id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-102967-dx0tg077	Mahajan, Lakshmi S.	Mapping RNA dependent RNA polymerase activity and immune gene expression using PRO-seq	2020-06-16		.txt	text/plain	2853	163	57	Coupled to PRO-seq in human blood samples, we propose to use PRO-seq as a single package method to detect (+)ssRNA virus RdRp activity and its interaction with host immune response through transcriptome-wide profiling of leukocyte gene expressions at once. This is different from Drosophila RNA Polymerase II, which appears to have comparable substrate specificity for all 4 biotin-NTPs. The ORF-proximal accumulation coincides with quadruplet rich regions of the template-strand of the DAV genome ( Figure 1D ). From this data, we did not detect significant PRO-seq sequences from (+)ssRNA viral genomes, indicating that none of the individuals had direct viral infections in the blood immune cells. Our PRO-seq data show expression levels of immune-response related genes from human peripheral blood leukocytes. PRO-seq density on DAV genome and base-quadruplet counts.The read count is indicated along the left side of each graph. Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq)	./cache/cord-102967-dx0tg077.txt	./txt/cord-102967-dx0tg077.txt