id author title date pages extension mime words sentences flesch summary cache txt cord-343131-tu6g977q Cheung, Andrew K. A divergent clade of circular single-stranded DNA viruses from pig feces 2013-04-24 .txt text/plain 1856 108 56 Using metagenomics and molecular cloning methods, we characterized five novel small, circular viral genomes from pig feces that are distantly related to chimpanzee and porcine stool-associated circular viruses, (ChiSCV and PoSCV1). This new clade of viruses, provisionally named porcine stool-associated circular virus 2 and 3 (PoSCV2 and PoSCV3), encodes a stem–loop structure (presumably the origin of DNA replication) in the small intergenic region and a replication initiator protein commonly found in other biological systems that replicate their genomes via the rolling–circle mechanism. The viral genomes can be divided into four regions: two large ORFs with deduced amino acid sequences exhibiting homology to the Rep and Cap of ChiSCV, a LIR that encodes multiple overlapping ORFs, and an SIR that contains a palindromic sequence capable of forming a stem-loop structure. ./cache/cord-343131-tu6g977q.txt ./txt/cord-343131-tu6g977q.txt