id sid tid token lemma pos cord-004775-foaf3vyl 1 1 key key JJ cord-004775-foaf3vyl 2 1 : : : cord-004775-foaf3vyl 2 2 cord-004775-foaf3vyl cord-004775-foaf3vyl NN cord-004775-foaf3vyl 2 3 authors author NNS cord-004775-foaf3vyl 2 4 : : : cord-004775-foaf3vyl 2 5 Weiss Weiss NNP cord-004775-foaf3vyl 2 6 , , , cord-004775-foaf3vyl 2 7 Marianne Marianne NNP cord-004775-foaf3vyl 2 8 ; ; : cord-004775-foaf3vyl 2 9 Horzinek Horzinek NNP cord-004775-foaf3vyl 2 10 , , , cord-004775-foaf3vyl 2 11 M. M. NNP cord-004775-foaf3vyl 2 12 C. C. NNP cord-004775-foaf3vyl 2 13 title title NN cord-004775-foaf3vyl 2 14 : : : cord-004775-foaf3vyl 3 1 The the DT cord-004775-foaf3vyl 3 2 proposed propose VBN cord-004775-foaf3vyl 3 3 family family NN cord-004775-foaf3vyl 3 4 toroviridae toroviridae NN cord-004775-foaf3vyl 3 5 : : : cord-004775-foaf3vyl 3 6 Agents agent NNS cord-004775-foaf3vyl 3 7 of of IN cord-004775-foaf3vyl 3 8 enteric enteric JJ cord-004775-foaf3vyl 3 9 infections infection NNS cord-004775-foaf3vyl 3 10 date date NN cord-004775-foaf3vyl 3 11 : : : cord-004775-foaf3vyl 3 12 1987 1987 CD cord-004775-foaf3vyl 3 13 journal journal NN cord-004775-foaf3vyl 3 14 : : : cord-004775-foaf3vyl 4 1 Arch arch JJ cord-004775-foaf3vyl 4 2 Virol Virol NNP cord-004775-foaf3vyl 4 3 DOI doi NN cord-004775-foaf3vyl 4 4 : : : cord-004775-foaf3vyl 5 1 10.1007 10.1007 CD cord-004775-foaf3vyl 5 2 / / SYM cord-004775-foaf3vyl 5 3 bf01310058 bf01310058 NNP cord-004775-foaf3vyl 5 4 sha sha NNP cord-004775-foaf3vyl 5 5 : : : cord-004775-foaf3vyl 6 1 54e9b322a9b811a947329042a419c89e1ae470ed 54e9b322a9b811a947329042a419c89e1ae470ed CD cord-004775-foaf3vyl 6 2 doc_id doc_id CD cord-004775-foaf3vyl 6 3 : : : cord-004775-foaf3vyl 6 4 4775 4775 CD cord-004775-foaf3vyl 6 5 cord_uid cord_uid NNS cord-004775-foaf3vyl 6 6 : : : cord-004775-foaf3vyl 6 7 foaf3vyl foaf3vyl NN cord-004775-foaf3vyl 7 1 nan nan NNP cord-004775-foaf3vyl 8 1 In in IN cord-004775-foaf3vyl 8 2 1982 1982 CD cord-004775-foaf3vyl 8 3 and and CC cord-004775-foaf3vyl 8 4 1983 1983 CD cord-004775-foaf3vyl 8 5 two two CD cord-004775-foaf3vyl 8 6 new new JJ cord-004775-foaf3vyl 8 7 viruses virus NNS cord-004775-foaf3vyl 8 8 detected detect VBN cord-004775-foaf3vyl 8 9 in in IN cord-004775-foaf3vyl 8 10 fecal fecal JJ cord-004775-foaf3vyl 8 11 material material NN cord-004775-foaf3vyl 8 12 from from IN cord-004775-foaf3vyl 8 13 cattle cattle NNS cord-004775-foaf3vyl 8 14 and and CC cord-004775-foaf3vyl 8 15 horse horse NN cord-004775-foaf3vyl 8 16 , , , cord-004775-foaf3vyl 8 17 respectively respectively RB cord-004775-foaf3vyl 8 18 , , , cord-004775-foaf3vyl 8 19 were be VBD cord-004775-foaf3vyl 8 20 described describe VBN cord-004775-foaf3vyl 8 21 ( ( -LRB- cord-004775-foaf3vyl 8 22 1 1 CD cord-004775-foaf3vyl 8 23 , , , cord-004775-foaf3vyl 8 24 2 2 CD cord-004775-foaf3vyl 8 25 ) ) -RRB- cord-004775-foaf3vyl 8 26 , , , cord-004775-foaf3vyl 8 27 which which WDT cord-004775-foaf3vyl 8 28 could could MD cord-004775-foaf3vyl 8 29 not not RB cord-004775-foaf3vyl 8 30 be be VB cord-004775-foaf3vyl 8 31 assigned assign VBN cord-004775-foaf3vyl 8 32 to to IN cord-004775-foaf3vyl 8 33 any any DT cord-004775-foaf3vyl 8 34 known know VBN cord-004775-foaf3vyl 8 35 virus virus NN cord-004775-foaf3vyl 8 36 family family NN cord-004775-foaf3vyl 8 37 . . . cord-004775-foaf3vyl 9 1 Results result NNS cord-004775-foaf3vyl 9 2 gained gain VBD cord-004775-foaf3vyl 9 3 since since IN cord-004775-foaf3vyl 9 4 then then RB cord-004775-foaf3vyl 9 5 from from IN cord-004775-foaf3vyl 9 6 morphological morphological JJ cord-004775-foaf3vyl 9 7 , , , cord-004775-foaf3vyl 9 8 biochemical biochemical JJ cord-004775-foaf3vyl 9 9 and and CC cord-004775-foaf3vyl 9 10 serological serological JJ cord-004775-foaf3vyl 9 11 studies study NNS cord-004775-foaf3vyl 9 12 demonstrated demonstrate VBD cord-004775-foaf3vyl 9 13 the the DT cord-004775-foaf3vyl 9 14 unique unique JJ cord-004775-foaf3vyl 9 15 t t NN cord-004775-foaf3vyl 9 16 ~ ~ CD cord-004775-foaf3vyl 9 17 atures ature NNS cord-004775-foaf3vyl 9 18 of of IN cord-004775-foaf3vyl 9 19 these these DT cord-004775-foaf3vyl 9 20 viruses virus NNS cord-004775-foaf3vyl 9 21 and and CC cord-004775-foaf3vyl 9 22 justified justify VBD cord-004775-foaf3vyl 9 23 the the DT cord-004775-foaf3vyl 9 24 proposal proposal NN cord-004775-foaf3vyl 9 25 of of IN cord-004775-foaf3vyl 9 26 a a DT cord-004775-foaf3vyl 9 27 new new JJ cord-004775-foaf3vyl 9 28 virus virus NN cord-004775-foaf3vyl 9 29 family family NN cord-004775-foaf3vyl 9 30 , , , cord-004775-foaf3vyl 9 31 provisionally provisionally RB cord-004775-foaf3vyl 9 32 named name VBN cord-004775-foaf3vyl 9 33 " " `` cord-004775-foaf3vyl 9 34 Toroviridae Toroviridae NNP cord-004775-foaf3vyl 9 35 " " '' cord-004775-foaf3vyl 9 36 ( ( -LRB- cord-004775-foaf3vyl 9 37 from from IN cord-004775-foaf3vyl 9 38 latin latin NNP cord-004775-foaf3vyl 9 39 torus= torus= NNP cord-004775-foaf3vyl 9 40 a a DT cord-004775-foaf3vyl 9 41 doughnut doughnut NN cord-004775-foaf3vyl 9 42 shaped shape VBN cord-004775-foaf3vyl 9 43 ring ring NN cord-004775-foaf3vyl 9 44 ) ) -RRB- cord-004775-foaf3vyl 10 1 ( ( -LRB- cord-004775-foaf3vyl 10 2 3 3 CD cord-004775-foaf3vyl 10 3 ) ) -RRB- cord-004775-foaf3vyl 10 4 . . . cord-004775-foaf3vyl 11 1 Berne Berne NNP cord-004775-foaf3vyl 11 2 virus virus NN cord-004775-foaf3vyl 11 3 , , , cord-004775-foaf3vyl 11 4 the the DT cord-004775-foaf3vyl 11 5 best well RBS cord-004775-foaf3vyl 11 6 studied study VBN cord-004775-foaf3vyl 11 7 representative representative NN cord-004775-foaf3vyl 11 8 was be VBD cord-004775-foaf3vyl 11 9 isolated isolate VBN cord-004775-foaf3vyl 11 10 from from IN cord-004775-foaf3vyl 11 11 a a DT cord-004775-foaf3vyl 11 12 rectal rectal JJ cord-004775-foaf3vyl 11 13 swab swab NN cord-004775-foaf3vyl 11 14 of of IN cord-004775-foaf3vyl 11 15 a a DT cord-004775-foaf3vyl 11 16 diarrheic diarrheic NN cord-004775-foaf3vyl 11 17 horse horse NN cord-004775-foaf3vyl 11 18 during during IN cord-004775-foaf3vyl 11 19 routine routine JJ cord-004775-foaf3vyl 11 20 diagnostic diagnostic JJ cord-004775-foaf3vyl 11 21 work work NN cord-004775-foaf3vyl 11 22 in in IN cord-004775-foaf3vyl 11 23 Berne Berne NNP cord-004775-foaf3vyl 11 24 ( ( -LRB- cord-004775-foaf3vyl 11 25 Switzerland Switzerland NNP cord-004775-foaf3vyl 11 26 ) ) -RRB- cord-004775-foaf3vyl 11 27 in in IN cord-004775-foaf3vyl 11 28 1972 1972 CD cord-004775-foaf3vyl 11 29 ( ( -LRB- cord-004775-foaf3vyl 11 30 2 2 CD cord-004775-foaf3vyl 11 31 ) ) -RRB- cord-004775-foaf3vyl 11 32 . . . cord-004775-foaf3vyl 12 1 In in IN cord-004775-foaf3vyl 12 2 1982 1982 CD cord-004775-foaf3vyl 12 3 WOODE WOODE NNP cord-004775-foaf3vyl 12 4 et et NNP cord-004775-foaf3vyl 12 5 at at IN cord-004775-foaf3vyl 12 6 . . . cord-004775-foaf3vyl 13 1 ( ( -LRB- cord-004775-foaf3vyl 13 2 1 1 LS cord-004775-foaf3vyl 13 3 ) ) -RRB- cord-004775-foaf3vyl 13 4 described describe VBD cord-004775-foaf3vyl 13 5 the the DT cord-004775-foaf3vyl 13 6 isolation isolation NN cord-004775-foaf3vyl 13 7 of of IN cord-004775-foaf3vyl 13 8 a a DT cord-004775-foaf3vyl 13 9 virus virus NN cord-004775-foaf3vyl 13 10 during during IN cord-004775-foaf3vyl 13 11 an an DT cord-004775-foaf3vyl 13 12 acute acute JJ cord-004775-foaf3vyl 13 13 epizootie epizootie NN cord-004775-foaf3vyl 13 14 of of IN cord-004775-foaf3vyl 13 15 neonatal neonatal JJ cord-004775-foaf3vyl 13 16 calf calf NN cord-004775-foaf3vyl 13 17 diarrhea diarrhea NN cord-004775-foaf3vyl 13 18 in in IN cord-004775-foaf3vyl 13 19 Breda Breda NNP cord-004775-foaf3vyl 13 20 , , , cord-004775-foaf3vyl 13 21 Iowa Iowa NNP cord-004775-foaf3vyl 13 22 , , , cord-004775-foaf3vyl 13 23 U.S.A. U.S.A. NNP cord-004775-foaf3vyl 14 1 ( ( -LRB- cord-004775-foaf3vyl 14 2 Breda Breda NNP cord-004775-foaf3vyl 14 3 virus virus NN cord-004775-foaf3vyl 14 4 1 1 CD cord-004775-foaf3vyl 14 5 ) ) -RRB- cord-004775-foaf3vyl 14 6 . . . cord-004775-foaf3vyl 15 1 AntigenieMly AntigenieMly NNP cord-004775-foaf3vyl 15 2 related related JJ cord-004775-foaf3vyl 15 3 viruses virus NNS cord-004775-foaf3vyl 15 4 were be VBD cord-004775-foaf3vyl 15 5 later later RB cord-004775-foaf3vyl 15 6 found find VBN cord-004775-foaf3vyl 15 7 in in IN cord-004775-foaf3vyl 15 8 feces fece NNS cord-004775-foaf3vyl 15 9 from from IN cord-004775-foaf3vyl 15 10 a a DT cord-004775-foaf3vyl 15 11 colostrum colostrum NN cord-004775-foaf3vyl 15 12 - - HYPH cord-004775-foaf3vyl 15 13 deprived deprive VBN cord-004775-foaf3vyl 15 14 calf calf NN cord-004775-foaf3vyl 15 15 in in IN cord-004775-foaf3vyl 15 16 Iowa Iowa NNP cord-004775-foaf3vyl 15 17 ( ( -LRB- cord-004775-foaf3vyl 15 18 Breda Breda NNP cord-004775-foaf3vyl 15 19 virus virus NN cord-004775-foaf3vyl 15 20 2 2 CD cord-004775-foaf3vyl 15 21 ) ) -RRB- cord-004775-foaf3vyl 15 22 ( ( -LRB- cord-004775-foaf3vyl 15 23 4 4 LS cord-004775-foaf3vyl 15 24 ) ) -RRB- cord-004775-foaf3vyl 15 25 and and CC cord-004775-foaf3vyl 15 26 from from IN cord-004775-foaf3vyl 15 27 5 5 CD cord-004775-foaf3vyl 15 28 to to TO cord-004775-foaf3vyl 15 29 6 6 CD cord-004775-foaf3vyl 15 30 months month NNS cord-004775-foaf3vyl 15 31 old old JJ cord-004775-foaf3vyl 15 32 diarrheic diarrheic NNS cord-004775-foaf3vyl 15 33 calves calf NNS cord-004775-foaf3vyl 15 34 in in IN cord-004775-foaf3vyl 15 35 Ohio Ohio NNP cord-004775-foaf3vyl 15 36 , , , cord-004775-foaf3vyl 15 37 U.S.A. U.S.A. NNP cord-004775-foaf3vyl 15 38 ( ( -LRB- cord-004775-foaf3vyl 15 39 5 5 CD cord-004775-foaf3vyl 15 40 ) ) -RRB- cord-004775-foaf3vyl 15 41 . . . cord-004775-foaf3vyl 16 1 A a DT cord-004775-foaf3vyl 16 2 morphologically morphologically RB cord-004775-foaf3vyl 16 3 similar similar JJ cord-004775-foaf3vyl 16 4 virus virus NN cord-004775-foaf3vyl 16 5 ( ( -LRB- cord-004775-foaf3vyl 16 6 Lyon Lyon NNP cord-004775-foaf3vyl 16 7 4 4 CD cord-004775-foaf3vyl 16 8 virus virus NN cord-004775-foaf3vyl 16 9 ) ) -RRB- cord-004775-foaf3vyl 16 10 detected detect VBN cord-004775-foaf3vyl 16 11 in in IN cord-004775-foaf3vyl 16 12 cattle cattle NNS cord-004775-foaf3vyl 16 13 in in IN cord-004775-foaf3vyl 16 14 Lyon Lyon NNP cord-004775-foaf3vyl 16 15 , , , cord-004775-foaf3vyl 16 16 France France NNP cord-004775-foaf3vyl 16 17 ( ( -LRB- cord-004775-foaf3vyl 16 18 6 6 CD cord-004775-foaf3vyl 16 19 , , , cord-004775-foaf3vyl 16 20 7 7 CD cord-004775-foaf3vyl 16 21 ) ) -RRB- cord-004775-foaf3vyl 16 22 , , , cord-004775-foaf3vyl 16 23 was be VBD cord-004775-foaf3vyl 16 24 shown show VBN cord-004775-foaf3vyl 16 25 later later RB cord-004775-foaf3vyl 16 26 to to TO cord-004775-foaf3vyl 16 27 possess possess VB cord-004775-foaf3vyl 16 28 an an DT cord-004775-foaf3vyl 16 29 antigenic antigenic JJ cord-004775-foaf3vyl 16 30 relatedness relatedness NN cord-004775-foaf3vyl 16 31 to to IN cord-004775-foaf3vyl 16 32 the the DT cord-004775-foaf3vyl 16 33 Berne Berne NNP cord-004775-foaf3vyl 16 34 ( ( -LRB- cord-004775-foaf3vyl 16 35 BEV BEV NNP cord-004775-foaf3vyl 16 36 ) ) -RRB- cord-004775-foaf3vyl 16 37 and and CC cord-004775-foaf3vyl 16 38 Breda Breda NNP cord-004775-foaf3vyl 16 39 ( ( -LRB- cord-004775-foaf3vyl 16 40 BRV BRV NNP cord-004775-foaf3vyl 16 41 ) ) -RRB- cord-004775-foaf3vyl 16 42 viruses virus NNS cord-004775-foaf3vyl 16 43 . . . cord-004775-foaf3vyl 17 1 BEARDS BEARDS NNP cord-004775-foaf3vyl 17 2 et et NNP cord-004775-foaf3vyl 17 3 al al NNP cord-004775-foaf3vyl 17 4 . . . cord-004775-foaf3vyl 18 1 ( ( -LRB- cord-004775-foaf3vyl 18 2 8) 8) NNP cord-004775-foaf3vyl 18 3 reported report VBD cord-004775-foaf3vyl 18 4 in in IN cord-004775-foaf3vyl 18 5 1984 1984 CD cord-004775-foaf3vyl 18 6 particles particle NNS cord-004775-foaf3vyl 18 7 resembling resemble VBG cord-004775-foaf3vyl 18 8 BEV BEV NNP cord-004775-foaf3vyl 18 9 and and CC cord-004775-foaf3vyl 18 10 BRV BRV NNP cord-004775-foaf3vyl 18 11 in in IN cord-004775-foaf3vyl 18 12 stool stool NN cord-004775-foaf3vyl 18 13 specimens specimen NNS cord-004775-foaf3vyl 18 14 of of IN cord-004775-foaf3vyl 18 15 children child NNS cord-004775-foaf3vyl 18 16 and and CC cord-004775-foaf3vyl 18 17 adults adult NNS cord-004775-foaf3vyl 18 18 with with IN cord-004775-foaf3vyl 18 19 diarrhea diarrhea NN cord-004775-foaf3vyl 18 20 , , , cord-004775-foaf3vyl 18 21 which which WDT cord-004775-foaf3vyl 18 22 reacted react VBD cord-004775-foaf3vyl 18 23 with with IN cord-004775-foaf3vyl 18 24 antibodies antibody NNS cord-004775-foaf3vyl 18 25 against against IN cord-004775-foaf3vyl 18 26 BEV BEV NNP cord-004775-foaf3vyl 18 27 and and CC cord-004775-foaf3vyl 18 28 BRV BRV NNP cord-004775-foaf3vyl 18 29 in in IN cord-004775-foaf3vyl 18 30 immunoelectron immunoelectron NNP cord-004775-foaf3vyl 18 31 microscopy microscopy NNP cord-004775-foaf3vyl 18 32 . . . cord-004775-foaf3vyl 19 1 Similar similar JJ cord-004775-foaf3vyl 19 2 particles particle NNS cord-004775-foaf3vyl 19 3 were be VBD cord-004775-foaf3vyl 19 4 seen see VBN cord-004775-foaf3vyl 19 5 by by IN cord-004775-foaf3vyl 19 6 Schaap Schaap NNP cord-004775-foaf3vyl 19 7 in in IN cord-004775-foaf3vyl 19 8 feces fece NNS cord-004775-foaf3vyl 19 9 of of IN cord-004775-foaf3vyl 19 10 children child NNS cord-004775-foaf3vyl 19 11 with with IN cord-004775-foaf3vyl 19 12 gastroenteritis gastroenteritis NN cord-004775-foaf3vyl 19 13 in in IN cord-004775-foaf3vyl 19 14 Rotterdam Rotterdam NNP cord-004775-foaf3vyl 19 15 ( ( -LRB- cord-004775-foaf3vyl 19 16 3 3 CD cord-004775-foaf3vyl 19 17 ) ) -RRB- cord-004775-foaf3vyl 19 18 . . . cord-004775-foaf3vyl 20 1 Consequently consequently RB cord-004775-foaf3vyl 20 2 , , , cord-004775-foaf3vyl 20 3 members member NNS cord-004775-foaf3vyl 20 4 of of IN cord-004775-foaf3vyl 20 5 the the DT cord-004775-foaf3vyl 20 6 torovirus torovirus NNP cord-004775-foaf3vyl 20 7 family family NN cord-004775-foaf3vyl 20 8 presently presently RB cord-004775-foaf3vyl 20 9 recognized recognize VBN cord-004775-foaf3vyl 20 10 are be VBP cord-004775-foaf3vyl 20 11 enteric enteric JJ cord-004775-foaf3vyl 20 12 viruses virus NNS cord-004775-foaf3vyl 20 13 from from IN cord-004775-foaf3vyl 20 14 three three CD cord-004775-foaf3vyl 20 15 different different JJ cord-004775-foaf3vyl 20 16 , , , cord-004775-foaf3vyl 20 17 species specie NNS cord-004775-foaf3vyl 20 18 . . . cord-004775-foaf3vyl 21 1 From from IN cord-004775-foaf3vyl 21 2 serological serological JJ cord-004775-foaf3vyl 21 3 studies study NNS cord-004775-foaf3vyl 21 4 , , , cord-004775-foaf3vyl 21 5 however however RB cord-004775-foaf3vyl 21 6 , , , cord-004775-foaf3vyl 21 7 the the DT cord-004775-foaf3vyl 21 8 presence presence NN cord-004775-foaf3vyl 21 9 of of IN cord-004775-foaf3vyl 21 10 toroviruses toroviruses NNP cord-004775-foaf3vyl 21 11 in in IN cord-004775-foaf3vyl 21 12 other other JJ cord-004775-foaf3vyl 21 13 animals animal NNS cord-004775-foaf3vyl 21 14 became become VBD cord-004775-foaf3vyl 21 15 evident evident JJ cord-004775-foaf3vyl 21 16 . . . cord-004775-foaf3vyl 22 1 This this DT cord-004775-foaf3vyl 22 2 review review NN cord-004775-foaf3vyl 22 3 summarizes summarize VBZ cord-004775-foaf3vyl 22 4 the the DT cord-004775-foaf3vyl 22 5 current current JJ cord-004775-foaf3vyl 22 6 knowledge knowledge NN cord-004775-foaf3vyl 22 7 of of IN cord-004775-foaf3vyl 22 8 the the DT cord-004775-foaf3vyl 22 9 properties property NNS cord-004775-foaf3vyl 22 10 of of IN cord-004775-foaf3vyl 22 11 this this DT cord-004775-foaf3vyl 22 12 new new JJ cord-004775-foaf3vyl 22 13 group group NN cord-004775-foaf3vyl 22 14 of of IN cord-004775-foaf3vyl 22 15 viruses virus NNS cord-004775-foaf3vyl 22 16 . . . cord-004775-foaf3vyl 23 1 In in IN cord-004775-foaf3vyl 23 2 negatively negatively RB cord-004775-foaf3vyl 23 3 stained stain VBN cord-004775-foaf3vyl 23 4 preparations preparation NNS cord-004775-foaf3vyl 23 5 toroviruses toroviruse NNS cord-004775-foaf3vyl 23 6 are be VBP cord-004775-foaf3vyl 23 7 pleomorphic pleomorphic JJ cord-004775-foaf3vyl 23 8 and and CC cord-004775-foaf3vyl 23 9 measure measure VB cord-004775-foaf3vyl 23 10 120 120 CD cord-004775-foaf3vyl 23 11 to to TO cord-004775-foaf3vyl 23 12 140 140 CD cord-004775-foaf3vyl 23 13 nm nm NN cord-004775-foaf3vyl 23 14 in in IN cord-004775-foaf3vyl 23 15 their -PRON- PRP$ cord-004775-foaf3vyl 23 16 largest large JJS cord-004775-foaf3vyl 23 17 diameter diameter NN cord-004775-foaf3vyl 23 18 . . . cord-004775-foaf3vyl 24 1 They -PRON- PRP cord-004775-foaf3vyl 24 2 were be VBD cord-004775-foaf3vyl 24 3 described describe VBN cord-004775-foaf3vyl 24 4 as as IN cord-004775-foaf3vyl 24 5 spherical spherical JJ cord-004775-foaf3vyl 24 6 , , , cord-004775-foaf3vyl 24 7 oval oval JJ cord-004775-foaf3vyl 24 8 , , , cord-004775-foaf3vyl 24 9 elongated elongated JJ cord-004775-foaf3vyl 24 10 or or CC cord-004775-foaf3vyl 24 11 kidney kidney NN cord-004775-foaf3vyl 24 12 - - HYPH cord-004775-foaf3vyl 24 13 shaped shape VBN cord-004775-foaf3vyl 24 14 particles particle NNS cord-004775-foaf3vyl 24 15 ( ( -LRB- cord-004775-foaf3vyl 24 16 Fig Fig NNP cord-004775-foaf3vyl 24 17 . . . cord-004775-foaf3vyl 24 18 l l NN cord-004775-foaf3vyl 24 19 ) ) -RRB- cord-004775-foaf3vyl 24 20 consisting consist VBG cord-004775-foaf3vyl 24 21 of of IN cord-004775-foaf3vyl 24 22 " " `` cord-004775-foaf3vyl 24 23 a a DT cord-004775-foaf3vyl 24 24 peplomer peplomer NN cord-004775-foaf3vyl 24 25 - - HYPH cord-004775-foaf3vyl 24 26 bearing bear VBG cord-004775-foaf3vyl 24 27 envelope envelope NN cord-004775-foaf3vyl 24 28 and and CC cord-004775-foaf3vyl 24 29 a a DT cord-004775-foaf3vyl 24 30 sausage sausage NN cord-004775-foaf3vyl 24 31 - - HYPH cord-004775-foaf3vyl 24 32 like like JJ cord-004775-foaf3vyl 24 33 internal internal JJ cord-004775-foaf3vyl 24 34 structure structure NN cord-004775-foaf3vyl 24 35 with with IN cord-004775-foaf3vyl 24 36 transverse transverse JJ cord-004775-foaf3vyl 24 37 striation striation NN cord-004775-foaf3vyl 24 38 ( ( -LRB- cord-004775-foaf3vyl 24 39 estimated estimate VBN cord-004775-foaf3vyl 24 40 periodicity periodicity NN cord-004775-foaf3vyl 24 41 about about IN cord-004775-foaf3vyl 24 42 4.5 4.5 CD cord-004775-foaf3vyl 24 43 nm nm CD cord-004775-foaf3vyl 24 44 ) ) -RRB- cord-004775-foaf3vyl 24 45 ( ( -LRB- cord-004775-foaf3vyl 24 46 1 1 CD cord-004775-foaf3vyl 24 47 , , , cord-004775-foaf3vyl 24 48 2 2 CD cord-004775-foaf3vyl 24 49 ) ) -RRB- cord-004775-foaf3vyl 24 50 . . . cord-004775-foaf3vyl 25 1 BEV BEV NNP cord-004775-foaf3vyl 25 2 projections projection NNS cord-004775-foaf3vyl 25 3 measure measure VBP cord-004775-foaf3vyl 25 4 20 20 CD cord-004775-foaf3vyl 25 5 nm nm NN cord-004775-foaf3vyl 25 6 in in IN cord-004775-foaf3vyl 25 7 length length NN cord-004775-foaf3vyl 25 8 . . . cord-004775-foaf3vyl 26 1 They -PRON- PRP cord-004775-foaf3vyl 26 2 have have VBP cord-004775-foaf3vyl 26 3 a a DT cord-004775-foaf3vyl 26 4 drumstick drumstick NN cord-004775-foaf3vyl 26 5 shape shape NN cord-004775-foaf3vyl 26 6 and and CC cord-004775-foaf3vyl 26 7 consist consist VBP cord-004775-foaf3vyl 26 8 of of IN cord-004775-foaf3vyl 26 9 a a DT cord-004775-foaf3vyl 26 10 thin thin JJ cord-004775-foaf3vyl 26 11 stalk stalk NN cord-004775-foaf3vyl 26 12 carrying carry VBG cord-004775-foaf3vyl 26 13 a a DT cord-004775-foaf3vyl 26 14 distal distal JJ cord-004775-foaf3vyl 26 15 sphcrule sphcrule NNP cord-004775-foaf3vyl 26 16 ( ( -LRB- cord-004775-foaf3vyl 26 17 2 2 CD cord-004775-foaf3vyl 26 18 ) ) -RRB- cord-004775-foaf3vyl 26 19 . . . cord-004775-foaf3vyl 27 1 BRV BRV NNP cord-004775-foaf3vyl 27 2 were be VBD cord-004775-foaf3vyl 27 3 described describe VBN cord-004775-foaf3vyl 27 4 to to TO cord-004775-foaf3vyl 27 5 possess possess VB cord-004775-foaf3vyl 27 6 7.6 7.6 CD cord-004775-foaf3vyl 27 7 - - SYM cord-004775-foaf3vyl 27 8 9.5 9.5 CD cord-004775-foaf3vyl 27 9 nm nm NNP cord-004775-foaf3vyl 27 10 pcplomers pcplomer NNS cord-004775-foaf3vyl 27 11 ; ; : cord-004775-foaf3vyl 27 12 few few JJ cord-004775-foaf3vyl 27 13 particles particle NNS cord-004775-foaf3vyl 27 14 showed show VBD cord-004775-foaf3vyl 27 15 irregularly irregularly RB cord-004775-foaf3vyl 27 16 arranged arrange VBN cord-004775-foaf3vyl 27 17 processes process NNS cord-004775-foaf3vyl 27 18 of of IN cord-004775-foaf3vyl 27 19 17 17 CD cord-004775-foaf3vyl 27 20 - - SYM cord-004775-foaf3vyl 27 21 24 24 CD cord-004775-foaf3vyl 27 22 nm nm NN cord-004775-foaf3vyl 27 23 thought think VBN cord-004775-foaf3vyl 27 24 by by IN cord-004775-foaf3vyl 27 25 WOODE WOODE NNP cord-004775-foaf3vyl 27 26 et et NNP cord-004775-foaf3vyl 27 27 al al NNP cord-004775-foaf3vyl 27 28 . . . cord-004775-foaf3vyl 28 1 to to TO cord-004775-foaf3vyl 28 2 represent represent VB cord-004775-foaf3vyl 28 3 tissue tissue NN cord-004775-foaf3vyl 28 4 debris debris NN cord-004775-foaf3vyl 28 5 ( ( -LRB- cord-004775-foaf3vyl 28 6 1 1 CD cord-004775-foaf3vyl 28 7 ) ) -RRB- cord-004775-foaf3vyl 28 8 . . . cord-004775-foaf3vyl 29 1 The the DT cord-004775-foaf3vyl 29 2 longer long JJR cord-004775-foaf3vyl 29 3 peplomers peplomer NNS cord-004775-foaf3vyl 29 4 were be VBD cord-004775-foaf3vyl 29 5 more more RBR cord-004775-foaf3vyl 29 6 frequently frequently RB cord-004775-foaf3vyl 29 7 seen see VBN cord-004775-foaf3vyl 29 8 in in IN cord-004775-foaf3vyl 29 9 BRV BRV NNP cord-004775-foaf3vyl 29 10 2 2 CD cord-004775-foaf3vyl 29 11 than than IN cord-004775-foaf3vyl 29 12 BRV BRV NNP cord-004775-foaf3vyl 29 13 1 1 CD cord-004775-foaf3vyl 29 14 preparations preparation NNS cord-004775-foaf3vyl 29 15 . . . cord-004775-foaf3vyl 30 1 Particles particle NNS cord-004775-foaf3vyl 30 2 from from IN cord-004775-foaf3vyl 30 3 human human JJ cord-004775-foaf3vyl 30 4 feces fece NNS cord-004775-foaf3vyl 30 5 were be VBD cord-004775-foaf3vyl 30 6 surrounded surround VBN cord-004775-foaf3vyl 30 7 by by IN cord-004775-foaf3vyl 30 8 a a DT cord-004775-foaf3vyl 30 9 halo halo NN cord-004775-foaf3vyl 30 10 of of IN cord-004775-foaf3vyl 30 11 7 7 CD cord-004775-foaf3vyl 30 12 -9 -9 NN cord-004775-foaf3vyl 30 13 nm nm NN cord-004775-foaf3vyl 30 14 projections projection NNS cord-004775-foaf3vyl 30 15 ; ; : cord-004775-foaf3vyl 30 16 occasionally occasionally RB cord-004775-foaf3vyl 30 17 a a DT cord-004775-foaf3vyl 30 18 second second JJ cord-004775-foaf3vyl 30 19 ring ring NN cord-004775-foaf3vyl 30 20 of of IN cord-004775-foaf3vyl 30 21 small small JJ cord-004775-foaf3vyl 30 22 peplomers peplomer NNS cord-004775-foaf3vyl 30 23 was be VBD cord-004775-foaf3vyl 30 24 noticed notice VBN cord-004775-foaf3vyl 30 25 , , , cord-004775-foaf3vyl 30 26 partly partly RB cord-004775-foaf3vyl 30 27 superimposed superimpose VBN cord-004775-foaf3vyl 30 28 upon upon IN cord-004775-foaf3vyl 30 29 the the DT cord-004775-foaf3vyl 30 30 first first JJ cord-004775-foaf3vyl 30 31 . . . cord-004775-foaf3vyl 31 1 Longer long JJR cord-004775-foaf3vyl 31 2 projections projection NNS cord-004775-foaf3vyl 31 3 were be VBD cord-004775-foaf3vyl 31 4 only only RB cord-004775-foaf3vyl 31 5 occasionally occasionally RB cord-004775-foaf3vyl 31 6 observed observe VBN cord-004775-foaf3vyl 31 7 ( ( -LRB- cord-004775-foaf3vyl 31 8 8) 8) NN cord-004775-foaf3vyl 31 9 . . . cord-004775-foaf3vyl 32 1 In in IN cord-004775-foaf3vyl 32 2 thin thin JJ cord-004775-foaf3vyl 32 3 sections section NNS cord-004775-foaf3vyl 32 4 through through IN cord-004775-foaf3vyl 32 5 BEV BEV NNP cord-004775-foaf3vyl 32 6 infected infect VBN cord-004775-foaf3vyl 32 7 cells cell NNS cord-004775-foaf3vyl 32 8 ( ( -LRB- cord-004775-foaf3vyl 32 9 horse horse NN cord-004775-foaf3vyl 32 10 kidney kidney NN cord-004775-foaf3vyl 32 11 , , , cord-004775-foaf3vyl 32 12 embryonic embryonic JJ cord-004775-foaf3vyl 32 13 mule mule JJ cord-004775-foaf3vyl 32 14 skin skin NN cord-004775-foaf3vyl 32 15 , , , cord-004775-foaf3vyl 32 16 equine equine JJ cord-004775-foaf3vyl 32 17 dermal dermal JJ cord-004775-foaf3vyl 32 18 cells cell NNS cord-004775-foaf3vyl 32 19 ) ) -RRB- cord-004775-foaf3vyl 32 20 densely densely RB cord-004775-foaf3vyl 32 21 staining stain VBG cord-004775-foaf3vyl 32 22 spherical spherical JJ cord-004775-foaf3vyl 32 23 , , , cord-004775-foaf3vyl 32 24 elliptieM elliptieM NNP cord-004775-foaf3vyl 32 25 and and CC cord-004775-foaf3vyl 32 26 elongated elongated JJ cord-004775-foaf3vyl 32 27 particles particle NNS cord-004775-foaf3vyl 32 28 were be VBD cord-004775-foaf3vyl 32 29 detected detect VBN cord-004775-foaf3vyl 32 30 ( ( -LRB- cord-004775-foaf3vyl 32 31 2 2 CD cord-004775-foaf3vyl 32 32 , , , cord-004775-foaf3vyl 32 33 9 9 CD cord-004775-foaf3vyl 32 34 ) ) -RRB- cord-004775-foaf3vyl 32 35 . . . cord-004775-foaf3vyl 33 1 A a DT cord-004775-foaf3vyl 33 2 clear clear JJ cord-004775-foaf3vyl 33 3 distinction distinction NN cord-004775-foaf3vyl 33 4 between between IN cord-004775-foaf3vyl 33 5 an an DT cord-004775-foaf3vyl 33 6 inner inner JJ cord-004775-foaf3vyl 33 7 structure structure NN cord-004775-foaf3vyl 33 8 of of IN cord-004775-foaf3vyl 33 9 high high JJ cord-004775-foaf3vyl 33 10 electron electron NN cord-004775-foaf3vyl 33 11 density density NN cord-004775-foaf3vyl 33 12 , , , cord-004775-foaf3vyl 33 13 apparently apparently RB cord-004775-foaf3vyl 33 14 corresponding correspond VBG cord-004775-foaf3vyl 33 15 to to IN cord-004775-foaf3vyl 33 16 the the DT cord-004775-foaf3vyl 33 17 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 33 18 , , , cord-004775-foaf3vyl 33 19 and and CC cord-004775-foaf3vyl 33 20 a a DT cord-004775-foaf3vyl 33 21 less less RBR cord-004775-foaf3vyl 33 22 dense dense JJ cord-004775-foaf3vyl 33 23 outer outer JJ cord-004775-foaf3vyl 33 24 region region NN cord-004775-foaf3vyl 33 25 can can MD cord-004775-foaf3vyl 33 26 be be VB cord-004775-foaf3vyl 33 27 made make VBN cord-004775-foaf3vyl 33 28 . . . cord-004775-foaf3vyl 34 1 Spherical spherical JJ cord-004775-foaf3vyl 34 2 and and CC cord-004775-foaf3vyl 34 3 elliptical elliptical JJ cord-004775-foaf3vyl 34 4 particles particle NNS cord-004775-foaf3vyl 34 5 enclosing enclose VBG cord-004775-foaf3vyl 34 6 a a DT cord-004775-foaf3vyl 34 7 crescent crescent NN cord-004775-foaf3vyl 34 8 - - HYPH cord-004775-foaf3vyl 34 9 shaped shape VBN cord-004775-foaf3vyl 34 10 core core NN cord-004775-foaf3vyl 34 11 are be VBP cord-004775-foaf3vyl 34 12 prevalent prevalent JJ cord-004775-foaf3vyl 34 13 in in IN cord-004775-foaf3vyl 34 14 the the DT cord-004775-foaf3vyl 34 15 extracellular extracellular JJ cord-004775-foaf3vyl 34 16 space space NN cord-004775-foaf3vyl 34 17 . . . cord-004775-foaf3vyl 35 1 Enveloped envelop VBN cord-004775-foaf3vyl 35 2 twin twin JJ cord-004775-foaf3vyl 35 3 circular circular JJ cord-004775-foaf3vyl 35 4 structures structure NNS cord-004775-foaf3vyl 35 5 with with IN cord-004775-foaf3vyl 35 6 a a DT cord-004775-foaf3vyl 35 7 light light JJ cord-004775-foaf3vyl 35 8 centre centre NN cord-004775-foaf3vyl 35 9 are be VBP cord-004775-foaf3vyl 35 10 interpreted interpret VBN cord-004775-foaf3vyl 35 11 as as IN cord-004775-foaf3vyl 35 12 cross cross NN cord-004775-foaf3vyl 35 13 - - NNS cord-004775-foaf3vyl 35 14 sections section NNS cord-004775-foaf3vyl 35 15 through through IN cord-004775-foaf3vyl 35 16 virions virion NNS cord-004775-foaf3vyl 35 17 containing contain VBG cord-004775-foaf3vyl 35 18 a a DT cord-004775-foaf3vyl 35 19 hollow hollow JJ cord-004775-foaf3vyl 35 20 tubular tubular JJ cord-004775-foaf3vyl 35 21 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 35 22 bent bent JJ cord-004775-foaf3vyl 35 23 into into IN cord-004775-foaf3vyl 35 24 an an DT cord-004775-foaf3vyl 35 25 open open JJ cord-004775-foaf3vyl 35 26 torus torus NN cord-004775-foaf3vyl 35 27 ( ( -LRB- cord-004775-foaf3vyl 35 28 Fig fig NN cord-004775-foaf3vyl 35 29 . . NNP cord-004775-foaf3vyl 35 30 2 2 CD cord-004775-foaf3vyl 35 31 ) ) -RRB- cord-004775-foaf3vyl 35 32 . . . cord-004775-foaf3vyl 36 1 Bacilliform Bacilliform NNS cord-004775-foaf3vyl 36 2 viruses virus NNS cord-004775-foaf3vyl 36 3 with with IN cord-004775-foaf3vyl 36 4 a a DT cord-004775-foaf3vyl 36 5 rodlike rodlike JJ cord-004775-foaf3vyl 36 6 core core NN cord-004775-foaf3vyl 36 7 are be VBP cord-004775-foaf3vyl 36 8 On on IN cord-004775-foaf3vyl 36 9 the the DT cord-004775-foaf3vyl 36 10 right right JJ cord-004775-foaf3vyl 36 11 electron electron NN cord-004775-foaf3vyl 36 12 mierographs mierographs NN cord-004775-foaf3vyl 36 13 of of IN cord-004775-foaf3vyl 36 14 BEV BEV NNP cord-004775-foaf3vyl 36 15 particles particle NNS cord-004775-foaf3vyl 36 16 , , , cord-004775-foaf3vyl 36 17 on on IN cord-004775-foaf3vyl 36 18 the the DT cord-004775-foaf3vyl 36 19 left left JJ cord-004775-foaf3vyl 36 20 schematic schematic JJ cord-004775-foaf3vyl 36 21 interpretations interpretation NNS cord-004775-foaf3vyl 36 22 of of IN cord-004775-foaf3vyl 36 23 the the DT cord-004775-foaf3vyl 36 24 viral viral JJ cord-004775-foaf3vyl 36 25 structures structure NNS cord-004775-foaf3vyl 36 26 seen see VBN cord-004775-foaf3vyl 36 27 in in IN cord-004775-foaf3vyl 36 28 the the DT cord-004775-foaf3vyl 36 29 corresponding correspond VBG cord-004775-foaf3vyl 36 30 photographs photograph NNS cord-004775-foaf3vyl 36 31 are be VBP cord-004775-foaf3vyl 36 32 shown show VBN cord-004775-foaf3vyl 36 33 , , , cord-004775-foaf3vyl 36 34 a a DT cord-004775-foaf3vyl 36 35 Virion virion NN cord-004775-foaf3vyl 36 36 with with IN cord-004775-foaf3vyl 36 37 a a DT cord-004775-foaf3vyl 36 38 toroidal toroidal JJ cord-004775-foaf3vyl 36 39 core core NN cord-004775-foaf3vyl 36 40 within within IN cord-004775-foaf3vyl 36 41 a a DT cord-004775-foaf3vyl 36 42 circular circular JJ cord-004775-foaf3vyl 36 43 particle particle NN cord-004775-foaf3vyl 36 44 out out RP cord-004775-foaf3vyl 36 45 , , , cord-004775-foaf3vyl 36 46 line line NN cord-004775-foaf3vyl 36 47 . . . cord-004775-foaf3vyl 37 1 The the DT cord-004775-foaf3vyl 37 2 indicated indicate VBN cord-004775-foaf3vyl 37 3 section section NN cord-004775-foaf3vyl 37 4 plane plane NN cord-004775-foaf3vyl 37 5 1 1 CD cord-004775-foaf3vyl 37 6 leeds leeds NNP cord-004775-foaf3vyl 37 7 to to IN cord-004775-foaf3vyl 37 8 a a DT cord-004775-foaf3vyl 37 9 biconcave biconcave NN cord-004775-foaf3vyl 37 10 structure structure NN cord-004775-foaf3vyl 37 11 with with IN cord-004775-foaf3vyl 37 12 twin twin JJ cord-004775-foaf3vyl 37 13 circular circular JJ cord-004775-foaf3vyl 37 14 cross cross NN cord-004775-foaf3vyl 37 15 - - NNS cord-004775-foaf3vyl 37 16 sections section NNS cord-004775-foaf3vyl 37 17 of of IN cord-004775-foaf3vyl 37 18 the the DT cord-004775-foaf3vyl 37 19 core core NN cord-004775-foaf3vyl 37 20 , , , cord-004775-foaf3vyl 37 21 b. b. NNP cord-004775-foaf3vyl 37 22 Section Section NNP cord-004775-foaf3vyl 37 23 plane plane NN cord-004775-foaf3vyl 37 24 2 2 CD cord-004775-foaf3vyl 37 25 cuts cut VBZ cord-004775-foaf3vyl 37 26 the the DT cord-004775-foaf3vyl 37 27 nueleocapsid nueleocapsid NN cord-004775-foaf3vyl 37 28 only only RB cord-004775-foaf3vyl 37 29 once once RB cord-004775-foaf3vyl 37 30 , , , cord-004775-foaf3vyl 37 31 c. c. NNP cord-004775-foaf3vyl 37 32 d d NNP cord-004775-foaf3vyl 37 33 Elliptical Elliptical NNP cord-004775-foaf3vyl 37 34 virion virion NN cord-004775-foaf3vyl 37 35 with with IN cord-004775-foaf3vyl 37 36 little little JJ cord-004775-foaf3vyl 37 37 resolution resolution NN cord-004775-foaf3vyl 37 38 of of IN cord-004775-foaf3vyl 37 39 the the DT cord-004775-foaf3vyl 37 40 interior interior NN cord-004775-foaf3vyl 37 41 , , , cord-004775-foaf3vyl 37 42 e e NNP cord-004775-foaf3vyl 37 43 Rod rod NN cord-004775-foaf3vyl 37 44 - - HYPH cord-004775-foaf3vyl 37 45 shaped shape VBN cord-004775-foaf3vyl 37 46 particle particle NN cord-004775-foaf3vyl 37 47 , , , cord-004775-foaf3vyl 37 48 f f NNP cord-004775-foaf3vyl 37 49 Circular circular JJ cord-004775-foaf3vyl 37 50 structure structure NN cord-004775-foaf3vyl 37 51 with with IN cord-004775-foaf3vyl 37 52 an an DT cord-004775-foaf3vyl 37 53 electron electron NN cord-004775-foaf3vyl 37 54 - - HYPH cord-004775-foaf3vyl 37 55 lucent lucent NN cord-004775-foaf3vyl 37 56 center center NN cord-004775-foaf3vyl 37 57 corresponding correspond VBG cord-004775-foaf3vyl 37 58 to to IN cord-004775-foaf3vyl 37 59 ~ ~ ADD cord-004775-foaf3vyl 37 60 cross cross NN cord-004775-foaf3vyl 37 61 - - NN cord-004775-foaf3vyl 37 62 section section NN cord-004775-foaf3vyl 37 63 through through IN cord-004775-foaf3vyl 37 64 a a DT cord-004775-foaf3vyl 37 65 rod rod NN cord-004775-foaf3vyl 37 66 - - HYPH cord-004775-foaf3vyl 37 67 shaped shape VBN cord-004775-foaf3vyl 37 68 particle particle NN cord-004775-foaf3vyl 37 69 , , , cord-004775-foaf3vyl 37 70 g g NNP cord-004775-foaf3vyl 37 71 Virion Virion NNP cord-004775-foaf3vyl 37 72 with with IN cord-004775-foaf3vyl 37 73 a a DT cord-004775-foaf3vyl 37 74 C c NN cord-004775-foaf3vyl 37 75 - - HYPH cord-004775-foaf3vyl 37 76 shaped shape VBN cord-004775-foaf3vyl 37 77 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 37 78 ; ; : cord-004775-foaf3vyl 37 79 in in IN cord-004775-foaf3vyl 37 80 contrast contrast NN cord-004775-foaf3vyl 37 81 to to IN cord-004775-foaf3vyl 37 82 a a DT cord-004775-foaf3vyl 37 83 the the DT cord-004775-foaf3vyl 37 84 envelope envelope NN cord-004775-foaf3vyl 37 85 follows follow VBZ cord-004775-foaf3vyl 37 86 the the DT cord-004775-foaf3vyl 37 87 smaller small JJR cord-004775-foaf3vyl 37 88 curvature curvature NN cord-004775-foaf3vyl 37 89 of of IN cord-004775-foaf3vyl 37 90 the the DT cord-004775-foaf3vyl 37 91 torus torus NN cord-004775-foaf3vyl 37 92 , , , cord-004775-foaf3vyl 37 93 h h NNP cord-004775-foaf3vyl 37 94 Cross Cross NNP cord-004775-foaf3vyl 37 95 - - HYPH cord-004775-foaf3vyl 37 96 section section NN cord-004775-foaf3vyl 37 97 through through IN cord-004775-foaf3vyl 37 98 g g NN cord-004775-foaf3vyl 37 99 cutting cut VBG cord-004775-foaf3vyl 37 100 the the DT cord-004775-foaf3vyl 37 101 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 37 102 twice twice RB cord-004775-foaf3vyl 37 103 encountered encounter VBN cord-004775-foaf3vyl 37 104 in in IN cord-004775-foaf3vyl 37 105 cytoplasmic cytoplasmic JJ cord-004775-foaf3vyl 37 106 vacuoles vacuole NNS cord-004775-foaf3vyl 37 107 . . . cord-004775-foaf3vyl 38 1 Cross cross NN cord-004775-foaf3vyl 38 2 - - NNS cord-004775-foaf3vyl 38 3 sections section NNS cord-004775-foaf3vyl 38 4 through through IN cord-004775-foaf3vyl 38 5 these these DT cord-004775-foaf3vyl 38 6 rod rod NN cord-004775-foaf3vyl 38 7 - - HYPH cord-004775-foaf3vyl 38 8 like like JJ cord-004775-foaf3vyl 38 9 particles particle NNS cord-004775-foaf3vyl 38 10 revealed reveal VBD cord-004775-foaf3vyl 38 11 three three CD cord-004775-foaf3vyl 38 12 concentric concentric JJ cord-004775-foaf3vyl 38 13 circles circle NNS cord-004775-foaf3vyl 38 14 of of IN cord-004775-foaf3vyl 38 15 high high JJ cord-004775-foaf3vyl 38 16 electron electron NN cord-004775-foaf3vyl 38 17 density density NN cord-004775-foaf3vyl 38 18 . . . cord-004775-foaf3vyl 39 1 The the DT cord-004775-foaf3vyl 39 2 outer outer JJ cord-004775-foaf3vyl 39 3 circles circle NNS cord-004775-foaf3vyl 39 4 measured measure VBD cord-004775-foaf3vyl 39 5 47 47 CD cord-004775-foaf3vyl 39 6 and and CC cord-004775-foaf3vyl 39 7 37 37 CD cord-004775-foaf3vyl 39 8 nm nm NN cord-004775-foaf3vyl 39 9 , , , cord-004775-foaf3vyl 39 10 respectively respectively RB cord-004775-foaf3vyl 39 11 , , , cord-004775-foaf3vyl 39 12 in in IN cord-004775-foaf3vyl 39 13 diameter diameter NN cord-004775-foaf3vyl 39 14 . . . cord-004775-foaf3vyl 40 1 The the DT cord-004775-foaf3vyl 40 2 innermost innermost JJS cord-004775-foaf3vyl 40 3 circle circle NN cord-004775-foaf3vyl 40 4 of of IN cord-004775-foaf3vyl 40 5 highest high JJS cord-004775-foaf3vyl 40 6 electron electron NN cord-004775-foaf3vyl 40 7 density density NN cord-004775-foaf3vyl 40 8 ( ( -LRB- cord-004775-foaf3vyl 40 9 diameter diameter NN cord-004775-foaf3vyl 40 10 24 24 CD cord-004775-foaf3vyl 40 11 nm nm NN cord-004775-foaf3vyl 40 12 ) ) -RRB- cord-004775-foaf3vyl 40 13 is be VBZ cord-004775-foaf3vyl 40 14 thought think VBN cord-004775-foaf3vyl 40 15 to to TO cord-004775-foaf3vyl 40 16 represent represent VB cord-004775-foaf3vyl 40 17 a a DT cord-004775-foaf3vyl 40 18 transversal transversal JJ cord-004775-foaf3vyl 40 19 section section NN cord-004775-foaf3vyl 40 20 through through IN cord-004775-foaf3vyl 40 21 the the DT cord-004775-foaf3vyl 40 22 nueleoeapsid nueleoeapsid NN cord-004775-foaf3vyl 40 23 . . . cord-004775-foaf3vyl 41 1 Its -PRON- PRP$ cord-004775-foaf3vyl 41 2 electron electron NN cord-004775-foaf3vyl 41 3 lucent lucent NN cord-004775-foaf3vyl 41 4 centre centre NN cord-004775-foaf3vyl 41 5 is be VBZ cord-004775-foaf3vyl 41 6 indicative indicative JJ cord-004775-foaf3vyl 41 7 for for IN cord-004775-foaf3vyl 41 8 the the DT cord-004775-foaf3vyl 41 9 tubular tubular JJ cord-004775-foaf3vyl 41 10 structure structure NN cord-004775-foaf3vyl 41 11 of of IN cord-004775-foaf3vyl 41 12 the the DT cord-004775-foaf3vyl 41 13 core core NN cord-004775-foaf3vyl 41 14 . . . cord-004775-foaf3vyl 42 1 Thin thin JJ cord-004775-foaf3vyl 42 2 sections section NNS cord-004775-foaf3vyl 42 3 through through IN cord-004775-foaf3vyl 42 4 BRV BRV NNP cord-004775-foaf3vyl 42 5 infected infect VBN cord-004775-foaf3vyl 42 6 intestinal intestinal JJ cord-004775-foaf3vyl 42 7 cells cell NNS cord-004775-foaf3vyl 42 8 of of IN cord-004775-foaf3vyl 42 9 calves calf NNS cord-004775-foaf3vyl 42 10 ( ( -LRB- cord-004775-foaf3vyl 42 11 10 10 CD cord-004775-foaf3vyl 42 12 , , , cord-004775-foaf3vyl 42 13 11 11 CD cord-004775-foaf3vyl 42 14 , , , cord-004775-foaf3vyl 42 15 12 12 CD cord-004775-foaf3vyl 42 16 ) ) -RRB- cord-004775-foaf3vyl 42 17 showed show VBD cord-004775-foaf3vyl 42 18 elongated elongated JJ cord-004775-foaf3vyl 42 19 viral viral JJ cord-004775-foaf3vyl 42 20 particles particle NNS cord-004775-foaf3vyl 42 21 with with IN cord-004775-foaf3vyl 42 22 rounded rounded JJ cord-004775-foaf3vyl 42 23 ends end NNS cord-004775-foaf3vyl 42 24 measuring measure VBG cord-004775-foaf3vyl 42 25 42 42 CD cord-004775-foaf3vyl 42 26 × × NN cord-004775-foaf3vyl 42 27 100.5 100.5 CD cord-004775-foaf3vyl 42 28 nm nm NN cord-004775-foaf3vyl 42 29 . . . cord-004775-foaf3vyl 43 1 In in IN cord-004775-foaf3vyl 43 2 cross cross JJ cord-004775-foaf3vyl 43 3 - - NNS cord-004775-foaf3vyl 43 4 sections section NNS cord-004775-foaf3vyl 43 5 a a DT cord-004775-foaf3vyl 43 6 core core NN cord-004775-foaf3vyl 43 7 of of IN cord-004775-foaf3vyl 43 8 high high JJ cord-004775-foaf3vyl 43 9 electron electron NN cord-004775-foaf3vyl 43 10 density density NN cord-004775-foaf3vyl 43 11 with with IN cord-004775-foaf3vyl 43 12 an an DT cord-004775-foaf3vyl 43 13 electron electron NN cord-004775-foaf3vyl 43 14 lucent lucent NN cord-004775-foaf3vyl 43 15 , , , cord-004775-foaf3vyl 43 16 central central JJ cord-004775-foaf3vyl 43 17 channel channel NN cord-004775-foaf3vyl 43 18 could could MD cord-004775-foaf3vyl 43 19 be be VB cord-004775-foaf3vyl 43 20 discerned discern VBN cord-004775-foaf3vyl 43 21 from from IN cord-004775-foaf3vyl 43 22 a a DT cord-004775-foaf3vyl 43 23 fuzzy fuzzy JJ cord-004775-foaf3vyl 43 24 outer outer JJ cord-004775-foaf3vyl 43 25 membrane membrane NN cord-004775-foaf3vyl 43 26 of of IN cord-004775-foaf3vyl 43 27 medium medium JJ cord-004775-foaf3vyl 43 28 electron electron NN cord-004775-foaf3vyl 43 29 density density NN cord-004775-foaf3vyl 43 30 . . . cord-004775-foaf3vyl 44 1 For for IN cord-004775-foaf3vyl 44 2 both both DT cord-004775-foaf3vyl 44 3 viruses virus NNS cord-004775-foaf3vyl 44 4 the the DT cord-004775-foaf3vyl 44 5 core core NN cord-004775-foaf3vyl 44 6 was be VBD cord-004775-foaf3vyl 44 7 reported report VBN cord-004775-foaf3vyl 44 8 to to TO cord-004775-foaf3vyl 44 9 measure measure VB cord-004775-foaf3vyl 44 10 22 22 CD cord-004775-foaf3vyl 44 11 - - SYM cord-004775-foaf3vyl 44 12 24 24 CD cord-004775-foaf3vyl 44 13 nm nm NN cord-004775-foaf3vyl 44 14 in in IN cord-004775-foaf3vyl 44 15 diameter diameter NN cord-004775-foaf3vyl 44 16 ( ( -LRB- cord-004775-foaf3vyl 44 17 2 2 CD cord-004775-foaf3vyl 44 18 , , , cord-004775-foaf3vyl 44 19 9 9 CD cord-004775-foaf3vyl 44 20 , , , cord-004775-foaf3vyl 44 21 12 12 CD cord-004775-foaf3vyl 44 22 ) ) -RRB- cord-004775-foaf3vyl 44 23 . . . cord-004775-foaf3vyl 45 1 The the DT cord-004775-foaf3vyl 45 2 length length NN cord-004775-foaf3vyl 45 3 of of IN cord-004775-foaf3vyl 45 4 the the DT cord-004775-foaf3vyl 45 5 nueleocapsid nueleocapsid NN cord-004775-foaf3vyl 45 6 can can MD cord-004775-foaf3vyl 45 7 only only RB cord-004775-foaf3vyl 45 8 be be VB cord-004775-foaf3vyl 45 9 approximated approximate VBN cord-004775-foaf3vyl 45 10 ; ; : cord-004775-foaf3vyl 45 11 it -PRON- PRP cord-004775-foaf3vyl 45 12 depends depend VBZ cord-004775-foaf3vyl 45 13 on on IN cord-004775-foaf3vyl 45 14 the the DT cord-004775-foaf3vyl 45 15 orientation orientation NN cord-004775-foaf3vyl 45 16 in in IN cord-004775-foaf3vyl 45 17 space space NN cord-004775-foaf3vyl 45 18 of of IN cord-004775-foaf3vyl 45 19 the the DT cord-004775-foaf3vyl 45 20 virion virion NN cord-004775-foaf3vyl 45 21 and and CC cord-004775-foaf3vyl 45 22 the the DT cord-004775-foaf3vyl 45 23 plane plane NN cord-004775-foaf3vyl 45 24 of of IN cord-004775-foaf3vyl 45 25 section section NN cord-004775-foaf3vyl 45 26 . . . cord-004775-foaf3vyl 46 1 In in IN cord-004775-foaf3vyl 46 2 BEV BEV NNP cord-004775-foaf3vyl 46 3 a a DT cord-004775-foaf3vyl 46 4 mean mean JJ cord-004775-foaf3vyl 46 5 length length NN cord-004775-foaf3vyl 46 6 of of IN cord-004775-foaf3vyl 46 7 104 104 CD cord-004775-foaf3vyl 46 8 nm nm NN cord-004775-foaf3vyl 46 9 ( ( -LRB- cord-004775-foaf3vyl 46 10 _ _ NN cord-004775-foaf3vyl 46 11 + + SYM cord-004775-foaf3vyl 46 12 16 16 CD cord-004775-foaf3vyl 46 13 nm nm NN cord-004775-foaf3vyl 46 14 , , , cord-004775-foaf3vyl 46 15 n n NN cord-004775-foaf3vyl 46 16 = = SYM cord-004775-foaf3vyl 46 17 90 90 CD cord-004775-foaf3vyl 46 18 ) ) -RRB- cord-004775-foaf3vyl 46 19 was be VBD cord-004775-foaf3vyl 46 20 calculated calculate VBN cord-004775-foaf3vyl 46 21 , , , cord-004775-foaf3vyl 46 22 but but CC cord-004775-foaf3vyl 46 23 cores core NNS cord-004775-foaf3vyl 46 24 exceeding exceed VBG cord-004775-foaf3vyl 46 25 200 200 CD cord-004775-foaf3vyl 46 26 nm nm NN cord-004775-foaf3vyl 46 27 in in IN cord-004775-foaf3vyl 46 28 length length NN cord-004775-foaf3vyl 46 29 have have VBP cord-004775-foaf3vyl 46 30 been be VBN cord-004775-foaf3vyl 46 31 encountered encounter VBN cord-004775-foaf3vyl 46 32 ( ( -LRB- cord-004775-foaf3vyl 46 33 2 2 CD cord-004775-foaf3vyl 46 34 , , , cord-004775-foaf3vyl 46 35 9 9 CD cord-004775-foaf3vyl 46 36 ) ) -RRB- cord-004775-foaf3vyl 46 37 . . . cord-004775-foaf3vyl 47 1 It -PRON- PRP cord-004775-foaf3vyl 47 2 was be VBD cord-004775-foaf3vyl 47 3 concluded conclude VBN cord-004775-foaf3vyl 47 4 that that IN cord-004775-foaf3vyl 47 5 , , , cord-004775-foaf3vyl 47 6 toroviruses toroviruse NNS cord-004775-foaf3vyl 47 7 are be VBP cord-004775-foaf3vyl 47 8 enveloped envelop VBN cord-004775-foaf3vyl 47 9 , , , cord-004775-foaf3vyl 47 10 peplomer peplomer NN cord-004775-foaf3vyl 47 11 - - HYPH cord-004775-foaf3vyl 47 12 bearing bear VBG cord-004775-foaf3vyl 47 13 particles particle NNS cord-004775-foaf3vyl 47 14 " " '' cord-004775-foaf3vyl 47 15 containing contain VBG cord-004775-foaf3vyl 47 16 an an DT cord-004775-foaf3vyl 47 17 elongated elongated JJ cord-004775-foaf3vyl 47 18 tubular tubular JJ cord-004775-foaf3vyl 47 19 nueleocapsid nueleocapsid NN cord-004775-foaf3vyl 47 20 of of IN cord-004775-foaf3vyl 47 21 presumably presumably RB cord-004775-foaf3vyl 47 22 helical helical JJ cord-004775-foaf3vyl 47 23 symmetry symmetry NN cord-004775-foaf3vyl 47 24 . . . cord-004775-foaf3vyl 48 1 The the DT cord-004775-foaf3vyl 48 2 eapsid eapsid NN cord-004775-foaf3vyl 48 3 may may MD cord-004775-foaf3vyl 48 4 be be VB cord-004775-foaf3vyl 48 5 bent bend VBN cord-004775-foaf3vyl 48 6 into into IN cord-004775-foaf3vyl 48 7 an an DT cord-004775-foaf3vyl 48 8 open open JJ cord-004775-foaf3vyl 48 9 toms tom NNS cord-004775-foaf3vyl 48 10 , , , cord-004775-foaf3vyl 48 11 conferring confer VBG cord-004775-foaf3vyl 48 12 a a DT cord-004775-foaf3vyl 48 13 disk disk NN cord-004775-foaf3vyl 48 14 - - HYPH cord-004775-foaf3vyl 48 15 or or CC cord-004775-foaf3vyl 48 16 kidney kidney NN cord-004775-foaf3vyl 48 17 - - HYPH cord-004775-foaf3vyl 48 18 shaped shape VBN cord-004775-foaf3vyl 48 19 morphology morphology NN cord-004775-foaf3vyl 48 20 to to IN cord-004775-foaf3vyl 48 21 the the DT cord-004775-foaf3vyl 48 22 virion virion NN cord-004775-foaf3vyl 48 23 ( ( -LRB- cord-004775-foaf3vyl 48 24 largest large JJS cord-004775-foaf3vyl 48 25 diameter diameter NN cord-004775-foaf3vyl 48 26 120 120 CD cord-004775-foaf3vyl 48 27 - - SYM cord-004775-foaf3vyl 48 28 140 140 CD cord-004775-foaf3vyl 48 29 nm nm NN cord-004775-foaf3vyl 48 30 ) ) -RRB- cord-004775-foaf3vyl 48 31 or or CC cord-004775-foaf3vyl 48 32 straight straight RB cord-004775-foaf3vyl 48 33 , , , cord-004775-foaf3vyl 48 34 resulting result VBG cord-004775-foaf3vyl 48 35 in in IN cord-004775-foaf3vyl 48 36 a a DT cord-004775-foaf3vyl 48 37 rod rod NN cord-004775-foaf3vyl 48 38 - - HYPH cord-004775-foaf3vyl 48 39 shaped shape VBN cord-004775-foaf3vyl 48 40 particle particle NN cord-004775-foaf3vyl 48 41 ( ( -LRB- cord-004775-foaf3vyl 48 42 dimensions dimension NNS cord-004775-foaf3vyl 48 43 35 35 CD cord-004775-foaf3vyl 48 44 × × NN cord-004775-foaf3vyl 48 45 170 170 CD cord-004775-foaf3vyl 48 46 nm nm NN cord-004775-foaf3vyl 48 47 ) ) -RRB- cord-004775-foaf3vyl 48 48 " " '' cord-004775-foaf3vyl 48 49 ( ( -LRB- cord-004775-foaf3vyl 48 50 3 3 CD cord-004775-foaf3vyl 48 51 ) ) -RRB- cord-004775-foaf3vyl 48 52 . . . cord-004775-foaf3vyl 49 1 Proteins protein NNS cord-004775-foaf3vyl 49 2 : : : cord-004775-foaf3vyl 50 1 In in IN cord-004775-foaf3vyl 50 2 polyacrylamide polyacrylamide NN cord-004775-foaf3vyl 50 3 gel gel NN cord-004775-foaf3vyl 50 4 electrophoresis electrophoresis NN cord-004775-foaf3vyl 50 5 ( ( -LRB- cord-004775-foaf3vyl 50 6 PAGE page NN cord-004775-foaf3vyl 50 7 ) ) -RRB- cord-004775-foaf3vyl 50 8 BEV BEV NNP cord-004775-foaf3vyl 50 9 and and CC cord-004775-foaf3vyl 50 10 BRV BRV NNP cord-004775-foaf3vyl 50 11 proteins protein NNS cord-004775-foaf3vyl 50 12 showed show VBD cord-004775-foaf3vyl 50 13 quite quite RB cord-004775-foaf3vyl 50 14 similar similar JJ cord-004775-foaf3vyl 50 15 patterns pattern NNS cord-004775-foaf3vyl 50 16 of of IN cord-004775-foaf3vyl 50 17 molecular molecular JJ cord-004775-foaf3vyl 50 18 weights weight NNS cord-004775-foaf3vyl 50 19 ( ( -LRB- cord-004775-foaf3vyl 50 20 mol mol NNP cord-004775-foaf3vyl 50 21 . . . cord-004775-foaf3vyl 50 22 wts wts NNP cord-004775-foaf3vyl 50 23 ) ) -RRB- cord-004775-foaf3vyl 50 24 . . . cord-004775-foaf3vyl 51 1 Metabolically metabolically RB cord-004775-foaf3vyl 51 2 labelled label VBN cord-004775-foaf3vyl 51 3 BEV BEV NNP cord-004775-foaf3vyl 51 4 preparations preparation NNS cord-004775-foaf3vyl 51 5 revealed reveal VBD cord-004775-foaf3vyl 51 6 structural structural JJ cord-004775-foaf3vyl 51 7 proteins protein NNS cord-004775-foaf3vyl 51 8 in in IN cord-004775-foaf3vyl 51 9 the the DT cord-004775-foaf3vyl 51 10 range range NN cord-004775-foaf3vyl 51 11 of of IN cord-004775-foaf3vyl 51 12 75 75 CD cord-004775-foaf3vyl 51 13 - - SYM cord-004775-foaf3vyl 51 14 100 100 CD cord-004775-foaf3vyl 51 15 , , , cord-004775-foaf3vyl 51 16 37 37 CD cord-004775-foaf3vyl 51 17 , , , cord-004775-foaf3vyl 51 18 22 22 CD cord-004775-foaf3vyl 51 19 , , , cord-004775-foaf3vyl 51 20 and and CC cord-004775-foaf3vyl 51 21 20 20 CD cord-004775-foaf3vyl 51 22 kD kd XX cord-004775-foaf3vyl 51 23 ( ( -LRB- cord-004775-foaf3vyl 51 24 13 13 CD cord-004775-foaf3vyl 51 25 , , , cord-004775-foaf3vyl 51 26 14 14 CD cord-004775-foaf3vyl 51 27 ) ) -RRB- cord-004775-foaf3vyl 51 28 . . . cord-004775-foaf3vyl 52 1 In in IN cord-004775-foaf3vyl 52 2 radioiodinated radioiodinated JJ cord-004775-foaf3vyl 52 3 purified purify VBN cord-004775-foaf3vyl 52 4 intact intact JJ cord-004775-foaf3vyl 52 5 BEV BEV NNP cord-004775-foaf3vyl 52 6 the the DT cord-004775-foaf3vyl 52 7 22 22 CD cord-004775-foaf3vyl 52 8 and and CC cord-004775-foaf3vyl 52 9 37 37 CD cord-004775-foaf3vyl 52 10 kD kd JJ cord-004775-foaf3vyl 52 11 proteins protein NNS cord-004775-foaf3vyl 52 12 were be VBD cord-004775-foaf3vyl 52 13 labelled label VBN cord-004775-foaf3vyl 52 14 ; ; : cord-004775-foaf3vyl 52 15 when when WRB cord-004775-foaf3vyl 52 16 the the DT cord-004775-foaf3vyl 52 17 preparation preparation NN cord-004775-foaf3vyl 52 18 was be VBD cord-004775-foaf3vyl 52 19 treated treat VBN cord-004775-foaf3vyl 52 20 with with IN cord-004775-foaf3vyl 52 21 Triton Triton NNP cord-004775-foaf3vyl 52 22 X-100 x-100 NN cord-004775-foaf3vyl 52 23 , , , cord-004775-foaf3vyl 52 24 the the DT cord-004775-foaf3vyl 52 25 20 20 CD cord-004775-foaf3vyl 52 26 kD kD NNP cord-004775-foaf3vyl 52 27 polypeptide polypeptide NN cord-004775-foaf3vyl 52 28 was be VBD cord-004775-foaf3vyl 52 29 labelled label VBN cord-004775-foaf3vyl 52 30 in in IN cord-004775-foaf3vyl 52 31 addition addition NN cord-004775-foaf3vyl 52 32 ( ( -LRB- cord-004775-foaf3vyl 52 33 Fig Fig NNP cord-004775-foaf3vyl 52 34 . . . cord-004775-foaf3vyl 52 35 3 3 CD cord-004775-foaf3vyl 52 36 ) ) -RRB- cord-004775-foaf3vyl 52 37 . . . cord-004775-foaf3vyl 53 1 Radioiodinated radioiodinated JJ cord-004775-foaf3vyl 53 2 BRV BRV NNP cord-004775-foaf3vyl 53 3 polypeptides polypeptide NNS cord-004775-foaf3vyl 53 4 were be VBD cord-004775-foaf3vyl 53 5 encountered encounter VBN cord-004775-foaf3vyl 53 6 with with IN cord-004775-foaf3vyl 53 7 apparent apparent JJ cord-004775-foaf3vyl 53 8 mol mol NN cord-004775-foaf3vyl 53 9 . . . cord-004775-foaf3vyl 54 1 wts wts NNP cord-004775-foaf3vyl 54 2 of of IN cord-004775-foaf3vyl 54 3 105 105 CD cord-004775-foaf3vyl 54 4 , , , cord-004775-foaf3vyl 54 5 85 85 CD cord-004775-foaf3vyl 54 6 , , , cord-004775-foaf3vyl 54 7 37 37 CD cord-004775-foaf3vyl 54 8 k k NN cord-004775-foaf3vyl 54 9 and and CC cord-004775-foaf3vyl 55 1 and and CC cord-004775-foaf3vyl 55 2 in in IN cord-004775-foaf3vyl 55 3 the the DT cord-004775-foaf3vyl 55 4 20 20 CD cord-004775-foaf3vyl 55 5 k k NN cord-004775-foaf3vyl 55 6 range range NN cord-004775-foaf3vyl 55 7 ( ( -LRB- cord-004775-foaf3vyl 55 8 15 15 CD cord-004775-foaf3vyl 55 9 ) ) -RRB- cord-004775-foaf3vyl 55 10 . . . cord-004775-foaf3vyl 56 1 The the DT cord-004775-foaf3vyl 56 2 20 20 CD cord-004775-foaf3vyl 56 3 and and CC cord-004775-foaf3vyl 56 4 37 37 CD cord-004775-foaf3vyl 56 5 kD kd JJ cord-004775-foaf3vyl 56 6 proteins protein NNS cord-004775-foaf3vyl 56 7 of of IN cord-004775-foaf3vyl 56 8 BEV BEV NNP cord-004775-foaf3vyl 56 9 are be VBP cord-004775-foaf3vyl 56 10 both both DT cord-004775-foaf3vyl 56 11 phosphorylated phosphorylated JJ cord-004775-foaf3vyl 56 12 . . . cord-004775-foaf3vyl 57 1 The the DT cord-004775-foaf3vyl 57 2 20 20 CD cord-004775-foaf3vyl 57 3 kD kD NNP cord-004775-foaf3vyl 57 4 protein protein NN cord-004775-foaf3vyl 57 5 is be VBZ cord-004775-foaf3vyl 57 6 the the DT cord-004775-foaf3vyl 57 7 : : : cord-004775-foaf3vyl 57 8 most most RBS cord-004775-foaf3vyl 57 9 prevalent prevalent JJ cord-004775-foaf3vyl 57 10 protein protein NN cord-004775-foaf3vyl 57 11 in in IN cord-004775-foaf3vyl 57 12 BEV BEV NNP cord-004775-foaf3vyl 57 13 , , , cord-004775-foaf3vyl 57 14 accounting accounting NN cord-004775-foaf3vyl 57 15 tbr tbr NNP cord-004775-foaf3vyl 57 16 about about RB cord-004775-foaf3vyl 57 17 84 84 CD cord-004775-foaf3vyl 57 18 per per NN cord-004775-foaf3vyl 57 19 cent cent NN cord-004775-foaf3vyl 57 20 of of IN cord-004775-foaf3vyl 57 21 the the DT cord-004775-foaf3vyl 57 22 total total JJ cord-004775-foaf3vyl 57 23 protein protein NN cord-004775-foaf3vyl 57 24 mass mass NN cord-004775-foaf3vyl 57 25 . . . cord-004775-foaf3vyl 58 1 It -PRON- PRP cord-004775-foaf3vyl 58 2 has have VBZ cord-004775-foaf3vyl 58 3 I -PRON- PRP cord-004775-foaf3vyl 58 4 ~ ~ CD cord-004775-foaf3vyl 58 5 NA NA NNP cord-004775-foaf3vyl 58 6 binding bind VBG cord-004775-foaf3vyl 58 7 properties property NNS cord-004775-foaf3vyl 58 8 and and CC cord-004775-foaf3vyl 58 9 was be VBD cord-004775-foaf3vyl 58 10 found find VBN cord-004775-foaf3vyl 58 11 in in IN cord-004775-foaf3vyl 58 12 an an DT cord-004775-foaf3vyl 58 13 intraeellular intraeellular JJ cord-004775-foaf3vyl 58 14 substructure substructure NN cord-004775-foaf3vyl 58 15 of of IN cord-004775-foaf3vyl 58 16 higher high JJR cord-004775-foaf3vyl 58 17 density density NN cord-004775-foaf3vyl 58 18 than than IN cord-004775-foaf3vyl 58 19 tlhe tlhe NNP cord-004775-foaf3vyl 58 20 virion virion NNP cord-004775-foaf3vyl 58 21 ( ( -LRB- cord-004775-foaf3vyl 58 22 d d NN cord-004775-foaf3vyl 58 23 = = SYM cord-004775-foaf3vyl 58 24 1.36 1.36 CD cord-004775-foaf3vyl 58 25 g/ g/ NNPS cord-004775-foaf3vyl 58 26 ml ml NNP cord-004775-foaf3vyl 58 27 in in IN cord-004775-foaf3vyl 58 28 CsC1 CsC1 NNP cord-004775-foaf3vyl 58 29 ) ) -RRB- cord-004775-foaf3vyl 58 30 . . . cord-004775-foaf3vyl 59 1 It -PRON- PRP cord-004775-foaf3vyl 59 2 is be VBZ cord-004775-foaf3vyl 59 3 therefore therefore RB cord-004775-foaf3vyl 59 4 suggested suggest VBN cord-004775-foaf3vyl 59 5 to to TO cord-004775-foaf3vyl 59 6 represent represent VB cord-004775-foaf3vyl 59 7 the the DT cord-004775-foaf3vyl 59 8 main main JJ cord-004775-foaf3vyl 59 9 capsid capsid NN cord-004775-foaf3vyl 59 10 protein protein NN cord-004775-foaf3vyl 59 11 ( ( -LRB- cord-004775-foaf3vyl 59 12 14 14 CD cord-004775-foaf3vyl 59 13 ) ) -RRB- cord-004775-foaf3vyl 59 14 . . . cord-004775-foaf3vyl 60 1 In in IN cord-004775-foaf3vyl 60 2 radioimmune radioimmune JJ cord-004775-foaf3vyl 60 3 precipitation precipitation NN cord-004775-foaf3vyl 60 4 ( ( -LRB- cord-004775-foaf3vyl 60 5 RIP rip NN cord-004775-foaf3vyl 60 6 ) ) -RRB- cord-004775-foaf3vyl 60 7 it -PRON- PRP cord-004775-foaf3vyl 60 8 , , , cord-004775-foaf3vyl 60 9 was be VBD cord-004775-foaf3vyl 60 10 recognized recognize VBN cord-004775-foaf3vyl 60 11 preferentially preferentially RB cord-004775-foaf3vyl 60 12 by by IN cord-004775-foaf3vyl 60 13 heterologous heterologous NNP cord-004775-foaf3vyl 60 14 sera sera NNP cord-004775-foaf3vyl 60 15 ( ( -LRB- cord-004775-foaf3vyl 60 16 cattle cattle NNS cord-004775-foaf3vyl 60 17 ) ) -RRB- cord-004775-foaf3vyl 60 18 , , , cord-004775-foaf3vyl 60 19 another another DT cord-004775-foaf3vyl 60 20 indication indication NN cord-004775-foaf3vyl 60 21 that that IN cord-004775-foaf3vyl 60 22 the the DT cord-004775-foaf3vyl 60 23 20kD 20kd CD cord-004775-foaf3vyl 60 24 protein protein NN cord-004775-foaf3vyl 60 25 corresponds correspond VBZ cord-004775-foaf3vyl 60 26 to to IN cord-004775-foaf3vyl 60 27 an an DT cord-004775-foaf3vyl 60 28 internal internal JJ cord-004775-foaf3vyl 60 29 , , , cord-004775-foaf3vyl 60 30 evolutionary evolutionary JJ cord-004775-foaf3vyl 60 31 conserved conserve VBN cord-004775-foaf3vyl 60 32 , , , cord-004775-foaf3vyl 60 33 and and CC cord-004775-foaf3vyl 60 34 broadly broadly RB cord-004775-foaf3vyl 60 35 crossreactive crossreactive JJ cord-004775-foaf3vyl 60 36 protein protein NN cord-004775-foaf3vyl 60 37 . . . cord-004775-foaf3vyl 61 1 Second second JJ cord-004775-foaf3vyl 61 2 in in IN cord-004775-foaf3vyl 61 3 abundance abundance NN cord-004775-foaf3vyl 61 4 ( ( -LRB- cord-004775-foaf3vyl 61 5 about about RB cord-004775-foaf3vyl 61 6 13 13 CD cord-004775-foaf3vyl 61 7 per per IN cord-004775-foaf3vyl 61 8 cent cent NN cord-004775-foaf3vyl 61 9 of of IN cord-004775-foaf3vyl 61 10 the the DT cord-004775-foaf3vyl 61 11 virion virion NN cord-004775-foaf3vyl 61 12 protein protein NN cord-004775-foaf3vyl 61 13 mass mass NNP cord-004775-foaf3vyl 61 14 ) ) -RRB- cord-004775-foaf3vyl 61 15 is be VBZ cord-004775-foaf3vyl 61 16 the the DT cord-004775-foaf3vyl 61 17 22 22 CD cord-004775-foaf3vyl 61 18 kD kD NNP cord-004775-foaf3vyl 61 19 protein protein NN cord-004775-foaf3vyl 61 20 . . . cord-004775-foaf3vyl 62 1 It -PRON- PRP cord-004775-foaf3vyl 62 2 is be VBZ cord-004775-foaf3vyl 62 3 neither neither CC cord-004775-foaf3vyl 62 4 phosphorylated phosphorylated JJ cord-004775-foaf3vyl 62 5 nor nor CC cord-004775-foaf3vyl 62 6 glycosylated glycosylated JJ cord-004775-foaf3vyl 62 7 . . . cord-004775-foaf3vyl 63 1 After after IN cord-004775-foaf3vyl 63 2 treatment treatment NN cord-004775-foaf3vyl 63 3 , , , cord-004775-foaf3vyl 63 4 of of IN cord-004775-foaf3vyl 63 5 virions virion NNS cord-004775-foaf3vyl 63 6 with with IN cord-004775-foaf3vyl 63 7 Triton Triton NNP cord-004775-foaf3vyl 63 8 X-100 x-100 IN cord-004775-foaf3vyl 63 9 the the DT cord-004775-foaf3vyl 63 10 22 22 CD cord-004775-foaf3vyl 63 11 kD kD NNP cord-004775-foaf3vyl 63 12 polypeptide polypeptide NN cord-004775-foaf3vyl 63 13 was be VBD cord-004775-foaf3vyl 63 14 found find VBN cord-004775-foaf3vyl 63 15 in in IN cord-004775-foaf3vyl 63 16 slowly slowly RB cord-004775-foaf3vyl 63 17 sedimenting sediment VBG cord-004775-foaf3vyl 63 18 material material NN cord-004775-foaf3vyl 63 19 , , , cord-004775-foaf3vyl 63 20 an an DT cord-004775-foaf3vyl 63 21 observation observation NN cord-004775-foaf3vyl 63 22 indicative indicative JJ cord-004775-foaf3vyl 63 23 of of IN cord-004775-foaf3vyl 63 24 its -PRON- PRP$ cord-004775-foaf3vyl 63 25 membrane membrane NNP cord-004775-foaf3vyl 63 26 association association NNP cord-004775-foaf3vyl 63 27 . . . cord-004775-foaf3vyl 64 1 The the DT cord-004775-foaf3vyl 64 2 22 22 CD cord-004775-foaf3vyl 64 3 kD kD NNP cord-004775-foaf3vyl 64 4 protein protein NN cord-004775-foaf3vyl 64 5 is be VBZ cord-004775-foaf3vyl 64 6 therefore therefore RB cord-004775-foaf3vyl 64 7 a a DT cord-004775-foaf3vyl 64 8 likely likely JJ cord-004775-foaf3vyl 64 9 candidate candidate NN cord-004775-foaf3vyl 64 10 for for IN cord-004775-foaf3vyl 64 11 an an DT cord-004775-foaf3vyl 64 12 envelope envelope NN cord-004775-foaf3vyl 64 13 protein protein NN cord-004775-foaf3vyl 64 14 ( ( -LRB- cord-004775-foaf3vyl 64 15 14 14 CD cord-004775-foaf3vyl 64 16 ) ) -RRB- cord-004775-foaf3vyl 64 17 , , . cord-004775-foaf3vyl 65 1 ( ( -LRB- cord-004775-foaf3vyl 65 2 HORZINEK HORZINEK NNP cord-004775-foaf3vyl 65 3 et et NNP cord-004775-foaf3vyl 65 4 al al NNP cord-004775-foaf3vyl 65 5 . . NNP cord-004775-foaf3vyl 65 6 , , , cord-004775-foaf3vyl 65 7 unpublished unpublished JJ cord-004775-foaf3vyl 65 8 results result NNS cord-004775-foaf3vyl 65 9 ) ) -RRB- cord-004775-foaf3vyl 65 10 . . . cord-004775-foaf3vyl 66 1 The the DT cord-004775-foaf3vyl 66 2 low low JJ cord-004775-foaf3vyl 66 3 molecular molecular JJ cord-004775-foaf3vyl 66 4 weight weight NN cord-004775-foaf3vyl 66 5 polypeptide polypeptide NN cord-004775-foaf3vyl 66 6 of of IN cord-004775-foaf3vyl 66 7 B b NN cord-004775-foaf3vyl 66 8 R r NN cord-004775-foaf3vyl 66 9 V v NN cord-004775-foaf3vyl 66 10 does do VBZ cord-004775-foaf3vyl 66 11 not not RB cord-004775-foaf3vyl 66 12 comigrate comigrate VB cord-004775-foaf3vyl 66 13 in in IN cord-004775-foaf3vyl 66 14 PAGE page NN cord-004775-foaf3vyl 66 15 with with IN cord-004775-foaf3vyl 66 16 the the DT cord-004775-foaf3vyl 66 17 20 20 CD cord-004775-foaf3vyl 66 18 kD kD NNP cord-004775-foaf3vyl 66 19 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 66 20 protein protein NN cord-004775-foaf3vyl 66 21 of of IN cord-004775-foaf3vyl 66 22 BEV BEV NNP cord-004775-foaf3vyl 66 23 and and CC cord-004775-foaf3vyl 66 24 seems seem VBZ cord-004775-foaf3vyl 66 25 to to TO cord-004775-foaf3vyl 66 26 be be VB cord-004775-foaf3vyl 66 27 larger large JJR cord-004775-foaf3vyl 66 28 . . . cord-004775-foaf3vyl 67 1 Its -PRON- PRP$ cord-004775-foaf3vyl 67 2 migration migration NN cord-004775-foaf3vyl 67 3 behaviour behaviour NN cord-004775-foaf3vyl 67 4 was be VBD cord-004775-foaf3vyl 67 5 affected affect VBN cord-004775-foaf3vyl 67 6 by by IN cord-004775-foaf3vyl 67 7 ether ether NN cord-004775-foaf3vyl 67 8 extraction extraction NN cord-004775-foaf3vyl 67 9 suggesting suggest VBG cord-004775-foaf3vyl 67 10 a a DT cord-004775-foaf3vyl 67 11 membrane membrane NN cord-004775-foaf3vyl 67 12 association association NN cord-004775-foaf3vyl 67 13 and and CC cord-004775-foaf3vyl 67 14 a a DT cord-004775-foaf3vyl 67 15 correspondance correspondance NN cord-004775-foaf3vyl 67 16 to to IN cord-004775-foaf3vyl 67 17 the the DT cord-004775-foaf3vyl 67 18 22 22 CD cord-004775-foaf3vyl 67 19 kD kD NNP cord-004775-foaf3vyl 67 20 protein protein NN cord-004775-foaf3vyl 67 21 of of IN cord-004775-foaf3vyl 67 22 BEV BEV NNP cord-004775-foaf3vyl 67 23 ( ( -LRB- cord-004775-foaf3vyl 67 24 15 15 CD cord-004775-foaf3vyl 67 25 ) ) -RRB- cord-004775-foaf3vyl 67 26 . . . cord-004775-foaf3vyl 68 1 No no DT cord-004775-foaf3vyl 68 2 function function NN cord-004775-foaf3vyl 68 3 could could MD cord-004775-foaf3vyl 68 4 be be VB cord-004775-foaf3vyl 68 5 attributed attribute VBN cord-004775-foaf3vyl 68 6 to to IN cord-004775-foaf3vyl 68 7 the the DT cord-004775-foaf3vyl 68 8 phosphorylated phosphorylated JJ cord-004775-foaf3vyl 68 9 37 37 CD cord-004775-foaf3vyl 68 10 kD kD NNP cord-004775-foaf3vyl 68 11 protein protein NN cord-004775-foaf3vyl 68 12 so so RB cord-004775-foaf3vyl 68 13 far far RB cord-004775-foaf3vyl 68 14 ; ; : cord-004775-foaf3vyl 68 15 it -PRON- PRP cord-004775-foaf3vyl 68 16 is be VBZ cord-004775-foaf3vyl 68 17 assumed assume VBN cord-004775-foaf3vyl 68 18 to to TO cord-004775-foaf3vyl 68 19 serve serve VB cord-004775-foaf3vyl 68 20 as as IN cord-004775-foaf3vyl 68 21 a a DT cord-004775-foaf3vyl 68 22 matrix matrix NN cord-004775-foaf3vyl 68 23 protein protein NN cord-004775-foaf3vyl 68 24 . . . cord-004775-foaf3vyl 69 1 The the DT cord-004775-foaf3vyl 69 2 high high JJ cord-004775-foaf3vyl 69 3 molecular molecular JJ cord-004775-foaf3vyl 69 4 weight weight NN cord-004775-foaf3vyl 69 5 virion virion NN cord-004775-foaf3vyl 69 6 protein protein NN cord-004775-foaf3vyl 69 7 in in IN cord-004775-foaf3vyl 69 8 the the DT cord-004775-foaf3vyl 69 9 range range NN cord-004775-foaf3vyl 69 10 of of IN cord-004775-foaf3vyl 69 11 75 75 CD cord-004775-foaf3vyl 69 12 - - SYM cord-004775-foaf3vyl 69 13 100 100 CD cord-004775-foaf3vyl 69 14 kD kD NNS cord-004775-foaf3vyl 69 15 of of IN cord-004775-foaf3vyl 69 16 BEV BEV NNP cord-004775-foaf3vyl 69 17 is be VBZ cord-004775-foaf3vyl 69 18 glycosylated glycosylate VBN cord-004775-foaf3vyl 69 19 , , , cord-004775-foaf3vyl 69 20 probably probably RB cord-004775-foaf3vyl 69 21 by by IN cord-004775-foaf3vyl 69 22 N n NN cord-004775-foaf3vyl 69 23 - - HYPH cord-004775-foaf3vyl 69 24 linked link VBN cord-004775-foaf3vyl 69 25 oligosaccharides oligosaccharide NNS cord-004775-foaf3vyl 69 26 since since IN cord-004775-foaf3vyl 69 27 tunicamycin tunicamycin NNS cord-004775-foaf3vyl 69 28 , , , cord-004775-foaf3vyl 69 29 an an DT cord-004775-foaf3vyl 69 30 antibiotic antibiotic NN cord-004775-foaf3vyl 69 31 known know VBN cord-004775-foaf3vyl 69 32 to to TO cord-004775-foaf3vyl 69 33 inhibit inhibit VB cord-004775-foaf3vyl 69 34 N n CD cord-004775-foaf3vyl 69 35 - - HYPH cord-004775-foaf3vyl 69 36 linked link VBN cord-004775-foaf3vyl 69 37 oligosaccharide oligosaccharide NN cord-004775-foaf3vyl 69 38 synthesis synthesis NN cord-004775-foaf3vyl 69 39 , , , cord-004775-foaf3vyl 69 40 prevented prevent VBD cord-004775-foaf3vyl 69 41 the the DT cord-004775-foaf3vyl 69 42 formation formation NN cord-004775-foaf3vyl 69 43 of of IN cord-004775-foaf3vyl 69 44 infectious infectious JJ cord-004775-foaf3vyl 69 45 virus virus NN cord-004775-foaf3vyl 69 46 as as RB cord-004775-foaf3vyl 69 47 well well RB cord-004775-foaf3vyl 69 48 as as IN cord-004775-foaf3vyl 69 49 appearance appearance NN cord-004775-foaf3vyl 69 50 of of IN cord-004775-foaf3vyl 69 51 the the DT cord-004775-foaf3vyl 69 52 75 75 CD cord-004775-foaf3vyl 69 53 - - SYM cord-004775-foaf3vyl 69 54 100 100 CD cord-004775-foaf3vyl 69 55 kD kd JJ cord-004775-foaf3vyl 69 56 band band NN cord-004775-foaf3vyl 69 57 in in IN cord-004775-foaf3vyl 69 58 PAGE page NN cord-004775-foaf3vyl 69 59 of of IN cord-004775-foaf3vyl 69 60 infected infected JJ cord-004775-foaf3vyl 69 61 cells cell NNS cord-004775-foaf3vyl 69 62 ( ( -LRB- cord-004775-foaf3vyl 69 63 20 20 CD cord-004775-foaf3vyl 69 64 ) ) -RRB- cord-004775-foaf3vyl 69 65 . . . cord-004775-foaf3vyl 70 1 In in IN cord-004775-foaf3vyl 70 2 RIP RIP NNP cord-004775-foaf3vyl 70 3 the the DT cord-004775-foaf3vyl 70 4 75 75 CD cord-004775-foaf3vyl 70 5 - - SYM cord-004775-foaf3vyl 70 6 100 100 CD cord-004775-foaf3vyl 70 7 kD kD NNP cord-004775-foaf3vyl 70 8 protein protein NN cord-004775-foaf3vyl 70 9 of of IN cord-004775-foaf3vyl 70 10 BEV BEV NNP cord-004775-foaf3vyl 70 11 was be VBD cord-004775-foaf3vyl 70 12 preferably preferably RB cord-004775-foaf3vyl 70 13 recognized recognize VBN cord-004775-foaf3vyl 70 14 by by IN cord-004775-foaf3vyl 70 15 a a DT cord-004775-foaf3vyl 70 16 horse horse NN cord-004775-foaf3vyl 70 17 antiserum antiserum NN cord-004775-foaf3vyl 70 18 with with IN cord-004775-foaf3vyl 70 19 high high JJ cord-004775-foaf3vyl 70 20 neutralization neutralization NN cord-004775-foaf3vyl 70 21 activity activity NN cord-004775-foaf3vyl 70 22 ( ( -LRB- cord-004775-foaf3vyl 70 23 14 14 CD cord-004775-foaf3vyl 70 24 ) ) -RRB- cord-004775-foaf3vyl 70 25 . . . cord-004775-foaf3vyl 71 1 Radioiodinated radioiodinated JJ cord-004775-foaf3vyl 71 2 B B NNP cord-004775-foaf3vyl 71 3 R r NN cord-004775-foaf3vyl 71 4 V v NN cord-004775-foaf3vyl 71 5 preparations preparation NNS cord-004775-foaf3vyl 71 6 contained contain VBD cord-004775-foaf3vyl 71 7 genome genome NN cord-004775-foaf3vyl 71 8 : : : cord-004775-foaf3vyl 71 9 BEV BEV NNP cord-004775-foaf3vyl 71 10 replication replication NN cord-004775-foaf3vyl 71 11 is be VBZ cord-004775-foaf3vyl 71 12 not not RB cord-004775-foaf3vyl 71 13 inhibited inhibit VBN cord-004775-foaf3vyl 71 14 by by IN cord-004775-foaf3vyl 71 15 DNA DNA NNP cord-004775-foaf3vyl 71 16 nueleotide nueleotide NN cord-004775-foaf3vyl 71 17 analogous analogous JJ cord-004775-foaf3vyl 71 18 which which WDT cord-004775-foaf3vyl 71 19 indicates indicate VBZ cord-004775-foaf3vyl 71 20 the the DT cord-004775-foaf3vyl 71 21 presence presence NN cord-004775-foaf3vyl 71 22 of of IN cord-004775-foaf3vyl 71 23 an an DT cord-004775-foaf3vyl 71 24 RNA RNA NNP cord-004775-foaf3vyl 71 25 genome genome NN cord-004775-foaf3vyl 71 26 ( ( -LRB- cord-004775-foaf3vyl 71 27 2 2 CD cord-004775-foaf3vyl 71 28 ) ) -RRB- cord-004775-foaf3vyl 71 29 . . . cord-004775-foaf3vyl 72 1 One one CD cord-004775-foaf3vyl 72 2 type type NN cord-004775-foaf3vyl 72 3 of of IN cord-004775-foaf3vyl 72 4 single single JJ cord-004775-foaf3vyl 72 5 stranded strand VBN cord-004775-foaf3vyl 72 6 RNA RNA NNP cord-004775-foaf3vyl 72 7 molecule molecule NN cord-004775-foaf3vyl 72 8 with with IN cord-004775-foaf3vyl 72 9 a a DT cord-004775-foaf3vyl 72 10 mol mol NN cord-004775-foaf3vyl 72 11 . . . cord-004775-foaf3vyl 73 1 wt wt NN cord-004775-foaf3vyl 73 2 of of IN cord-004775-foaf3vyl 73 3 about about RB cord-004775-foaf3vyl 73 4 5.7 5.7 CD cord-004775-foaf3vyl 73 5 × × NN cord-004775-foaf3vyl 73 6 106 106 CD cord-004775-foaf3vyl 73 7 was be VBD cord-004775-foaf3vyl 73 8 isolated isolate VBN cord-004775-foaf3vyl 73 9 from from IN cord-004775-foaf3vyl 73 10 virus virus NN cord-004775-foaf3vyl 73 11 particles particle NNS cord-004775-foaf3vyl 73 12 . . . cord-004775-foaf3vyl 74 1 The the DT cord-004775-foaf3vyl 74 2 virion virion NN cord-004775-foaf3vyl 74 3 RNA RNA NNP cord-004775-foaf3vyl 74 4 was be VBD cord-004775-foaf3vyl 74 5 shown show VBN cord-004775-foaf3vyl 74 6 to to TO cord-004775-foaf3vyl 74 7 be be VB cord-004775-foaf3vyl 74 8 infectious infectious JJ cord-004775-foaf3vyl 74 9 and and CC cord-004775-foaf3vyl 74 10 a a DT cord-004775-foaf3vyl 74 11 positive positive JJ cord-004775-foaf3vyl 74 12 polarity polarity NN cord-004775-foaf3vyl 74 13 is be VBZ cord-004775-foaf3vyl 74 14 suggested suggest VBN cord-004775-foaf3vyl 74 15 . . . cord-004775-foaf3vyl 75 1 Polyadenylation Polyadenylation NNP cord-004775-foaf3vyl 75 2 of of IN cord-004775-foaf3vyl 75 3 genomie genomie NNP cord-004775-foaf3vyl 75 4 RNA RNA NNP cord-004775-foaf3vyl 75 5 was be VBD cord-004775-foaf3vyl 75 6 apparent apparent JJ cord-004775-foaf3vyl 75 7 from from IN cord-004775-foaf3vyl 75 8 oligo oligo NNP cord-004775-foaf3vyl 75 9 dT dT NNP cord-004775-foaf3vyl 75 10 affinity affinity NN cord-004775-foaf3vyl 75 11 chromatography chromatography NN cord-004775-foaf3vyl 75 12 and and CC cord-004775-foaf3vyl 75 13 TI TI NNP cord-004775-foaf3vyl 75 14 l l NN cord-004775-foaf3vyl 75 15 ~ ~ NFP cord-004775-foaf3vyl 75 16 NAse NAse NNP cord-004775-foaf3vyl 75 17 fingerprints fingerprint NNS cord-004775-foaf3vyl 75 18 . . . cord-004775-foaf3vyl 76 1 ( ( -LRB- cord-004775-foaf3vyl 76 2 HoRZlNEt~ HoRZlNEt~ NNP cord-004775-foaf3vyl 76 3 et et NNP cord-004775-foaf3vyl 76 4 al al NNP cord-004775-foaf3vyl 76 5 . . NNP cord-004775-foaf3vyl 76 6 , , , cord-004775-foaf3vyl 76 7 unpublished unpublished JJ cord-004775-foaf3vyl 76 8 results result NNS cord-004775-foaf3vyl 76 9 ) ) -RRB- cord-004775-foaf3vyl 76 10 . . . cord-004775-foaf3vyl 77 1 In in IN cord-004775-foaf3vyl 77 2 a a DT cord-004775-foaf3vyl 77 3 linear linear JJ cord-004775-foaf3vyl 77 4 sucrose sucrose NN cord-004775-foaf3vyl 77 5 gradient gradient NN cord-004775-foaf3vyl 77 6 a a DT cord-004775-foaf3vyl 77 7 virion virion NN cord-004775-foaf3vyl 77 8 buoyant buoyant JJ cord-004775-foaf3vyl 77 9 density density NN cord-004775-foaf3vyl 77 10 of of IN cord-004775-foaf3vyl 77 11 1.16 1.16 CD cord-004775-foaf3vyl 77 12 to to TO cord-004775-foaf3vyl 77 13 1.18 1.18 CD cord-004775-foaf3vyl 77 14 g g NN cord-004775-foaf3vyl 77 15 / / SYM cord-004775-foaf3vyl 77 16 ml ml NN cord-004775-foaf3vyl 77 17 was be VBD cord-004775-foaf3vyl 77 18 determined determine VBN cord-004775-foaf3vyl 77 19 for for IN cord-004775-foaf3vyl 77 20 BEV BEV NNP cord-004775-foaf3vyl 77 21 ( ( -LRB- cord-004775-foaf3vyl 77 22 2 2 CD cord-004775-foaf3vyl 77 23 ) ) -RRB- cord-004775-foaf3vyl 77 24 . . . cord-004775-foaf3vyl 78 1 Under under IN cord-004775-foaf3vyl 78 2 the the DT cord-004775-foaf3vyl 78 3 same same JJ cord-004775-foaf3vyl 78 4 conditions condition NNS cord-004775-foaf3vyl 78 5 BRV BRV NNP cord-004775-foaf3vyl 78 6 2 2 CD cord-004775-foaf3vyl 78 7 banded band VBD cord-004775-foaf3vyl 78 8 at at IN cord-004775-foaf3vyl 78 9 1.18 1.18 CD cord-004775-foaf3vyl 78 10 g g NN cord-004775-foaf3vyl 78 11 / / SYM cord-004775-foaf3vyl 78 12 ml ml NN cord-004775-foaf3vyl 78 13 . . . cord-004775-foaf3vyl 79 1 For for IN cord-004775-foaf3vyl 79 2 BEV BEV NNP cord-004775-foaf3vyl 79 3 and and CC cord-004775-foaf3vyl 79 4 Bt Bt NNP cord-004775-foaf3vyl 79 5 ~ ~ NFP cord-004775-foaf3vyl 79 6 V v NN cord-004775-foaf3vyl 79 7 2 2 CD cord-004775-foaf3vyl 79 8 sedimentation sedimentation NN cord-004775-foaf3vyl 79 9 coefficients coefficient NNS cord-004775-foaf3vyl 79 10 of of IN cord-004775-foaf3vyl 79 11 400 400 CD cord-004775-foaf3vyl 79 12 and and CC cord-004775-foaf3vyl 79 13 350 350 CD cord-004775-foaf3vyl 79 14 S S NNS cord-004775-foaf3vyl 79 15 , , , cord-004775-foaf3vyl 79 16 respectively respectively RB cord-004775-foaf3vyl 79 17 , , , cord-004775-foaf3vyl 79 18 were be VBD cord-004775-foaf3vyl 79 19 estimated estimate VBN cord-004775-foaf3vyl 79 20 ( ( -LRB- cord-004775-foaf3vyl 79 21 15 15 CD cord-004775-foaf3vyl 79 22 ) ) -RRB- cord-004775-foaf3vyl 79 23 . . . cord-004775-foaf3vyl 80 1 In in IN cord-004775-foaf3vyl 80 2 addition addition NN cord-004775-foaf3vyl 80 3 to to IN cord-004775-foaf3vyl 80 4 the the DT cord-004775-foaf3vyl 80 5 main main JJ cord-004775-foaf3vyl 80 6 infectivity infectivity NN cord-004775-foaf3vyl 80 7 ( ( -LRB- cord-004775-foaf3vyl 80 8 400 400 CD cord-004775-foaf3vyl 80 9 S s NN cord-004775-foaf3vyl 80 10 ) ) -RRB- cord-004775-foaf3vyl 80 11 peak peak VB cord-004775-foaf3vyl 80 12 a a DT cord-004775-foaf3vyl 80 13 second second JJ cord-004775-foaf3vyl 80 14 virus virus NN cord-004775-foaf3vyl 80 15 specific specific JJ cord-004775-foaf3vyl 80 16 peak peak NN cord-004775-foaf3vyl 80 17 of of IN cord-004775-foaf3vyl 80 18 slower slow JJR cord-004775-foaf3vyl 80 19 sedimentation sedimentation NN cord-004775-foaf3vyl 80 20 ( ( -LRB- cord-004775-foaf3vyl 80 21 50 50 CD cord-004775-foaf3vyl 80 22 to to TO cord-004775-foaf3vyl 80 23 150 150 CD cord-004775-foaf3vyl 80 24 S S NNS cord-004775-foaf3vyl 80 25 ) ) -RRB- cord-004775-foaf3vyl 80 26 was be VBD cord-004775-foaf3vyl 80 27 detected detect VBN cord-004775-foaf3vyl 80 28 in in IN cord-004775-foaf3vyl 80 29 isokinetie isokinetie NN cord-004775-foaf3vyl 80 30 sucrose sucrose NN cord-004775-foaf3vyl 80 31 gradients gradient NNS cord-004775-foaf3vyl 80 32 of of IN cord-004775-foaf3vyl 80 33 BEV BEV NNP cord-004775-foaf3vyl 80 34 ; ; : cord-004775-foaf3vyl 80 35 these these DT cord-004775-foaf3vyl 80 36 particles particle NNS cord-004775-foaf3vyl 80 37 contained contain VBD cord-004775-foaf3vyl 80 38 smaller small JJR cord-004775-foaf3vyl 80 39 virus virus NN cord-004775-foaf3vyl 80 40 specific specific JJ cord-004775-foaf3vyl 80 41 RNA RNA NNP cord-004775-foaf3vyl 80 42 molecules molecule NNS cord-004775-foaf3vyl 80 43 and and CC cord-004775-foaf3vyl 80 44 the the DT cord-004775-foaf3vyl 80 45 22 22 CD cord-004775-foaf3vyl 80 46 kD kD NNP cord-004775-foaf3vyl 80 47 protein protein NN cord-004775-foaf3vyl 80 48 . . . cord-004775-foaf3vyl 81 1 They -PRON- PRP cord-004775-foaf3vyl 81 2 were be VBD cord-004775-foaf3vyl 81 3 non non JJ cord-004775-foaf3vyl 81 4 - - JJ cord-004775-foaf3vyl 81 5 infectious infectious JJ cord-004775-foaf3vyl 81 6 and and CC cord-004775-foaf3vyl 81 7 are be VBP cord-004775-foaf3vyl 81 8 probably probably RB cord-004775-foaf3vyl 81 9 non non JJ cord-004775-foaf3vyl 81 10 - - JJ cord-004775-foaf3vyl 81 11 interfering interfering JJ cord-004775-foaf3vyl 81 12 . . . cord-004775-foaf3vyl 82 1 Also also RB cord-004775-foaf3vyl 82 2 in in IN cord-004775-foaf3vyl 82 3 BI%V BI%V NNS cord-004775-foaf3vyl 82 4 2 2 CD cord-004775-foaf3vyl 82 5 preparations preparation NNS cord-004775-foaf3vyl 82 6 a a DT cord-004775-foaf3vyl 82 7 second second JJ cord-004775-foaf3vyl 82 8 peak peak NN cord-004775-foaf3vyl 82 9 ( ( -LRB- cord-004775-foaf3vyl 82 10 90 90 CD cord-004775-foaf3vyl 82 11 S s NN cord-004775-foaf3vyl 82 12 ) ) -RRB- cord-004775-foaf3vyl 82 13 with with IN cord-004775-foaf3vyl 82 14 a a DT cord-004775-foaf3vyl 82 15 hemagglutinating hemagglutinate VBG cord-004775-foaf3vyl 82 16 activity activity NN cord-004775-foaf3vyl 82 17 was be VBD cord-004775-foaf3vyl 82 18 encountered encounter VBN cord-004775-foaf3vyl 82 19 . . . cord-004775-foaf3vyl 83 1 Nature nature NN cord-004775-foaf3vyl 83 2 and and CC cord-004775-foaf3vyl 83 3 significance significance NN cord-004775-foaf3vyl 83 4 of of IN cord-004775-foaf3vyl 83 5 these these DT cord-004775-foaf3vyl 83 6 subviral subviral JJ cord-004775-foaf3vyl 83 7 particles particle NNS cord-004775-foaf3vyl 83 8 require require VBP cord-004775-foaf3vyl 83 9 further further JJ cord-004775-foaf3vyl 83 10 study study NN cord-004775-foaf3vyl 83 11 . . . cord-004775-foaf3vyl 84 1 t t NNP cord-004775-foaf3vyl 84 2 ~ ~ NFP cord-004775-foaf3vyl 84 3 esistanee esistanee RB cord-004775-foaf3vyl 84 4 BEV BEV NNP cord-004775-foaf3vyl 84 5 is be VBZ cord-004775-foaf3vyl 84 6 readily readily RB cord-004775-foaf3vyl 84 7 inactivated inactivate VBN cord-004775-foaf3vyl 84 8 by by IN cord-004775-foaf3vyl 84 9 heat heat NN cord-004775-foaf3vyl 84 10 but but CC cord-004775-foaf3vyl 84 11 well well RB cord-004775-foaf3vyl 84 12 preserved preserve VBN cord-004775-foaf3vyl 84 13 if if IN cord-004775-foaf3vyl 84 14 stored store VBN cord-004775-foaf3vyl 84 15 at at IN cord-004775-foaf3vyl 84 16 temperatures temperature NNS cord-004775-foaf3vyl 84 17 below below IN cord-004775-foaf3vyl 84 18 -20 -20 CD cord-004775-foaf3vyl 84 19 ° ° NNP cord-004775-foaf3vyl 84 20 C C NNP cord-004775-foaf3vyl 84 21 ( ( -LRB- cord-004775-foaf3vyl 84 22 16 16 CD cord-004775-foaf3vyl 84 23 ) ) -RRB- cord-004775-foaf3vyl 84 24 . . . cord-004775-foaf3vyl 85 1 Desiccation desiccation NN cord-004775-foaf3vyl 85 2 and and CC cord-004775-foaf3vyl 85 3 freeze freeze NN cord-004775-foaf3vyl 85 4 - - HYPH cord-004775-foaf3vyl 85 5 drying drying NN cord-004775-foaf3vyl 85 6 resulted result VBD cord-004775-foaf3vyl 85 7 in in IN cord-004775-foaf3vyl 85 8 insignificant insignificant JJ cord-004775-foaf3vyl 85 9 losses loss NNS cord-004775-foaf3vyl 85 10 of of IN cord-004775-foaf3vyl 85 11 infectivity infectivity NN cord-004775-foaf3vyl 85 12 . . . cord-004775-foaf3vyl 86 1 BEV BEV NNP cord-004775-foaf3vyl 86 2 is be VBZ cord-004775-foaf3vyl 86 3 very very RB cord-004775-foaf3vyl 86 4 sensitive sensitive JJ cord-004775-foaf3vyl 86 5 to to IN cord-004775-foaf3vyl 86 6 LVV LVV NNP cord-004775-foaf3vyl 86 7 - - HYPH cord-004775-foaf3vyl 86 8 ix'raditation ix'raditation NNP cord-004775-foaf3vyl 86 9 . . . cord-004775-foaf3vyl 87 1 A a DT cord-004775-foaf3vyl 87 2 high high JJ cord-004775-foaf3vyl 87 3 stability stability NN cord-004775-foaf3vyl 87 4 to to IN cord-004775-foaf3vyl 87 5 extreme extreme JJ cord-004775-foaf3vyl 87 6 hydrogen hydrogen NN cord-004775-foaf3vyl 87 7 ion ion NN cord-004775-foaf3vyl 87 8 concentrations concentration NNS cord-004775-foaf3vyl 87 9 was be VBD cord-004775-foaf3vyl 87 10 noted note VBN cord-004775-foaf3vyl 87 11 ; ; : cord-004775-foaf3vyl 87 12 infectivity infectivity NN cord-004775-foaf3vyl 87 13 titers titer NNS cord-004775-foaf3vyl 87 14 remained remain VBD cord-004775-foaf3vyl 87 15 unchanged unchanged JJ cord-004775-foaf3vyl 87 16 in in IN cord-004775-foaf3vyl 87 17 a a DT cord-004775-foaf3vyl 87 18 pH ph NN cord-004775-foaf3vyl 87 19 range range NN cord-004775-foaf3vyl 87 20 between between IN cord-004775-foaf3vyl 87 21 2.5 2.5 CD cord-004775-foaf3vyl 87 22 to to IN cord-004775-foaf3vyl 87 23 10.3 10.3 CD cord-004775-foaf3vyl 87 24 . . . cord-004775-foaf3vyl 88 1 Pronase Pronase NNP cord-004775-foaf3vyl 88 2 and and CC cord-004775-foaf3vyl 88 3 B. B. NNP cord-004775-foaf3vyl 88 4 subtilis subtilis NN cord-004775-foaf3vyl 88 5 proteinase proteinase NN cord-004775-foaf3vyl 88 6 reduced reduce VBD cord-004775-foaf3vyl 88 7 BEV BEV NNP cord-004775-foaf3vyl 88 8 virus virus NN cord-004775-foaf3vyl 88 9 infectivity infectivity NN cord-004775-foaf3vyl 88 10 whereas whereas IN cord-004775-foaf3vyl 88 11 treatment treatment NN cord-004775-foaf3vyl 88 12 with with IN cord-004775-foaf3vyl 88 13 trypsin trypsin NN cord-004775-foaf3vyl 88 14 and and CC cord-004775-foaf3vyl 88 15 chymotrypsin chymotrypsin NNP cord-004775-foaf3vyl 88 16 remained remain VBD cord-004775-foaf3vyl 88 17 without without IN cord-004775-foaf3vyl 88 18 effect effect NN cord-004775-foaf3vyl 88 19 . . . cord-004775-foaf3vyl 89 1 Neither neither DT cord-004775-foaf3vyl 89 2 phospholipase phospholipase NN cord-004775-foaf3vyl 89 3 C c NN cord-004775-foaf3vyl 89 4 , , , cord-004775-foaf3vyl 89 5 1%Nase 1%nase CD cord-004775-foaf3vyl 89 6 nor nor CC cord-004775-foaf3vyl 89 7 DOC doc NN cord-004775-foaf3vyl 89 8 ( ( -LRB- cord-004775-foaf3vyl 89 9 0.1 0.1 CD cord-004775-foaf3vyl 89 10 per per IN cord-004775-foaf3vyl 89 11 cent cent NN cord-004775-foaf3vyl 89 12 ) ) -RRB- cord-004775-foaf3vyl 89 13 affected affect VBD cord-004775-foaf3vyl 89 14 the the DT cord-004775-foaf3vyl 89 15 titer titer NN cord-004775-foaf3vyl 89 16 of of IN cord-004775-foaf3vyl 89 17 purified purify VBN cord-004775-foaf3vyl 89 18 BEV BEV NNP cord-004775-foaf3vyl 89 19 preparations preparation NNS cord-004775-foaf3vyl 89 20 . . . cord-004775-foaf3vyl 90 1 Triton Triton NNP cord-004775-foaf3vyl 90 2 X-100 x-100 NN cord-004775-foaf3vyl 90 3 in in IN cord-004775-foaf3vyl 90 4 contrast contrast NN cord-004775-foaf3vyl 90 5 , , , cord-004775-foaf3vyl 90 6 lead lead VBP cord-004775-foaf3vyl 90 7 to to IN cord-004775-foaf3vyl 90 8 rapid rapid JJ cord-004775-foaf3vyl 90 9 inactivation inactivation NN cord-004775-foaf3vyl 90 10 with with IN cord-004775-foaf3vyl 90 11 a a DT cord-004775-foaf3vyl 90 12 constant constant JJ cord-004775-foaf3vyl 90 13 level level NN cord-004775-foaf3vyl 90 14 of of IN cord-004775-foaf3vyl 90 15 residual residual JJ cord-004775-foaf3vyl 90 16 infectivity infectivity NN cord-004775-foaf3vyl 90 17 . . . cord-004775-foaf3vyl 91 1 Organic organic JJ cord-004775-foaf3vyl 91 2 solvents solvent NNS cord-004775-foaf3vyl 91 3 and and CC cord-004775-foaf3vyl 91 4 formalin formalin NN cord-004775-foaf3vyl 91 5 destroyed destroy VBD cord-004775-foaf3vyl 91 6 the the DT cord-004775-foaf3vyl 91 7 viral viral JJ cord-004775-foaf3vyl 91 8 infectivity infectivity NN cord-004775-foaf3vyl 91 9 completely completely RB cord-004775-foaf3vyl 91 10 . . . cord-004775-foaf3vyl 92 1 In in IN cord-004775-foaf3vyl 92 2 vivo vivo NN cord-004775-foaf3vyl 92 3 : : : cord-004775-foaf3vyl 92 4 BRV BRV NNP cord-004775-foaf3vyl 92 5 in in IN cord-004775-foaf3vyl 92 6 calves calf NNS cord-004775-foaf3vyl 92 7 was be VBD cord-004775-foaf3vyl 92 8 shown show VBN cord-004775-foaf3vyl 92 9 by by IN cord-004775-foaf3vyl 92 10 IF IF NNP cord-004775-foaf3vyl 92 11 and and CC cord-004775-foaf3vyl 92 12 EM EM NNP cord-004775-foaf3vyl 92 13 to to TO cord-004775-foaf3vyl 92 14 replicate replicate VB cord-004775-foaf3vyl 92 15 in in IN cord-004775-foaf3vyl 92 16 epithelial epithelial JJ cord-004775-foaf3vyl 92 17 cells cell NNS cord-004775-foaf3vyl 92 18 of of IN cord-004775-foaf3vyl 92 19 the the DT cord-004775-foaf3vyl 92 20 colon colon NN cord-004775-foaf3vyl 92 21 , , , cord-004775-foaf3vyl 92 22 the the DT cord-004775-foaf3vyl 92 23 caudal caudal JJ cord-004775-foaf3vyl 92 24 part part NN cord-004775-foaf3vyl 92 25 of of IN cord-004775-foaf3vyl 92 26 the the DT cord-004775-foaf3vyl 92 27 jejunum jejunum NNS cord-004775-foaf3vyl 92 28 and and CC cord-004775-foaf3vyl 92 29 the the DT cord-004775-foaf3vyl 92 30 ileum ileum NN cord-004775-foaf3vyl 92 31 . . . cord-004775-foaf3vyl 93 1 No no DT cord-004775-foaf3vyl 93 2 viral viral JJ cord-004775-foaf3vyl 93 3 antigen antigen NN cord-004775-foaf3vyl 93 4 was be VBD cord-004775-foaf3vyl 93 5 discovered discover VBN cord-004775-foaf3vyl 93 6 in in IN cord-004775-foaf3vyl 93 7 the the DT cord-004775-foaf3vyl 93 8 epithelium epithelium NN cord-004775-foaf3vyl 93 9 of of IN cord-004775-foaf3vyl 93 10 the the DT cord-004775-foaf3vyl 93 11 anterior anterior JJ cord-004775-foaf3vyl 93 12 part part NN cord-004775-foaf3vyl 93 13 of of IN cord-004775-foaf3vyl 93 14 the the DT cord-004775-foaf3vyl 93 15 jejunum jejunum NNS cord-004775-foaf3vyl 93 16 nor nor CC cord-004775-foaf3vyl 93 17 in in IN cord-004775-foaf3vyl 93 18 subepithelial subepithelial JJ cord-004775-foaf3vyl 93 19 tissue tissue NN cord-004775-foaf3vyl 93 20 . . . cord-004775-foaf3vyl 94 1 Cells cell NNS cord-004775-foaf3vyl 94 2 of of IN cord-004775-foaf3vyl 94 3 both both CC cord-004775-foaf3vyl 94 4 the the DT cord-004775-foaf3vyl 94 5 crypts crypt NNS cord-004775-foaf3vyl 94 6 and and CC cord-004775-foaf3vyl 94 7 villi villi NN cord-004775-foaf3vyl 94 8 in in IN cord-004775-foaf3vyl 94 9 mid mid NN cord-004775-foaf3vyl 94 10 to to TO cord-004775-foaf3vyl 94 11 lower lower VB cord-004775-foaf3vyl 94 12 jejunum jejunum NNS cord-004775-foaf3vyl 94 13 and and CC cord-004775-foaf3vyl 94 14 ileum ileum NN cord-004775-foaf3vyl 94 15 are be VBP cord-004775-foaf3vyl 94 16 infected infect VBN cord-004775-foaf3vyl 94 17 as as IN cord-004775-foaf3vyl 94 18 are be VBP cord-004775-foaf3vyl 94 19 most most JJS cord-004775-foaf3vyl 94 20 cells cell NNS cord-004775-foaf3vyl 94 21 of of IN cord-004775-foaf3vyl 94 22 the the DT cord-004775-foaf3vyl 94 23 large large JJ cord-004775-foaf3vyl 94 24 intestine intestine NN cord-004775-foaf3vyl 94 25 ( ( -LRB- cord-004775-foaf3vyl 94 26 1 1 CD cord-004775-foaf3vyl 94 27 , , , cord-004775-foaf3vyl 94 28 4 4 CD cord-004775-foaf3vyl 94 29 , , , cord-004775-foaf3vyl 94 30 10 10 CD cord-004775-foaf3vyl 94 31 , , , cord-004775-foaf3vyl 94 32 11 11 CD cord-004775-foaf3vyl 94 33 , , , cord-004775-foaf3vyl 94 34 12 12 CD cord-004775-foaf3vyl 94 35 ) ) -RRB- cord-004775-foaf3vyl 94 36 . . . cord-004775-foaf3vyl 95 1 In in IN cord-004775-foaf3vyl 95 2 vitro vitro FW cord-004775-foaf3vyl 95 3 : : : cord-004775-foaf3vyl 95 4 BEV BEV NNP cord-004775-foaf3vyl 95 5 , , , cord-004775-foaf3vyl 95 6 originally originally RB cord-004775-foaf3vyl 95 7 isolated isolate VBN cord-004775-foaf3vyl 95 8 in in IN cord-004775-foaf3vyl 95 9 secondary secondary JJ cord-004775-foaf3vyl 95 10 horse horse NN cord-004775-foaf3vyl 95 11 kidney kidney NN cord-004775-foaf3vyl 95 12 cells cell NNS cord-004775-foaf3vyl 95 13 , , , cord-004775-foaf3vyl 95 14 can can MD cord-004775-foaf3vyl 95 15 be be VB cord-004775-foaf3vyl 95 16 propagated propagate VBN cord-004775-foaf3vyl 95 17 in in IN cord-004775-foaf3vyl 95 18 cell cell NN cord-004775-foaf3vyl 95 19 cultures culture NNS cord-004775-foaf3vyl 95 20 of of IN cord-004775-foaf3vyl 95 21 equine equine JJ cord-004775-foaf3vyl 95 22 origin origin NN cord-004775-foaf3vyl 95 23 ( ( -LRB- cord-004775-foaf3vyl 95 24 horse horse NN cord-004775-foaf3vyl 95 25 kidney kidney NN cord-004775-foaf3vyl 95 26 , , , cord-004775-foaf3vyl 95 27 embryonic embryonic JJ cord-004775-foaf3vyl 95 28 horse horse NN cord-004775-foaf3vyl 95 29 lung lung NN cord-004775-foaf3vyl 95 30 , , , cord-004775-foaf3vyl 95 31 embryonic embryonic JJ cord-004775-foaf3vyl 95 32 mule mule JJ cord-004775-foaf3vyl 95 33 skin skin NN cord-004775-foaf3vyl 95 34 and and CC cord-004775-foaf3vyl 95 35 equine equine JJ cord-004775-foaf3vyl 95 36 dermal dermal JJ cord-004775-foaf3vyl 95 37 cells cell NNS cord-004775-foaf3vyl 95 38 ) ) -RRB- cord-004775-foaf3vyl 95 39 ( ( -LRB- cord-004775-foaf3vyl 95 40 2 2 CD cord-004775-foaf3vyl 95 41 ) ) -RRB- cord-004775-foaf3vyl 95 42 . . . cord-004775-foaf3vyl 96 1 Attempts attempt NNS cord-004775-foaf3vyl 96 2 to to TO cord-004775-foaf3vyl 96 3 grow grow VB cord-004775-foaf3vyl 96 4 BEV BEV NNP cord-004775-foaf3vyl 96 5 in in IN cord-004775-foaf3vyl 96 6 cells cell NNS cord-004775-foaf3vyl 96 7 originating originate VBG cord-004775-foaf3vyl 96 8 from from IN cord-004775-foaf3vyl 96 9 man man NN cord-004775-foaf3vyl 96 10 , , , cord-004775-foaf3vyl 96 11 monkey monkey NN cord-004775-foaf3vyl 96 12 , , , cord-004775-foaf3vyl 96 13 cattle cattle NNS cord-004775-foaf3vyl 96 14 , , , cord-004775-foaf3vyl 96 15 pig pig NN cord-004775-foaf3vyl 96 16 , , , cord-004775-foaf3vyl 96 17 rabbit rabbit NN cord-004775-foaf3vyl 96 18 , , , cord-004775-foaf3vyl 96 19 mouse mouse NN cord-004775-foaf3vyl 96 20 , , , cord-004775-foaf3vyl 96 21 hamster hamster NN cord-004775-foaf3vyl 96 22 , , , cord-004775-foaf3vyl 96 23 were be VBD cord-004775-foaf3vyl 96 24 unsuccessful unsuccessful JJ cord-004775-foaf3vyl 97 1 ( ( -LRB- cord-004775-foaf3vyl 97 2 WEIss WEIss NNP cord-004775-foaf3vyl 97 3 , , , cord-004775-foaf3vyl 97 4 unpublished unpublished JJ cord-004775-foaf3vyl 97 5 results result NNS cord-004775-foaf3vyl 97 6 ) ) -RRB- cord-004775-foaf3vyl 97 7 . . . cord-004775-foaf3vyl 98 1 Neither neither CC cord-004775-foaf3vyl 98 2 BRV BRV NNP cord-004775-foaf3vyl 98 3 nor nor CC cord-004775-foaf3vyl 98 4 the the DT cord-004775-foaf3vyl 98 5 human human JJ cord-004775-foaf3vyl 98 6 torovirus torovirus NN cord-004775-foaf3vyl 98 7 particles particle NNS cord-004775-foaf3vyl 98 8 could could MD cord-004775-foaf3vyl 98 9 be be VB cord-004775-foaf3vyl 98 10 adapted adapt VBN cord-004775-foaf3vyl 98 11 to to TO cord-004775-foaf3vyl 98 12 gro gro VB cord-004775-foaf3vyl 98 13 ~ ~ NFP cord-004775-foaf3vyl 98 14 h h NN cord-004775-foaf3vyl 98 15 in in IN cord-004775-foaf3vyl 98 16 culture culture NN cord-004775-foaf3vyl 98 17 so so RB cord-004775-foaf3vyl 98 18 far far RB cord-004775-foaf3vyl 98 19 ( ( -LRB- cord-004775-foaf3vyl 98 20 1 1 CD cord-004775-foaf3vyl 98 21 , , , cord-004775-foaf3vyl 98 22 8) 8) NNP cord-004775-foaf3vyl 98 23 . . . cord-004775-foaf3vyl 99 1 Hemagglutination Hemagglutination NNP cord-004775-foaf3vyl 99 2 BRV BRV NNP cord-004775-foaf3vyl 99 3 and and CC cord-004775-foaf3vyl 99 4 BEV BEV NNP cord-004775-foaf3vyl 99 5 possess possess VBP cord-004775-foaf3vyl 99 6 hemagglutinating hemagglutinate VBG cord-004775-foaf3vyl 99 7 activity activity NN cord-004775-foaf3vyl 99 8 whereas whereas IN cord-004775-foaf3vyl 99 9 no no DT cord-004775-foaf3vyl 99 10 such such JJ cord-004775-foaf3vyl 99 11 property property NN cord-004775-foaf3vyl 99 12 could could MD cord-004775-foaf3vyl 99 13 be be VB cord-004775-foaf3vyl 99 14 demonstrated demonstrate VBN cord-004775-foaf3vyl 99 15 for for IN cord-004775-foaf3vyl 99 16 the the DT cord-004775-foaf3vyl 99 17 human human JJ cord-004775-foaf3vyl 99 18 torovirus torovirus NNP cord-004775-foaf3vyl 99 19 particles particle NNS cord-004775-foaf3vyl 99 20 up up RP cord-004775-foaf3vyl 99 21 to to IN cord-004775-foaf3vyl 99 22 now now RB cord-004775-foaf3vyl 99 23 . . . cord-004775-foaf3vyl 100 1 Hemagglutination Hemagglutination NNP cord-004775-foaf3vyl 100 2 of of IN cord-004775-foaf3vyl 100 3 Bt Bt NNP cord-004775-foaf3vyl 101 1 ~V ~V NFP cord-004775-foaf3vyl 101 2 was be VBD cord-004775-foaf3vyl 101 3 only only RB cord-004775-foaf3vyl 101 4 obtained obtain VBN cord-004775-foaf3vyl 101 5 with with IN cord-004775-foaf3vyl 101 6 mouse mouse NN cord-004775-foaf3vyl 101 7 and and CC cord-004775-foaf3vyl 101 8 rat rat NN cord-004775-foaf3vyl 101 9 erythrocytes erythrocyte NNS cord-004775-foaf3vyl 101 10 ( ( -LRB- cord-004775-foaf3vyl 101 11 ECs ECs NNP cord-004775-foaf3vyl 101 12 ) ) -RRB- cord-004775-foaf3vyl 101 13 . . . cord-004775-foaf3vyl 102 1 All all DT cord-004775-foaf3vyl 102 2 attempts attempt NNS cord-004775-foaf3vyl 102 3 with with IN cord-004775-foaf3vyl 102 4 ECs ec NNS cord-004775-foaf3vyl 102 5 from from IN cord-004775-foaf3vyl 102 6 other other JJ cord-004775-foaf3vyl 102 7 species specie NNS cord-004775-foaf3vyl 102 8 ( ( -LRB- cord-004775-foaf3vyl 102 9 human human JJ cord-004775-foaf3vyl 102 10 group group NN cord-004775-foaf3vyl 102 11 O o NN cord-004775-foaf3vyl 102 12 , , , cord-004775-foaf3vyl 102 13 bovine bovine NN cord-004775-foaf3vyl 102 14 , , , cord-004775-foaf3vyl 102 15 hamster hamster NN cord-004775-foaf3vyl 102 16 , , , cord-004775-foaf3vyl 102 17 guinea guinea NN cord-004775-foaf3vyl 102 18 pig pig NN cord-004775-foaf3vyl 102 19 , , , cord-004775-foaf3vyl 102 20 chicken chicken NN cord-004775-foaf3vyl 102 21 , , , cord-004775-foaf3vyl 102 22 turkey turkey NN cord-004775-foaf3vyl 102 23 , , , cord-004775-foaf3vyl 102 24 goose goose NN cord-004775-foaf3vyl 102 25 ) ) -RRB- cord-004775-foaf3vyl 102 26 remained remain VBD cord-004775-foaf3vyl 102 27 without without IN cord-004775-foaf3vyl 102 28 success success NN cord-004775-foaf3vyl 102 29 ( ( -LRB- cord-004775-foaf3vyl 102 30 1 1 CD cord-004775-foaf3vyl 102 31 ) ) -RRB- cord-004775-foaf3vyl 102 32 . . . cord-004775-foaf3vyl 103 1 In in IN cord-004775-foaf3vyl 103 2 contrast contrast NN cord-004775-foaf3vyl 103 3 , , , cord-004775-foaf3vyl 103 4 BEV BEV NNP cord-004775-foaf3vyl 103 5 agglutinates agglutinates NNPS cord-004775-foaf3vyl 103 6 ( ( -LRB- cord-004775-foaf3vyl 103 7 in in IN cord-004775-foaf3vyl 103 8 decreasing decrease VBG cord-004775-foaf3vyl 103 9 order order NN cord-004775-foaf3vyl 103 10 ) ) -RRB- cord-004775-foaf3vyl 103 11 ECs ec NNS cord-004775-foaf3vyl 103 12 from from IN cord-004775-foaf3vyl 103 13 human human JJ cord-004775-foaf3vyl 103 14 ( ( -LRB- cord-004775-foaf3vyl 103 15 group group NN cord-004775-foaf3vyl 103 16 0 0 CD cord-004775-foaf3vyl 103 17 ) ) -RRB- cord-004775-foaf3vyl 103 18 , , , cord-004775-foaf3vyl 103 19 rabbit rabbit NN cord-004775-foaf3vyl 103 20 and and CC cord-004775-foaf3vyl 103 21 guinea guinea NN cord-004775-foaf3vyl 103 22 pig pig NN cord-004775-foaf3vyl 104 1 but but CC cord-004775-foaf3vyl 104 2 not not RB cord-004775-foaf3vyl 104 3 from from IN cord-004775-foaf3vyl 104 4 rat rat NN cord-004775-foaf3vyl 104 5 and and CC cord-004775-foaf3vyl 104 6 mouse mouse NN cord-004775-foaf3vyl 104 7 or or CC cord-004775-foaf3vyl 104 8 other other JJ cord-004775-foaf3vyl 104 9 ( ( -LRB- cord-004775-foaf3vyl 104 10 21 21 CD cord-004775-foaf3vyl 104 11 ) ) -RRB- cord-004775-foaf3vyl 104 12 . . . cord-004775-foaf3vyl 105 1 By by IN cord-004775-foaf3vyl 105 2 electron electron NN cord-004775-foaf3vyl 105 3 microscopy microscopy NN cord-004775-foaf3vyl 105 4 BEV BEV NNP cord-004775-foaf3vyl 105 5 particles particle NNS cord-004775-foaf3vyl 105 6 were be VBD cord-004775-foaf3vyl 105 7 shown show VBN cord-004775-foaf3vyl 105 8 to to TO cord-004775-foaf3vyl 105 9 bind bind VB cord-004775-foaf3vyl 105 10 with with IN cord-004775-foaf3vyl 105 11 the the DT cord-004775-foaf3vyl 105 12 peplomers peplomer NNS cord-004775-foaf3vyl 105 13 to to IN cord-004775-foaf3vyl 105 14 the the DT cord-004775-foaf3vyl 105 15 EC EC NNP cord-004775-foaf3vyl 105 16 surface surface NN cord-004775-foaf3vyl 106 1 ( ( -LRB- cord-004775-foaf3vyl 106 2 Fig Fig NNP cord-004775-foaf3vyl 106 3 . . NNP cord-004775-foaf3vyl 106 4 5 5 CD cord-004775-foaf3vyl 106 5 ) ) -RRB- cord-004775-foaf3vyl 106 6 . . . cord-004775-foaf3vyl 107 1 Evidence evidence NN cord-004775-foaf3vyl 107 2 was be VBD cord-004775-foaf3vyl 107 3 obtained obtain VBN cord-004775-foaf3vyl 107 4 that that IN cord-004775-foaf3vyl 107 5 , , , cord-004775-foaf3vyl 107 6 the the DT cord-004775-foaf3vyl 107 7 human human JJ cord-004775-foaf3vyl 107 8 erythroe3~e erythroe3~e NNP cord-004775-foaf3vyl 107 9 receptors receptor NNS cord-004775-foaf3vyl 107 10 for for IN cord-004775-foaf3vyl 107 11 BEV BEV NNP cord-004775-foaf3vyl 107 12 are be VBP cord-004775-foaf3vyl 107 13 glycoproteins glycoprotein NNS cord-004775-foaf3vyl 107 14 or or CC cord-004775-foaf3vyl 107 15 glyeolipids glyeolipid NNS cord-004775-foaf3vyl 107 16 . . . cord-004775-foaf3vyl 108 1 The the DT cord-004775-foaf3vyl 108 2 strain strain NN cord-004775-foaf3vyl 108 3 P p NN cord-004775-foaf3vyl 108 4 138/72 138/72 CD cord-004775-foaf3vyl 108 5 of of IN cord-004775-foaf3vyl 108 6 BEV BEV NNP cord-004775-foaf3vyl 108 7 is be VBZ cord-004775-foaf3vyl 108 8 the the DT cord-004775-foaf3vyl 108 9 only only JJ cord-004775-foaf3vyl 108 10 equine equine JJ cord-004775-foaf3vyl 108 11 torovirus torovirus NN cord-004775-foaf3vyl 108 12 strain strain NN cord-004775-foaf3vyl 108 13 isolated isolate VBN cord-004775-foaf3vyl 108 14 so so RB cord-004775-foaf3vyl 108 15 far far RB cord-004775-foaf3vyl 108 16 ( ( -LRB- cord-004775-foaf3vyl 108 17 2 2 CD cord-004775-foaf3vyl 108 18 ) ) -RRB- cord-004775-foaf3vyl 108 19 . . . cord-004775-foaf3vyl 109 1 In in IN cord-004775-foaf3vyl 109 2 contrast contrast NN cord-004775-foaf3vyl 109 3 several several JJ cord-004775-foaf3vyl 109 4 BRV BRV NNP cord-004775-foaf3vyl 109 5 isolates isolate NNS cord-004775-foaf3vyl 109 6 were be VBD cord-004775-foaf3vyl 109 7 obtained obtain VBN cord-004775-foaf3vyl 109 8 from from IN cord-004775-foaf3vyl 109 9 cattle cattle NNS cord-004775-foaf3vyl 109 10 . . . cord-004775-foaf3vyl 110 1 Three three CD cord-004775-foaf3vyl 110 2 of of IN cord-004775-foaf3vyl 110 3 them -PRON- PRP cord-004775-foaf3vyl 110 4 were be VBD cord-004775-foaf3vyl 110 5 compared compare VBN cord-004775-foaf3vyl 110 6 antigenically antigenically RB cord-004775-foaf3vyl 110 7 and and CC cord-004775-foaf3vyl 110 8 were be VBD cord-004775-foaf3vyl 110 9 found find VBN cord-004775-foaf3vyl 110 10 to to TO cord-004775-foaf3vyl 110 11 be be VB cord-004775-foaf3vyl 110 12 related relate VBN cord-004775-foaf3vyl 110 13 ( ( -LRB- cord-004775-foaf3vyl 110 14 17 17 CD cord-004775-foaf3vyl 110 15 ) ) -RRB- cord-004775-foaf3vyl 110 16 . . . cord-004775-foaf3vyl 111 1 No no DT cord-004775-foaf3vyl 111 2 distinction distinction NN cord-004775-foaf3vyl 111 3 between between IN cord-004775-foaf3vyl 111 4 them -PRON- PRP cord-004775-foaf3vyl 111 5 was be VBD cord-004775-foaf3vyl 111 6 noted note VBN cord-004775-foaf3vyl 111 7 in in IN cord-004775-foaf3vyl 111 8 immunofluorescence immunofluorescence NN cord-004775-foaf3vyl 111 9 ( ( -LRB- cord-004775-foaf3vyl 111 10 IF if NN cord-004775-foaf3vyl 111 11 ) ) -RRB- cord-004775-foaf3vyl 111 12 tests test NNS cord-004775-foaf3vyl 111 13 . . . cord-004775-foaf3vyl 112 1 On on IN cord-004775-foaf3vyl 112 2 the the DT cord-004775-foaf3vyl 112 3 basis basis NN cord-004775-foaf3vyl 112 4 of of IN cord-004775-foaf3vyl 112 5 results result NNS cord-004775-foaf3vyl 112 6 obtained obtain VBN cord-004775-foaf3vyl 112 7 in in IN cord-004775-foaf3vyl 112 8 hemagglutination hemagglutination NN cord-004775-foaf3vyl 112 9 inhibition inhibition NN cord-004775-foaf3vyl 112 10 ( ( -LRB- cord-004775-foaf3vyl 112 11 HI HI NNP cord-004775-foaf3vyl 112 12 ) ) -RRB- cord-004775-foaf3vyl 112 13 , , , cord-004775-foaf3vyl 112 14 enzymelinked enzymelinked JJ cord-004775-foaf3vyl 112 15 immunosorbent immunosorbent JJ cord-004775-foaf3vyl 112 16 assay assay NN cord-004775-foaf3vyl 112 17 ( ( -LRB- cord-004775-foaf3vyl 112 18 ELISA ELISA NNP cord-004775-foaf3vyl 112 19 ) ) -RRB- cord-004775-foaf3vyl 112 20 and and CC cord-004775-foaf3vyl 112 21 immunoelectron immunoelectron NNP cord-004775-foaf3vyl 112 22 microscopy microscopy NNP cord-004775-foaf3vyl 112 23 ( ( -LRB- cord-004775-foaf3vyl 112 24 IEM IEM NNP cord-004775-foaf3vyl 112 25 ) ) -RRB- cord-004775-foaf3vyl 112 26 however however RB cord-004775-foaf3vyl 112 27 , , , cord-004775-foaf3vyl 112 28 they -PRON- PRP cord-004775-foaf3vyl 112 29 were be VBD cord-004775-foaf3vyl 112 30 divided divide VBN cord-004775-foaf3vyl 112 31 into into IN cord-004775-foaf3vyl 112 32 2 2 CD cord-004775-foaf3vyl 112 33 serotypes serotype NNS cord-004775-foaf3vyl 112 34 : : : cord-004775-foaf3vyl 112 35 serotype serotype NN cord-004775-foaf3vyl 112 36 1 1 CD cord-004775-foaf3vyl 112 37 (= (= NNP cord-004775-foaf3vyl 112 38 Breda Breda NNP cord-004775-foaf3vyl 112 39 1 1 CD cord-004775-foaf3vyl 112 40 ) ) -RRB- cord-004775-foaf3vyl 112 41 is be VBZ cord-004775-foaf3vyl 112 42 represented represent VBN cord-004775-foaf3vyl 112 43 by by IN cord-004775-foaf3vyl 112 44 the the DT cord-004775-foaf3vyl 112 45 Iowa Iowa NNP cord-004775-foaf3vyl 112 46 isolate isolate VBP cord-004775-foaf3vyl 112 47 1 1 CD cord-004775-foaf3vyl 112 48 , , , cord-004775-foaf3vyl 112 49 serotype serotype NN cord-004775-foaf3vyl 112 50 2 2 CD cord-004775-foaf3vyl 112 51 (= (= NNP cord-004775-foaf3vyl 112 52 Breda Breda NNP cord-004775-foaf3vyl 112 53 2 2 CD cord-004775-foaf3vyl 112 54 ) ) -RRB- cord-004775-foaf3vyl 112 55 by by IN cord-004775-foaf3vyl 112 56 the the DT cord-004775-foaf3vyl 112 57 Ohio Ohio NNP cord-004775-foaf3vyl 112 58 isolate isolate NN cord-004775-foaf3vyl 112 59 and and CC cord-004775-foaf3vyl 112 60 the the DT cord-004775-foaf3vyl 112 61 Iowa Iowa NNP cord-004775-foaf3vyl 112 62 isola.te isola.te NNP cord-004775-foaf3vyl 112 63 2 2 CD cord-004775-foaf3vyl 112 64 . . . cord-004775-foaf3vyl 113 1 BEV BEV NNP cord-004775-foaf3vyl 113 2 and and CC cord-004775-foaf3vyl 113 3 BRV BRV NNP cord-004775-foaf3vyl 113 4 share share NN cord-004775-foaf3vyl 113 5 antigens antigen NNS cord-004775-foaf3vyl 113 6 as as IN cord-004775-foaf3vyl 113 7 evidenced evidence VBN cord-004775-foaf3vyl 113 8 by by IN cord-004775-foaf3vyl 113 9 cross cross NN cord-004775-foaf3vyl 113 10 reactions reaction NNS cord-004775-foaf3vyl 113 11 in in IN cord-004775-foaf3vyl 113 12 different different JJ cord-004775-foaf3vyl 113 13 , , , cord-004775-foaf3vyl 113 14 serological serological JJ cord-004775-foaf3vyl 113 15 tests test NNS cord-004775-foaf3vyl 113 16 . . . cord-004775-foaf3vyl 114 1 BEV BEV NNP cord-004775-foaf3vyl 114 2 preparations preparation NNS cord-004775-foaf3vyl 114 3 reacted react VBD cord-004775-foaf3vyl 114 4 in in IN cord-004775-foaf3vyl 114 5 seroneutrMization seroneutrMization NNP cord-004775-foaf3vyl 114 6 , , , cord-004775-foaf3vyl 114 7 ELISA ELISA NNP cord-004775-foaf3vyl 114 8 and and CC cord-004775-foaf3vyl 114 9 RIP RIP NNP cord-004775-foaf3vyl 114 10 with with IN cord-004775-foaf3vyl 114 11 bovine bovine JJ cord-004775-foaf3vyl 114 12 sera sera NNP cord-004775-foaf3vyl 114 13 ( ( -LRB- cord-004775-foaf3vyl 114 14 2 2 CD cord-004775-foaf3vyl 114 15 , , , cord-004775-foaf3vyl 114 16 14 14 CD cord-004775-foaf3vyl 114 17 ) ) -RRB- cord-004775-foaf3vyl 114 18 , , , cord-004775-foaf3vyl 114 19 and and CC cord-004775-foaf3vyl 114 20 positive positive JJ cord-004775-foaf3vyl 114 21 reactions reaction NNS cord-004775-foaf3vyl 114 22 were be VBD cord-004775-foaf3vyl 114 23 noted note VBN cord-004775-foaf3vyl 114 24 between between IN cord-004775-foaf3vyl 114 25 BRV BRV NNP cord-004775-foaf3vyl 114 26 antigens antigen NNS cord-004775-foaf3vyl 114 27 and and CC cord-004775-foaf3vyl 114 28 BEV BEV NNP cord-004775-foaf3vyl 114 29 antibodies antibody NNS cord-004775-foaf3vyl 114 30 in in IN cord-004775-foaf3vyl 114 31 IF IF NNP cord-004775-foaf3vyl 114 32 and and CC cord-004775-foaf3vyl 114 33 ELISA ELISA NNP cord-004775-foaf3vyl 114 34 but but CC cord-004775-foaf3vyl 114 35 not not RB cord-004775-foaf3vyl 114 36 in in IN cord-004775-foaf3vyl 114 37 a a DT cord-004775-foaf3vyl 114 38 HI HI NNP cord-004775-foaf3vyl 114 39 test test NN cord-004775-foaf3vyl 114 40 ( ( -LRB- cord-004775-foaf3vyl 114 41 WOODE woode NN cord-004775-foaf3vyl 114 42 , , , cord-004775-foaf3vyl 114 43 personal personal JJ cord-004775-foaf3vyl 114 44 communication communication NN cord-004775-foaf3vyl 114 45 ) ) -RRB- cord-004775-foaf3vyl 114 46 . . . cord-004775-foaf3vyl 115 1 A a DT cord-004775-foaf3vyl 115 2 mouse mouse NN cord-004775-foaf3vyl 115 3 serum serum NN cord-004775-foaf3vyl 115 4 raised raise VBD cord-004775-foaf3vyl 115 5 against against IN cord-004775-foaf3vyl 115 6 Breda Breda NNP cord-004775-foaf3vyl 115 7 2 2 CD cord-004775-foaf3vyl 115 8 and and CC cord-004775-foaf3vyl 115 9 known know VBN cord-004775-foaf3vyl 115 10 to to TO cord-004775-foaf3vyl 115 11 recognize recognize VB cord-004775-foaf3vyl 115 12 not not RB cord-004775-foaf3vyl 115 13 . . . cord-004775-foaf3vyl 116 1 only only RB cord-004775-foaf3vyl 116 2 the the DT cord-004775-foaf3vyl 116 3 homologous homologous JJ cord-004775-foaf3vyl 116 4 proteins protein NNS cord-004775-foaf3vyl 116 5 but but CC cord-004775-foaf3vyl 116 6 also also RB cord-004775-foaf3vyl 116 7 the the DT cord-004775-foaf3vyl 116 8 105 105 CD cord-004775-foaf3vyl 116 9 and and CC cord-004775-foaf3vyl 116 10 85 85 CD cord-004775-foaf3vyl 116 11 kD kd JJ cord-004775-foaf3vyl 116 12 proteins protein NNS cord-004775-foaf3vyl 116 13 of of IN cord-004775-foaf3vyl 116 14 the the DT cord-004775-foaf3vyl 116 15 heterologous heterologous JJ cord-004775-foaf3vyl 116 16 BRV BRV NNP cord-004775-foaf3vyl 116 17 1 1 CD cord-004775-foaf3vyl 116 18 in in IN cord-004775-foaf3vyl 116 19 RIP RIP NNP cord-004775-foaf3vyl 116 20 , , , cord-004775-foaf3vyl 116 21 inhibited inhibited JJ cord-004775-foaf3vyl 116 22 hemagglutination hemagglutination NN cord-004775-foaf3vyl 116 23 of of IN cord-004775-foaf3vyl 116 24 the the DT cord-004775-foaf3vyl 116 25 heterologous heterologous JJ cord-004775-foaf3vyl 116 26 serotype serotype NNP cord-004775-foaf3vyl 116 27 to to IN cord-004775-foaf3vyl 116 28 a a DT cord-004775-foaf3vyl 116 29 low low JJ cord-004775-foaf3vyl 116 30 but but CC cord-004775-foaf3vyl 116 31 significant significant JJ cord-004775-foaf3vyl 116 32 degree degree NN cord-004775-foaf3vyl 116 33 and and CC cord-004775-foaf3vyl 116 34 neutralized neutralize VBD cord-004775-foaf3vyl 116 35 the the DT cord-004775-foaf3vyl 116 36 infectivity infectivity NN cord-004775-foaf3vyl 116 37 of of IN cord-004775-foaf3vyl 116 38 BEV BEV NNP cord-004775-foaf3vyl 116 39 ( ( -LRB- cord-004775-foaf3vyl 116 40 15 15 CD cord-004775-foaf3vyl 116 41 ) ) -RRB- cord-004775-foaf3vyl 116 42 . . . cord-004775-foaf3vyl 117 1 Monoclonal monoclonal JJ cord-004775-foaf3vyl 117 2 antibodies antibody NNS cord-004775-foaf3vyl 117 3 produced produce VBN cord-004775-foaf3vyl 117 4 against against IN cord-004775-foaf3vyl 117 5 BEV BEV NNP cord-004775-foaf3vyl 117 6 and and CC cord-004775-foaf3vyl 117 7 recognizing recognize VBG cord-004775-foaf3vyl 117 8 the the DT cord-004775-foaf3vyl 117 9 7 7 CD cord-004775-foaf3vyl 117 10 5 5 CD cord-004775-foaf3vyl 117 11 -100 -100 NNS cord-004775-foaf3vyl 117 12 kD kd JJ cord-004775-foaf3vyl 117 13 protein protein NN cord-004775-foaf3vyl 117 14 in in IN cord-004775-foaf3vyl 117 15 RIP RIP NNP cord-004775-foaf3vyl 117 16 showed show VBD cord-004775-foaf3vyl 117 17 neutralizing neutralize VBG cord-004775-foaf3vyl 117 18 and and CC cord-004775-foaf3vyl 117 19 hemagglutination hemagglutination NN cord-004775-foaf3vyl 117 20 inhibition inhibition NN cord-004775-foaf3vyl 117 21 properties property NNS cord-004775-foaf3vyl 117 22 ( ( -LRB- cord-004775-foaf3vyl 117 23 20 20 CD cord-004775-foaf3vyl 117 24 ) ) -RRB- cord-004775-foaf3vyl 117 25 ( ( -LRB- cord-004775-foaf3vyl 117 26 Fig Fig NNP cord-004775-foaf3vyl 117 27 . . NNP cord-004775-foaf3vyl 117 28 4 4 CD cord-004775-foaf3vyl 117 29 ) ) -RRB- cord-004775-foaf3vyl 117 30 . . . cord-004775-foaf3vyl 118 1 From from IN cord-004775-foaf3vyl 118 2 these these DT cord-004775-foaf3vyl 118 3 data datum NNS cord-004775-foaf3vyl 118 4 and and CC cord-004775-foaf3vyl 118 5 the the DT cord-004775-foaf3vyl 118 6 observation observation NN cord-004775-foaf3vyl 118 7 that that IN cord-004775-foaf3vyl 118 8 a a DT cord-004775-foaf3vyl 118 9 horse horse NN cord-004775-foaf3vyl 118 10 field field NN cord-004775-foaf3vyl 118 11 serum serum NN cord-004775-foaf3vyl 118 12 with with IN cord-004775-foaf3vyl 118 13 a a DT cord-004775-foaf3vyl 118 14 high high JJ cord-004775-foaf3vyl 118 15 neutralizing neutralize VBG cord-004775-foaf3vyl 118 16 activity activity NN cord-004775-foaf3vyl 118 17 against against IN cord-004775-foaf3vyl 118 18 BEV BEV NNP cord-004775-foaf3vyl 118 19 preferentially preferentially RB cord-004775-foaf3vyl 118 20 recognized recognize VBD cord-004775-foaf3vyl 118 21 the the DT cord-004775-foaf3vyl 118 22 75 75 CD cord-004775-foaf3vyl 118 23 - - SYM cord-004775-foaf3vyl 118 24 100 100 CD cord-004775-foaf3vyl 118 25 kD kD NNP cord-004775-foaf3vyl 118 26 protein protein NN cord-004775-foaf3vyl 118 27 ( ( -LRB- cord-004775-foaf3vyl 118 28 14 14 CD cord-004775-foaf3vyl 118 29 ) ) -RRB- cord-004775-foaf3vyl 118 30 it -PRON- PRP cord-004775-foaf3vyl 118 31 is be VBZ cord-004775-foaf3vyl 118 32 concluded conclude VBN cord-004775-foaf3vyl 118 33 that that IN cord-004775-foaf3vyl 118 34 the the DT cord-004775-foaf3vyl 118 35 erossreaeting erossreaete VBG cord-004775-foaf3vyl 118 36 antigens antigen NNS cord-004775-foaf3vyl 118 37 are be VBP cord-004775-foaf3vyl 118 38 represented represent VBN cord-004775-foaf3vyl 118 39 by by IN cord-004775-foaf3vyl 118 40 the the DT cord-004775-foaf3vyl 118 41 high high JJ cord-004775-foaf3vyl 118 42 mol mol NN cord-004775-foaf3vyl 118 43 . . . cord-004775-foaf3vyl 119 1 wt wt NN cord-004775-foaf3vyl 119 2 glyeoproteins glyeoprotein NNS cord-004775-foaf3vyl 119 3 . . . cord-004775-foaf3vyl 120 1 Their -PRON- PRP$ cord-004775-foaf3vyl 120 2 apparent apparent JJ cord-004775-foaf3vyl 120 3 involvement involvement NN cord-004775-foaf3vyl 120 4 in in IN cord-004775-foaf3vyl 120 5 neutrMization neutrmization NN cord-004775-foaf3vyl 120 6 and and CC cord-004775-foaf3vyl 120 7 ttI ttI NNP cord-004775-foaf3vyl 120 8 makes make VBZ cord-004775-foaf3vyl 120 9 them -PRON- PRP cord-004775-foaf3vyl 120 10 candidate candidate NN cord-004775-foaf3vyl 120 11 for for IN cord-004775-foaf3vyl 120 12 peplomer peplomer JJ cord-004775-foaf3vyl 120 13 proteins protein NNS cord-004775-foaf3vyl 120 14 . . . cord-004775-foaf3vyl 121 1 The the DT cord-004775-foaf3vyl 121 2 preferential preferential JJ cord-004775-foaf3vyl 121 3 recognition recognition NN cord-004775-foaf3vyl 121 4 of of IN cord-004775-foaf3vyl 121 5 the the DT cord-004775-foaf3vyl 121 6 20 20 CD cord-004775-foaf3vyl 121 7 kD kd NN cord-004775-foaf3vyl 121 8 nueleocapsid nueleocapsid NN cord-004775-foaf3vyl 121 9 protein protein NN cord-004775-foaf3vyl 121 10 of of IN cord-004775-foaf3vyl 121 11 BEV BEV NNP cord-004775-foaf3vyl 121 12 by by IN cord-004775-foaf3vyl 121 13 heterologous heterologous NNP cord-004775-foaf3vyl 121 14 cattle cattle NNS cord-004775-foaf3vyl 121 15 sera sera NNP cord-004775-foaf3vyl 121 16 mentioned mention VBN cord-004775-foaf3vyl 121 17 above above RB cord-004775-foaf3vyl 121 18 may may MD cord-004775-foaf3vyl 121 19 indicate indicate VB cord-004775-foaf3vyl 121 20 a a DT cord-004775-foaf3vyl 121 21 broadly broadly RB cord-004775-foaf3vyl 121 22 reacting react VBG cord-004775-foaf3vyl 121 23 group group NN cord-004775-foaf3vyl 121 24 specitic specitic NNP cord-004775-foaf3vyl 121 25 antigen antigen NN cord-004775-foaf3vyl 121 26 . . . cord-004775-foaf3vyl 122 1 A a DT cord-004775-foaf3vyl 122 2 positive positive JJ cord-004775-foaf3vyl 122 3 IF if NN cord-004775-foaf3vyl 122 4 was be VBD cord-004775-foaf3vyl 122 5 noted note VBN cord-004775-foaf3vyl 122 6 with with IN cord-004775-foaf3vyl 122 7 Lyon Lyon NNP cord-004775-foaf3vyl 122 8 4 4 CD cord-004775-foaf3vyl 122 9 virus virus NN cord-004775-foaf3vyl 122 10 and and CC cord-004775-foaf3vyl 122 11 BEV BEV NNP cord-004775-foaf3vyl 122 12 antibodies antibody NNS cord-004775-foaf3vyl 122 13 in in IN cord-004775-foaf3vyl 122 14 horse horse NN cord-004775-foaf3vyl 122 15 sera sera NNP cord-004775-foaf3vyl 122 16 , , , cord-004775-foaf3vyl 122 17 and and CC cord-004775-foaf3vyl 122 18 antisera antisera NNP cord-004775-foaf3vyl 122 19 t?om t?om XX cord-004775-foaf3vyl 123 1 cattle cattle NNS cord-004775-foaf3vyl 123 2 positive positive JJ cord-004775-foaf3vyl 123 3 for for IN cord-004775-foaf3vyl 123 4 Lyon Lyon NNP cord-004775-foaf3vyl 123 5 4 4 CD cord-004775-foaf3vyl 123 6 reacted react VBD cord-004775-foaf3vyl 123 7 in in IN cord-004775-foaf3vyl 123 8 seroneutralization seroneutralization NN cord-004775-foaf3vyl 123 9 , , , cord-004775-foaf3vyl 123 10 ELISA ELISA NNP cord-004775-foaf3vyl 123 11 and and CC cord-004775-foaf3vyl 123 12 RIP RIP NNP cord-004775-foaf3vyl 123 13 with with IN cord-004775-foaf3vyl 123 14 BEV BEV NNP cord-004775-foaf3vyl 123 15 ( ( -LRB- cord-004775-foaf3vyl 123 16 2 2 CD cord-004775-foaf3vyl 123 17 , , , cord-004775-foaf3vyl 123 18 14 14 CD cord-004775-foaf3vyl 123 19 ) ) -RRB- cord-004775-foaf3vyl 123 20 . . . cord-004775-foaf3vyl 124 1 Evidence evidence NN cord-004775-foaf3vyl 124 2 of of IN cord-004775-foaf3vyl 124 3 a a DT cord-004775-foaf3vyl 124 4 reaction reaction NN cord-004775-foaf3vyl 124 5 of of IN cord-004775-foaf3vyl 124 6 the the DT cord-004775-foaf3vyl 124 7 particles particle NNS cord-004775-foaf3vyl 124 8 in in IN cord-004775-foaf3vyl 124 9 human human JJ cord-004775-foaf3vyl 124 10 feces fece NNS cord-004775-foaf3vyl 124 11 with with IN cord-004775-foaf3vyl 124 12 sera sera NNP cord-004775-foaf3vyl 124 13 containing contain VBG cord-004775-foaf3vyl 124 14 antibodies antibody NNS cord-004775-foaf3vyl 124 15 against against IN cord-004775-foaf3vyl 124 16 BRV BRV NNP cord-004775-foaf3vyl 124 17 and and CC cord-004775-foaf3vyl 124 18 BEV BEV NNP cord-004775-foaf3vyl 124 19 , , , cord-004775-foaf3vyl 124 20 respectively respectively RB cord-004775-foaf3vyl 124 21 , , , cord-004775-foaf3vyl 124 22 were be VBD cord-004775-foaf3vyl 124 23 obtained obtain VBN cord-004775-foaf3vyl 124 24 in in IN cord-004775-foaf3vyl 124 25 IEM IEM NNP cord-004775-foaf3vyl 124 26 ( ( -LRB- cord-004775-foaf3vyl 124 27 8) 8) NNP cord-004775-foaf3vyl 124 28 , , , cord-004775-foaf3vyl 124 29 ( ( -LRB- cord-004775-foaf3vyl 124 30 Flewett Flewett NNP cord-004775-foaf3vyl 124 31 personal personal JJ cord-004775-foaf3vyl 124 32 communication communication NN cord-004775-foaf3vyl 124 33 ) ) -RRB- cord-004775-foaf3vyl 124 34 . . . cord-004775-foaf3vyl 125 1 Further further JJ cord-004775-foaf3vyl 125 2 tests test NNS cord-004775-foaf3vyl 125 3 , , , cord-004775-foaf3vyl 125 4 however however RB cord-004775-foaf3vyl 125 5 , , , cord-004775-foaf3vyl 125 6 are be VBP cord-004775-foaf3vyl 125 7 needed need VBN cord-004775-foaf3vyl 125 8 to to TO cord-004775-foaf3vyl 125 9 confirm confirm VB cord-004775-foaf3vyl 125 10 the the DT cord-004775-foaf3vyl 125 11 antigenie antigenie JJ cord-004775-foaf3vyl 125 12 relatedness relatedness NN cord-004775-foaf3vyl 125 13 of of IN cord-004775-foaf3vyl 125 14 the the DT cord-004775-foaf3vyl 125 15 putative putative JJ cord-004775-foaf3vyl 125 16 human human JJ cord-004775-foaf3vyl 125 17 torovirus torovirus NN cord-004775-foaf3vyl 125 18 with with IN cord-004775-foaf3vyl 125 19 Bt Bt NNP cord-004775-foaf3vyl 125 20 ~ ~ NNP cord-004775-foaf3vyl 125 21 V V NNP cord-004775-foaf3vyl 125 22 and and CC cord-004775-foaf3vyl 125 23 BEV BEV NNP cord-004775-foaf3vyl 125 24 . . . cord-004775-foaf3vyl 126 1 For for IN cord-004775-foaf3vyl 126 2 BEV BEV NNP cord-004775-foaf3vyl 126 3 a a DT cord-004775-foaf3vyl 126 4 purification purification NN cord-004775-foaf3vyl 126 5 procedure procedure NN cord-004775-foaf3vyl 126 6 was be VBD cord-004775-foaf3vyl 126 7 developed develop VBN cord-004775-foaf3vyl 126 8 ( ( -LRB- cord-004775-foaf3vyl 126 9 2 2 CD cord-004775-foaf3vyl 126 10 ) ) -RRB- cord-004775-foaf3vyl 126 11 . . . cord-004775-foaf3vyl 127 1 Supernatants supernatant NNS cord-004775-foaf3vyl 127 2 from from IN cord-004775-foaf3vyl 127 3 infected infected JJ cord-004775-foaf3vyl 127 4 tissue tissue NN cord-004775-foaf3vyl 127 5 cultures culture NNS cord-004775-foaf3vyl 127 6 were be VBD cord-004775-foaf3vyl 127 7 mixed mix VBN cord-004775-foaf3vyl 127 8 with with IN cord-004775-foaf3vyl 127 9 ammonium ammonium NN cord-004775-foaf3vyl 127 10 sulphate sulphate NN cord-004775-foaf3vyl 127 11 ( ( -LRB- cord-004775-foaf3vyl 127 12 end end NN cord-004775-foaf3vyl 127 13 concentration concentration NN cord-004775-foaf3vyl 127 14 25 25 CD cord-004775-foaf3vyl 127 15 to to TO cord-004775-foaf3vyl 127 16 50 50 CD cord-004775-foaf3vyl 127 17 per per IN cord-004775-foaf3vyl 127 18 cent cent NN cord-004775-foaf3vyl 127 19 ) ) -RRB- cord-004775-foaf3vyl 127 20 and and CC cord-004775-foaf3vyl 127 21 the the DT cord-004775-foaf3vyl 127 22 resuspended resuspended JJ cord-004775-foaf3vyl 127 23 and and CC cord-004775-foaf3vyl 127 24 clarified clarify VBN cord-004775-foaf3vyl 127 25 precipitate precipitate NN cord-004775-foaf3vyl 127 26 was be VBD cord-004775-foaf3vyl 127 27 layered layer VBN cord-004775-foaf3vyl 127 28 on on IN cord-004775-foaf3vyl 127 29 top top NN cord-004775-foaf3vyl 127 30 of of IN cord-004775-foaf3vyl 127 31 a a DT cord-004775-foaf3vyl 127 32 linear linear JJ cord-004775-foaf3vyl 127 33 15 15 CD cord-004775-foaf3vyl 127 34 to to TO cord-004775-foaf3vyl 127 35 50 50 CD cord-004775-foaf3vyl 127 36 per per IN cord-004775-foaf3vyl 127 37 cent cent NN cord-004775-foaf3vyl 128 1 ( ( -LRB- cord-004775-foaf3vyl 128 2 w w NNP cord-004775-foaf3vyl 128 3 / / SYM cord-004775-foaf3vyl 128 4 w w NN cord-004775-foaf3vyl 128 5 ) ) -RRB- cord-004775-foaf3vyl 128 6 sucrose sucrose NN cord-004775-foaf3vyl 128 7 gradient gradient NN cord-004775-foaf3vyl 128 8 , , , cord-004775-foaf3vyl 128 9 . . . cord-004775-foaf3vyl 129 1 After after IN cord-004775-foaf3vyl 129 2 centrifugation centrifugation NN cord-004775-foaf3vyl 129 3 to to IN cord-004775-foaf3vyl 129 4 equilibrium equilibrium NN cord-004775-foaf3vyl 129 5 and and CC cord-004775-foaf3vyl 129 6 fractionation fractionation NN cord-004775-foaf3vyl 129 7 , , , cord-004775-foaf3vyl 129 8 the the DT cord-004775-foaf3vyl 129 9 samples sample NNS cord-004775-foaf3vyl 129 10 were be VBD cord-004775-foaf3vyl 129 11 monitored monitor VBN cord-004775-foaf3vyl 129 12 for for IN cord-004775-foaf3vyl 129 13 the the DT cord-004775-foaf3vyl 129 14 presence presence NN cord-004775-foaf3vyl 129 15 of of IN cord-004775-foaf3vyl 129 16 virus virus NN cord-004775-foaf3vyl 129 17 antigen antigen NN cord-004775-foaf3vyl 129 18 by by IN cord-004775-foaf3vyl 129 19 indirect indirect JJ cord-004775-foaf3vyl 129 20 ELISA ELISA NNP cord-004775-foaf3vyl 129 21 . . . cord-004775-foaf3vyl 130 1 For for IN cord-004775-foaf3vyl 130 2 some some DT cord-004775-foaf3vyl 130 3 experiments experiment NNS cord-004775-foaf3vyl 130 4 , , , cord-004775-foaf3vyl 130 5 e.g. e.g. RB cord-004775-foaf3vyl 130 6 preparation preparation NN cord-004775-foaf3vyl 130 7 of of IN cord-004775-foaf3vyl 130 8 ELISA ELISA NNP cord-004775-foaf3vyl 130 9 antigen antigen NN cord-004775-foaf3vyl 130 10 ibr ibr JJ cord-004775-foaf3vyl 130 11 serology serology NN cord-004775-foaf3vyl 130 12 , , , cord-004775-foaf3vyl 130 13 a a DT cord-004775-foaf3vyl 130 14 lower low JJR cord-004775-foaf3vyl 130 15 degree degree NN cord-004775-foaf3vyl 130 16 of of IN cord-004775-foaf3vyl 130 17 purity purity NN cord-004775-foaf3vyl 130 18 was be VBD cord-004775-foaf3vyl 130 19 sufficient sufficient JJ cord-004775-foaf3vyl 130 20 . . . cord-004775-foaf3vyl 131 1 In in IN cord-004775-foaf3vyl 131 2 this this DT cord-004775-foaf3vyl 131 3 case case NN cord-004775-foaf3vyl 131 4 the the DT cord-004775-foaf3vyl 131 5 precipitated precipitated JJ cord-004775-foaf3vyl 131 6 and and CC cord-004775-foaf3vyl 131 7 resuspended resuspended JJ cord-004775-foaf3vyl 131 8 material material NN cord-004775-foaf3vyl 131 9 was be VBD cord-004775-foaf3vyl 131 10 sedimented sediment VBN cord-004775-foaf3vyl 131 11 through through IN cord-004775-foaf3vyl 131 12 a a DT cord-004775-foaf3vyl 131 13 15 15 CD cord-004775-foaf3vyl 131 14 per per IN cord-004775-foaf3vyl 131 15 cent cent NN cord-004775-foaf3vyl 131 16 sucrose sucrose NN cord-004775-foaf3vyl 131 17 layer layer NN cord-004775-foaf3vyl 131 18 onto onto IN cord-004775-foaf3vyl 131 19 a a DT cord-004775-foaf3vyl 131 20 50 50 CD cord-004775-foaf3vyl 131 21 per per IN cord-004775-foaf3vyl 131 22 cent cent NN cord-004775-foaf3vyl 131 23 sucrose sucrose NN cord-004775-foaf3vyl 131 24 cushion cushion NN cord-004775-foaf3vyl 131 25 . . . cord-004775-foaf3vyl 132 1 BRV BRV NNP cord-004775-foaf3vyl 132 2 was be VBD cord-004775-foaf3vyl 132 3 purified purify VBN cord-004775-foaf3vyl 132 4 from from IN cord-004775-foaf3vyl 132 5 diarrheic diarrheic NNS cord-004775-foaf3vyl 132 6 feces fece NNS cord-004775-foaf3vyl 132 7 ( ( -LRB- cord-004775-foaf3vyl 132 8 1 1 CD cord-004775-foaf3vyl 132 9 , , , cord-004775-foaf3vyl 132 10 17 17 CD cord-004775-foaf3vyl 132 11 ) ) -RRB- cord-004775-foaf3vyl 132 12 . . . cord-004775-foaf3vyl 133 1 Fecal fecal JJ cord-004775-foaf3vyl 133 2 material material NN cord-004775-foaf3vyl 133 3 was be VBD cord-004775-foaf3vyl 133 4 diluted dilute VBN cord-004775-foaf3vyl 133 5 1:2 1:2 CD cord-004775-foaf3vyl 133 6 to to IN cord-004775-foaf3vyl 133 7 1:4 1:4 CD cord-004775-foaf3vyl 133 8 and and CC cord-004775-foaf3vyl 133 9 clarified clarify VBN cord-004775-foaf3vyl 133 10 by by IN cord-004775-foaf3vyl 133 11 low low JJ cord-004775-foaf3vyl 133 12 speed speed NN cord-004775-foaf3vyl 133 13 centrifugation centrifugation NN cord-004775-foaf3vyl 133 14 . . . cord-004775-foaf3vyl 134 1 Depending depend VBG cord-004775-foaf3vyl 134 2 on on IN cord-004775-foaf3vyl 134 3 the the DT cord-004775-foaf3vyl 134 4 degree degree NN cord-004775-foaf3vyl 134 5 of of IN cord-004775-foaf3vyl 134 6 purity purity NN cord-004775-foaf3vyl 134 7 desired desire VBN cord-004775-foaf3vyl 134 8 , , , cord-004775-foaf3vyl 134 9 the the DT cord-004775-foaf3vyl 134 10 supernatant supernatant NN cord-004775-foaf3vyl 134 11 was be VBD cord-004775-foaf3vyl 134 12 either either CC cord-004775-foaf3vyl 134 13 used use VBN cord-004775-foaf3vyl 134 14 directly directly RB cord-004775-foaf3vyl 134 15 , , , cord-004775-foaf3vyl 134 16 pelleted pellete VBN cord-004775-foaf3vyl 134 17 at at IN cord-004775-foaf3vyl 134 18 80,000 80,000 CD cord-004775-foaf3vyl 134 19 to to TO cord-004775-foaf3vyl 134 20 100,000 100,000 CD cord-004775-foaf3vyl 134 21 × × NN cord-004775-foaf3vyl 134 22 g g NN cord-004775-foaf3vyl 134 23 ; ; : cord-004775-foaf3vyl 134 24 or or CC cord-004775-foaf3vyl 134 25 further further RB cord-004775-foaf3vyl 134 26 purified purify VBN cord-004775-foaf3vyl 134 27 by by IN cord-004775-foaf3vyl 134 28 the the DT cord-004775-foaf3vyl 134 29 methods method NNS cord-004775-foaf3vyl 134 30 described describe VBN cord-004775-foaf3vyl 134 31 for for IN cord-004775-foaf3vyl 134 32 BEV BEV NNP cord-004775-foaf3vyl 134 33 . . . cord-004775-foaf3vyl 135 1 In in IN cord-004775-foaf3vyl 135 2 BEV BEV NNP cord-004775-foaf3vyl 135 3 infected infect VBD cord-004775-foaf3vyl 135 4 E. E. NNP cord-004775-foaf3vyl 135 5 derm derm NNP cord-004775-foaf3vyl 135 6 cells cell NNS cord-004775-foaf3vyl 136 1 an an DT cord-004775-foaf3vyl 136 2 increase increase NN cord-004775-foaf3vyl 136 3 in in IN cord-004775-foaf3vyl 136 4 extracellular extracellular JJ cord-004775-foaf3vyl 136 5 infectivity infectivity NN cord-004775-foaf3vyl 136 6 was be VBD cord-004775-foaf3vyl 136 7 noted note VBN cord-004775-foaf3vyl 136 8 between between IN cord-004775-foaf3vyl 136 9 the the DT cord-004775-foaf3vyl 136 10 8th 8th JJ cord-004775-foaf3vyl 136 11 and and CC cord-004775-foaf3vyl 136 12 9th 9th JJ cord-004775-foaf3vyl 136 13 hour hour NN cord-004775-foaf3vyl 136 14 after after IN cord-004775-foaf3vyl 136 15 infection infection NN cord-004775-foaf3vyl 136 16 , , , cord-004775-foaf3vyl 136 17 and and CC cord-004775-foaf3vyl 136 18 a a DT cord-004775-foaf3vyl 136 19 plateau plateau NN cord-004775-foaf3vyl 136 20 was be VBD cord-004775-foaf3vyl 136 21 reached reach VBN cord-004775-foaf3vyl 136 22 at at IN cord-004775-foaf3vyl 136 23 about about RB cord-004775-foaf3vyl 136 24 15 15 CD cord-004775-foaf3vyl 136 25 hours hour NNS cord-004775-foaf3vyl 136 26 . . . cord-004775-foaf3vyl 137 1 A a DT cord-004775-foaf3vyl 137 2 pronounced pronounce VBN cord-004775-foaf3vyl 137 3 cytepathic cytepathic JJ cord-004775-foaf3vyl 137 4 effect effect NN cord-004775-foaf3vyl 137 5 ( ( -LRB- cord-004775-foaf3vyl 137 6 CPE CPE NNP cord-004775-foaf3vyl 137 7 ) ) -RRB- cord-004775-foaf3vyl 137 8 was be VBD cord-004775-foaf3vyl 137 9 evident evident JJ cord-004775-foaf3vyl 137 10 about about IN cord-004775-foaf3vyl 137 11 21 21 CD cord-004775-foaf3vyl 137 12 hours hour NNS cord-004775-foaf3vyl 137 13 post post NN cord-004775-foaf3vyl 137 14 infection infection NN cord-004775-foaf3vyl 137 15 . . . cord-004775-foaf3vyl 138 1 In in IN cord-004775-foaf3vyl 138 2 the the DT cord-004775-foaf3vyl 138 3 presence presence NN cord-004775-foaf3vyl 138 4 of of IN cord-004775-foaf3vyl 138 5 actinomycin actinomycin NNS cord-004775-foaf3vyl 138 6 D D NNP cord-004775-foaf3vyl 138 7 and and CC cord-004775-foaf3vyl 138 8 a a DT cord-004775-foaf3vyl 138 9 - - HYPH cord-004775-foaf3vyl 138 10 amanitin amanitin NNP cord-004775-foaf3vyl 138 11 , , , cord-004775-foaf3vyl 138 12 BEV BEV NNP cord-004775-foaf3vyl 138 13 replication replication NN cord-004775-foaf3vyl 138 14 was be VBD cord-004775-foaf3vyl 138 15 drastically drastically RB cord-004775-foaf3vyl 138 16 decreased decrease VBN cord-004775-foaf3vyl 138 17 when when WRB cord-004775-foaf3vyl 138 18 the the DT cord-004775-foaf3vyl 138 19 drugs drug NNS cord-004775-foaf3vyl 138 20 were be VBD cord-004775-foaf3vyl 138 21 added add VBN cord-004775-foaf3vyl 138 22 during during IN cord-004775-foaf3vyl 138 23 the the DT cord-004775-foaf3vyl 138 24 first first JJ cord-004775-foaf3vyl 138 25 8 8 CD cord-004775-foaf3vyl 138 26 hours hour NNS cord-004775-foaf3vyl 138 27 after after IN cord-004775-foaf3vyl 138 28 infection infection NN cord-004775-foaf3vyl 138 29 . . . cord-004775-foaf3vyl 139 1 UW UW NNP cord-004775-foaf3vyl 139 2 preirradiation preirradiation NN cord-004775-foaf3vyl 139 3 of of IN cord-004775-foaf3vyl 139 4 the the DT cord-004775-foaf3vyl 139 5 cells cell NNS cord-004775-foaf3vyl 139 6 also also RB cord-004775-foaf3vyl 139 7 interfered interfere VBD cord-004775-foaf3vyl 139 8 with with IN cord-004775-foaf3vyl 139 9 BEV BEV NNP cord-004775-foaf3vyl 139 10 multiplication multiplication NN cord-004775-foaf3vyl 139 11 . . . cord-004775-foaf3vyl 140 1 From from IN cord-004775-foaf3vyl 140 2 these these DT cord-004775-foaf3vyl 140 3 results result NNS cord-004775-foaf3vyl 140 4 it -PRON- PRP cord-004775-foaf3vyl 140 5 appears appear VBZ cord-004775-foaf3vyl 140 6 that that IN cord-004775-foaf3vyl 140 7 BEV BEV NNP cord-004775-foaf3vyl 140 8 replication replication NN cord-004775-foaf3vyl 140 9 depends depend VBZ cord-004775-foaf3vyl 140 10 on on IN cord-004775-foaf3vyl 140 11 some some DT cord-004775-foaf3vyl 140 12 nuclear nuclear JJ cord-004775-foaf3vyl 140 13 function function NN cord-004775-foaf3vyl 140 14 of of IN cord-004775-foaf3vyl 140 15 the the DT cord-004775-foaf3vyl 140 16 host host NN cord-004775-foaf3vyl 140 17 cell cell NN cord-004775-foaf3vyl 140 18 ( ( -LRB- cord-004775-foaf3vyl 140 19 13 13 CD cord-004775-foaf3vyl 140 20 ) ) -RRB- cord-004775-foaf3vyl 140 21 . . . cord-004775-foaf3vyl 141 1 ( ( -LRB- cord-004775-foaf3vyl 141 2 Fig Fig NNP cord-004775-foaf3vyl 141 3 . . . cord-004775-foaf3vyl 141 4 6 6 CD cord-004775-foaf3vyl 141 5 ) ) -RRB- cord-004775-foaf3vyl 141 6 . . . cord-004775-foaf3vyl 142 1 In in IN cord-004775-foaf3vyl 142 2 infected infected JJ cord-004775-foaf3vyl 142 3 E. E. NNP cord-004775-foaf3vyl 142 4 derm derm NNP cord-004775-foaf3vyl 142 5 cells cell NNS cord-004775-foaf3vyl 142 6 BEV BEV NNP cord-004775-foaf3vyl 142 7 is be VBZ cord-004775-foaf3vyl 142 8 assembled assemble VBN cord-004775-foaf3vyl 142 9 by by IN cord-004775-foaf3vyl 142 10 budding bud VBG cord-004775-foaf3vyl 142 11 of of IN cord-004775-foaf3vyl 142 12 a a DT cord-004775-foaf3vyl 142 13 preformed preformed JJ cord-004775-foaf3vyl 142 14 rigid rigid JJ cord-004775-foaf3vyl 142 15 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 142 16 through through IN cord-004775-foaf3vyl 142 17 intracytoptasmic intracytoptasmic NNP cord-004775-foaf3vyl 142 18 membranes membrane NNS cord-004775-foaf3vyl 142 19 ( ( -LRB- cord-004775-foaf3vyl 142 20 9 9 CD cord-004775-foaf3vyl 142 21 ) ) -RRB- cord-004775-foaf3vyl 142 22 . . . cord-004775-foaf3vyl 143 1 Tubular tubular JJ cord-004775-foaf3vyl 143 2 structures structure NNS cord-004775-foaf3vyl 143 3 , , , cord-004775-foaf3vyl 143 4 representing represent VBG cord-004775-foaf3vyl 143 5 nucleocapsids nucleocapsid NNS cord-004775-foaf3vyl 143 6 , , , cord-004775-foaf3vyl 143 7 are be VBP cord-004775-foaf3vyl 143 8 formed form VBN cord-004775-foaf3vyl 143 9 in in IN cord-004775-foaf3vyl 143 10 places place NNS cord-004775-foaf3vyl 143 11 distant distant JJ cord-004775-foaf3vyl 143 12 from from IN cord-004775-foaf3vyl 143 13 the the DT cord-004775-foaf3vyl 143 14 budding bud VBG cord-004775-foaf3vyl 143 15 site site NN cord-004775-foaf3vyl 143 16 . . . cord-004775-foaf3vyl 144 1 They -PRON- PRP cord-004775-foaf3vyl 144 2 are be VBP cord-004775-foaf3vyl 144 3 often often RB cord-004775-foaf3vyl 144 4 seen see VBN cord-004775-foaf3vyl 144 5 in in IN cord-004775-foaf3vyl 144 6 immediate immediate JJ cord-004775-foaf3vyl 144 7 proximity proximity NN cord-004775-foaf3vyl 144 8 of of IN cord-004775-foaf3vyl 144 9 cytoplasmic cytoplasmic JJ cord-004775-foaf3vyl 144 10 accumulations accumulation NNS cord-004775-foaf3vyl 144 11 of of IN cord-004775-foaf3vyl 144 12 an an DT cord-004775-foaf3vyl 144 13 electron electron NN cord-004775-foaf3vyl 144 14 dense dense JJ cord-004775-foaf3vyl 144 15 granular granular JJ cord-004775-foaf3vyl 144 16 substance substance NN cord-004775-foaf3vyl 144 17 supposed suppose VBN cord-004775-foaf3vyl 144 18 to to TO cord-004775-foaf3vyl 144 19 consist consist VB cord-004775-foaf3vyl 144 20 of of IN cord-004775-foaf3vyl 144 21 ~iral ~iral NNP cord-004775-foaf3vyl 144 22 material material NN cord-004775-foaf3vyl 144 23 . . . cord-004775-foaf3vyl 145 1 Tubules tubule NNS cord-004775-foaf3vyl 145 2 were be VBD cord-004775-foaf3vyl 145 3 not not RB cord-004775-foaf3vyl 145 4 only only RB cord-004775-foaf3vyl 145 5 encountered encounter VBN cord-004775-foaf3vyl 145 6 in in IN cord-004775-foaf3vyl 145 7 the the DT cord-004775-foaf3vyl 145 8 cytoplasm cytoplasm NN cord-004775-foaf3vyl 145 9 but but CC cord-004775-foaf3vyl 145 10 Budding budding NN cord-004775-foaf3vyl 145 11 of of IN cord-004775-foaf3vyl 145 12 virus virus NN cord-004775-foaf3vyl 145 13 particles particle NNS cord-004775-foaf3vyl 145 14 occurs occur VBZ cord-004775-foaf3vyl 145 15 predominantly predominantly RB cord-004775-foaf3vyl 145 16 into into IN cord-004775-foaf3vyl 145 17 the the DT cord-004775-foaf3vyl 145 18 Golgi Golgi NNP cord-004775-foaf3vyl 145 19 system system NN cord-004775-foaf3vyl 145 20 but but CC cord-004775-foaf3vyl 145 21 was be VBD cord-004775-foaf3vyl 145 22 also also RB cord-004775-foaf3vyl 145 23 observed observe VBN cord-004775-foaf3vyl 145 24 through through IN cord-004775-foaf3vyl 145 25 membranes membrane NNS cord-004775-foaf3vyl 145 26 of of IN cord-004775-foaf3vyl 145 27 the the DT cord-004775-foaf3vyl 145 28 rough rough JJ cord-004775-foaf3vyl 145 29 endoplasmic endoplasmic NN cord-004775-foaf3vyl 145 30 reticulum reticulum NN cord-004775-foaf3vyl 145 31 and and CC cord-004775-foaf3vyl 145 32 into into IN cord-004775-foaf3vyl 145 33 the the DT cord-004775-foaf3vyl 145 34 perinuclear perinuclear NNP cord-004775-foaf3vyl 145 35 space space NN cord-004775-foaf3vyl 145 36 . . . cord-004775-foaf3vyl 146 1 The the DT cord-004775-foaf3vyl 146 2 following following JJ cord-004775-foaf3vyl 146 3 sequence sequence NN cord-004775-foaf3vyl 146 4 of of IN cord-004775-foaf3vyl 146 5 events event NNS cord-004775-foaf3vyl 146 6 was be VBD cord-004775-foaf3vyl 146 7 reconstructed reconstruct VBN cord-004775-foaf3vyl 146 8 : : : cord-004775-foaf3vyl 146 9 The the DT cord-004775-foaf3vyl 146 10 intracytoplasmic intracytoplasmic JJ cord-004775-foaf3vyl 146 11 nucleoeapsid nucleoeapsid NN cord-004775-foaf3vyl 146 12 becomes become VBZ cord-004775-foaf3vyl 146 13 attached attach VBN cord-004775-foaf3vyl 146 14 to to IN cord-004775-foaf3vyl 146 15 the the DT cord-004775-foaf3vyl 146 16 membrane membrane NN cord-004775-foaf3vyl 146 17 with with IN cord-004775-foaf3vyl 146 18 one one CD cord-004775-foaf3vyl 146 19 of of IN cord-004775-foaf3vyl 146 20 its -PRON- PRP$ cord-004775-foaf3vyl 146 21 rounded rounded JJ cord-004775-foaf3vyl 146 22 ends end NNS cord-004775-foaf3vyl 146 23 and and CC cord-004775-foaf3vyl 146 24 subsequently subsequently RB cord-004775-foaf3vyl 146 25 sideways sideways RB cord-004775-foaf3vyl 146 26 . . . cord-004775-foaf3vyl 147 1 During during IN cord-004775-foaf3vyl 147 2 budding bud VBG cord-004775-foaf3vyl 147 3 the the DT cord-004775-foaf3vyl 147 4 eapsid eapsid NN cord-004775-foaf3vyl 147 5 apparently apparently RB cord-004775-foaf3vyl 147 6 acquires acquire VBZ cord-004775-foaf3vyl 147 7 its -PRON- PRP$ cord-004775-foaf3vyl 147 8 definite definite JJ cord-004775-foaf3vyl 147 9 diameter diameter NN cord-004775-foaf3vyl 147 10 and and CC cord-004775-foaf3vyl 147 11 electron electron NN cord-004775-foaf3vyl 147 12 density density NN cord-004775-foaf3vyl 147 13 . . . cord-004775-foaf3vyl 148 1 As as IN cord-004775-foaf3vyl 148 2 a a DT cord-004775-foaf3vyl 148 3 result result NN cord-004775-foaf3vyl 148 4 of of IN cord-004775-foaf3vyl 148 5 the the DT cord-004775-foaf3vyl 148 6 budding budding NN cord-004775-foaf3vyl 148 7 process process NN cord-004775-foaf3vyl 148 8 an an DT cord-004775-foaf3vyl 148 9 enveloped envelop VBN cord-004775-foaf3vyl 148 10 bacilliform bacilliform NNP cord-004775-foaf3vyl 148 11 virus virus NN cord-004775-foaf3vyl 148 12 particle particle NN cord-004775-foaf3vyl 148 13 is be VBZ cord-004775-foaf3vyl 148 14 found find VBN cord-004775-foaf3vyl 148 15 free free JJ cord-004775-foaf3vyl 148 16 in in IN cord-004775-foaf3vyl 148 17 the the DT cord-004775-foaf3vyl 148 18 lumen lumen NN cord-004775-foaf3vyl 148 19 of of IN cord-004775-foaf3vyl 148 20 the the DT cord-004775-foaf3vyl 148 21 cytoplasmic cytoplasmic JJ cord-004775-foaf3vyl 148 22 cisternae cisternae NN cord-004775-foaf3vyl 148 23 ( ( -LRB- cord-004775-foaf3vyl 148 24 Fig Fig NNP cord-004775-foaf3vyl 148 25 . . NNP cord-004775-foaf3vyl 148 26 7 7 CD cord-004775-foaf3vyl 148 27 ) ) -RRB- cord-004775-foaf3vyl 148 28 . . . cord-004775-foaf3vyl 149 1 Virus virus NN cord-004775-foaf3vyl 149 2 containing contain VBG cord-004775-foaf3vyl 149 3 vesicles vesicle NNS cord-004775-foaf3vyl 149 4 merge merge VBP cord-004775-foaf3vyl 149 5 with with IN cord-004775-foaf3vyl 149 6 the the DT cord-004775-foaf3vyl 149 7 peripheral peripheral JJ cord-004775-foaf3vyl 149 8 plasma plasma NN cord-004775-foaf3vyl 149 9 membrane membrane NN cord-004775-foaf3vyl 149 10 and and CC cord-004775-foaf3vyl 149 11 release release VB cord-004775-foaf3vyl 149 12 their -PRON- PRP$ cord-004775-foaf3vyl 149 13 contents content NNS cord-004775-foaf3vyl 149 14 . . . cord-004775-foaf3vyl 150 1 During during IN cord-004775-foaf3vyl 150 2 transition transition NN cord-004775-foaf3vyl 150 3 from from IN cord-004775-foaf3vyl 150 4 the the DT cord-004775-foaf3vyl 150 5 intravesieular intravesieular NNP cord-004775-foaf3vyl 150 6 to to IN cord-004775-foaf3vyl 150 7 the the DT cord-004775-foaf3vyl 150 8 extracellular extracellular JJ cord-004775-foaf3vyl 150 9 state state NN cord-004775-foaf3vyl 150 10 the the DT cord-004775-foaf3vyl 150 11 morphology morphology NN cord-004775-foaf3vyl 150 12 of of IN cord-004775-foaf3vyl 150 13 virus virus NN cord-004775-foaf3vyl 150 14 particles particle NNS cord-004775-foaf3vyl 150 15 changes change NNS cord-004775-foaf3vyl 150 16 from from IN cord-004775-foaf3vyl 150 17 the the DT cord-004775-foaf3vyl 150 18 rod rod NN cord-004775-foaf3vyl 150 19 - - HYPH cord-004775-foaf3vyl 150 20 like like JJ cord-004775-foaf3vyl 150 21 form form NN cord-004775-foaf3vyl 150 22 to to IN cord-004775-foaf3vyl 150 23 the the DT cord-004775-foaf3vyl 150 24 characteristic characteristic JJ cord-004775-foaf3vyl 150 25 torus torus NN cord-004775-foaf3vyl 150 26 form form NN cord-004775-foaf3vyl 150 27 ( ( -LRB- cord-004775-foaf3vyl 150 28 Fig Fig NNP cord-004775-foaf3vyl 150 29 . . . cord-004775-foaf3vyl 150 30 8) 8) NNP cord-004775-foaf3vyl 150 31 . . . cord-004775-foaf3vyl 151 1 B b NN cord-004775-foaf3vyl 151 2 R r NN cord-004775-foaf3vyl 151 3 V v NN cord-004775-foaf3vyl 151 4 morphogenesis morphogenesis NN cord-004775-foaf3vyl 151 5 can can MD cord-004775-foaf3vyl 151 6 not not RB cord-004775-foaf3vyl 151 7 be be VB cord-004775-foaf3vyl 151 8 followed follow VBN cord-004775-foaf3vyl 151 9 sequentially sequentially RB cord-004775-foaf3vyl 151 10 since since IN cord-004775-foaf3vyl 151 11 virus virus NN cord-004775-foaf3vyl 151 12 propagation propagation NN cord-004775-foaf3vyl 151 13 has have VBZ cord-004775-foaf3vyl 151 14 so so RB cord-004775-foaf3vyl 151 15 far far RB cord-004775-foaf3vyl 151 16 not not RB cord-004775-foaf3vyl 151 17 been be VBN cord-004775-foaf3vyl 151 18 achieved achieve VBN cord-004775-foaf3vyl 151 19 in in IN cord-004775-foaf3vyl 151 20 tissue tissue NN cord-004775-foaf3vyl 151 21 culture culture NN cord-004775-foaf3vyl 151 22 . . . cord-004775-foaf3vyl 152 1 The the DT cord-004775-foaf3vyl 152 2 available available JJ cord-004775-foaf3vyl 152 3 data datum NNS cord-004775-foaf3vyl 152 4 , , , cord-004775-foaf3vyl 152 5 however however RB cord-004775-foaf3vyl 152 6 ( ( -LRB- cord-004775-foaf3vyl 152 7 12 12 CD cord-004775-foaf3vyl 152 8 ) ) -RRB- cord-004775-foaf3vyl 152 9 , , , cord-004775-foaf3vyl 152 10 indicate indicate VBP cord-004775-foaf3vyl 152 11 that that IN cord-004775-foaf3vyl 152 12 the the DT cord-004775-foaf3vyl 152 13 BRV BRV NNP cord-004775-foaf3vyl 152 14 morphopoiesis morphopoiesis NN cord-004775-foaf3vyl 152 15 is be VBZ cord-004775-foaf3vyl 152 16 similar similar JJ cord-004775-foaf3vyl 152 17 to to IN cord-004775-foaf3vyl 152 18 that that DT cord-004775-foaf3vyl 152 19 of of IN cord-004775-foaf3vyl 152 20 BEV BEV NNP cord-004775-foaf3vyl 152 21 . . . cord-004775-foaf3vyl 153 1 Tubular tubular JJ cord-004775-foaf3vyl 153 2 structures structure NNS cord-004775-foaf3vyl 153 3 were be VBD cord-004775-foaf3vyl 153 4 encountered encounter VBN cord-004775-foaf3vyl 153 5 in in IN cord-004775-foaf3vyl 153 6 the the DT cord-004775-foaf3vyl 153 7 cytoplasm cytoplasm NN cord-004775-foaf3vyl 153 8 and and CC cord-004775-foaf3vyl 153 9 nucleus nucleus NN cord-004775-foaf3vyl 153 10 and and CC cord-004775-foaf3vyl 153 11 enveloped envelop VBD cord-004775-foaf3vyl 153 12 viral viral JJ cord-004775-foaf3vyl 153 13 particles particle NNS cord-004775-foaf3vyl 153 14 were be VBD cord-004775-foaf3vyl 153 15 seen see VBN cord-004775-foaf3vyl 153 16 predominantly predominantly RB cord-004775-foaf3vyl 153 17 in in IN cord-004775-foaf3vyl 153 18 vesicles vesicle NNS cord-004775-foaf3vyl 153 19 of of IN cord-004775-foaf3vyl 153 20 the the DT cord-004775-foaf3vyl 153 21 Golgi Golgi NNP cord-004775-foaf3vyl 153 22 system system NN cord-004775-foaf3vyl 153 23 . . . cord-004775-foaf3vyl 154 1 Virus virus NN cord-004775-foaf3vyl 154 2 containing contain VBG cord-004775-foaf3vyl 154 3 vesicles vesicle NNS cord-004775-foaf3vyl 154 4 appear appear VBP cord-004775-foaf3vyl 154 5 to to TO cord-004775-foaf3vyl 154 6 move move VB cord-004775-foaf3vyl 154 7 to to IN cord-004775-foaf3vyl 154 8 the the DT cord-004775-foaf3vyl 154 9 cell cell NN cord-004775-foaf3vyl 154 10 surface surface NN cord-004775-foaf3vyl 154 11 and and CC cord-004775-foaf3vyl 154 12 to to TO cord-004775-foaf3vyl 154 13 release release VB cord-004775-foaf3vyl 154 14 their -PRON- PRP$ cord-004775-foaf3vyl 154 15 contents content NNS cord-004775-foaf3vyl 154 16 by by IN cord-004775-foaf3vyl 154 17 fusion fusion NN cord-004775-foaf3vyl 154 18 with with IN cord-004775-foaf3vyl 154 19 the the DT cord-004775-foaf3vyl 154 20 plasma plasma NN cord-004775-foaf3vyl 154 21 membrane membrane NN cord-004775-foaf3vyl 154 22 . . . cord-004775-foaf3vyl 155 1 All all DT cord-004775-foaf3vyl 155 2 BRV BRV NNP cord-004775-foaf3vyl 155 3 particles particle NNS cord-004775-foaf3vyl 155 4 encountered encounter VBN cord-004775-foaf3vyl 155 5 in in IN cord-004775-foaf3vyl 155 6 ultrathin ultrathin JJ cord-004775-foaf3vyl 155 7 sections section NNS cord-004775-foaf3vyl 155 8 were be VBD cord-004775-foaf3vyl 155 9 elongated elongated JJ cord-004775-foaf3vyl 155 10 and and CC cord-004775-foaf3vyl 155 11 bacilliform bacilliform NNS cord-004775-foaf3vyl 155 12 . . . cord-004775-foaf3vyl 156 1 Berne Berne NNP cord-004775-foaf3vyl 156 2 virus virus NN cord-004775-foaf3vyl 156 3 was be VBD cord-004775-foaf3vyl 156 4 isolated isolate VBN cord-004775-foaf3vyl 156 5 from from IN cord-004775-foaf3vyl 156 6 a a DT cord-004775-foaf3vyl 156 7 rectal rectal JJ cord-004775-foaf3vyl 156 8 swab swab NN cord-004775-foaf3vyl 156 9 of of IN cord-004775-foaf3vyl 156 10 a a DT cord-004775-foaf3vyl 156 11 diarrheic diarrheic NN cord-004775-foaf3vyl 156 12 horse horse NN cord-004775-foaf3vyl 156 13 ( ( -LRB- cord-004775-foaf3vyl 156 14 2 2 CD cord-004775-foaf3vyl 156 15 ) ) -RRB- cord-004775-foaf3vyl 156 16 ; ; : cord-004775-foaf3vyl 156 17 whether whether IN cord-004775-foaf3vyl 156 18 it -PRON- PRP cord-004775-foaf3vyl 156 19 had have VBD cord-004775-foaf3vyl 156 20 caused cause VBN cord-004775-foaf3vyl 156 21 this this DT cord-004775-foaf3vyl 156 22 disease disease NN cord-004775-foaf3vyl 156 23 could could MD cord-004775-foaf3vyl 156 24 not not RB cord-004775-foaf3vyl 156 25 be be VB cord-004775-foaf3vyl 156 26 proven prove VBN cord-004775-foaf3vyl 156 27 . . . cord-004775-foaf3vyl 157 1 In in IN cord-004775-foaf3vyl 157 2 a a DT cord-004775-foaf3vyl 157 3 few few JJ cord-004775-foaf3vyl 157 4 experimental experimental JJ cord-004775-foaf3vyl 157 5 and and CC cord-004775-foaf3vyl 157 6 naturally naturally RB cord-004775-foaf3vyl 157 7 oecuring oecure VBG cord-004775-foaf3vyl 157 8 BEV BEV NNP cord-004775-foaf3vyl 157 9 infections infection NNS cord-004775-foaf3vyl 157 10 clinical clinical JJ cord-004775-foaf3vyl 157 11 signs sign NNS cord-004775-foaf3vyl 157 12 were be VBD cord-004775-foaf3vyl 157 13 not not RB cord-004775-foaf3vyl 157 14 noted note VBN cord-004775-foaf3vyl 157 15 ( ( -LRB- cord-004775-foaf3vyl 157 16 18 18 CD cord-004775-foaf3vyl 157 17 ) ) -RRB- cord-004775-foaf3vyl 157 18 . . . cord-004775-foaf3vyl 158 1 Consequently consequently RB cord-004775-foaf3vyl 158 2 , , , cord-004775-foaf3vyl 158 3 a a DT cord-004775-foaf3vyl 158 4 disease disease NN cord-004775-foaf3vyl 158 5 picture picture NN cord-004775-foaf3vyl 158 6 can can MD cord-004775-foaf3vyl 158 7 not not RB cord-004775-foaf3vyl 158 8 be be VB cord-004775-foaf3vyl 158 9 attributed attribute VBN cord-004775-foaf3vyl 158 10 to to IN cord-004775-foaf3vyl 158 11 BEV BEV NNP cord-004775-foaf3vyl 158 12 so so RB cord-004775-foaf3vyl 158 13 far far RB cord-004775-foaf3vyl 158 14 . . . cord-004775-foaf3vyl 159 1 BRV BRV NNP cord-004775-foaf3vyl 159 2 in in IN cord-004775-foaf3vyl 159 3 contrast contrast NN cord-004775-foaf3vyl 159 4 , , , cord-004775-foaf3vyl 159 5 was be VBD cord-004775-foaf3vyl 159 6 first first RB cord-004775-foaf3vyl 159 7 isolated isolate VBN cord-004775-foaf3vyl 159 8 during during IN cord-004775-foaf3vyl 159 9 an an DT cord-004775-foaf3vyl 159 10 acute acute JJ cord-004775-foaf3vyl 159 11 epizootic epizootic NN cord-004775-foaf3vyl 159 12 of of IN cord-004775-foaf3vyl 159 13 calf calf NN cord-004775-foaf3vyl 159 14 diarrhea diarrhea NN cord-004775-foaf3vyl 159 15 ( ( -LRB- cord-004775-foaf3vyl 159 16 1 1 CD cord-004775-foaf3vyl 159 17 ) ) -RRB- cord-004775-foaf3vyl 159 18 , , , cord-004775-foaf3vyl 159 19 and and CC cord-004775-foaf3vyl 159 20 was be VBD cord-004775-foaf3vyl 159 21 later later RB cord-004775-foaf3vyl 159 22 shown show VBN cord-004775-foaf3vyl 159 23 to to TO cord-004775-foaf3vyl 159 24 cause cause VB cord-004775-foaf3vyl 159 25 diarrhea diarrhea NN cord-004775-foaf3vyl 159 26 of of IN cord-004775-foaf3vyl 159 27 varying vary VBG cord-004775-foaf3vyl 159 28 severity severity NN cord-004775-foaf3vyl 159 29 , , , cord-004775-foaf3vyl 159 30 both both CC cord-004775-foaf3vyl 159 31 in in IN cord-004775-foaf3vyl 159 32 colostrum colostrum NN cord-004775-foaf3vyl 159 33 - - HYPH cord-004775-foaf3vyl 159 34 deprived deprive VBN cord-004775-foaf3vyl 159 35 and and CC cord-004775-foaf3vyl 159 36 gnotobiotic gnotobiotic JJ cord-004775-foaf3vyl 159 37 calves calf NNS cord-004775-foaf3vyl 159 38 ( ( -LRB- cord-004775-foaf3vyl 159 39 11 11 CD cord-004775-foaf3vyl 159 40 , , , cord-004775-foaf3vyl 159 41 17 17 CD cord-004775-foaf3vyl 159 42 ) ) -RRB- cord-004775-foaf3vyl 159 43 . . . cord-004775-foaf3vyl 160 1 In in IN cord-004775-foaf3vyl 160 2 man man NN cord-004775-foaf3vyl 160 3 the the DT cord-004775-foaf3vyl 160 4 torovirus torovirus NNP cord-004775-foaf3vyl 160 5 - - HYPH cord-004775-foaf3vyl 160 6 like like JJ cord-004775-foaf3vyl 160 7 particles particle NNS cord-004775-foaf3vyl 160 8 were be VBD cord-004775-foaf3vyl 160 9 also also RB cord-004775-foaf3vyl 160 10 found find VBN cord-004775-foaf3vyl 160 11 in in IN cord-004775-foaf3vyl 160 12 association association NN cord-004775-foaf3vyl 160 13 with with IN cord-004775-foaf3vyl 160 14 diarrhea diarrhea NN cord-004775-foaf3vyl 160 15 ( ( -LRB- cord-004775-foaf3vyl 160 16 8) 8) NN cord-004775-foaf3vyl 160 17 . . . cord-004775-foaf3vyl 161 1 Pathological pathological JJ cord-004775-foaf3vyl 161 2 and and CC cord-004775-foaf3vyl 161 3 histopathological histopathological JJ cord-004775-foaf3vyl 161 4 data datum NNS cord-004775-foaf3vyl 161 5 are be VBP cord-004775-foaf3vyl 161 6 only only RB cord-004775-foaf3vyl 161 7 available available JJ cord-004775-foaf3vyl 161 8 from from IN cord-004775-foaf3vyl 161 9 BRV BRV NNP cord-004775-foaf3vyl 161 10 infected infected JJ cord-004775-foaf3vyl 161 11 calves calf NNS cord-004775-foaf3vyl 161 12 ( ( -LRB- cord-004775-foaf3vyl 161 13 1 1 CD cord-004775-foaf3vyl 161 14 , , , cord-004775-foaf3vyl 161 15 10 10 CD cord-004775-foaf3vyl 161 16 , , , cord-004775-foaf3vyl 161 17 I1 i1 NN cord-004775-foaf3vyl 161 18 ) ) -RRB- cord-004775-foaf3vyl 161 19 . . . cord-004775-foaf3vyl 162 1 Lesions lesion NNS cord-004775-foaf3vyl 162 2 were be VBD cord-004775-foaf3vyl 162 3 seen see VBN cord-004775-foaf3vyl 162 4 in in IN cord-004775-foaf3vyl 162 5 the the DT cord-004775-foaf3vyl 162 6 intestinal intestinal JJ cord-004775-foaf3vyl 162 7 mueosa mueosa NN cord-004775-foaf3vyl 162 8 of of IN cord-004775-foaf3vyl 162 9 the the DT cord-004775-foaf3vyl 162 10 middle middle NN cord-004775-foaf3vyl 162 11 to to IN cord-004775-foaf3vyl 162 12 caudal caudal JJ cord-004775-foaf3vyl 162 13 part part NN cord-004775-foaf3vyl 162 14 of of IN cord-004775-foaf3vyl 162 15 the the DT cord-004775-foaf3vyl 162 16 jejunum jejunum NNS cord-004775-foaf3vyl 162 17 , , , cord-004775-foaf3vyl 162 18 of of IN cord-004775-foaf3vyl 162 19 the the DT cord-004775-foaf3vyl 162 20 ileum ileum NN cord-004775-foaf3vyl 162 21 , , , cord-004775-foaf3vyl 162 22 cecum cecum NN cord-004775-foaf3vyl 162 23 , , , cord-004775-foaf3vyl 162 24 spiral spiral JJ cord-004775-foaf3vyl 162 25 colon colon NN cord-004775-foaf3vyl 162 26 and and CC cord-004775-foaf3vyl 162 27 descending descend VBG cord-004775-foaf3vyl 162 28 colon colon NN cord-004775-foaf3vyl 162 29 . . . cord-004775-foaf3vyl 163 1 They -PRON- PRP cord-004775-foaf3vyl 163 2 consisted consist VBD cord-004775-foaf3vyl 163 3 of of IN cord-004775-foaf3vyl 163 4 villus villus NN cord-004775-foaf3vyl 163 5 atrophy atrophy NN cord-004775-foaf3vyl 163 6 and and CC cord-004775-foaf3vyl 163 7 necrosis necrosis NN cord-004775-foaf3vyl 163 8 of of IN cord-004775-foaf3vyl 163 9 epithelial epithelial JJ cord-004775-foaf3vyl 163 10 cells cell NNS cord-004775-foaf3vyl 163 11 covering cover VBG cord-004775-foaf3vyl 163 12 villi villus NNS cord-004775-foaf3vyl 163 13 and and CC cord-004775-foaf3vyl 163 14 crypts crypt NNS cord-004775-foaf3vyl 163 15 . . . cord-004775-foaf3vyl 164 1 In in IN cord-004775-foaf3vyl 164 2 addition addition NN cord-004775-foaf3vyl 164 3 , , , cord-004775-foaf3vyl 164 4 an an DT cord-004775-foaf3vyl 164 5 acute acute JJ cord-004775-foaf3vyl 164 6 inflammatory inflammatory JJ cord-004775-foaf3vyl 164 7 response response NN cord-004775-foaf3vyl 164 8 with with IN cord-004775-foaf3vyl 164 9 cellular cellular JJ cord-004775-foaf3vyl 164 10 infiltration infiltration NN cord-004775-foaf3vyl 164 11 and and CC cord-004775-foaf3vyl 164 12 subtle subtle JJ cord-004775-foaf3vyl 164 13 changes change NNS cord-004775-foaf3vyl 164 14 in in IN cord-004775-foaf3vyl 164 15 capillaries capillary NNS cord-004775-foaf3vyl 164 16 were be VBD cord-004775-foaf3vyl 164 17 noted note VBN cord-004775-foaf3vyl 164 18 in in IN cord-004775-foaf3vyl 164 19 the the DT cord-004775-foaf3vyl 164 20 altered altered JJ cord-004775-foaf3vyl 164 21 regions region NNS cord-004775-foaf3vyl 164 22 . . . cord-004775-foaf3vyl 165 1 The the DT cord-004775-foaf3vyl 165 2 infected infected JJ cord-004775-foaf3vyl 165 3 cells cell NNS cord-004775-foaf3vyl 165 4 showed show VBD cord-004775-foaf3vyl 165 5 a a DT cord-004775-foaf3vyl 165 6 distension distension NN cord-004775-foaf3vyl 165 7 of of IN cord-004775-foaf3vyl 165 8 the the DT cord-004775-foaf3vyl 165 9 cytocavitary cytocavitary NNP cord-004775-foaf3vyl 165 10 network network NN cord-004775-foaf3vyl 165 11 , , , cord-004775-foaf3vyl 165 12 a a DT cord-004775-foaf3vyl 165 13 dilation dilation NN cord-004775-foaf3vyl 165 14 of of IN cord-004775-foaf3vyl 165 15 the the DT cord-004775-foaf3vyl 165 16 Golgi Golgi NNP cord-004775-foaf3vyl 165 17 complex complex NN cord-004775-foaf3vyl 165 18 , , , cord-004775-foaf3vyl 165 19 the the DT cord-004775-foaf3vyl 165 20 appearance appearance NN cord-004775-foaf3vyl 165 21 of of IN cord-004775-foaf3vyl 165 22 autophagolysosomes autophagolysosomes NNP cord-004775-foaf3vyl 165 23 , , , cord-004775-foaf3vyl 165 24 shortened shorten VBD cord-004775-foaf3vyl 165 25 mierovilli mierovilli NNP cord-004775-foaf3vyl 165 26 and and CC cord-004775-foaf3vyl 165 27 degenerated degenerate VBD cord-004775-foaf3vyl 165 28 mitochondria mitochondrion NNS cord-004775-foaf3vyl 165 29 . . . cord-004775-foaf3vyl 166 1 Viral viral JJ cord-004775-foaf3vyl 166 2 antigen antigen NN cord-004775-foaf3vyl 166 3 and and CC cord-004775-foaf3vyl 166 4 particles particle NNS cord-004775-foaf3vyl 166 5 could could MD cord-004775-foaf3vyl 166 6 be be VB cord-004775-foaf3vyl 166 7 demonstrated demonstrate VBN cord-004775-foaf3vyl 166 8 in in IN cord-004775-foaf3vyl 166 9 the the DT cord-004775-foaf3vyl 166 10 affected affected JJ cord-004775-foaf3vyl 166 11 parts part NNS cord-004775-foaf3vyl 166 12 of of IN cord-004775-foaf3vyl 166 13 the the DT cord-004775-foaf3vyl 166 14 intestine intestine NN cord-004775-foaf3vyl 166 15 by by IN cord-004775-foaf3vyl 166 16 indirect indirect JJ cord-004775-foaf3vyl 166 17 IF if NN cord-004775-foaf3vyl 166 18 and and CC cord-004775-foaf3vyl 166 19 EM EM NNP cord-004775-foaf3vyl 166 20 , , , cord-004775-foaf3vyl 166 21 respectively respectively RB cord-004775-foaf3vyl 166 22 . . . cord-004775-foaf3vyl 167 1 Toroviruses toroviruse NNS cord-004775-foaf3vyl 167 2 have have VBP cord-004775-foaf3vyl 167 3 been be VBN cord-004775-foaf3vyl 167 4 demonstrated demonstrate VBN cord-004775-foaf3vyl 167 5 in in IN cord-004775-foaf3vyl 167 6 the the DT cord-004775-foaf3vyl 167 7 horse horse NN cord-004775-foaf3vyl 167 8 , , , cord-004775-foaf3vyl 167 9 in in IN cord-004775-foaf3vyl 167 10 cattle cattle NNS cord-004775-foaf3vyl 167 11 and and CC cord-004775-foaf3vyl 167 12 man man NN cord-004775-foaf3vyl 167 13 , , , cord-004775-foaf3vyl 167 14 and and CC cord-004775-foaf3vyl 167 15 they -PRON- PRP cord-004775-foaf3vyl 167 16 were be VBD cord-004775-foaf3vyl 167 17 occasionally occasionally RB cord-004775-foaf3vyl 167 18 seen see VBN cord-004775-foaf3vyl 167 19 in in IN cord-004775-foaf3vyl 167 20 pigs pig NNS cord-004775-foaf3vyl 167 21 ( ( -LRB- cord-004775-foaf3vyl 167 22 SAIF SAIF NNP cord-004775-foaf3vyl 167 23 , , , cord-004775-foaf3vyl 167 24 unpublished unpublished JJ cord-004775-foaf3vyl 167 25 results result NNS cord-004775-foaf3vyl 167 26 ) ) -RRB- cord-004775-foaf3vyl 167 27 . . . cord-004775-foaf3vyl 168 1 These these DT cord-004775-foaf3vyl 168 2 are be VBP cord-004775-foaf3vyl 168 3 not not RB cord-004775-foaf3vyl 168 4 the the DT cord-004775-foaf3vyl 168 5 only only JJ cord-004775-foaf3vyl 168 6 host host NN cord-004775-foaf3vyl 168 7 species specie NNS cord-004775-foaf3vyl 168 8 of of IN cord-004775-foaf3vyl 168 9 toroviruses toroviruse NNS cord-004775-foaf3vyl 168 10 . . . cord-004775-foaf3vyl 169 1 From from IN cord-004775-foaf3vyl 169 2 serological serological JJ cord-004775-foaf3vyl 169 3 examinations examination NNS cord-004775-foaf3vyl 169 4 evidence evidence NN cord-004775-foaf3vyl 169 5 was be VBD cord-004775-foaf3vyl 169 6 obtained obtain VBN cord-004775-foaf3vyl 169 7 that that IN cord-004775-foaf3vyl 169 8 BEV BEV NNP cord-004775-foaf3vyl 169 9 - - HYPH cord-004775-foaf3vyl 169 10 related relate VBN cord-004775-foaf3vyl 169 11 viruses virus NNS cord-004775-foaf3vyl 169 12 are be VBP cord-004775-foaf3vyl 169 13 prevalent prevalent JJ cord-004775-foaf3vyl 169 14 in in IN cord-004775-foaf3vyl 169 15 other other JJ cord-004775-foaf3vyl 169 16 ungulates ungulate NNS cord-004775-foaf3vyl 169 17 ( ( -LRB- cord-004775-foaf3vyl 169 18 cattle cattle NNS cord-004775-foaf3vyl 169 19 , , , cord-004775-foaf3vyl 169 20 goat goat NN cord-004775-foaf3vyl 169 21 , , , cord-004775-foaf3vyl 169 22 sheep sheep NN cord-004775-foaf3vyl 169 23 , , , cord-004775-foaf3vyl 169 24 pig pig NN cord-004775-foaf3vyl 169 25 ) ) -RRB- cord-004775-foaf3vyl 169 26 , , , cord-004775-foaf3vyl 169 27 in in IN cord-004775-foaf3vyl 169 28 tbral tbral JJ cord-004775-foaf3vyl 169 29 mice mouse NNS cord-004775-foaf3vyl 169 30 and and CC cord-004775-foaf3vyl 169 31 in in IN cord-004775-foaf3vyl 169 32 laboratory laboratory NN cord-004775-foaf3vyl 169 33 rabbits rabbit NNS cord-004775-foaf3vyl 169 34 ( ( -LRB- cord-004775-foaf3vyl 169 35 18 18 CD cord-004775-foaf3vyl 169 36 ) ) -RRB- cord-004775-foaf3vyl 169 37 . . . cord-004775-foaf3vyl 170 1 In in IN cord-004775-foaf3vyl 170 2 86 86 CD cord-004775-foaf3vyl 170 3 per per NN cord-004775-foaf3vyl 170 4 cent cent NN cord-004775-foaf3vyl 170 5 of of IN cord-004775-foaf3vyl 170 6 cattle cattle NNS cord-004775-foaf3vyl 170 7 , , , cord-004775-foaf3vyl 170 8 69 69 CD cord-004775-foaf3vyl 170 9 per per IN cord-004775-foaf3vyl 170 10 cent cent NN cord-004775-foaf3vyl 170 11 of of IN cord-004775-foaf3vyl 170 12 goat goat NN cord-004775-foaf3vyl 170 13 , , , cord-004775-foaf3vyl 170 14 34 34 CD cord-004775-foaf3vyl 170 15 per per IN cord-004775-foaf3vyl 170 16 cent cent NN cord-004775-foaf3vyl 170 17 of of IN cord-004775-foaf3vyl 170 18 sheep sheep NN cord-004775-foaf3vyl 170 19 , , , cord-004775-foaf3vyl 170 20 and and CC cord-004775-foaf3vyl 170 21 74 74 CD cord-004775-foaf3vyl 170 22 per per NN cord-004775-foaf3vyl 170 23 cent cent NN cord-004775-foaf3vyl 170 24 of of IN cord-004775-foaf3vyl 170 25 pig pig NNP cord-004775-foaf3vyl 170 26 sera sera NNP cord-004775-foaf3vyl 170 27 tested test VBD cord-004775-foaf3vyl 170 28 high high JJ cord-004775-foaf3vyl 170 29 antibody antibody NN cord-004775-foaf3vyl 170 30 tigers tiger NNS cord-004775-foaf3vyl 170 31 cross cross NN cord-004775-foaf3vyl 170 32 - - JJ cord-004775-foaf3vyl 170 33 reacting react VBG cord-004775-foaf3vyl 170 34 with with IN cord-004775-foaf3vyl 170 35 BEV BEV NNP cord-004775-foaf3vyl 170 36 in in IN cord-004775-foaf3vyl 170 37 seroneutralization seroneutralization NN cord-004775-foaf3vyl 170 38 were be VBD cord-004775-foaf3vyl 170 39 detected detect VBN cord-004775-foaf3vyl 170 40 . . . cord-004775-foaf3vyl 171 1 Low low JJ cord-004775-foaf3vyl 171 2 neutralization neutralization NN cord-004775-foaf3vyl 171 3 titers titer NNS cord-004775-foaf3vyl 171 4 were be VBD cord-004775-foaf3vyl 171 5 found find VBN cord-004775-foaf3vyl 171 6 in in IN cord-004775-foaf3vyl 171 7 sera sera NNP cord-004775-foaf3vyl 171 8 of of IN cord-004775-foaf3vyl 171 9 laboratory laboratory NN cord-004775-foaf3vyl 171 10 rabbits rabbit NNS cord-004775-foaf3vyl 171 11 and and CC cord-004775-foaf3vyl 171 12 in in IN cord-004775-foaf3vyl 171 13 two two CD cord-004775-foaf3vyl 171 14 species specie NNS cord-004775-foaf3vyl 171 15 of of IN cord-004775-foaf3vyl 171 16 wild wild JJ cord-004775-foaf3vyl 171 17 mice mouse NNS cord-004775-foaf3vyl 171 18 ( ( -LRB- cord-004775-foaf3vyl 171 19 Apodemus Apodemus NNP cord-004775-foaf3vyl 171 20 sylvaticus sylvaticus NNP cord-004775-foaf3vyl 171 21 , , , cord-004775-foaf3vyl 171 22 CIethrionomys CIethrionomys NNP cord-004775-foaf3vyl 171 23 glareolus glareolus NNP cord-004775-foaf3vyl 171 24 ) ) -RRB- cord-004775-foaf3vyl 171 25 ; ; : cord-004775-foaf3vyl 171 26 they -PRON- PRP cord-004775-foaf3vyl 171 27 may may MD cord-004775-foaf3vyl 171 28 indicate indicate VB cord-004775-foaf3vyl 171 29 the the DT cord-004775-foaf3vyl 171 30 presence presence NN cord-004775-foaf3vyl 171 31 of of IN cord-004775-foaf3vyl 171 32 more more RBR cord-004775-foaf3vyl 171 33 distant distant JJ cord-004775-foaf3vyl 171 34 serotypes serotype NNS cord-004775-foaf3vyl 171 35 . . . cord-004775-foaf3vyl 172 1 The the DT cord-004775-foaf3vyl 172 2 high high JJ cord-004775-foaf3vyl 172 3 tigers tiger NNS cord-004775-foaf3vyl 172 4 encountered encounter VBN cord-004775-foaf3vyl 172 5 in in IN cord-004775-foaf3vyl 172 6 ungulates ungulate NNS cord-004775-foaf3vyl 172 7 , , , cord-004775-foaf3vyl 172 8 however however RB cord-004775-foaf3vyl 172 9 , , , cord-004775-foaf3vyl 172 10 are be VBP cord-004775-foaf3vyl 172 11 thought think VBN cord-004775-foaf3vyl 172 12 to to TO cord-004775-foaf3vyl 172 13 be be VB cord-004775-foaf3vyl 172 14 due due JJ cord-004775-foaf3vyl 172 15 to to IN cord-004775-foaf3vyl 172 16 viruses virus NNS cord-004775-foaf3vyl 172 17 serologically serologically RB cord-004775-foaf3vyl 172 18 more more RBR cord-004775-foaf3vyl 172 19 closely closely RB cord-004775-foaf3vyl 172 20 related related JJ cord-004775-foaf3vyl 172 21 to to IN cord-004775-foaf3vyl 172 22 BEV BEV NNP cord-004775-foaf3vyl 172 23 . . . cord-004775-foaf3vyl 173 1 Neutralization neutralization NN cord-004775-foaf3vyl 173 2 tests test NNS cord-004775-foaf3vyl 173 3 are be VBP cord-004775-foaf3vyl 173 4 known know VBN cord-004775-foaf3vyl 173 5 to to TO cord-004775-foaf3vyl 173 6 be be VB cord-004775-foaf3vyl 173 7 very very RB cord-004775-foaf3vyl 173 8 sensitive sensitive JJ cord-004775-foaf3vyl 173 9 and and CC cord-004775-foaf3vyl 173 10 specific specific JJ cord-004775-foaf3vyl 173 11 . . . cord-004775-foaf3vyl 174 1 Assays assay NNS cord-004775-foaf3vyl 174 2 for for IN cord-004775-foaf3vyl 174 3 group group NN cord-004775-foaf3vyl 174 4 specific specific JJ cord-004775-foaf3vyl 174 5 antigens antigen NNS cord-004775-foaf3vyl 174 6 should should MD cord-004775-foaf3vyl 174 7 elucidate elucidate VB cord-004775-foaf3vyl 174 8 the the DT cord-004775-foaf3vyl 174 9 actual actual JJ cord-004775-foaf3vyl 174 10 prevalence prevalence NN cord-004775-foaf3vyl 174 11 of of IN cord-004775-foaf3vyl 174 12 toroviruses toroviruse NNS cord-004775-foaf3vyl 174 13 in in IN cord-004775-foaf3vyl 174 14 different different JJ cord-004775-foaf3vyl 174 15 animal animal NN cord-004775-foaf3vyl 174 16 species specie NNS cord-004775-foaf3vyl 174 17 and and CC cord-004775-foaf3vyl 174 18 probably probably RB cord-004775-foaf3vyl 174 19 explain explain VB cord-004775-foaf3vyl 174 20 erratic erratic JJ cord-004775-foaf3vyl 174 21 inhibitions inhibition NNS cord-004775-foaf3vyl 174 22 obtained obtain VBN cord-004775-foaf3vyl 174 23 with with IN cord-004775-foaf3vyl 174 24 feline feline JJ cord-004775-foaf3vyl 174 25 and and CC cord-004775-foaf3vyl 174 26 human human JJ cord-004775-foaf3vyl 174 27 sera sera NNP cord-004775-foaf3vyl 174 28 in in IN cord-004775-foaf3vyl 174 29 the the DT cord-004775-foaf3vyl 174 30 seroneutralization seroneutralization NN cord-004775-foaf3vyl 174 31 tests test VBZ cord-004775-foaf3vyl 174 32 . . . cord-004775-foaf3vyl 175 1 It -PRON- PRP cord-004775-foaf3vyl 175 2 is be VBZ cord-004775-foaf3vyl 175 3 not not RB cord-004775-foaf3vyl 175 4 known know VBN cord-004775-foaf3vyl 175 5 whether whether IN cord-004775-foaf3vyl 175 6 toroviruses toroviruse NNS cord-004775-foaf3vyl 175 7 are be VBP cord-004775-foaf3vyl 175 8 restricted restrict VBN cord-004775-foaf3vyl 175 9 to to IN cord-004775-foaf3vyl 175 10 their -PRON- PRP$ cord-004775-foaf3vyl 175 11 respective respective JJ cord-004775-foaf3vyl 175 12 hosts host NNS cord-004775-foaf3vyl 175 13 or or CC cord-004775-foaf3vyl 175 14 interspecies interspecies NN cord-004775-foaf3vyl 175 15 transmission transmission NN cord-004775-foaf3vyl 175 16 Occurs occur VBZ cord-004775-foaf3vyl 175 17 . . . cord-004775-foaf3vyl 176 1 Toroviruses toroviruse NNS cord-004775-foaf3vyl 176 2 are be VBP cord-004775-foaf3vyl 176 3 widespread widespread JJ cord-004775-foaf3vyl 176 4 in in IN cord-004775-foaf3vyl 176 5 horse horse NN cord-004775-foaf3vyl 176 6 and and CC cord-004775-foaf3vyl 176 7 cattle cattle NNS cord-004775-foaf3vyl 176 8 populations population NNS cord-004775-foaf3vyl 176 9 as as IN cord-004775-foaf3vyl 176 10 evidenced evidence VBN cord-004775-foaf3vyl 176 11 by by IN cord-004775-foaf3vyl 176 12 the the DT cord-004775-foaf3vyl 176 13 presence presence NN cord-004775-foaf3vyl 176 14 of of IN cord-004775-foaf3vyl 176 15 antibody antibody NN cord-004775-foaf3vyl 176 16 titers titer NNS cord-004775-foaf3vyl 176 17 . . . cord-004775-foaf3vyl 177 1 In in IN cord-004775-foaf3vyl 177 2 Switzerland Switzerland NNP cord-004775-foaf3vyl 177 3 , , , cord-004775-foaf3vyl 177 4 80 80 CD cord-004775-foaf3vyl 177 5 per per NN cord-004775-foaf3vyl 177 6 cent cent NN cord-004775-foaf3vyl 177 7 of of IN cord-004775-foaf3vyl 177 8 randomly randomly RB cord-004775-foaf3vyl 177 9 collected collect VBN cord-004775-foaf3vyl 177 10 sera sera NNP cord-004775-foaf3vyl 178 1 ( ( -LRB- cord-004775-foaf3vyl 178 2 n= n= NNP cord-004775-foaf3vyl 178 3 500 500 CD cord-004775-foaf3vyl 178 4 ) ) -RRB- cord-004775-foaf3vyl 178 5 from from IN cord-004775-foaf3vyl 178 6 adult adult NN cord-004775-foaf3vyl 178 7 horses horse NNS cord-004775-foaf3vyl 178 8 contained contain VBD cord-004775-foaf3vyl 178 9 antibodies antibody NNS cord-004775-foaf3vyl 178 10 reacting react VBG cord-004775-foaf3vyl 178 11 with with IN cord-004775-foaf3vyl 178 12 BEV BEV NNP cord-004775-foaf3vyl 178 13 in in IN cord-004775-foaf3vyl 178 14 a a DT cord-004775-foaf3vyl 178 15 seroneutralization seroneutralization NN cord-004775-foaf3vyl 178 16 test test NN cord-004775-foaf3vyl 178 17 . . . cord-004775-foaf3vyl 179 1 Antibodies antibody NNS cord-004775-foaf3vyl 179 2 against against IN cord-004775-foaf3vyl 179 3 BEV BEV NNP cord-004775-foaf3vyl 179 4 were be VBD cord-004775-foaf3vyl 179 5 also also RB cord-004775-foaf3vyl 179 6 encountered encounter VBN cord-004775-foaf3vyl 179 7 in in IN cord-004775-foaf3vyl 179 8 small small JJ cord-004775-foaf3vyl 179 9 numbers number NNS cord-004775-foaf3vyl 179 10 of of IN cord-004775-foaf3vyl 179 11 randomly randomly RB cord-004775-foaf3vyl 179 12 collected collect VBN cord-004775-foaf3vyl 179 13 equine equine JJ cord-004775-foaf3vyl 179 14 sera sera NNP cord-004775-foaf3vyl 179 15 from from IN cord-004775-foaf3vyl 179 16 Germany Germany NNP cord-004775-foaf3vyl 179 17 , , , cord-004775-foaf3vyl 179 18 France France NNP cord-004775-foaf3vyl 179 19 , , , cord-004775-foaf3vyl 179 20 Italy Italy NNP cord-004775-foaf3vyl 179 21 and and CC cord-004775-foaf3vyl 179 22 the the DT cord-004775-foaf3vyl 179 23 U.S.A. U.S.A. NNP cord-004775-foaf3vyl 179 24 ( ( -LRB- cord-004775-foaf3vyl 179 25 18 18 CD cord-004775-foaf3vyl 179 26 ) ) -RRB- cord-004775-foaf3vyl 179 27 . . . cord-004775-foaf3vyl 180 1 In in IN cord-004775-foaf3vyl 180 2 cattle cattle NNS cord-004775-foaf3vyl 180 3 sera sera NNP cord-004775-foaf3vyl 180 4 from from IN cord-004775-foaf3vyl 180 5 the the DT cord-004775-foaf3vyl 180 6 U.S.A. U.S.A. NNP cord-004775-foaf3vyl 180 7 ( ( -LRB- cord-004775-foaf3vyl 180 8 n n NN cord-004775-foaf3vyl 180 9 = = SYM cord-004775-foaf3vyl 180 10 156 156 CD cord-004775-foaf3vyl 180 11 ) ) -RRB- cord-004775-foaf3vyl 180 12 88.5 88.5 CD cord-004775-foaf3vyl 180 13 per per IN cord-004775-foaf3vyl 180 14 cent cent NN cord-004775-foaf3vyl 180 15 were be VBD cord-004775-foaf3vyl 180 16 reported report VBN cord-004775-foaf3vyl 180 17 positive positive JJ cord-004775-foaf3vyl 180 18 in in IN cord-004775-foaf3vyl 180 19 an an DT cord-004775-foaf3vyl 180 20 ELISA ELISA NNP cord-004775-foaf3vyl 180 21 using use VBG cord-004775-foaf3vyl 180 22 BRV BRV NNP cord-004775-foaf3vyl 180 23 as as IN cord-004775-foaf3vyl 180 24 an an DT cord-004775-foaf3vyl 180 25 antigen antigen NN cord-004775-foaf3vyl 180 26 ( ( -LRB- cord-004775-foaf3vyl 180 27 t9 t9 NNP cord-004775-foaf3vyl 180 28 ) ) -RRB- cord-004775-foaf3vyl 180 29 . . . cord-004775-foaf3vyl 181 1 The the DT cord-004775-foaf3vyl 181 2 way way NN cord-004775-foaf3vyl 181 3 of of IN cord-004775-foaf3vyl 181 4 spread spread NN cord-004775-foaf3vyl 181 5 of of IN cord-004775-foaf3vyl 181 6 torovirus torovirus NNP cord-004775-foaf3vyl 181 7 infections infection NNS cord-004775-foaf3vyl 181 8 is be VBZ cord-004775-foaf3vyl 181 9 not not RB cord-004775-foaf3vyl 181 10 known know VBN cord-004775-foaf3vyl 181 11 . . . cord-004775-foaf3vyl 182 1 BRV BRV NNP cord-004775-foaf3vyl 182 2 was be VBD cord-004775-foaf3vyl 182 3 experimentally experimentally RB cord-004775-foaf3vyl 182 4 transmitted transmit VBN cord-004775-foaf3vyl 182 5 by by IN cord-004775-foaf3vyl 182 6 oral oral JJ cord-004775-foaf3vyl 182 7 administration administration NN cord-004775-foaf3vyl 182 8 ( ( -LRB- cord-004775-foaf3vyl 182 9 1 1 CD cord-004775-foaf3vyl 182 10 , , , cord-004775-foaf3vyl 182 11 11 11 CD cord-004775-foaf3vyl 182 12 ) ) -RRB- cord-004775-foaf3vyl 182 13 , , , cord-004775-foaf3vyl 182 14 and and CC cord-004775-foaf3vyl 182 15 an an DT cord-004775-foaf3vyl 182 16 oral oral JJ cord-004775-foaf3vyl 182 17 - - HYPH cord-004775-foaf3vyl 182 18 fecal fecal NN cord-004775-foaf3vyl 182 19 route route NN cord-004775-foaf3vyl 182 20 of of IN cord-004775-foaf3vyl 182 21 transmission transmission NN cord-004775-foaf3vyl 182 22 is be VBZ cord-004775-foaf3vyl 182 23 likely likely JJ cord-004775-foaf3vyl 182 24 to to TO cord-004775-foaf3vyl 182 25 occur occur VB cord-004775-foaf3vyl 182 26 in in IN cord-004775-foaf3vyl 182 27 nature nature NN cord-004775-foaf3vyl 182 28 . . . cord-004775-foaf3vyl 183 1 Only only RB cord-004775-foaf3vyl 183 2 few few JJ cord-004775-foaf3vyl 183 3 data datum NNS cord-004775-foaf3vyl 183 4 on on IN cord-004775-foaf3vyl 183 5 morbidity morbidity NN cord-004775-foaf3vyl 183 6 and and CC cord-004775-foaf3vyl 183 7 mortality mortality NN cord-004775-foaf3vyl 183 8 of of IN cord-004775-foaf3vyl 183 9 torovirus torovirus NNP cord-004775-foaf3vyl 183 10 infections infection NNS cord-004775-foaf3vyl 183 11 are be VBP cord-004775-foaf3vyl 183 12 available available JJ cord-004775-foaf3vyl 183 13 so so RB cord-004775-foaf3vyl 183 14 far far RB cord-004775-foaf3vyl 183 15 . . . cord-004775-foaf3vyl 184 1 The the DT cord-004775-foaf3vyl 184 2 infection infection NN cord-004775-foaf3vyl 184 3 rate rate NN cord-004775-foaf3vyl 184 4 apparently apparently RB cord-004775-foaf3vyl 184 5 can can MD cord-004775-foaf3vyl 184 6 be be VB cord-004775-foaf3vyl 184 7 high high JJ cord-004775-foaf3vyl 184 8 . . . cord-004775-foaf3vyl 185 1 In in IN cord-004775-foaf3vyl 185 2 a a DT cord-004775-foaf3vyl 185 3 beef beef NN cord-004775-foaf3vyl 185 4 herd herd NN cord-004775-foaf3vyl 185 5 in in IN cord-004775-foaf3vyl 185 6 Iowa Iowa NNP cord-004775-foaf3vyl 185 7 from from IN cord-004775-foaf3vyl 185 8 which which WDT cord-004775-foaf3vyl 185 9 BRV BRV NNP cord-004775-foaf3vyl 185 10 1 1 CD cord-004775-foaf3vyl 185 11 was be VBD cord-004775-foaf3vyl 185 12 originally originally RB cord-004775-foaf3vyl 185 13 isolated isolate VBN cord-004775-foaf3vyl 185 14 , , , cord-004775-foaf3vyl 185 15 39 39 CD cord-004775-foaf3vyl 185 16 out out IN cord-004775-foaf3vyl 185 17 of of IN cord-004775-foaf3vyl 185 18 69 69 CD cord-004775-foaf3vyl 185 19 newborn newborn JJ cord-004775-foaf3vyl 185 20 calves calf NNS cord-004775-foaf3vyl 185 21 developed develop VBD cord-004775-foaf3vyl 185 22 diarrhea diarrhea NN cord-004775-foaf3vyl 185 23 and and CC cord-004775-foaf3vyl 185 24 6 6 CD cord-004775-foaf3vyl 185 25 animals animal NNS cord-004775-foaf3vyl 185 26 died die VBD cord-004775-foaf3vyl 185 27 ( ( -LRB- cord-004775-foaf3vyl 185 28 1 1 CD cord-004775-foaf3vyl 185 29 ) ) -RRB- cord-004775-foaf3vyl 185 30 . . . cord-004775-foaf3vyl 186 1 A a DT cord-004775-foaf3vyl 186 2 sudden sudden JJ cord-004775-foaf3vyl 186 3 seroconversion seroconversion NN cord-004775-foaf3vyl 186 4 indicating indicate VBG cord-004775-foaf3vyl 186 5 an an DT cord-004775-foaf3vyl 186 6 infection infection NN cord-004775-foaf3vyl 186 7 with with IN cord-004775-foaf3vyl 186 8 BEV BEV NNP cord-004775-foaf3vyl 186 9 was be VBD cord-004775-foaf3vyl 186 10 noted note VBN cord-004775-foaf3vyl 186 11 in in IN cord-004775-foaf3vyl 186 12 all all DT cord-004775-foaf3vyl 186 13 animals animal NNS cord-004775-foaf3vyl 186 14 of of IN cord-004775-foaf3vyl 186 15 a a DT cord-004775-foaf3vyl 186 16 herd herd NN cord-004775-foaf3vyl 186 17 of of IN cord-004775-foaf3vyl 186 18 20 20 CD cord-004775-foaf3vyl 186 19 foals foal NNS cord-004775-foaf3vyl 186 20 in in IN cord-004775-foaf3vyl 186 21 Switzerland Switzerland NNP cord-004775-foaf3vyl 186 22 ( ( -LRB- cord-004775-foaf3vyl 186 23 18 18 CD cord-004775-foaf3vyl 186 24 ) ) -RRB- cord-004775-foaf3vyl 186 25 ; ; : cord-004775-foaf3vyl 186 26 no no DT cord-004775-foaf3vyl 186 27 clinical clinical JJ cord-004775-foaf3vyl 186 28 signs sign NNS cord-004775-foaf3vyl 186 29 had have VBD cord-004775-foaf3vyl 186 30 been be VBN cord-004775-foaf3vyl 186 31 observed observe VBN cord-004775-foaf3vyl 186 32 in in IN cord-004775-foaf3vyl 186 33 this this DT cord-004775-foaf3vyl 186 34 case case NN cord-004775-foaf3vyl 186 35 , , , cord-004775-foaf3vyl 187 1 In in IN cord-004775-foaf3vyl 187 2 the the DT cord-004775-foaf3vyl 187 3 same same JJ cord-004775-foaf3vyl 187 4 herd herd NN cord-004775-foaf3vyl 187 5 , , , cord-004775-foaf3vyl 187 6 followed follow VBD cord-004775-foaf3vyl 187 7 serologically serologically RB cord-004775-foaf3vyl 187 8 to to IN cord-004775-foaf3vyl 187 9 the the DT cord-004775-foaf3vyl 187 10 age age NN cord-004775-foaf3vyl 187 11 of of IN cord-004775-foaf3vyl 187 12 one one CD cord-004775-foaf3vyl 187 13 year year NN cord-004775-foaf3vyl 187 14 , , , cord-004775-foaf3vyl 187 15 maternal maternal JJ cord-004775-foaf3vyl 187 16 antibodies antibody NNS cord-004775-foaf3vyl 187 17 against against IN cord-004775-foaf3vyl 187 18 BEV BEV NNP cord-004775-foaf3vyl 187 19 were be VBD cord-004775-foaf3vyl 187 20 detected detect VBN cord-004775-foaf3vyl 187 21 . . . cord-004775-foaf3vyl 188 1 Three three CD cord-004775-foaf3vyl 188 2 to to TO cord-004775-foaf3vyl 188 3 6 6 CD cord-004775-foaf3vyl 188 4 months month NNS cord-004775-foaf3vyl 188 5 after after IN cord-004775-foaf3vyl 188 6 birth birth NN cord-004775-foaf3vyl 188 7 their -PRON- PRP$ cord-004775-foaf3vyl 188 8 titers titer NNS cord-004775-foaf3vyl 188 9 had have VBD cord-004775-foaf3vyl 188 10 dropped drop VBN cord-004775-foaf3vyl 188 11 below below IN cord-004775-foaf3vyl 188 12 detection detection NN cord-004775-foaf3vyl 188 13 level level NN cord-004775-foaf3vyl 188 14 . . . cord-004775-foaf3vyl 189 1 In in IN cord-004775-foaf3vyl 189 2 calves calf NNS cord-004775-foaf3vyl 189 3 BRV BRV NNP cord-004775-foaf3vyl 189 4 antibodies antibody NNS cord-004775-foaf3vyl 189 5 as as IN cord-004775-foaf3vyl 189 6 measured measure VBN cord-004775-foaf3vyl 189 7 by by IN cord-004775-foaf3vyl 189 8 ELISA ELISA NNP cord-004775-foaf3vyl 189 9 were be VBD cord-004775-foaf3vyl 189 10 encountered encounter VBN cord-004775-foaf3vyl 189 11 f f NNP cord-004775-foaf3vyl 189 12 ~ ~ NFP cord-004775-foaf3vyl 189 13 om om XX cord-004775-foaf3vyl 189 14 the the DT cord-004775-foaf3vyl 189 15 5th 5th JJ cord-004775-foaf3vyl 189 16 month month NN cord-004775-foaf3vyl 189 17 of of IN cord-004775-foaf3vyl 189 18 age age NN cord-004775-foaf3vyl 189 19 onwards onwards RB cord-004775-foaf3vyl 189 20 ; ; , cord-004775-foaf3vyl 189 21 young young JJ cord-004775-foaf3vyl 189 22 calves calf NNS cord-004775-foaf3vyl 189 23 became become VBD cord-004775-foaf3vyl 189 24 seronegative seronegative JJ cord-004775-foaf3vyl 189 25 about about IN cord-004775-foaf3vyl 189 26 8 8 CD cord-004775-foaf3vyl 189 27 weeks week NNS cord-004775-foaf3vyl 189 28 after after IN cord-004775-foaf3vyl 189 29 birth birth NN cord-004775-foaf3vyl 190 1 ( ( -LRB- cord-004775-foaf3vyl 190 2 VA VA NNP cord-004775-foaf3vyl 190 3 : : : cord-004775-foaf3vyl 190 4 Z Z NNP cord-004775-foaf3vyl 190 5 DE DE NNP cord-004775-foaf3vyl 190 6 BOOM BOOM NNP cord-004775-foaf3vyl 190 7 et et NNP cord-004775-foaf3vyl 190 8 al al NNP cord-004775-foaf3vyl 190 9 . . NNP cord-004775-foaf3vyl 190 10 , , , cord-004775-foaf3vyl 190 11 unpublished unpublished JJ cord-004775-foaf3vyl 190 12 results result NNS cord-004775-foaf3vyl 190 13 ) ) -RRB- cord-004775-foaf3vyl 190 14 . . . cord-004775-foaf3vyl 191 1 Several several JJ cord-004775-foaf3vyl 191 2 intestinal intestinal JJ cord-004775-foaf3vyl 191 3 viruses virus NNS cord-004775-foaf3vyl 191 4 have have VBP cord-004775-foaf3vyl 191 5 been be VBN cord-004775-foaf3vyl 191 6 recognized recognize VBN cord-004775-foaf3vyl 191 7 during during IN cord-004775-foaf3vyl 191 8 the the DT cord-004775-foaf3vyl 191 9 last last JJ cord-004775-foaf3vyl 191 10 fifteen fifteen CD cord-004775-foaf3vyl 191 11 years year NNS cord-004775-foaf3vyl 191 12 ( ( -LRB- cord-004775-foaf3vyl 191 13 e.g. e.g. RB cord-004775-foaf3vyl 191 14 astro- astro- JJ cord-004775-foaf3vyl 191 15 , , , cord-004775-foaf3vyl 191 16 calici- calici- NNP cord-004775-foaf3vyl 191 17 , , , cord-004775-foaf3vyl 191 18 parvo- parvo- NNP cord-004775-foaf3vyl 191 19 , , , cord-004775-foaf3vyl 191 20 corona corona NN cord-004775-foaf3vyl 191 21 - - HYPH cord-004775-foaf3vyl 191 22 viruses virus NNS cord-004775-foaf3vyl 191 23 ) ) -RRB- cord-004775-foaf3vyl 191 24 . . . cord-004775-foaf3vyl 192 1 Enteric enteric JJ cord-004775-foaf3vyl 192 2 infections infection NNS cord-004775-foaf3vyl 192 3 are be VBP cord-004775-foaf3vyl 192 4 also also RB cord-004775-foaf3vyl 192 5 caused cause VBN cord-004775-foaf3vyl 192 6 by by IN cord-004775-foaf3vyl 192 7 the the DT cord-004775-foaf3vyl 192 8 toroviruses toroviruse NNS cord-004775-foaf3vyl 192 9 , , , cord-004775-foaf3vyl 192 10 a a DT cord-004775-foaf3vyl 192 11 group group NN cord-004775-foaf3vyl 192 12 of of IN cord-004775-foaf3vyl 192 13 animal animal NN cord-004775-foaf3vyl 192 14 viruses virus NNS cord-004775-foaf3vyl 192 15 clearly clearly RB cord-004775-foaf3vyl 192 16 separated separate VBN cord-004775-foaf3vyl 192 17 from from IN cord-004775-foaf3vyl 192 18 other other JJ cord-004775-foaf3vyl 192 19 families family NNS cord-004775-foaf3vyl 192 20 by by IN cord-004775-foaf3vyl 192 21 their -PRON- PRP$ cord-004775-foaf3vyl 192 22 distinctive distinctive JJ cord-004775-foaf3vyl 192 23 properties property NNS cord-004775-foaf3vyl 192 24 . . . cord-004775-foaf3vyl 193 1 Three three CD cord-004775-foaf3vyl 193 2 members member NNS cord-004775-foaf3vyl 193 3 are be VBP cord-004775-foaf3vyl 193 4 known know VBN cord-004775-foaf3vyl 193 5 so so RB cord-004775-foaf3vyl 193 6 far far RB cord-004775-foaf3vyl 193 7 , , , cord-004775-foaf3vyl 193 8 but but CC cord-004775-foaf3vyl 193 9 others other NNS cord-004775-foaf3vyl 193 10 will will MD cord-004775-foaf3vyl 193 11 certainly certainly RB cord-004775-foaf3vyl 193 12 be be VB cord-004775-foaf3vyl 193 13 discovered discover VBN cord-004775-foaf3vyl 193 14 . . . cord-004775-foaf3vyl 194 1 Some some DT cord-004775-foaf3vyl 194 2 features feature NNS cord-004775-foaf3vyl 194 3 determined determine VBN cord-004775-foaf3vyl 194 4 for for IN cord-004775-foaf3vyl 194 5 BEV BEV NNP cord-004775-foaf3vyl 194 6 , , , cord-004775-foaf3vyl 194 7 e.g. e.g. RB cord-004775-foaf3vyl 194 8 stability stability NN cord-004775-foaf3vyl 194 9 to to IN cord-004775-foaf3vyl 194 10 low low JJ cord-004775-foaf3vyl 194 11 pH ph NN cord-004775-foaf3vyl 194 12 , , , cord-004775-foaf3vyl 194 13 resistance resistance NN cord-004775-foaf3vyl 194 14 to to IN cord-004775-foaf3vyl 194 15 sodium sodium NN cord-004775-foaf3vyl 194 16 deoxycholate deoxycholate NN cord-004775-foaf3vyl 194 17 , , , cord-004775-foaf3vyl 194 18 trypsin trypsin NN cord-004775-foaf3vyl 194 19 and and CC cord-004775-foaf3vyl 194 20 chymotrypsin chymotrypsin NNP cord-004775-foaf3vyl 194 21 , , , cord-004775-foaf3vyl 194 22 prove prove VB cord-004775-foaf3vyl 194 23 them -PRON- PRP cord-004775-foaf3vyl 194 24 as as RB cord-004775-foaf3vyl 194 25 well well RB cord-004775-foaf3vyl 194 26 adapted adapt VBN cord-004775-foaf3vyl 194 27 to to IN cord-004775-foaf3vyl 194 28 an an DT cord-004775-foaf3vyl 194 29 intestinal intestinal JJ cord-004775-foaf3vyl 194 30 environment environment NN cord-004775-foaf3vyl 194 31 . . . cord-004775-foaf3vyl 195 1 Little little JJ cord-004775-foaf3vyl 195 2 , , , cord-004775-foaf3vyl 195 3 however however RB cord-004775-foaf3vyl 195 4 , , , cord-004775-foaf3vyl 195 5 is be VBZ cord-004775-foaf3vyl 195 6 known know VBN cord-004775-foaf3vyl 195 7 at at IN cord-004775-foaf3vyl 195 8 , , , cord-004775-foaf3vyl 195 9 present present JJ cord-004775-foaf3vyl 195 10 of of IN cord-004775-foaf3vyl 195 11 their -PRON- PRP$ cord-004775-foaf3vyl 195 12 pathogenic pathogenic JJ cord-004775-foaf3vyl 195 13 potency potency NN cord-004775-foaf3vyl 195 14 . . . cord-004775-foaf3vyl 196 1 BEV BEV NNP cord-004775-foaf3vyl 196 2 has have VBZ cord-004775-foaf3vyl 196 3 to to TO cord-004775-foaf3vyl 196 4 be be VB cord-004775-foaf3vyl 196 5 considered consider VBN cord-004775-foaf3vyl 196 6 as as IN cord-004775-foaf3vyl 196 7 a a DT cord-004775-foaf3vyl 196 8 virus virus NN cord-004775-foaf3vyl 196 9 hi hi UH cord-004775-foaf3vyl 196 10 search search NN cord-004775-foaf3vyl 196 11 of of IN cord-004775-foaf3vyl 196 12 disease disease NN cord-004775-foaf3vyl 196 13 and and CC cord-004775-foaf3vyl 196 14 the the DT cord-004775-foaf3vyl 196 15 significance significance NN cord-004775-foaf3vyl 196 16 of of IN cord-004775-foaf3vyl 196 17 torovirus torovirus NNP cord-004775-foaf3vyl 196 18 particles particle NNS cord-004775-foaf3vyl 196 19 seen see VBN cord-004775-foaf3vyl 196 20 in in IN cord-004775-foaf3vyl 196 21 connection connection NN cord-004775-foaf3vyl 196 22 with with IN cord-004775-foaf3vyl 196 23 diarrhea diarrhea NN cord-004775-foaf3vyl 196 24 in in IN cord-004775-foaf3vyl 196 25 humans human NNS cord-004775-foaf3vyl 196 26 needs need VBZ cord-004775-foaf3vyl 196 27 further further JJ cord-004775-foaf3vyl 196 28 study study NN cord-004775-foaf3vyl 196 29 . . . cord-004775-foaf3vyl 197 1 BRV BRV NNP cord-004775-foaf3vyl 197 2 were be VBD cord-004775-foaf3vyl 197 3 shown show VBN cord-004775-foaf3vyl 197 4 to to TO cord-004775-foaf3vyl 197 5 cause cause VB cord-004775-foaf3vyl 197 6 severe severe JJ cord-004775-foaf3vyl 197 7 disease disease NN cord-004775-foaf3vyl 197 8 in in IN cord-004775-foaf3vyl 197 9 newborn newborn JJ cord-004775-foaf3vyl 197 10 calves calf NNS cord-004775-foaf3vyl 197 11 deprived deprive VBN cord-004775-foaf3vyl 197 12 of of IN cord-004775-foaf3vyl 197 13 maternal maternal JJ cord-004775-foaf3vyl 197 14 antibodies antibody NNS cord-004775-foaf3vyl 197 15 . . . cord-004775-foaf3vyl 198 1 It -PRON- PRP cord-004775-foaf3vyl 198 2 is be VBZ cord-004775-foaf3vyl 198 3 unknown unknown JJ cord-004775-foaf3vyl 198 4 , , , cord-004775-foaf3vyl 198 5 however however RB cord-004775-foaf3vyl 198 6 , , , cord-004775-foaf3vyl 198 7 whether whether IN cord-004775-foaf3vyl 198 8 they -PRON- PRP cord-004775-foaf3vyl 198 9 are be VBP cord-004775-foaf3vyl 198 10 able able JJ cord-004775-foaf3vyl 198 11 to to TO cord-004775-foaf3vyl 198 12 induce induce VB cord-004775-foaf3vyl 198 13 symptoms symptom NNS cord-004775-foaf3vyl 198 14 in in IN cord-004775-foaf3vyl 198 15 normally normally RB cord-004775-foaf3vyl 198 16 reared rear VBN cord-004775-foaf3vyl 198 17 calves calf NNS cord-004775-foaf3vyl 198 18 alone alone RB cord-004775-foaf3vyl 198 19 or or CC cord-004775-foaf3vyl 198 20 only only RB cord-004775-foaf3vyl 198 21 in in IN cord-004775-foaf3vyl 198 22 combination combination NN cord-004775-foaf3vyl 198 23 with with IN cord-004775-foaf3vyl 198 24 other other JJ cord-004775-foaf3vyl 198 25 agents agent NNS cord-004775-foaf3vyl 198 26 . . . cord-004775-foaf3vyl 199 1 Apart apart RB cord-004775-foaf3vyl 199 2 from from IN cord-004775-foaf3vyl 199 3 their -PRON- PRP$ cord-004775-foaf3vyl 199 4 eventual eventual JJ cord-004775-foaf3vyl 199 5 clinical clinical JJ cord-004775-foaf3vyl 199 6 and and CC cord-004775-foaf3vyl 199 7 epidemiological epidemiological JJ cord-004775-foaf3vyl 199 8 significance significance NN cord-004775-foaf3vyl 199 9 , , , cord-004775-foaf3vyl 199 10 toroviruses toroviruse NNS cord-004775-foaf3vyl 199 11 will will MD cord-004775-foaf3vyl 199 12 attract attract VB cord-004775-foaf3vyl 199 13 special special JJ cord-004775-foaf3vyl 199 14 interest interest NN cord-004775-foaf3vyl 199 15 due due IN cord-004775-foaf3vyl 199 16 to to IN cord-004775-foaf3vyl 199 17 their -PRON- PRP$ cord-004775-foaf3vyl 199 18 novel novel JJ cord-004775-foaf3vyl 199 19 virion virion NN cord-004775-foaf3vyl 199 20 architecture architecture NN cord-004775-foaf3vyl 199 21 . . . cord-004775-foaf3vyl 200 1 Particles particle NNS cord-004775-foaf3vyl 200 2 with with IN cord-004775-foaf3vyl 200 3 such such PDT cord-004775-foaf3vyl 200 4 a a DT cord-004775-foaf3vyl 200 5 polymorphic polymorphic JJ cord-004775-foaf3vyl 200 6 appearance appearance NN cord-004775-foaf3vyl 200 7 in in IN cord-004775-foaf3vyl 200 8 negatively negatively RB cord-004775-foaf3vyl 200 9 stained stain VBN cord-004775-foaf3vyl 200 10 preparations preparation NNS cord-004775-foaf3vyl 200 11 most most RBS cord-004775-foaf3vyl 200 12 certainly certainly RB cord-004775-foaf3vyl 200 13 have have VBP cord-004775-foaf3vyl 200 14 been be VBN cord-004775-foaf3vyl 200 15 seen see VBN cord-004775-foaf3vyl 200 16 by by IN cord-004775-foaf3vyl 200 17 many many JJ cord-004775-foaf3vyl 200 18 electron electron NN cord-004775-foaf3vyl 200 19 microscopists microscopist NNS cord-004775-foaf3vyl 200 20 and and CC cord-004775-foaf3vyl 200 21 dismissed dismiss VBD cord-004775-foaf3vyl 200 22 as as IN cord-004775-foaf3vyl 200 23 non non JJ cord-004775-foaf3vyl 200 24 viral viral JJ cord-004775-foaf3vyl 200 25 . . . cord-004775-foaf3vyl 201 1 Characterization characterization NN cord-004775-foaf3vyl 201 2 of of IN cord-004775-foaf3vyl 201 3 this this DT cord-004775-foaf3vyl 201 4 family family NN cord-004775-foaf3vyl 201 5 of of IN cord-004775-foaf3vyl 201 6 viruses virus NNS cord-004775-foaf3vyl 201 7 will will MD cord-004775-foaf3vyl 201 8 Studies study NNS cord-004775-foaf3vyl 201 9 with with IN cord-004775-foaf3vyl 201 10 an an DT cord-004775-foaf3vyl 201 11 unclassified unclassified JJ cord-004775-foaf3vyl 201 12 virus virus NN cord-004775-foaf3vyl 201 13 isolated isolate VBN cord-004775-foaf3vyl 201 14 from from IN cord-004775-foaf3vyl 201 15 diarrheic diarrheic NNS cord-004775-foaf3vyl 201 16 calves calf NNS cord-004775-foaf3vyl 201 17 Purification purification NN cord-004775-foaf3vyl 201 18 and and CC cord-004775-foaf3vyl 201 19 partial partial JJ cord-004775-foaf3vyl 201 20 characterization characterization NN cord-004775-foaf3vyl 201 21 of of IN cord-004775-foaf3vyl 201 22 a a DT cord-004775-foaf3vyl 201 23 new new JJ cord-004775-foaf3vyl 201 24 enveloped envelop VBN cord-004775-foaf3vyl 201 25 I -PRON- PRP cord-004775-foaf3vyl 201 26 ~ ~ CD cord-004775-foaf3vyl 201 27 NA NA NNP cord-004775-foaf3vyl 201 28 virus virus NN cord-004775-foaf3vyl 201 29 ( ( -LRB- cord-004775-foaf3vyl 201 30 Berne Berne NNP cord-004775-foaf3vyl 201 31 virus virus NN cord-004775-foaf3vyl 201 32 ) ) -RRB- cord-004775-foaf3vyl 202 1 Toroviridae Toroviridae NNP cord-004775-foaf3vyl 202 2 : : : cord-004775-foaf3vyl 202 3 a a DT cord-004775-foaf3vyl 202 4 taxonomic taxonomic JJ cord-004775-foaf3vyl 202 5 proposal proposal NN cord-004775-foaf3vyl 202 6 PO po NN cord-004775-foaf3vyl 203 1 ~ILENZ ~ILENZ NFP cord-004775-foaf3vyl 203 2 JF JF NNP cord-004775-foaf3vyl 203 3 { { -LRB- cord-004775-foaf3vyl 203 4 1983 1983 CD cord-004775-foaf3vyl 203 5 ) ) -RRB- cord-004775-foaf3vyl 204 1 Diagnostic diagnostic JJ cord-004775-foaf3vyl 204 2 methods method NNS cord-004775-foaf3vyl 204 3 for for IN cord-004775-foaf3vyl 204 4 the the DT cord-004775-foaf3vyl 204 5 newly newly RB cord-004775-foaf3vyl 204 6 discovered discover VBN cord-004775-foaf3vyl 204 7 " " `` cord-004775-foaf3vyl 204 8 Breda Breda NNP cord-004775-foaf3vyl 204 9 " " '' cord-004775-foaf3vyl 204 10 group group NN cord-004775-foaf3vyl 204 11 of of IN cord-004775-foaf3vyl 204 12 calf calf NN cord-004775-foaf3vyl 204 13 enteritis enteritis NN cord-004775-foaf3vyl 204 14 inducing induce VBG cord-004775-foaf3vyl 204 15 viruses virus NNS cord-004775-foaf3vyl 204 16 Studies study NNS cord-004775-foaf3vyl 204 17 of of IN cord-004775-foaf3vyl 204 18 an an DT cord-004775-foaf3vyl 204 19 enteric enteric JJ cord-004775-foaf3vyl 204 20 " " `` cord-004775-foaf3vyl 204 21 Breda Breda NNP cord-004775-foaf3vyl 204 22 " " '' cord-004775-foaf3vyl 204 23 virus virus NN cord-004775-foaf3vyl 204 24 in in IN cord-004775-foaf3vyl 204 25 calves calf NNS cord-004775-foaf3vyl 204 26 . . . cord-004775-foaf3vyl 205 1 62nd 62nd NN cord-004775-foaf3vyl 206 1 Ann Ann NNP cord-004775-foaf3vyl 206 2 Meet Meet NNP cord-004775-foaf3vyl 206 3 Conf Conf NNP cord-004775-foaf3vyl 206 4 Res Res NNP cord-004775-foaf3vyl 206 5 Workers Workers NNP cord-004775-foaf3vyl 206 6 in in IN cord-004775-foaf3vyl 206 7 Anita Anita NNP cord-004775-foaf3vyl 206 8 Dis Dis NNP cord-004775-foaf3vyl 206 9 Nouveaux Nouveaux NNP cord-004775-foaf3vyl 206 10 virus virus NN cord-004775-foaf3vyl 206 11 intervenant intervenant NNP cord-004775-foaf3vyl 206 12 dans dans NNP cord-004775-foaf3vyl 206 13 l'6tio l'6tio NNP cord-004775-foaf3vyl 206 14 - - HYPH cord-004775-foaf3vyl 206 15 logie logie NNP cord-004775-foaf3vyl 206 16 des des FW cord-004775-foaf3vyl 206 17 ent ent NNP cord-004775-foaf3vyl 206 18 ~ ~ NNP cord-004775-foaf3vyl 206 19 rites rite VBZ cord-004775-foaf3vyl 206 20 n6onatales n6onatales NNPS cord-004775-foaf3vyl 206 21 des des FW cord-004775-foaf3vyl 206 22 bovins bovin NNS cord-004775-foaf3vyl 207 1 Nouvelle Nouvelle NNP cord-004775-foaf3vyl 207 2 morphologie morphologie NN cord-004775-foaf3vyl 207 3 virale virale NNP cord-004775-foaf3vyl 207 4 assoei6e assoei6e NNP cord-004775-foaf3vyl 207 5 £ £ NN cord-004775-foaf3vyl 207 6 une une FW cord-004775-foaf3vyl 207 7 infection infection NN cord-004775-foaf3vyl 207 8 bovine bovine NN cord-004775-foaf3vyl 207 9 . . . cord-004775-foaf3vyl 208 1 Note note VB cord-004775-foaf3vyl 208 2 pr61iminaire pr61iminaire NN cord-004775-foaf3vyl 208 3 An an DT cord-004775-foaf3vyl 208 4 enveloped envelop VBN cord-004775-foaf3vyl 208 5 virus virus NN cord-004775-foaf3vyl 208 6 in in IN cord-004775-foaf3vyl 208 7 stools stool NNS cord-004775-foaf3vyl 208 8 of of IN cord-004775-foaf3vyl 208 9 children child NNS cord-004775-foaf3vyl 208 10 and and CC cord-004775-foaf3vyl 208 11 adults adult NNS cord-004775-foaf3vyl 208 12 with with IN cord-004775-foaf3vyl 208 13 gastroenteritis gastroenteritis NN cord-004775-foaf3vyl 208 14 that that WDT cord-004775-foaf3vyl 208 15 , , , cord-004775-foaf3vyl 208 16 resembles resemble VBZ cord-004775-foaf3vyl 208 17 the the DT cord-004775-foaf3vyl 208 18 Breda Breda NNP cord-004775-foaf3vyl 208 19 virus virus NN cord-004775-foaf3vyl 208 20 of of IN cord-004775-foaf3vyl 208 21 calves calf NNS cord-004775-foaf3vyl 208 22 Morphogenesis Morphogenesis NNP cord-004775-foaf3vyl 208 23 of of IN cord-004775-foaf3vyl 208 24 Berne Berne NNP cord-004775-foaf3vyl 208 25 virus virus NN cord-004775-foaf3vyl 208 26 ( ( -LRB- cord-004775-foaf3vyl 209 1 proposed propose VBN cord-004775-foaf3vyl 209 2 f f NNP cord-004775-foaf3vyl 209 3 ~ ~ NFP cord-004775-foaf3vyl 209 4 mily mily NNP cord-004775-foaf3vyl 209 5 Toroviridae Toroviridae NNP cord-004775-foaf3vyl 209 6 ) ) -RRB- cord-004775-foaf3vyl 210 1 Cellular cellular JJ cord-004775-foaf3vyl 210 2 lesions lesion NNS cord-004775-foaf3vyl 210 3 in in IN cord-004775-foaf3vyl 210 4 intestinal intestinal JJ cord-004775-foaf3vyl 210 5 mucosa mucosa NN cord-004775-foaf3vyl 210 6 of of IN cord-004775-foaf3vyl 210 7 gnotobiotic gnotobiotic JJ cord-004775-foaf3vyl 210 8 calves calf NNS cord-004775-foaf3vyl 210 9 experimentally experimentally RB cord-004775-foaf3vyl 210 10 infected infect VBN cord-004775-foaf3vyl 210 11 with with IN cord-004775-foaf3vyl 210 12 a a DT cord-004775-foaf3vyl 210 13 new new JJ cord-004775-foaf3vyl 210 14 unclassified unclassified JJ cord-004775-foaf3vyl 210 15 bovine bovine JJ cord-004775-foaf3vyl 210 16 virus virus NN cord-004775-foaf3vyl 210 17 ( ( -LRB- cord-004775-foaf3vyl 210 18 Breda Breda NNP cord-004775-foaf3vyl 210 19 virus virus NN cord-004775-foaf3vyl 210 20 ) ) -RRB- cord-004775-foaf3vyl 211 1 Astrovirus Astrovirus NNP cord-004775-foaf3vyl 211 2 and and CC cord-004775-foaf3vyl 211 3 Breda Breda NNP cord-004775-foaf3vyl 211 4 virus virus NN cord-004775-foaf3vyl 211 5 infections infection NNS cord-004775-foaf3vyl 211 6 of of IN cord-004775-foaf3vyl 211 7 dome dome NN cord-004775-foaf3vyl 211 8 cell cell NN cord-004775-foaf3vyl 211 9 epithelium epithelium NN cord-004775-foaf3vyl 211 10 of of IN cord-004775-foaf3vyl 211 11 bovine bovine JJ cord-004775-foaf3vyl 211 12 ileum ileum NN cord-004775-foaf3vyl 211 13 A a DT cord-004775-foaf3vyl 211 14 morphologic morphologic JJ cord-004775-foaf3vyl 211 15 study study NN cord-004775-foaf3vyl 211 16 of of IN cord-004775-foaf3vyl 211 17 the the DT cord-004775-foaf3vyl 211 18 replication replication NN cord-004775-foaf3vyl 211 19 of of IN cord-004775-foaf3vyl 211 20 Breda Breda NNP cord-004775-foaf3vyl 211 21 virus virus NN cord-004775-foaf3vyl 211 22 ( ( -LRB- cord-004775-foaf3vyl 211 23 proposed propose VBN cord-004775-foaf3vyl 211 24 family family NN cord-004775-foaf3vyl 211 25 Toroviridae Toroviridae NNP cord-004775-foaf3vyl 211 26 ) ) -RRB- cord-004775-foaf3vyl 211 27 in in IN cord-004775-foaf3vyl 211 28 bovine bovine JJ cord-004775-foaf3vyl 211 29 intestinal intestinal JJ cord-004775-foaf3vyl 211 30 cells cell NNS cord-004775-foaf3vyl 211 31 Berne Berne NNP cord-004775-foaf3vyl 211 32 virus virus NN cord-004775-foaf3vyl 211 33 is be VBZ cord-004775-foaf3vyl 211 34 not not RB cord-004775-foaf3vyl 211 35 " " `` cord-004775-foaf3vyl 211 36 coronavirus coronavirus NN cord-004775-foaf3vyl 211 37 - - HYPH cord-004775-foaf3vyl 211 38 like like IN cord-004775-foaf3vyl 211 39 The the DT cord-004775-foaf3vyl 211 40 nucleocapsid nucleocapsid NN cord-004775-foaf3vyl 211 41 of of IN cord-004775-foaf3vyl 211 42 Berne Berne NNP cord-004775-foaf3vyl 211 43 virus virus NN cord-004775-foaf3vyl 212 1 The the DT cord-004775-foaf3vyl 212 2 surface surface NN cord-004775-foaf3vyl 212 3 proteins protein NNS cord-004775-foaf3vyl 212 4 of of IN cord-004775-foaf3vyl 212 5 Breda Breda NNP cord-004775-foaf3vyl 212 6 virus virus NN cord-004775-foaf3vyl 212 7 Resistance Resistance NNP cord-004775-foaf3vyl 212 8 of of IN cord-004775-foaf3vyl 212 9 Berne Berne NNP cord-004775-foaf3vyl 212 10 virus virus NN cord-004775-foaf3vyl 212 11 to to IN cord-004775-foaf3vyl 212 12 physical physical JJ cord-004775-foaf3vyl 212 13 and and CC cord-004775-foaf3vyl 212 14 chemical chemical NN cord-004775-foaf3vyl 212 15 treatment treatment NN cord-004775-foaf3vyl 212 16 Comparative Comparative NNP cord-004775-foaf3vyl 212 17 studies study NNS cord-004775-foaf3vyl 212 18 on on IN cord-004775-foaf3vyl 212 19 three three CD cord-004775-foaf3vyl 212 20 isolates isolate NNS cord-004775-foaf3vyl 212 21 of of IN cord-004775-foaf3vyl 212 22 Breda Breda NNP cord-004775-foaf3vyl 212 23 virus virus NN cord-004775-foaf3vyl 212 24 of of IN cord-004775-foaf3vyl 212 25 calves calf NNS cord-004775-foaf3vyl 212 26 Antibodies antibody NNS cord-004775-foaf3vyl 212 27 to to IN cord-004775-foaf3vyl 212 28 Berne Berne NNP cord-004775-foaf3vyl 212 29 virus virus NN cord-004775-foaf3vyl 212 30 in in IN cord-004775-foaf3vyl 212 31 horses horse NNS cord-004775-foaf3vyl 212 32 and and CC cord-004775-foaf3vyl 212 33 other other JJ cord-004775-foaf3vyl 212 34 animals animal NNS cord-004775-foaf3vyl 213 1 An an DT cord-004775-foaf3vyl 213 2 ELISA ELISA NNP cord-004775-foaf3vyl 213 3 for for IN cord-004775-foaf3vyl 213 4 serologic serologic NNP cord-004775-foaf3vyl 213 5 studies study NNS cord-004775-foaf3vyl 213 6 on on IN cord-004775-foaf3vyl 213 7 Breda Breda NNP cord-004775-foaf3vyl 213 8 virus virus NN cord-004775-foaf3vyl 214 1 The the DT cord-004775-foaf3vyl 214 2 peplomers peplomer NNS cord-004775-foaf3vyl 214 3 of of IN cord-004775-foaf3vyl 214 4 Berne Berne NNP cord-004775-foaf3vyl 214 5 virus virus NN cord-004775-foaf3vyl 215 1 The the DT cord-004775-foaf3vyl 215 2 haemagglutinating haemagglutinate VBG cord-004775-foaf3vyl 215 3 activity activity NN cord-004775-foaf3vyl 215 4 of of IN cord-004775-foaf3vyl 215 5 Berne Berne NNP cord-004775-foaf3vyl 215 6 virus virus NN cord-004775-foaf3vyl 215 7 provide provide VBP cord-004775-foaf3vyl 215 8 new new JJ cord-004775-foaf3vyl 215 9 insights insight NNS cord-004775-foaf3vyl 215 10 at at IN cord-004775-foaf3vyl 215 11 the the DT cord-004775-foaf3vyl 215 12 molecular molecular JJ cord-004775-foaf3vyl 215 13 level level NN cord-004775-foaf3vyl 215 14 , , , cord-004775-foaf3vyl 215 15 especially especially RB cord-004775-foaf3vyl 215 16 concerning concern VBG cord-004775-foaf3vyl 215 17 virus virus NN cord-004775-foaf3vyl 215 18 replication replication NN cord-004775-foaf3vyl 215 19 . . .