id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294369-e3jyihvm	del Amo, Julia	Incidence and Severity of COVID-19 in HIV-Positive Persons Receiving Antiretroviral Therapy: A Cohort Study	2020-06-26		.txt	text/plain	3321	190	47	BACKGROUND: The incidence and severity of coronavirus disease 2019 (COVID-19) among HIV-positive persons receiving antiretroviral therapy (ART) have not been characterized in large populations. CONCLUSION: HIV-positive patients receiving TDF/FTC have a lower risk for COVID-19 and related hospitalization than those receiving other therapies. The risks for PCR-confirmed COVID-19 diagnosis, hospitalization, ICU admission, and death among HIVpositive persons receiving ART in Spain were greater in men and those older than 70 years. The lower risk for COVID-19 diagnosis among persons receiving TDF/FTC might be the result of less intensive testing for SARS-CoV-2 infection in this group compared with those receiving other ART regimens. Molecular docking (18 -23) and other in vitro studies (24) suggest that NRTIs, such as TDF, TAF, ABC, and 3TC, might be effective against SARS-CoV-2 infection by inhibiting RNAdRNAp. This also might explain the 32% lower risk for COVID-19 diagnosis in persons receiving ABC/3TC compared with those receiving TAF/FTC.	./cache/cord-294369-e3jyihvm.txt	./txt/cord-294369-e3jyihvm.txt