id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-264012-q2quyijg	Lim, Su Bin	ACE2-expressing endothelial cells in aging mouse brain	2020-07-11		.txt	text/plain	2133	106	48	Further, scRNA-seq dataset specifically derived from brain vasculature in young adult and aged mice (T3) confirms the elevated ACE2 expression in subsets of the three identified cell types, which consist of 32.8% of the cell populations ( Fig. 1 C) . While our study provides a foundation for a more refined level of analysis of EC and vascular PC, a cell type that remains poorly understood despite its key roles in immune response and microvascular stability [17] , our analyses are limited only to the normal aging mouse and human brains, lacking the context of COVID-19 neuropathology. Despite the works that failed to identify direct signs of SARS-CoV-2 infection in the brains of COVID-19 patients [12, 13] , other lines of evidence support the neurotropism of the virus, as evidenced by experimental platforms leveraging human induced pluripotent stem cell (iPSC)derived dopaminergic neurons [22] and an organotypic brain model [23] .	./cache/cord-264012-q2quyijg.txt	./txt/cord-264012-q2quyijg.txt