id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-318253-vp22xd8p	Parisi, Ortensia Ilaria	“Monoclonal-type” plastic antibodies for SARS-CoV-2 based on Molecularly Imprinted Polymers	2020-05-28		.txt	text/plain	1858	96	38	Our idea is focused on the development of "monoclonal-type" plastic antibodies based on Molecularly Imprinted Polymers (MIPs) able to selectively bind a portion of the novel coronavirus SARS-CoV-2 spike protein to block its function and, thus, the infection process. In the present study, the developed imprinted polymeric nanoparticles were characterized in terms of particles size and distribution by Dynamic Light Scattering (DLS) and the imprinting effect and selectivity were investigated by performing binding experiments using the receptor-binding domain (RBD) of the novel coronavirus and the RBD of SARS-CoV spike protein, respectively. In this context, our idea is to develop "monoclonal-type" plastic antibodies based on Molecularly Imprinted Polymers (MIPs) for the selective recognition and binding of the RBD of the novel coronavirus SARS-CoV-2 in the aim to block the function of its spike protein (Figure 1.) .	./cache/cord-318253-vp22xd8p.txt	./txt/cord-318253-vp22xd8p.txt