id author title date pages extension mime words sentences flesch summary cache txt cord-263825-g8p2lsr0 Maldonado, Lucas L. Molecular features similarities between SARS-CoV-2, SARS, MERS and key human genes could favour the viral infections and trigger collateral effects 2020-06-25 .txt text/plain 3430 228 61 Since human viruses have codon usage biases that match highly expressed proteins in the tissues they infect and depend on host cell machinery for replication and co-evolution, we selected the genes that are highly expressed in the tissue of human lungs to perform computational studies that permit to compare their molecular features with SARS, SARS-CoV-2 and MERS genes. Furthermore, we provided a list of candidate human genes whose molecular features match those of SARS-CoV-2, SARSand MERS genes, which should be considered to be incorporated into genetic population studies to evaluate thesusceptibility to respiratory viral infections caused by these viruses. SARSand MERS genes, which should be considered to be incorporated into genetic 28 population studies to evaluate thesusceptibility to respiratory viral infections caused by 29 these viruses.The results presented here, settle the basis for further research in the field 30 of human genetics associated with the new viral infection, COVID-19, caused by 31 SARS-CoV-2 and for the development of antiviral preventive methods. ./cache/cord-263825-g8p2lsr0.txt ./txt/cord-263825-g8p2lsr0.txt