id author title date pages extension mime words sentences flesch summary cache txt cord-262573-wdgbno9p Begum, Feroza Analyses of spike protein from first deposited sequences of SARS-CoV2 from West Bengal, India 2020-05-03 .txt text/plain 1615 96 60 We report one unique mutation at position 723 and the other at 1124 in the S2 domain of spike protein of the isolates from West Bengal only and one mutation downstream of the receptor binding domain at position 614 in S1 domain which was common with the sequence from Gujarat (a state of western part of India). We downloaded the five new SARS-CoV2 sequences from West Bengal (EPI_ISL_430468; EPI_ISL_430467; EPI_ISL_430465; EPI_ISL_430464; EPI_ISL_430466) from GISAID database and the spike protein sequences corresponding to Kerala isolates [2] and Gujarat isolate [3] from the NCBI virus database. Since, currently we have sequences against SARS-CoV2 only from three states in India i.e. Kerala, Gujarat and now West Bengal, we compared all the sequences to detect possible changes ( Figure 2) . This is the first report of mutations of such types in the isolates of the state of West Bengal and further sequencing followed by sequence analyses would help expanding the knowledge about variations of spike protein in human SARS-CoV. ./cache/cord-262573-wdgbno9p.txt ./txt/cord-262573-wdgbno9p.txt