id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320417-01l27d99	Wang, Hai-Long	The emergence of inter-clade hybrid SARS-CoV-2 lineages revealed by 2D nucleotide variation mapping	2020-10-14		.txt	text/plain	5013	257	52	I proposed a novel illustrating method using a 2D map to display populations of co-occurring nucleotide variants for intraand inter-viral clades. Using this method, I revealed the emergence of inter-clade hybrid SARS-CoV-2 lineages that are potentially caused by homologous genetic recombination. SARS-CoV-2 is an RNA virus with limited genome length, but its high mutation rate and homologous genetic recombination nonetheless gave rise to exponentially increased variants. This is why all previously reported recombination events of SARS-Cov-2 have relied on clade-defining SNPs. The 2D co-occurring variant mapping is a simple way to display inter-clade hybrid lineages, and it can be used to directly compare distributions of populations for intra-and inter-clade from different geographic locations or the same location but at a different time point. I downloaded ~18,000 SARS-CoV-2 genome sequences from NCBI (on September 2 nd ) and used the same criterion as before to search for inter-clade co-occurring SNP pairs (see method for details).	./cache/cord-320417-01l27d99.txt	./txt/cord-320417-01l27d99.txt