id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004759-jozdnhgy	Snodgrass, D. R.	Pathogenesis of diarrhoea caused by astrovirus infections in lambs	1979		.txt	text/plain	2304	139	53	Experimental infection of 2-day-old gnotobiotic lambs with lamb astrovirus produced mild diarrhoea after an incubation period of about 48 hours. Astrovirus was not observed in faeces from the lambs killed t4 and 23 hours p.i., but was first seen in the faeces of all other infected lambs between 38 and 48 hours p.i. At necropsy, astrovirus was detected in intestinal contents of all Iambs except that killed 14 hours p.i. The control lambs remained clinically normal, and passed firm brown faeces throughout the duration of the experiment. Specific immunofluorescent staining was detected only in scattered epithelial and subepithelial cells on small intestinal villi (Fig. 1) . Lactase levels in the 6 control lambs were ¢.5±0.5, 5.14-0.6, and 2.44-1.2 units/g tissue for the proximal, mid, and distal small intestinal sites respectively. In midgut of infected lambs, observations were consistently below those of the controls, fMling to a minimum of 1.2 units/g tissue at 23 hours p.i.	./cache/cord-004759-jozdnhgy.txt	./txt/cord-004759-jozdnhgy.txt