id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004755-rmnjs1t6	Welch, Siao-Kun Wan	Monoclonal antibodies to a virulent strain of transmissible gastroenteritis virus: comparison of reactivity with virulent and attenuated virus	1988		.txt	text/plain	4962	283	56	Twelve hybridomas secreting monoclonal antibodies (MAbs) against Miller virulent strain of transmissible gastroenteritis virus (TGEV) were generated and characterized. Two E 2-specific MAbs had higher neutralizing antibody titers (782 to 34,117) and showed 4-to 13-fold differences in titers against the attenuated and virulent TGEV strains. Two E 2-specific MAbs had higher neutralizing antibody titers (782 to 34,117) and showed 4-to 13-fold differences in titers against the attenuated and virulent TGEV strains. In two previous studies, monoclonal antibodies (MAbs) to the structural proteins of the attenuated (Purdue) strain of TGEV were described [9, 12] . These MAbs were further characterized in various comparative assays including cell culture immunofluorescence, virus neutralization, and radioimmunoprecipitation for reactivity against the Miller virulent and Purdue attenuated strains of TGEV. Anti-E 1 MAbs prepared against a mixture of virulent Miller 3 and Purdue attenuated strains of TGEV had virus neutralizing antibody titers only in the presence of guinea pig, rabbit or swine complement [22] .	./cache/cord-004755-rmnjs1t6.txt	./txt/cord-004755-rmnjs1t6.txt