id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-254636-3lr008th	Shishir, Tushar Ahmed	In silico comparative genomics of SARS-CoV-2 to determine the source and diversity of the pathogen in Bangladesh	2020-08-16		.txt	text/plain	2974	171	54	We conducted comparative analysis of publicly available whole-genome sequences of 64 SARS-CoV-2 isolates in Bangladesh and 371 isolates from another 27 countries to predict possible transmission routes of COVID19 to Bangladesh and genomic variations among the viruses. Compared to the ancestral SARS-CoV-2 sequence reported from China, the isolates in Bangladesh had a total of 180 mutations in the coding region of the genome, and 110 of these were missense. We conducted comparative analysis of publicly available genome sequences of SARS-CoV-2 from 27 countries to predict the origin of viruses in Bangladesh by studying a time-4 resolved phylogenetic relationship. Later, we analyzed the variants present in different isolates of Bangladesh to understand the pattern of mutations in relation to the ancestral Wuhan strain, find unique mutations, and possible effect of these mutations on the stability of encoded proteins, and selection pressure on genes.	./cache/cord-254636-3lr008th.txt	./txt/cord-254636-3lr008th.txt