id author title date pages extension mime words sentences flesch summary cache txt work_biwodjvfjfet7eh2iu2bhauiwq Jack C. de la Torre Cardiovascular Risk Factors Promote Brain Hypoperfusion Leading to Cognitive Decline and Dementia 2012 15 .pdf application/pdf 13727 1164 56 blood flow stemming from abnormalities in the heart-brain vascular loop ostensibly increases the probability of developing It may develop from atherosclerosis, arterial stiffness, or cardiovascular disease which can impair cerebral autoregulation homeostasis and result in brain hypoperfusion (Figure 2). Cardiovascular risk factors leading to brain hypoperfusion and cognitive loss Figure 1: Cardiovascular risk factors reported to promote progressive cognitive decline leading to dementia in the elderly population. hypertension, and atherosclerosis and is believed to result in brain microvascular damage, leading to cerebral hypoperfusion and cognitive factor to Alzheimer's dementia, increases the risk of coronary heart disease by about 40% [114]. flow and metabolism studies in multi-infarct dementia," Alzheimer Disease and Associated Disorders, vol. A. Silver, "ATP and brain function," Journal of Cerebral Blood Flow and Metabolism, vol. cognitive impairment and its subtypes: results of a population-based case-control study," Journal of Alzheimer's Disease, vol. ./cache/work_biwodjvfjfet7eh2iu2bhauiwq.pdf ./txt/work_biwodjvfjfet7eh2iu2bhauiwq.txt