id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252097-4kslllaq	Kaur, S.	Local computational methods to improve the interpretability and analysis of cryo-EM maps	2020-06-19		.txt	text/plain	5987	312	54	In this work, we propose 1) approaches to enhance high-resolution features of cryo-EM maps, while preventing map distortions and 2) methods to obtain local B-factors and electron density occupancy maps. Secondly, we also propose approaches to determine local B-factors and density occupancy maps to improve the analysis of cryo-EM reconstructions. The link between the different proposed approaches is the use of the spiral phase transform to estimate a modulation or amplitude map of the cryo-EM reconstruction at different resolutions. In the second row of Figure 2 , we show maps with improved contrast at high-resolution obtained after processing EMD-8441 by the LocSpiral method and by Relion (Fernandez, Luque et al. The common link between all these approaches is the use of the spiral phase transform, which is used to factorize cryo-EM maps into amplitude and phase terms in real space for different resolutions.	./cache/cord-252097-4kslllaq.txt	./txt/cord-252097-4kslllaq.txt