id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265768-hwki5lk2	Abi, Keha-mo	An emerging novel bovine coronavirus with a 4-amino-acid insertion in the receptor-binding domain of the hemagglutinin-esterase gene	2020-10-06		.txt	text/plain	1947	91	50	title: An emerging novel bovine coronavirus with a 4-amino-acid insertion in the receptor-binding domain of the hemagglutinin-esterase gene We previously reported a novel recombinant bovine coronavirus (BCoV) strain that was circulating in dairy cattle in China, but this virus was not successfully isolated, and the genetic characteristics of BCoV are still largely unknown. A 3D model constructed based on the crystal structure of bovine coronavirus hemagglutinin-esterase (SMTL ID: 3cl4.1) using the online software SWISSMODEL (https ://www.swiss model .expas y.org/inter activ e) showed that the position of the 4-aa insertion in the R3-loop between F 211 and F 212 in HE in the recombinant BCoV strains would alter the spatial conformation of the receptor-binding site relative to that in the HE recombinant strains and prototype strains lacking this insertion ( Fig. 2B and C) .	./cache/cord-265768-hwki5lk2.txt	./txt/cord-265768-hwki5lk2.txt