id author title date pages extension mime words sentences flesch summary cache txt cord-321027-64y43o0y Andreano, Emanuele Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients 2020-05-09 .txt text/plain 2287 114 51 The SARS-CoV-2 spike glycoprotein (S-protein) has a pivotal role in viral pathogenesis and it is 63 considered the main target to elicit potent neutralizing antibodies and the focus for the development 64 of therapeutic and prophylactic tools against this virus (3, 4) . Results shown in Table 1 and Figure 1 show that, among the seven donors 97 included in this study, six were able to produce high titers of SARS-CoV-2 S-protein specific 98 antibodies and in particular donors R-042, R-122 and R-188 showed the highest virus neutralizing 99 titers. In the case of SARS-CoV-2, where so far we do not have any effective therapeutic nor prophylactic 154 interventions, mAbs have the possibility to become one of the first drugs that can be used for 155 immediate therapy of any patient testing positive for the virus, and even to provide immediate 156 protection from infection in high risk populations. ./cache/cord-321027-64y43o0y.txt ./txt/cord-321027-64y43o0y.txt