id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312473-7i7efdp2	Sidhom, John-William	Analysis of SARS-CoV-2 specific T-cell receptors in ImmuneCode reveals cross-reactivity to immunodominant Influenza M1 epitope	2020-06-20		.txt	text/plain	1181	62	46	We first examined the distribution of TCRs within the McPas database over the types of pathogens present in the database and cross-referenced the SARS-CoV-2 specific TCRs into the McPas database ( Figure 1A) , and we noted that there was a statistically significant enrichment (from 17.3% to 32.9%) of SARS-CoV-2 specific TCRs that had known specificity to the immunodominant M1 GILGFVFTL epitope We then examined the distribution of TCRs within the ImmuneCode database across the various open readings frames (orfs) and mapped the M1 specific TCRs within this database ( Figure 1B) . In conclusion, while these results are preliminary in a small cohort of individuals, we have identified a set of TCRs that is known to both recognize an immunodominant epitope derived from Influenza and SARS-CoV-2, suggesting that immune control of one infection may play a role in the control of the other.	./cache/cord-312473-7i7efdp2.txt	./txt/cord-312473-7i7efdp2.txt