id author title date pages extension mime words sentences flesch summary cache txt work_df4os2mi6zcshcikihumzaazfm Virginie Rascol CASSIOPE: An expert system for conserved regions searches 2009 11 .pdf application/pdf 5509 594 50 CASSIOPE: An expert system for conserved regions searches CASSIOPE: An expert system for conserved regions searches many years comparative genomics and analysis of conserved chromosomal regions have helped to CASSIOPE automatically identifies statistically significant conserved regions between multiple Conclusion: CASSIOPE makes it possible to study conserved regions from a chosen query genetic region and to infer conserved gene clusters based on phylogenies and statistical tests assessing the regions are frequently defined through BLAST [2] or alignment by similarity search to determine putative "orthologous" genes [3,4]. and databases (Phig's [5]), Ensembl [6]) provide information on conserved regions across different species but even when they do use phylogenetic methods, there is no statistical processing assessing the significance of the conserved regions. conserved genomic regions requires phylogenetic orthology assessment, statistical testing, and as many available regions (conserved genes clusters in the same genome) new conserved regions with species that were not computed in Ensembl databases. ./cache/work_df4os2mi6zcshcikihumzaazfm.pdf ./txt/work_df4os2mi6zcshcikihumzaazfm.txt