id author title date pages extension mime words sentences flesch summary cache txt en-wikipedia-org-6462 Thirst - Wikipedia .html text/html 2394 343 53 If the water volume of the body falls below a certain threshold or the osmolite concentration becomes too high, structures in the brain detect changes in blood constituents and signal thirst.[2] The loss of blood volume is detected by cells in the kidneys and triggers thirst for both water and salt via the renin-angiotensin system.[2][3] Angiotensin II then travels in the blood until it reaches the posterior pituitary gland and the adrenal cortex, where it causes a cascade effect of hormones that cause the kidneys to retain water and sodium, increasing blood pressure.[3] It is also responsible for the initiation of drinking behavior and salt appetite via the subfornical organ.[2] Because sodium is also lost from the plasma in hypovolemia, the body's need for salt proportionately increases in addition to thirst in such cases.[3] This is also a result of the renin-angiotensin system activation.[medical citation needed] ./cache/en-wikipedia-org-6462.html ./txt/en-wikipedia-org-6462.txt