id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-324344-dxuabscn	Zhao, Xuesen	LY6E Restricts the Entry of Human Coronaviruses, including the currently pandemic SARS-CoV-2	2020-04-05		.txt	text/plain	3152	186	48	In an effort to search for the host cellular protein(s) mediating the differential 29 susceptibility of the two cell lines to HCoV-OC43 infection, we found that ADAP2, GILT and 30 LY6E, three cellular proteins with known activity of interfering virus entry, expressed at 31 significantly higher levels in HepG2 cells. In an effort to search for the host cellular protein(s) mediating the differential 29 susceptibility of the two cell lines to HCoV-OC43 infection, we found that ADAP2, GILT and 30 LY6E, three cellular proteins with known activity of interfering virus entry, expressed at 31 significantly higher levels in HepG2 cells. Finally, the findings that LY6E inhibits human CoV entry cannot be evaded by ectopic 284 expression of membrane-associated serine protease TMPRSS2 and compromised by AmphoB 285 treatment strongly indicate that LY6E modulates virus entry via a distinct mechanism from that 286 IFITM proteins do (Figs.	./cache/cord-324344-dxuabscn.txt	./txt/cord-324344-dxuabscn.txt