id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-322955-7dw32xby	Kathwate, Gunderao H	In Silico design and characterization of multi-epitopes vaccine for SARS-CoV2 from its spike proteins	2020-06-12		.txt	text/plain	5729	392	47	title: In Silico design and characterization of multi-epitopes vaccine for SARS-CoV2 from its spike proteins Designed vaccine was rich in effective BCR and TCR epitopes screened from the sequence of S-protein of SARS-CoV2. Those properties are calculated by different methods at IEDB server (http://tools.iedb.org/bcell/ )like Kolaskar-Tongaonkar antigenicity scale provide physiology of the amino acid residues(45), Emini Surface accessible score for accessible surface of the epitope(46), Secondary structure of epitopes also has role in antigenicity. High scored and common peptides predicted by various tools were selected for deriving sequence of potential vaccine candidate. We designed a multi-epitopes vaccine construct from S-protein of SARS-CoV2. From various epitopes predicted by the online server based on common sequence and high score three TCR and two BCR epitopes were selected as part of COVID19 vaccine. This vaccine codes epitopes form S protein of SARS-CoV2 virus for T and B cell receptors.	./cache/cord-322955-7dw32xby.txt	./txt/cord-322955-7dw32xby.txt