id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004812-ikco4h5k	Moore, K. M.	Identification of amino acids involved in a serotype and neutralization specific epitope with in the s1 subunit of avian infectious bronchitis virus	1997-04-06		.txt	text/plain	2731	172	57	title: Identification of amino acids involved in a serotype and neutralization specific epitope with in the s1 subunit of avian infectious bronchitis virus We identified amino acids involved in a serotype specific, conformationally dependent epitope by analysis of the S1 gene of 13 monoclonal antibody-neutralization-resistant mutants. However, based on data obtained using monoclonal antibodies (Mab), there appears to be at least three to ®ve neutralizing, conformationally dependent epitopes on the S1 subunit in different IBV strains [13, 15, 20] . Mab-neutralization-resistant (NR) mutants have been used to identify amino acids (AA) involved in conformationally dependent epitopes in the spike protein of IBV [5, 12] . Based on AA substitutions in Mab-NR mutants, the S1 subunit was divided into three regions associated with neutralizing, conformationally dependent epitopes. In previous research, AA substitutions in IBV Mab-NR mutants were divided into three regions associated with neutralizing epitopes.	./cache/cord-004812-ikco4h5k.txt	./txt/cord-004812-ikco4h5k.txt