
cord-267965-84sotgds	278	36	most	most	JJS
cord-267965-84sotgds	278	37	of	of	IN
cord-267965-84sotgds	278	38	the	the	DT
cord-267965-84sotgds	278	39	haplotypes	haplotype	NNS
cord-267965-84sotgds	278	40	present	present	JJ
cord-267965-84sotgds	278	41	across	across	IN
cord-267965-84sotgds	278	42	the	the	DT
cord-267965-84sotgds	278	43	CC	cc	NN
cord-267965-84sotgds	278	44	genomes	genome	NNS
cord-267965-84sotgds	278	45	,	,	,
cord-267965-84sotgds	278	46	and	and	CC
cord-267965-84sotgds	278	47	expanding	expand	VBG
cord-267965-84sotgds	278	48	as	as	RB
cord-267965-84sotgds	278	49	necessary	necessary	JJ
cord-267965-84sotgds	278	50	.	.	.
cord-267965-84sotgds	279	1	The	the	DT
cord-267965-84sotgds	279	2	efficacy	efficacy	NN
cord-267965-84sotgds	279	3	of	of	IN
cord-267965-84sotgds	279	4	this	this	DT
cord-267965-84sotgds	279	5	type	type	NN
cord-267965-84sotgds	279	6	of	of	IN
cord-267965-84sotgds	279	7	approach	approach	NN
cord-267965-84sotgds	279	8	is	be	VBZ
cord-267965-84sotgds	279	9	demonstrated	demonstrate	VBN
cord-267965-84sotgds	279	10	by	by	IN
cord-267965-84sotgds	279	11	the	the	DT
cord-267965-84sotgds	279	12	success	success	NN
cord-267965-84sotgds	279	13	of	of	IN
cord-267965-84sotgds	279	14	small	small	JJ
cord-267965-84sotgds	279	15	CC	cc	NN
cord-267965-84sotgds	279	16	screens	screen	NNS
cord-267965-84sotgds	279	17	that	that	WDT
cord-267965-84sotgds	279	18	have	have	VBP
cord-267965-84sotgds	279	19	identified	identify	VBN
cord-267965-84sotgds	279	20	strains	strain	NNS
cord-267965-84sotgds	279	21	with	with	IN
cord-267965-84sotgds	279	22	unique	unique	JJ
cord-267965-84sotgds	279	23	phenotypes	phenotype	NNS
cord-267965-84sotgds	279	24	and	and	CC
cord-267965-84sotgds	279	25	proceeded	proceed	VBD
cord-267965-84sotgds	279	26	with	with	IN
cord-267965-84sotgds	279	27	further	further	JJ
cord-267965-84sotgds	279	28	targeted	target	VBN
cord-267965-84sotgds	279	29	studies	study	NNS
cord-267965-84sotgds	279	30	such	such	JJ
cord-267965-84sotgds	279	31	as	as	IN
cord-267965-84sotgds	279	32	F2	f2	NN
cord-267965-84sotgds	279	33	crosses	cross	VBZ
cord-267965-84sotgds	279	34	to	to	TO
cord-267965-84sotgds	279	35	reveal	reveal	VB
cord-267965-84sotgds	279	36	complex	complex	JJ
cord-267965-84sotgds	279	37	polygenic	polygenic	JJ
cord-267965-84sotgds	279	38	networks	network	NNS
cord-267965-84sotgds	279	39	driving	drive	VBG
cord-267965-84sotgds	279	40	the	the	DT
cord-267965-84sotgds	279	41	outlier	outlier	JJ
cord-267965-84sotgds	279	42	phenotype	phenotype	NN
cord-267965-84sotgds	279	43	(	(	-LRB-
cord-267965-84sotgds	279	44	Gralinski	Gralinski	NNP
cord-267965-84sotgds	279	45	et	et	FW
cord-267965-84sotgds	279	46	al	al	NNP
cord-267965-84sotgds	279	47	.	.	NNP
cord-267965-84sotgds	279	48	,	,	,
cord-267965-84sotgds	279	49	2017	2017	CD
cord-267965-84sotgds	279	50	;	;	:
cord-267965-84sotgds	279	51	Rogala	Rogala	NNP
cord-267965-84sotgds	279	52	et	et	FW
cord-267965-84sotgds	279	53	al	al	NNP
cord-267965-84sotgds	279	54	.	.	NNP
cord-267965-84sotgds	279	55	,	,	,
cord-267965-84sotgds	279	56	2014	2014	CD
cord-267965-84sotgds	279	57	)	)	-RRB-
cord-267965-84sotgds	279	58	.	.	.
cord-267965-84sotgds	280	1	Furthermore	furthermore	RB
cord-267965-84sotgds	280	2	,	,	,
cord-267965-84sotgds	280	3	even	even	RB
cord-267965-84sotgds	280	4	when	when	WRB
cord-267965-84sotgds	280	5	investigators	investigator	NNS
cord-267965-84sotgds	280	6	opt	opt	VBP
cord-267965-84sotgds	280	7	for	for	IN
cord-267965-84sotgds	280	8	large	large	JJ
cord-267965-84sotgds	280	9	mapping	mapping	NN
cord-267965-84sotgds	280	10	studies	study	NNS
cord-267965-84sotgds	280	11	,	,	,
cord-267965-84sotgds	280	12	they	-PRON-	PRP
cord-267965-84sotgds	280	13	may	may	MD
cord-267965-84sotgds	280	14	still	still	RB
cord-267965-84sotgds	280	15	identify	identify	VB
cord-267965-84sotgds	280	16	strains	strain	NNS
cord-267965-84sotgds	280	17	with	with	IN
cord-267965-84sotgds	280	18	unique	unique	JJ
cord-267965-84sotgds	280	19	outlier	outlier	JJ
cord-267965-84sotgds	280	20	phenotypes	phenotype	NNS
cord-267965-84sotgds	280	21	that	that	WDT
cord-267965-84sotgds	280	22	can	can	MD
cord-267965-84sotgds	280	23	not	not	RB
cord-267965-84sotgds	280	24	be	be	VB
cord-267965-84sotgds	280	25	explained	explain	VBN
cord-267965-84sotgds	280	26	by	by	IN
cord-267965-84sotgds	280	27	QTLs	qtl	NNS
cord-267965-84sotgds	280	28	identified	identify	VBN
cord-267965-84sotgds	280	29	in	in	IN
cord-267965-84sotgds	280	30	the	the	DT
cord-267965-84sotgds	280	31	initial	initial	JJ
cord-267965-84sotgds	280	32	screen	screen	NN
cord-267965-84sotgds	280	33	.	.	.
cord-267965-84sotgds	281	1	This	this	DT
cord-267965-84sotgds	281	2	missing	miss	VBG
cord-267965-84sotgds	281	3	heritability	heritability	NN
cord-267965-84sotgds	281	4	may	may	MD
cord-267965-84sotgds	281	5	be	be	VB
cord-267965-84sotgds	281	6	driven	drive	VBN
cord-267965-84sotgds	281	7	by	by	IN
cord-267965-84sotgds	281	8	complex	complex	JJ
cord-267965-84sotgds	281	9	genetic	genetic	JJ
cord-267965-84sotgds	281	10	interactions	interaction	NNS
cord-267965-84sotgds	281	11	such	such	JJ
cord-267965-84sotgds	281	12	as	as	IN
cord-267965-84sotgds	281	13	epistasis	epistasis	NN
cord-267965-84sotgds	281	14	,	,	,
cord-267965-84sotgds	281	15	which	which	WDT
cord-267965-84sotgds	281	16	are	be	VBP
cord-267965-84sotgds	281	17	difficult	difficult	JJ
cord-267965-84sotgds	281	18	to	to	TO
cord-267965-84sotgds	281	19	study	study	VB
cord-267965-84sotgds	281	20	in	in	IN
cord-267965-84sotgds	281	21	complex	complex	JJ
cord-267965-84sotgds	281	22	populations	population	NNS
cord-267965-84sotgds	281	23	and	and	CC
cord-267965-84sotgds	281	24	are	be	VBP
cord-267965-84sotgds	281	25	more	more	RBR
cord-267965-84sotgds	281	26	effectively	effectively	RB
cord-267965-84sotgds	281	27	studied	study	VBN
cord-267965-84sotgds	281	28	in	in	IN
cord-267965-84sotgds	281	29	targeted	target	VBN
cord-267965-84sotgds	281	30	crosses	crosse	NNS
cord-267965-84sotgds	282	1	(	(	-LRB-
cord-267965-84sotgds	282	2	Rogala	Rogala	NNP
cord-267965-84sotgds	282	3	et	et	FW
cord-267965-84sotgds	282	4	al	al	NNP
cord-267965-84sotgds	282	5	.	.	NNP
cord-267965-84sotgds	282	6	,	,	,
cord-267965-84sotgds	282	7	2014	2014	CD
cord-267965-84sotgds	282	8	)	)	-RRB-
cord-267965-84sotgds	282	9	.	.	.
cord-267965-84sotgds	283	1	Initially	initially	RB
cord-267965-84sotgds	283	2	screening	screen	VBG
cord-267965-84sotgds	283	3	small	small	JJ
cord-267965-84sotgds	283	4	sets	set	NNS
cord-267965-84sotgds	283	5	of	of	IN
cord-267965-84sotgds	283	6	CC	cc	NN
cord-267965-84sotgds	283	7	strains	strain	NNS
cord-267965-84sotgds	283	8	(	(	-LRB-
cord-267965-84sotgds	283	9	e.g.	e.g.	RB
cord-267965-84sotgds	283	10	,	,	,
cord-267965-84sotgds	283	11	12	12	CD
cord-267965-84sotgds	283	12	-	-	SYM
cord-267965-84sotgds	283	13	16	16	CD
cord-267965-84sotgds	283	14	)	)	-RRB-
cord-267965-84sotgds	283	15	allows	allow	VBZ
cord-267965-84sotgds	283	16	the	the	DT
cord-267965-84sotgds	283	17	investigator	investigator	NN
cord-267965-84sotgds	283	18	to	to	TO
cord-267965-84sotgds	283	19	obtain	obtain	VB
cord-267965-84sotgds	283	20	insight	insight	NN
cord-267965-84sotgds	283	21	into	into	IN
cord-267965-84sotgds	283	22	the	the	DT
cord-267965-84sotgds	283	23	distribution	distribution	NN
cord-267965-84sotgds	283	24	of	of	IN
cord-267965-84sotgds	283	25	trait	trait	NN
cord-267965-84sotgds	283	26	variation	variation	NN
cord-267965-84sotgds	283	27	(	(	-LRB-
cord-267965-84sotgds	283	28	e.g.	e.g.	RB
cord-267965-84sotgds	283	29	,	,	,
cord-267965-84sotgds	283	30	continuous	continuous	JJ
cord-267965-84sotgds	283	31	,	,	,
cord-267965-84sotgds	283	32	bimodal	bimodal	JJ
cord-267965-84sotgds	283	33	)	)	-RRB-
cord-267965-84sotgds	283	34	,	,	,
cord-267965-84sotgds	283	35	while	while	IN
cord-267965-84sotgds	283	36	testing	test	VBG
cord-267965-84sotgds	283	37	whether	whether	IN
cord-267965-84sotgds	283	38	any	any	DT
cord-267965-84sotgds	283	39	strains	strain	NNS
cord-267965-84sotgds	283	40	show	show	VBP
cord-267965-84sotgds	283	41	unique	unique	JJ
cord-267965-84sotgds	283	42	or	or	CC
cord-267965-84sotgds	283	43	strong	strong	JJ
cord-267965-84sotgds	283	44	outlier	outlier	JJ
cord-267965-84sotgds	283	45	phenotypes	phenotype	NNS
cord-267965-84sotgds	283	46	(	(	-LRB-
cord-267965-84sotgds	284	1	Gralinski	Gralinski	NNP
cord-267965-84sotgds	284	2	et	et	FW
cord-267965-84sotgds	284	3	al	al	NNP
cord-267965-84sotgds	284	4	.	.	NNP
cord-267965-84sotgds	284	5	,	,	,
cord-267965-84sotgds	284	6	2015	2015	CD
cord-267965-84sotgds	285	1	;	;	:
cord-267965-84sotgds	285	2	Rasmussen	Rasmussen	NNP
cord-267965-84sotgds	285	3	et	et	NNP
cord-267965-84sotgds	285	4	al	al	NNP
cord-267965-84sotgds	285	5	.	.	.
cord-267965-84sotgds	286	1	,	,	,
cord-267965-84sotgds	286	2	2014	2014	CD
cord-267965-84sotgds	286	3	;	;	:
cord-267965-84sotgds	286	4	Rogala	Rogala	NNP
cord-267965-84sotgds	286	5	et	et	FW
cord-267965-84sotgds	286	6	al	al	NNP
cord-267965-84sotgds	286	7	.	.	.
cord-267965-84sotgds	287	1	,	,	,
cord-267965-84sotgds	287	2	2014	2014	CD
cord-267965-84sotgds	287	3	)	)	-RRB-
cord-267965-84sotgds	287	4	.	.	.
cord-267965-84sotgds	288	1	These	these	DT
cord-267965-84sotgds	288	2	small	small	JJ
cord-267965-84sotgds	288	3	screens	screen	NNS
cord-267965-84sotgds	288	4	also	also	RB
cord-267965-84sotgds	288	5	facilitate	facilitate	VBP
cord-267965-84sotgds	288	6	estimation	estimation	NN
cord-267965-84sotgds	288	7	of	of	IN
cord-267965-84sotgds	288	8	the	the	DT
cord-267965-84sotgds	288	9	proportion	proportion	NN
cord-267965-84sotgds	288	10	of	of	IN
cord-267965-84sotgds	288	11	phenotypic	phenotypic	JJ
cord-267965-84sotgds	288	12	variation	variation	NN
cord-267965-84sotgds	288	13	explained	explain	VBN
cord-267965-84sotgds	288	14	by	by	IN
cord-267965-84sotgds	288	15	genetics	genetic	NNS
cord-267965-84sotgds	288	16	within	within	IN
cord-267965-84sotgds	288	17	the	the	DT
cord-267965-84sotgds	288	18	test	test	NN
cord-267965-84sotgds	288	19	population	population	NN
cord-267965-84sotgds	288	20	(	(	-LRB-
cord-267965-84sotgds	288	21	heritability	heritability	NNP
cord-267965-84sotgds	288	22	)	)	-RRB-
cord-267965-84sotgds	288	23	,	,	,
cord-267965-84sotgds	288	24	identification	identification	NN
cord-267965-84sotgds	288	25	of	of	IN
cord-267965-84sotgds	288	26	potential	potential	JJ
cord-267965-84sotgds	288	27	confounding	confounding	JJ
cord-267965-84sotgds	288	28	factors	factor	NNS
cord-267965-84sotgds	288	29	(	(	-LRB-
cord-267965-84sotgds	288	30	e.g.	e.g.	RB
cord-267965-84sotgds	288	31	,	,	,
cord-267965-84sotgds	288	32	mouse	mouse	NN
cord-267965-84sotgds	288	33	size	size	NN
cord-267965-84sotgds	288	34	and	and	CC
cord-267965-84sotgds	288	35	activity	activity	NN
cord-267965-84sotgds	288	36	levels	level	NNS
cord-267965-84sotgds	288	37	)	)	-RRB-
cord-267965-84sotgds	288	38	,	,	,
cord-267965-84sotgds	288	39	and	and	CC
cord-267965-84sotgds	288	40	performance	performance	NN
cord-267965-84sotgds	288	41	of	of	IN
cord-267965-84sotgds	288	42	power	power	NN
cord-267965-84sotgds	288	43	calculations	calculation	NNS
cord-267965-84sotgds	288	44	before	before	IN
cord-267965-84sotgds	288	45	embarking	embark	VBG
cord-267965-84sotgds	288	46	on	on	IN
cord-267965-84sotgds	288	47	a	a	DT
cord-267965-84sotgds	288	48	large	large	JJ
cord-267965-84sotgds	288	49	-	-	HYPH
cord-267965-84sotgds	288	50	scale	scale	NN
cord-267965-84sotgds	288	51	screen	screen	NN
cord-267965-84sotgds	288	52	.	.	.
cord-267965-84sotgds	289	1	In	in	IN
cord-267965-84sotgds	289	2	contrast	contrast	NN
cord-267965-84sotgds	289	3	to	to	IN
cord-267965-84sotgds	289	4	conducting	conduct	VBG
cord-267965-84sotgds	289	5	the	the	DT
cord-267965-84sotgds	289	6	initial	initial	JJ
cord-267965-84sotgds	289	7	screen	screen	NN
cord-267965-84sotgds	289	8	in	in	IN
cord-267965-84sotgds	289	9	the	the	DT
cord-267965-84sotgds	289	10	CC	CC	NNP
cord-267965-84sotgds	289	11	founders	founder	NNS
cord-267965-84sotgds	289	12	,	,	,
cord-267965-84sotgds	289	13	CC	cc	NN
cord-267965-84sotgds	289	14	strains	strain	NNS
cord-267965-84sotgds	289	15	exhibit	exhibit	VBP
cord-267965-84sotgds	289	16	more	more	JJR
cord-267965-84sotgds	289	17	phenotypic	phenotypic	JJ
cord-267965-84sotgds	289	18	diversity	diversity	NN
cord-267965-84sotgds	289	19	due	due	JJ
cord-267965-84sotgds	289	20	to	to	IN
cord-267965-84sotgds	289	21	re	re	NN
cord-267965-84sotgds	289	22	-	-	NN
cord-267965-84sotgds	289	23	assortment	assortment	JJ
cord-267965-84sotgds	289	24	of	of	IN
cord-267965-84sotgds	289	25	allelic	allelic	JJ
cord-267965-84sotgds	289	26	variants	variant	NNS
cord-267965-84sotgds	289	27	throughout	throughout	IN
cord-267965-84sotgds	289	28	the	the	DT
cord-267965-84sotgds	289	29	genome	genome	NN
cord-267965-84sotgds	289	30	.	.	.
cord-267965-84sotgds	290	1	Furthermore	furthermore	RB
cord-267965-84sotgds	290	2	,	,	,
cord-267965-84sotgds	290	3	a	a	DT
cord-267965-84sotgds	290	4	specific	specific	JJ
cord-267965-84sotgds	290	5	set	set	NN
cord-267965-84sotgds	290	6	of	of	IN
cord-267965-84sotgds	290	7	CC	cc	NN
cord-267965-84sotgds	290	8	strains	strain	NNS
cord-267965-84sotgds	290	9	can	can	MD
cord-267965-84sotgds	290	10	be	be	VB
cord-267965-84sotgds	290	11	chosen	choose	VBN
cord-267965-84sotgds	290	12	to	to	TO
cord-267965-84sotgds	290	13	avoid	avoid	VB
cord-267965-84sotgds	290	14	the	the	DT
cord-267965-84sotgds	290	15	presence	presence	NN
cord-267965-84sotgds	290	16	of	of	IN
cord-267965-84sotgds	290	17	large	large	JJ
cord-267965-84sotgds	290	18	effect	effect	NN
cord-267965-84sotgds	290	19	resistance	resistance	NN
cord-267965-84sotgds	290	20	genes	gene	NNS
cord-267965-84sotgds	290	21	such	such	JJ
cord-267965-84sotgds	290	22	as	as	IN
cord-267965-84sotgds	290	23	Mx1	mx1	JJ
cord-267965-84sotgds	290	24	or	or	CC
cord-267965-84sotgds	290	25	Oas1b	oas1b	JJ
cord-267965-84sotgds	290	26	that	that	WDT
cord-267965-84sotgds	290	27	may	may	MD
cord-267965-84sotgds	290	28	dominate	dominate	VB
cord-267965-84sotgds	290	29	the	the	DT
cord-267965-84sotgds	290	30	response	response	NN
cord-267965-84sotgds	290	31	to	to	IN
cord-267965-84sotgds	290	32	some	some	DT
cord-267965-84sotgds	290	33	pathogens	pathogen	NNS
cord-267965-84sotgds	290	34	.	.	.
cord-267965-84sotgds	291	1	Likewise	likewise	RB
cord-267965-84sotgds	291	2	,	,	,
cord-267965-84sotgds	291	3	strains	strain	NNS
cord-267965-84sotgds	291	4	can	can	MD
cord-267965-84sotgds	291	5	be	be	VB
cord-267965-84sotgds	291	6	selected	select	VBN
cord-267965-84sotgds	291	7	that	that	WDT
cord-267965-84sotgds	291	8	carry	carry	VBP
cord-267965-84sotgds	291	9	specific	specific	JJ
cord-267965-84sotgds	291	10	gene	gene	NN
cord-267965-84sotgds	291	11	haplotypes	haplotype	NNS
cord-267965-84sotgds	291	12	to	to	TO
cord-267965-84sotgds	291	13	facilitate	facilitate	VB
cord-267965-84sotgds	291	14	specific	specific	JJ
cord-267965-84sotgds	291	15	assays	assay	NNS
cord-267965-84sotgds	291	16	(	(	-LRB-
cord-267965-84sotgds	291	17	e.g.	e.g.	RB
cord-267965-84sotgds	291	18	,	,	,
cord-267965-84sotgds	291	19	MHC	MHC	NNP
cord-267965-84sotgds	291	20	haplotypes	haplotype	NNS
cord-267965-84sotgds	291	21	for	for	IN
cord-267965-84sotgds	291	22	antigen	antigen	NN
cord-267965-84sotgds	291	23	-	-	HYPH
cord-267965-84sotgds	291	24	specific	specific	JJ
cord-267965-84sotgds	291	25	T	T	NNP
cord-267965-84sotgds	291	26	cell	cell	NN
cord-267965-84sotgds	291	27	analysis	analysis	NN
cord-267965-84sotgds	291	28	)	)	-RRB-
cord-267965-84sotgds	292	1	(	(	-LRB-
cord-267965-84sotgds	292	2	Graham	Graham	NNP
cord-267965-84sotgds	292	3	et	et	NNP
cord-267965-84sotgds	292	4	al	al	NNP
cord-267965-84sotgds	292	5	.	.	.
cord-267965-84sotgds	293	1	,	,	,
cord-267965-84sotgds	293	2	2015	2015	CD
cord-267965-84sotgds	294	1	(	(	-LRB-
cord-267965-84sotgds	294	2	Graham	Graham	NNP
cord-267965-84sotgds	294	3	et	et	NNP
cord-267965-84sotgds	294	4	al	al	NNP
cord-267965-84sotgds	294	5	.	.	NNP
cord-267965-84sotgds	294	6	,	,	,
cord-267965-84sotgds	294	7	,	,	,
cord-267965-84sotgds	294	8	2017	2017	CD
cord-267965-84sotgds	294	9	.	.	.
cord-267965-84sotgds	295	1	Following	follow	VBG
cord-267965-84sotgds	295	2	an	an	DT
cord-267965-84sotgds	295	3	initial	initial	JJ
cord-267965-84sotgds	295	4	screen	screen	NN
cord-267965-84sotgds	295	5	,	,	,
cord-267965-84sotgds	295	6	researchers	researcher	NNS
cord-267965-84sotgds	295	7	interested	interested	JJ
cord-267965-84sotgds	295	8	in	in	IN
cord-267965-84sotgds	295	9	developing	develop	VBG
cord-267965-84sotgds	295	10	new	new	JJ
cord-267965-84sotgds	295	11	models	model	NNS
cord-267965-84sotgds	295	12	can	can	MD
cord-267965-84sotgds	295	13	pursue	pursue	VB
cord-267965-84sotgds	295	14	the	the	DT
cord-267965-84sotgds	295	15	strains	strain	NNS
cord-267965-84sotgds	295	16	with	with	IN
cord-267965-84sotgds	295	17	the	the	DT
cord-267965-84sotgds	295	18	most	most	RBS
cord-267965-84sotgds	295	19	relevant	relevant	JJ
cord-267965-84sotgds	295	20	phenotypes	phenotype	NNS
cord-267965-84sotgds	295	21	,	,	,
cord-267965-84sotgds	295	22	while	while	IN
cord-267965-84sotgds	295	23	those	those	DT
cord-267965-84sotgds	295	24	interested	interested	JJ
cord-267965-84sotgds	295	25	in	in	IN
cord-267965-84sotgds	295	26	genetic	genetic	JJ
cord-267965-84sotgds	295	27	mapping	mapping	NN
cord-267965-84sotgds	295	28	may	may	MD
cord-267965-84sotgds	295	29	either	either	CC
cord-267965-84sotgds	295	30	perform	perform	VB
cord-267965-84sotgds	295	31	a	a	DT
cord-267965-84sotgds	295	32	more	more	RBR
cord-267965-84sotgds	295	33	extensive	extensive	JJ
cord-267965-84sotgds	295	34	population	population	NN
cord-267965-84sotgds	295	35	-	-	HYPH
cord-267965-84sotgds	295	36	wide	wide	JJ
cord-267965-84sotgds	295	37	study	study	NN
cord-267965-84sotgds	295	38	(	(	-LRB-
cord-267965-84sotgds	295	39	e.g.	e.g.	RB
cord-267965-84sotgds	295	40	,	,	,
cord-267965-84sotgds	295	41	across	across	IN
cord-267965-84sotgds	295	42	the	the	DT
cord-267965-84sotgds	295	43	entire	entire	JJ
cord-267965-84sotgds	295	44	CC	cc	NN
cord-267965-84sotgds	295	45	)	)	-RRB-
cord-267965-84sotgds	295	46	or	or	CC
cord-267965-84sotgds	295	47	conduct	conduct	VB
cord-267965-84sotgds	295	48	a	a	DT
cord-267965-84sotgds	295	49	focused	focused	JJ
cord-267965-84sotgds	295	50	analysis	analysis	NN
cord-267965-84sotgds	295	51	of	of	IN
cord-267965-84sotgds	295	52	one	one	CD
cord-267965-84sotgds	295	53	or	or	CC
cord-267965-84sotgds	295	54	more	more	JJR
cord-267965-84sotgds	295	55	strains	strain	NNS
cord-267965-84sotgds	295	56	with	with	IN
cord-267965-84sotgds	295	57	extreme	extreme	JJ
cord-267965-84sotgds	295	58	or	or	CC
cord-267965-84sotgds	295	59	novel	novel	JJ
cord-267965-84sotgds	295	60	phenotypes	phenotype	NNS
cord-267965-84sotgds	295	61	via	via	IN
cord-267965-84sotgds	295	62	classical	classical	JJ
cord-267965-84sotgds	295	63	intercrosses	intercrosse	NNS
cord-267965-84sotgds	295	64	.	.	.
cord-267965-84sotgds	296	1	Unlike	unlike	IN
cord-267965-84sotgds	296	2	CC	CC	NNP
cord-267965-84sotgds	296	3	mice	mouse	NNS
cord-267965-84sotgds	296	4	,	,	,
cord-267965-84sotgds	296	5	which	which	WDT
cord-267965-84sotgds	296	6	are	be	VBP
cord-267965-84sotgds	296	7	fully	fully	RB
cord-267965-84sotgds	296	8	inbred	inbred	JJ
cord-267965-84sotgds	296	9	and	and	CC
cord-267965-84sotgds	296	10	genotyped	genotype	VBN
cord-267965-84sotgds	296	11	,	,	,
cord-267965-84sotgds	296	12	each	each	DT
cord-267965-84sotgds	296	13	mouse	mouse	NN
cord-267965-84sotgds	296	14	in	in	IN
cord-267965-84sotgds	296	15	an	an	DT
cord-267965-84sotgds	296	16	F2	f2	NN
cord-267965-84sotgds	296	17	or	or	CC
cord-267965-84sotgds	296	18	other	other	JJ
cord-267965-84sotgds	296	19	intercross	intercross	NNP
cord-267965-84sotgds	296	20	mapping	map	VBG
cord-267965-84sotgds	296	21	population	population	NN
cord-267965-84sotgds	296	22	will	will	MD
cord-267965-84sotgds	296	23	need	need	VB
cord-267965-84sotgds	296	24	to	to	TO
cord-267965-84sotgds	296	25	be	be	VB
cord-267965-84sotgds	296	26	genotyped	genotype	VBN
cord-267965-84sotgds	296	27	.	.	.
cord-267965-84sotgds	297	1	In	in	IN
cord-267965-84sotgds	297	2	both	both	DT
cord-267965-84sotgds	297	3	cases	case	NNS
cord-267965-84sotgds	297	4	,	,	,
cord-267965-84sotgds	297	5	genetic	genetic	JJ
cord-267965-84sotgds	297	6	mapping	mapping	NN
cord-267965-84sotgds	297	7	should	should	MD
cord-267965-84sotgds	297	8	identify	identify	VB
cord-267965-84sotgds	297	9	a	a	DT
cord-267965-84sotgds	297	10	subset	subset	NN
cord-267965-84sotgds	297	11	of	of	IN
cord-267965-84sotgds	297	12	the	the	DT
cord-267965-84sotgds	297	13	variants	variant	NNS
cord-267965-84sotgds	297	14	impacting	impact	VBG
cord-267965-84sotgds	297	15	the	the	DT
cord-267965-84sotgds	297	16	phenotype	phenotype	NN
cord-267965-84sotgds	297	17	of	of	IN
cord-267965-84sotgds	297	18	interest	interest	NN
cord-267965-84sotgds	297	19	(	(	-LRB-
cord-267965-84sotgds	297	20	e.g.	e.g.	RB
cord-267965-84sotgds	297	21	,	,	,
cord-267965-84sotgds	297	22	disease	disease	NN
cord-267965-84sotgds	297	23	)	)	-RRB-
cord-267965-84sotgds	297	24	.	.	.
cord-267965-84sotgds	298	1	While	while	IN
cord-267965-84sotgds	298	2	an	an	DT
cord-267965-84sotgds	298	3	in	in	IN
cord-267965-84sotgds	298	4	-	-	HYPH
cord-267965-84sotgds	298	5	depth	depth	NN
cord-267965-84sotgds	298	6	discussion	discussion	NN
cord-267965-84sotgds	298	7	of	of	IN
cord-267965-84sotgds	298	8	mapping	mapping	NN
cord-267965-84sotgds	298	9	methods	method	NNS
cord-267965-84sotgds	298	10	is	be	VBZ
cord-267965-84sotgds	298	11	beyond	beyond	IN
cord-267965-84sotgds	298	12	the	the	DT
cord-267965-84sotgds	298	13	scope	scope	NN
cord-267965-84sotgds	298	14	of	of	IN
cord-267965-84sotgds	298	15	this	this	DT
cord-267965-84sotgds	298	16	review	review	NN
cord-267965-84sotgds	298	17	,	,	,
cord-267965-84sotgds	298	18	several	several	JJ
cord-267965-84sotgds	298	19	robust	robust	JJ
cord-267965-84sotgds	298	20	mapping	mapping	NN
cord-267965-84sotgds	298	21	strategies	strategy	NNS
cord-267965-84sotgds	298	22	have	have	VBP
cord-267965-84sotgds	298	23	been	be	VBN
cord-267965-84sotgds	298	24	successfully	successfully	RB
cord-267965-84sotgds	298	25	applied	apply	VBN
cord-267965-84sotgds	298	26	to	to	IN
cord-267965-84sotgds	298	27	the	the	DT
cord-267965-84sotgds	298	28	CC	cc	NN
cord-267965-84sotgds	298	29	,	,	,
cord-267965-84sotgds	298	30	including	include	VBG
cord-267965-84sotgds	298	31	DOQTL	DOQTL	NNP
cord-267965-84sotgds	298	32	,	,	,
cord-267965-84sotgds	298	33	BAGPIPE	bagpipe	NN
cord-267965-84sotgds	298	34	,	,	,
cord-267965-84sotgds	298	35	and	and	CC
cord-267965-84sotgds	298	36	R	r	NN
cord-267965-84sotgds	298	37	/	/	SYM
cord-267965-84sotgds	298	38	qtl	qtl	NN
cord-267965-84sotgds	299	1	(	(	-LRB-
cord-267965-84sotgds	299	2	Arends	Arends	NNP
cord-267965-84sotgds	299	3	et	et	NNP
cord-267965-84sotgds	299	4	al	al	NNP
cord-267965-84sotgds	299	5	.	.	NNP
cord-267965-84sotgds	299	6	,	,	,
cord-267965-84sotgds	299	7	2010	2010	CD
cord-267965-84sotgds	299	8	;	;	:
cord-267965-84sotgds	299	9	Gatti	Gatti	NNP
cord-267965-84sotgds	299	10	et	et	NNP
cord-267965-84sotgds	299	11	al	al	NNP
cord-267965-84sotgds	299	12	.	.	NNP
cord-267965-84sotgds	299	13	,	,	,
cord-267965-84sotgds	299	14	2014	2014	CD
cord-267965-84sotgds	299	15	;	;	:
cord-267965-84sotgds	299	16	Valdar	Valdar	NNP
cord-267965-84sotgds	299	17	et	et	NNP
cord-267965-84sotgds	299	18	al	al	NNP
cord-267965-84sotgds	299	19	.	.	NNP
cord-267965-84sotgds	299	20	,	,	,
cord-267965-84sotgds	299	21	2009	2009	CD
cord-267965-84sotgds	299	22	)	)	-RRB-
cord-267965-84sotgds	299	23	.	.	.
cord-267965-84sotgds	300	1	Once	once	IN
cord-267965-84sotgds	300	2	QTLs	qtl	NNS
cord-267965-84sotgds	300	3	have	have	VBP
cord-267965-84sotgds	300	4	been	be	VBN
cord-267965-84sotgds	300	5	mapped	map	VBN
cord-267965-84sotgds	300	6	,	,	,
cord-267965-84sotgds	300	7	investigators	investigator	NNS
cord-267965-84sotgds	300	8	can	can	MD
cord-267965-84sotgds	300	9	confirm	confirm	VB
cord-267965-84sotgds	300	10	the	the	DT
cord-267965-84sotgds	300	11	underlying	underlie	VBG
cord-267965-84sotgds	300	12	haplotype	haplotype	NN
cord-267965-84sotgds	300	13	effects	effect	NNS
cord-267965-84sotgds	300	14	by	by	IN
cord-267965-84sotgds	300	15	screening	screen	VBG
cord-267965-84sotgds	300	16	additional	additional	JJ
cord-267965-84sotgds	300	17	CC	cc	NN
cord-267965-84sotgds	300	18	strains	strain	NNS
cord-267965-84sotgds	300	19	with	with	IN
cord-267965-84sotgds	300	20	high	high	JJ
cord-267965-84sotgds	300	21	or	or	CC
cord-267965-84sotgds	300	22	low	low	JJ
cord-267965-84sotgds	300	23	responder	responder	NN
cord-267965-84sotgds	300	24	haplotypes	haplotype	NNS
cord-267965-84sotgds	300	25	under	under	IN
cord-267965-84sotgds	300	26	the	the	DT
cord-267965-84sotgds	300	27	QTLs	qtl	NNS
cord-267965-84sotgds	300	28	that	that	WDT
cord-267965-84sotgds	300	29	were	be	VBD
cord-267965-84sotgds	300	30	not	not	RB
cord-267965-84sotgds	300	31	included	include	VBN
cord-267965-84sotgds	300	32	in	in	IN
cord-267965-84sotgds	300	33	the	the	DT
cord-267965-84sotgds	300	34	initial	initial	JJ
cord-267965-84sotgds	300	35	screen	screen	NN
cord-267965-84sotgds	300	36	,	,	,
cord-267965-84sotgds	300	37	or	or	CC
cord-267965-84sotgds	300	38	by	by	IN
cord-267965-84sotgds	300	39	screening	screen	VBG
cord-267965-84sotgds	300	40	a	a	DT
cord-267965-84sotgds	300	41	set	set	NN
cord-267965-84sotgds	300	42	of	of	IN
cord-267965-84sotgds	300	43	mice	mouse	NNS
cord-267965-84sotgds	300	44	from	from	IN
cord-267965-84sotgds	300	45	the	the	DT
cord-267965-84sotgds	300	46	related	related	JJ
cord-267965-84sotgds	300	47	DO	DO	NNP
cord-267965-84sotgds	300	48	population	population	NN
cord-267965-84sotgds	300	49	.	.	.
cord-267965-84sotgds	301	1	While	while	IN
cord-267965-84sotgds	301	2	not	not	RB
cord-267965-84sotgds	301	3	essential	essential	JJ
cord-267965-84sotgds	301	4	,	,	,
cord-267965-84sotgds	301	5	this	this	DT
cord-267965-84sotgds	301	6	step	step	NN
cord-267965-84sotgds	301	7	confirms	confirm	VBZ
cord-267965-84sotgds	301	8	the	the	DT
cord-267965-84sotgds	301	9	initial	initial	JJ
cord-267965-84sotgds	301	10	mapping	mapping	NN
cord-267965-84sotgds	301	11	studies	study	NNS
cord-267965-84sotgds	301	12	and	and	CC
cord-267965-84sotgds	301	13	provides	provide	VBZ
cord-267965-84sotgds	301	14	confidence	confidence	NN
cord-267965-84sotgds	301	15	in	in	IN
cord-267965-84sotgds	301	16	the	the	DT
cord-267965-84sotgds	301	17	QTL	QTL	NNP
cord-267965-84sotgds	301	18	effects	effect	NNS
cord-267965-84sotgds	301	19	prior	prior	RB
cord-267965-84sotgds	301	20	to	to	IN
cord-267965-84sotgds	301	21	embarking	embark	VBG
cord-267965-84sotgds	301	22	on	on	IN
cord-267965-84sotgds	301	23	candidate	candidate	NN
cord-267965-84sotgds	301	24	gene	gene	NN
cord-267965-84sotgds	301	25	investigation	investigation	NN
cord-267965-84sotgds	301	26	.	.	.
cord-267965-84sotgds	302	1	The	the	DT
cord-267965-84sotgds	302	2	identification	identification	NN
cord-267965-84sotgds	302	3	and	and	CC
cord-267965-84sotgds	302	4	validation	validation	NN
cord-267965-84sotgds	302	5	of	of	IN
cord-267965-84sotgds	302	6	candidate	candidate	NN
cord-267965-84sotgds	302	7	genes	gene	NNS
cord-267965-84sotgds	302	8	can	can	MD
cord-267965-84sotgds	302	9	be	be	VB
cord-267965-84sotgds	302	10	a	a	DT
cord-267965-84sotgds	302	11	challenging	challenging	JJ
cord-267965-84sotgds	302	12	and	and	CC
cord-267965-84sotgds	302	13	intensive	intensive	JJ
cord-267965-84sotgds	302	14	process	process	NN
cord-267965-84sotgds	302	15	.	.	.
cord-267965-84sotgds	303	1	QTLs	qtl	NNS
cord-267965-84sotgds	303	2	are	be	VBP
cord-267965-84sotgds	303	3	often	often	RB
cord-267965-84sotgds	303	4	large	large	JJ
cord-267965-84sotgds	303	5	,	,	,
cord-267965-84sotgds	303	6	containing	contain	VBG
cord-267965-84sotgds	303	7	tens	ten	NNS
cord-267965-84sotgds	303	8	to	to	IN
cord-267965-84sotgds	303	9	hundreds	hundred	NNS
cord-267965-84sotgds	303	10	of	of	IN
cord-267965-84sotgds	303	11	genes	gene	NNS
cord-267965-84sotgds	303	12	.	.	.
cord-267965-84sotgds	304	1	In	in	IN
cord-267965-84sotgds	304	2	contrast	contrast	NN
cord-267965-84sotgds	304	3	to	to	IN
cord-267965-84sotgds	304	4	mapping	mapping	NN
cord-267965-84sotgds	304	5	in	in	IN
cord-267965-84sotgds	304	6	biparental	biparental	JJ
cord-267965-84sotgds	304	7	GRPs	grp	NNS
cord-267965-84sotgds	304	8	or	or	CC
cord-267965-84sotgds	304	9	intercross	intercross	NNP
cord-267965-84sotgds	304	10	populations	population	NNS
cord-267965-84sotgds	304	11	,	,	,
cord-267965-84sotgds	304	12	where	where	WRB
cord-267965-84sotgds	304	13	there	there	EX
cord-267965-84sotgds	304	14	are	be	VBP
cord-267965-84sotgds	304	15	only	only	RB
cord-267965-84sotgds	304	16	two	two	CD
cord-267965-84sotgds	304	17	haplotypes	haplotype	NNS
cord-267965-84sotgds	304	18	and	and	CC
cord-267965-84sotgds	304	19	every	every	DT
cord-267965-84sotgds	304	20	variant	variant	NN
cord-267965-84sotgds	304	21	is	be	VBZ
cord-267965-84sotgds	304	22	a	a	DT
cord-267965-84sotgds	304	23	putative	putative	JJ
cord-267965-84sotgds	304	24	candidate	candidate	NN
cord-267965-84sotgds	304	25	,	,	,
cord-267965-84sotgds	304	26	in	in	IN
cord-267965-84sotgds	304	27	the	the	DT
cord-267965-84sotgds	304	28	CC	CC	NNP
cord-267965-84sotgds	304	29	,	,	,
cord-267965-84sotgds	304	30	merge	merge	VB
cord-267965-84sotgds	304	31	analysis	analysis	NN
cord-267965-84sotgds	304	32	(	(	-LRB-
cord-267965-84sotgds	305	1	Yalcin	Yalcin	NNP
cord-267965-84sotgds	305	2	et	et	NNP
cord-267965-84sotgds	305	3	al	al	NNP
cord-267965-84sotgds	305	4	.	.	NNP
cord-267965-84sotgds	305	5	,	,	,
cord-267965-84sotgds	305	6	2005	2005	CD
cord-267965-84sotgds	305	7	)	)	-RRB-
cord-267965-84sotgds	305	8	can	can	MD
cord-267965-84sotgds	305	9	be	be	VB
cord-267965-84sotgds	305	10	used	use	VBN
cord-267965-84sotgds	305	11	to	to	TO
cord-267965-84sotgds	305	12	narrow	narrow	VB
cord-267965-84sotgds	305	13	candidates	candidate	NNS
cord-267965-84sotgds	305	14	based	base	VBN
cord-267965-84sotgds	305	15	on	on	IN
cord-267965-84sotgds	305	16	how	how	WRB
cord-267965-84sotgds	305	17	the	the	DT
cord-267965-84sotgds	305	18	pattern	pattern	NN
cord-267965-84sotgds	305	19	of	of	IN
cord-267965-84sotgds	305	20	variants	variant	NNS
cord-267965-84sotgds	305	21	(	(	-LRB-
cord-267965-84sotgds	305	22	e.g.	e.g.	RB
cord-267965-84sotgds	305	23	,	,	,
cord-267965-84sotgds	305	24	SNPs	SNPs	NNPS
cord-267965-84sotgds	305	25	or	or	CC
cord-267965-84sotgds	305	26	indels	indel	NNS
cord-267965-84sotgds	305	27	)	)	-RRB-
cord-267965-84sotgds	305	28	for	for	IN
cord-267965-84sotgds	305	29	each	each	DT
cord-267965-84sotgds	305	30	founder	founder	NN
cord-267965-84sotgds	305	31	matches	match	VBZ
cord-267965-84sotgds	305	32	the	the	DT
cord-267965-84sotgds	305	33	distribution	distribution	NN
cord-267965-84sotgds	305	34	of	of	IN
cord-267965-84sotgds	305	35	phenotypic	phenotypic	JJ
cord-267965-84sotgds	305	36	responses	response	NNS
cord-267965-84sotgds	305	37	associated	associate	VBN
cord-267965-84sotgds	305	38	with	with	IN
cord-267965-84sotgds	305	39	each	each	DT
cord-267965-84sotgds	305	40	founder	founder	NN
cord-267965-84sotgds	305	41	haplotype	haplotype	NN
cord-267965-84sotgds	305	42	.	.	.
cord-267965-84sotgds	306	1	As	as	IN
cord-267965-84sotgds	306	2	described	describe	VBN
cord-267965-84sotgds	306	3	above	above	RB
cord-267965-84sotgds	306	4	,	,	,
cord-267965-84sotgds	306	5	merge	merge	VB
cord-267965-84sotgds	306	6	analysis	analysis	NN
cord-267965-84sotgds	306	7	has	have	VBZ
cord-267965-84sotgds	306	8	been	be	VBN
cord-267965-84sotgds	306	9	a	a	DT
cord-267965-84sotgds	306	10	useful	useful	JJ
cord-267965-84sotgds	306	11	tool	tool	NN
cord-267965-84sotgds	306	12	in	in	IN
cord-267965-84sotgds	306	13	the	the	DT
cord-267965-84sotgds	306	14	CC	cc	NN
cord-267965-84sotgds	306	15	;	;	:
cord-267965-84sotgds	306	16	however	however	RB
cord-267965-84sotgds	306	17	,	,	,
cord-267965-84sotgds	306	18	a	a	DT
cord-267965-84sotgds	306	19	drawback	drawback	NN
cord-267965-84sotgds	306	20	of	of	IN
cord-267965-84sotgds	306	21	merge	merge	NN
cord-267965-84sotgds	306	22	analysis	analysis	NN
cord-267965-84sotgds	306	23	is	be	VBZ
cord-267965-84sotgds	306	24	that	that	IN
cord-267965-84sotgds	306	25	it	-PRON-	PRP
cord-267965-84sotgds	306	26	assumes	assume	VBZ
cord-267965-84sotgds	306	27	a	a	DT
cord-267965-84sotgds	306	28	single	single	JJ
cord-267965-84sotgds	306	29	SNP	SNP	NNP
cord-267965-84sotgds	306	30	variant	variant	NN
cord-267965-84sotgds	306	31	driving	drive	VBG
cord-267965-84sotgds	306	32	the	the	DT
cord-267965-84sotgds	306	33	locus	locus	NN
cord-267965-84sotgds	306	34	.	.	.
cord-267965-84sotgds	307	1	In	in	IN
cord-267965-84sotgds	307	2	multi	multi	JJ
cord-267965-84sotgds	307	3	-	-	JJ
cord-267965-84sotgds	307	4	parental	parental	JJ
cord-267965-84sotgds	307	5	populations	population	NNS
cord-267965-84sotgds	307	6	,	,	,
cord-267965-84sotgds	307	7	different	different	JJ
cord-267965-84sotgds	307	8	SNPs	snp	NNS
cord-267965-84sotgds	307	9	or	or	CC
cord-267965-84sotgds	307	10	other	other	JJ
cord-267965-84sotgds	307	11	mutations	mutation	NNS
cord-267965-84sotgds	307	12	within	within	IN
cord-267965-84sotgds	307	13	the	the	DT
cord-267965-84sotgds	307	14	same	same	JJ
cord-267965-84sotgds	307	15	gene	gene	NN
cord-267965-84sotgds	307	16	may	may	MD
cord-267965-84sotgds	307	17	phenocopy	phenocopy	VB
cord-267965-84sotgds	307	18	one	one	NN
cord-267965-84sotgds	307	19	another	another	DT
cord-267965-84sotgds	307	20	(	(	-LRB-
cord-267965-84sotgds	307	21	e.g.	e.g.	RB
cord-267965-84sotgds	307	22	,	,	,
cord-267965-84sotgds	307	23	different	different	JJ
cord-267965-84sotgds	307	24	Mx1	mx1	JJ
cord-267965-84sotgds	307	25	null	null	JJ
cord-267965-84sotgds	307	26	alleles	allele	NNS
cord-267965-84sotgds	307	27	;	;	:
cord-267965-84sotgds	307	28	Ferris	Ferris	NNP
cord-267965-84sotgds	307	29	et	et	NNP
cord-267965-84sotgds	307	30	al	al	NNP
cord-267965-84sotgds	307	31	.	.	NNP
cord-267965-84sotgds	307	32	,	,	,
cord-267965-84sotgds	307	33	2013	2013	CD
cord-267965-84sotgds	307	34	)	)	-RRB-
cord-267965-84sotgds	307	35	.	.	.
cord-267965-84sotgds	308	1	Furthermore	furthermore	RB
cord-267965-84sotgds	308	2	,	,	,
cord-267965-84sotgds	308	3	other	other	JJ
cord-267965-84sotgds	308	4	genetic	genetic	JJ
cord-267965-84sotgds	308	5	variants	variant	NNS
cord-267965-84sotgds	308	6	(	(	-LRB-
cord-267965-84sotgds	308	7	e.g.	e.g.	RB
cord-267965-84sotgds	308	8	,	,	,
cord-267965-84sotgds	308	9	copy	copy	NN
cord-267965-84sotgds	308	10	number	number	NN
cord-267965-84sotgds	308	11	variants	variant	NNS
cord-267965-84sotgds	308	12	and	and	CC
cord-267965-84sotgds	308	13	transposable	transposable	JJ
cord-267965-84sotgds	308	14	elements	element	NNS
cord-267965-84sotgds	308	15	)	)	-RRB-
cord-267965-84sotgds	308	16	are	be	VBP
cord-267965-84sotgds	308	17	often	often	RB
cord-267965-84sotgds	308	18	missed	miss	VBN
cord-267965-84sotgds	308	19	by	by	IN
cord-267965-84sotgds	308	20	traditional	traditional	JJ
cord-267965-84sotgds	308	21	merge	merge	NN
cord-267965-84sotgds	308	22	databases	database	NNS
cord-267965-84sotgds	308	23	.	.	.
cord-267965-84sotgds	309	1	Other	other	JJ
cord-267965-84sotgds	309	2	in	in	IN
cord-267965-84sotgds	309	3	silico	silico	NN
cord-267965-84sotgds	309	4	tools	tool	NNS
cord-267965-84sotgds	309	5	,	,	,
cord-267965-84sotgds	309	6	including	include	VBG
cord-267965-84sotgds	309	7	baseline	baseline	JJ
cord-267965-84sotgds	309	8	tissue	tissue	NN
cord-267965-84sotgds	309	9	and/or	and/or	CC
cord-267965-84sotgds	309	10	haplotype	haplotype	NN
cord-267965-84sotgds	309	11	-	-	HYPH
cord-267965-84sotgds	309	12	specific	specific	JJ
cord-267965-84sotgds	309	13	gene	gene	NN
cord-267965-84sotgds	309	14	expression	expression	NN
cord-267965-84sotgds	309	15	(	(	-LRB-
cord-267965-84sotgds	309	16	e.g.	e.g.	RB
cord-267965-84sotgds	309	17	,	,	,
cord-267965-84sotgds	309	18	ImmGen	ImmGen	NNP
cord-267965-84sotgds	309	19	and	and	CC
cord-267965-84sotgds	309	20	GECCO	GECCO	NNP
cord-267965-84sotgds	309	21	)	)	-RRB-
cord-267965-84sotgds	310	1	(	(	-LRB-
cord-267965-84sotgds	310	2	Shay	Shay	NNP
cord-267965-84sotgds	310	3	and	and	CC
cord-267965-84sotgds	310	4	Kang	Kang	NNP
cord-267965-84sotgds	310	5	,	,	,
cord-267965-84sotgds	310	6	2013	2013	CD
cord-267965-84sotgds	310	7	;	;	:
cord-267965-84sotgds	310	8	http://csbio.unc.edu/gecco	http://csbio.unc.edu/gecco	ADD
cord-267965-84sotgds	310	9	)	)	-RRB-
cord-267965-84sotgds	310	10	and	and	CC
cord-267965-84sotgds	310	11	protein	protein	VB
cord-267965-84sotgds	310	12	functional	functional	JJ
cord-267965-84sotgds	310	13	consequence	consequence	NN
cord-267965-84sotgds	310	14	prediction	prediction	NN
cord-267965-84sotgds	310	15	(	(	-LRB-
cord-267965-84sotgds	310	16	e.g.	e.g.	RB
cord-267965-84sotgds	310	17	,	,	,
cord-267965-84sotgds	310	18	SIFT	sift	VB
cord-267965-84sotgds	310	19	;	;	:
cord-267965-84sotgds	310	20	Sim	Sim	NNP
cord-267965-84sotgds	310	21	et	et	FW
cord-267965-84sotgds	310	22	al	al	NNP
cord-267965-84sotgds	310	23	.	.	NNP
cord-267965-84sotgds	310	24	,	,	,
cord-267965-84sotgds	310	25	2012	2012	CD
cord-267965-84sotgds	310	26	)	)	-RRB-
cord-267965-84sotgds	310	27	,	,	,
cord-267965-84sotgds	310	28	can	can	MD
cord-267965-84sotgds	310	29	help	help	VB
cord-267965-84sotgds	310	30	narrow	narrow	JJ
cord-267965-84sotgds	310	31	candidates	candidate	NNS
cord-267965-84sotgds	310	32	to	to	IN
cord-267965-84sotgds	310	33	a	a	DT
cord-267965-84sotgds	310	34	single	single	JJ
cord-267965-84sotgds	310	35	high	high	JJ
cord-267965-84sotgds	310	36	-	-	HYPH
cord-267965-84sotgds	310	37	priority	priority	NN
cord-267965-84sotgds	310	38	candidate	candidate	NN
cord-267965-84sotgds	310	39	gene	gene	NN
cord-267965-84sotgds	310	40	or	or	CC
cord-267965-84sotgds	310	41	small	small	JJ
cord-267965-84sotgds	310	42	set	set	NN
cord-267965-84sotgds	310	43	of	of	IN
cord-267965-84sotgds	310	44	candidates	candidate	NNS
cord-267965-84sotgds	310	45	(	(	-LRB-
cord-267965-84sotgds	310	46	Ferris	Ferris	NNP
cord-267965-84sotgds	310	47	et	et	NNP
cord-267965-84sotgds	310	48	al	al	NNP
cord-267965-84sotgds	310	49	.	.	NNP
cord-267965-84sotgds	310	50	,	,	,
cord-267965-84sotgds	310	51	2013	2013	CD
cord-267965-84sotgds	310	52	;	;	:
cord-267965-84sotgds	311	1	Gralinski	Gralinski	NNP
cord-267965-84sotgds	311	2	et	et	FW
cord-267965-84sotgds	311	3	al	al	NNP
cord-267965-84sotgds	311	4	.	.	NNP
cord-267965-84sotgds	311	5	,	,	,
cord-267965-84sotgds	311	6	2015	2015	CD
cord-267965-84sotgds	311	7	)	)	-RRB-
cord-267965-84sotgds	311	8	.	.	.
cord-267965-84sotgds	312	1	Alternatively	alternatively	RB
cord-267965-84sotgds	312	2	,	,	,
cord-267965-84sotgds	312	3	if	if	IN
cord-267965-84sotgds	312	4	causal	causal	JJ
cord-267965-84sotgds	312	5	variants	variant	NNS
cord-267965-84sotgds	312	6	are	be	VBP
cord-267965-84sotgds	312	7	suspected	suspect	VBN
cord-267965-84sotgds	312	8	of	of	IN
cord-267965-84sotgds	312	9	altering	alter	VBG
cord-267965-84sotgds	312	10	transcript	transcript	NN
cord-267965-84sotgds	312	11	levels	level	NNS
cord-267965-84sotgds	312	12	,	,	,
cord-267965-84sotgds	312	13	de	de	FW
cord-267965-84sotgds	312	14	novo	novo	NNP
cord-267965-84sotgds	312	15	gene	gene	NNP
cord-267965-84sotgds	312	16	expression	expression	NN
cord-267965-84sotgds	312	17	analysis	analysis	NN
cord-267965-84sotgds	312	18	can	can	MD
cord-267965-84sotgds	312	19	be	be	VB
cord-267965-84sotgds	312	20	used	use	VBN
cord-267965-84sotgds	312	21	to	to	TO
cord-267965-84sotgds	312	22	further	further	RB
cord-267965-84sotgds	312	23	refine	refine	VB
cord-267965-84sotgds	312	24	candidate	candidate	NN
cord-267965-84sotgds	312	25	genes	gene	NNS
cord-267965-84sotgds	312	26	under	under	IN
cord-267965-84sotgds	312	27	the	the	DT
cord-267965-84sotgds	312	28	locus	locus	NN
cord-267965-84sotgds	312	29	.	.	.
cord-267965-84sotgds	313	1	Following	follow	VBG
cord-267965-84sotgds	313	2	candidate	candidate	NN
cord-267965-84sotgds	313	3	gene	gene	NN
cord-267965-84sotgds	313	4	identification	identification	NN
cord-267965-84sotgds	313	5	,	,	,
cord-267965-84sotgds	313	6	there	there	EX
cord-267965-84sotgds	313	7	are	be	VBP
cord-267965-84sotgds	313	8	several	several	JJ
cord-267965-84sotgds	313	9	options	option	NNS
cord-267965-84sotgds	313	10	for	for	IN
cord-267965-84sotgds	313	11	testing	testing	NN
cord-267965-84sotgds	313	12	whether	whether	IN
cord-267965-84sotgds	313	13	the	the	DT
cord-267965-84sotgds	313	14	candidate	candidate	NN
cord-267965-84sotgds	313	15	is	be	VBZ
cord-267965-84sotgds	313	16	actually	actually	RB
cord-267965-84sotgds	313	17	causal	causal	JJ
cord-267965-84sotgds	313	18	.	.	.
cord-267965-84sotgds	314	1	When	when	WRB
cord-267965-84sotgds	314	2	the	the	DT
cord-267965-84sotgds	314	3	phenotype	phenotype	NN
cord-267965-84sotgds	314	4	is	be	VBZ
cord-267965-84sotgds	314	5	driven	drive	VBN
cord-267965-84sotgds	314	6	by	by	IN
cord-267965-84sotgds	314	7	an	an	DT
cord-267965-84sotgds	314	8	individual	individual	JJ
cord-267965-84sotgds	314	9	cellular	cellular	JJ
cord-267965-84sotgds	314	10	factor	factor	NN
cord-267965-84sotgds	314	11	,	,	,
cord-267965-84sotgds	314	12	such	such	JJ
cord-267965-84sotgds	314	13	as	as	IN
cord-267965-84sotgds	314	14	an	an	DT
cord-267965-84sotgds	314	15	antiviral	antiviral	JJ
cord-267965-84sotgds	314	16	molecule	molecule	NN
cord-267965-84sotgds	314	17	or	or	CC
cord-267965-84sotgds	314	18	receptor	receptor	NN
cord-267965-84sotgds	314	19	,	,	,
cord-267965-84sotgds	314	20	gene	gene	NN
cord-267965-84sotgds	314	21	function	function	NN
cord-267965-84sotgds	314	22	can	can	MD
cord-267965-84sotgds	314	23	be	be	VB
cord-267965-84sotgds	314	24	validated	validate	VBN
cord-267965-84sotgds	314	25	in	in	IN
cord-267965-84sotgds	314	26	vitro	vitro	FW
cord-267965-84sotgds	314	27	using	use	VBG
cord-267965-84sotgds	314	28	techniques	technique	NNS
cord-267965-84sotgds	314	29	such	such	JJ
cord-267965-84sotgds	314	30	as	as	IN
cord-267965-84sotgds	314	31	CRISPR	CRISPR	NNP
cord-267965-84sotgds	314	32	or	or	CC
cord-267965-84sotgds	314	33	ectopic	ectopic	JJ
cord-267965-84sotgds	314	34	expression	expression	NN
cord-267965-84sotgds	314	35	of	of	IN
cord-267965-84sotgds	314	36	different	different	JJ
cord-267965-84sotgds	314	37	variants	variant	NNS
cord-267965-84sotgds	314	38	.	.	.
cord-267965-84sotgds	315	1	When	when	WRB
cord-267965-84sotgds	315	2	the	the	DT
cord-267965-84sotgds	315	3	phenotype	phenotype	NN
cord-267965-84sotgds	315	4	has	have	VBZ
cord-267965-84sotgds	315	5	a	a	DT
cord-267965-84sotgds	315	6	more	more	RBR
cord-267965-84sotgds	315	7	systemic	systemic	JJ
cord-267965-84sotgds	315	8	cause	cause	NN
cord-267965-84sotgds	315	9	,	,	,
cord-267965-84sotgds	315	10	in	in	IN
cord-267965-84sotgds	315	11	vivo	vivo	NN
cord-267965-84sotgds	315	12	validation	validation	NN
cord-267965-84sotgds	315	13	is	be	VBZ
cord-267965-84sotgds	315	14	generally	generally	RB
cord-267965-84sotgds	315	15	necessary	necessary	JJ
cord-267965-84sotgds	315	16	.	.	.
cord-267965-84sotgds	316	1	This	this	DT
cord-267965-84sotgds	316	2	can	can	MD
cord-267965-84sotgds	316	3	be	be	VB
cord-267965-84sotgds	316	4	facilitated	facilitate	VBN
cord-267965-84sotgds	316	5	by	by	IN
cord-267965-84sotgds	316	6	the	the	DT
cord-267965-84sotgds	316	7	wide	wide	JJ
cord-267965-84sotgds	316	8	availability	availability	NN
cord-267965-84sotgds	316	9	of	of	IN
cord-267965-84sotgds	316	10	knockout	knockout	NN
cord-267965-84sotgds	316	11	mouse	mouse	NN
cord-267965-84sotgds	316	12	lines	line	NNS
cord-267965-84sotgds	316	13	(	(	-LRB-
cord-267965-84sotgds	316	14	Gralinski	Gralinski	NNP
cord-267965-84sotgds	316	15	et	et	FW
cord-267965-84sotgds	316	16	al	al	NNP
cord-267965-84sotgds	316	17	.	.	NNP
cord-267965-84sotgds	316	18	,	,	,
cord-267965-84sotgds	316	19	2015	2015	CD
cord-267965-84sotgds	317	1	(	(	-LRB-
cord-267965-84sotgds	317	2	Gralinski	Gralinski	NNP
cord-267965-84sotgds	317	3	et	et	FW
cord-267965-84sotgds	317	4	al	al	NNP
cord-267965-84sotgds	317	5	.	.	NNP
cord-267965-84sotgds	317	6	,	,	,
cord-267965-84sotgds	317	7	,	,	,
cord-267965-84sotgds	317	8	2017	2017	CD
cord-267965-84sotgds	317	9	.	.	.
cord-267965-84sotgds	318	1	However	however	RB
cord-267965-84sotgds	318	2	,	,	,
cord-267965-84sotgds	318	3	in	in	IN
cord-267965-84sotgds	318	4	vivo	vivo	NN
cord-267965-84sotgds	318	5	validation	validation	NN
cord-267965-84sotgds	318	6	studies	study	NNS
cord-267965-84sotgds	318	7	should	should	MD
cord-267965-84sotgds	318	8	take	take	VB
cord-267965-84sotgds	318	9	into	into	IN
cord-267965-84sotgds	318	10	account	account	NN
cord-267965-84sotgds	318	11	factors	factor	NNS
cord-267965-84sotgds	318	12	such	such	JJ
cord-267965-84sotgds	318	13	as	as	IN
cord-267965-84sotgds	318	14	genetic	genetic	JJ
cord-267965-84sotgds	318	15	background	background	NN
cord-267965-84sotgds	318	16	of	of	IN
cord-267965-84sotgds	318	17	the	the	DT
cord-267965-84sotgds	318	18	knockout	knockout	NN
cord-267965-84sotgds	318	19	,	,	,
cord-267965-84sotgds	318	20	the	the	DT
cord-267965-84sotgds	318	21	effect	effect	NN
cord-267965-84sotgds	318	22	of	of	IN
cord-267965-84sotgds	318	23	the	the	DT
cord-267965-84sotgds	318	24	variant	variant	NN
cord-267965-84sotgds	318	25	,	,	,
cord-267965-84sotgds	318	26	and	and	CC
cord-267965-84sotgds	318	27	the	the	DT
cord-267965-84sotgds	318	28	distribution	distribution	NN
cord-267965-84sotgds	318	29	of	of	IN
cord-267965-84sotgds	318	30	haplotypes	haplotype	NNS
cord-267965-84sotgds	318	31	(	(	-LRB-
cord-267965-84sotgds	318	32	e.g.	e.g.	RB
cord-267965-84sotgds	318	33	,	,	,
cord-267965-84sotgds	318	34	a	a	DT
cord-267965-84sotgds	318	35	knockout	knockout	NN
cord-267965-84sotgds	318	36	on	on	IN
cord-267965-84sotgds	318	37	a	a	DT
cord-267965-84sotgds	318	38	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	318	39	background	background	NN
cord-267965-84sotgds	318	40	may	may	MD
cord-267965-84sotgds	318	41	not	not	RB
cord-267965-84sotgds	318	42	provide	provide	VB
cord-267965-84sotgds	318	43	an	an	DT
cord-267965-84sotgds	318	44	interpretable	interpretable	JJ
cord-267965-84sotgds	318	45	phenotype	phenotype	NN
cord-267965-84sotgds	318	46	if	if	IN
cord-267965-84sotgds	318	47	,	,	,
cord-267965-84sotgds	318	48	in	in	IN
cord-267965-84sotgds	318	49	the	the	DT
cord-267965-84sotgds	318	50	CC	CC	NNP
cord-267965-84sotgds	318	51	,	,	,
cord-267965-84sotgds	318	52	the	the	DT
cord-267965-84sotgds	318	53	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	318	54	haplotype	haplotype	NN
cord-267965-84sotgds	318	55	is	be	VBZ
cord-267965-84sotgds	318	56	an	an	DT
cord-267965-84sotgds	318	57	extreme	extreme	JJ
cord-267965-84sotgds	318	58	response	response	NN
cord-267965-84sotgds	318	59	haplotype	haplotype	NN
cord-267965-84sotgds	318	60	,	,	,
cord-267965-84sotgds	318	61	or	or	CC
cord-267965-84sotgds	318	62	if	if	IN
cord-267965-84sotgds	318	63	the	the	DT
cord-267965-84sotgds	318	64	C57BL/6J	C57BL/6J	NNP
cord-267965-84sotgds	318	65	allele	allele	NN
cord-267965-84sotgds	318	66	is	be	VBZ
cord-267965-84sotgds	318	67	hypomorphic	hypomorphic	JJ
cord-267965-84sotgds	318	68	or	or	CC
cord-267965-84sotgds	318	69	amorphic	amorphic	JJ
cord-267965-84sotgds	318	70	)	)	-RRB-
cord-267965-84sotgds	318	71	.	.	.
cord-267965-84sotgds	319	1	More	More	JJR
cord-267965-84sotgds	319	2	recent	recent	JJ
cord-267965-84sotgds	319	3	advances	advance	NNS
cord-267965-84sotgds	319	4	in	in	IN
cord-267965-84sotgds	319	5	CRISPR	CRISPR	NNP
cord-267965-84sotgds	319	6	technology	technology	NN
cord-267965-84sotgds	319	7	open	open	VBP
cord-267965-84sotgds	319	8	up	up	RP
cord-267965-84sotgds	319	9	the	the	DT
cord-267965-84sotgds	319	10	possibility	possibility	NN
cord-267965-84sotgds	319	11	of	of	IN
cord-267965-84sotgds	319	12	knocking	knock	VBG
cord-267965-84sotgds	319	13	out	out	RP
cord-267965-84sotgds	319	14	or	or	CC
cord-267965-84sotgds	319	15	performing	perform	VBG
cord-267965-84sotgds	319	16	allele	allele	NN
cord-267965-84sotgds	319	17	swaps	swap	NNS
cord-267965-84sotgds	319	18	in	in	IN
cord-267965-84sotgds	319	19	genes	gene	NNS
cord-267965-84sotgds	319	20	directly	directly	RB
cord-267965-84sotgds	319	21	in	in	IN
cord-267965-84sotgds	319	22	CC	CC	NNP
cord-267965-84sotgds	319	23	founders	founder	NNS
cord-267965-84sotgds	319	24	or	or	CC
cord-267965-84sotgds	319	25	RI	RI	NNP
cord-267965-84sotgds	319	26	strains	strain	NNS
cord-267965-84sotgds	319	27	,	,	,
cord-267965-84sotgds	319	28	enhancing	enhance	VBG
cord-267965-84sotgds	319	29	the	the	DT
cord-267965-84sotgds	319	30	utility	utility	NN
cord-267965-84sotgds	319	31	of	of	IN
cord-267965-84sotgds	319	32	the	the	DT
cord-267965-84sotgds	319	33	CC	CC	NNP
cord-267965-84sotgds	319	34	as	as	IN
cord-267965-84sotgds	319	35	a	a	DT
cord-267965-84sotgds	319	36	resource	resource	NN
cord-267965-84sotgds	319	37	for	for	IN
cord-267965-84sotgds	319	38	both	both	DT
cord-267965-84sotgds	319	39	identifying	identify	VBG
cord-267965-84sotgds	319	40	and	and	CC
cord-267965-84sotgds	319	41	studying	study	VBG
cord-267965-84sotgds	319	42	polymorphic	polymorphic	JJ
cord-267965-84sotgds	319	43	genes	gene	NNS
cord-267965-84sotgds	319	44	affecting	affect	VBG
cord-267965-84sotgds	319	45	pathogen	pathogen	NN
cord-267965-84sotgds	319	46	susceptibility	susceptibility	NN
cord-267965-84sotgds	319	47	or	or	CC
cord-267965-84sotgds	319	48	other	other	JJ
cord-267965-84sotgds	319	49	phenotypes	phenotype	NNS
cord-267965-84sotgds	319	50	of	of	IN
cord-267965-84sotgds	319	51	interest	interest	NN
cord-267965-84sotgds	319	52	.	.	.
cord-267965-84sotgds	320	1	In	in	IN
cord-267965-84sotgds	320	2	less	less	JJR
cord-267965-84sotgds	320	3	than	than	IN
cord-267965-84sotgds	320	4	two	two	CD
cord-267965-84sotgds	320	5	decades	decade	NNS
cord-267965-84sotgds	320	6	since	since	IN
cord-267965-84sotgds	320	7	the	the	DT
cord-267965-84sotgds	320	8	CC	CC	NNP
cord-267965-84sotgds	320	9	was	be	VBD
cord-267965-84sotgds	320	10	conceptualized	conceptualize	VBN
cord-267965-84sotgds	320	11	(	(	-LRB-
cord-267965-84sotgds	320	12	Churchill	Churchill	NNP
cord-267965-84sotgds	320	13	et	et	NNP
cord-267965-84sotgds	320	14	al	al	NNP
cord-267965-84sotgds	320	15	.	.	NNP
cord-267965-84sotgds	320	16	,	,	,
cord-267965-84sotgds	320	17	2004	2004	CD
cord-267965-84sotgds	320	18	)	)	-RRB-
cord-267965-84sotgds	320	19	,	,	,
cord-267965-84sotgds	320	20	the	the	DT
cord-267965-84sotgds	320	21	CC	CC	NNP
cord-267965-84sotgds	320	22	has	have	VBZ
cord-267965-84sotgds	320	23	proven	prove	VBN
cord-267965-84sotgds	320	24	to	to	TO
cord-267965-84sotgds	320	25	be	be	VB
cord-267965-84sotgds	320	26	a	a	DT
cord-267965-84sotgds	320	27	fruitful	fruitful	JJ
cord-267965-84sotgds	320	28	resource	resource	NN
cord-267965-84sotgds	320	29	across	across	IN
cord-267965-84sotgds	320	30	many	many	JJ
cord-267965-84sotgds	320	31	fields	field	NNS
cord-267965-84sotgds	320	32	,	,	,
cord-267965-84sotgds	320	33	including	include	VBG
cord-267965-84sotgds	320	34	infectious	infectious	JJ
cord-267965-84sotgds	320	35	disease	disease	NN
cord-267965-84sotgds	320	36	and	and	CC
cord-267965-84sotgds	320	37	immunology	immunology	NN
cord-267965-84sotgds	320	38	.	.	.
cord-267965-84sotgds	321	1	Expanding	expand	VBG
cord-267965-84sotgds	321	2	use	use	NN
cord-267965-84sotgds	321	3	of	of	IN
cord-267965-84sotgds	321	4	the	the	DT
cord-267965-84sotgds	321	5	CC	CC	NNP
cord-267965-84sotgds	321	6	has	have	VBZ
cord-267965-84sotgds	321	7	highlighted	highlight	VBN
cord-267965-84sotgds	321	8	certain	certain	JJ
cord-267965-84sotgds	321	9	challenges	challenge	NNS
cord-267965-84sotgds	321	10	and	and	CC
cord-267965-84sotgds	321	11	considerations	consideration	NNS
cord-267965-84sotgds	321	12	that	that	WDT
cord-267965-84sotgds	321	13	should	should	MD
cord-267965-84sotgds	321	14	be	be	VB
cord-267965-84sotgds	321	15	recognized	recognize	VBN
cord-267965-84sotgds	321	16	to	to	TO
cord-267965-84sotgds	321	17	drive	drive	VB
cord-267965-84sotgds	321	18	future	future	JJ
cord-267965-84sotgds	321	19	development	development	NN
cord-267965-84sotgds	321	20	in	in	IN
cord-267965-84sotgds	321	21	both	both	DT
cord-267965-84sotgds	321	22	experimental	experimental	JJ
cord-267965-84sotgds	321	23	design	design	NN
cord-267965-84sotgds	321	24	and	and	CC
cord-267965-84sotgds	321	25	resource	resource	NN
cord-267965-84sotgds	321	26	expansion	expansion	NN
cord-267965-84sotgds	321	27	.	.	.
cord-267965-84sotgds	322	1	(	(	-LRB-
cord-267965-84sotgds	322	2	1	1	LS
cord-267965-84sotgds	322	3	)	)	-RRB-
cord-267965-84sotgds	322	4	Small	small	JJ
cord-267965-84sotgds	322	5	screen	screen	NN
cord-267965-84sotgds	322	6	in	in	IN
cord-267965-84sotgds	322	7	a	a	DT
cord-267965-84sotgds	322	8	subset	subset	NN
cord-267965-84sotgds	322	9	of	of	IN
cord-267965-84sotgds	322	10	CC	cc	NN
cord-267965-84sotgds	322	11	strains	strain	NNS
cord-267965-84sotgds	322	12	(	(	-LRB-
cord-267965-84sotgds	322	13	12	12	CD
cord-267965-84sotgds	322	14	-	-	SYM
cord-267965-84sotgds	322	15	16	16	CD
cord-267965-84sotgds	322	16	)	)	-RRB-
cord-267965-84sotgds	322	17	,	,	,
cord-267965-84sotgds	322	18	selected	select	VBN
cord-267965-84sotgds	322	19	based	base	VBN
cord-267965-84sotgds	322	20	on	on	IN
cord-267965-84sotgds	322	21	availability	availability	NN
cord-267965-84sotgds	322	22	or	or	CC
cord-267965-84sotgds	322	23	a	a	DT
cord-267965-84sotgds	322	24	genotype	genotype	NN
cord-267965-84sotgds	322	25	of	of	IN
cord-267965-84sotgds	322	26	interest	interest	NN
cord-267965-84sotgds	322	27	(	(	-LRB-
cord-267965-84sotgds	322	28	e.g.	e.g.	RB
cord-267965-84sotgds	322	29	,	,	,
cord-267965-84sotgds	322	30	MHC	MHC	NNP
cord-267965-84sotgds	322	31	haplotype	haplotype	NN
cord-267965-84sotgds	322	32	)	)	-RRB-
cord-267965-84sotgds	322	33	.	.	.
cord-267965-84sotgds	323	1	(	(	-LRB-
cord-267965-84sotgds	323	2	2	2	LS
cord-267965-84sotgds	323	3	)	)	-RRB-
cord-267965-84sotgds	323	4	Assess	assess	VB
cord-267965-84sotgds	323	5	variation	variation	NN
cord-267965-84sotgds	323	6	across	across	IN
cord-267965-84sotgds	323	7	strains	strain	NNS
cord-267965-84sotgds	323	8	,	,	,
cord-267965-84sotgds	323	9	identify	identify	VB
cord-267965-84sotgds	323	10	outliers	outlier	NNS
cord-267965-84sotgds	323	11	,	,	,
cord-267965-84sotgds	323	12	measure	measure	VB
cord-267965-84sotgds	323	13	heritability	heritability	NN
cord-267965-84sotgds	323	14	,	,	,
cord-267965-84sotgds	323	15	perform	perform	VB
cord-267965-84sotgds	323	16	power	power	NN
cord-267965-84sotgds	323	17	calculations	calculation	NNS
cord-267965-84sotgds	323	18	,	,	,
cord-267965-84sotgds	323	19	and	and	CC
cord-267965-84sotgds	323	20	identify	identify	VB
cord-267965-84sotgds	323	21	confounding	confounding	JJ
cord-267965-84sotgds	323	22	variables	variable	NNS
cord-267965-84sotgds	323	23	and	and	CC
cord-267965-84sotgds	323	24	reassess	reassess	VB
cord-267965-84sotgds	323	25	experimental	experimental	JJ
cord-267965-84sotgds	323	26	design	design	NN
cord-267965-84sotgds	323	27	if	if	IN
cord-267965-84sotgds	323	28	necessary	necessary	JJ
cord-267965-84sotgds	323	29	.	.	.
cord-267965-84sotgds	324	1	(	(	-LRB-
cord-267965-84sotgds	324	2	3	3	LS
cord-267965-84sotgds	324	3	)	)	-RRB-
cord-267965-84sotgds	324	4	Perform	perform	VB
cord-267965-84sotgds	324	5	a	a	DT
cord-267965-84sotgds	324	6	larger	large	JJR
cord-267965-84sotgds	324	7	screen	screen	NN
cord-267965-84sotgds	324	8	either	either	CC
cord-267965-84sotgds	324	9	in	in	IN
cord-267965-84sotgds	324	10	the	the	DT
cord-267965-84sotgds	324	11	full	full	JJ
cord-267965-84sotgds	324	12	CC	CC	NNP
cord-267965-84sotgds	324	13	population	population	NN
cord-267965-84sotgds	324	14	or	or	CC
cord-267965-84sotgds	324	15	a	a	DT
cord-267965-84sotgds	324	16	targeted	target	VBN
cord-267965-84sotgds	324	17	intercross	intercross	NN
cord-267965-84sotgds	324	18	.	.	.
cord-267965-84sotgds	325	1	Following	follow	VBG
cord-267965-84sotgds	325	2	mapping	mapping	NN
cord-267965-84sotgds	325	3	,	,	,
cord-267965-84sotgds	325	4	this	this	DT
cord-267965-84sotgds	325	5	can	can	MD
cord-267965-84sotgds	325	6	be	be	VB
cord-267965-84sotgds	325	7	repeated	repeat	VBN
cord-267965-84sotgds	325	8	to	to	TO
cord-267965-84sotgds	325	9	follow	follow	VB
cord-267965-84sotgds	325	10	-	-	HYPH
cord-267965-84sotgds	325	11	up	up	NN
cord-267965-84sotgds	325	12	on	on	IN
cord-267965-84sotgds	325	13	modifier	modifier	NN
cord-267965-84sotgds	325	14	alleles	allele	NNS
cord-267965-84sotgds	325	15	or	or	CC
cord-267965-84sotgds	325	16	other	other	JJ
cord-267965-84sotgds	325	17	unexplained	unexplained	JJ
cord-267965-84sotgds	325	18	loci	locus	NNS
cord-267965-84sotgds	325	19	.	.	.
cord-267965-84sotgds	326	1	(	(	-LRB-
cord-267965-84sotgds	326	2	4	4	LS
cord-267965-84sotgds	326	3	)	)	-RRB-
cord-267965-84sotgds	326	4	Reassess	reassess	VB
cord-267965-84sotgds	326	5	variation	variation	NN
cord-267965-84sotgds	326	6	,	,	,
cord-267965-84sotgds	326	7	outliers	outlier	NNS
cord-267965-84sotgds	326	8	,	,	,
cord-267965-84sotgds	326	9	and	and	CC
cord-267965-84sotgds	326	10	heritability	heritability	NN
cord-267965-84sotgds	326	11	across	across	IN
cord-267965-84sotgds	326	12	mapping	map	VBG
cord-267965-84sotgds	326	13	population	population	NN
cord-267965-84sotgds	326	14	.	.	.
cord-267965-84sotgds	327	1	(	(	-LRB-
cord-267965-84sotgds	327	2	5	5	LS
cord-267965-84sotgds	327	3	)	)	-RRB-
cord-267965-84sotgds	327	4	Map	map	NN
cord-267965-84sotgds	327	5	QTLs	qtl	NNS
cord-267965-84sotgds	327	6	driving	drive	VBG
cord-267965-84sotgds	327	7	phenotype	phenotype	NN
cord-267965-84sotgds	327	8	of	of	IN
cord-267965-84sotgds	327	9	interest	interest	NN
cord-267965-84sotgds	327	10	;	;	:
cord-267965-84sotgds	327	11	analyze	analyze	VB
cord-267965-84sotgds	327	12	founder	founder	NN
cord-267965-84sotgds	327	13	haplotype	haplotype	NN
cord-267965-84sotgds	327	14	effects	effect	NNS
cord-267965-84sotgds	327	15	if	if	IN
cord-267965-84sotgds	327	16	mapping	mapping	NN
cord-267965-84sotgds	327	17	is	be	VBZ
cord-267965-84sotgds	327	18	done	do	VBN
cord-267965-84sotgds	327	19	in	in	IN
cord-267965-84sotgds	327	20	the	the	DT
cord-267965-84sotgds	327	21	CC	cc	NN
cord-267965-84sotgds	327	22	.	.	.
cord-267965-84sotgds	328	1	(	(	-LRB-
cord-267965-84sotgds	328	2	6	6	LS
cord-267965-84sotgds	328	3	)	)	-RRB-
cord-267965-84sotgds	328	4	Rationally	rationally	RB
cord-267965-84sotgds	328	5	select	select	JJ
cord-267965-84sotgds	328	6	candidate	candidate	NN
cord-267965-84sotgds	328	7	genes	gene	NNS
cord-267965-84sotgds	328	8	using	use	VBG
cord-267965-84sotgds	328	9	different	different	JJ
cord-267965-84sotgds	328	10	tools	tool	NNS
cord-267965-84sotgds	328	11	as	as	IN
cord-267965-84sotgds	328	12	applicable	applicable	JJ
cord-267965-84sotgds	328	13	.	.	.
cord-267965-84sotgds	329	1	(	(	-LRB-
cord-267965-84sotgds	329	2	7	7	LS
cord-267965-84sotgds	329	3	)	)	-RRB-
cord-267965-84sotgds	329	4	Perform	perform	VB
cord-267965-84sotgds	329	5	validation	validation	NN
cord-267965-84sotgds	329	6	studies	study	NNS
cord-267965-84sotgds	329	7	in	in	IN
cord-267965-84sotgds	329	8	vitro	vitro	FW
cord-267965-84sotgds	329	9	and/or	and/or	CC
cord-267965-84sotgds	329	10	in	in	IN
cord-267965-84sotgds	329	11	vivo	vivo	NN
cord-267965-84sotgds	329	12	to	to	TO
cord-267965-84sotgds	329	13	confirm	confirm	VB
cord-267965-84sotgds	329	14	effect	effect	NN
cord-267965-84sotgds	329	15	of	of	IN
cord-267965-84sotgds	329	16	candidate	candidate	NN
cord-267965-84sotgds	329	17	gene	gene	NN
cord-267965-84sotgds	329	18	on	on	IN
cord-267965-84sotgds	329	19	phenotype	phenotype	NN
cord-267965-84sotgds	329	20	.	.	.
cord-267965-84sotgds	330	1	Genetic	genetic	JJ
cord-267965-84sotgds	330	2	mapping	mapping	NN
cord-267965-84sotgds	330	3	studies	study	NNS
cord-267965-84sotgds	330	4	in	in	IN
cord-267965-84sotgds	330	5	the	the	DT
cord-267965-84sotgds	330	6	CC	CC	NNP
cord-267965-84sotgds	330	7	have	have	VBP
cord-267965-84sotgds	330	8	successfully	successfully	RB
cord-267965-84sotgds	330	9	identified	identify	VBN
cord-267965-84sotgds	330	10	loci	locus	NNS
cord-267965-84sotgds	330	11	underlying	underlie	VBG
cord-267965-84sotgds	330	12	infectious	infectious	JJ
cord-267965-84sotgds	330	13	disease	disease	NN
cord-267965-84sotgds	330	14	and	and	CC
cord-267965-84sotgds	330	15	immune	immune	JJ
cord-267965-84sotgds	330	16	phenotypes	phenotype	NNS
cord-267965-84sotgds	330	17	;	;	:
cord-267965-84sotgds	330	18	however	however	RB
cord-267965-84sotgds	330	19	,	,	,
cord-267965-84sotgds	330	20	relatively	relatively	RB
cord-267965-84sotgds	330	21	few	few	JJ
cord-267965-84sotgds	330	22	have	have	VBP
cord-267965-84sotgds	330	23	subsequently	subsequently	RB
cord-267965-84sotgds	330	24	validated	validate	VBN
cord-267965-84sotgds	330	25	the	the	DT
cord-267965-84sotgds	330	26	initially	initially	RB
cord-267965-84sotgds	330	27	identified	identify	VBN
cord-267965-84sotgds	330	28	candidate	candidate	NN
cord-267965-84sotgds	330	29	genes	gene	NNS
cord-267965-84sotgds	330	30	.	.	.
cord-267965-84sotgds	331	1	Even	even	RB
cord-267965-84sotgds	331	2	more	more	RBR
cord-267965-84sotgds	331	3	challenging	challenging	JJ
cord-267965-84sotgds	331	4	than	than	IN
cord-267965-84sotgds	331	5	candidate	candidate	NN
cord-267965-84sotgds	331	6	gene	gene	NN
cord-267965-84sotgds	331	7	validation	validation	NN
cord-267965-84sotgds	331	8	is	be	VBZ
cord-267965-84sotgds	331	9	the	the	DT
cord-267965-84sotgds	331	10	identification	identification	NN
cord-267965-84sotgds	331	11	of	of	IN
cord-267965-84sotgds	331	12	specific	specific	JJ
cord-267965-84sotgds	331	13	causal	causal	JJ
cord-267965-84sotgds	331	14	variants	variant	NNS
cord-267965-84sotgds	331	15	within	within	IN
cord-267965-84sotgds	331	16	a	a	DT
cord-267965-84sotgds	331	17	gene	gene	NN
cord-267965-84sotgds	331	18	.	.	.
cord-267965-84sotgds	332	1	While	while	IN
cord-267965-84sotgds	332	2	strategies	strategy	NNS
cord-267965-84sotgds	332	3	such	such	JJ
cord-267965-84sotgds	332	4	as	as	IN
cord-267965-84sotgds	332	5	merge	merge	NN
cord-267965-84sotgds	332	6	analysis	analysis	NN
cord-267965-84sotgds	332	7	can	can	MD
cord-267965-84sotgds	332	8	help	help	VB
cord-267965-84sotgds	332	9	refine	refine	VB
cord-267965-84sotgds	332	10	candidates	candidate	NNS
cord-267965-84sotgds	332	11	and	and	CC
cord-267965-84sotgds	332	12	variants	variant	NNS
cord-267965-84sotgds	332	13	,	,	,
cord-267965-84sotgds	332	14	these	these	DT
cord-267965-84sotgds	332	15	tools	tool	NNS
cord-267965-84sotgds	332	16	are	be	VBP
cord-267965-84sotgds	332	17	not	not	RB
cord-267965-84sotgds	332	18	always	always	RB
cord-267965-84sotgds	332	19	informative	informative	JJ
cord-267965-84sotgds	332	20	.	.	.
cord-267965-84sotgds	333	1	There	there	EX
cord-267965-84sotgds	333	2	is	be	VBZ
cord-267965-84sotgds	333	3	a	a	DT
cord-267965-84sotgds	333	4	need	need	NN
cord-267965-84sotgds	333	5	for	for	IN
cord-267965-84sotgds	333	6	more	more	JJR
cord-267965-84sotgds	333	7	refinement	refinement	NN
cord-267965-84sotgds	333	8	methodologies	methodology	NNS
cord-267965-84sotgds	333	9	that	that	WDT
cord-267965-84sotgds	333	10	can	can	MD
cord-267965-84sotgds	333	11	be	be	VB
cord-267965-84sotgds	333	12	applied	apply	VBN
cord-267965-84sotgds	333	13	in	in	IN
cord-267965-84sotgds	333	14	combination	combination	NN
cord-267965-84sotgds	333	15	with	with	IN
cord-267965-84sotgds	333	16	experimental	experimental	JJ
cord-267965-84sotgds	333	17	validation	validation	NN
cord-267965-84sotgds	333	18	to	to	TO
cord-267965-84sotgds	333	19	narrow	narrow	VB
cord-267965-84sotgds	333	20	and	and	CC
cord-267965-84sotgds	333	21	identify	identify	VB
cord-267965-84sotgds	333	22	causal	causal	JJ
cord-267965-84sotgds	333	23	variants	variant	NNS
cord-267965-84sotgds	333	24	.	.	.
cord-267965-84sotgds	334	1	The	the	DT
cord-267965-84sotgds	334	2	wide	wide	JJ
cord-267965-84sotgds	334	3	array	array	NN
cord-267965-84sotgds	334	4	of	of	IN
cord-267965-84sotgds	334	5	genomic	genomic	JJ
cord-267965-84sotgds	334	6	,	,	,
cord-267965-84sotgds	334	7	molecular	molecular	JJ
cord-267965-84sotgds	334	8	,	,	,
cord-267965-84sotgds	334	9	and	and	CC
cord-267965-84sotgds	334	10	immunological	immunological	JJ
cord-267965-84sotgds	334	11	reagents	reagent	NNS
cord-267965-84sotgds	334	12	available	available	JJ
cord-267965-84sotgds	334	13	is	be	VBZ
cord-267965-84sotgds	334	14	a	a	DT
cord-267965-84sotgds	334	15	valuable	valuable	JJ
cord-267965-84sotgds	334	16	asset	asset	NN
cord-267965-84sotgds	334	17	for	for	IN
cord-267965-84sotgds	334	18	mouse	mouse	NN
cord-267965-84sotgds	334	19	research	research	NN
cord-267965-84sotgds	334	20	;	;	:
cord-267965-84sotgds	334	21	however	however	RB
cord-267965-84sotgds	334	22	,	,	,
cord-267965-84sotgds	334	23	these	these	DT
cord-267965-84sotgds	334	24	do	do	VBP
cord-267965-84sotgds	334	25	not	not	RB
cord-267965-84sotgds	334	26	necessarily	necessarily	RB
cord-267965-84sotgds	334	27	uniformly	uniformly	RB
cord-267965-84sotgds	334	28	work	work	NN
cord-267965-84sotgds	334	29	across	across	IN
cord-267965-84sotgds	334	30	the	the	DT
cord-267965-84sotgds	334	31	CC	cc	NN
cord-267965-84sotgds	334	32	and	and	CC
cord-267965-84sotgds	334	33	should	should	MD
cord-267965-84sotgds	334	34	be	be	VB
cord-267965-84sotgds	334	35	validated	validate	VBN
cord-267965-84sotgds	334	36	before	before	IN
cord-267965-84sotgds	334	37	use	use	NN
cord-267965-84sotgds	334	38	.	.	.
cord-267965-84sotgds	335	1	Existing	exist	VBG
cord-267965-84sotgds	335	2	CC	cc	NN
cord-267965-84sotgds	335	3	-	-	HYPH
cord-267965-84sotgds	335	4	specific	specific	JJ
cord-267965-84sotgds	335	5	resources	resource	NNS
cord-267965-84sotgds	335	6	,	,	,
cord-267965-84sotgds	335	7	such	such	JJ
cord-267965-84sotgds	335	8	as	as	IN
cord-267965-84sotgds	335	9	GECCO	GECCO	NNP
cord-267965-84sotgds	335	10	,	,	,
cord-267965-84sotgds	335	11	are	be	VBP
cord-267965-84sotgds	335	12	not	not	RB
cord-267965-84sotgds	335	13	necessarily	necessarily	RB
cord-267965-84sotgds	335	14	informative	informative	JJ
cord-267965-84sotgds	335	15	for	for	IN
cord-267965-84sotgds	335	16	infectious	infectious	JJ
cord-267965-84sotgds	335	17	disease	disease	NN
cord-267965-84sotgds	335	18	research	research	NN
cord-267965-84sotgds	335	19	since	since	IN
cord-267965-84sotgds	335	20	lymphoid	lymphoid	JJ
cord-267965-84sotgds	335	21	organs	organ	NNS
cord-267965-84sotgds	335	22	,	,	,
cord-267965-84sotgds	335	23	such	such	JJ
cord-267965-84sotgds	335	24	as	as	IN
cord-267965-84sotgds	335	25	the	the	DT
cord-267965-84sotgds	335	26	spleen	spleen	NN
cord-267965-84sotgds	335	27	,	,	,
cord-267965-84sotgds	335	28	thymus	thymus	NN
cord-267965-84sotgds	335	29	,	,	,
cord-267965-84sotgds	335	30	and	and	CC
cord-267965-84sotgds	335	31	bone	bone	NN
cord-267965-84sotgds	335	32	marrow	marrow	NN
cord-267965-84sotgds	335	33	,	,	,
cord-267965-84sotgds	335	34	are	be	VBP
cord-267965-84sotgds	335	35	not	not	RB
cord-267965-84sotgds	335	36	profiled	profile	VBN
cord-267965-84sotgds	335	37	.	.	.
cord-267965-84sotgds	336	1	Furthermore	furthermore	RB
cord-267965-84sotgds	336	2	,	,	,
cord-267965-84sotgds	336	3	the	the	DT
cord-267965-84sotgds	336	4	development	development	NN
cord-267965-84sotgds	336	5	of	of	IN
cord-267965-84sotgds	336	6	new	new	JJ
cord-267965-84sotgds	336	7	CC	cc	NN
cord-267965-84sotgds	336	8	-	-	HYPH
cord-267965-84sotgds	336	9	specific	specific	JJ
cord-267965-84sotgds	336	10	tools	tool	NNS
cord-267965-84sotgds	336	11	,	,	,
cord-267965-84sotgds	336	12	such	such	JJ
cord-267965-84sotgds	336	13	as	as	IN
cord-267965-84sotgds	336	14	CC	cc	NN
cord-267965-84sotgds	336	15	-	-	HYPH
cord-267965-84sotgds	336	16	derived	derive	VBN
cord-267965-84sotgds	336	17	cell	cell	NN
cord-267965-84sotgds	336	18	lines	line	NNS
cord-267965-84sotgds	336	19	(	(	-LRB-
cord-267965-84sotgds	336	20	e.g.	e.g.	RB
cord-267965-84sotgds	336	21	,	,	,
cord-267965-84sotgds	336	22	MEFs	mef	NNS
cord-267965-84sotgds	336	23	and	and	CC
cord-267965-84sotgds	336	24	IPSCs	IPSCs	NNP
cord-267965-84sotgds	336	25	)	)	-RRB-
cord-267965-84sotgds	336	26	,	,	,
cord-267965-84sotgds	336	27	will	will	MD
cord-267965-84sotgds	336	28	expand	expand	VB
cord-267965-84sotgds	336	29	the	the	DT
cord-267965-84sotgds	336	30	utility	utility	NN
cord-267965-84sotgds	336	31	of	of	IN
cord-267965-84sotgds	336	32	the	the	DT
cord-267965-84sotgds	336	33	CC	CC	NNP
cord-267965-84sotgds	336	34	across	across	IN
cord-267965-84sotgds	336	35	fields	field	NNS
cord-267965-84sotgds	336	36	,	,	,
cord-267965-84sotgds	336	37	including	include	VBG
cord-267965-84sotgds	336	38	the	the	DT
cord-267965-84sotgds	336	39	infectious	infectious	JJ
cord-267965-84sotgds	336	40	diseases	disease	NNS
cord-267965-84sotgds	336	41	and	and	CC
cord-267965-84sotgds	336	42	immunology	immunology	NN
cord-267965-84sotgds	336	43	fields	field	NNS
cord-267965-84sotgds	336	44	.	.	.
cord-267965-84sotgds	337	1	One	one	CD
cord-267965-84sotgds	337	2	of	of	IN
cord-267965-84sotgds	337	3	the	the	DT
cord-267965-84sotgds	337	4	largest	large	JJS
cord-267965-84sotgds	337	5	challenges	challenge	NNS
cord-267965-84sotgds	337	6	across	across	IN
cord-267965-84sotgds	337	7	all	all	DT
cord-267965-84sotgds	337	8	of	of	IN
cord-267965-84sotgds	337	9	model	model	NN
cord-267965-84sotgds	337	10	organism	organism	NN
cord-267965-84sotgds	337	11	research	research	NN
cord-267965-84sotgds	337	12	is	be	VBZ
cord-267965-84sotgds	337	13	connecting	connect	VBG
cord-267965-84sotgds	337	14	back	back	RB
cord-267965-84sotgds	337	15	to	to	IN
cord-267965-84sotgds	337	16	human	human	JJ
cord-267965-84sotgds	337	17	relevancy	relevancy	NN
cord-267965-84sotgds	337	18	.	.	.
cord-267965-84sotgds	338	1	The	the	DT
cord-267965-84sotgds	338	2	CC	CC	NNP
cord-267965-84sotgds	338	3	has	have	VBZ
cord-267965-84sotgds	338	4	already	already	RB
cord-267965-84sotgds	338	5	proven	prove	VBN
cord-267965-84sotgds	338	6	useful	useful	JJ
cord-267965-84sotgds	338	7	in	in	IN
cord-267965-84sotgds	338	8	providing	provide	VBG
cord-267965-84sotgds	338	9	improved	improve	VBN
cord-267965-84sotgds	338	10	models	model	NNS
cord-267965-84sotgds	338	11	of	of	IN
cord-267965-84sotgds	338	12	humanlike	humanlike	JJ
cord-267965-84sotgds	338	13	disease	disease	NN
cord-267965-84sotgds	338	14	,	,	,
cord-267965-84sotgds	338	15	as	as	IN
cord-267965-84sotgds	338	16	highlighted	highlight	VBN
cord-267965-84sotgds	338	17	above	above	RB
cord-267965-84sotgds	338	18	.	.	.
cord-267965-84sotgds	339	1	A	a	DT
cord-267965-84sotgds	339	2	number	number	NN
cord-267965-84sotgds	339	3	of	of	IN
cord-267965-84sotgds	339	4	genes	gene	NNS
cord-267965-84sotgds	339	5	that	that	WDT
cord-267965-84sotgds	339	6	have	have	VBP
cord-267965-84sotgds	339	7	been	be	VBN
cord-267965-84sotgds	339	8	highlighted	highlight	VBN
cord-267965-84sotgds	339	9	in	in	IN
cord-267965-84sotgds	339	10	the	the	DT
cord-267965-84sotgds	339	11	CC	CC	NNP
cord-267965-84sotgds	339	12	,	,	,
cord-267965-84sotgds	339	13	such	such	JJ
cord-267965-84sotgds	339	14	as	as	IN
cord-267965-84sotgds	339	15	Mx1	mx1	JJ
cord-267965-84sotgds	339	16	and	and	CC
cord-267965-84sotgds	339	17	Oas1b	Oas1b	NNP
cord-267965-84sotgds	339	18	,	,	,
cord-267965-84sotgds	339	19	have	have	VBP
cord-267965-84sotgds	339	20	human	human	JJ
cord-267965-84sotgds	339	21	paralogs	paralog	NNS
cord-267965-84sotgds	339	22	relevant	relevant	JJ
cord-267965-84sotgds	339	23	in	in	IN
cord-267965-84sotgds	339	24	infectious	infectious	JJ
cord-267965-84sotgds	339	25	disease	disease	NN
cord-267965-84sotgds	339	26	susceptibility	susceptibility	NN
cord-267965-84sotgds	339	27	(	(	-LRB-
cord-267965-84sotgds	339	28	Lin	Lin	NNP
cord-267965-84sotgds	339	29	and	and	CC
cord-267965-84sotgds	339	30	Brass	Brass	NNP
cord-267965-84sotgds	339	31	,	,	,
cord-267965-84sotgds	339	32	2013	2013	CD
cord-267965-84sotgds	339	33	;	;	:
cord-267965-84sotgds	339	34	Simon	Simon	NNP
cord-267965-84sotgds	339	35	-	-	HYPH
cord-267965-84sotgds	339	36	Loriere	Loriere	NNP
cord-267965-84sotgds	339	37	et	et	FW
cord-267965-84sotgds	339	38	al	al	NNP
cord-267965-84sotgds	339	39	.	.	NNP
cord-267965-84sotgds	339	40	,	,	,
cord-267965-84sotgds	339	41	2015	2015	CD
cord-267965-84sotgds	339	42	)	)	-RRB-
cord-267965-84sotgds	339	43	,	,	,
cord-267965-84sotgds	339	44	demonstrating	demonstrate	VBG
cord-267965-84sotgds	339	45	the	the	DT
cord-267965-84sotgds	339	46	overlap	overlap	NN
cord-267965-84sotgds	339	47	between	between	IN
cord-267965-84sotgds	339	48	important	important	JJ
cord-267965-84sotgds	339	49	genetically	genetically	RB
cord-267965-84sotgds	339	50	diverse	diverse	JJ
cord-267965-84sotgds	339	51	infectious	infectious	JJ
cord-267965-84sotgds	339	52	disease	disease	NN
cord-267965-84sotgds	339	53	pathways	pathway	NNS
cord-267965-84sotgds	339	54	in	in	IN
cord-267965-84sotgds	339	55	mouse	mouse	NN
cord-267965-84sotgds	339	56	and	and	CC
cord-267965-84sotgds	339	57	humans	human	NNS
cord-267965-84sotgds	339	58	.	.	.
cord-267965-84sotgds	340	1	However	however	RB
cord-267965-84sotgds	340	2	,	,	,
cord-267965-84sotgds	340	3	the	the	DT
cord-267965-84sotgds	340	4	majority	majority	NN
cord-267965-84sotgds	340	5	of	of	IN
cord-267965-84sotgds	340	6	studies	study	NNS
cord-267965-84sotgds	340	7	have	have	VBP
cord-267965-84sotgds	340	8	not	not	RB
cord-267965-84sotgds	340	9	yet	yet	RB
cord-267965-84sotgds	340	10	made	make	VBN
cord-267965-84sotgds	340	11	direct	direct	JJ
cord-267965-84sotgds	340	12	connections	connection	NNS
cord-267965-84sotgds	340	13	back	back	RB
cord-267965-84sotgds	340	14	to	to	IN
cord-267965-84sotgds	340	15	human	human	JJ
cord-267965-84sotgds	340	16	datasets	dataset	NNS
cord-267965-84sotgds	340	17	.	.	.
cord-267965-84sotgds	341	1	As	as	IN
cord-267965-84sotgds	341	2	CC	CC	NNP
cord-267965-84sotgds	341	3	research	research	NN
cord-267965-84sotgds	341	4	develops	develop	VBZ
cord-267965-84sotgds	341	5	,	,	,
cord-267965-84sotgds	341	6	it	-PRON-	PRP
cord-267965-84sotgds	341	7	will	will	MD
cord-267965-84sotgds	341	8	be	be	VB
cord-267965-84sotgds	341	9	increasingly	increasingly	RB
cord-267965-84sotgds	341	10	important	important	JJ
cord-267965-84sotgds	341	11	to	to	TO
cord-267965-84sotgds	341	12	continue	continue	VB
cord-267965-84sotgds	341	13	to	to	TO
cord-267965-84sotgds	341	14	extend	extend	VB
cord-267965-84sotgds	341	15	analysis	analysis	NN
cord-267965-84sotgds	341	16	from	from	IN
cord-267965-84sotgds	341	17	the	the	DT
cord-267965-84sotgds	341	18	CC	CC	NNP
cord-267965-84sotgds	341	19	to	to	IN
cord-267965-84sotgds	341	20	human	human	JJ
cord-267965-84sotgds	341	21	genetics	genetic	NNS
cord-267965-84sotgds	341	22	and	and	CC
cord-267965-84sotgds	341	23	vice	vice	NN
cord-267965-84sotgds	341	24	versa	versa	RB
cord-267965-84sotgds	341	25	.	.	.
cord-267965-84sotgds	342	1	This	this	DT
cord-267965-84sotgds	342	2	will	will	MD
cord-267965-84sotgds	342	3	require	require	VB
cord-267965-84sotgds	342	4	more	more	JJR
cord-267965-84sotgds	342	5	crosstalk	crosstalk	NN
cord-267965-84sotgds	342	6	between	between	IN
cord-267965-84sotgds	342	7	mouse	mouse	NN
cord-267965-84sotgds	342	8	and	and	CC
cord-267965-84sotgds	342	9	human	human	NN
cord-267965-84sotgds	342	10	geneticists	geneticist	NNS
cord-267965-84sotgds	342	11	to	to	TO
cord-267965-84sotgds	342	12	bridge	bridge	VB
cord-267965-84sotgds	342	13	gaps	gap	NNS
cord-267965-84sotgds	342	14	in	in	IN
cord-267965-84sotgds	342	15	research	research	NN
cord-267965-84sotgds	342	16	and	and	CC
cord-267965-84sotgds	342	17	communication	communication	NN
cord-267965-84sotgds	342	18	.	.	.
cord-267965-84sotgds	343	1	Host	host	NN
cord-267965-84sotgds	343	2	immunity	immunity	NN
cord-267965-84sotgds	343	3	and	and	CC
cord-267965-84sotgds	343	4	susceptibility	susceptibility	NN
cord-267965-84sotgds	343	5	to	to	IN
cord-267965-84sotgds	343	6	infectious	infectious	JJ
cord-267965-84sotgds	343	7	disease	disease	NN
cord-267965-84sotgds	343	8	is	be	VBZ
cord-267965-84sotgds	343	9	a	a	DT
cord-267965-84sotgds	343	10	complex	complex	JJ
cord-267965-84sotgds	343	11	response	response	NN
cord-267965-84sotgds	343	12	driven	drive	VBN
cord-267965-84sotgds	343	13	by	by	IN
cord-267965-84sotgds	343	14	a	a	DT
cord-267965-84sotgds	343	15	multitude	multitude	NN
cord-267965-84sotgds	343	16	of	of	IN
cord-267965-84sotgds	343	17	factors	factor	NNS
cord-267965-84sotgds	343	18	,	,	,
cord-267965-84sotgds	343	19	from	from	IN
cord-267965-84sotgds	343	20	environment	environment	NN
cord-267965-84sotgds	343	21	and	and	CC
cord-267965-84sotgds	343	22	immune	immune	JJ
cord-267965-84sotgds	343	23	experience	experience	NN
cord-267965-84sotgds	343	24	to	to	IN
cord-267965-84sotgds	343	25	the	the	DT
cord-267965-84sotgds	343	26	genetics	genetic	NNS
cord-267965-84sotgds	343	27	of	of	IN
cord-267965-84sotgds	343	28	both	both	CC
cord-267965-84sotgds	343	29	the	the	DT
cord-267965-84sotgds	343	30	pathogen	pathogen	NN
cord-267965-84sotgds	343	31	and	and	CC
cord-267965-84sotgds	343	32	the	the	DT
cord-267965-84sotgds	343	33	host	host	NN
cord-267965-84sotgds	343	34	.	.	.
cord-267965-84sotgds	344	1	Studying	study	VBG
cord-267965-84sotgds	344	2	the	the	DT
cord-267965-84sotgds	344	3	role	role	NN
cord-267965-84sotgds	344	4	of	of	IN
cord-267965-84sotgds	344	5	host	host	NN
cord-267965-84sotgds	344	6	genetics	genetic	NNS
cord-267965-84sotgds	344	7	in	in	IN
cord-267965-84sotgds	344	8	infectious	infectious	JJ
cord-267965-84sotgds	344	9	disease	disease	NN
cord-267965-84sotgds	344	10	directly	directly	RB
cord-267965-84sotgds	344	11	in	in	IN
cord-267965-84sotgds	344	12	humans	human	NNS
cord-267965-84sotgds	344	13	is	be	VBZ
cord-267965-84sotgds	344	14	challenging	challenging	JJ
cord-267965-84sotgds	344	15	because	because	IN
cord-267965-84sotgds	344	16	of	of	IN
cord-267965-84sotgds	344	17	this	this	DT
cord-267965-84sotgds	344	18	complexity	complexity	NN
cord-267965-84sotgds	344	19	,	,	,
cord-267965-84sotgds	344	20	and	and	CC
cord-267965-84sotgds	344	21	therefore	therefore	RB
cord-267965-84sotgds	344	22	much	much	JJ
cord-267965-84sotgds	344	23	of	of	IN
cord-267965-84sotgds	344	24	the	the	DT
cord-267965-84sotgds	344	25	research	research	NN
cord-267965-84sotgds	344	26	in	in	IN
cord-267965-84sotgds	344	27	the	the	DT
cord-267965-84sotgds	344	28	field	field	NN
cord-267965-84sotgds	344	29	leans	lean	VBZ
cord-267965-84sotgds	344	30	heavily	heavily	RB
cord-267965-84sotgds	344	31	on	on	IN
cord-267965-84sotgds	344	32	the	the	DT
cord-267965-84sotgds	344	33	mouse	mouse	NN
cord-267965-84sotgds	344	34	as	as	IN
cord-267965-84sotgds	344	35	a	a	DT
cord-267965-84sotgds	344	36	model	model	NN
cord-267965-84sotgds	344	37	organism	organism	NN
cord-267965-84sotgds	344	38	.	.	.
cord-267965-84sotgds	345	1	While	while	IN
cord-267965-84sotgds	345	2	the	the	DT
cord-267965-84sotgds	345	3	role	role	NN
cord-267965-84sotgds	345	4	of	of	IN
cord-267965-84sotgds	345	5	traditional	traditional	JJ
cord-267965-84sotgds	345	6	laboratory	laboratory	NN
cord-267965-84sotgds	345	7	strains	strain	NNS
cord-267965-84sotgds	345	8	and	and	CC
cord-267965-84sotgds	345	9	genetically	genetically	RB
cord-267965-84sotgds	345	10	modified	modify	VBN
cord-267965-84sotgds	345	11	mice	mouse	NNS
cord-267965-84sotgds	345	12	in	in	IN
cord-267965-84sotgds	345	13	driving	drive	VBG
cord-267965-84sotgds	345	14	advances	advance	NNS
cord-267965-84sotgds	345	15	in	in	IN
cord-267965-84sotgds	345	16	the	the	DT
cord-267965-84sotgds	345	17	field	field	NN
cord-267965-84sotgds	345	18	can	can	MD
cord-267965-84sotgds	345	19	not	not	RB
cord-267965-84sotgds	345	20	be	be	VB
cord-267965-84sotgds	345	21	understated	understate	VBN
cord-267965-84sotgds	345	22	,	,	,
cord-267965-84sotgds	345	23	these	these	DT
cord-267965-84sotgds	345	24	models	model	NNS
cord-267965-84sotgds	345	25	do	do	VBP
cord-267965-84sotgds	345	26	not	not	RB
cord-267965-84sotgds	345	27	capture	capture	VB
cord-267965-84sotgds	345	28	the	the	DT
cord-267965-84sotgds	345	29	genetic	genetic	JJ
cord-267965-84sotgds	345	30	diversity	diversity	NN
cord-267965-84sotgds	345	31	and	and	CC
cord-267965-84sotgds	345	32	phenotypic	phenotypic	NN
cord-267965-84sotgds	345	33	complexity	complexity	NN
cord-267965-84sotgds	345	34	observed	observe	VBN
cord-267965-84sotgds	345	35	in	in	IN
cord-267965-84sotgds	345	36	the	the	DT
cord-267965-84sotgds	345	37	natural	natural	JJ
cord-267965-84sotgds	345	38	population	population	NN
cord-267965-84sotgds	345	39	.	.	.
cord-267965-84sotgds	346	1	Building	build	VBG
cord-267965-84sotgds	346	2	on	on	IN
cord-267965-84sotgds	346	3	the	the	DT
cord-267965-84sotgds	346	4	success	success	NN
cord-267965-84sotgds	346	5	of	of	IN
cord-267965-84sotgds	346	6	classical	classical	JJ
cord-267965-84sotgds	346	7	intercrosses	intercrosse	NNS
cord-267965-84sotgds	346	8	and	and	CC
cord-267965-84sotgds	346	9	biparental	biparental	NNP
cord-267965-84sotgds	346	10	GRPs	GRPs	NNP
cord-267965-84sotgds	346	11	,	,	,
cord-267965-84sotgds	346	12	the	the	DT
cord-267965-84sotgds	346	13	CC	CC	NNP
cord-267965-84sotgds	346	14	is	be	VBZ
cord-267965-84sotgds	346	15	a	a	DT
cord-267965-84sotgds	346	16	highly	highly	RB
cord-267965-84sotgds	346	17	diverse	diverse	JJ
cord-267965-84sotgds	346	18	and	and	CC
cord-267965-84sotgds	346	19	reproducible	reproducible	JJ
cord-267965-84sotgds	346	20	resource	resource	NN
cord-267965-84sotgds	346	21	for	for	IN
cord-267965-84sotgds	346	22	studying	study	VBG
cord-267965-84sotgds	346	23	and	and	CC
cord-267965-84sotgds	346	24	mapping	map	VBG
cord-267965-84sotgds	346	25	complex	complex	JJ
cord-267965-84sotgds	346	26	traits	trait	NNS
cord-267965-84sotgds	346	27	,	,	,
cord-267965-84sotgds	346	28	including	include	VBG
cord-267965-84sotgds	346	29	infectious	infectious	JJ
cord-267965-84sotgds	346	30	disease	disease	NN
cord-267965-84sotgds	346	31	susceptibility	susceptibility	NN
cord-267965-84sotgds	346	32	.	.	.
cord-267965-84sotgds	347	1	The	the	DT
cord-267965-84sotgds	347	2	reproducibility	reproducibility	NN
cord-267965-84sotgds	347	3	of	of	IN
cord-267965-84sotgds	347	4	CC	cc	NN
cord-267965-84sotgds	347	5	strains	strain	NNS
cord-267965-84sotgds	347	6	will	will	MD
cord-267965-84sotgds	347	7	allow	allow	VB
cord-267965-84sotgds	347	8	the	the	DT
cord-267965-84sotgds	347	9	community	community	NN
cord-267965-84sotgds	347	10	to	to	TO
cord-267965-84sotgds	347	11	cross	cross	VB
cord-267965-84sotgds	347	12	-	-	VB
cord-267965-84sotgds	347	13	compare	compare	VB
cord-267965-84sotgds	347	14	genes	gene	NNS
cord-267965-84sotgds	347	15	and	and	CC
cord-267965-84sotgds	347	16	genetic	genetic	JJ
cord-267965-84sotgds	347	17	networks	network	NNS
cord-267965-84sotgds	347	18	that	that	WDT
cord-267965-84sotgds	347	19	regulate	regulate	VBP
cord-267965-84sotgds	347	20	response	response	NN
cord-267965-84sotgds	347	21	across	across	IN
cord-267965-84sotgds	347	22	pathogens	pathogen	NNS
cord-267965-84sotgds	347	23	(	(	-LRB-
cord-267965-84sotgds	347	24	e.g.	e.g.	RB
cord-267965-84sotgds	347	25	,	,	,
cord-267965-84sotgds	347	26	IAV	IAV	NNP
cord-267965-84sotgds	347	27	and	and	CC
cord-267965-84sotgds	347	28	SARS	SARS	NNP
cord-267965-84sotgds	347	29	-	-	HYPH
cord-267965-84sotgds	347	30	CoV	CoV	NNP
cord-267965-84sotgds	347	31	;	;	:
cord-267965-84sotgds	347	32	Xiong	Xiong	NNP
cord-267965-84sotgds	347	33	et	et	NNP
cord-267965-84sotgds	347	34	al	al	NNP
cord-267965-84sotgds	347	35	.	.	NNP
cord-267965-84sotgds	347	36	,	,	,
cord-267965-84sotgds	347	37	2014	2014	CD
cord-267965-84sotgds	347	38	)	)	-RRB-
cord-267965-84sotgds	347	39	,	,	,
cord-267965-84sotgds	347	40	while	while	IN
cord-267965-84sotgds	347	41	also	also	RB
cord-267965-84sotgds	347	42	exploring	explore	VBG
cord-267965-84sotgds	347	43	the	the	DT
cord-267965-84sotgds	347	44	impact	impact	NN
cord-267965-84sotgds	347	45	of	of	IN
cord-267965-84sotgds	347	46	factors	factor	NNS
cord-267965-84sotgds	347	47	such	such	JJ
cord-267965-84sotgds	347	48	as	as	IN
cord-267965-84sotgds	347	49	the	the	DT
cord-267965-84sotgds	347	50	microbiome	microbiome	NN
cord-267965-84sotgds	347	51	,	,	,
cord-267965-84sotgds	347	52	co	co	NNS
cord-267965-84sotgds	347	53	-	-	NNS
cord-267965-84sotgds	347	54	infections	infection	NNS
cord-267965-84sotgds	347	55	,	,	,
cord-267965-84sotgds	347	56	and	and	CC
cord-267965-84sotgds	347	57	genetic	genetic	JJ
cord-267965-84sotgds	347	58	variation	variation	NN
cord-267965-84sotgds	347	59	of	of	IN
cord-267965-84sotgds	347	60	the	the	DT
cord-267965-84sotgds	347	61	pathogen	pathogen	NN
cord-267965-84sotgds	347	62	in	in	IN
cord-267965-84sotgds	347	63	the	the	DT
cord-267965-84sotgds	347	64	context	context	NN
cord-267965-84sotgds	347	65	of	of	IN
cord-267965-84sotgds	347	66	a	a	DT
cord-267965-84sotgds	347	67	controlled	control	VBN
cord-267965-84sotgds	347	68	,	,	,
cord-267965-84sotgds	347	69	genetically	genetically	RB
cord-267965-84sotgds	347	70	diverse	diverse	JJ
cord-267965-84sotgds	347	71	model	model	NN
cord-267965-84sotgds	347	72	population	population	NN
cord-267965-84sotgds	347	73	.	.	.
cord-267965-84sotgds	348	1	The	the	DT
cord-267965-84sotgds	348	2	CC	CC	NNP
cord-267965-84sotgds	348	3	also	also	RB
cord-267965-84sotgds	348	4	holds	hold	VBZ
cord-267965-84sotgds	348	5	promise	promise	NN
cord-267965-84sotgds	348	6	for	for	IN
cord-267965-84sotgds	348	7	the	the	DT
cord-267965-84sotgds	348	8	development	development	NN
cord-267965-84sotgds	348	9	of	of	IN
cord-267965-84sotgds	348	10	new	new	JJ
cord-267965-84sotgds	348	11	models	model	NNS
cord-267965-84sotgds	348	12	and	and	CC
cord-267965-84sotgds	348	13	testing	testing	NN
cord-267965-84sotgds	348	14	platforms	platform	NNS
cord-267965-84sotgds	348	15	that	that	WDT
cord-267965-84sotgds	348	16	will	will	MD
cord-267965-84sotgds	348	17	better	better	RB
cord-267965-84sotgds	348	18	reproduce	reproduce	VB
cord-267965-84sotgds	348	19	specific	specific	JJ
cord-267965-84sotgds	348	20	human	human	JJ
cord-267965-84sotgds	348	21	disease	disease	NN
cord-267965-84sotgds	348	22	outcomes	outcome	NNS
cord-267965-84sotgds	348	23	or	or	CC
cord-267965-84sotgds	348	24	host	host	NN
cord-267965-84sotgds	348	25	responses	response	NNS
cord-267965-84sotgds	348	26	to	to	IN
cord-267965-84sotgds	348	27	pathogens	pathogen	NNS
cord-267965-84sotgds	348	28	and	and	CC
cord-267965-84sotgds	348	29	vaccines	vaccine	NNS
cord-267965-84sotgds	348	30	.	.	.
cord-267965-84sotgds	349	1	Trolling	troll	VBG
cord-267965-84sotgds	349	2	for	for	IN
cord-267965-84sotgds	349	3	the	the	DT
cord-267965-84sotgds	349	4	ideal	ideal	JJ
cord-267965-84sotgds	349	5	model	model	NN
cord-267965-84sotgds	349	6	host	host	NN
cord-267965-84sotgds	349	7	:	:	:
cord-267965-84sotgds	350	1	zebrafish	zebrafish	NNS
cord-267965-84sotgds	350	2	take	take	VBP
cord-267965-84sotgds	350	3	the	the	DT
cord-267965-84sotgds	350	4	bait	bait	NN
cord-267965-84sotgds	350	5	R	r	NN
cord-267965-84sotgds	350	6	/	/	SYM
cord-267965-84sotgds	350	7	qtl	qtl	NN
cord-267965-84sotgds	350	8	:	:	:
cord-267965-84sotgds	350	9	highthroughput	highthroughput	NN
cord-267965-84sotgds	350	10	multiple	multiple	JJ
cord-267965-84sotgds	350	11	QTL	QTL	NNP
cord-267965-84sotgds	350	12	mapping	mapping	NN
cord-267965-84sotgds	350	13	Rare	Rare	NNP
cord-267965-84sotgds	350	14	variant	variant	NN
cord-267965-84sotgds	350	15	association	association	NN
cord-267965-84sotgds	350	16	studies	study	NNS
cord-267965-84sotgds	350	17	:	:	:
cord-267965-84sotgds	350	18	considerations	consideration	NNS
cord-267965-84sotgds	350	19	,	,	,
cord-267965-84sotgds	350	20	challenges	challenge	NNS
cord-267965-84sotgds	350	21	and	and	CC
cord-267965-84sotgds	350	22	opportunities	opportunity	NNS
cord-267965-84sotgds	350	23	Recombinant	recombinant	JJ
cord-267965-84sotgds	350	24	-	-	HYPH
cord-267965-84sotgds	350	25	inbred	inbred	JJ
cord-267965-84sotgds	350	26	strains	strain	NNS
cord-267965-84sotgds	350	27	.	.	.
cord-267965-84sotgds	351	1	An	an	DT
cord-267965-84sotgds	351	2	aid	aid	NN
cord-267965-84sotgds	351	3	to	to	IN
cord-267965-84sotgds	351	4	finding	find	VBG
cord-267965-84sotgds	351	5	identity	identity	NN
cord-267965-84sotgds	351	6	,	,	,
cord-267965-84sotgds	351	7	linkage	linkage	NN
cord-267965-84sotgds	351	8	,	,	,
cord-267965-84sotgds	351	9	and	and	CC
cord-267965-84sotgds	351	10	function	function	NN
cord-267965-84sotgds	351	11	of	of	IN
cord-267965-84sotgds	351	12	histocompatibility	histocompatibility	NN
cord-267965-84sotgds	351	13	and	and	CC
cord-267965-84sotgds	351	14	other	other	JJ
cord-267965-84sotgds	351	15	genes	gene	NNS
cord-267965-84sotgds	352	1	Appearances	appearance	NNS
cord-267965-84sotgds	352	2	can	can	MD
cord-267965-84sotgds	352	3	be	be	VB
cord-267965-84sotgds	352	4	deceiving	deceive	VBG
cord-267965-84sotgds	352	5	:	:	:
cord-267965-84sotgds	352	6	phenotypes	phenotype	NNS
cord-267965-84sotgds	352	7	of	of	IN
cord-267965-84sotgds	352	8	knockout	knockout	NN
cord-267965-84sotgds	352	9	mice	mouse	NNS
cord-267965-84sotgds	352	10	Genealogies	genealogy	NNS
cord-267965-84sotgds	352	11	of	of	IN
cord-267965-84sotgds	352	12	mouse	mouse	NN
cord-267965-84sotgds	352	13	inbred	inbreed	VBN
cord-267965-84sotgds	352	14	strains	strain	NNS
cord-267965-84sotgds	353	1	Host	host	JJ
cord-267965-84sotgds	353	2	genetic	genetic	JJ
cord-267965-84sotgds	353	3	variation	variation	NN
cord-267965-84sotgds	353	4	affects	affect	VBZ
cord-267965-84sotgds	353	5	resistance	resistance	NN
cord-267965-84sotgds	353	6	to	to	IN
cord-267965-84sotgds	353	7	infection	infection	NN
cord-267965-84sotgds	353	8	with	with	IN
cord-267965-84sotgds	353	9	a	a	DT
cord-267965-84sotgds	353	10	highly	highly	RB
cord-267965-84sotgds	353	11	pathogenic	pathogenic	JJ
cord-267965-84sotgds	353	12	H5N1	H5N1	NNP
cord-267965-84sotgds	353	13	influenza	influenza	NN
cord-267965-84sotgds	353	14	A	a	DT
cord-267965-84sotgds	353	15	virus	virus	NN
cord-267965-84sotgds	353	16	in	in	IN
cord-267965-84sotgds	353	17	mice	mouse	NNS
cord-267965-84sotgds	353	18	Expression	expression	NN
cord-267965-84sotgds	353	19	quantitative	quantitative	JJ
cord-267965-84sotgds	353	20	trait	trait	NN
cord-267965-84sotgds	353	21	Loci	Loci	NNP
cord-267965-84sotgds	353	22	for	for	IN
cord-267965-84sotgds	353	23	extreme	extreme	JJ
cord-267965-84sotgds	353	24	host	host	NN
cord-267965-84sotgds	353	25	response	response	NN
cord-267965-84sotgds	353	26	to	to	IN
cord-267965-84sotgds	353	27	influenza	influenza	VB
cord-267965-84sotgds	353	28	a	a	DT
cord-267965-84sotgds	353	29	in	in	IN
cord-267965-84sotgds	353	30	pre	pre	JJ
cord-267965-84sotgds	353	31	-	-	JJ
cord-267965-84sotgds	353	32	collaborative	collaborative	JJ
cord-267965-84sotgds	353	33	cross	cross	NN
cord-267965-84sotgds	353	34	mice	mice	NN
cord-267965-84sotgds	353	35	Gene	Gene	NNP
cord-267965-84sotgds	353	36	targeting	target	VBG
cord-267965-84sotgds	353	37	in	in	IN
cord-267965-84sotgds	353	38	mice	mouse	NNS
cord-267965-84sotgds	353	39	:	:	:
cord-267965-84sotgds	353	40	a	a	DT
cord-267965-84sotgds	353	41	review	review	NN
cord-267965-84sotgds	353	42	Mendelian	mendelian	JJ
cord-267965-84sotgds	353	43	susceptibility	susceptibility	NN
cord-267965-84sotgds	353	44	to	to	IN
cord-267965-84sotgds	353	45	mycobacterial	mycobacterial	NNP
cord-267965-84sotgds	353	46	disease	disease	NN
cord-267965-84sotgds	353	47	:	:	:
cord-267965-84sotgds	354	1	genetic	genetic	JJ
cord-267965-84sotgds	354	2	,	,	,
cord-267965-84sotgds	354	3	immunological	immunological	JJ
cord-267965-84sotgds	354	4	,	,	,
cord-267965-84sotgds	354	5	and	and	CC
cord-267965-84sotgds	354	6	clinical	clinical	JJ
cord-267965-84sotgds	354	7	features	feature	NNS
cord-267965-84sotgds	354	8	of	of	IN
cord-267965-84sotgds	354	9	inborn	inborn	JJ
cord-267965-84sotgds	354	10	errors	error	NNS
cord-267965-84sotgds	354	11	of	of	IN
cord-267965-84sotgds	354	12	IFN	IFN	NNP
cord-267965-84sotgds	354	13	-	-	HYPH
cord-267965-84sotgds	354	14	g	g	NNP
cord-267965-84sotgds	354	15	immunity	immunity	NN
cord-267965-84sotgds	354	16	Pathogen	pathogen	NN
cord-267965-84sotgds	354	17	-	-	HYPH
cord-267965-84sotgds	354	18	driven	drive	VBN
cord-267965-84sotgds	354	19	selection	selection	NN
cord-267965-84sotgds	354	20	in	in	IN
cord-267965-84sotgds	354	21	the	the	DT
cord-267965-84sotgds	354	22	human	human	JJ
cord-267965-84sotgds	354	23	genome	genome	NN
cord-267965-84sotgds	354	24	Diet	Diet	NNP
cord-267965-84sotgds	354	25	dominates	dominate	VBZ
cord-267965-84sotgds	354	26	host	host	NN
cord-267965-84sotgds	354	27	genotype	genotype	NN
cord-267965-84sotgds	354	28	in	in	IN
cord-267965-84sotgds	354	29	shaping	shape	VBG
cord-267965-84sotgds	354	30	the	the	DT
cord-267965-84sotgds	354	31	murine	murine	JJ
cord-267965-84sotgds	354	32	gut	gut	NN
cord-267965-84sotgds	354	33	microbiota	microbiota	NN
cord-267965-84sotgds	354	34	Immunity	immunity	NN
cord-267965-84sotgds	354	35	to	to	IN
cord-267965-84sotgds	354	36	microbes	microbe	NNS
cord-267965-84sotgds	354	37	:	:	:
cord-267965-84sotgds	354	38	lessons	lesson	NNS
cord-267965-84sotgds	354	39	from	from	IN
cord-267965-84sotgds	354	40	primary	primary	JJ
cord-267965-84sotgds	354	41	immunodeficiencies	immunodeficiency	NNS
cord-267965-84sotgds	354	42	Forward	Forward	NNP
cord-267965-84sotgds	354	43	genetics	genetic	NNS
cord-267965-84sotgds	354	44	of	of	IN
cord-267965-84sotgds	354	45	infectious	infectious	JJ
cord-267965-84sotgds	354	46	diseases	disease	NNS
cord-267965-84sotgds	354	47	:	:	:
cord-267965-84sotgds	354	48	immunological	immunological	JJ
cord-267965-84sotgds	354	49	impact	impact	NN
cord-267965-84sotgds	355	1	Human	human	JJ
cord-267965-84sotgds	355	2	genetic	genetic	JJ
cord-267965-84sotgds	355	3	susceptibility	susceptibility	NN
cord-267965-84sotgds	355	4	to	to	IN
cord-267965-84sotgds	355	5	infectious	infectious	JJ
cord-267965-84sotgds	355	6	disease	disease	NN
cord-267965-84sotgds	355	7	Genetic	genetic	JJ
cord-267965-84sotgds	355	8	architecture	architecture	NN
cord-267965-84sotgds	355	9	of	of	IN
cord-267965-84sotgds	355	10	group	group	NN
cord-267965-84sotgds	355	11	A	A	NNP
cord-267965-84sotgds	355	12	Streptococcal	Streptococcal	NNP
cord-267965-84sotgds	355	13	necrotizing	necrotize	VBG
cord-267965-84sotgds	355	14	soft	soft	JJ
cord-267965-84sotgds	355	15	tissue	tissue	NN
cord-267965-84sotgds	355	16	infections	infection	NNS
cord-267965-84sotgds	355	17	in	in	IN
cord-267965-84sotgds	355	18	the	the	DT
cord-267965-84sotgds	355	19	mouse	mouse	NN
cord-267965-84sotgds	356	1	Defining	define	VBG
cord-267965-84sotgds	356	2	the	the	DT
cord-267965-84sotgds	356	3	consequences	consequence	NNS
cord-267965-84sotgds	356	4	of	of	IN
cord-267965-84sotgds	356	5	genetic	genetic	JJ
cord-267965-84sotgds	356	6	variation	variation	NN
cord-267965-84sotgds	356	7	on	on	IN
cord-267965-84sotgds	356	8	a	a	DT
cord-267965-84sotgds	356	9	proteome	proteome	NN
cord-267965-84sotgds	356	10	-	-	HYPH
cord-267965-84sotgds	356	11	wide	wide	JJ
cord-267965-84sotgds	356	12	scale	scale	NN
cord-267965-84sotgds	356	13	The	the	DT
cord-267965-84sotgds	356	14	Collaborative	Collaborative	NNP
cord-267965-84sotgds	356	15	Cross	Cross	NNP
cord-267965-84sotgds	356	16	,	,	,
cord-267965-84sotgds	356	17	a	a	DT
cord-267965-84sotgds	356	18	community	community	NN
cord-267965-84sotgds	356	19	resource	resource	NN
cord-267965-84sotgds	356	20	for	for	IN
cord-267965-84sotgds	356	21	the	the	DT
cord-267965-84sotgds	356	22	genetic	genetic	JJ
cord-267965-84sotgds	356	23	analysis	analysis	NN
cord-267965-84sotgds	356	24	of	of	IN
cord-267965-84sotgds	356	25	complex	complex	JJ
cord-267965-84sotgds	356	26	traits	trait	NNS
cord-267965-84sotgds	357	1	The	the	DT
cord-267965-84sotgds	357	2	Diversity	Diversity	NNP
cord-267965-84sotgds	357	3	Outbred	Outbred	NNP
cord-267965-84sotgds	357	4	mouse	mouse	NN
cord-267965-84sotgds	357	5	population	population	NN
cord-267965-84sotgds	357	6	Gene	Gene	NNP
cord-267965-84sotgds	357	7	therapy	therapy	NN
cord-267965-84sotgds	357	8	:	:	:
cord-267965-84sotgds	357	9	progress	progress	NN
cord-267965-84sotgds	357	10	and	and	CC
cord-267965-84sotgds	357	11	predictions	prediction	NNS
cord-267965-84sotgds	357	12	Models	model	NNS
cord-267965-84sotgds	357	13	of	of	IN
cord-267965-84sotgds	357	14	infectious	infectious	JJ
cord-267965-84sotgds	357	15	diseases	disease	NNS
cord-267965-84sotgds	357	16	in	in	IN
cord-267965-84sotgds	357	17	the	the	DT
cord-267965-84sotgds	357	18	fruit	fruit	NN
cord-267965-84sotgds	357	19	fly	fly	VB
cord-267965-84sotgds	357	20	Drosophila	drosophila	JJ
cord-267965-84sotgds	357	21	melanogaster	melanogaster	NN
cord-267965-84sotgds	357	22	Influence	influence	NN
cord-267965-84sotgds	357	23	of	of	IN
cord-267965-84sotgds	357	24	genetic	genetic	JJ
cord-267965-84sotgds	357	25	background	background	NN
cord-267965-84sotgds	357	26	on	on	IN
cord-267965-84sotgds	357	27	genetically	genetically	RB
cord-267965-84sotgds	357	28	engineered	engineer	VBN
cord-267965-84sotgds	357	29	mouse	mouse	NN
cord-267965-84sotgds	357	30	phenotypes	phenotype	NNS
cord-267965-84sotgds	357	31	Genome	Genome	NNP
cord-267965-84sotgds	357	32	-	-	HYPH
cord-267965-84sotgds	357	33	wide	wide	JJ
cord-267965-84sotgds	357	34	association	association	NN
cord-267965-84sotgds	357	35	studies	study	NNS
cord-267965-84sotgds	357	36	:	:	:
cord-267965-84sotgds	358	1	inherent	inherent	JJ
cord-267965-84sotgds	358	2	limitations	limitation	NNS
cord-267965-84sotgds	358	3	and	and	CC
cord-267965-84sotgds	358	4	future	future	JJ
cord-267965-84sotgds	358	5	challenges	challenge	NNS
cord-267965-84sotgds	358	6	Genomewide	Genomewide	NNP
cord-267965-84sotgds	358	7	association	association	NN
cord-267965-84sotgds	358	8	study	study	NN
cord-267965-84sotgds	358	9	of	of	IN
cord-267965-84sotgds	358	10	spontaneous	spontaneous	JJ
cord-267965-84sotgds	358	11	resolution	resolution	NN
cord-267965-84sotgds	358	12	of	of	IN
cord-267965-84sotgds	358	13	hepatitis	hepatitis	NN
cord-267965-84sotgds	358	14	C	C	NNP
cord-267965-84sotgds	358	15	virus	virus	NN
cord-267965-84sotgds	358	16	infection	infection	NN
cord-267965-84sotgds	358	17	:	:	:
cord-267965-84sotgds	359	1	data	datum	NNS
cord-267965-84sotgds	359	2	from	from	IN
cord-267965-84sotgds	359	3	multiple	multiple	JJ
cord-267965-84sotgds	359	4	cohorts	cohort	NNS
cord-267965-84sotgds	359	5	Collaborative	Collaborative	NNP
cord-267965-84sotgds	359	6	Cross	Cross	NNP
cord-267965-84sotgds	359	7	mice	mouse	NNS
cord-267965-84sotgds	359	8	and	and	CC
cord-267965-84sotgds	359	9	their	-PRON-	PRP$
cord-267965-84sotgds	359	10	power	power	NN
cord-267965-84sotgds	359	11	to	to	TO
cord-267965-84sotgds	359	12	map	map	VB
cord-267965-84sotgds	359	13	host	host	NN
cord-267965-84sotgds	359	14	susceptibility	susceptibility	NN
cord-267965-84sotgds	359	15	to	to	IN
cord-267965-84sotgds	359	16	Aspergillus	aspergillus	NN
cord-267965-84sotgds	359	17	fumigatus	fumigatus	NN
cord-267965-84sotgds	359	18	infection	infection	NN
cord-267965-84sotgds	360	1	Genetically	genetically	RB
cord-267965-84sotgds	360	2	diverse	diverse	JJ
cord-267965-84sotgds	360	3	CC	cc	NN
cord-267965-84sotgds	360	4	-	-	HYPH
cord-267965-84sotgds	360	5	founder	founder	NN
cord-267965-84sotgds	360	6	mouse	mouse	NN
cord-267965-84sotgds	360	7	strains	strain	NNS
cord-267965-84sotgds	360	8	replicate	replicate	VBP
cord-267965-84sotgds	360	9	the	the	DT
cord-267965-84sotgds	360	10	human	human	JJ
cord-267965-84sotgds	360	11	influenza	influenza	NN
cord-267965-84sotgds	360	12	gene	gene	NN
cord-267965-84sotgds	360	13	expression	expression	NN
cord-267965-84sotgds	360	14	signature	signature	NN
cord-267965-84sotgds	360	15	Modeling	model	VBG
cord-267965-84sotgds	360	16	host	host	NN
cord-267965-84sotgds	360	17	genetic	genetic	JJ
cord-267965-84sotgds	360	18	regulation	regulation	NN
cord-267965-84sotgds	360	19	of	of	IN
cord-267965-84sotgds	360	20	influenza	influenza	NN
cord-267965-84sotgds	360	21	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	360	22	in	in	IN
cord-267965-84sotgds	360	23	the	the	DT
cord-267965-84sotgds	360	24	collaborative	collaborative	JJ
cord-267965-84sotgds	360	25	cross	cross	JJ
cord-267965-84sotgds	360	26	Quantitative	quantitative	JJ
cord-267965-84sotgds	360	27	trait	trait	NN
cord-267965-84sotgds	360	28	locus	locus	NN
cord-267965-84sotgds	360	29	mapping	mapping	NN
cord-267965-84sotgds	360	30	methods	method	NNS
cord-267965-84sotgds	360	31	for	for	IN
cord-267965-84sotgds	360	32	diversity	diversity	NN
cord-267965-84sotgds	360	33	outbred	outbred	JJ
cord-267965-84sotgds	360	34	mice	mouse	NNS
cord-267965-84sotgds	360	35	.	.	.
cord-267965-84sotgds	361	1	G3	G3	NNP
cord-267965-84sotgds	361	2	(	(	-LRB-
cord-267965-84sotgds	361	3	Bethesda	Bethesda	NNP
cord-267965-84sotgds	361	4	)	)	-RRB-
cord-267965-84sotgds	361	5	karyoploteR	karyoploteR	NNP
cord-267965-84sotgds	361	6	:	:	:
cord-267965-84sotgds	362	1	an	an	DT
cord-267965-84sotgds	362	2	R	R	NNP
cord-267965-84sotgds	362	3	/	/	SYM
cord-267965-84sotgds	362	4	Bioconductor	Bioconductor	NNP
cord-267965-84sotgds	362	5	package	package	NN
cord-267965-84sotgds	362	6	to	to	TO
cord-267965-84sotgds	362	7	plot	plot	VB
cord-267965-84sotgds	362	8	customizable	customizable	JJ
cord-267965-84sotgds	362	9	genomes	genome	NNS
cord-267965-84sotgds	362	10	displaying	display	VBG
cord-267965-84sotgds	362	11	arbitrary	arbitrary	JJ
cord-267965-84sotgds	362	12	data	datum	NNS
cord-267965-84sotgds	362	13	Genetic	genetic	JJ
cord-267965-84sotgds	362	14	diversity	diversity	NN
cord-267965-84sotgds	362	15	in	in	IN
cord-267965-84sotgds	362	16	the	the	DT
cord-267965-84sotgds	362	17	collaborative	collaborative	JJ
cord-267965-84sotgds	362	18	cross	cross	NN
cord-267965-84sotgds	362	19	model	model	NN
cord-267965-84sotgds	362	20	recapitulates	recapitulate	VBZ
cord-267965-84sotgds	362	21	human	human	JJ
cord-267965-84sotgds	362	22	West	West	NNP
cord-267965-84sotgds	362	23	Nile	Nile	NNP
cord-267965-84sotgds	362	24	virus	virus	NN
cord-267965-84sotgds	362	25	disease	disease	NN
cord-267965-84sotgds	362	26	outcomes	outcome	NNS
cord-267965-84sotgds	363	1	A	a	DT
cord-267965-84sotgds	363	2	mouse	mouse	NN
cord-267965-84sotgds	363	3	model	model	NN
cord-267965-84sotgds	363	4	of	of	IN
cord-267965-84sotgds	363	5	chronic	chronic	JJ
cord-267965-84sotgds	363	6	West	West	NNP
cord-267965-84sotgds	363	7	Nile	Nile	NNP
cord-267965-84sotgds	363	8	virus	virus	NN
cord-267965-84sotgds	363	9	disease	disease	NN
cord-267965-84sotgds	363	10	Extensive	Extensive	NNP
cord-267965-84sotgds	363	11	homeostatic	homeostatic	JJ
cord-267965-84sotgds	363	12	T	t	NN
cord-267965-84sotgds	363	13	cell	cell	NN
cord-267965-84sotgds	363	14	phenotypic	phenotypic	NN
cord-267965-84sotgds	363	15	variation	variation	NN
cord-267965-84sotgds	363	16	within	within	IN
cord-267965-84sotgds	363	17	the	the	DT
cord-267965-84sotgds	363	18	Collaborative	Collaborative	NNP
cord-267965-84sotgds	363	19	Cross	Cross	NNP
cord-267965-84sotgds	363	20	Genome	Genome	NNP
cord-267965-84sotgds	363	21	wide	wide	JJ
cord-267965-84sotgds	363	22	identification	identification	NN
cord-267965-84sotgds	363	23	of	of	IN
cord-267965-84sotgds	363	24	SARS	SARS	NNP
cord-267965-84sotgds	363	25	-	-	HYPH
cord-267965-84sotgds	363	26	CoV	CoV	NNP
cord-267965-84sotgds	363	27	susceptibility	susceptibility	NN
cord-267965-84sotgds	363	28	loci	locus	NNS
cord-267965-84sotgds	363	29	using	use	VBG
cord-267965-84sotgds	363	30	the	the	DT
cord-267965-84sotgds	363	31	Collaborative	Collaborative	NNP
cord-267965-84sotgds	363	32	Cross	Cross	NNP
cord-267965-84sotgds	363	33	Allelic	Allelic	NNP
cord-267965-84sotgds	363	34	variation	variation	NN
cord-267965-84sotgds	363	35	in	in	IN
cord-267965-84sotgds	363	36	the	the	DT
cord-267965-84sotgds	363	37	Toll	Toll	NNP
cord-267965-84sotgds	363	38	-	-	HYPH
cord-267965-84sotgds	363	39	like	like	JJ
cord-267965-84sotgds	363	40	receptor	receptor	NN
cord-267965-84sotgds	363	41	adaptor	adaptor	NN
cord-267965-84sotgds	363	42	protein	protein	NN
cord-267965-84sotgds	364	1	Ticam2	Ticam2	NNP
cord-267965-84sotgds	364	2	contributes	contribute	VBZ
cord-267965-84sotgds	364	3	to	to	IN
cord-267965-84sotgds	364	4	SARS	SARS	NNP
cord-267965-84sotgds	364	5	-	-	HYPH
cord-267965-84sotgds	364	6	coronavirus	coronavirus	NN
cord-267965-84sotgds	364	7	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	364	8	in	in	IN
cord-267965-84sotgds	364	9	mice	mouse	NNS
cord-267965-84sotgds	364	10	Oas1b	oas1b	JJ
cord-267965-84sotgds	364	11	-	-	HYPH
cord-267965-84sotgds	364	12	dependent	dependent	JJ
cord-267965-84sotgds	364	13	immune	immune	JJ
cord-267965-84sotgds	364	14	transcriptional	transcriptional	JJ
cord-267965-84sotgds	364	15	profiles	profile	NNS
cord-267965-84sotgds	364	16	of	of	IN
cord-267965-84sotgds	364	17	West	West	NNP
cord-267965-84sotgds	364	18	Nile	Nile	NNP
cord-267965-84sotgds	364	19	virus	virus	NN
cord-267965-84sotgds	364	20	infection	infection	NN
cord-267965-84sotgds	364	21	in	in	IN
cord-267965-84sotgds	364	22	the	the	DT
cord-267965-84sotgds	364	23	Collaborative	Collaborative	NNP
cord-267965-84sotgds	364	24	Cross	Cross	NNP
cord-267965-84sotgds	364	25	.	.	.
cord-267965-84sotgds	365	1	G3	G3	NNP
cord-267965-84sotgds	366	1	(	(	-LRB-
cord-267965-84sotgds	366	2	Bethesda	Bethesda	NNP
cord-267965-84sotgds	366	3	)	)	-RRB-
cord-267965-84sotgds	366	4	Population	population	NN
cord-267965-84sotgds	366	5	genetics	genetic	NNS
cord-267965-84sotgds	366	6	of	of	IN
cord-267965-84sotgds	366	7	malaria	malaria	NN
cord-267965-84sotgds	366	8	resistance	resistance	NN
cord-267965-84sotgds	366	9	in	in	IN
cord-267965-84sotgds	366	10	humans	human	NNS
cord-267965-84sotgds	366	11	Evolution	Evolution	NNP
cord-267965-84sotgds	366	12	,	,	,
cord-267965-84sotgds	366	13	revolution	revolution	NN
cord-267965-84sotgds	366	14	and	and	CC
cord-267965-84sotgds	366	15	heresy	heresy	NN
cord-267965-84sotgds	366	16	in	in	IN
cord-267965-84sotgds	366	17	the	the	DT
cord-267965-84sotgds	366	18	genetics	genetic	NNS
cord-267965-84sotgds	366	19	of	of	IN
cord-267965-84sotgds	366	20	infectious	infectious	JJ
cord-267965-84sotgds	366	21	disease	disease	NN
cord-267965-84sotgds	366	22	susceptibility	susceptibility	NN
cord-267965-84sotgds	366	23	Susceptibility	Susceptibility	NNP
cord-267965-84sotgds	366	24	of	of	IN
cord-267965-84sotgds	366	25	CXB	CXB	NNP
cord-267965-84sotgds	366	26	recombinant	recombinant	JJ
cord-267965-84sotgds	366	27	inbred	inbred	JJ
cord-267965-84sotgds	366	28	mice	mouse	NNS
cord-267965-84sotgds	366	29	to	to	IN
cord-267965-84sotgds	366	30	murine	murine	JJ
cord-267965-84sotgds	366	31	plasmodia	plasmodia	NNP
cord-267965-84sotgds	367	1	The	the	DT
cord-267965-84sotgds	367	2	genome	genome	NN
cord-267965-84sotgds	367	3	architecture	architecture	NN
cord-267965-84sotgds	367	4	of	of	IN
cord-267965-84sotgds	367	5	the	the	DT
cord-267965-84sotgds	367	6	Collaborative	Collaborative	NNP
cord-267965-84sotgds	367	7	Cross	Cross	NNP
cord-267965-84sotgds	367	8	mouse	mouse	NN
cord-267965-84sotgds	367	9	genetic	genetic	JJ
cord-267965-84sotgds	367	10	reference	reference	NN
cord-267965-84sotgds	367	11	population	population	NN
cord-267965-84sotgds	367	12	Twin	Twin	NNP
cord-267965-84sotgds	367	13	studies	study	NNS
cord-267965-84sotgds	367	14	on	on	IN
cord-267965-84sotgds	367	15	genetic	genetic	JJ
cord-267965-84sotgds	367	16	variations	variation	NNS
cord-267965-84sotgds	367	17	in	in	IN
cord-267965-84sotgds	367	18	resistance	resistance	NN
cord-267965-84sotgds	367	19	to	to	IN
cord-267965-84sotgds	367	20	tuberculosis	tuberculosis	NN
cord-267965-84sotgds	367	21	Of	of	IN
cord-267965-84sotgds	367	22	mice	mouse	NNS
cord-267965-84sotgds	367	23	and	and	CC
cord-267965-84sotgds	367	24	men	man	NNS
cord-267965-84sotgds	367	25	:	:	:
cord-267965-84sotgds	367	26	the	the	DT
cord-267965-84sotgds	367	27	host	host	NN
cord-267965-84sotgds	367	28	response	response	NN
cord-267965-84sotgds	367	29	to	to	IN
cord-267965-84sotgds	367	30	influenza	influenza	NN
cord-267965-84sotgds	367	31	virus	virus	NN
cord-267965-84sotgds	367	32	infection	infection	NN
cord-267965-84sotgds	367	33	Profiling	profiling	NN
cord-267965-84sotgds	367	34	and	and	CC
cord-267965-84sotgds	367	35	genetic	genetic	JJ
cord-267965-84sotgds	367	36	control	control	NN
cord-267965-84sotgds	367	37	of	of	IN
cord-267965-84sotgds	367	38	the	the	DT
cord-267965-84sotgds	367	39	murine	murine	JJ
cord-267965-84sotgds	367	40	immunoglobulin	immunoglobulin	NN
cord-267965-84sotgds	367	41	G	g	NN
cord-267965-84sotgds	367	42	glycome	glycome	NN
cord-267965-84sotgds	367	43	Influenza	influenza	NN
cord-267965-84sotgds	367	44	H3N2	H3N2	NNP
cord-267965-84sotgds	367	45	infection	infection	NN
cord-267965-84sotgds	367	46	of	of	IN
cord-267965-84sotgds	367	47	the	the	DT
cord-267965-84sotgds	367	48	collaborative	collaborative	NNP
cord-267965-84sotgds	367	49	cross	cross	NN
cord-267965-84sotgds	367	50	founder	founder	NN
cord-267965-84sotgds	367	51	strains	strain	NNS
cord-267965-84sotgds	367	52	reveals	reveal	VBZ
cord-267965-84sotgds	367	53	highly	highly	RB
cord-267965-84sotgds	367	54	divergent	divergent	JJ
cord-267965-84sotgds	367	55	host	host	NN
cord-267965-84sotgds	367	56	responses	response	NNS
cord-267965-84sotgds	367	57	and	and	CC
cord-267965-84sotgds	367	58	identifies	identify	VBZ
cord-267965-84sotgds	367	59	a	a	DT
cord-267965-84sotgds	367	60	unique	unique	JJ
cord-267965-84sotgds	367	61	phenotype	phenotype	NN
cord-267965-84sotgds	367	62	in	in	IN
cord-267965-84sotgds	367	63	CAST	cast	NN
cord-267965-84sotgds	367	64	/	/	SYM
cord-267965-84sotgds	367	65	EiJ	eij	NN
cord-267965-84sotgds	367	66	mice	mice	NN
cord-267965-84sotgds	367	67	Genomics	genomic	NNS
cord-267965-84sotgds	367	68	of	of	IN
cord-267965-84sotgds	367	69	immune	immune	JJ
cord-267965-84sotgds	367	70	diseases	disease	NNS
cord-267965-84sotgds	367	71	and	and	CC
cord-267965-84sotgds	367	72	new	new	JJ
cord-267965-84sotgds	367	73	therapies	therapy	NNS
cord-267965-84sotgds	368	1	Host	host	JJ
cord-267965-84sotgds	368	2	genetic	genetic	JJ
cord-267965-84sotgds	368	3	determinants	determinant	NNS
cord-267965-84sotgds	368	4	of	of	IN
cord-267965-84sotgds	368	5	influenza	influenza	NN
cord-267965-84sotgds	368	6	pathogenicity	pathogenicity	NN
cord-267965-84sotgds	368	7	Host	Host	NNP
cord-267965-84sotgds	368	8	genetic	genetic	JJ
cord-267965-84sotgds	368	9	diversity	diversity	NN
cord-267965-84sotgds	368	10	influences	influence	VBZ
cord-267965-84sotgds	368	11	the	the	DT
cord-267965-84sotgds	368	12	severity	severity	NN
cord-267965-84sotgds	368	13	of	of	IN
cord-267965-84sotgds	368	14	Pseudomonas	Pseudomonas	NNP
cord-267965-84sotgds	368	15	aeruginosa	aeruginosa	NN
cord-267965-84sotgds	368	16	pneumonia	pneumonia	NN
cord-267965-84sotgds	368	17	in	in	IN
cord-267965-84sotgds	368	18	the	the	DT
cord-267965-84sotgds	368	19	Collaborative	Collaborative	NNP
cord-267965-84sotgds	368	20	Cross	Cross	NNP
cord-267965-84sotgds	368	21	mice	mouse	NNS
cord-267965-84sotgds	368	22	Protection	Protection	NNP
cord-267965-84sotgds	368	23	by	by	IN
cord-267965-84sotgds	368	24	BCG	BCG	NNP
cord-267965-84sotgds	368	25	vaccine	vaccine	NN
cord-267965-84sotgds	368	26	against	against	IN
cord-267965-84sotgds	368	27	tuberculosis	tuberculosis	NN
cord-267965-84sotgds	368	28	:	:	:
cord-267965-84sotgds	368	29	a	a	DT
cord-267965-84sotgds	368	30	systematic	systematic	JJ
cord-267965-84sotgds	368	31	review	review	NN
cord-267965-84sotgds	368	32	of	of	IN
cord-267965-84sotgds	368	33	randomized	randomized	JJ
cord-267965-84sotgds	368	34	controlled	control	VBN
cord-267965-84sotgds	368	35	trials	trial	NNS
cord-267965-84sotgds	368	36	Caenorhabditis	Caenorhabditis	NNP
cord-267965-84sotgds	368	37	elegans	elegan	NNS
cord-267965-84sotgds	368	38	,	,	,
cord-267965-84sotgds	368	39	a	a	DT
cord-267965-84sotgds	368	40	model	model	NN
cord-267965-84sotgds	368	41	organism	organism	NN
cord-267965-84sotgds	368	42	for	for	IN
cord-267965-84sotgds	368	43	investigating	investigate	VBG
cord-267965-84sotgds	368	44	immunity	immunity	NN
cord-267965-84sotgds	368	45	Of	of	IN
cord-267965-84sotgds	368	46	mice	mouse	NNS
cord-267965-84sotgds	368	47	,	,	,
cord-267965-84sotgds	368	48	dirty	dirty	JJ
cord-267965-84sotgds	368	49	mice	mouse	NNS
cord-267965-84sotgds	368	50	,	,	,
cord-267965-84sotgds	368	51	and	and	CC
cord-267965-84sotgds	368	52	men	man	NNS
cord-267965-84sotgds	368	53	:	:	:
cord-267965-84sotgds	368	54	using	use	VBG
cord-267965-84sotgds	368	55	mice	mouse	NNS
cord-267965-84sotgds	368	56	to	to	TO
cord-267965-84sotgds	368	57	understand	understand	VB
cord-267965-84sotgds	368	58	human	human	JJ
cord-267965-84sotgds	368	59	immunology	immunology	NN
cord-267965-84sotgds	368	60	Architecture	Architecture	NNP
cord-267965-84sotgds	368	61	of	of	IN
cord-267965-84sotgds	368	62	energy	energy	NN
cord-267965-84sotgds	368	63	balance	balance	NN
cord-267965-84sotgds	368	64	traits	trait	NNS
cord-267965-84sotgds	368	65	in	in	IN
cord-267965-84sotgds	368	66	emerging	emerge	VBG
cord-267965-84sotgds	368	67	lines	line	NNS
cord-267965-84sotgds	368	68	of	of	IN
cord-267965-84sotgds	368	69	the	the	DT
cord-267965-84sotgds	368	70	Collaborative	Collaborative	NNP
cord-267965-84sotgds	368	71	Cross	Cross	NNP
cord-267965-84sotgds	368	72	Bayesian	Bayesian	NNP
cord-267965-84sotgds	368	73	diallel	diallel	NNS
cord-267965-84sotgds	368	74	analysis	analysis	NN
cord-267965-84sotgds	368	75	reveals	reveal	VBZ
cord-267965-84sotgds	368	76	Mx1-dependent	Mx1-dependent	NNP
cord-267965-84sotgds	368	77	and	and	CC
cord-267965-84sotgds	368	78	Mx1-independent	Mx1-independent	NNP
cord-267965-84sotgds	368	79	effects	effect	NNS
cord-267965-84sotgds	368	80	on	on	IN
cord-267965-84sotgds	368	81	response	response	NN
cord-267965-84sotgds	368	82	to	to	TO
cord-267965-84sotgds	368	83	influenza	influenza	VB
cord-267965-84sotgds	368	84	A	a	DT
cord-267965-84sotgds	368	85	virus	virus	NN
cord-267965-84sotgds	368	86	in	in	IN
cord-267965-84sotgds	368	87	mice	mouse	NNS
cord-267965-84sotgds	369	1	A	a	DT
cord-267965-84sotgds	369	2	novel	novel	JJ
cord-267965-84sotgds	369	3	outbred	outbred	JJ
cord-267965-84sotgds	369	4	mouse	mouse	NN
cord-267965-84sotgds	369	5	model	model	NN
cord-267965-84sotgds	369	6	of	of	IN
cord-267965-84sotgds	369	7	2009	2009	CD
cord-267965-84sotgds	369	8	pandemic	pandemic	NN
cord-267965-84sotgds	369	9	influenza	influenza	NN
cord-267965-84sotgds	369	10	and	and	CC
cord-267965-84sotgds	369	11	bacterial	bacterial	JJ
cord-267965-84sotgds	369	12	coinfection	coinfection	NN
cord-267965-84sotgds	369	13	severity	severity	NN
cord-267965-84sotgds	369	14	Polymorphisms	polymorphism	NNS
cord-267965-84sotgds	369	15	of	of	IN
cord-267965-84sotgds	369	16	large	large	JJ
cord-267965-84sotgds	369	17	effect	effect	NN
cord-267965-84sotgds	369	18	explain	explain	VBP
cord-267965-84sotgds	369	19	the	the	DT
cord-267965-84sotgds	369	20	majority	majority	NN
cord-267965-84sotgds	369	21	of	of	IN
cord-267965-84sotgds	369	22	the	the	DT
cord-267965-84sotgds	369	23	host	host	NN
cord-267965-84sotgds	369	24	genetic	genetic	JJ
cord-267965-84sotgds	369	25	contribution	contribution	NN
cord-267965-84sotgds	369	26	to	to	IN
cord-267965-84sotgds	369	27	variation	variation	NN
cord-267965-84sotgds	369	28	of	of	IN
cord-267965-84sotgds	369	29	HIV-1	HIV-1	NNP
cord-267965-84sotgds	369	30	virus	virus	NN
cord-267965-84sotgds	369	31	load	load	NN
cord-267965-84sotgds	369	32	The	the	DT
cord-267965-84sotgds	369	33	International	International	NNP
cord-267965-84sotgds	369	34	Mouse	Mouse	NNP
cord-267965-84sotgds	369	35	Phenotyping	Phenotyping	NNP
cord-267965-84sotgds	369	36	Consortium	Consortium	NNP
cord-267965-84sotgds	369	37	(	(	-LRB-
cord-267965-84sotgds	369	38	IMPC	IMPC	NNP
cord-267965-84sotgds	369	39	)	)	-RRB-
cord-267965-84sotgds	369	40	:	:	:
cord-267965-84sotgds	369	41	a	a	DT
cord-267965-84sotgds	369	42	functional	functional	JJ
cord-267965-84sotgds	369	43	catalogue	catalogue	NN
cord-267965-84sotgds	369	44	of	of	IN
cord-267965-84sotgds	369	45	the	the	DT
cord-267965-84sotgds	369	46	mammalian	mammalian	JJ
cord-267965-84sotgds	369	47	genome	genome	NN
cord-267965-84sotgds	369	48	that	that	WDT
cord-267965-84sotgds	369	49	informs	inform	VBZ
cord-267965-84sotgds	369	50	conservation	conservation	NN
cord-267965-84sotgds	369	51	Distinct	distinct	JJ
cord-267965-84sotgds	369	52	gene	gene	NN
cord-267965-84sotgds	369	53	loci	locus	NNS
cord-267965-84sotgds	369	54	control	control	VBP
cord-267965-84sotgds	369	55	the	the	DT
cord-267965-84sotgds	369	56	host	host	NN
cord-267965-84sotgds	369	57	response	response	NN
cord-267965-84sotgds	369	58	to	to	IN
cord-267965-84sotgds	369	59	influenza	influenza	NN
cord-267965-84sotgds	369	60	H1N1	H1N1	NNP
cord-267965-84sotgds	369	61	virus	virus	NN
cord-267965-84sotgds	369	62	infection	infection	NN
cord-267965-84sotgds	369	63	in	in	IN
cord-267965-84sotgds	369	64	a	a	DT
cord-267965-84sotgds	369	65	time	time	NN
cord-267965-84sotgds	369	66	-	-	HYPH
cord-267965-84sotgds	369	67	dependent	dependent	JJ
cord-267965-84sotgds	369	68	manner	manner	NN
cord-267965-84sotgds	369	69	Genome	genome	NN
cord-267965-84sotgds	369	70	-	-	HYPH
cord-267965-84sotgds	369	71	wide	wide	JJ
cord-267965-84sotgds	369	72	association	association	NN
cord-267965-84sotgds	369	73	studies	study	NNS
cord-267965-84sotgds	369	74	and	and	CC
cord-267965-84sotgds	369	75	susceptibility	susceptibility	NN
cord-267965-84sotgds	369	76	to	to	IN
cord-267965-84sotgds	369	77	infectious	infectious	JJ
cord-267965-84sotgds	369	78	diseases	disease	NNS
cord-267965-84sotgds	370	1	Lung	lung	NN
cord-267965-84sotgds	370	2	necrosis	necrosis	NN
cord-267965-84sotgds	370	3	and	and	CC
cord-267965-84sotgds	370	4	neutrophils	neutrophil	NNS
cord-267965-84sotgds	370	5	reflect	reflect	VBP
cord-267965-84sotgds	370	6	common	common	JJ
cord-267965-84sotgds	370	7	pathways	pathway	NNS
cord-267965-84sotgds	370	8	of	of	IN
cord-267965-84sotgds	370	9	susceptibility	susceptibility	NN
cord-267965-84sotgds	370	10	to	to	IN
cord-267965-84sotgds	370	11	Mycobacterium	Mycobacterium	NNP
cord-267965-84sotgds	370	12	tuberculosis	tuberculosis	NN
cord-267965-84sotgds	370	13	in	in	IN
cord-267965-84sotgds	370	14	genetically	genetically	RB
cord-267965-84sotgds	370	15	diverse	diverse	JJ
cord-267965-84sotgds	370	16	,	,	,
cord-267965-84sotgds	370	17	immune	immune	JJ
cord-267965-84sotgds	370	18	-	-	HYPH
cord-267965-84sotgds	370	19	competent	competent	JJ
cord-267965-84sotgds	370	20	mice	mouse	NNS
cord-267965-84sotgds	371	1	Knockout	knockout	NN
cord-267965-84sotgds	371	2	mouse	mouse	NN
cord-267965-84sotgds	371	3	fact	fact	NN
cord-267965-84sotgds	371	4	sheet	sheet	NN
cord-267965-84sotgds	371	5	Differences	difference	NNS
cord-267965-84sotgds	371	6	in	in	IN
cord-267965-84sotgds	371	7	the	the	DT
cord-267965-84sotgds	371	8	immune	immune	JJ
cord-267965-84sotgds	371	9	response	response	NN
cord-267965-84sotgds	371	10	during	during	IN
cord-267965-84sotgds	371	11	the	the	DT
cord-267965-84sotgds	371	12	acute	acute	JJ
cord-267965-84sotgds	371	13	phase	phase	NN
cord-267965-84sotgds	371	14	of	of	IN
cord-267965-84sotgds	371	15	E-55	E-55	NNP
cord-267965-84sotgds	371	16	+	+	CC
cord-267965-84sotgds	371	17	murine	murine	JJ
cord-267965-84sotgds	371	18	leukemia	leukemia	NN
cord-267965-84sotgds	371	19	virus	virus	NN
cord-267965-84sotgds	371	20	infection	infection	NN
cord-267965-84sotgds	371	21	in	in	IN
cord-267965-84sotgds	371	22	progressor	progressor	NNP
cord-267965-84sotgds	371	23	BALB	BALB	NNP
cord-267965-84sotgds	371	24	and	and	CC
cord-267965-84sotgds	372	1	long	long	JJ
cord-267965-84sotgds	372	2	term	term	NN
cord-267965-84sotgds	372	3	nonprogressor	nonprogressor	NNP
cord-267965-84sotgds	372	4	C57BL	c57bl	NN
cord-267965-84sotgds	372	5	mice	mouse	NNS
cord-267965-84sotgds	372	6	A	a	DT
cord-267965-84sotgds	372	7	new	new	JJ
cord-267965-84sotgds	372	8	set	set	NN
cord-267965-84sotgds	372	9	of	of	IN
cord-267965-84sotgds	372	10	BXD	BXD	NNP
cord-267965-84sotgds	372	11	recombinant	recombinant	JJ
cord-267965-84sotgds	372	12	inbred	inbred	JJ
cord-267965-84sotgds	372	13	lines	line	NNS
cord-267965-84sotgds	372	14	from	from	IN
cord-267965-84sotgds	372	15	advanced	advanced	JJ
cord-267965-84sotgds	372	16	intercross	intercross	NNP
cord-267965-84sotgds	372	17	populations	population	NNS
cord-267965-84sotgds	372	18	in	in	IN
cord-267965-84sotgds	372	19	mice	mouse	NNS
cord-267965-84sotgds	372	20	Mouse	Mouse	NNP
cord-267965-84sotgds	372	21	genome	genome	NN
cord-267965-84sotgds	372	22	engineering	engineering	NN
cord-267965-84sotgds	372	23	via	via	IN
cord-267965-84sotgds	372	24	CRISPR	CRISPR	NNP
cord-267965-84sotgds	372	25	-	-	HYPH
cord-267965-84sotgds	372	26	Cas9	Cas9	NNP
cord-267965-84sotgds	372	27	for	for	IN
cord-267965-84sotgds	372	28	study	study	NN
cord-267965-84sotgds	372	29	of	of	IN
cord-267965-84sotgds	372	30	immune	immune	JJ
cord-267965-84sotgds	372	31	function	function	NN
cord-267965-84sotgds	372	32	Positional	Positional	NNP
cord-267965-84sotgds	372	33	cloning	cloning	NN
cord-267965-84sotgds	372	34	of	of	IN
cord-267965-84sotgds	372	35	the	the	DT
cord-267965-84sotgds	372	36	murine	murine	JJ
cord-267965-84sotgds	372	37	flavivirus	flavivirus	JJ
cord-267965-84sotgds	372	38	resistance	resistance	NN
cord-267965-84sotgds	372	39	gene	gene	NN
cord-267965-84sotgds	372	40	Using	use	VBG
cord-267965-84sotgds	372	41	the	the	DT
cord-267965-84sotgds	372	42	emerging	emerge	VBG
cord-267965-84sotgds	372	43	Collaborative	Collaborative	NNP
cord-267965-84sotgds	372	44	Cross	Cross	NNP
cord-267965-84sotgds	372	45	to	to	TO
cord-267965-84sotgds	372	46	probe	probe	VB
cord-267965-84sotgds	372	47	the	the	DT
cord-267965-84sotgds	372	48	immune	immune	JJ
cord-267965-84sotgds	372	49	system	system	NN
cord-267965-84sotgds	372	50	International	International	NNP
cord-267965-84sotgds	372	51	Union	Union	NNP
cord-267965-84sotgds	372	52	of	of	IN
cord-267965-84sotgds	372	53	Immunological	Immunological	NNP
cord-267965-84sotgds	372	54	Societies	Societies	NNPS
cord-267965-84sotgds	372	55	:	:	:
cord-267965-84sotgds	373	1	2017	2017	CD
cord-267965-84sotgds	373	2	Primary	Primary	NNP
cord-267965-84sotgds	373	3	Immunodeficiency	Immunodeficiency	NNP
cord-267965-84sotgds	373	4	Diseases	Diseases	NNPS
cord-267965-84sotgds	373	5	Committee	Committee	NNP
cord-267965-84sotgds	373	6	Report	Report	NNP
cord-267965-84sotgds	373	7	on	on	IN
cord-267965-84sotgds	373	8	Inborn	Inborn	NNP
cord-267965-84sotgds	373	9	Errors	error	NNS
cord-267965-84sotgds	373	10	of	of	IN
cord-267965-84sotgds	373	11	Immunity	Immunity	NNP
cord-267965-84sotgds	373	12	HIV-1-resistance	hiv-1-resistance	NN
cord-267965-84sotgds	373	13	phenotype	phenotype	NN
cord-267965-84sotgds	373	14	conferred	confer	VBN
cord-267965-84sotgds	373	15	by	by	IN
cord-267965-84sotgds	373	16	combination	combination	NN
cord-267965-84sotgds	373	17	of	of	IN
cord-267965-84sotgds	373	18	two	two	CD
cord-267965-84sotgds	373	19	separate	separate	JJ
cord-267965-84sotgds	373	20	inherited	inherit	VBN
cord-267965-84sotgds	373	21	mutations	mutation	NNS
cord-267965-84sotgds	373	22	of	of	IN
cord-267965-84sotgds	373	23	CCR5	CCR5	NNP
cord-267965-84sotgds	373	24	gene	gene	NN
cord-267965-84sotgds	373	25	Endotoxin	endotoxin	NN
cord-267965-84sotgds	373	26	-	-	HYPH
cord-267965-84sotgds	373	27	tolerant	tolerant	JJ
cord-267965-84sotgds	373	28	mice	mouse	NNS
cord-267965-84sotgds	373	29	have	have	VBP
cord-267965-84sotgds	373	30	mutations	mutation	NNS
cord-267965-84sotgds	373	31	in	in	IN
cord-267965-84sotgds	373	32	Toll	Toll	NNP
cord-267965-84sotgds	373	33	-	-	HYPH
cord-267965-84sotgds	373	34	like	like	JJ
cord-267965-84sotgds	373	35	receptor	receptor	NN
cord-267965-84sotgds	373	36	4	4	CD
cord-267965-84sotgds	374	1	(	(	-LRB-
cord-267965-84sotgds	374	2	Tlr4	Tlr4	NNP
cord-267965-84sotgds	374	3	)	)	-RRB-
cord-267965-84sotgds	374	4	Host	host	JJ
cord-267965-84sotgds	374	5	genetic	genetic	JJ
cord-267965-84sotgds	374	6	diversity	diversity	NN
cord-267965-84sotgds	374	7	enables	enable	VBZ
cord-267965-84sotgds	374	8	Ebola	Ebola	NNP
cord-267965-84sotgds	374	9	hemorrhagic	hemorrhagic	JJ
cord-267965-84sotgds	374	10	fever	fever	NN
cord-267965-84sotgds	374	11	pathogenesis	pathogenesis	NN
cord-267965-84sotgds	374	12	and	and	CC
cord-267965-84sotgds	374	13	resistance	resistance	NN
cord-267965-84sotgds	375	1	The	the	DT
cord-267965-84sotgds	375	2	polymorphism	polymorphism	NN
cord-267965-84sotgds	375	3	architecture	architecture	NN
cord-267965-84sotgds	375	4	of	of	IN
cord-267965-84sotgds	375	5	mouse	mouse	NN
cord-267965-84sotgds	375	6	genetic	genetic	JJ
cord-267965-84sotgds	375	7	resources	resource	NNS
cord-267965-84sotgds	375	8	elucidated	elucidate	VBN
cord-267965-84sotgds	375	9	using	use	VBG
cord-267965-84sotgds	375	10	genome	genome	NN
cord-267965-84sotgds	375	11	-	-	HYPH
cord-267965-84sotgds	375	12	wide	wide	JJ
cord-267965-84sotgds	375	13	resequencing	resequencing	NN
cord-267965-84sotgds	375	14	data	datum	NNS
cord-267965-84sotgds	375	15	:	:	:
cord-267965-84sotgds	375	16	implications	implication	NNS
cord-267965-84sotgds	375	17	for	for	IN
cord-267965-84sotgds	375	18	QTL	QTL	NNP
cord-267965-84sotgds	375	19	discovery	discovery	NN
cord-267965-84sotgds	375	20	and	and	CC
cord-267965-84sotgds	375	21	systems	system	NNS
cord-267965-84sotgds	375	22	genetics	genetic	NNS
cord-267965-84sotgds	376	1	The	the	DT
cord-267965-84sotgds	376	2	Collaborative	Collaborative	NNP
cord-267965-84sotgds	376	3	Cross	Cross	NNP
cord-267965-84sotgds	376	4	as	as	IN
cord-267965-84sotgds	376	5	a	a	DT
cord-267965-84sotgds	376	6	resource	resource	NN
cord-267965-84sotgds	376	7	for	for	IN
cord-267965-84sotgds	376	8	modeling	model	VBG
cord-267965-84sotgds	376	9	human	human	JJ
cord-267965-84sotgds	376	10	disease	disease	NN
cord-267965-84sotgds	376	11	:	:	:
cord-267965-84sotgds	377	1	CC011	CC011	NNP
cord-267965-84sotgds	377	2	/	/	SYM
cord-267965-84sotgds	377	3	Unc	Unc	NNP
cord-267965-84sotgds	377	4	,	,	,
cord-267965-84sotgds	377	5	a	a	DT
cord-267965-84sotgds	377	6	new	new	JJ
cord-267965-84sotgds	377	7	mouse	mouse	NN
cord-267965-84sotgds	377	8	model	model	NN
cord-267965-84sotgds	377	9	for	for	IN
cord-267965-84sotgds	377	10	spontaneous	spontaneous	JJ
cord-267965-84sotgds	377	11	colitis	colitis	NN
cord-267965-84sotgds	377	12	Complexity	complexity	NN
cord-267965-84sotgds	377	13	in	in	IN
cord-267965-84sotgds	377	14	the	the	DT
cord-267965-84sotgds	377	15	host	host	NN
cord-267965-84sotgds	377	16	response	response	NN
cord-267965-84sotgds	377	17	to	to	IN
cord-267965-84sotgds	377	18	Salmonella	Salmonella	NNP
cord-267965-84sotgds	377	19	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	377	20	infection	infection	NN
cord-267965-84sotgds	377	21	in	in	IN
cord-267965-84sotgds	377	22	AcB	acb	NN
cord-267965-84sotgds	377	23	and	and	CC
cord-267965-84sotgds	377	24	BcA	bca	NN
cord-267965-84sotgds	377	25	recombinant	recombinant	JJ
cord-267965-84sotgds	377	26	congenic	congenic	NNP
cord-267965-84sotgds	377	27	strains	strain	NNS
cord-267965-84sotgds	378	1	Perinatal	perinatal	JJ
cord-267965-84sotgds	378	2	nutrition	nutrition	NN
cord-267965-84sotgds	378	3	interacts	interact	VBZ
cord-267965-84sotgds	378	4	with	with	IN
cord-267965-84sotgds	378	5	genetic	genetic	JJ
cord-267965-84sotgds	378	6	background	background	NN
cord-267965-84sotgds	378	7	to	to	TO
cord-267965-84sotgds	378	8	alter	alter	VB
cord-267965-84sotgds	378	9	behavior	behavior	NN
cord-267965-84sotgds	378	10	in	in	IN
cord-267965-84sotgds	378	11	a	a	DT
cord-267965-84sotgds	378	12	parentof	parentof	JJ
cord-267965-84sotgds	378	13	-	-	HYPH
cord-267965-84sotgds	378	14	origin	origin	NN
cord-267965-84sotgds	378	15	-	-	HYPH
cord-267965-84sotgds	378	16	dependent	dependent	JJ
cord-267965-84sotgds	378	17	manner	manner	NN
cord-267965-84sotgds	378	18	in	in	IN
cord-267965-84sotgds	378	19	adult	adult	NN
cord-267965-84sotgds	378	20	Collaborative	Collaborative	NNP
cord-267965-84sotgds	378	21	Cross	Cross	NNP
cord-267965-84sotgds	378	22	mice	mice	NN
cord-267965-84sotgds	378	23	Mapping	mapping	NN
cord-267965-84sotgds	378	24	of	of	IN
cord-267965-84sotgds	378	25	genetic	genetic	JJ
cord-267965-84sotgds	378	26	modulators	modulator	NNS
cord-267965-84sotgds	378	27	of	of	IN
cord-267965-84sotgds	378	28	natural	natural	JJ
cord-267965-84sotgds	378	29	resistance	resistance	NN
cord-267965-84sotgds	378	30	to	to	IN
cord-267965-84sotgds	378	31	infection	infection	NN
cord-267965-84sotgds	378	32	with	with	IN
cord-267965-84sotgds	378	33	Salmonella	Salmonella	NNP
cord-267965-84sotgds	378	34	typhimurium	typhimurium	NN
cord-267965-84sotgds	378	35	in	in	IN
cord-267965-84sotgds	378	36	wild	wild	NN
cord-267965-84sotgds	378	37	-	-	HYPH
cord-267965-84sotgds	378	38	derived	derive	VBN
cord-267965-84sotgds	378	39	mice	mice	NN
cord-267965-84sotgds	379	1	Genomic	genomic	JJ
cord-267965-84sotgds	379	2	responses	response	NNS
cord-267965-84sotgds	379	3	in	in	IN
cord-267965-84sotgds	379	4	mouse	mouse	NN
cord-267965-84sotgds	379	5	models	model	NNS
cord-267965-84sotgds	379	6	poorly	poorly	RB
cord-267965-84sotgds	379	7	mimic	mimic	VBP
cord-267965-84sotgds	379	8	human	human	JJ
cord-267965-84sotgds	379	9	inflammatory	inflammatory	JJ
cord-267965-84sotgds	379	10	diseases	disease	NNS
cord-267965-84sotgds	379	11	Immunological	Immunological	NNP
cord-267965-84sotgds	379	12	Genome	Genome	NNP
cord-267965-84sotgds	379	13	Project	Project	NNP
cord-267965-84sotgds	379	14	and	and	CC
cord-267965-84sotgds	379	15	systems	system	NNS
cord-267965-84sotgds	379	16	immunology	immunology	NN
cord-267965-84sotgds	380	1	Quantitative	quantitative	JJ
cord-267965-84sotgds	380	2	trait	trait	NN
cord-267965-84sotgds	380	3	mapping	mapping	NN
cord-267965-84sotgds	380	4	in	in	IN
cord-267965-84sotgds	380	5	Diversity	Diversity	NNP
cord-267965-84sotgds	380	6	Outbred	Outbred	NNP
cord-267965-84sotgds	380	7	mice	mouse	NNS
cord-267965-84sotgds	380	8	identifies	identify	VBZ
cord-267965-84sotgds	380	9	two	two	CD
cord-267965-84sotgds	380	10	genomic	genomic	JJ
cord-267965-84sotgds	380	11	regions	region	NNS
cord-267965-84sotgds	380	12	associated	associate	VBN
cord-267965-84sotgds	380	13	with	with	IN
cord-267965-84sotgds	380	14	heart	heart	NN
cord-267965-84sotgds	380	15	size	size	NN
cord-267965-84sotgds	380	16	SIFT	sift	VB
cord-267965-84sotgds	380	17	web	web	NN
cord-267965-84sotgds	380	18	server	server	NN
cord-267965-84sotgds	380	19	:	:	:
cord-267965-84sotgds	380	20	predicting	predict	VBG
cord-267965-84sotgds	380	21	effects	effect	NNS
cord-267965-84sotgds	380	22	of	of	IN
cord-267965-84sotgds	380	23	amino	amino	NN
cord-267965-84sotgds	380	24	acid	acid	NN
cord-267965-84sotgds	380	25	substitutions	substitution	NNS
cord-267965-84sotgds	380	26	on	on	IN
cord-267965-84sotgds	380	27	proteins	protein	NNS
cord-267965-84sotgds	380	28	High	high	JJ
cord-267965-84sotgds	380	29	anti	anti	JJ
cord-267965-84sotgds	380	30	-	-	JJ
cord-267965-84sotgds	380	31	Dengue	dengue	JJ
cord-267965-84sotgds	380	32	virus	virus	NN
cord-267965-84sotgds	380	33	activity	activity	NN
cord-267965-84sotgds	380	34	of	of	IN
cord-267965-84sotgds	380	35	the	the	DT
cord-267965-84sotgds	380	36	OAS	OAS	NNP
cord-267965-84sotgds	380	37	gene	gene	NN
cord-267965-84sotgds	380	38	family	family	NN
cord-267965-84sotgds	380	39	is	be	VBZ
cord-267965-84sotgds	380	40	associated	associate	VBN
cord-267965-84sotgds	380	41	with	with	IN
cord-267965-84sotgds	380	42	increased	increase	VBN
cord-267965-84sotgds	380	43	severity	severity	NN
cord-267965-84sotgds	380	44	of	of	IN
cord-267965-84sotgds	380	45	Dengue	Dengue	NNP
cord-267965-84sotgds	380	46	High	high	JJ
cord-267965-84sotgds	380	47	-	-	HYPH
cord-267965-84sotgds	380	48	resolution	resolution	NN
cord-267965-84sotgds	380	49	genetic	genetic	JJ
cord-267965-84sotgds	380	50	mapping	mapping	NN
cord-267965-84sotgds	380	51	in	in	IN
cord-267965-84sotgds	380	52	the	the	DT
cord-267965-84sotgds	380	53	diversity	diversity	NN
cord-267965-84sotgds	380	54	outbred	outbred	JJ
cord-267965-84sotgds	380	55	mouse	mouse	NN
cord-267965-84sotgds	380	56	population	population	NN
cord-267965-84sotgds	380	57	identifies	identify	VBZ
cord-267965-84sotgds	380	58	Apobec1	Apobec1	NNP
cord-267965-84sotgds	380	59	as	as	IN
cord-267965-84sotgds	380	60	a	a	DT
cord-267965-84sotgds	380	61	candidate	candidate	NN
cord-267965-84sotgds	380	62	gene	gene	NN
cord-267965-84sotgds	380	63	for	for	IN
cord-267965-84sotgds	380	64	atherosclerosis	atherosclerosis	NN
cord-267965-84sotgds	381	1	Tuberculosis	tuberculosis	NN
cord-267965-84sotgds	381	2	susceptibility	susceptibility	NN
cord-267965-84sotgds	381	3	and	and	CC
cord-267965-84sotgds	381	4	vaccine	vaccine	NN
cord-267965-84sotgds	381	5	protection	protection	NN
cord-267965-84sotgds	381	6	are	be	VBP
cord-267965-84sotgds	381	7	independently	independently	RB
cord-267965-84sotgds	381	8	controlled	control	VBN
cord-267965-84sotgds	381	9	by	by	IN
cord-267965-84sotgds	381	10	host	host	NN
cord-267965-84sotgds	381	11	genotype	genotype	NN
cord-267965-84sotgds	381	12	Influence	influence	NN
cord-267965-84sotgds	381	13	of	of	IN
cord-267965-84sotgds	381	14	early	early	JJ
cord-267965-84sotgds	381	15	life	life	NN
cord-267965-84sotgds	381	16	exposure	exposure	NN
cord-267965-84sotgds	381	17	,	,	,
cord-267965-84sotgds	381	18	host	host	NN
cord-267965-84sotgds	381	19	genetics	genetics	NN
cord-267965-84sotgds	381	20	and	and	CC
cord-267965-84sotgds	381	21	diet	diet	NN
cord-267965-84sotgds	381	22	on	on	IN
cord-267965-84sotgds	381	23	the	the	DT
cord-267965-84sotgds	381	24	mouse	mouse	NN
cord-267965-84sotgds	381	25	gut	gut	NN
cord-267965-84sotgds	381	26	microbiome	microbiome	NN
cord-267965-84sotgds	381	27	and	and	CC
cord-267965-84sotgds	381	28	metabolome	metabolome	NN
cord-267965-84sotgds	381	29	Genomes	Genomes	NNPS
cord-267965-84sotgds	381	30	of	of	IN
cord-267965-84sotgds	381	31	the	the	DT
cord-267965-84sotgds	381	32	mouse	mouse	NN
cord-267965-84sotgds	381	33	Collaborative	Collaborative	NNP
cord-267965-84sotgds	381	34	Cross	Cross	NNP
cord-267965-84sotgds	381	35	Animal	Animal	NNP
cord-267965-84sotgds	381	36	models	model	NNS
cord-267965-84sotgds	381	37	of	of	IN
cord-267965-84sotgds	381	38	Ebolavirus	Ebolavirus	NNP
cord-267965-84sotgds	381	39	infection	infection	NN
cord-267965-84sotgds	381	40	Development	Development	NNP
cord-267965-84sotgds	381	41	of	of	IN
cord-267965-84sotgds	381	42	mouse	mouse	NN
cord-267965-84sotgds	381	43	models	model	NNS
cord-267965-84sotgds	381	44	for	for	IN
cord-267965-84sotgds	381	45	analysis	analysis	NN
cord-267965-84sotgds	381	46	of	of	IN
cord-267965-84sotgds	381	47	human	human	JJ
cord-267965-84sotgds	381	48	virus	virus	NN
cord-267965-84sotgds	381	49	infections	infection	NNS
cord-267965-84sotgds	381	50	Genomic	genomic	JJ
cord-267965-84sotgds	381	51	responses	response	NNS
cord-267965-84sotgds	381	52	in	in	IN
cord-267965-84sotgds	381	53	mouse	mouse	NN
cord-267965-84sotgds	381	54	models	model	NNS
cord-267965-84sotgds	381	55	greatly	greatly	RB
cord-267965-84sotgds	381	56	mimic	mimic	VBP
cord-267965-84sotgds	381	57	human	human	JJ
cord-267965-84sotgds	381	58	inflammatory	inflammatory	JJ
cord-267965-84sotgds	381	59	diseases	disease	NNS
cord-267965-84sotgds	382	1	A	a	DT
cord-267965-84sotgds	382	2	homozygous	homozygous	JJ
cord-267965-84sotgds	382	3	nonsense	nonsense	NN
cord-267965-84sotgds	382	4	mutation	mutation	NN
cord-267965-84sotgds	382	5	(	(	-LRB-
cord-267965-84sotgds	382	6	428G->A	428g->a	CD
cord-267965-84sotgds	382	7	)	)	-RRB-
cord-267965-84sotgds	382	8	in	in	IN
cord-267965-84sotgds	382	9	the	the	DT
cord-267965-84sotgds	382	10	human	human	JJ
cord-267965-84sotgds	382	11	secretor	secretor	NN
cord-267965-84sotgds	383	1	(	(	-LRB-
cord-267965-84sotgds	383	2	FUT2	FUT2	NNP
cord-267965-84sotgds	383	3	)	)	-RRB-
cord-267965-84sotgds	383	4	gene	gene	NN
cord-267965-84sotgds	383	5	provides	provide	VBZ
cord-267965-84sotgds	383	6	resistance	resistance	NN
cord-267965-84sotgds	383	7	to	to	IN
cord-267965-84sotgds	383	8	symptomatic	symptomatic	JJ
cord-267965-84sotgds	383	9	norovirus	norovirus	NN
cord-267965-84sotgds	383	10	(	(	-LRB-
cord-267965-84sotgds	383	11	GGII	GGII	NNP
cord-267965-84sotgds	383	12	)	)	-RRB-
cord-267965-84sotgds	383	13	infections	infection	NNS
cord-267965-84sotgds	383	14	Genetic	genetic	JJ
cord-267965-84sotgds	383	15	dissection	dissection	NN
cord-267965-84sotgds	383	16	of	of	IN
cord-267965-84sotgds	383	17	complex	complex	JJ
cord-267965-84sotgds	383	18	and	and	CC
cord-267965-84sotgds	383	19	quantitative	quantitative	JJ
cord-267965-84sotgds	383	20	traits	trait	NNS
cord-267965-84sotgds	383	21	:	:	:
cord-267965-84sotgds	383	22	from	from	IN
cord-267965-84sotgds	383	23	fantasy	fantasy	NN
cord-267965-84sotgds	383	24	to	to	IN
cord-267965-84sotgds	383	25	reality	reality	NN
cord-267965-84sotgds	383	26	via	via	IN
cord-267965-84sotgds	383	27	a	a	DT
cord-267965-84sotgds	383	28	community	community	NN
cord-267965-84sotgds	383	29	effort	effort	NN
cord-267965-84sotgds	383	30	Genome	genome	NN
cord-267965-84sotgds	383	31	-	-	HYPH
cord-267965-84sotgds	383	32	wide	wide	JJ
cord-267965-84sotgds	383	33	association	association	NN
cord-267965-84sotgds	383	34	study	study	NN
cord-267965-84sotgds	383	35	indicates	indicate	VBZ
cord-267965-84sotgds	383	36	two	two	CD
cord-267965-84sotgds	383	37	novel	novel	JJ
cord-267965-84sotgds	383	38	resistance	resistance	NN
cord-267965-84sotgds	383	39	loci	locus	NNS
cord-267965-84sotgds	383	40	for	for	IN
cord-267965-84sotgds	383	41	severe	severe	JJ
cord-267965-84sotgds	383	42	malaria	malaria	NN
cord-267965-84sotgds	383	43	Toll	toll	NN
cord-267965-84sotgds	383	44	-	-	HYPH
cord-267965-84sotgds	383	45	like	like	JJ
cord-267965-84sotgds	383	46	receptor	receptor	NN
cord-267965-84sotgds	383	47	3	3	CD
cord-267965-84sotgds	383	48	signaling	signal	VBG
cord-267965-84sotgds	383	49	via	via	IN
cord-267965-84sotgds	383	50	TRIF	TRIF	NNP
cord-267965-84sotgds	383	51	contributes	contribute	VBZ
cord-267965-84sotgds	383	52	to	to	IN
cord-267965-84sotgds	383	53	a	a	DT
cord-267965-84sotgds	383	54	protective	protective	JJ
cord-267965-84sotgds	383	55	innate	innate	JJ
cord-267965-84sotgds	383	56	immune	immune	JJ
cord-267965-84sotgds	383	57	response	response	NN
cord-267965-84sotgds	383	58	to	to	IN
cord-267965-84sotgds	384	1	severe	severe	JJ
cord-267965-84sotgds	384	2	acute	acute	JJ
cord-267965-84sotgds	384	3	respiratory	respiratory	JJ
cord-267965-84sotgds	384	4	syndrome	syndrome	NN
cord-267965-84sotgds	384	5	coronavirus	coronavirus	NN
cord-267965-84sotgds	384	6	infection	infection	NN
cord-267965-84sotgds	384	7	Global	global	JJ
cord-267965-84sotgds	384	8	analyses	analysis	NNS
cord-267965-84sotgds	384	9	of	of	IN
cord-267965-84sotgds	384	10	human	human	JJ
cord-267965-84sotgds	384	11	immune	immune	JJ
cord-267965-84sotgds	384	12	variation	variation	NN
cord-267965-84sotgds	384	13	reveal	reveal	VBP
cord-267965-84sotgds	384	14	baseline	baseline	JJ
cord-267965-84sotgds	384	15	predictors	predictor	NNS
cord-267965-84sotgds	384	16	of	of	IN
cord-267965-84sotgds	384	17	postvaccination	postvaccination	NN
cord-267965-84sotgds	384	18	responses	response	NNS
cord-267965-84sotgds	384	19	Mapping	Mapping	NNP
cord-267965-84sotgds	384	20	in	in	IN
cord-267965-84sotgds	384	21	structured	structured	JJ
cord-267965-84sotgds	384	22	populations	population	NNS
cord-267965-84sotgds	384	23	by	by	IN
cord-267965-84sotgds	384	24	resample	resample	NN
cord-267965-84sotgds	384	25	model	model	NN
cord-267965-84sotgds	384	26	averaging	average	VBG
cord-267965-84sotgds	384	27	Editor	Editor	NNP
cord-267965-84sotgds	384	28	's	's	POS
cord-267965-84sotgds	384	29	highlight	highlight	NN
cord-267965-84sotgds	384	30	:	:	:
cord-267965-84sotgds	384	31	Collaborative	Collaborative	NNP
cord-267965-84sotgds	384	32	Cross	Cross	NNP
cord-267965-84sotgds	384	33	mouse	mouse	NN
cord-267965-84sotgds	384	34	population	population	NN
cord-267965-84sotgds	384	35	enables	enable	VBZ
cord-267965-84sotgds	384	36	refinements	refinement	NNS
cord-267965-84sotgds	384	37	to	to	IN
cord-267965-84sotgds	384	38	characterization	characterization	NN
cord-267965-84sotgds	384	39	of	of	IN
cord-267965-84sotgds	384	40	the	the	DT
cord-267965-84sotgds	384	41	variability	variability	NN
cord-267965-84sotgds	384	42	in	in	IN
cord-267965-84sotgds	384	43	toxicokinetics	toxicokinetic	NNS
cord-267965-84sotgds	384	44	of	of	IN
cord-267965-84sotgds	384	45	trichloroethylene	trichloroethylene	NN
cord-267965-84sotgds	384	46	and	and	CC
cord-267965-84sotgds	384	47	provides	provide	VBZ
cord-267965-84sotgds	384	48	genetic	genetic	JJ
cord-267965-84sotgds	384	49	evidence	evidence	NN
cord-267965-84sotgds	384	50	for	for	IN
cord-267965-84sotgds	384	51	the	the	DT
cord-267965-84sotgds	384	52	role	role	NN
cord-267965-84sotgds	384	53	of	of	IN
cord-267965-84sotgds	384	54	PPAR	PPAR	NNP
cord-267965-84sotgds	384	55	pathway	pathway	NN
cord-267965-84sotgds	384	56	in	in	IN
cord-267965-84sotgds	384	57	its	-PRON-	PRP$
cord-267965-84sotgds	384	58	oxidative	oxidative	JJ
cord-267965-84sotgds	384	59	metabolism	metabolism	NN
cord-267965-84sotgds	384	60	Susceptibility	susceptibility	NN
cord-267965-84sotgds	384	61	to	to	IN
cord-267965-84sotgds	384	62	Klebsiella	Klebsiella	NNP
cord-267965-84sotgds	384	63	pneumonaie	pneumonaie	NN
cord-267965-84sotgds	384	64	infection	infection	NN
cord-267965-84sotgds	384	65	in	in	IN
cord-267965-84sotgds	384	66	collaborative	collaborative	JJ
cord-267965-84sotgds	384	67	cross	cross	NN
cord-267965-84sotgds	384	68	mice	mice	NN
cord-267965-84sotgds	384	69	is	be	VBZ
cord-267965-84sotgds	384	70	a	a	DT
cord-267965-84sotgds	384	71	complex	complex	JJ
cord-267965-84sotgds	384	72	trait	trait	NN
cord-267965-84sotgds	384	73	controlled	control	VBN
cord-267965-84sotgds	384	74	by	by	IN
cord-267965-84sotgds	384	75	at	at	RB
cord-267965-84sotgds	384	76	least	least	RBS
cord-267965-84sotgds	384	77	three	three	CD
cord-267965-84sotgds	384	78	loci	locus	NNS
cord-267965-84sotgds	384	79	acting	act	VBG
cord-267965-84sotgds	384	80	at	at	IN
cord-267965-84sotgds	384	81	different	different	JJ
cord-267965-84sotgds	384	82	time	time	NN
cord-267965-84sotgds	384	83	points	point	NNS
cord-267965-84sotgds	384	84	Natural	natural	JJ
cord-267965-84sotgds	384	85	resistance	resistance	NN
cord-267965-84sotgds	384	86	to	to	IN
cord-267965-84sotgds	384	87	infection	infection	NN
cord-267965-84sotgds	384	88	with	with	IN
cord-267965-84sotgds	384	89	intracellular	intracellular	JJ
cord-267965-84sotgds	384	90	parasites	parasite	NNS
cord-267965-84sotgds	384	91	:	:	:
cord-267965-84sotgds	384	92	isolation	isolation	NN
cord-267965-84sotgds	384	93	of	of	IN
cord-267965-84sotgds	384	94	a	a	DT
cord-267965-84sotgds	384	95	candidate	candidate	NN
cord-267965-84sotgds	384	96	for	for	IN
cord-267965-84sotgds	384	97	Bcg	Bcg	NNP
cord-267965-84sotgds	385	1	The	the	DT
cord-267965-84sotgds	385	2	virome	virome	NN
cord-267965-84sotgds	385	3	in	in	IN
cord-267965-84sotgds	385	4	mammalian	mammalian	JJ
cord-267965-84sotgds	385	5	physiology	physiology	NN
cord-267965-84sotgds	385	6	and	and	CC
cord-267965-84sotgds	385	7	disease	disease	NN
cord-267965-84sotgds	385	8	A	a	DT
cord-267965-84sotgds	385	9	large	large	JJ
cord-267965-84sotgds	385	10	-	-	HYPH
cord-267965-84sotgds	385	11	scale	scale	NN
cord-267965-84sotgds	385	12	genome	genome	NN
cord-267965-84sotgds	385	13	-	-	HYPH
cord-267965-84sotgds	385	14	wide	wide	JJ
cord-267965-84sotgds	385	15	association	association	NN
cord-267965-84sotgds	385	16	and	and	CC
cord-267965-84sotgds	385	17	metaanalysis	metaanalysis	NN
cord-267965-84sotgds	385	18	identified	identify	VBD
cord-267965-84sotgds	385	19	four	four	CD
cord-267965-84sotgds	385	20	novel	novel	JJ
cord-267965-84sotgds	385	21	susceptibility	susceptibility	NN
cord-267965-84sotgds	385	22	loci	locus	NNS
cord-267965-84sotgds	385	23	for	for	IN
cord-267965-84sotgds	385	24	leprosy	leprosy	NN
cord-267965-84sotgds	385	25	Innate	innate	VBP
cord-267965-84sotgds	385	26	immune	immune	JJ
cord-267965-84sotgds	385	27	response	response	NN
cord-267965-84sotgds	385	28	in	in	IN
cord-267965-84sotgds	385	29	Th1-and	th1-and	NN
cord-267965-84sotgds	385	30	Th2-dominant	th2-dominant	JJ
cord-267965-84sotgds	385	31	mouse	mouse	NN
cord-267965-84sotgds	385	32	strains	strain	VBZ
cord-267965-84sotgds	385	33	Genomic	genomic	JJ
cord-267965-84sotgds	385	34	profiling	profiling	NN
cord-267965-84sotgds	385	35	of	of	IN
cord-267965-84sotgds	385	36	collaborative	collaborative	JJ
cord-267965-84sotgds	385	37	cross	cross	NN
cord-267965-84sotgds	385	38	founder	founder	NN
cord-267965-84sotgds	385	39	mice	mouse	NNS
cord-267965-84sotgds	385	40	infected	infect	VBN
cord-267965-84sotgds	385	41	with	with	IN
cord-267965-84sotgds	385	42	respiratory	respiratory	JJ
cord-267965-84sotgds	385	43	viruses	virus	NNS
cord-267965-84sotgds	385	44	reveals	reveal	VBZ
cord-267965-84sotgds	385	45	novel	novel	JJ
cord-267965-84sotgds	385	46	transcripts	transcript	NNS
cord-267965-84sotgds	385	47	and	and	CC
cord-267965-84sotgds	385	48	infectionrelated	infectionrelated	JJ
cord-267965-84sotgds	385	49	strain	strain	NN
cord-267965-84sotgds	385	50	-	-	HYPH
cord-267965-84sotgds	385	51	specific	specific	JJ
cord-267965-84sotgds	385	52	gene	gene	NN
cord-267965-84sotgds	385	53	and	and	CC
cord-267965-84sotgds	385	54	isoform	isoform	NN
cord-267965-84sotgds	385	55	expression	expression	NN
cord-267965-84sotgds	385	56	Using	use	VBG
cord-267965-84sotgds	385	57	progenitor	progenitor	JJ
cord-267965-84sotgds	385	58	strain	strain	VB
cord-267965-84sotgds	385	59	information	information	NN
cord-267965-84sotgds	385	60	to	to	TO
cord-267965-84sotgds	385	61	identify	identify	VB
cord-267965-84sotgds	385	62	quantitative	quantitative	JJ
cord-267965-84sotgds	385	63	trait	trait	NN
cord-267965-84sotgds	385	64	nucleotides	nucleotide	NNS
cord-267965-84sotgds	385	65	in	in	IN
cord-267965-84sotgds	385	66	outbred	outbred	JJ
cord-267965-84sotgds	385	67	mice	mouse	NNS
cord-267965-84sotgds	385	68	Identification	identification	NN
cord-267965-84sotgds	385	69	of	of	IN
cord-267965-84sotgds	385	70	new	new	JJ
cord-267965-84sotgds	385	71	loci	locus	NNS
cord-267965-84sotgds	385	72	involved	involve	VBN
cord-267965-84sotgds	385	73	in	in	IN
cord-267965-84sotgds	385	74	the	the	DT
cord-267965-84sotgds	385	75	host	host	NN
cord-267965-84sotgds	385	76	susceptibility	susceptibility	NN
cord-267965-84sotgds	385	77	to	to	IN
cord-267965-84sotgds	385	78	Salmonella	Salmonella	NNP
cord-267965-84sotgds	385	79	Typhimurium	Typhimurium	NNP
cord-267965-84sotgds	385	80	in	in	IN
cord-267965-84sotgds	385	81	collaborative	collaborative	JJ
cord-267965-84sotgds	385	82	cross	cross	NN
cord-267965-84sotgds	385	83	mice	mice	NN
cord-267965-84sotgds	386	1	We	-PRON-	PRP
cord-267965-84sotgds	386	2	would	would	MD
cord-267965-84sotgds	386	3	like	like	VB
cord-267965-84sotgds	386	4	to	to	TO
cord-267965-84sotgds	386	5	thank	thank	VB
cord-267965-84sotgds	386	6	Sharon	Sharon	NNP
cord-267965-84sotgds	386	7	Taft	Taft	NNP
cord-267965-84sotgds	386	8	-	-	HYPH
cord-267965-84sotgds	386	9	Benz	Benz	NNP
cord-267965-84sotgds	386	10	,	,	,
cord-267965-84sotgds	386	11	Sanjay	Sanjay	NNP
cord-267965-84sotgds	386	12	Sarkar	Sarkar	NNP
cord-267965-84sotgds	386	13	,	,	,
cord-267965-84sotgds	386	14	Emily	Emily	NNP
cord-267965-84sotgds	386	15	Madden	Madden	NNP
cord-267965-84sotgds	386	16	,	,	,
cord-267965-84sotgds	386	17	and	and	CC
cord-267965-84sotgds	386	18	Brea	Brea	NNP
cord-267965-84sotgds	386	19	Hampton	Hampton	NNP
cord-267965-84sotgds	386	20	for	for	IN
cord-267965-84sotgds	386	21	critical	critical	JJ
cord-267965-84sotgds	386	22	reading	reading	NN
cord-267965-84sotgds	386	23	of	of	IN
cord-267965-84sotgds	386	24	the	the	DT
cord-267965-84sotgds	386	25	manuscript	manuscript	NN
cord-267965-84sotgds	386	26	.	.	.
cord-267965-84sotgds	387	1	Chromosome	chromosome	NN
cord-267965-84sotgds	387	2	ideograms	ideogram	NNS
cord-267965-84sotgds	387	3	shown	show	VBN
cord-267965-84sotgds	387	4	in	in	IN
cord-267965-84sotgds	387	5	Figure	figure	NN
cord-267965-84sotgds	387	6	2	2	CD
cord-267965-84sotgds	387	7	were	be	VBD
cord-267965-84sotgds	387	8	generated	generate	VBN
cord-267965-84sotgds	387	9	using	use	VBG
cord-267965-84sotgds	387	10	the	the	DT
cord-267965-84sotgds	387	11	karyoploteR	karyoploteR	NNP
cord-267965-84sotgds	387	12	package	package	NN
cord-267965-84sotgds	387	13	for	for	IN
cord-267965-84sotgds	387	14	R	r	NN
cord-267965-84sotgds	387	15	(	(	-LRB-
cord-267965-84sotgds	387	16	Gel	Gel	NNP
cord-267965-84sotgds	387	17	and	and	CC
cord-267965-84sotgds	387	18	Serra	Serra	NNP
cord-267965-84sotgds	387	19	,	,	,
cord-267965-84sotgds	387	20	2017	2017	CD
cord-267965-84sotgds	387	21	)	)	-RRB-
cord-267965-84sotgds	387	22	.	.	.
cord-267965-84sotgds	388	1	This	this	DT
cord-267965-84sotgds	388	2	work	work	NN
cord-267965-84sotgds	388	3	was	be	VBD
cord-267965-84sotgds	388	4	supported	support	VBN
cord-267965-84sotgds	388	5	by	by	IN
cord-267965-84sotgds	388	6	U19	U19	NNP
cord-267965-84sotgds	388	7	AI100625	AI100625	NNP
cord-267965-84sotgds	388	8	and	and	CC
cord-267965-84sotgds	388	9	P01AI132130	P01AI132130	NNP
cord-267965-84sotgds	388	10	.	.	.
cord-267965-84sotgds	389	1	K.E.N.	K.E.N.	NNP
cord-267965-84sotgds	389	2	received	receive	VBD
cord-267965-84sotgds	389	3	support	support	NN
cord-267965-84sotgds	389	4	from	from	IN
cord-267965-84sotgds	389	5	T32AI007419	T32AI007419	NNP
cord-267965-84sotgds	389	6	.	.	.