id author title date pages extension mime words sentences flesch summary cache txt cord-289367-zna8qkkv Wirden, Marc Multicenter comparison of the Cobas 6800 system with the RealStar RT-PCR kit for the detection of SARS-CoV-2 2020-06-30 .txt text/plain 1193 72 61 Bland-Altman analysis showed that the mean difference (Cobas® minus RealStar®) was + 3.3 Ct, with a SD of + 2.3 Ct. Conclusions In this comparison, both RealStar® and Cobas® assays provided comparable qualitative results and a high correlation when both tests were positive. Then, each laboratory selected 45 to 49 samples firstly detected 88 using the Cobas 6800 with a stratification according to the Ct of the E gene Cobas results, 89 allowing to cover the whole linear range of the assays. This 207 is a limitation of our study as we did not assessed comparatively the limit of detection of the 208 two methods but the reliability of their Ct values among COBAS 6800 positive samples, 209 excluding those that could be negative with COBAS 6800 and positive with RealStar in this 210 range of low viral loads. RT-PCR assay for the detection of the emerging coronavirus SARS-CoV-2 using a high 278 throughput system ./cache/cord-289367-zna8qkkv.txt ./txt/cord-289367-zna8qkkv.txt