Introduction “[Susan] has been suffering much from the headache and six leeches a day for ten days together relieved her so lit- tle that we thought it right to change our measures – and being convinced on examination that much of the evil lay in her gum, I persuaded her to attack the disorder there. She has accordingly had three teeth drawn, and is decid- edly better, but her nerves are a good deal deranged. She can only speak in a whisper – and fainted away twice this morning …” Jane Austen, Sanditon (1817) As this quotation shows, the difficulty in establishing the efficacy of treatments for persistent headaches is not a new one, and experimentation with new modalities, though often encouraged, may not be without side effects. There are data supporting the efficacy of acupuncture for the treatment of headache [1] and recent- ly a randomised controlled trial found it both efficacious [2] and cost-effective [3] for the treatment of chronic headache in primary care. Questions of efficacy aside, data showing how often acupuncture is used for the treat- ment of headache have not been identified. Acupuncture treatment in the United Kingdom is available on an ad hoc basis, sometimes from primary care practitioners, sometimes from private practitioners. There is no stan- dardised, university-based, structure for training in acupuncture in the UK. The aim of this study was to ascertain how often acupuncture had been used by patients with headache prior to referral to general neurology outpatient clinics. A subsidiary aim was to ascertain how many headache patients would be prepared to try acupuncture treatment, and how many would be put off by the use of needles. J Headache Pain (2005) 6:97–99 DOI 10.1007/s10194-005-0160-7 Acupuncture use for the treatment of headache prior to neurological referral B R I E F R E P O R T A.J. Larner (�) Walton Centre for Neurology and Neurosurgery, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK e-mail: a.larner@thewaltoncentre.nhs.uk Fax: +44-151-529-5513 A.J. Larner Abstract Acupuncture is a popular complementary treatment for various pain syndromes. Some studies claim efficacy in the treatment of primary headache syndromes. However, data on the frequency of acupuncture use by patients with headache prior to neurological referral have not been identified. In this study, 12% of patients with headache attending general neurology outpatient clinics had already received acupuncture; of the remainder, 73% said they would be willing to try it. Key words Acupuncture • Headache • Treatment Received: 19 November 2004 Accepted in revised form: 16 February 2005 Published online: 8 April 2005 98 Materials and methods Consecutive new outpatient referrals to general adult neurology clinics served by one consultant neurologist at three hospitals in north-west England over a six-month period were assessed. Those in whom the principal reason for referral or the principal com- plaint was headache were asked (if they had not already volun- teered this information) whether they had ever had acupuncture treatment, and if so the indications for its use, how many treatment sessions were given, and its subjective efficacy. Those who had not received acupuncture were asked whether or not they would be prepared to try it as a treatment for their headaches; if not will- ing, reasons were sought. Diagnosis of headache syndromes was based upon internationally agreed criteria [4]. Results Over the 6-month period (mid April to mid October 2004), 481 new referrals were seen in 53 consecutive clinics. The principal complaint was headache in 115 (24%; 95% con- fidence interval [CI]: 20%–28%). Demographic and diag- nostic data are shown in Table 1. Referral source was gen- eral practitioner in 105 cases and another hospital practi- tioner in 10. All patients gave verbal consent to answer questions about acupuncture treatment. Twenty patients with headache (17%; 95% CI: 10%–24%) had been treated with acupuncture at some time. In 14 patients this was for headache (12% of the total headache cohort, 95% CI: 6%–18%; see Table 1 for demographic and diagnostic data), in six for other reasons (other pain syndromes: 4; obses- sive-compulsive disorder: 1; smoking cessation: 1). Only three headache patients (21%) volunteered information about their previous acupuncture treatment. The reported number of acupuncture treatment ses- sions for the headache patients ranged from 1 to 10 (mean=6; mode=6; median=6). Eleven reported that acupuncture was not helpful (one after initial benefit); three reported benefit (two with chronic migraine, one with migraine with aura). Of the 95 patients who had never received acupunc- ture, 69 (73%; 95% CI: 64%–82%) said they would be prepared to try it if it were a recognised treatment for headache. Of the 26 expressing no interest or no opinion, 11 (12%; 95% CI: 5%–19%) made comments suggesting an aversion to needles (hated needles, were squeamish, or had a “needle phobia”). Discussion The frequency of headache in this general neurology out- patient clinic population (24%), patient age and gender, and preponderance of chronic headache were similar to results in cohorts of headache patients from other general neurological outpatient clinics [5, 6]. The survey methodology was simple. Results were dependent upon patient recall, and hence liable to recall bias, but nonetheless provided some information about the frequency of acupuncture use for the treatment of headache prior to neurological referral. Acupuncture had already been used by 12%, although only one-fifth of these volunteered the fact. The apparently low efficacy of acupuncture in this cohort (3/14) is not surprising: pre- sumably referral would not have happened had acupunc- ture resolved headache. No patient with fewer than 6 treatments reported benefit. No patient had 12 treatments, Table 1 Demographic and diagnostic data Headache patients Used acupuncture for headache n 115 14 Age range, years 16–78 16–78 Mean age±SEM, years 39.9±14.1 49.7±14.7 Sex ratio M:F (male %) 43:72 (37%) 4:10 (40%) Specific diagnosis CTTH 58 2 FTTH 7 1 MO 11 – MA 11 2 CM/TM 21 8 MOH 5 1 CH/TAC 2 – CTTH, chronic tension-type headache; FTTH, frequent tension-type headache; MO, migraine without aura; MA, migraine with aura; CM/TM, chronic migraine/transformed migraine; MOH, medication overuse headache; CH/TAC, cluster headache/trigeminal autonomic cephalalgia 99 the limit in the randomised trial in primary care that sug- gested efficacy [2]. Other studies of acupuncture have shown lack of efficacy [7]. Of those not previously treated with acupuncture, the majority (nearly three-quarters) expressed interest in try- ing it, whereas 12% were not interested because of aver- sion to needles. No data about the prevalence of “needle phobia” in the general population have been identified. The problem is occasionally encountered in diabetic patients requiring insulin [8], but this is infrequent and often quickly overcome (MW Mansfield, personal com- munication). These data suggest that if acupuncture became generally available for the treatment of headache, demand would probably be high, as anticipated for any new treatment, irrespective of the potential problems with needles. Although randomised trials suggest efficacy [2], the results of pragmatic (phase IV) studies might be less encouraging. Hence, just over 10% of patients with headache attend- ing general neurology outpatient clinics had already received acupuncture for their headache, and of the remainder nearly 75% expressed interest in trying it. It would be interesting to see if similar data emerged from specialist headache and/or migraine clinics. References 1. Melchart D, Linde K, Fischer P et al (2001) Acupuncture for idiopathic headache. Cochrane Database Syst Rev 1:CD001218 2. Vickers AJ, Rees RW, Zollman CF et al (2004) Acupuncture for chronic headache in primary care: large, prag- matic, randomised trial. BMJ 328:744–747 3. Wonderling D, Vickers AJ, Grieve R, McCarney R (2004) Cost effectiveness analysis of a randomised trial of acupuncture for chronic headache in primary care. BMJ 328:747–749 4. International Headache Society Classification Subcommittee (2004) The international classification of headache disorders, 2nd edn. Cephalalgia 24[Suppl 1]:1–160 5. Carson AJ, Ringbauer B, MacKenzie L, Warlow C, Sharpe M (2000) Neurological disease, emotional disor- der, and disability: they are related. A study of 300 consecutive new referrals to a neurology outpatient department. J Neurol Neurosurg Psychiatry 68:202–206 6. Larner AJ (2003) NHS Direct for headache. J Neurol Neurosurg Psychiatry 74:1698 7. Karst M, Reinhard M, Thurn P, Wiese B, Rollnik J, Fink M (2001) Needle acupuncture in tension-type headache: a randomised placebo-controlled study. Cephalalgia 21:637–642 8. Zambanini A, Feher MD (1997) Needle phobia in type 1 diabetes mellitus. Diabet Med 14:321–323 Introduction Materials and methods Results Discussion References