id author title date pages extension mime words sentences flesch summary cache txt work_2vnerksmoneubbpetxouhlptfy Krista Casazza Nutrition as Medicine to Improve Outcomes in Adolescents Sustaining a Sports-related Concussion 2017 9 .pdf application/pdf 9283 827 49 Nutrition as Medicine to Improve Outcomes in Adolescents Sustaining a Sports-related Concussion Sports-related concussion (SRC), like other acute traumatic brain events triggered by the concussive impact.7 However, reports linking the injury to long-term declines in cognitive functioning,8,9 depression and mild cognitive impairment has propagated substantial trauma,13 rodent models and cell culture towards longitudinal studies assessing the shortand long-term intricate cognitive, emotional, behavioral, neurobiological and neuropathological consequences of concussions that can also identify predictors and modifiers metabolic cascade post-concussion, and identify key nutrients, that if supplemented immediately post-injury, Abbreviations: SRC, sports-related concussion; TBI, traumatic brain injury; PUFA, diphosphate; CRP, C-reactive protein; ALA, alpha-linoleic acid; VDR, vitamin D receptor; BBB, blood brain barrier; NADPH, nicotinamide adenine dinucleotide phosphate; TCA, tricarboxylic acid; PARP-1, poly-adenosine diphosphate-ribose polymerase-1; GH, growth hormone. In animal models, creatine supplementation pre-TBI has demonstrated a neuroprotective effect on mitochondrial function and secondary injury.57 Human studies, though A review of the neuroprotective role of vitamin D in traumatic brain injury with implications for supplementation post-concussion. ./cache/work_2vnerksmoneubbpetxouhlptfy.pdf ./txt/work_2vnerksmoneubbpetxouhlptfy.txt