id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
www-sciencemag-org-7011		Superresolution microscopy | Science | AAAS			.html	text/html	3633	203	50	In 2006, Xiaowei Zhuang's team at Harvard University first described the superresolution technique known as stochastic optical reconstruction microscopy (STORM), a single-molecule localization method whose 20-nm lateral (xy) resolution beats the diffraction limit by a full order of magnitude. Published in 2013, Zhuang's study is "a seminal contribution," agrees Joerg Bewersdorf, Associate Professor of Cell Biology and Biomedical Engineering at the Yale University School of Medicine, who builds superresolution microscopes (including one now commercialized by Bruker) in his lab. Stimulated emission depletion (STED), reversible saturable optical fluorescence transitions (RESOLFT), and structured illumination microscopy (SIM), conversely, use "patterns of light … that determine where the molecules are active and where the molecules are off," says Hell, who developed both STED and RESOLFT and cofounded a company called Abberior to commercialize fluorophores for those and other superresolution methods.	./cache/www-sciencemag-org-7011.html	./txt/www-sciencemag-org-7011.txt