id author title date pages extension mime words sentences flesch summary cache txt cord-103580-6rf1xs0d Arokiaraj, Mark Christopher A Novel Method of Immunomodulation of Endothelial cells Using Streptococcus Pyogenes and its Lysate 2020-05-15 .txt text/plain 3669 253 44 In this study, a novel method of immune-modulation to modify the endothelial function was studied to modulate the features of the endothelial cells, and thereby to reduce coronary artery disease and other disorders modulated by endothelium. Conclusion There is potential for a novel method of immunomodulation of the endothelial cells, which have pleiotropic functions, using streptococcus pyogenes and its lysates. The study was performed in search of novel applications of streptococcus pyogenes in regulating immune functions, and its related effects on cardiovascular and its pleiotropic functions. When the cells were treated with streptococcus pyogenes' lysate, the levels of BLC -the B lymphocyte chemoattractant protein (CXCL13) was increased. 72 The heat map analysis shows a significant change in more proteins, and thereby it is possible to infer that streptococcus has a role in immune regulation. 78 Our study also reflects the immune regulation changes due to streptococcus pyogenes as well as by its lysate. ./cache/cord-103580-6rf1xs0d.txt ./txt/cord-103580-6rf1xs0d.txt