id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-314445-4cb4a9r5	McNamara, Ryan P.	High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States	2020-06-19		.txt	text/plain	1960	131	53	This study contributes to the understanding of COVID-19 by providing an extensive set of genomes from a non-urban setting and further informs vaccine design by defining D614G as a dominant and emergent SARS-CoV-2 isolate in the U.S. The current COVID-19 pandemic is an urgent public health emergency with over 112,000 deaths in the United States (U.S.) alone. At a CP ≥35 most positive samples still yielded reads that mapped to the target genome 227 and thus allowed detection of SARS-CoV-2 sequences; however, the results were less consistent, 228 and coverage was more variable. In sum, this study generated exhaustive SNV information representing the introduction and 325 spread of SARS-CoV-2 across a suburban low-density area in the Southern U.S. All samples were 326 from symptomatic cases and the majority of genomes clustered with variants that predominate the 327 outbreak in the U.S., rather than Europe or China.	./cache/cord-314445-4cb4a9r5.txt	./txt/cord-314445-4cb4a9r5.txt