id author title date pages extension mime words sentences flesch summary cache txt cord-103654-k02z72gb Gamboa Arana, Olga Lucia Dose-dependent enhancement of motion direction discrimination with transcranial magnetic stimulation of visual cortex 2020-06-15 .txt text/plain 5839 241 38 Studies of motion perception are particularly well-suited for exploring mechanisms of TMS due to the superficial location of motion sensitive cortex and its well-characterized spatiotemporal progression of electroencephalographic (EEG) activation described by the P1/N2/P3 Visual Evoked Potential (VEP) complex. For this purpose, we used a three-visit study design consisting of an initial dose-finding session to derive individualized motion coherence thresholds and stimulation parameters based on the onset of the N2 VEP component ("N2-Onset"), followed by two dose-testing sessions during which spTMS was delivered according to the spatial, temporal, and intensity parameters derived from the first session. The overall goal was to map the behavioral and evoked EEG dose-response functions within the constructs of individualized spatiotemporal targeting with the expectation that spTMS delivered at the onset of the N2 component would disrupt motion processes in the brain and lead to monotonic effects across different stimulation intensities. ./cache/cord-103654-k02z72gb.txt ./txt/cord-103654-k02z72gb.txt