id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285592-0in22wzv	Lemoine, Frédéric	COVID-Align: Accurate online alignment of hCoV-19 genomes using a profile HMM	2020-05-25		.txt	text/plain	3755	262	64	Moreover, COVID-Align provides summary statistics, which can be used to determine the sequencing quality and evolutionary novelty of input genomes (e.g. number of new mutations and indels). Unique mutations and indels are possibly due to errors (sequencing, assembly etc.), while new ones (seen at least twice in submitted genomes, for the first time) likely correspond to evolutionary novelties (see Sup. Info. Right: Statistics summary, displaying the number of High and Low Quality genomes, and the number of evolutionary events (mutations, gaps, gap openings, insertions, insertion openings). For each of the input genomes, COVID-Align computes a series of summary statistics to help users analyze their data, remove problematic sequences, and detect those containing evolutionary novelties. When new sequences with confirmed insertions and deletions will be available from emerging genomes, they will be incorporated in the profile and the resulting MSA will closely account for these indels.	./cache/cord-285592-0in22wzv.txt	./txt/cord-285592-0in22wzv.txt