id author title date pages extension mime words sentences flesch summary cache txt cord-104109-k36jya0b Das Jana, Indrani Development of a copper-graphene nanocomposite based transparent coating with antiviral activity against influenza virus 2020-09-02 .txt text/plain 1765 116 49 title: Development of a copper-graphene nanocomposite based transparent coating with antiviral activity against influenza virus In this work, we have screened a series of nanoparticles and their composites for antiviral activity using Nano Luciferase based highly sensitive influenza A reporter virus. Extensive material and biological characterization of the nanocomposite suggested a unique metal oxide embedded graphene sheet architecture that can inactivate the virion particles only within 30 minutes of pre-incubation and subsequently interferes with the entry of these virion particles into the host cell. This data 142 suggests that the Nano-luciferase influenza A reporter virus could serve as an excellent tool to study the 143 antiviral activity of various nanoparticles or their nanocomposites used in this study. Briefly, Nano-luciferase influenza A reporter viruses were pre-incubated with the 5uM colloidal 146 suspensions of each of the nanoparticles/ composites or with the vehicle control for 30 minutes at room 147 temperature and subsequently used to infect MDCK cells at an MOI of 0.1. ./cache/cord-104109-k36jya0b.txt ./txt/cord-104109-k36jya0b.txt