id author title date pages extension mime words sentences flesch summary cache txt cord-268894-amfv3z2y Nguyen-Contant, Phuong S protein-reactive IgG and memory B cell production after human SARS-CoV-2 infection includes broad reactivity to the S2 subunit 2020-07-21 .txt text/plain 4632 269 56 Serum IgG levels specific for SARS-CoV-2 proteins (S, including the RBD 31 and S2 subunit, and nucleocapsid [N] ) and non-SARS-CoV-2 proteins were related to 32 measurements of circulating IgG MBCs. Anti-RBD IgG was absent in unexposed subjects. Serum IgG levels specific for SARS-CoV-2 proteins (S, including the RBD 31 and S2 subunit, and nucleocapsid [N] ) and non-SARS-CoV-2 proteins were related to 32 measurements of circulating IgG MBCs. Anti-RBD IgG was absent in unexposed subjects. Approximately one-third of non-SARS-CoV-140 2-exposed subjects in the healthy donor cohort had low levels of serum IgG against the S and N 141 proteins of SARS-CoV-2, likely reflecting cross-reactivity with seasonal HCoVs ( Figure 1A ). In contrast, IgG MBCs reactive to the S proteins of the HCoVs OC43 and 229E 192 and the control proteins H1 and TTd were detected in nearly 50% or more of non-SARS-CoV-2-193 exposed subjects, consistent with the higher levels of serum IgG against these antigens ( Figure 2E -194 2H) . ./cache/cord-268894-amfv3z2y.txt ./txt/cord-268894-amfv3z2y.txt