id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-267536-rvhwl4ea	Miyashita, L	Traffic-derived particulate matter and angiotensin-converting enzyme 2 expression in human airway epithelial cells	2020-05-27		.txt	text/plain	1093	61	57	title: Traffic-derived particulate matter and angiotensin-converting enzyme 2 expression in human airway epithelial cells Objective To assess the effect of traffic-derived PM10 on human airway epithelial cell ACE2 expression in vitro. Conclusion Traffic-related PM10 increases the expression of the receptor for SARS-CoV-2 in human respiratory epithelial cells. Culture of A549 cells with 5% CSE, a putative positive control, increased ACE2 expression (MFI, n=4, 0 (0 to 28) vs. We also found that traffic-derived PM 10 upregulates ACE2 expression in human primary nasal epithelial cells, suggesting that this response occurs throughout the respiratory tract. First, we did not determine whether increased In conclusion, this study provides the first mechanistic evidence that traffic-derived air pollution increases ACE2 expression in human airway cells and therefore 1 3 vulnerability to SARS-CoV-2 infection.	./cache/cord-267536-rvhwl4ea.txt	./txt/cord-267536-rvhwl4ea.txt