id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-296007-1gsgd22t	Mohseni, Amir Hossein	Inferring MHC interacting SARS-CoV-2 epitopes recognized by TCRs towards designing T cell-based vaccines	2020-09-12		.txt	text/plain	2327	110	64	Our TCR-pMHC models predicted that position 2 of the homologous peptide antigens ( Figure 1A ) related 2 2 0 to TCR-pMHC complex of SARS-CoV-2 as well as SARS-CoV and bat-CoV N proteins prefers the 2 2 1 hydrophobic amino acid residues (e.g. Ile, Leu, Met, and Phe), and the second position of these hit peptides 2 2 2 is an hydrophobic amino acid residue Pro forming five strong VDW forces with residues Y99, V67, M45, 2 2 3 Y7, and F9 and two H-bonds with residues K66 and E63 on MHC molecule ( Figure S2A , left). Visualization of interactions in the atomic level structure of a TCR-pMHC complex in the hit peptide of 2 4 9 SARS-CoV-2 N protein for HLA-E ( Figure S3C ) within 20 and 8 Å was generated on-the-fly using of the homologous peptide antigens of all queries has no detectable binding to both MHC and TCR.	./cache/cord-296007-1gsgd22t.txt	./txt/cord-296007-1gsgd22t.txt