id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004713-gzts5h0y	Fennestad, K. L.	Pathogenetic observations on pleural effusion disease in rabbits	1985		.txt	text/plain	3596	193	53	A pathogenetic study of pleural effusion disease (PED) in rabbits was made, using the virulent PED agent or virus (PEDV) and an avirulent derivate of this isolate. Support for this contention is the enhancement of virulence of PED virus (PEDV) observed in the "natural" disease and --after its isolation --by continued serial propagation in rabbits at intervals of 3---10 days (Fig. 1) . However, there is also evidence which might suggest that increasing time of persistence of virulent virus in the individual rabbit host may operate in the reverse direction by selecting a population of predominantly avirulent PEDV particles, which appear to be unable to cause disease unless undergoing new rabbit passages at short intervals (t, 6). After infection with the avirulent derivate, the isolates from serum obtained during the entire period of viraemia were demonstrable in serum dilution 10 -1 to 10 -a, but the primary rabbit inoculation of these dilutions never resulted in clinical signs of PED.	./cache/cord-004713-gzts5h0y.txt	./txt/cord-004713-gzts5h0y.txt