id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-103041-ymr3e60k	Wu, Yue	Homeostatic mechanisms regulate distinct aspects of cortical circuit dynamics	2019-10-02		.txt	text/plain	7957	423	42	To understand how neural circuits exploit various synaptic plasticity and homeostatic mechanisms to decrease and recover both firing rates and correlations during MD, we built a plastic recurrent network model consisting of randomly connected excitatory and inhibitory spiking neurons (Methods). Based on these experimental findings, besides Hebbian plasticity during training, we modeled these two distinct homeostatic mechanisms following MD: (1) synaptic scaling which acts only on excitatory synapses (Turrigiano et al., 1998; Hengen et al., 2013) , and (2) intrinsic plasticity which modifies the intrinsic excitability of both excitatory and inhibitory neurons (Grubb and Burrone, 2010; Campanac et al., 2013) (Methods) . We speculated that this failure to recover correlations in the model network, despite the recovery of firing rates, could be the result of perturbing the structured connectivity between excitatory neurons within assemblies generated through training (Fig. 3B) .	./cache/cord-103041-ymr3e60k.txt	./txt/cord-103041-ymr3e60k.txt